id,go_id,definition,name,namespace
57395,GO:0000001,"The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.",mitochondrion inheritance,biological_process
57396,GO:0000006,"Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.",high-affinity zinc transmembrane transporter activity,molecular_function
57397,GO:0000007,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.",low-affinity zinc ion transmembrane transporter activity,molecular_function
57398,GO:0000009,"Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.","alpha-1,6-mannosyltransferase activity",molecular_function
57399,GO:0000010,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.",heptaprenyl diphosphate synthase activity,molecular_function
57400,GO:0000011,"The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.",vacuole inheritance,biological_process
57401,GO:0000012,The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.,single strand break repair,biological_process
57402,GO:0000014,Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.,single-stranded DNA endonuclease activity,molecular_function
57403,GO:0000015,"A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.",phosphopyruvate hydratase complex,cellular_component
57404,GO:0000016,Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.,lactase activity,molecular_function
57405,GO:0000017,"The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.",alpha-glucoside transport,biological_process
57406,GO:0000018,"Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.",regulation of DNA recombination,biological_process
57407,GO:0000019,"Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.",regulation of mitotic recombination,biological_process
57408,GO:0000022,The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.,mitotic spindle elongation,biological_process
57409,GO:0000023,"The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.",maltose metabolic process,biological_process
57410,GO:0000024,The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).,maltose biosynthetic process,biological_process
57411,GO:0000025,The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).,maltose catabolic process,biological_process
57412,GO:0000026,"Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.","alpha-1,2-mannosyltransferase activity",molecular_function
57413,GO:0000027,"The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.",ribosomal large subunit assembly,biological_process
57414,GO:0000028,"The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.",ribosomal small subunit assembly,biological_process
57415,GO:0000030,"Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",mannosyltransferase activity,molecular_function
57416,GO:0000031,Catalysis of the reaction: GDP-alpha-D-mannose + n {[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)}60-(Man9GlcNAc2-[protein] = phosphorylated {[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]-alpha-D-Man-(1->6)}60-(Man9GlcNAc2-[protein] + n GMP + n H+ or GDP-alpha-D-mannose + alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-3-O-(Ser/Thr)-[protein] = alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-[alpha-D-Man-6P-]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-M...,mannosylphosphate transferase activity,molecular_function
57417,GO:0000032,"The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.",cell wall mannoprotein biosynthetic process,biological_process
57418,GO:0000033,"Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.","alpha-1,3-mannosyltransferase activity",molecular_function
57419,GO:0000034,Catalysis of the reaction: adenine + H+ + H2O = hypoxanthine + NH4+.,adenine deaminase activity,molecular_function
57420,GO:0000035,"Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.",acyl binding,molecular_function
57421,GO:0000036,Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.,acyl carrier activity,molecular_function
57422,GO:0000038,The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acid metabolic process,biological_process
57423,GO:0000041,"The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and s...",transition metal ion transport,biological_process
57424,GO:0000045,"The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.",autophagosome assembly,biological_process
57425,GO:0000048,Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme.,peptidyltransferase activity,molecular_function
57426,GO:0000049,Binding to a transfer RNA.,tRNA binding,molecular_function
57427,GO:0000050,"The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.",urea cycle,biological_process
57428,GO:0000054,The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.,ribosomal subunit export from nucleus,biological_process
57429,GO:0000055,The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.,ribosomal large subunit export from nucleus,biological_process
57430,GO:0000056,The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.,ribosomal small subunit export from nucleus,biological_process
57431,GO:0000062,"Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.",fatty-acyl-CoA binding,molecular_function
57432,GO:0000064,"Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.",L-ornithine transmembrane transporter activity,molecular_function
57433,GO:0000070,"The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.",mitotic sister chromatid segregation,biological_process
57434,GO:0000073,"The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB.",initial mitotic spindle pole body separation,biological_process
57435,GO:0000075,A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.,cell cycle checkpoint signaling,biological_process
57436,GO:0000076,"A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.",DNA replication checkpoint signaling,biological_process
57437,GO:0000077,A signal transduction process that contributes to a DNA damage checkpoint.,DNA damage checkpoint signaling,biological_process
57438,GO:0000079,"Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.",regulation of cyclin-dependent protein serine/threonine kinase activity,biological_process
57439,GO:0000080,The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.,mitotic G1 phase,biological_process
57440,GO:0000082,"The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.",G1/S transition of mitotic cell cycle,biological_process
57441,GO:0000084,"The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.",mitotic S phase,biological_process
57442,GO:0000085,The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.,mitotic G2 phase,biological_process
57443,GO:0000086,The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.,G2/M transition of mitotic cell cycle,biological_process
57444,GO:0000087,"A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",mitotic M phase,biological_process
57445,GO:0000088,The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.,mitotic prophase,biological_process
57446,GO:0000089,"The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.",mitotic metaphase,biological_process
57447,GO:0000090,The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.,mitotic anaphase,biological_process
57448,GO:0000091,The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.,mitotic anaphase A,biological_process
57449,GO:0000092,The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.,mitotic anaphase B,biological_process
57450,GO:0000093,The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.,mitotic telophase,biological_process
57451,GO:0000095,"Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.",S-adenosyl-L-methionine transmembrane transporter activity,molecular_function
57452,GO:0000096,The chemical reactions and pathways involving amino acids containing sulfur.,sulfur amino acid metabolic process,biological_process
57453,GO:0000097,The chemical reactions and pathways resulting in the formation of amino acids containing sulfur.,sulfur amino acid biosynthetic process,biological_process
57454,GO:0000098,The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur.,sulfur amino acid catabolic process,biological_process
57455,GO:0000099,"Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.",sulfur amino acid transmembrane transporter activity,molecular_function
57456,GO:0000100,Enables the transfer of S-methylmethionine from one side of a membrane to the other.,S-methylmethionine transmembrane transporter activity,molecular_function
57457,GO:0000101,"The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sulfur amino acid transport,biological_process
57458,GO:0000102,"Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",L-methionine secondary active transmembrane transporter activity,molecular_function
57459,GO:0000103,The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.,sulfate assimilation,biological_process
57460,GO:0000104,Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.,succinate dehydrogenase activity,molecular_function
57461,GO:0000105,"The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.",L-histidine biosynthetic process,biological_process
57462,GO:0000107,Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+.,imidazoleglycerol-phosphate synthase activity,molecular_function
57463,GO:0000109,Any complex formed of proteins that act in nucleotide-excision repair.,nucleotide-excision repair complex,cellular_component
57464,GO:0000110,"One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.",nucleotide-excision repair factor 1 complex,cellular_component
57465,GO:0000111,"One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.",nucleotide-excision repair factor 2 complex,cellular_component
57466,GO:0000112,"One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).",nucleotide-excision repair factor 3 complex,cellular_component
57467,GO:0000113,"One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.",nucleotide-excision repair factor 4 complex,cellular_component
57468,GO:0000118,A protein complex that possesses histone deacetylase activity.,histone deacetylase complex,cellular_component
57469,GO:0000120,A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.,RNA polymerase I transcription regulator complex,cellular_component
57470,GO:0000121,Catalysis of the reaction: H2O + sn-glycerol 1-phosphate = glycerol + phosphate.,sn-glycerol 1-phosphatase activity,molecular_function
57471,GO:0000122,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.",negative regulation of transcription by RNA polymerase II,biological_process
57472,GO:0000123,A protein complex that possesses histone acetyltransferase activity.,histone acetyltransferase complex,cellular_component
57473,GO:0000124,"A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) m...",SAGA complex,cellular_component
57474,GO:0000126,"A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.",transcription factor TFIIIB complex,cellular_component
57475,GO:0000127,"A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.",transcription factor TFIIIC complex,cellular_component
57476,GO:0000128,"The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.",flocculation,biological_process
57477,GO:0000131,The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.,incipient cellular bud site,cellular_component
57478,GO:0000132,A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.,establishment of mitotic spindle orientation,biological_process
57479,GO:0000133,"Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.",polarisome,cellular_component
57480,GO:0000136,"A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.",mannan polymerase complex,cellular_component
57481,GO:0000137,The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.,Golgi cis cisterna,cellular_component
57482,GO:0000138,The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.,Golgi trans cisterna,cellular_component
57483,GO:0000139,The lipid bilayer surrounding any of the compartments of the Golgi apparatus.,Golgi membrane,cellular_component
57484,GO:0000140,Catalysis of the reaction: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP+ = 1-hexadecanoylglycerone 3-phosphate + H+ + NADPH.,acylglycerone-phosphate reductase (NADP+) activity,molecular_function
57485,GO:0000142,"A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.",cellular bud neck contractile ring,cellular_component
57486,GO:0000144,"A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.",cellular bud neck septin ring,cellular_component
57487,GO:0000145,A vesicle tethering complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.,exocyst,cellular_component
57488,GO:0000146,"A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.",microfilament motor activity,molecular_function
57489,GO:0000147,"Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.",actin cortical patch assembly,biological_process
57490,GO:0000148,A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.,"1,3-beta-D-glucan synthase complex",cellular_component
57491,GO:0000149,Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.,SNARE binding,molecular_function
57492,GO:0000150,Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.,DNA strand exchange activity,molecular_function
57493,GO:0000151,A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.,ubiquitin ligase complex,cellular_component
57494,GO:0000152,A ubiquitin ligase complex found in the nucleus.,nuclear ubiquitin ligase complex,cellular_component
57495,GO:0000153,A ubiquitin ligase complex found in the cytoplasm.,cytoplasmic ubiquitin ligase complex,cellular_component
57496,GO:0000154,The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.,rRNA modification,biological_process
57497,GO:0000155,"Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.",phosphorelay sensor kinase activity,molecular_function
57498,GO:0000156,"Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.",phosphorelay response regulator activity,molecular_function
57499,GO:0000159,"A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.",protein phosphatase type 2A complex,cellular_component
57500,GO:0000160,A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.,phosphorelay signal transduction system,biological_process
57501,GO:0000162,"The chemical reactions and pathways resulting in the formation of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; L-tryptophan is synthesized from chorismate via anthranilate.",L-tryptophan biosynthetic process,biological_process
57502,GO:0000164,"A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.",protein phosphatase type 1 complex,cellular_component
57503,GO:0000165,"An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.",MAPK cascade,biological_process
57504,GO:0000166,"Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.",nucleotide binding,molecular_function
57505,GO:0000171,Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.,ribonuclease MRP activity,molecular_function
57506,GO:0000172,"A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.",ribonuclease MRP complex,cellular_component
57507,GO:0000175,Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.,3'-5'-RNA exonuclease activity,molecular_function
57508,GO:0000176,"A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors ...",nuclear exosome (RNase complex),cellular_component
57509,GO:0000177,"A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prim...",cytoplasmic exosome (RNase complex),cellular_component
57510,GO:0000178,"A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex,...",exosome (RNase complex),cellular_component
57511,GO:0000179,"Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.","rRNA (adenine-N6,N6-)-dimethyltransferase activity",molecular_function
57512,GO:0000182,Binding to a DNA sequence encoding a ribosomal RNA.,rDNA binding,molecular_function
57513,GO:0000183,"The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.",rDNA heterochromatin formation,biological_process
57514,GO:0000184,"The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.","nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",biological_process
57515,GO:0000196,"A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the  SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs.",cell integrity MAPK cascade,biological_process
57516,GO:0000209,"Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.",protein polyubiquitination,biological_process
57517,GO:0000210,Catalysis of the reaction: NAD+ + H2O = AMP + NMN.,NAD+ diphosphatase activity,molecular_function
57518,GO:0000212,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.",meiotic spindle organization,biological_process
57519,GO:0000213,"Catalysis of the reaction: pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.",tRNA-intron lyase activity,molecular_function
57520,GO:0000214,"A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.",tRNA-intron endonuclease complex,cellular_component
57521,GO:0000215,"Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.",tRNA 2'-phosphotransferase activity,molecular_function
57522,GO:0000217,"Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.",DNA secondary structure binding,molecular_function
57523,GO:0000220,The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.,"vacuolar proton-transporting V-type ATPase, V0 domain",cellular_component
57524,GO:0000221,The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.,"vacuolar proton-transporting V-type ATPase, V1 domain",cellular_component
57525,GO:0000222,The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.,"plasma membrane proton-transporting V-type ATPase, V0 domain",cellular_component
57526,GO:0000223,The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.,"plasma membrane proton-transporting V-type ATPase, V1 domain",cellular_component
57527,GO:0000224,"Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.",peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity,molecular_function
57528,GO:0000225,"Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.",N-acetylglucosaminylphosphatidylinositol deacetylase activity,molecular_function
57529,GO:0000226,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.",microtubule cytoskeleton organization,biological_process
57530,GO:0000228,A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.,nuclear chromosome,cellular_component
57531,GO:0000234,Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.,phosphoethanolamine N-methyltransferase activity,molecular_function
57532,GO:0000235,Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.,astral microtubule,cellular_component
57533,GO:0000236,"The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.",mitotic prometaphase,biological_process
57534,GO:0000237,"The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.",leptotene,biological_process
57535,GO:0000238,"The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.",zygotene,biological_process
57536,GO:0000239,"The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.",pachytene,biological_process
57537,GO:0000240,"The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.",diplotene,biological_process
57538,GO:0000241,"The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.",diakinesis,biological_process
57539,GO:0000242,A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.,pericentriolar material,cellular_component
57540,GO:0000243,A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.,commitment complex,cellular_component
57541,GO:0000244,The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.,spliceosomal tri-snRNP complex assembly,biological_process
57542,GO:0000245,"The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.",spliceosomal complex assembly,biological_process
57543,GO:0000246,"Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H+ + NADPH.",Delta24(24-1) sterol reductase activity,molecular_function
57544,GO:0000247,Catalysis of the reaction: fecosterol = episterol.,C-8 sterol isomerase activity,molecular_function
57545,GO:0000248,"Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.",C-5 sterol desaturase activity,molecular_function
57546,GO:0000249,"Catalysis of the reaction: 5-dehydroepisterol + H+ + NADPH + O2 = ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP+. This reaction is the introduction of a double bond between the C-22 and C-23 carbons of certain sterols. Also converts sitosterol and 24-epi-campesterol to stigmasterol and brassicasterol, respectively.",C-22 sterol desaturase (NADPH) activity,molecular_function
57547,GO:0000250,"Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.",lanosterol synthase activity,molecular_function
57548,GO:0000252,Catalysis of the reaction: a 3-beta-hydroxysteroid-4-alpha-carboxylate + NADP+ = a 3-oxosteroid + CO2 + NADPH.,3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity,molecular_function
57549,GO:0000253,Catalysis of the reaction: a 3-betahydroxyl sterol + NADP+ = a 3-oxosterol sterol + NADPH + H+.,3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity,molecular_function
57550,GO:0000254,"Catalysis of the reaction: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H+ + 3 O2 = 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O.",C-4 methylsterol oxidase activity,molecular_function
57551,GO:0000255,"The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.",allantoin metabolic process,biological_process
57552,GO:0000256,"The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.",allantoin catabolic process,biological_process
57553,GO:0000257,"Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH4+. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.",nitrilase activity,molecular_function
57554,GO:0000262,A chromosome found in the mitochondrion of a eukaryotic cell.,mitochondrial chromosome,cellular_component
57555,GO:0000266,The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.,mitochondrial fission,biological_process
57556,GO:0000268,"Binding to a peroxisomal targeting sequence, a short stretch of amino acids found in a protein that acts as a signal to localize the protein to the peroxisome.",peroxisome signal sequence receptor activity,molecular_function
57557,GO:0000269,"Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.",toxin export channel activity,molecular_function
57558,GO:0000270,"The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides.",peptidoglycan metabolic process,biological_process
57559,GO:0000271,"The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.",polysaccharide biosynthetic process,biological_process
57560,GO:0000272,"The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.",polysaccharide catabolic process,biological_process
57561,GO:0000277,Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.,[cytochrome c]-lysine N-methyltransferase activity,molecular_function
57562,GO:0000278,"Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.",mitotic cell cycle,biological_process
57563,GO:0000279,"A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.",M phase,biological_process
57564,GO:0000280,"The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",nuclear division,biological_process
57565,GO:0000281,"A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.",mitotic cytokinesis,biological_process
57566,GO:0000282,"The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.",cellular bud site selection,biological_process
57567,GO:0000285,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+.",1-phosphatidylinositol-3-phosphate 5-kinase activity,molecular_function
57568,GO:0000286,Catalysis of the reaction: L-alanine + NAD+ + H2O = pyruvate + NH4+ + NADH + H+.,L-alanine dehydrogenase (NAD+) activity,molecular_function
57569,GO:0000287,Binding to a magnesium (Mg) ion.,magnesium ion binding,molecular_function
57570,GO:0000288,A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.,"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",biological_process
57571,GO:0000289,Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.,nuclear-transcribed mRNA poly(A) tail shortening,biological_process
57572,GO:0000290,Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.,deadenylation-dependent decapping of nuclear-transcribed mRNA,biological_process
57573,GO:0000292,"The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.",RNA fragment catabolic process,biological_process
57574,GO:0000293,Catalysis of the reaction: 2 Fe3+-chelate + electron donor = 2 Fe2+-chelate + electron acceptor.,ferric-chelate reductase activity,molecular_function
57575,GO:0000294,A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends.,"nuclear-transcribed mRNA catabolic process, RNase MRP-dependent",biological_process
57576,GO:0000295,"Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.",adenine nucleotide transmembrane transporter activity,molecular_function
57577,GO:0000296,"The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",spermine transport,biological_process
57578,GO:0000297,"Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.",spermine transmembrane transporter activity,molecular_function
57579,GO:0000298,Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.,endopolyphosphatase activity,molecular_function
57580,GO:0000301,"The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.","retrograde transport, vesicle recycling within Golgi",biological_process
57581,GO:0000302,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.",response to reactive oxygen species,biological_process
57582,GO:0000303,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.",response to superoxide,biological_process
57583,GO:0000304,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.",response to singlet oxygen,biological_process
57584,GO:0000305,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.",response to oxygen radical,biological_process
57585,GO:0000307,Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.,cyclin-dependent protein kinase holoenzyme complex,cellular_component
57586,GO:0000308,Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.,cytoplasmic cyclin-dependent protein kinase holoenzyme complex,cellular_component
57587,GO:0000309,Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + ATP + H+ = diphosphate + NAD+.,nicotinamide-nucleotide adenylyltransferase activity,molecular_function
57588,GO:0000310,Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.,xanthine phosphoribosyltransferase activity,molecular_function
57589,GO:0000311,The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).,plastid large ribosomal subunit,cellular_component
57590,GO:0000312,The smaller of the two subunits of a plastid ribosome.,plastid small ribosomal subunit,cellular_component
57591,GO:0000313,A ribosome contained within a subcellular membrane-bounded organelle.,organellar ribosome,cellular_component
57592,GO:0000314,The smaller of the two subunits of an organellar ribosome.,organellar small ribosomal subunit,cellular_component
57593,GO:0000315,The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).,organellar large ribosomal subunit,cellular_component
57594,GO:0000316,"The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sulfite transmembrane transport,biological_process
57595,GO:0000319,Enables the transfer of sulfite ions from one side of a membrane to the other.,sulfite transmembrane transporter activity,molecular_function
57596,GO:0000320,The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.,re-entry into mitotic cell cycle,biological_process
57597,GO:0000321,The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.,re-entry into mitotic cell cycle after pheromone arrest,biological_process
57598,GO:0000322,"A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.",storage vacuole,cellular_component
57599,GO:0000323,"A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.",lytic vacuole,cellular_component
57600,GO:0000324,"A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of ...",fungal-type vacuole,cellular_component
57601,GO:0000325,"A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.",plant-type vacuole,cellular_component
57602,GO:0000326,A storage vacuole that contains a lytic vacuole; identified in plants.,protein storage vacuole,cellular_component
57603,GO:0000327,"A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.",lytic vacuole within protein storage vacuole,cellular_component
57604,GO:0000328,"The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.",fungal-type vacuole lumen,cellular_component
57605,GO:0000329,"The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.",fungal-type vacuole membrane,cellular_component
57606,GO:0000330,The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.,plant-type vacuole lumen,cellular_component
57607,GO:0000331,"A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory.",contractile vacuole,cellular_component
57608,GO:0000332,Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.,template for synthesis of G-rich strand of telomere DNA activity,molecular_function
57609,GO:0000333,The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.,telomerase catalytic core complex,cellular_component
57610,GO:0000334,"Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.","3-hydroxyanthranilate 3,4-dioxygenase activity",molecular_function
57611,GO:0000338,The removal of a ubiquitin-like protein of the NEDD8 type from a protein.,protein deneddylation,biological_process
57612,GO:0000339,Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.,RNA cap binding,molecular_function
57613,GO:0000340,Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.,RNA 7-methylguanosine cap binding,molecular_function
57614,GO:0000341,"Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.",RNA trimethylguanosine cap binding,molecular_function
57615,GO:0000342,"Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.",RNA cap 4 binding,molecular_function
57616,GO:0000343,"A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.",plastid-encoded plastid RNA polymerase complex A,cellular_component
57617,GO:0000344,"A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-...",plastid-encoded plastid RNA polymerase complex B,cellular_component
57618,GO:0000345,"The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.",cytosolic DNA-directed RNA polymerase complex,cellular_component
57619,GO:0000346,"The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.",transcription export complex,cellular_component
57620,GO:0000347,"The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.",THO complex,cellular_component
57621,GO:0000348,Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.,mRNA branch site recognition,biological_process
57622,GO:0000349,Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.,generation of catalytic spliceosome for first transesterification step,biological_process
57623,GO:0000350,Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.,generation of catalytic spliceosome for second transesterification step,biological_process
57624,GO:0000352,"Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.",trans assembly of SL-containing precatalytic spliceosome,biological_process
57625,GO:0000353,Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.,formation of quadruple SL/U4/U5/U6 snRNP,biological_process
57626,GO:0000354,Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.,cis assembly of pre-catalytic spliceosome,biological_process
57627,GO:0000365,"The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.","mRNA trans splicing, via spliceosome",biological_process
57628,GO:0000366,"The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.",mRNA alternative trans-splicing,biological_process
57629,GO:0000372,"The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine ...",Group I intron splicing,biological_process
57630,GO:0000373,"The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the ...",Group II intron splicing,biological_process
57631,GO:0000374,"The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure...",Group III intron splicing,biological_process
57632,GO:0000375,Splicing of RNA via a series of two transesterification reactions.,"RNA splicing, via transesterification reactions",biological_process
57633,GO:0000376,Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.,"RNA splicing, via transesterification reactions with guanosine as nucleophile",biological_process
57634,GO:0000377,"Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.","RNA splicing, via transesterification reactions with bulged adenosine as nucleophile",biological_process
57635,GO:0000378,"The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.",RNA exon ligation,biological_process
57636,GO:0000379,"RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.",tRNA-type intron splice site recognition and cleavage,biological_process
57637,GO:0000380,The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.,"alternative mRNA splicing, via spliceosome",biological_process
57638,GO:0000381,"Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.","regulation of alternative mRNA splicing, via spliceosome",biological_process
57639,GO:0000384,"Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.",first spliceosomal transesterification activity,molecular_function
57640,GO:0000386,"Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.",second spliceosomal transesterification activity,molecular_function
57641,GO:0000387,"The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.",spliceosomal snRNP assembly,biological_process
57642,GO:0000388,Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).,spliceosome conformational change to release U4 (or U4atac) and U1 (or U11),biological_process
57643,GO:0000389,Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.,mRNA 3'-splice site recognition,biological_process
57644,GO:0000390,"Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.",spliceosomal complex disassembly,biological_process
57645,GO:0000393,"Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.",spliceosomal conformational changes to generate catalytic conformation,biological_process
57646,GO:0000394,"Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.","RNA splicing, via endonucleolytic cleavage and ligation",biological_process
57647,GO:0000395,Recognition of the intron 5'-splice site by components of the assembling spliceosome.,mRNA 5'-splice site recognition,biological_process
57648,GO:0000398,"The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.","mRNA splicing, via spliceosome",biological_process
57649,GO:0000399,Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.,cellular bud neck septin structure,cellular_component
57650,GO:0000400,"Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.",four-way junction DNA binding,molecular_function
57651,GO:0000401,"Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.",open form four-way junction DNA binding,molecular_function
57652,GO:0000402,"Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.",crossed form four-way junction DNA binding,molecular_function
57653,GO:0000403,Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.,Y-form DNA binding,molecular_function
57654,GO:0000404,"Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.",heteroduplex DNA loop binding,molecular_function
57655,GO:0000405,"Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.",bubble DNA binding,molecular_function
57656,GO:0000406,Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA.,double-strand/single-strand DNA junction binding,molecular_function
57657,GO:0000407,Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.,phagophore assembly site,cellular_component
57658,GO:0000408,"A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.",EKC/KEOPS complex,cellular_component
57659,GO:0000409,"Any process involving galactose that modulates the frequency, rate or extent or transcription.",regulation of transcription by galactose,biological_process
57660,GO:0000410,"A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.",carbon catabolite repression of transcription by galactose,biological_process
57661,GO:0000411,Any process involving galactose that activates or increases the rate of transcription.,positive regulation of transcription by galactose,biological_process
57662,GO:0000413,The modification of a protein by cis-trans isomerization of a proline residue.,protein peptidyl-prolyl isomerization,biological_process
57663,GO:0000417,"A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.",HIR complex,cellular_component
57664,GO:0000418,RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The...,RNA polymerase IV complex,cellular_component
57665,GO:0000419,RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit i...,RNA polymerase V complex,cellular_component
57666,GO:0000421,"The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.",autophagosome membrane,cellular_component
57667,GO:0000422,The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.,autophagy of mitochondrion,biological_process
57668,GO:0000423,The selective autophagy process in which a mitochondrion is degraded by macroautophagy.,mitophagy,biological_process
57669,GO:0000424,Degradation of a mitochondrion by microautophagy.,micromitophagy,biological_process
57670,GO:0000425,The selective autophagy process in which a peroxisome is degraded by macroautophagy.,pexophagy,biological_process
57671,GO:0000426,Degradation of a peroxisome by microautophagy.,micropexophagy,biological_process
57672,GO:0000427,"An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.",plastid-encoded plastid RNA polymerase complex,cellular_component
57673,GO:0000428,A protein complex that possesses DNA-directed RNA polymerase activity.,DNA-directed RNA polymerase complex,cellular_component
57674,GO:0000429,"A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.",carbon catabolite regulation of transcription from RNA polymerase II promoter,biological_process
57675,GO:0000430,"Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.",regulation of transcription from RNA polymerase II promoter by glucose,biological_process
57676,GO:0000431,"Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.",regulation of transcription from RNA polymerase II promoter by galactose,biological_process
57677,GO:0000432,Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.,positive regulation of transcription from RNA polymerase II promoter by glucose,biological_process
57678,GO:0000435,Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.,positive regulation of transcription from RNA polymerase II promoter by galactose,biological_process
57679,GO:0000436,"Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.",carbon catabolite activation of transcription from RNA polymerase II promoter,biological_process
57680,GO:0000438,The core TFIIH complex when it is part of the general transcription factor TFIIH.,core TFIIH complex portion of holo TFIIH complex,cellular_component
57681,GO:0000439,"The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.",transcription factor TFIIH core complex,cellular_component
57682,GO:0000440,The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).,core TFIIH complex portion of NEF3 complex,cellular_component
57683,GO:0000444,"A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.",MIS12/MIND type complex,cellular_component
57684,GO:0000445,"The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits.",THO complex part of transcription export complex,cellular_component
57685,GO:0000446,"The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.",nucleoplasmic THO complex,cellular_component
57686,GO:0000447,"Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57687,GO:0000448,"Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57688,GO:0000449,"Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will...","endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)",biological_process
57689,GO:0000450,Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.,"cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)",biological_process
57690,GO:0000451,The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.,rRNA 2'-O-methylation,biological_process
57691,GO:0000452,The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.,snoRNA guided rRNA 2'-O-methylation,biological_process
57692,GO:0000454,The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.,snoRNA guided rRNA pseudouridine synthesis,biological_process
57693,GO:0000455,The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.,enzyme-directed rRNA pseudouridine synthesis,biological_process
57694,GO:0000457,"Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.","endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)",biological_process
57695,GO:0000458,"Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.","endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)",biological_process
57696,GO:0000460,Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.,maturation of 5.8S rRNA,biological_process
57697,GO:0000461,"Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.","endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57698,GO:0000462,"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.","maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57699,GO:0000463,"Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.","maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57700,GO:0000464,"Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.","endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57701,GO:0000465,"Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.","exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57702,GO:0000466,"Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57703,GO:0000467,"Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.","exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57704,GO:0000468,"Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57705,GO:0000470,Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.,maturation of LSU-rRNA,biological_process
57706,GO:0000471,"Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.","endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57707,GO:0000472,"Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.","endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57708,GO:0000473,"Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.","maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57709,GO:0000474,"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.","maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57710,GO:0000475,Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.,maturation of 2S rRNA,biological_process
57711,GO:0000476,Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.,maturation of 4.5S rRNA,biological_process
57712,GO:0000477,"Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57713,GO:0000479,"Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae.","endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57714,GO:0000480,"Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.","endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57715,GO:0000481,Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.,maturation of 5S rRNA,biological_process
57716,GO:0000482,"Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.","maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",biological_process
57717,GO:0000483,"Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species.","endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57718,GO:0000484,"Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57719,GO:0000485,"Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57720,GO:0000486,"Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.","cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57721,GO:0000487,"Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.","maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)",biological_process
57722,GO:0000488,"Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.","maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
57723,GO:0000489,"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.","maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
57724,GO:0000491,"The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.",small nucleolar ribonucleoprotein complex assembly,biological_process
57725,GO:0000492,"The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.",box C/D snoRNP assembly,biological_process
57726,GO:0000493,"The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.",box H/ACA snoRNP assembly,biological_process
57727,GO:0000494,Any process involved in forming the mature 3' end of a box C/D RNA molecule.,box C/D sno(s)RNA 3'-end processing,biological_process
57728,GO:0000495,Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.,box H/ACA sno(s)RNA 3'-end processing,biological_process
57729,GO:0000497,Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.,DNA template activity,molecular_function
57730,GO:0000500,"A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.",RNA polymerase I upstream activating factor complex,cellular_component
57731,GO:0000502,"A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.",proteasome complex,cellular_component
57732,GO:0000506,"An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,cellular_component
57733,GO:0000510,A histone chaperone that carries a H3-H4 histone complex.,H3-H4 histone complex chaperone activity,molecular_function
57734,GO:0000511,A histone chaperone that carries a H2A-H2B histone complex.,H2A-H2B histone complex chaperone activity,molecular_function
57735,GO:0000512,"A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs.",lncRNA-mediated post-transcriptional gene silencing,biological_process
57736,GO:0000513,Binds to and increases the activity of a actin severing protein.,actin severing activator activity,molecular_function
57737,GO:0000514,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-sulfino-L-alanine (cysteinesulfinate) (out) + H+(in) + L-glutamate(in) = 3-sulfino-L-alanine(in) + H+(out) + L-glutamate(out).,"3-sulfino-L-alanine: proton, glutamate antiporter activity",molecular_function
57738,GO:0000515,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-aspartate(in) + L-glutamate(out) = H+(in) + L-aspartate(out) + L-glutamate(in).,"aspartate:glutamate, proton antiporter activity",molecular_function
57739,GO:0000578,"The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.",embryonic axis specification,biological_process
57740,GO:0000700,Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.,mismatch base pair DNA N-glycosylase activity,molecular_function
57741,GO:0000701,"Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.",purine-specific mismatch base pair DNA N-glycosylase activity,molecular_function
57742,GO:0000702,Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.,oxidized base lesion DNA N-glycosylase activity,molecular_function
57743,GO:0000703,"Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.",oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity,molecular_function
57744,GO:0000704,"Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA back...",pyrimidine dimer DNA N-glycosylase activity,molecular_function
57745,GO:0000705,"The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.",achiasmate meiosis I,biological_process
57746,GO:0000706,The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.,meiotic DNA double-strand break processing,biological_process
57747,GO:0000707,"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.",meiotic DNA recombinase assembly,biological_process
57748,GO:0000708,"The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.",meiotic strand invasion,biological_process
57749,GO:0000709,"The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.",meiotic joint molecule formation,biological_process
57750,GO:0000710,"A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.",meiotic mismatch repair,biological_process
57751,GO:0000711,"During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.",meiotic DNA repair synthesis,biological_process
57752,GO:0000712,"The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.",resolution of meiotic recombination intermediates,biological_process
57753,GO:0000713,"During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.",meiotic heteroduplex formation,biological_process
57754,GO:0000714,The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.,meiotic strand displacement,biological_process
57755,GO:0000715,"The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.","nucleotide-excision repair, DNA damage recognition",biological_process
57756,GO:0000716,The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.,"transcription-coupled nucleotide-excision repair, DNA damage recognition",biological_process
57757,GO:0000719,"The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.",photoreactive repair,biological_process
57758,GO:0000720,"The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.",pyrimidine dimer repair by nucleotide-excision repair,biological_process
57759,GO:0000721,"Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.","(R,R)-butanediol dehydrogenase activity",molecular_function
57760,GO:0000722,Any recombinational process that contributes to the maintenance of proper telomeric length.,telomere maintenance via recombination,biological_process
57761,GO:0000723,"Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.",telomere maintenance,biological_process
57762,GO:0000724,"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.",double-strand break repair via homologous recombination,biological_process
57763,GO:0000725,"A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.",recombinational repair,biological_process
57764,GO:0000727,"The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.",double-strand break repair via break-induced replication,biological_process
57765,GO:0000729,The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.,DNA double-strand break processing,biological_process
57766,GO:0000730,"The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.",DNA recombinase assembly,biological_process
57767,GO:0000731,Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.,DNA synthesis involved in DNA repair,biological_process
57768,GO:0000732,The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.,DNA strand displacement,biological_process
57769,GO:0000735,The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.,removal of nonhomologous ends,biological_process
57770,GO:0000736,"During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.","double-strand break repair via single-strand annealing, removal of nonhomologous ends",biological_process
57771,GO:0000740,The joining of 2 or more lipid bilayer membranes that surround the nucleus.,nuclear membrane fusion,biological_process
57772,GO:0000741,The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.,karyogamy,biological_process
57773,GO:0000742,"During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.",karyogamy involved in conjugation with cellular fusion,biological_process
57774,GO:0000743,The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.,nuclear migration involved in conjugation with cellular fusion,biological_process
57775,GO:0000747,A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.,conjugation with cellular fusion,biological_process
57776,GO:0000748,A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange.,conjugation with mutual genetic exchange,biological_process
57777,GO:0000749,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.",response to pheromone triggering conjugation with cellular fusion,biological_process
57778,GO:0000751,The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.,mitotic cell cycle G1 arrest in response to pheromone,biological_process
57779,GO:0000752,The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.,agglutination involved in conjugation with cellular fusion,biological_process
57780,GO:0000753,The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.,cell morphogenesis involved in conjugation with cellular fusion,biological_process
57781,GO:0000755,"A reproductive process in a single-celled organism in which the cytoplasm of two mating cells fuse, resulting in the formation of a single cell containing the combined cellular contents.",cytogamy,biological_process
57782,GO:0000756,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.",response to pheromone regulating conjugation with mutual genetic exchange,biological_process
57783,GO:0000760,"In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.",adaptation to pheromone regulating conjugation with mutual genetic exchange,biological_process
57784,GO:0000761,"During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.",conjugant formation,biological_process
57785,GO:0000762,Unidirectional transfer of genetic information triggered by to a pheromone signal.,pheromone-induced unidirectional conjugation,biological_process
57786,GO:0000765,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.",response to pheromone regulating pheromone-induced unidirectional conjugation,biological_process
57787,GO:0000768,"The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.",syncytium formation by cell-cell fusion,biological_process
57788,GO:0000769,"The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.",syncytium formation by mitosis without cytokinesis,biological_process
57789,GO:0000770,The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.,peptide pheromone export,biological_process
57790,GO:0000772,"The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.",mating pheromone activity,molecular_function
57791,GO:0000773,"Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine. Also catalyzes the transfer of a further methylgroup, producing phosphatidylcholine.",phosphatidyl-N-methylethanolamine N-methyltransferase activity,molecular_function
57792,GO:0000774,Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.,adenyl-nucleotide exchange factor activity,molecular_function
57793,GO:0000775,"The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.","chromosome, centromeric region",cellular_component
57794,GO:0000776,A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.,kinetochore,cellular_component
57795,GO:0000779,"The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.","condensed chromosome, centromeric region",cellular_component
57796,GO:0000781,"The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).","chromosome, telomeric region",cellular_component
57797,GO:0000782,A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome.,telomere cap complex,cellular_component
57798,GO:0000783,A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.,nuclear telomere cap complex,cellular_component
57799,GO:0000785,"The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.",chromatin,cellular_component
57800,GO:0000786,"A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.",nucleosome,cellular_component
57801,GO:0000791,A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation.,euchromatin,cellular_component
57802,GO:0000792,A compact and highly condensed form of chromatin that is refractory to transcription.,heterochromatin,cellular_component
57803,GO:0000793,A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.,condensed chromosome,cellular_component
57804,GO:0000794,A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.,condensed nuclear chromosome,cellular_component
57805,GO:0000795,"A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.",synaptonemal complex,cellular_component
57806,GO:0000796,A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.,condensin complex,cellular_component
57807,GO:0000800,A proteinaceous core found between sister chromatids during meiotic prophase.,lateral element,cellular_component
57808,GO:0000801,A structural unit of the synaptonemal complex found between the lateral elements.,central element,cellular_component
57809,GO:0000802,A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.,transverse filament,cellular_component
57810,GO:0000803,A chromosome involved in sex determination.,sex chromosome,cellular_component
57811,GO:0000804,"The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.",W chromosome,cellular_component
57812,GO:0000805,The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.,X chromosome,cellular_component
57813,GO:0000806,"The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.",Y chromosome,cellular_component
57814,GO:0000807,The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.,Z chromosome,cellular_component
57815,GO:0000808,A multisubunit complex that is located at the replication origins of a chromosome.,origin recognition complex,cellular_component
57816,GO:0000809,A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.,cytoplasmic origin of replication recognition complex,cellular_component
57817,GO:0000810,"Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.",diacylglycerol diphosphate phosphatase activity,molecular_function
57818,GO:0000811,"A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.",GINS complex,cellular_component
57819,GO:0000812,"A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.",Swr1 complex,cellular_component
57820,GO:0000813,An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.,ESCRT I complex,cellular_component
57821,GO:0000814,An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.,ESCRT II complex,cellular_component
57822,GO:0000815,"A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).",ESCRT III complex,cellular_component
57823,GO:0000817,"A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.",COMA complex,cellular_component
57824,GO:0000819,The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.,sister chromatid segregation,biological_process
57825,GO:0000822,Binding to inositol hexakisphosphate.,inositol hexakisphosphate binding,molecular_function
57826,GO:0000823,"Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H+.","inositol-1,4,5-trisphosphate 6-kinase activity",molecular_function
57827,GO:0000824,"Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.","inositol-1,4,5,6-tetrakisphosphate 3-kinase activity",molecular_function
57828,GO:0000825,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.","inositol-1,3,4,5-tetrakisphosphate 6-kinase activity",molecular_function
57829,GO:0000827,"Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.","inositol-1,3,4,5,6-pentakisphosphate kinase activity",molecular_function
57830,GO:0000828,Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.,inositol hexakisphosphate kinase activity,molecular_function
57831,GO:0000829,Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.,diphosphoinositol pentakisphosphate kinase activity,molecular_function
57832,GO:0000830,"Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.",inositol hexakisphosphate 4-kinase activity,molecular_function
57833,GO:0000831,"Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.",inositol hexakisphosphate 6-kinase activity,molecular_function
57834,GO:0000832,"Catalysis of the reaction: 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP.",inositol hexakisphosphate 5-kinase activity,molecular_function
57835,GO:0000833,"Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = ADP + 4,5-bis(diphospho)-1D-myo-inositol (1,2,3,6)tetrakisphosphate.",5-diphosphoinositol pentakisphosphate 4-kinase activity,molecular_function
57836,GO:0000834,"Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = ADP + 5,6-bisdiphosphoinositol-1D-myo-inositol (1,2,3,4)tetrakisphosphate.",5-diphosphoinositol pentakisphosphate 6-kinase activity,molecular_function
57837,GO:0000835,A ubiquitin ligase complex found in the ER.,ER ubiquitin ligase complex,cellular_component
57838,GO:0000836,"A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).",Hrd1p ubiquitin ligase complex,cellular_component
57839,GO:0000837,"A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.",Doa10p ubiquitin ligase complex,cellular_component
57840,GO:0000838,"A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.",Hrd1p ubiquitin ligase ERAD-M complex,cellular_component
57841,GO:0000839,"A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.",Hrd1p ubiquitin ligase ERAD-L complex,cellular_component
57842,GO:0000900,Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.,mRNA regulatory element binding translation repressor activity,molecular_function
57843,GO:0000901,Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.,"translation repressor activity, non-nucleic acid binding",molecular_function
57844,GO:0000902,The developmental process in which the size or shape of a cell is generated and organized.,cell morphogenesis,biological_process
57845,GO:0000905,The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.,sporocarp development involved in asexual reproduction,biological_process
57846,GO:0000906,"Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.","6,7-dimethyl-8-ribityllumazine synthase activity",molecular_function
57847,GO:0000907,Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.,sulfonate dioxygenase activity,molecular_function
57848,GO:0000908,Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.,taurine dioxygenase activity,molecular_function
57849,GO:0000909,"The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sp...",sporocarp development involved in sexual reproduction,biological_process
57850,GO:0000910,The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.,cytokinesis,biological_process
57851,GO:0000911,"The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.",cytokinesis by cell plate formation,biological_process
57852,GO:0000912,"The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.",assembly of actomyosin apparatus involved in cytokinesis,biological_process
57853,GO:0000913,"The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.",preprophase band assembly,biological_process
57854,GO:0000914,"The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).",phragmoplast assembly,biological_process
57855,GO:0000915,"The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.",actomyosin contractile ring assembly,biological_process
57856,GO:0000916,"The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.",actomyosin contractile ring contraction,biological_process
57857,GO:0000917,The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.,division septum assembly,biological_process
57858,GO:0000918,The process of marking the site where a division septum will form.,division septum site selection,biological_process
57859,GO:0000919,"The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.",cell plate assembly,biological_process
57860,GO:0000920,"The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.",septum digestion after cytokinesis,biological_process
57861,GO:0000921,"The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.",septin ring assembly,biological_process
57862,GO:0000922,"Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.",spindle pole,cellular_component
57863,GO:0000923,A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.,equatorial microtubule organizing center,cellular_component
57864,GO:0000930,"A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.",gamma-tubulin complex,cellular_component
57865,GO:0000931,A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.,gamma-tubulin ring complex,cellular_component
57866,GO:0000932,"A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.",P-body,cellular_component
57867,GO:0000933,A cell septum whose formation is independent of nuclear division.,adventitious septum,cellular_component
57868,GO:0000934,A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.,porous cell septum,cellular_component
57869,GO:0000935,A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.,division septum,cellular_component
57870,GO:0000936,A cell septum that forms following nuclear division.,primary cell septum,cellular_component
57871,GO:0000937,"A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).",dolipore septum,cellular_component
57872,GO:0000938,A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.,GARP complex,cellular_component
57873,GO:0000939,"The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.",inner kinetochore,cellular_component
57874,GO:0000940,The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.,outer kinetochore,cellular_component
57875,GO:0000943,"A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.",retrotransposon nucleocapsid,cellular_component
57876,GO:0000956,The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.,nuclear-transcribed mRNA catabolic process,biological_process
57877,GO:0000957,The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.,mitochondrial RNA catabolic process,biological_process
57878,GO:0000958,The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.,mitochondrial mRNA catabolic process,biological_process
57879,GO:0000959,The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.,mitochondrial RNA metabolic process,biological_process
57880,GO:0000960,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.",regulation of mitochondrial RNA catabolic process,biological_process
57881,GO:0000961,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.",negative regulation of mitochondrial RNA catabolic process,biological_process
57882,GO:0000962,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.",positive regulation of mitochondrial RNA catabolic process,biological_process
57883,GO:0000963,The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.,mitochondrial RNA processing,biological_process
57884,GO:0000964,Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.,mitochondrial RNA 5'-end processing,biological_process
57885,GO:0000965,Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.,mitochondrial RNA 3'-end processing,biological_process
57886,GO:0000966,Any process involved in forming the mature 5' end of an RNA molecule.,RNA 5'-end processing,biological_process
57887,GO:0000967,Any process involved in forming the mature 5' end of an rRNA molecule.,rRNA 5'-end processing,biological_process
57888,GO:0000968,An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.,tRNA exon ligation,biological_process
57889,GO:0000972,"The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.",transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery,biological_process
57890,GO:0000973,The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.,post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery,biological_process
57891,GO:0000974,"A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.",Prp19 complex,cellular_component
57892,GO:0000976,"Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.",transcription cis-regulatory region binding,molecular_function
57893,GO:0000977,Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.,RNA polymerase II transcription regulatory region sequence-specific DNA binding,molecular_function
57894,GO:0000978,"Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.",RNA polymerase II cis-regulatory region sequence-specific DNA binding,molecular_function
57895,GO:0000979,Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.,RNA polymerase II core promoter sequence-specific DNA binding,molecular_function
57896,GO:0000981,A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.,"DNA-binding transcription factor activity, RNA polymerase II-specific",molecular_function
57897,GO:0000987,"Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site, located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. Cis-regulatory sites are often referred to as a sequence motifs, enhancers, or silencers.",cis-regulatory region sequence-specific DNA binding,molecular_function
57898,GO:0000992,"Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.",RNA polymerase III cis-regulatory region sequence-specific DNA binding,molecular_function
57899,GO:0000993,"Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.",RNA polymerase II complex binding,molecular_function
57900,GO:0000994,"Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.",RNA polymerase III core binding,molecular_function
57901,GO:0000995,"A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, ...",RNA polymerase III general transcription initiation factor activity,molecular_function
57902,GO:0001000,"Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.",bacterial-type RNA polymerase core enzyme binding,molecular_function
57903,GO:0001001,"Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.",mitochondrial single-subunit type RNA polymerase binding,molecular_function
57904,GO:0001002,"Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.",RNA polymerase III type 1 promoter sequence-specific DNA binding,molecular_function
57905,GO:0001003,Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.,RNA polymerase III type 2 promoter sequence-specific DNA binding,molecular_function
57906,GO:0001006,"Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.",RNA polymerase III type 3 promoter sequence-specific DNA binding,molecular_function
57907,GO:0001014,"The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.",snoRNA transcription by RNA polymerase III,biological_process
57908,GO:0001015,"The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.",snoRNA transcription by RNA polymerase II,biological_process
57909,GO:0001016,Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.,RNA polymerase III transcription regulatory region sequence-specific DNA binding,molecular_function
57910,GO:0001018,Binding to a DNA region that controls the transcription of the mitochondrial DNA.,mitochondrial promoter sequence-specific DNA binding,molecular_function
57911,GO:0001019,Binding to a DNA region that controls transcription by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.,plastid promoter transcription regulatory region sequence-specific DNA binding,molecular_function
57912,GO:0001025,"Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III.",RNA polymerase III general transcription initiation factor binding,molecular_function
57913,GO:0001039,Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.,RNA polymerase III hybrid type promoter sequence-specific DNA binding,molecular_function
57914,GO:0001042,"Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.",RNA polymerase I core binding,molecular_function
57915,GO:0001046,"Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.",core promoter sequence-specific DNA binding,molecular_function
57916,GO:0001048,"Binding to RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production.",RNA polymerase IV core binding,molecular_function
57917,GO:0001049,"Binding to RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing.",RNA polymerase V core binding,molecular_function
57918,GO:0001050,"Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.",single-subunit type RNA polymerase binding,molecular_function
57919,GO:0001051,"Binding to a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.",plastid single-subunit type RNA polymerase binding,molecular_function
57920,GO:0001052,"Binding to a bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit.",plastid PEP RNA polymerase core enzyme binding,molecular_function
57921,GO:0001059,"The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter.",transcription by RNA polymerase IV,biological_process
57922,GO:0001060,"The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter.",transcription by RNA polymerase V,biological_process
57923,GO:0001067,"Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.",transcription regulatory region nucleic acid binding,molecular_function
57924,GO:0001068,"Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.",transcription regulatory region RNA binding,molecular_function
57925,GO:0001069,"Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.",regulatory region RNA binding,molecular_function
57926,GO:0001070,"A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.",RNA-binding transcription regulator activity,molecular_function
57927,GO:0001072,"Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.","transcription antitermination factor activity, RNA binding",molecular_function
57928,GO:0001073,"Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.","transcription antitermination factor activity, DNA binding",molecular_function
57929,GO:0001091,"Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.",RNA polymerase II general transcription initiation factor binding,molecular_function
57930,GO:0001092,"Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.",TFIIA-class transcription factor complex binding,molecular_function
57931,GO:0001093,"Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.",TFIIB-class transcription factor binding,molecular_function
57932,GO:0001094,"Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.",TFIID-class transcription factor complex binding,molecular_function
57933,GO:0001095,"Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.",TFIIE-class transcription factor complex binding,molecular_function
57934,GO:0001096,"Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.",TFIIF-class transcription factor complex binding,molecular_function
57935,GO:0001097,"Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.",TFIIH-class transcription factor complex binding,molecular_function
57936,GO:0001100,Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).,negative regulation of exit from mitosis,biological_process
57937,GO:0001101,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.",response to acid chemical,biological_process
57938,GO:0001108,"Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.",bacterial-type RNA polymerase holo enzyme binding,molecular_function
57939,GO:0001109,"Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.",promoter clearance during DNA-templated transcription,biological_process
57940,GO:0001110,"A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.",RNA polymerase III promoter clearance,biological_process
57941,GO:0001111,"A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.",RNA polymerase II promoter clearance,biological_process
57942,GO:0001112,Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.,DNA-templated transcription open complex formation,biological_process
57943,GO:0001113,Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.,transcription open complex formation at RNA polymerase II promoter,biological_process
57944,GO:0001114,"A macromolecular complex containing protein, DNA, and RNA molecules.",protein-DNA-RNA complex,cellular_component
57945,GO:0001115,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex.",protein-DNA-RNA complex organization,biological_process
57946,GO:0001116,"The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.",protein-DNA-RNA complex assembly,biological_process
57947,GO:0001117,The disaggregation of a protein-DNA-RNA complex into its constituent components.,protein-DNA-RNA complex disassembly,biological_process
57948,GO:0001118,"The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.",transcription ternary complex disassembly,biological_process
57949,GO:0001119,"The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.",protein-DNA-RNA complex remodeling,biological_process
57950,GO:0001120,"The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex.",protein-DNA complex remodeling,biological_process
57951,GO:0001147,"Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.",transcription termination site sequence-specific DNA binding,molecular_function
57952,GO:0001154,"Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.",TFIIIB-class transcription factor complex binding,molecular_function
57953,GO:0001155,"Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters.",TFIIIA-class transcription factor binding,molecular_function
57954,GO:0001156,"Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.",TFIIIC-class transcription factor complex binding,molecular_function
57955,GO:0001161,Binding to an intronic DNA sequence that regulates the transcription of the transcript it is contained within.,intronic transcription regulatory region sequence-specific DNA binding,molecular_function
57956,GO:0001162,Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.,RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding,molecular_function
57957,GO:0001163,Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.,RNA polymerase I transcription regulatory region sequence-specific DNA binding,molecular_function
57958,GO:0001164,"Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.",RNA polymerase I core promoter sequence-specific DNA binding,molecular_function
57959,GO:0001165,"Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element).",RNA polymerase I cis-regulatory region sequence-specific DNA binding,molecular_function
57960,GO:0001171,"A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.",reverse transcription,biological_process
57961,GO:0001172,The synthesis of an RNA transcript from an RNA template.,RNA-templated transcription,biological_process
57962,GO:0001173,Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.,DNA-templated transcriptional start site selection,biological_process
57963,GO:0001174,Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.,transcriptional start site selection at RNA polymerase II promoter,biological_process
57964,GO:0001175,Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.,transcriptional start site selection at RNA polymerase III promoter,biological_process
57965,GO:0001177,"Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.",regulation of transcription open complex formation at RNA polymerase II promoter,biological_process
57966,GO:0001178,"Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.",regulation of transcriptional start site selection at RNA polymerase II promoter,biological_process
57967,GO:0001179,"Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I.",RNA polymerase I general transcription initiation factor binding,molecular_function
57968,GO:0001181,"A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the...",RNA polymerase I general transcription initiation factor activity,molecular_function
57969,GO:0001182,"A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.",RNA polymerase I promoter clearance,biological_process
57970,GO:0001188,"The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.",RNA polymerase I preinitiation complex assembly,biological_process
57971,GO:0001192,"Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.",maintenance of transcriptional fidelity during transcription elongation,biological_process
57972,GO:0001193,"Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.",maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II,biological_process
57973,GO:0001195,"Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.",maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III,biological_process
57974,GO:0001216,A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.,DNA-binding transcription activator activity,molecular_function
57975,GO:0001217,A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.,DNA-binding transcription repressor activity,molecular_function
57976,GO:0001221,"Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.",transcription coregulator binding,molecular_function
57977,GO:0001222,"Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.",transcription corepressor binding,molecular_function
57978,GO:0001223,"Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.",transcription coactivator binding,molecular_function
57979,GO:0001227,A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.,"DNA-binding transcription repressor activity, RNA polymerase II-specific",molecular_function
57980,GO:0001228,A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.,"DNA-binding transcription activator activity, RNA polymerase II-specific",molecular_function
57981,GO:0001325,"Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.",formation of extrachromosomal circular DNA,biological_process
57982,GO:0001326,Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.,replication of extrachromosomal circular DNA,biological_process
57983,GO:0001400,"The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.",mating projection base,cellular_component
57984,GO:0001401,A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.,SAM complex,cellular_component
57985,GO:0001402,Relaying of environmental signals promoting filamentous growth.,signal transduction involved in filamentous growth,biological_process
57986,GO:0001403,"A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.",invasive growth in response to glucose limitation,biological_process
57987,GO:0001405,Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.,"PAM complex, Tim23 associated import motor",cellular_component
57988,GO:0001406,"Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.",glycerophosphodiester transmembrane transporter activity,molecular_function
57989,GO:0001407,"The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.",glycerophosphodiester transmembrane transport,biological_process
57990,GO:0001408,"The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",guanine nucleotide transport,biological_process
57991,GO:0001409,"Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.",guanine nucleotide transmembrane transporter activity,molecular_function
57992,GO:0001410,"The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans.",chlamydospore formation,biological_process
57993,GO:0001411,"The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.",hyphal tip,cellular_component
57994,GO:0001501,"The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).",skeletal system development,biological_process
57995,GO:0001502,The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.,cartilage condensation,biological_process
57996,GO:0001503,"The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.",ossification,biological_process
57997,GO:0001504,The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.,neurotransmitter uptake,biological_process
57998,GO:0001507,The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.,acetylcholine catabolic process in synaptic cleft,biological_process
57999,GO:0001508,"A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.",action potential,biological_process
58000,GO:0001510,Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.,RNA methylation,biological_process
58001,GO:0001512,"Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.",dihydronicotinamide riboside quinone reductase activity,molecular_function
58002,GO:0001514,"The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.",selenocysteine incorporation,biological_process
58003,GO:0001515,"Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.",opioid peptide activity,molecular_function
58004,GO:0001516,"The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.",prostaglandin biosynthetic process,biological_process
58005,GO:0001517,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.",N-acetylglucosamine 6-O-sulfotransferase activity,molecular_function
58006,GO:0001518,A sodium channel in a cell membrane whose opening is governed by the membrane potential.,voltage-gated sodium channel complex,cellular_component
58007,GO:0001519,"The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.",peptide amidation,biological_process
58008,GO:0001520,"A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.",outer dense fiber,cellular_component
58009,GO:0001522,The intramolecular conversion of uridine to pseudouridine within an RNA molecule.,pseudouridine synthesis,biological_process
58010,GO:0001523,"The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.",retinoid metabolic process,biological_process
58011,GO:0001525,Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.,angiogenesis,biological_process
58012,GO:0001527,"Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain microfibrillar-Associated Proteins (MFAPs): MFAP1, MFAP2 (also known as MAGP-1), MFAP3, MFAP4, and MFAP5 (also known as MAGP-2).",microfibril,cellular_component
58013,GO:0001530,Binding to a lipopolysaccharide.,lipopolysaccharide binding,molecular_function
58014,GO:0001531,Binding to an interleukin-21 receptor.,interleukin-21 receptor binding,molecular_function
58015,GO:0001532,Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-21 receptor activity,molecular_function
58016,GO:0001533,"A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).",cornified envelope,cellular_component
58017,GO:0001534,Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.,radial spoke,cellular_component
58018,GO:0001535,Protein complex forming portion of the radial spoke that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary or flagellum axoneme.,radial spoke head,cellular_component
58019,GO:0001536,Protein complex forming the elongated portion of the radial spoke between the base which binds to the A-tubule of each microtubule outer doublet and the neck which connects to the spoke head within the ciliary or flagellum axoneme.,radial spoke stalk,cellular_component
58020,GO:0001537,"Catalysis of the reaction: n 3'-phosphoadenylyl sulfate + dermatan = n adenosine 3',5'-bisphosphate + dermatan 4'-sulfate + n H+.",dermatan 4-sulfotransferase activity,molecular_function
58021,GO:0001539,Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.,cilium or flagellum-dependent cell motility,biological_process
58022,GO:0001540,Binding to an amyloid-beta peptide/protein.,amyloid-beta binding,molecular_function
58023,GO:0001541,"The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.",ovarian follicle development,biological_process
58024,GO:0001542,"The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.",ovulation from ovarian follicle,biological_process
58025,GO:0001543,Disruption of theca cell layer releasing follicular fluid and/or the oocyte.,ovarian follicle rupture,biological_process
58026,GO:0001544,Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).,initiation of primordial ovarian follicle growth,biological_process
58027,GO:0001545,Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).,primary ovarian follicle growth,biological_process
58028,GO:0001546,Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.,preantral ovarian follicle growth,biological_process
58029,GO:0001547,Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.,antral ovarian follicle growth,biological_process
58030,GO:0001548,The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.,follicular fluid formation in ovarian follicle antrum,biological_process
58031,GO:0001549,The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.,cumulus cell differentiation,biological_process
58032,GO:0001550,Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.,ovarian cumulus expansion,biological_process
58033,GO:0001551,Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.,ovarian follicle endowment,biological_process
58034,GO:0001552,A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.,ovarian follicle atresia,biological_process
58035,GO:0001553,The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.,luteinization,biological_process
58036,GO:0001554,"The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.",luteolysis,biological_process
58037,GO:0001555,The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.,oocyte growth,biological_process
58038,GO:0001556,"A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.",oocyte maturation,biological_process
58039,GO:0001558,"Any process that modulates the frequency, rate, extent or direction of cell growth.",regulation of cell growth,biological_process
58040,GO:0001560,"Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.",regulation of cell growth by extracellular stimulus,biological_process
58041,GO:0001561,"A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.",fatty acid alpha-oxidation,biological_process
58042,GO:0001562,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.",response to protozoan,biological_process
58043,GO:0001563,The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.,detection of protozoan,biological_process
58044,GO:0001565,Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.,phorbol ester receptor activity,molecular_function
58045,GO:0001566,Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.,non-kinase phorbol ester receptor activity,molecular_function
58046,GO:0001567,Catalysis of the reaction: AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O.,cholesterol 25-hydroxylase activity,molecular_function
58047,GO:0001568,"The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.",blood vessel development,biological_process
58048,GO:0001569,The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.,branching involved in blood vessel morphogenesis,biological_process
58049,GO:0001570,"The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.",vasculogenesis,biological_process
58050,GO:0001571,Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.,non-tyrosine kinase fibroblast growth factor receptor activity,molecular_function
58051,GO:0001572,"The chemical reactions and pathways resulting in the formation of lactosylceramides that begins with the synthesis of a disaccharide core 4-Gal-beta-1,4-Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units and is also the precursor for the synthesis of gangliosides, globosides and isoglobosides.",lactosylceramide biosynthetic process,biological_process
58052,GO:0001573,"The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.",ganglioside metabolic process,biological_process
58053,GO:0001574,"The chemical reactions and pathways resulting in the formation of gangliosides that begins with the synthesis of a tetrasaccharide core Gal-beta-1,3-GalNAc-beta-1,4-Gal-beta-1,4-Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units including the addition of one or more sialic acid residues.",ganglioside biosynthetic process,biological_process
58054,GO:0001575,"The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.",globoside metabolic process,biological_process
58055,GO:0001576,"The chemical reactions and pathways resulting in the formation of gobliosides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units.",globoside biosynthetic process,biological_process
58056,GO:0001578,A process that results in a parallel arrangement of microtubules.,microtubule bundle formation,biological_process
58057,GO:0001579,"The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.",medium-chain fatty acid transport,biological_process
58058,GO:0001580,The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.,detection of chemical stimulus involved in sensory perception of bitter taste,biological_process
58059,GO:0001581,The series of events required for a sour taste stimulus to be received and converted to a molecular signal.,detection of chemical stimulus involved in sensory perception of sour taste,biological_process
58060,GO:0001582,The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.,detection of chemical stimulus involved in sensory perception of sweet taste,biological_process
58061,GO:0001586,Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.,Gi/o-coupled serotonin receptor activity,molecular_function
58062,GO:0001587,Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.,Gq/11-coupled serotonin receptor activity,molecular_function
58063,GO:0001588,Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.,"dopamine neurotransmitter receptor activity, coupled via Gs",molecular_function
58064,GO:0001591,Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.,"dopamine neurotransmitter receptor activity, coupled via Gi/Go",molecular_function
58065,GO:0001594,"Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.",trace-amine receptor activity,molecular_function
58066,GO:0001595,Combining with angiotensin to initiate a change in cell activity.,angiotensin receptor activity,molecular_function
58067,GO:0001596,"An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.",angiotensin type I receptor activity,molecular_function
58068,GO:0001601,Combining with gut peptide YY to initiate a change in cell activity.,peptide YY receptor activity,molecular_function
58069,GO:0001602,Combining with pancreatic polypeptide PP to initiate a change in cell activity.,pancreatic polypeptide receptor activity,molecular_function
58070,GO:0001604,Combining with urotensin II to initiate a change in cell activity.,urotensin II receptor activity,molecular_function
58071,GO:0001605,Combining with adrenomedullin to initiate a change in cell activity.,adrenomedullin receptor activity,molecular_function
58072,GO:0001607,Combining with neuromedin U to initiate a change in cell activity.,neuromedin U receptor activity,molecular_function
58073,GO:0001608,Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled nucleotide receptor activity,molecular_function
58074,GO:0001609,Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled adenosine receptor activity,molecular_function
58075,GO:0001614,Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,purinergic nucleotide receptor activity,molecular_function
58076,GO:0001616,Combining with ghrelin to initiate a change in cell activity.,growth hormone secretagogue receptor activity,molecular_function
58077,GO:0001618,Combining with a virus component and mediating entry of the virus into the cell.,virus receptor activity,molecular_function
58078,GO:0001621,Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled ADP receptor activity,molecular_function
58079,GO:0001626,"Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.",nociceptin receptor activity,molecular_function
58080,GO:0001631,Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.,cysteinyl leukotriene receptor activity,molecular_function
58081,GO:0001632,"Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.",leukotriene B4 receptor activity,molecular_function
58082,GO:0001634,A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.,pituitary adenylate cyclase-activating polypeptide receptor activity,molecular_function
58083,GO:0001635,Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.,calcitonin gene-related peptide receptor activity,molecular_function
58084,GO:0001637,Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled chemoattractant receptor activity,molecular_function
58085,GO:0001639,"A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.",PLC activating G protein-coupled glutamate receptor activity,molecular_function
58086,GO:0001640,Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.,adenylate cyclase inhibiting G protein-coupled glutamate receptor activity,molecular_function
58087,GO:0001641,"A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.",group II metabotropic glutamate receptor activity,molecular_function
58088,GO:0001642,A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.,group III metabotropic glutamate receptor activity,molecular_function
58089,GO:0001646,"Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",cAMP receptor activity,molecular_function
58090,GO:0001647,Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled cytokinin receptor activity,molecular_function
58091,GO:0001648,"A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.",proteinase-activated receptor activity,molecular_function
58092,GO:0001649,"The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.",osteoblast differentiation,biological_process
58093,GO:0001650,"A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.",fibrillar center,cellular_component
58094,GO:0001651,"A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.",dense fibrillar component,cellular_component
58095,GO:0001652,"A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.",granular component,cellular_component
58096,GO:0001653,Combining with an extracellular or intracellular peptide to initiate a change in cell activity.,peptide receptor activity,molecular_function
58097,GO:0001654,"The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.",eye development,biological_process
58098,GO:0001655,"The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.",urogenital system development,biological_process
58099,GO:0001656,"The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.",metanephros development,biological_process
58100,GO:0001657,"The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.",ureteric bud development,biological_process
58101,GO:0001658,The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.,branching involved in ureteric bud morphogenesis,biological_process
58102,GO:0001659,A homeostatic process in which an organism modulates its internal body temperature.,temperature homeostasis,biological_process
58103,GO:0001660,"The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.",fever generation,biological_process
58104,GO:0001661,A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.,conditioned taste aversion,biological_process
58105,GO:0001662,An acute behavioral change resulting from a perceived external threat.,behavioral fear response,biological_process
58106,GO:0001664,Binding to a G protein-coupled receptor.,G protein-coupled receptor binding,molecular_function
58107,GO:0001665,Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.,"alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",molecular_function
58108,GO:0001666,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.",response to hypoxia,biological_process
58109,GO:0001667,Cell migration that is accomplished by extension and retraction of a pseudopodium.,ameboidal-type cell migration,biological_process
58110,GO:0001669,"A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.",acrosomal vesicle,cellular_component
58111,GO:0001671,Binds to and increases the activity of an ATP hydrolysis activity.,ATPase activator activity,molecular_function
58112,GO:0001673,"The nucleus of a male germ cell, a reproductive cell in males.",male germ cell nucleus,cellular_component
58113,GO:0001674,"The nucleus of the female germ cell, a reproductive cell in females.",female germ cell nucleus,cellular_component
58114,GO:0001675,The formation of the acrosome from the spermatid Golgi.,acrosome assembly,biological_process
58115,GO:0001676,The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid metabolic process,biological_process
58116,GO:0001677,"Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).",formation of translation initiation ternary complex,biological_process
58117,GO:0001678,A homeostatic process involved in the maintenance of a steady state level of glucose within a cell.,intracellular glucose homeostasis,biological_process
58118,GO:0001680,"Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.",tRNA 3'-terminal CCA addition,biological_process
58119,GO:0001681,Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.,sialate O-acetylesterase activity,molecular_function
58120,GO:0001682,"Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.",tRNA 5'-leader removal,biological_process
58121,GO:0001691,"Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.",pseudophosphatase activity,molecular_function
58122,GO:0001692,"The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine metabolic process,biological_process
58123,GO:0001694,"The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine biosynthetic process,biological_process
58124,GO:0001695,"The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine catabolic process,biological_process
58125,GO:0001696,The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.,gastric acid secretion,biological_process
58126,GO:0001697,The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.,histamine-induced gastric acid secretion,biological_process
58127,GO:0001698,The regulated release of gastric acid induced by the interaction of gastrin with its receptor.,gastrin-induced gastric acid secretion,biological_process
58128,GO:0001699,The regulated release of gastric acid by parietal cells in response to acetylcholine.,acetylcholine-induced gastric acid secretion,biological_process
58129,GO:0001700,"The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.",embryonic development via the syncytial blastoderm,biological_process
58130,GO:0001701,"The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.",in utero embryonic development,biological_process
58131,GO:0001702,A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.,gastrulation with mouth forming second,biological_process
58132,GO:0001703,A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.,gastrulation with mouth forming first,biological_process
58133,GO:0001704,"The formation of the ectoderm, mesoderm and endoderm during gastrulation.",formation of primary germ layer,biological_process
58134,GO:0001705,The formation of ectoderm during gastrulation.,ectoderm formation,biological_process
58135,GO:0001706,The formation of the endoderm during gastrulation.,endoderm formation,biological_process
58136,GO:0001707,The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.,mesoderm formation,biological_process
58137,GO:0001708,"The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.",cell fate specification,biological_process
58138,GO:0001709,"The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division.",cell fate determination,biological_process
58139,GO:0001710,The cell differentiation process that results in commitment of a cell to become part of the mesoderm.,mesodermal cell fate commitment,biological_process
58140,GO:0001711,The cell differentiation process that results in commitment of a cell to become part of the endoderm.,endodermal cell fate commitment,biological_process
58141,GO:0001712,The cell differentiation process that results in commitment of a cell to become part of the ectoderm.,ectodermal cell fate commitment,biological_process
58142,GO:0001713,"The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",ectodermal cell fate determination,biological_process
58143,GO:0001714,"The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",endodermal cell fate specification,biological_process
58144,GO:0001715,"The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",ectodermal cell fate specification,biological_process
58145,GO:0001716,Catalysis of the reaction: an L-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4+.,L-amino-acid oxidase activity,molecular_function
58146,GO:0001717,"The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.",conversion of seryl-tRNAsec to selenocys-tRNAsec,biological_process
58147,GO:0001720,"The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).",conversion of lysyl-tRNA to pyrrolysyl-tRNA,biological_process
58148,GO:0001725,"A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.",stress fiber,cellular_component
58149,GO:0001726,Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.,ruffle,cellular_component
58150,GO:0001727,Catalysis of the phosphorylation of a simple or complex lipid.,lipid kinase activity,molecular_function
58151,GO:0001729,Catalysis of the reaction: an N-acylsphing-4-enine + ATP = ADP + an N-acylsphing-4-enine 1-phosphate + H+.,ceramide kinase activity,molecular_function
58152,GO:0001730,Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.,2'-5'-oligoadenylate synthetase activity,molecular_function
58153,GO:0001731,"The joining of the small ribosomal subunit, ternary complex, and mRNA.",formation of translation preinitiation complex,biological_process
58154,GO:0001732,"Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.",formation of cytoplasmic translation initiation complex,biological_process
58155,GO:0001733,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.",galactosylceramide sulfotransferase activity,molecular_function
58156,GO:0001734,"Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.",mRNA m(6)A methyltransferase activity,molecular_function
58157,GO:0001735,Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.,prenylcysteine oxidase activity,molecular_function
58158,GO:0001736,"Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.",establishment of planar polarity,biological_process
58159,GO:0001737,"Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.",establishment of imaginal disc-derived wing hair orientation,biological_process
58160,GO:0001738,The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.,morphogenesis of a polarized epithelium,biological_process
58161,GO:0001739,Chromatin that is part of a sex chromosome.,sex chromatin,cellular_component
58162,GO:0001740,"A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.",Barr body,cellular_component
58163,GO:0001741,"A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.",XY body,cellular_component
58164,GO:0001742,The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.,oenocyte differentiation,biological_process
58165,GO:0001743,The initial developmental process that will lead to the formation of an eye.,lens placode formation,biological_process
58166,GO:0001744,"Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.",insect visual primordium formation,biological_process
58167,GO:0001745,"The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.",compound eye morphogenesis,biological_process
58168,GO:0001746,"The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.",Bolwig's organ morphogenesis,biological_process
58169,GO:0001748,"The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.",insect visual primordium development,biological_process
58170,GO:0001750,The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.,photoreceptor outer segment,cellular_component
58171,GO:0001751,The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.,compound eye photoreceptor cell differentiation,biological_process
58172,GO:0001752,The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.,compound eye photoreceptor fate commitment,biological_process
58173,GO:0001754,"The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.",eye photoreceptor cell differentiation,biological_process
58174,GO:0001755,The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.,neural crest cell migration,biological_process
58175,GO:0001756,The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.,somitogenesis,biological_process
58176,GO:0001757,The process in which individual somites establish identity during embryogenesis.,somite specification,biological_process
58177,GO:0001758,Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.,retinal dehydrogenase (NAD+) activity,molecular_function
58178,GO:0001759,The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.,organ induction,biological_process
58179,GO:0001760,Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.,aminocarboxymuconate-semialdehyde decarboxylase activity,molecular_function
58180,GO:0001761,Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.,beta-alanine transmembrane transporter activity,molecular_function
58181,GO:0001762,"The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",beta-alanine transport,biological_process
58182,GO:0001763,"The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.",morphogenesis of a branching structure,biological_process
58183,GO:0001764,The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.,neuron migration,biological_process
58184,GO:0001765,"The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.",membrane raft assembly,biological_process
58185,GO:0001766,The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.,membrane raft polarization,biological_process
58186,GO:0001767,The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.,establishment of lymphocyte polarity,biological_process
58187,GO:0001768,The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.,establishment of T cell polarity,biological_process
58188,GO:0001769,The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.,establishment of B cell polarity,biological_process
58189,GO:0001770,The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.,establishment of natural killer cell polarity,biological_process
58190,GO:0001771,"The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor int...",immunological synapse formation,biological_process
58191,GO:0001772,"An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.",immunological synapse,cellular_component
58192,GO:0001773,"The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",myeloid dendritic cell activation,biological_process
58193,GO:0001774,"The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",microglial cell activation,biological_process
58194,GO:0001775,A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.,cell activation,biological_process
58195,GO:0001776,The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.,leukocyte homeostasis,biological_process
58196,GO:0001777,The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.,T cell homeostatic proliferation,biological_process
58197,GO:0001778,"The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.",plasma membrane repair,biological_process
58198,GO:0001779,The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.,natural killer cell differentiation,biological_process
58199,GO:0001780,The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.,neutrophil homeostasis,biological_process
58200,GO:0001781,"Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.",neutrophil apoptotic process,biological_process
58201,GO:0001782,The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,B cell homeostasis,biological_process
58202,GO:0001783,"Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.",B cell apoptotic process,biological_process
58203,GO:0001784,Binding to a phosphorylated tyrosine residue within a protein.,phosphotyrosine residue binding,molecular_function
58204,GO:0001785,"Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.",prostaglandin J receptor activity,molecular_function
58205,GO:0001786,"Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.",phosphatidylserine binding,molecular_function
58206,GO:0001787,The expansion of a natural killer cell population by cell division.,natural killer cell proliferation,biological_process
58207,GO:0001788,"Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.",antibody-dependent cellular cytotoxicity,biological_process
58208,GO:0001790,Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.,polymeric immunoglobulin binding,molecular_function
58209,GO:0001791,Binding to an immunoglobulin of the IgM isotype.,IgM binding,molecular_function
58210,GO:0001792,"Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",polymeric immunoglobulin receptor activity,molecular_function
58211,GO:0001793,"Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",IgM receptor activity,molecular_function
58212,GO:0001794,An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.,type IIa hypersensitivity,biological_process
58213,GO:0001795,An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.,type IIb hypersensitivity,biological_process
58214,GO:0001796,"Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.",regulation of type IIa hypersensitivity,biological_process
58215,GO:0001797,"Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.",negative regulation of type IIa hypersensitivity,biological_process
58216,GO:0001798,"Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.",positive regulation of type IIa hypersensitivity,biological_process
58217,GO:0001799,"Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.",regulation of type IIb hypersensitivity,biological_process
58218,GO:0001800,"Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.",negative regulation of type IIb hypersensitivity,biological_process
58219,GO:0001801,"Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.",positive regulation of type IIb hypersensitivity,biological_process
58220,GO:0001802,An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.,type III hypersensitivity,biological_process
58221,GO:0001803,"Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.",regulation of type III hypersensitivity,biological_process
58222,GO:0001804,"Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.",negative regulation of type III hypersensitivity,biological_process
58223,GO:0001805,"Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.",positive regulation of type III hypersensitivity,biological_process
58224,GO:0001806,An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.,type IV hypersensitivity,biological_process
58225,GO:0001807,"Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.",regulation of type IV hypersensitivity,biological_process
58226,GO:0001808,"Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.",negative regulation of type IV hypersensitivity,biological_process
58227,GO:0001809,"Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.",positive regulation of type IV hypersensitivity,biological_process
58228,GO:0001810,"Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.",regulation of type I hypersensitivity,biological_process
58229,GO:0001811,"Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.",negative regulation of type I hypersensitivity,biological_process
58230,GO:0001812,"Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.",positive regulation of type I hypersensitivity,biological_process
58231,GO:0001813,"Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.",regulation of antibody-dependent cellular cytotoxicity,biological_process
58232,GO:0001814,"Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.",negative regulation of antibody-dependent cellular cytotoxicity,biological_process
58233,GO:0001815,"Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.",positive regulation of antibody-dependent cellular cytotoxicity,biological_process
58234,GO:0001816,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",cytokine production,biological_process
58235,GO:0001817,"Any process that modulates the frequency, rate, or extent of production of a cytokine.",regulation of cytokine production,biological_process
58236,GO:0001818,"Any process that stops, prevents, or reduces the rate of production of a cytokine.",negative regulation of cytokine production,biological_process
58237,GO:0001819,"Any process that activates or increases the frequency, rate or extent of production of a cytokine.",positive regulation of cytokine production,biological_process
58238,GO:0001820,"The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.",serotonin secretion,biological_process
58239,GO:0001821,The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.,histamine secretion,biological_process
58240,GO:0001822,"The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.",kidney development,biological_process
58241,GO:0001823,"The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.",mesonephros development,biological_process
58242,GO:0001824,"The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence.",blastocyst development,biological_process
58243,GO:0001825,The initial formation of a blastocyst from a solid ball of cells known as a morula.,blastocyst formation,biological_process
58244,GO:0001826,The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.,inner cell mass cell differentiation,biological_process
58245,GO:0001827,The cell fate commitment of precursor cells that will become inner cell mass cells.,inner cell mass cell fate commitment,biological_process
58246,GO:0001828,The morphogenesis of cells in the inner cell mass.,inner cell mass cellular morphogenesis,biological_process
58247,GO:0001829,The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.,trophectodermal cell differentiation,biological_process
58248,GO:0001830,The cell fate commitment of precursor cells that will become trophectoderm cells.,trophectodermal cell fate commitment,biological_process
58249,GO:0001831,The morphogenesis of trophectoderm cells.,trophectodermal cellular morphogenesis,biological_process
58250,GO:0001832,An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.,blastocyst growth,biological_process
58251,GO:0001833,The proliferation of cells in the inner cell mass.,inner cell mass cell proliferation,biological_process
58252,GO:0001834,The proliferation of cells in the trophectoderm.,trophectodermal cell proliferation,biological_process
58253,GO:0001835,The hatching of the cellular blastocyst from the zona pellucida.,blastocyst hatching,biological_process
58254,GO:0001836,"The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.",release of cytochrome c from mitochondria,biological_process
58255,GO:0001837,"A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",epithelial to mesenchymal transition,biological_process
58256,GO:0001838,The morphogenesis of an embryonic epithelium into a tube-shaped structure.,embryonic epithelial tube formation,biological_process
58257,GO:0001839,The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.,neural plate morphogenesis,biological_process
58258,GO:0001840,"The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.",neural plate development,biological_process
58259,GO:0001841,The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.,neural tube formation,biological_process
58260,GO:0001842,The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.,neural fold formation,biological_process
58261,GO:0001843,"The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.",neural tube closure,biological_process
58262,GO:0001845,"The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.",phagolysosome assembly,biological_process
58263,GO:0001846,"Binding to an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.",opsonin binding,molecular_function
58264,GO:0001847,Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,opsonin receptor activity,molecular_function
58265,GO:0001848,Binding to a component or product of the complement cascade.,complement binding,molecular_function
58266,GO:0001849,"Binding to a C1q complex, a component of the classical complement cascade.",complement component C1q complex binding,molecular_function
58267,GO:0001850,Binding to a C3a product of the complement cascade.,complement component C3a binding,molecular_function
58268,GO:0001851,Binding to a C3b product of the complement cascade.,complement component C3b binding,molecular_function
58269,GO:0001852,Binding to a iC3b product of the complement cascade.,complement component iC3b binding,molecular_function
58270,GO:0001853,Binding to a C3dg product of the complement cascade.,complement component C3dg binding,molecular_function
58271,GO:0001854,Binding to a C3d product of the complement cascade.,complement component C3d binding,molecular_function
58272,GO:0001855,Binding to a C4b product of the classical complement cascade.,complement component C4b binding,molecular_function
58273,GO:0001856,Binding to a C5a product of the complement cascade.,complement component C5a binding,molecular_function
58274,GO:0001857,"Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",complement component C1q receptor activity,molecular_function
58275,GO:0001858,Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component iC3b receptor activity,molecular_function
58276,GO:0001859,Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C3dg receptor activity,molecular_function
58277,GO:0001860,Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C3d receptor activity,molecular_function
58278,GO:0001861,Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C4b receptor activity,molecular_function
58279,GO:0001862,"Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.",collectin binding,molecular_function
58280,GO:0001863,Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,collectin receptor activity,molecular_function
58281,GO:0001864,"Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.",pentraxin binding,molecular_function
58282,GO:0001865,The process in which a precursor cell type acquires the specialized features of a NK T cell.,NK T cell differentiation,biological_process
58283,GO:0001866,The expansion of a NK T cell population by cell division.,NK T cell proliferation,biological_process
58284,GO:0001867,Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.,"complement activation, lectin pathway",biological_process
58285,GO:0001868,"Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.","regulation of complement activation, lectin pathway",biological_process
58286,GO:0001869,"Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.","negative regulation of complement activation, lectin pathway",biological_process
58287,GO:0001870,"Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.","positive regulation of complement activation, lectin pathway",biological_process
58288,GO:0001872,Binding to a (1->3)-beta-D-glucan.,(1->3)-beta-D-glucan binding,molecular_function
58289,GO:0001873,Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.,polysaccharide immune receptor activity,molecular_function
58290,GO:0001874,Combining with (1->3)-beta-D-glucans to initiate an innate immune response.,(1->3)-beta-D-glucan immune receptor activity,molecular_function
58291,GO:0001875,"Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.",lipopolysaccharide immune receptor activity,molecular_function
58292,GO:0001876,Binding to lipoarabinomannan.,lipoarabinomannan binding,molecular_function
58293,GO:0001877,Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.,lipoarabinomannan immune receptor activity,molecular_function
58294,GO:0001878,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.",response to yeast,biological_process
58295,GO:0001879,The series of events in which a stimulus from a yeast is received and converted into a molecular signal.,detection of yeast,biological_process
58296,GO:0001880,"The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.",Mullerian duct regression,biological_process
58297,GO:0001881,The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.,receptor recycling,biological_process
58298,GO:0001882,"Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.",nucleoside binding,molecular_function
58299,GO:0001883,"Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.",purine nucleoside binding,molecular_function
58300,GO:0001884,"Binding to a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.",pyrimidine nucleoside binding,molecular_function
58301,GO:0001885,"The progression of an endothelial cell over time, from its formation to the mature structure.",endothelial cell development,biological_process
58302,GO:0001886,The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.,endothelial cell morphogenesis,biological_process
58303,GO:0001887,"The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.",selenium compound metabolic process,biological_process
58304,GO:0001888,Catalysis of the reaction: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.,glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity,molecular_function
58305,GO:0001889,"The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.",liver development,biological_process
58306,GO:0001890,"The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.",placenta development,biological_process
58307,GO:0001891,An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.,phagocytic cup,cellular_component
58308,GO:0001892,"The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.",embryonic placenta development,biological_process
58309,GO:0001893,"Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.",maternal placenta development,biological_process
58310,GO:0001894,"A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.",tissue homeostasis,biological_process
58311,GO:0001895,"A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.",retina homeostasis,biological_process
58312,GO:0001896,A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.,autolysis,biological_process
58313,GO:0001897,A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated cytolysis of host cell,biological_process
58314,GO:0001905,The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.,activation of membrane attack complex,biological_process
58315,GO:0001906,"Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.",cell killing,biological_process
58316,GO:0001907,A process mediated by a symbiont that results in the death of a cell in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated killing of host cell,biological_process
58317,GO:0001909,The directed killing of a target cell by a leukocyte.,leukocyte mediated cytotoxicity,biological_process
58318,GO:0001910,"Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.",regulation of leukocyte mediated cytotoxicity,biological_process
58319,GO:0001911,"Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.",negative regulation of leukocyte mediated cytotoxicity,biological_process
58320,GO:0001912,"Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.",positive regulation of leukocyte mediated cytotoxicity,biological_process
58321,GO:0001913,The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,T cell mediated cytotoxicity,biological_process
58322,GO:0001914,"Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.",regulation of T cell mediated cytotoxicity,biological_process
58323,GO:0001915,"Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.",negative regulation of T cell mediated cytotoxicity,biological_process
58324,GO:0001916,"Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.",positive regulation of T cell mediated cytotoxicity,biological_process
58325,GO:0001917,"The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.",photoreceptor inner segment,cellular_component
58326,GO:0001918,Binding to a farnesylated protein.,farnesylated protein binding,molecular_function
58327,GO:0001919,"Any process that modulates the frequency, rate, or extent of receptor recycling.",regulation of receptor recycling,biological_process
58328,GO:0001920,"Any process that stops, prevents, or reduces the rate of receptor recycling.",negative regulation of receptor recycling,biological_process
58329,GO:0001921,"Any process that activates or increases the frequency, rate or extent of receptor recycling.",positive regulation of receptor recycling,biological_process
58330,GO:0001922,"The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.",B-1 B cell homeostasis,biological_process
58331,GO:0001923,"The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.",B-1 B cell differentiation,biological_process
58332,GO:0001924,"Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.",regulation of B-1 B cell differentiation,biological_process
58333,GO:0001925,"Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.",negative regulation of B-1 B cell differentiation,biological_process
58334,GO:0001926,"Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.",positive regulation of B-1 B cell differentiation,biological_process
58335,GO:0001927,"The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.",exocyst assembly,biological_process
58336,GO:0001928,"Any process that modulates the frequency, rate or extent of exocyst assembly.",regulation of exocyst assembly,biological_process
58337,GO:0001929,"Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.",negative regulation of exocyst assembly,biological_process
58338,GO:0001930,Any process that increases the rate or extent of exocyst assembly.,positive regulation of exocyst assembly,biological_process
58339,GO:0001931,"A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.",uropod,cellular_component
58340,GO:0001932,"Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.",regulation of protein phosphorylation,biological_process
58341,GO:0001933,"Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.",negative regulation of protein phosphorylation,biological_process
58342,GO:0001934,"Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.",positive regulation of protein phosphorylation,biological_process
58343,GO:0001935,"The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.",endothelial cell proliferation,biological_process
58344,GO:0001936,"Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.",regulation of endothelial cell proliferation,biological_process
58345,GO:0001937,"Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.",negative regulation of endothelial cell proliferation,biological_process
58346,GO:0001938,Any process that activates or increases the rate or extent of endothelial cell proliferation.,positive regulation of endothelial cell proliferation,biological_process
58347,GO:0001939,The pronucleus originating from the ovum that is being fertilized.,female pronucleus,cellular_component
58348,GO:0001940,The pronucleus originating from the spermatozoa that was involved in fertilization.,male pronucleus,cellular_component
58349,GO:0001941,"A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).",postsynaptic membrane organization,biological_process
58350,GO:0001942,"The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.",hair follicle development,biological_process
58351,GO:0001944,"The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.",vasculature development,biological_process
58352,GO:0001945,"The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.",lymph vessel development,biological_process
58353,GO:0001946,Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.,lymphangiogenesis,biological_process
58354,GO:0001947,The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceding septation.,heart looping,biological_process
58355,GO:0001949,The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.,sebaceous gland cell differentiation,biological_process
58356,GO:0001951,Uptake of D-glucose into the blood by absorption from the small intestine.,intestinal D-glucose absorption,biological_process
58357,GO:0001952,"Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.",regulation of cell-matrix adhesion,biological_process
58358,GO:0001953,"Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.",negative regulation of cell-matrix adhesion,biological_process
58359,GO:0001954,Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.,positive regulation of cell-matrix adhesion,biological_process
58360,GO:0001955,"A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.",blood vessel maturation,biological_process
58361,GO:0001956,"Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.",positive regulation of neurotransmitter secretion,biological_process
58362,GO:0001957,Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.,intramembranous ossification,biological_process
58363,GO:0001958,Replacement ossification wherein bone tissue replaces cartilage.,endochondral ossification,biological_process
58364,GO:0001959,"Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.",regulation of cytokine-mediated signaling pathway,biological_process
58365,GO:0001960,"Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.",negative regulation of cytokine-mediated signaling pathway,biological_process
58366,GO:0001961,"Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.",positive regulation of cytokine-mediated signaling pathway,biological_process
58367,GO:0001962,"Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.","alpha-1,3-galactosyltransferase activity",molecular_function
58368,GO:0001963,"The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival ...","synaptic transmission, dopaminergic",biological_process
58369,GO:0001964,An action or movement due to the application of a sudden unexpected stimulus.,startle response,biological_process
58370,GO:0001965,Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.,G-protein alpha-subunit binding,molecular_function
58371,GO:0001966,"The directed movement of an organism along a spatial gradient of mechanical contact with solid surfaces, typically manifested as a preference for maintaining proximity to walls, edges, or boundaries.",thigmotaxis,biological_process
58372,GO:0001967,Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.,suckling behavior,biological_process
58373,GO:0001968,"Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.",fibronectin binding,molecular_function
58374,GO:0001969,"Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.",regulation of activation of membrane attack complex,biological_process
58375,GO:0001970,"Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.",positive regulation of activation of membrane attack complex,biological_process
58376,GO:0001971,"Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.",negative regulation of activation of membrane attack complex,biological_process
58377,GO:0001972,"Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.",retinoic acid binding,molecular_function
58378,GO:0001973,The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.,G protein-coupled adenosine receptor signaling pathway,biological_process
58379,GO:0001974,The reorganization or renovation of existing blood vessels.,blood vessel remodeling,biological_process
58380,GO:0001975,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.",response to amphetamine,biological_process
58381,GO:0001976,The regulation of blood pressure mediated by detection of stimuli and a neurological response.,nervous system process involved in regulation of systemic arterial blood pressure,biological_process
58382,GO:0001978,The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.,regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback,biological_process
58383,GO:0001979,"The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.",regulation of systemic arterial blood pressure by chemoreceptor signaling,biological_process
58384,GO:0001980,The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.,regulation of systemic arterial blood pressure by ischemic conditions,biological_process
58385,GO:0001981,The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.,baroreceptor detection of arterial stretch,biological_process
58386,GO:0001982,The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.,baroreceptor response to decreased systemic arterial blood pressure,biological_process
58387,GO:0001983,The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.,baroreceptor response to increased systemic arterial blood pressure,biological_process
58388,GO:0001984,"An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.",artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure,biological_process
58389,GO:0001985,"Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.",negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure,biological_process
58390,GO:0001986,Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.,negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure,biological_process
58391,GO:0001987,A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.,vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure,biological_process
58392,GO:0001988,"Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.",positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure,biological_process
58393,GO:0001990,"The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.",regulation of systemic arterial blood pressure by hormone,biological_process
58394,GO:0001991,The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.,regulation of systemic arterial blood pressure by circulatory renin-angiotensin,biological_process
58395,GO:0001992,"The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.",regulation of systemic arterial blood pressure by vasopressin,biological_process
58396,GO:0001993,The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.,regulation of systemic arterial blood pressure by norepinephrine-epinephrine,biological_process
58397,GO:0001994,A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.,norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure,biological_process
58398,GO:0001995,The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.,norepinephrine-epinephrine catabolic process in blood stream,biological_process
58399,GO:0001996,"The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.",positive regulation of heart rate by epinephrine-norepinephrine,biological_process
58400,GO:0001997,Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.,positive regulation of the force of heart contraction by epinephrine-norepinephrine,biological_process
58401,GO:0001998,The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.,angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure,biological_process
58402,GO:0001999,The physiological response of the kidneys to a decrease in blood flow.,renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure,biological_process
58403,GO:0002000,The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.,detection of renal blood flow,biological_process
58404,GO:0002001,The regulated release of renin into the blood stream by juxtoglomerular cells.,renin secretion into blood stream,biological_process
58405,GO:0002002,"The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.",regulation of angiotensin levels in blood,biological_process
58406,GO:0002003,The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.,angiotensin maturation,biological_process
58407,GO:0002007,The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.,detection of hypoxic conditions in blood by chemoreceptor signaling,biological_process
58408,GO:0002008,"The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.",excitation of vasomotor center by chemoreceptor signaling,biological_process
58409,GO:0002009,"The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.",morphogenesis of an epithelium,biological_process
58410,GO:0002010,The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.,excitation of vasomotor center by baroreceptor signaling,biological_process
58411,GO:0002011,The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.,morphogenesis of an epithelial sheet,biological_process
58412,GO:0002013,The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.,detection of carbon dioxide by vasomotor center,biological_process
58413,GO:0002014,The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.,vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure,biological_process
58414,GO:0002015,A process that controls blood pressure by sensing the amount of stretch occurring in the atria.,regulation of systemic arterial blood pressure by atrial baroreceptor feedback,biological_process
58415,GO:0002016,The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.,regulation of blood volume by renin-angiotensin,biological_process
58416,GO:0002017,The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.,regulation of blood volume by renal aldosterone,biological_process
58417,GO:0002018,The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.,renin-angiotensin regulation of aldosterone production,biological_process
58418,GO:0002019,The process in which angiotensin directly modulates the rate of urine output by the kidney.,regulation of renal output by angiotensin,biological_process
58419,GO:0002020,Binding to a protease or a peptidase.,protease binding,molecular_function
58420,GO:0002021,"The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.",response to dietary excess,biological_process
58421,GO:0002022,The neurological process in which the brain senses excessive caloric intake.,detection of dietary excess,biological_process
58422,GO:0002023,An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.,reduction of food intake in response to dietary excess,biological_process
58423,GO:0002024,The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.,diet induced thermogenesis,biological_process
58424,GO:0002025,A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.,norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure,biological_process
58425,GO:0002026,"Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.",regulation of the force of heart contraction,biological_process
58426,GO:0002027,Any process that modulates the frequency or rate of heart contraction.,regulation of heart rate,biological_process
58427,GO:0002028,"Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of sodium ion transport,biological_process
58428,GO:0002029,"The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.",desensitization of G protein-coupled receptor signaling pathway,biological_process
58429,GO:0002030,The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.,inhibitory G protein-coupled receptor phosphorylation,biological_process
58430,GO:0002031,The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.,G protein-coupled receptor internalization,biological_process
58431,GO:0002033,The process that increases the diameter of a blood vessel via the renin-angiotensin system.,angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure,biological_process
58432,GO:0002034,The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.,maintenance of blood vessel diameter homeostasis by renin-angiotensin,biological_process
58433,GO:0002035,The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.,brain renin-angiotensin system,biological_process
58434,GO:0002036,"Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.",regulation of L-glutamate import across plasma membrane,biological_process
58435,GO:0002037,"Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.",negative regulation of L-glutamate import across plasma membrane,biological_process
58436,GO:0002038,"Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.",positive regulation of L-glutamate import across plasma membrane,biological_process
58437,GO:0002039,Binding to one of the p53 family of proteins.,p53 binding,molecular_function
58438,GO:0002040,"The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.",sprouting angiogenesis,biological_process
58439,GO:0002041,The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.,intussusceptive angiogenesis,biological_process
58440,GO:0002042,The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.,cell migration involved in sprouting angiogenesis,biological_process
58441,GO:0002043,"The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.",blood vessel endothelial cell proliferation involved in sprouting angiogenesis,biological_process
58442,GO:0002044,The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.,blood vessel endothelial cell migration involved in intussusceptive angiogenesis,biological_process
58443,GO:0002046,"Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.",opsin binding,molecular_function
58444,GO:0002047,"The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.",phenazine biosynthetic process,biological_process
58445,GO:0002049,The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.,pyoverdine biosynthetic process,biological_process
58446,GO:0002050,The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.,pyoverdine catabolic process,biological_process
58447,GO:0002051,The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.,osteoblast fate commitment,biological_process
58448,GO:0002052,Any process that activates or increases the rate of neuroblast proliferation.,positive regulation of neuroblast proliferation,biological_process
58449,GO:0002053,The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.,positive regulation of mesenchymal cell proliferation,biological_process
58450,GO:0002054,"Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.",nucleobase binding,molecular_function
58451,GO:0002055,"Binding to adenine, a purine base.",adenine binding,molecular_function
58452,GO:0002056,Binding to cytosine.,cytosine binding,molecular_function
58453,GO:0002057,Binding to guanine.,guanine binding,molecular_function
58454,GO:0002058,Binding to uracil.,uracil binding,molecular_function
58455,GO:0002059,Binding to thymine.,thymine binding,molecular_function
58456,GO:0002060,"Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.",purine nucleobase binding,molecular_function
58457,GO:0002061,"Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.",pyrimidine nucleobase binding,molecular_function
58458,GO:0002062,The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.,chondrocyte differentiation,biological_process
58459,GO:0002063,"The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.",chondrocyte development,biological_process
58460,GO:0002064,"The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.",epithelial cell development,biological_process
58461,GO:0002065,The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.,columnar/cuboidal epithelial cell differentiation,biological_process
58462,GO:0002066,"The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.",columnar/cuboidal epithelial cell development,biological_process
58463,GO:0002067,The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.,glandular epithelial cell differentiation,biological_process
58464,GO:0002068,"The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.",glandular epithelial cell development,biological_process
58465,GO:0002069,"The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.",columnar/cuboidal epithelial cell maturation,biological_process
58466,GO:0002070,"The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.",epithelial cell maturation,biological_process
58467,GO:0002071,"The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.",glandular epithelial cell maturation,biological_process
58468,GO:0002072,"The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.",optic cup morphogenesis involved in camera-type eye development,biological_process
58469,GO:0002074,"The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.",extraocular skeletal muscle development,biological_process
58470,GO:0002075,"The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.",somitomeric trunk muscle development,biological_process
58471,GO:0002076,"The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.",osteoblast development,biological_process
58472,GO:0002077,"The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.",acrosome matrix dispersal,biological_process
58473,GO:0002078,The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.,membrane fusion involved in acrosome reaction,biological_process
58474,GO:0002079,The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.,inner acrosomal membrane,cellular_component
58475,GO:0002080,The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.,acrosomal membrane,cellular_component
58476,GO:0002081,The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.,outer acrosomal membrane,cellular_component
58477,GO:0002082,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.",regulation of oxidative phosphorylation,biological_process
58478,GO:0002084,The removal of palymitoyl groups from a lipoprotein.,protein depalmitoylation,biological_process
58479,GO:0002085,Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.,inhibition of neuroepithelial cell differentiation,biological_process
58480,GO:0002086,"A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.",diaphragm contraction,biological_process
58481,GO:0002087,A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.,regulation of respiratory gaseous exchange by nervous system process,biological_process
58482,GO:0002088,"The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.",lens development in camera-type eye,biological_process
58483,GO:0002089,The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.,lens morphogenesis in camera-type eye,biological_process
58484,GO:0002090,"Any process that modulates the frequency, rate or extent of receptor internalization.",regulation of receptor internalization,biological_process
58485,GO:0002091,"Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.",negative regulation of receptor internalization,biological_process
58486,GO:0002092,"Any process that activates or increases the frequency, rate or extent of receptor internalization.",positive regulation of receptor internalization,biological_process
58487,GO:0002093,Any process that alters the size or shape of an auditory receptor cell.,auditory receptor cell morphogenesis,biological_process
58488,GO:0002095,"A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).",caveolar macromolecular signaling complex,cellular_component
58489,GO:0002096,"A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.",polkadots,cellular_component
58490,GO:0002097,The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.,tRNA wobble base modification,biological_process
58491,GO:0002098,The process in which a uridine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.,tRNA wobble uridine modification,biological_process
58492,GO:0002099,The process in which a guanine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.,tRNA wobble guanine modification,biological_process
58493,GO:0002100,The process in which an adenosine at position 34 of a tRNA is post-transcriptionally converted to inosine. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.,tRNA wobble adenosine to inosine editing,biological_process
58494,GO:0002101,The process in which a cytosine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.,tRNA wobble cytosine modification,biological_process
58495,GO:0002102,"An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.",podosome,cellular_component
58496,GO:0002103,"Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced fr...","endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
58497,GO:0002104,"Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the prim...","endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
58498,GO:0002105,"Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the pri...","endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
58499,GO:0002106,"Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of matu...","endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)",biological_process
58500,GO:0002107,The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.,generation of mature 3'-end of 5S rRNA generated by RNA polymerase III,biological_process
58501,GO:0002108,"Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.","maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)",biological_process
58502,GO:0002109,"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.","maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)",biological_process
58503,GO:0002110,"The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.",cotranscriptional mitochondrial rRNA nucleotide insertion,biological_process
58504,GO:0002111,A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.,BRCA2-BRAF35 complex,cellular_component
58505,GO:0002112,Binding to an interleukin-33 receptor.,interleukin-33 receptor binding,molecular_function
58506,GO:0002113,Binding to interleukin-33.,interleukin-33 binding,molecular_function
58507,GO:0002114,Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-33 receptor activity,molecular_function
58508,GO:0002115,A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.,store-operated calcium entry,biological_process
58509,GO:0002116,"A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor.",semaphorin receptor complex,cellular_component
58510,GO:0002117,"The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.",amphibian larval development,biological_process
58511,GO:0002118,A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.,aggressive behavior,biological_process
58512,GO:0002119,"The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nemato...",nematode larval development,biological_process
58513,GO:0002121,"Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.",inter-male aggressive behavior,biological_process
58514,GO:0002122,Aggressive behavior associated with attempts to flee from a threat.,fear-induced aggressive behavior,biological_process
58515,GO:0002123,Aggressive behavior induced by frustration and directed against an available target.,irritable aggressive behavior,biological_process
58516,GO:0002124,"Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.",territorial aggressive behavior,biological_process
58517,GO:0002125,Aggressive behavior of a female to protect her offspring from a threat.,maternal aggressive behavior,biological_process
58518,GO:0002126,"Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.",instrumental aggressive behavior,biological_process
58519,GO:0002127,The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.,tRNA wobble base cytosine methylation,biological_process
58520,GO:0002128,The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.,tRNA nucleoside ribose methylation,biological_process
58521,GO:0002129,The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.,wobble position guanine ribose methylation,biological_process
58522,GO:0002130,The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.,wobble position ribose methylation,biological_process
58523,GO:0002131,The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.,wobble position cytosine ribose methylation,biological_process
58524,GO:0002132,The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.,wobble position uridine ribose methylation,biological_process
58525,GO:0002133,A stable heterodimeric complex composed of polycystin-1 and polycystin-2.,polycystin complex,cellular_component
58526,GO:0002134,"Binding to UTP, uridine 5'-triphosphate.",UTP binding,molecular_function
58527,GO:0002135,"Binding to CTP, cytidine 5'-triphosphate.",CTP binding,molecular_function
58528,GO:0002136,The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.,tRNA wobble base lysidine biosynthesis,biological_process
58529,GO:0002138,"The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.",retinoic acid biosynthetic process,biological_process
58530,GO:0002139,"A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.",stereocilia coupling link,cellular_component
58531,GO:0002140,"A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.",stereocilia tip link,cellular_component
58532,GO:0002141,A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.,stereocilia ankle link,cellular_component
58533,GO:0002142,"A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.",stereocilia ankle link complex,cellular_component
58534,GO:0002143,The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from L-cysteine to position C2 by several steps.,tRNA wobble position uridine thiolation,biological_process
58535,GO:0002144,A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.,cytosolic tRNA wobble base thiouridylase complex,cellular_component
58536,GO:0002145,Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H+.,4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity,molecular_function
58537,GO:0002151,"Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.",G-quadruplex RNA binding,molecular_function
58538,GO:0002152,The process in which bile acids are covalently linked to taurine or glycine.,bile acid conjugation,biological_process
58539,GO:0002153,Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.,steroid receptor RNA activator RNA binding,molecular_function
58540,GO:0002154,"A nuclear receptor-mediated signaling pathway initiated by a thyroid hormone  binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",thyroid hormone receptor signaling pathway,biological_process
58541,GO:0002155,"Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.",regulation of thyroid hormone receptor signaling pathway,biological_process
58542,GO:0002156,"Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.",negative regulation of thyroid hormone receptor signaling pathway,biological_process
58543,GO:0002157,"Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.",positive regulation of thyroid hormone receptor signaling pathway,biological_process
58544,GO:0002158,"The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.",osteoclast proliferation,biological_process
58545,GO:0002159,"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.",desmosome assembly,biological_process
58546,GO:0002160,"The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.",desmosome maintenance,biological_process
58547,GO:0002161,The hydrolysis of an incorrectly aminoacylated tRNA.,aminoacyl-tRNA deacylase activity,molecular_function
58548,GO:0002162,"Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).",dystroglycan binding,molecular_function
58549,GO:0002164,"The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.",larval development,biological_process
58550,GO:0002165,"The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.",instar larval or pupal development,biological_process
58551,GO:0002167,"A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.",VRK3/VHR/ERK complex,cellular_component
58552,GO:0002168,"The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.",instar larval development,biological_process
58553,GO:0002170,"Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",high-affinity IgA receptor activity,molecular_function
58554,GO:0002171,"Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",low-affinity IgA receptor activity,molecular_function
58555,GO:0002172,"Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",high-affinity IgM receptor activity,molecular_function
58556,GO:0002173,"Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",low-affinity IgM receptor activity,molecular_function
58557,GO:0002174,"The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.",mammary stem cell proliferation,biological_process
58558,GO:0002175,"A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.",protein localization to paranode region of axon,biological_process
58559,GO:0002176,"The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.",male germ cell proliferation,biological_process
58560,GO:0002177,A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.,manchette,cellular_component
58561,GO:0002178,A protein complex with palmitoyltransferase activity.,palmitoyltransferase complex,cellular_component
58562,GO:0002179,"A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.",homodimeric serine palmitoyltransferase complex,cellular_component
58563,GO:0002180,An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.,5-lipoxygenase complex,cellular_component
58564,GO:0002181,The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.,cytoplasmic translation,biological_process
58565,GO:0002182,The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.,cytoplasmic translational elongation,biological_process
58566,GO:0002183,"The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.",cytoplasmic translational initiation,biological_process
58567,GO:0002184,"The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.",cytoplasmic translational termination,biological_process
58568,GO:0002185,A protein complex having creatine kinase activity.,creatine kinase complex,cellular_component
58569,GO:0002186,A dimeric protein complex having creatine kinase activity.,cytosolic creatine kinase complex,cellular_component
58570,GO:0002187,An octomeric protein complex having creatine kinase activity.,mitochondrial creatine kinase complex,cellular_component
58571,GO:0002188,"A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.",translation reinitiation,biological_process
58572,GO:0002189,A protein complex having ribose phosphate diphosphokinase activity.,ribose phosphate diphosphokinase complex,cellular_component
58573,GO:0002190,The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.,cap-independent translational initiation,biological_process
58574,GO:0002191,"The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.",cap-dependent translational initiation,biological_process
58575,GO:0002192,The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.,IRES-dependent translational initiation of linear mRNA,biological_process
58576,GO:0002193,"A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML1-RBP-Jkappa- ICN1 complex,cellular_component
58577,GO:0002194,"The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.",hepatocyte cell migration,biological_process
58578,GO:0002196,Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).,Ser-tRNA(Ala) deacylase activity,molecular_function
58579,GO:0002197,A homodimeric protein complex having xanthine dehydrogenase activity.,xanthine dehydrogenase complex,cellular_component
58580,GO:0002199,A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.,zona pellucida receptor complex,cellular_component
58581,GO:0002200,The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.,somatic diversification of immune receptors,biological_process
58582,GO:0002201,The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.,somatic diversification of DSCAM-based immune receptors,biological_process
58583,GO:0002202,The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.,somatic diversification of variable lymphocyte receptors of jawless fish,biological_process
58584,GO:0002203,The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.,proteolysis by cytosolic proteases associated with antigen processing and presentation,biological_process
58585,GO:0002204,"The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.",somatic recombination of immunoglobulin genes involved in immune response,biological_process
58586,GO:0002206,The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.,gene conversion of immunoglobulin genes,biological_process
58587,GO:0002208,"The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.",somatic diversification of immunoglobulins involved in immune response,biological_process
58588,GO:0002209,A behavioral response seeking to protect an organism from an perceived external threat to that organism.,behavioral defense response,biological_process
58589,GO:0002210,A behavioral response resulting from wounding.,behavioral response to wounding,biological_process
58590,GO:0002211,A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.,behavioral defense response to insect,biological_process
58591,GO:0002212,A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.,behavioral defense response to nematode,biological_process
58592,GO:0002213,A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.,defense response to insect,biological_process
58593,GO:0002215,"A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.",defense response to nematode,biological_process
58594,GO:0002218,Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.,activation of innate immune response,biological_process
58595,GO:0002220,The series of molecular signals initiated by a ligand binding to a cell surface receptor that leads to the activation of an innate immune response.,innate immune response activating cell surface receptor signaling pathway,biological_process
58596,GO:0002221,"The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.",pattern recognition receptor signaling pathway,biological_process
58597,GO:0002222,The series of molecular signals initiated by a ligand binding to a killer cell immunoglobulin-like receptor capable of cellular activation.,stimulatory killer cell immunoglobulin-like receptor signaling pathway,biological_process
58598,GO:0002223,"The series of molecular signals initiated by the binding of C-type lectin to its receptor on the surface of a target cell, and resulting in cellular activation.",stimulatory C-type lectin receptor signaling pathway,biological_process
58599,GO:0002224,The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.,toll-like receptor signaling pathway,biological_process
58600,GO:0002225,"Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.",positive regulation of antimicrobial peptide production,biological_process
58601,GO:0002227,Any process of the innate immune response that takes place in the mucosal tissues.,innate immune response in mucosa,biological_process
58602,GO:0002228,The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.,natural killer cell mediated immunity,biological_process
58603,GO:0002229,Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.,defense response to oomycetes,biological_process
58604,GO:0002230,"Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.",positive regulation of defense response to virus by host,biological_process
58605,GO:0002231,The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.,detection of oomycetes,biological_process
58606,GO:0002232,The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.,leukocyte chemotaxis involved in inflammatory response,biological_process
58607,GO:0002233,The movement of an immune cell in response to an external stimulus a part of an immune response.,leukocyte chemotaxis involved in immune response,biological_process
58608,GO:0002234,The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.,detection of endoplasmic reticulum overloading,biological_process
58609,GO:0002235,The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.,detection of unfolded protein,biological_process
58610,GO:0002236,The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.,detection of misfolded protein,biological_process
58611,GO:0002237,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.",response to molecule of bacterial origin,biological_process
58612,GO:0002238,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.",response to molecule of fungal origin,biological_process
58613,GO:0002239,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.",response to oomycetes,biological_process
58614,GO:0002240,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.",response to molecule of oomycetes origin,biological_process
58615,GO:0002241,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.",response to parasitic plant,biological_process
58616,GO:0002242,Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.,defense response to parasitic plant,biological_process
58617,GO:0002243,The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.,detection of parasitic plant,biological_process
58618,GO:0002244,"The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.",hematopoietic progenitor cell differentiation,biological_process
58619,GO:0002246,The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.,wound healing involved in inflammatory response,biological_process
58620,GO:0002248,"The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared, as part of an inflammatory response.",connective tissue replacement involved in inflammatory response wound healing,biological_process
58621,GO:0002249,"Any process contributing to lymphocyte anergy, a state of functional inactivation.",lymphocyte anergy,biological_process
58622,GO:0002250,"An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).",adaptive immune response,biological_process
58623,GO:0002251,"An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.",organ or tissue specific immune response,biological_process
58624,GO:0002252,Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.,immune effector process,biological_process
58625,GO:0002253,Any process that initiates an immune response.,activation of immune response,biological_process
58626,GO:0002254,"A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.",kinin cascade,biological_process
58627,GO:0002255,"A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular...",tissue kallikrein-kinin cascade,biological_process
58628,GO:0002256,"Any process that modulates the frequency, rate, or extent of the kinin cascade.",regulation of kinin cascade,biological_process
58629,GO:0002257,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.",negative regulation of kinin cascade,biological_process
58630,GO:0002258,"Any process that activates or increases the frequency, rate, or extent of the kinin cascade.",positive regulation of kinin cascade,biological_process
58631,GO:0002260,The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.,lymphocyte homeostasis,biological_process
58632,GO:0002261,The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.,mucosal lymphocyte homeostasis,biological_process
58633,GO:0002262,The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,myeloid cell homeostasis,biological_process
58634,GO:0002263,"A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.",cell activation involved in immune response,biological_process
58635,GO:0002264,"A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.",endothelial cell activation involved in immune response,biological_process
58636,GO:0002265,"A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.",astrocyte activation involved in immune response,biological_process
58637,GO:0002266,A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.,follicular dendritic cell activation,biological_process
58638,GO:0002268,The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.,follicular dendritic cell differentiation,biological_process
58639,GO:0002269,"A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.",leukocyte activation involved in inflammatory response,biological_process
58640,GO:0002270,A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.,plasmacytoid dendritic cell activation,biological_process
58641,GO:0002273,The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.,plasmacytoid dendritic cell differentiation,biological_process
58642,GO:0002274,A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.,myeloid leukocyte activation,biological_process
58643,GO:0002275,"A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.",myeloid cell activation involved in immune response,biological_process
58644,GO:0002276,"A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.",basophil activation involved in immune response,biological_process
58645,GO:0002277,"The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",myeloid dendritic cell activation involved in immune response,biological_process
58646,GO:0002278,"The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",eosinophil activation involved in immune response,biological_process
58647,GO:0002279,"The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.",mast cell activation involved in immune response,biological_process
58648,GO:0002280,"The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",monocyte activation involved in immune response,biological_process
58649,GO:0002281,"A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",macrophage activation involved in immune response,biological_process
58650,GO:0002282,"The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",microglial cell activation involved in immune response,biological_process
58651,GO:0002283,"The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",neutrophil activation involved in immune response,biological_process
58652,GO:0002285,"A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",lymphocyte activation involved in immune response,biological_process
58653,GO:0002286,"The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.",T cell activation involved in immune response,biological_process
58654,GO:0002287,"The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.",alpha-beta T cell activation involved in immune response,biological_process
58655,GO:0002291,"The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.",T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,biological_process
58656,GO:0002292,"The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.",T cell differentiation involved in immune response,biological_process
58657,GO:0002295,"The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.",T-helper cell lineage commitment,biological_process
58658,GO:0002296,"The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.",T-helper 1 cell lineage commitment,biological_process
58659,GO:0002297,"The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.",T-helper 2 cell lineage commitment,biological_process
58660,GO:0002299,The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.,alpha-beta intraepithelial T cell differentiation,biological_process
58661,GO:0002300,"The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.","CD8-positive, alpha-beta intraepithelial T cell differentiation",biological_process
58662,GO:0002301,"The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.","CD4-positive, alpha-beta intraepithelial T cell differentiation",biological_process
58663,GO:0002302,"The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.","CD8-positive, alpha-beta T cell differentiation involved in immune response",biological_process
58664,GO:0002304,The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.,gamma-delta intraepithelial T cell differentiation,biological_process
58665,GO:0002305,"The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.","CD8-positive, gamma-delta intraepithelial T cell differentiation",biological_process
58666,GO:0002306,"The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.",CD4-positive gamma-delta intraepithelial T cell differentiation,biological_process
58667,GO:0002307,"The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.","CD8-positive, alpha-beta regulatory T cell differentiation",biological_process
58668,GO:0002308,"The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.","CD8-positive, alpha-beta cytotoxic T cell differentiation",biological_process
58669,GO:0002309,The expansion of a T cell population by cell division as part of an immune response.,T cell proliferation involved in immune response,biological_process
58670,GO:0002312,"The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",B cell activation involved in immune response,biological_process
58671,GO:0002313,The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.,mature B cell differentiation involved in immune response,biological_process
58672,GO:0002314,The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).,germinal center B cell differentiation,biological_process
58673,GO:0002315,"The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).",marginal zone B cell differentiation,biological_process
58674,GO:0002316,The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.,follicular B cell differentiation,biological_process
58675,GO:0002317,The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.,plasma cell differentiation,biological_process
58676,GO:0002318,The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.,myeloid progenitor cell differentiation,biological_process
58677,GO:0002319,The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.,memory B cell differentiation,biological_process
58678,GO:0002320,The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.,lymphoid progenitor cell differentiation,biological_process
58679,GO:0002321,The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.,natural killer cell progenitor differentiation,biological_process
58680,GO:0002322,The expansion of a B cell population by cell division following B cell activation during an immune response.,B cell proliferation involved in immune response,biological_process
58681,GO:0002323,"The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",natural killer cell activation involved in immune response,biological_process
58682,GO:0002326,The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.,B cell lineage commitment,biological_process
58683,GO:0002327,The process in which a precursor cell type acquires the specialized features of an immature B cell.,immature B cell differentiation,biological_process
58684,GO:0002328,"The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.",pro-B cell differentiation,biological_process
58685,GO:0002329,"The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.",pre-B cell differentiation,biological_process
58686,GO:0002330,"The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.",pre-B cell receptor expression,biological_process
58687,GO:0002331,Expression of a single heavy chain allele during pre-B cell differentiation.,pre-B cell allelic exclusion,biological_process
58688,GO:0002332,The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.,transitional stage B cell differentiation,biological_process
58689,GO:0002333,The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.,transitional one stage B cell differentiation,biological_process
58690,GO:0002334,The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.,transitional two stage B cell differentiation,biological_process
58691,GO:0002335,The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.,mature B cell differentiation,biological_process
58692,GO:0002336,The process in which an immature B cell becomes committed to become a B-1 B cell.,B-1 B cell lineage commitment,biological_process
58693,GO:0002337,The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.,B-1a B cell differentiation,biological_process
58694,GO:0002338,The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.,B-1b B cell differentiation,biological_process
58695,GO:0002339,The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.,B cell selection,biological_process
58696,GO:0002340,Any B cell selection process that occurs in the bone marrow.,central B cell selection,biological_process
58697,GO:0002341,"Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.",central B cell anergy,biological_process
58698,GO:0002342,The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.,central B cell deletion,biological_process
58699,GO:0002343,Any B cell selection process that occurs in the periphery.,peripheral B cell selection,biological_process
58700,GO:0002344,The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.,B cell affinity maturation,biological_process
58701,GO:0002345,The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.,peripheral B cell receptor editing,biological_process
58702,GO:0002346,Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.,B cell positive selection,biological_process
58703,GO:0002347,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.",response to tumor cell,biological_process
58704,GO:0002348,Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.,central B cell positive selection,biological_process
58705,GO:0002349,"The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",histamine production involved in inflammatory response,biological_process
58706,GO:0002350,Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.,peripheral B cell positive selection,biological_process
58707,GO:0002351,"The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",serotonin production involved in inflammatory response,biological_process
58708,GO:0002352,Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.,B cell negative selection,biological_process
58709,GO:0002353,"A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular perme...",plasma kallikrein-kinin cascade,biological_process
58710,GO:0002354,Any process leading to negative selection of B cells in the bone marrow.,central B cell negative selection,biological_process
58711,GO:0002355,The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.,detection of tumor cell,biological_process
58712,GO:0002356,Any process leading to negative selection of B cells in the periphery.,peripheral B cell negative selection,biological_process
58713,GO:0002357,Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.,defense response to tumor cell,biological_process
58714,GO:0002358,The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.,B cell homeostatic proliferation,biological_process
58715,GO:0002359,The expansion of a B-1 B cell by cell division. Follows B cell activation.,B-1 B cell proliferation,biological_process
58716,GO:0002360,The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.,T cell lineage commitment,biological_process
58717,GO:0002361,"The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.","CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation",biological_process
58718,GO:0002362,"The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.","CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment",biological_process
58719,GO:0002363,The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.,alpha-beta T cell lineage commitment,biological_process
58720,GO:0002364,The process in which a pro-T cell becomes committed to becoming an NK T cell.,NK T cell lineage commitment,biological_process
58721,GO:0002365,The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.,gamma-delta T cell lineage commitment,biological_process
58722,GO:0002366,"A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.",leukocyte activation involved in immune response,biological_process
58723,GO:0002367,"The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.",cytokine production involved in immune response,biological_process
58724,GO:0002368,Any process that contributes to cytokine production by a B cell.,B cell cytokine production,biological_process
58725,GO:0002369,Any process that contributes to cytokine production by a T cell.,T cell cytokine production,biological_process
58726,GO:0002370,Any process that contributes to cytokine production by a natural killer cell.,natural killer cell cytokine production,biological_process
58727,GO:0002371,Any process that contributes to cytokine production by a dendritic cell.,dendritic cell cytokine production,biological_process
58728,GO:0002372,Any process that contributes to cytokine production by a myeloid dendritic cell.,myeloid dendritic cell cytokine production,biological_process
58729,GO:0002373,Any process that contributes to cytokine production by a plasmacytoid dendritic cell.,plasmacytoid dendritic cell cytokine production,biological_process
58730,GO:0002376,"Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.",immune system process,biological_process
58731,GO:0002377,"The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",immunoglobulin production,biological_process
58732,GO:0002381,"The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.",immunoglobulin production involved in immunoglobulin-mediated immune response,biological_process
58733,GO:0002382,"Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.",regulation of tissue kallikrein-kinin cascade,biological_process
58734,GO:0002383,An immune response taking place in the brain or nervous system.,immune response in brain or nervous system,biological_process
58735,GO:0002384,An immune response taking place in the liver.,hepatic immune response,biological_process
58736,GO:0002385,"An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.",mucosal immune response,biological_process
58737,GO:0002387,"Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.",immune response in gut-associated lymphoid tissue,biological_process
58738,GO:0002388,"Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.",immune response in Peyer's patch,biological_process
58739,GO:0002389,Tolerance induction taking place in the Peyer's patches.,tolerance induction in Peyer's patch,biological_process
58740,GO:0002394,Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).,tolerance induction in gut-associated lymphoid tissue,biological_process
58741,GO:0002395,An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.,immune response in nasopharyngeal-associated lymphoid tissue,biological_process
58742,GO:0002396,"The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.",MHC protein complex assembly,biological_process
58743,GO:0002397,"The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.",MHC class I protein complex assembly,biological_process
58744,GO:0002398,"The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.",MHC class Ib protein complex assembly,biological_process
58745,GO:0002399,"The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.",MHC class II protein complex assembly,biological_process
58746,GO:0002400,Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT).,tolerance induction in nasopharyngeal-associated lymphoid tissue,biological_process
58747,GO:0002401,Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).,tolerance induction in mucosal-associated lymphoid tissue,biological_process
58748,GO:0002402,Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.,B cell tolerance induction in mucosal-associated lymphoid tissue,biological_process
58749,GO:0002403,Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.,T cell tolerance induction in mucosal-associated lymphoid tissue,biological_process
58750,GO:0002404,The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.,antigen sampling in mucosal-associated lymphoid tissue,biological_process
58751,GO:0002405,The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.,antigen sampling by dendritic cells in mucosal-associated lymphoid tissue,biological_process
58752,GO:0002406,The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.,antigen sampling by M cells in mucosal-associated lymphoid tissue,biological_process
58753,GO:0002407,The movement of a dendritic cell in response to an external stimulus.,dendritic cell chemotaxis,biological_process
58754,GO:0002408,The movement of a myeloid dendritic cell in response to an external stimulus.,myeloid dendritic cell chemotaxis,biological_process
58755,GO:0002409,The movement of a Langerhans cell in response to an external stimulus.,Langerhans cell chemotaxis,biological_process
58756,GO:0002410,The movement of a plasmacytoid dendritic cell in response to an external stimulus.,plasmacytoid dendritic cell chemotaxis,biological_process
58757,GO:0002411,A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.,T cell tolerance induction to tumor cell,biological_process
58758,GO:0002412,The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.,antigen transcytosis by M cells in mucosal-associated lymphoid tissue,biological_process
58759,GO:0002413,A process of tolerance induction which leads to immunological tolerance of a tumor.,tolerance induction to tumor cell,biological_process
58760,GO:0002414,"The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.",immunoglobulin transcytosis in epithelial cells,biological_process
58761,GO:0002415,"The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.",immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor,biological_process
58762,GO:0002416,"The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in ad...",IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor,biological_process
58763,GO:0002417,B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.,B cell antigen processing and presentation mediated by B cell receptor uptake of antigen,biological_process
58764,GO:0002418,An immune system process that functions in the response of an organism to a tumor cell.,immune response to tumor cell,biological_process
58765,GO:0002419,The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,T cell mediated cytotoxicity directed against tumor cell target,biological_process
58766,GO:0002420,The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,natural killer cell mediated cytotoxicity directed against tumor cell target,biological_process
58767,GO:0002421,B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.,B cell antigen processing and presentation following pinocytosis,biological_process
58768,GO:0002423,An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.,natural killer cell mediated immune response to tumor cell,biological_process
58769,GO:0002424,An immune response mediated by a T cell triggered in response to the presence of a tumor cell.,T cell mediated immune response to tumor cell,biological_process
58770,GO:0002425,Tolerance induction taking place in the urogenital tract.,tolerance induction in urogenital tract,biological_process
58771,GO:0002426,The synthesis and release of immunoglobulin in the mucosal tissue.,immunoglobulin production in mucosal tissue,biological_process
58772,GO:0002427,Tolerance induction taking place in the mucosal tissues.,mucosal tolerance induction,biological_process
58773,GO:0002428,"The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.",antigen processing and presentation of peptide antigen via MHC class Ib,biological_process
58774,GO:0002429,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.",immune response-activating cell surface receptor signaling pathway,biological_process
58775,GO:0002430,The series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.,complement receptor mediated signaling pathway,biological_process
58776,GO:0002431,The series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.,Fc receptor mediated stimulatory signaling pathway,biological_process
58777,GO:0002432,"The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.",granuloma formation,biological_process
58778,GO:0002434,"A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.",immune complex clearance,biological_process
58779,GO:0002435,"The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.",immune complex clearance by erythrocytes,biological_process
58780,GO:0002436,The process of immune complex clearance by monocytes or macrophages.,immune complex clearance by monocytes and macrophages,biological_process
58781,GO:0002437,"An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.",inflammatory response to antigenic stimulus,biological_process
58782,GO:0002438,"An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.",acute inflammatory response to antigenic stimulus,biological_process
58783,GO:0002439,"A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.",chronic inflammatory response to antigenic stimulus,biological_process
58784,GO:0002440,"The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.",production of molecular mediator of immune response,biological_process
58785,GO:0002441,The regulated release of histamine by a cell as part of an inflammatory response.,histamine secretion involved in inflammatory response,biological_process
58786,GO:0002442,The regulated release of serotonin by a cell as part of an inflammatory response.,serotonin secretion involved in inflammatory response,biological_process
58787,GO:0002443,Any process involved in the carrying out of an immune response by a leukocyte.,leukocyte mediated immunity,biological_process
58788,GO:0002444,Any process involved in the carrying out of an immune response by a myeloid leukocyte.,myeloid leukocyte mediated immunity,biological_process
58789,GO:0002445,"An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.",type II hypersensitivity,biological_process
58790,GO:0002446,Any process involved in the carrying out of an immune response by a neutrophil.,neutrophil mediated immunity,biological_process
58791,GO:0002447,Any process involved in the carrying out of an immune response by an eosinophil.,eosinophil mediated immunity,biological_process
58792,GO:0002448,Any process involved in the carrying out of an immune response by a mast cell.,mast cell mediated immunity,biological_process
58793,GO:0002449,Any process involved in the carrying out of an immune response by a lymphocyte.,lymphocyte mediated immunity,biological_process
58794,GO:0002450,The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,B cell antigen processing and presentation,biological_process
58795,GO:0002451,"Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.",peripheral B cell tolerance induction,biological_process
58796,GO:0002452,"The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.",B cell receptor editing,biological_process
58797,GO:0002453,"Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.",peripheral B cell anergy,biological_process
58798,GO:0002454,The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.,peripheral B cell deletion,biological_process
58799,GO:0002455,An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.,humoral immune response mediated by circulating immunoglobulin,biological_process
58800,GO:0002456,Any process involved in the carrying out of an immune response by a T cell.,T cell mediated immunity,biological_process
58801,GO:0002457,The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,T cell antigen processing and presentation,biological_process
58802,GO:0002458,"Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.",peripheral T cell tolerance induction,biological_process
58803,GO:0002459,"An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).",adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains,biological_process
58804,GO:0002460,An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great...,adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains,biological_process
58805,GO:0002461,"Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.",tolerance induction dependent upon immune response,biological_process
58806,GO:0002462,Tolerance induction in response to nonself antigens.,tolerance induction to nonself antigen,biological_process
58807,GO:0002463,Tolerance induction to nonself antigens in the central lymphoid organs.,central tolerance induction to nonself antigen,biological_process
58808,GO:0002464,Tolerance induction to nonself antigens in the periphery.,peripheral tolerance induction to nonself antigen,biological_process
58809,GO:0002465,"Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.",peripheral tolerance induction,biological_process
58810,GO:0002466,"Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.",peripheral tolerance induction to self antigen,biological_process
58811,GO:0002467,The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.,germinal center formation,biological_process
58812,GO:0002468,The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,dendritic cell antigen processing and presentation,biological_process
58813,GO:0002469,The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,myeloid dendritic cell antigen processing and presentation,biological_process
58814,GO:0002470,The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,plasmacytoid dendritic cell antigen processing and presentation,biological_process
58815,GO:0002471,The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,monocyte antigen processing and presentation,biological_process
58816,GO:0002472,The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,macrophage antigen processing and presentation,biological_process
58817,GO:0002473,"The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.",non-professional antigen presenting cell antigen processing and presentation,biological_process
58818,GO:0002474,The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.,antigen processing and presentation of peptide antigen via MHC class I,biological_process
58819,GO:0002475,"The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.",antigen processing and presentation via MHC class Ib,biological_process
58820,GO:0002476,"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.",antigen processing and presentation of endogenous peptide antigen via MHC class Ib,biological_process
58821,GO:0002477,"The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.",antigen processing and presentation of exogenous peptide antigen via MHC class Ib,biological_process
58822,GO:0002478,The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.,antigen processing and presentation of exogenous peptide antigen,biological_process
58823,GO:0002479,The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refer...,"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",biological_process
58824,GO:0002480,The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.,"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent",biological_process
58825,GO:0002481,The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here re...,"antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent",biological_process
58826,GO:0002482,"The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.","antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent",biological_process
58827,GO:0002483,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.,antigen processing and presentation of endogenous peptide antigen,biological_process
58828,GO:0002484,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.,antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway,biological_process
58829,GO:0002485,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I ...,"antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent",biological_process
58830,GO:0002486,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to ...,"antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent",biological_process
58831,GO:0002487,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.,antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway,biological_process
58832,GO:0002488,"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.",antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway,biological_process
58833,GO:0002489,The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here ...,"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent",biological_process
58834,GO:0002490,"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.","antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent",biological_process
58835,GO:0002491,"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.",antigen processing and presentation of endogenous peptide antigen via MHC class II,biological_process
58836,GO:0002492,"The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.",peptide antigen assembly with MHC class Ib protein complex,biological_process
58837,GO:0002493,"The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.",lipid antigen assembly with MHC class Ib protein complex,biological_process
58838,GO:0002494,"The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lipid antigen transport,biological_process
58839,GO:0002495,"The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.",antigen processing and presentation of peptide antigen via MHC class II,biological_process
58840,GO:0002496,The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.,proteolysis associated with antigen processing and presentation,biological_process
58841,GO:0002497,The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.,proteasomal proteolysis associated with antigen processing and presentation,biological_process
58842,GO:0002498,The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.,proteolysis within endoplasmic reticulum associated with antigen processing and presentation,biological_process
58843,GO:0002499,The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.,proteolysis within endosome associated with antigen processing and presentation,biological_process
58844,GO:0002500,The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.,proteolysis within lysosome associated with antigen processing and presentation,biological_process
58845,GO:0002501,The binding of a peptide to the antigen binding groove of an MHC protein complex.,peptide antigen assembly with MHC protein complex,biological_process
58846,GO:0002502,The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.,peptide antigen assembly with MHC class I protein complex,biological_process
58847,GO:0002503,The binding of a peptide to the antigen binding groove of an MHC class II protein complex.,peptide antigen assembly with MHC class II protein complex,biological_process
58848,GO:0002504,The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.,antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,biological_process
58849,GO:0002505,The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.,antigen processing and presentation of polysaccharide antigen via MHC class II,biological_process
58850,GO:0002507,"A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.",tolerance induction,biological_process
58851,GO:0002508,Tolerance induction in the central lymphoid organs: the thymus and bone marrow.,central tolerance induction,biological_process
58852,GO:0002509,Tolerance induction in the central lymphoid organs directed at self antigens.,central tolerance induction to self antigen,biological_process
58853,GO:0002510,Tolerance induction of B cells in the bone marrow.,central B cell tolerance induction,biological_process
58854,GO:0002511,Receptor editing occurring in B cells in the bone marrow.,central B cell receptor editing,biological_process
58855,GO:0002512,Tolerance induction of T cells in the thymus.,central T cell tolerance induction,biological_process
58856,GO:0002513,Tolerance induction directed at self antigens.,tolerance induction to self antigen,biological_process
58857,GO:0002514,A process involving any mechanism for tolerance induction in B cells.,B cell tolerance induction,biological_process
58858,GO:0002515,"Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.",B cell anergy,biological_process
58859,GO:0002516,The apoptotic death of B cells which is part of B cell tolerance induction.,B cell deletion,biological_process
58860,GO:0002517,A process involving any mechanism for tolerance induction in T cells.,T cell tolerance induction,biological_process
58861,GO:0002518,The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.,lymphocyte chemotaxis across high endothelial venule,biological_process
58862,GO:0002519,Tolerance induction of natural killer cells.,natural killer cell tolerance induction,biological_process
58863,GO:0002520,"The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.",immune system development,biological_process
58864,GO:0002521,"The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.",leukocyte differentiation,biological_process
58865,GO:0002522,The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.,leukocyte migration involved in immune response,biological_process
58866,GO:0002523,The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.,leukocyte migration involved in inflammatory response,biological_process
58867,GO:0002524,An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.,hypersensitivity,biological_process
58868,GO:0002525,An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.,acute inflammatory response to non-antigenic stimulus,biological_process
58869,GO:0002526,"Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.",acute inflammatory response,biological_process
58870,GO:0002528,Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.,regulation of vascular permeability involved in acute inflammatory response,biological_process
58871,GO:0002529,"Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.",regulation of plasma kallikrein-kinin cascade,biological_process
58872,GO:0002532,"The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.",production of molecular mediator involved in inflammatory response,biological_process
58873,GO:0002534,"The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",cytokine production involved in inflammatory response,biological_process
58874,GO:0002536,"A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.",respiratory burst involved in inflammatory response,biological_process
58875,GO:0002537,"The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",nitric oxide production involved in inflammatory response,biological_process
58876,GO:0002538,"The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.",arachidonate metabolite production involved in inflammatory response,biological_process
58877,GO:0002539,"The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",prostaglandin production involved in inflammatory response,biological_process
58878,GO:0002540,"The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",leukotriene production involved in inflammatory response,biological_process
58879,GO:0002541,Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.,activation of plasma proteins involved in acute inflammatory response,biological_process
58880,GO:0002542,"Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the cl...",Factor XII activation,biological_process
58881,GO:0002543,"Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.",activation of blood coagulation via clotting cascade,biological_process
58882,GO:0002544,"Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.",chronic inflammatory response,biological_process
58883,GO:0002545,A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.,chronic inflammatory response to non-antigenic stimulus,biological_process
58884,GO:0002546,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade.",negative regulation of tissue kallikrein-kinin cascade,biological_process
58885,GO:0002547,"Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.",positive regulation of tissue kallikrein-kinin cascade,biological_process
58886,GO:0002548,The movement of a monocyte in response to an external stimulus.,monocyte chemotaxis,biological_process
58887,GO:0002549,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.",negative regulation of plasma kallikrein-kinin cascade,biological_process
58888,GO:0002550,"Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.",positive regulation of plasma kallikrein-kinin cascade,biological_process
58889,GO:0002551,The movement of a mast cell in response to an external stimulus.,mast cell chemotaxis,biological_process
58890,GO:0002552,The regulated release of serotonin by a mast cell or group of mast cells.,serotonin secretion by mast cell,biological_process
58891,GO:0002553,The regulated release of histamine by a mast cell or group of mast cells.,histamine secretion by mast cell,biological_process
58892,GO:0002554,The regulated release of serotonin by a platelet or group of platelets.,serotonin secretion by platelet,biological_process
58893,GO:0002555,The regulated release of histamine by a platelet or group of platelets.,histamine secretion by platelet,biological_process
58894,GO:0002556,The regulated release of serotonin by a basophil or group of basophils.,serotonin secretion by basophil,biological_process
58895,GO:0002557,The regulated release of histamine by a basophil or group of basophils.,histamine secretion by basophil,biological_process
58896,GO:0002558,"An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.",type I hypersensitivity mediated by mast cells,biological_process
58897,GO:0002559,"An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.",type I hypersensitivity mediated by basophils,biological_process
58898,GO:0002560,Any process involved in the carrying out of an immune response by a basophil.,basophil mediated immunity,biological_process
58899,GO:0002561,"The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.",basophil degranulation,biological_process
58900,GO:0002562,The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.,somatic diversification of immune receptors via germline recombination within a single locus,biological_process
58901,GO:0002563,The process in which immune receptor genes are diversified through alternate splicing.,somatic diversification of immune receptors via alternate splicing,biological_process
58902,GO:0002564,The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.,alternate splicing of immunoglobulin genes,biological_process
58903,GO:0002565,The process in which immune receptor genes are diversified through gene conversion.,somatic diversification of immune receptors via gene conversion,biological_process
58904,GO:0002566,The process in which immune receptor genes are diversified through somatic mutation.,somatic diversification of immune receptors via somatic mutation,biological_process
58905,GO:0002567,The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.,somatic diversification of FREP-based immune receptors,biological_process
58906,GO:0002568,The somatic process that results in the generation of sequence diversity of T cell receptor genes.,somatic diversification of T cell receptor genes,biological_process
58907,GO:0002569,"The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.",somatic diversification of immune receptors by N region addition,biological_process
58908,GO:0002570,The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.,somatic diversification of immunoglobulin genes by N region addition,biological_process
58909,GO:0002571,"The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.",somatic diversification of T cell receptor genes by N region addition,biological_process
58910,GO:0002572,The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.,pro-T cell differentiation,biological_process
58911,GO:0002573,The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.,myeloid leukocyte differentiation,biological_process
58912,GO:0002574,"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.",thrombocyte differentiation,biological_process
58913,GO:0002575,The movement of a basophil in response to an external stimulus.,basophil chemotaxis,biological_process
58914,GO:0002576,The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.,platelet degranulation,biological_process
58915,GO:0002577,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation.",regulation of antigen processing and presentation,biological_process
58916,GO:0002578,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.",negative regulation of antigen processing and presentation,biological_process
58917,GO:0002579,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.",positive regulation of antigen processing and presentation,biological_process
58918,GO:0002580,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.",regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,biological_process
58919,GO:0002581,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.",negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,biological_process
58920,GO:0002582,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.",positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,biological_process
58921,GO:0002583,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.",regulation of antigen processing and presentation of peptide antigen,biological_process
58922,GO:0002584,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.",negative regulation of antigen processing and presentation of peptide antigen,biological_process
58923,GO:0002585,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.",positive regulation of antigen processing and presentation of peptide antigen,biological_process
58924,GO:0002586,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.",regulation of antigen processing and presentation of peptide antigen via MHC class II,biological_process
58925,GO:0002587,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.",negative regulation of antigen processing and presentation of peptide antigen via MHC class II,biological_process
58926,GO:0002588,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.",positive regulation of antigen processing and presentation of peptide antigen via MHC class II,biological_process
58927,GO:0002589,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.",regulation of antigen processing and presentation of peptide antigen via MHC class I,biological_process
58928,GO:0002590,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.",negative regulation of antigen processing and presentation of peptide antigen via MHC class I,biological_process
58929,GO:0002591,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.",positive regulation of antigen processing and presentation of peptide antigen via MHC class I,biological_process
58930,GO:0002592,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.",regulation of antigen processing and presentation via MHC class Ib,biological_process
58931,GO:0002593,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.",negative regulation of antigen processing and presentation via MHC class Ib,biological_process
58932,GO:0002594,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.",positive regulation of antigen processing and presentation via MHC class Ib,biological_process
58933,GO:0002595,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.",regulation of antigen processing and presentation of peptide antigen via MHC class Ib,biological_process
58934,GO:0002596,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.",negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib,biological_process
58935,GO:0002597,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.",positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib,biological_process
58936,GO:0002598,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.",regulation of antigen processing and presentation of lipid antigen via MHC class Ib,biological_process
58937,GO:0002599,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.",negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib,biological_process
58938,GO:0002600,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.",positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib,biological_process
58939,GO:0002601,"Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.",regulation of antigen processing and presentation of polysaccharide antigen via MHC class II,biological_process
58940,GO:0002602,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.",negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II,biological_process
58941,GO:0002603,"Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.",positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II,biological_process
58942,GO:0002604,"Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.",regulation of dendritic cell antigen processing and presentation,biological_process
58943,GO:0002605,"Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.",negative regulation of dendritic cell antigen processing and presentation,biological_process
58944,GO:0002606,"Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.",positive regulation of dendritic cell antigen processing and presentation,biological_process
58945,GO:0002607,"Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.",regulation of myeloid dendritic cell antigen processing and presentation,biological_process
58946,GO:0002608,"Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.",negative regulation of myeloid dendritic cell antigen processing and presentation,biological_process
58947,GO:0002609,"Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.",positive regulation of myeloid dendritic cell antigen processing and presentation,biological_process
58948,GO:0002610,"Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.",regulation of plasmacytoid dendritic cell antigen processing and presentation,biological_process
58949,GO:0002611,"Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.",negative regulation of plasmacytoid dendritic cell antigen processing and presentation,biological_process
58950,GO:0002612,"Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.",positive regulation of plasmacytoid dendritic cell antigen processing and presentation,biological_process
58951,GO:0002613,"Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.",regulation of monocyte antigen processing and presentation,biological_process
58952,GO:0002614,"Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.",negative regulation of monocyte antigen processing and presentation,biological_process
58953,GO:0002615,"Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.",positive regulation of monocyte antigen processing and presentation,biological_process
58954,GO:0002616,"Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.",regulation of macrophage antigen processing and presentation,biological_process
58955,GO:0002617,"Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.",negative regulation of macrophage antigen processing and presentation,biological_process
58956,GO:0002618,"Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.",positive regulation of macrophage antigen processing and presentation,biological_process
58957,GO:0002619,"Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.",regulation of non-professional antigen presenting cell antigen processing and presentation,biological_process
58958,GO:0002620,"Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.",negative regulation of non-professional antigen presenting cell antigen processing and presentation,biological_process
58959,GO:0002621,"Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.",positive regulation of non-professional antigen presenting cell antigen processing and presentation,biological_process
58960,GO:0002622,"Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.",regulation of B cell antigen processing and presentation,biological_process
58961,GO:0002623,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.",negative regulation of B cell antigen processing and presentation,biological_process
58962,GO:0002624,"Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.",positive regulation of B cell antigen processing and presentation,biological_process
58963,GO:0002625,"Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.",regulation of T cell antigen processing and presentation,biological_process
58964,GO:0002626,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.",negative regulation of T cell antigen processing and presentation,biological_process
58965,GO:0002627,"Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.",positive regulation of T cell antigen processing and presentation,biological_process
58966,GO:0002628,"Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.",regulation of proteolysis associated with antigen processing and presentation,biological_process
58967,GO:0002629,"Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.",negative regulation of proteolysis associated with antigen processing and presentation,biological_process
58968,GO:0002630,"Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.",positive regulation of proteolysis associated with antigen processing and presentation,biological_process
58969,GO:0002631,"Any process that modulates the frequency, rate, or extent of granuloma formation.",regulation of granuloma formation,biological_process
58970,GO:0002632,"Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.",negative regulation of granuloma formation,biological_process
58971,GO:0002633,"Any process that activates or increases the frequency, rate, or extent of granuloma formation.",positive regulation of granuloma formation,biological_process
58972,GO:0002634,"Any process that modulates the frequency, rate, or extent of germinal center formation.",regulation of germinal center formation,biological_process
58973,GO:0002635,"Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.",negative regulation of germinal center formation,biological_process
58974,GO:0002636,"Any process that activates or increases the frequency, rate, or extent of germinal center formation.",positive regulation of germinal center formation,biological_process
58975,GO:0002637,"Any process that modulates the frequency, rate, or extent of immunoglobulin production.",regulation of immunoglobulin production,biological_process
58976,GO:0002638,"Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.",negative regulation of immunoglobulin production,biological_process
58977,GO:0002639,"Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.",positive regulation of immunoglobulin production,biological_process
58978,GO:0002643,"Any process that modulates the frequency, rate, or extent of tolerance induction.",regulation of tolerance induction,biological_process
58979,GO:0002644,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.",negative regulation of tolerance induction,biological_process
58980,GO:0002645,"Any process that activates or increases the frequency, rate, or extent of tolerance induction.",positive regulation of tolerance induction,biological_process
58981,GO:0002646,"Any process that modulates the frequency, rate, or extent of central tolerance induction.",regulation of central tolerance induction,biological_process
58982,GO:0002647,"Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.",negative regulation of central tolerance induction,biological_process
58983,GO:0002648,"Any process that activates or increases the frequency, rate, or extent of central tolerance induction.",positive regulation of central tolerance induction,biological_process
58984,GO:0002649,"Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.",regulation of tolerance induction to self antigen,biological_process
58985,GO:0002650,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.",negative regulation of tolerance induction to self antigen,biological_process
58986,GO:0002651,"Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.",positive regulation of tolerance induction to self antigen,biological_process
58987,GO:0002652,"Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.",regulation of tolerance induction dependent upon immune response,biological_process
58988,GO:0002653,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.",negative regulation of tolerance induction dependent upon immune response,biological_process
58989,GO:0002654,"Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.",positive regulation of tolerance induction dependent upon immune response,biological_process
58990,GO:0002655,"Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.",regulation of tolerance induction to nonself antigen,biological_process
58991,GO:0002656,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.",negative regulation of tolerance induction to nonself antigen,biological_process
58992,GO:0002657,"Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.",positive regulation of tolerance induction to nonself antigen,biological_process
58993,GO:0002658,"Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.",regulation of peripheral tolerance induction,biological_process
58994,GO:0002659,"Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.",negative regulation of peripheral tolerance induction,biological_process
58995,GO:0002660,"Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.",positive regulation of peripheral tolerance induction,biological_process
58996,GO:0002661,"Any process that modulates the frequency, rate, or extent of B cell tolerance induction.",regulation of B cell tolerance induction,biological_process
58997,GO:0002662,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.",negative regulation of B cell tolerance induction,biological_process
58998,GO:0002663,"Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.",positive regulation of B cell tolerance induction,biological_process
58999,GO:0002664,"Any process that modulates the frequency, rate, or extent of T cell tolerance induction.",regulation of T cell tolerance induction,biological_process
59000,GO:0002665,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.",negative regulation of T cell tolerance induction,biological_process
59001,GO:0002666,"Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.",positive regulation of T cell tolerance induction,biological_process
59002,GO:0002667,"Any process that modulates the frequency, rate, or extent of T cell anergy.",regulation of T cell anergy,biological_process
59003,GO:0002668,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.",negative regulation of T cell anergy,biological_process
59004,GO:0002669,"Any process that activates or increases the frequency, rate, or extent of T cell anergy.",positive regulation of T cell anergy,biological_process
59005,GO:0002670,"Any process that modulates the frequency, rate, or extent of B cell anergy.",regulation of B cell anergy,biological_process
59006,GO:0002671,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.",negative regulation of B cell anergy,biological_process
59007,GO:0002672,"Any process that activates or increases the frequency, rate, or extent of B cell anergy.",positive regulation of B cell anergy,biological_process
59008,GO:0002673,"Any process that modulates the frequency, rate, or extent of an acute inflammatory response.",regulation of acute inflammatory response,biological_process
59009,GO:0002674,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.",negative regulation of acute inflammatory response,biological_process
59010,GO:0002675,"Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.",positive regulation of acute inflammatory response,biological_process
59011,GO:0002676,"Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.",regulation of chronic inflammatory response,biological_process
59012,GO:0002677,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.",negative regulation of chronic inflammatory response,biological_process
59013,GO:0002678,"Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.",positive regulation of chronic inflammatory response,biological_process
59014,GO:0002679,"A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",respiratory burst involved in defense response,biological_process
59015,GO:0002680,The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.,pro-T cell lineage commitment,biological_process
59016,GO:0002681,"The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.",somatic recombination of T cell receptor gene segments,biological_process
59017,GO:0002682,"Any process that modulates the frequency, rate, or extent of an immune system process.",regulation of immune system process,biological_process
59018,GO:0002683,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.",negative regulation of immune system process,biological_process
59019,GO:0002684,"Any process that activates or increases the frequency, rate, or extent of an immune system process.",positive regulation of immune system process,biological_process
59020,GO:0002685,"Any process that modulates the frequency, rate, or extent of leukocyte migration.",regulation of leukocyte migration,biological_process
59021,GO:0002686,"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.",negative regulation of leukocyte migration,biological_process
59022,GO:0002687,"Any process that activates or increases the frequency, rate, or extent of leukocyte migration.",positive regulation of leukocyte migration,biological_process
59023,GO:0002688,"Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.",regulation of leukocyte chemotaxis,biological_process
59024,GO:0002689,"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.",negative regulation of leukocyte chemotaxis,biological_process
59025,GO:0002690,"Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.",positive regulation of leukocyte chemotaxis,biological_process
59026,GO:0002691,"Any process that modulates the frequency, rate, or extent of cellular extravasation.",regulation of cellular extravasation,biological_process
59027,GO:0002692,"Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.",negative regulation of cellular extravasation,biological_process
59028,GO:0002693,"Any process that activates or increases the frequency, rate, or extent of cellular extravasation.",positive regulation of cellular extravasation,biological_process
59029,GO:0002694,"Any process that modulates the frequency, rate, or extent of leukocyte activation.",regulation of leukocyte activation,biological_process
59030,GO:0002695,"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.",negative regulation of leukocyte activation,biological_process
59031,GO:0002696,"Any process that activates or increases the frequency, rate, or extent of leukocyte activation.",positive regulation of leukocyte activation,biological_process
59032,GO:0002697,"Any process that modulates the frequency, rate, or extent of an immune effector process.",regulation of immune effector process,biological_process
59033,GO:0002698,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.",negative regulation of immune effector process,biological_process
59034,GO:0002699,"Any process that activates or increases the frequency, rate, or extent of an immune effector process.",positive regulation of immune effector process,biological_process
59035,GO:0002700,"Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.",regulation of production of molecular mediator of immune response,biological_process
59036,GO:0002701,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.",negative regulation of production of molecular mediator of immune response,biological_process
59037,GO:0002702,"Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.",positive regulation of production of molecular mediator of immune response,biological_process
59038,GO:0002703,"Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.",regulation of leukocyte mediated immunity,biological_process
59039,GO:0002704,"Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.",negative regulation of leukocyte mediated immunity,biological_process
59040,GO:0002705,"Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.",positive regulation of leukocyte mediated immunity,biological_process
59041,GO:0002706,"Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.",regulation of lymphocyte mediated immunity,biological_process
59042,GO:0002707,"Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.",negative regulation of lymphocyte mediated immunity,biological_process
59043,GO:0002708,"Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.",positive regulation of lymphocyte mediated immunity,biological_process
59044,GO:0002709,"Any process that modulates the frequency, rate, or extent of T cell mediated immunity.",regulation of T cell mediated immunity,biological_process
59045,GO:0002710,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.",negative regulation of T cell mediated immunity,biological_process
59046,GO:0002711,"Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.",positive regulation of T cell mediated immunity,biological_process
59047,GO:0002712,"Any process that modulates the frequency, rate, or extent of B cell mediated immunity.",regulation of B cell mediated immunity,biological_process
59048,GO:0002713,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.",negative regulation of B cell mediated immunity,biological_process
59049,GO:0002714,"Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.",positive regulation of B cell mediated immunity,biological_process
59050,GO:0002715,"Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.",regulation of natural killer cell mediated immunity,biological_process
59051,GO:0002716,"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.",negative regulation of natural killer cell mediated immunity,biological_process
59052,GO:0002717,"Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.",positive regulation of natural killer cell mediated immunity,biological_process
59053,GO:0002718,"Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.",regulation of cytokine production involved in immune response,biological_process
59054,GO:0002719,"Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.",negative regulation of cytokine production involved in immune response,biological_process
59055,GO:0002720,"Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.",positive regulation of cytokine production involved in immune response,biological_process
59056,GO:0002721,"Any process that modulates the frequency, rate, or extent of B cell cytokine production.",regulation of B cell cytokine production,biological_process
59057,GO:0002722,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.",negative regulation of B cell cytokine production,biological_process
59058,GO:0002723,"Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.",positive regulation of B cell cytokine production,biological_process
59059,GO:0002724,"Any process that modulates the frequency, rate, or extent of T cell cytokine production.",regulation of T cell cytokine production,biological_process
59060,GO:0002725,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.",negative regulation of T cell cytokine production,biological_process
59061,GO:0002726,"Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.",positive regulation of T cell cytokine production,biological_process
59062,GO:0002727,"Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.",regulation of natural killer cell cytokine production,biological_process
59063,GO:0002728,"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.",negative regulation of natural killer cell cytokine production,biological_process
59064,GO:0002729,"Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.",positive regulation of natural killer cell cytokine production,biological_process
59065,GO:0002730,"Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.",regulation of dendritic cell cytokine production,biological_process
59066,GO:0002731,"Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.",negative regulation of dendritic cell cytokine production,biological_process
59067,GO:0002732,"Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.",positive regulation of dendritic cell cytokine production,biological_process
59068,GO:0002733,"Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.",regulation of myeloid dendritic cell cytokine production,biological_process
59069,GO:0002734,"Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.",negative regulation of myeloid dendritic cell cytokine production,biological_process
59070,GO:0002735,"Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.",positive regulation of myeloid dendritic cell cytokine production,biological_process
59071,GO:0002736,"Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.",regulation of plasmacytoid dendritic cell cytokine production,biological_process
59072,GO:0002737,"Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.",negative regulation of plasmacytoid dendritic cell cytokine production,biological_process
59073,GO:0002738,"Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.",positive regulation of plasmacytoid dendritic cell cytokine production,biological_process
59074,GO:0002745,Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.,antigen processing and presentation initiated by receptor mediated uptake of antigen,biological_process
59075,GO:0002746,Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.,antigen processing and presentation following pinocytosis,biological_process
59076,GO:0002747,Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.,antigen processing and presentation following phagocytosis,biological_process
59077,GO:0002748,Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).,antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen,biological_process
59078,GO:0002750,Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.,antigen processing and presentation following macropinocytosis,biological_process
59079,GO:0002751,Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.,antigen processing and presentation following receptor mediated endocytosis,biological_process
59080,GO:0002752,"The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.",cell surface pattern recognition receptor signaling pathway,biological_process
59081,GO:0002753,"The series of molecular signals initiated by the binding of a ligand from another organism to a cytoplasmic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.",cytoplasmic pattern recognition receptor signaling pathway,biological_process
59082,GO:0002754,"The series of molecular signals initiated by the binding of a ligand to an intracellular vesicle pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.",endosomal pattern recognition receptor signaling pathway,biological_process
59083,GO:0002755,A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.,MyD88-dependent toll-like receptor signaling pathway,biological_process
59084,GO:0002756,A toll-like receptor signaling pathway not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate an immune response.,MyD88-independent toll-like receptor signaling pathway,biological_process
59085,GO:0002757,The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.,immune response-activating signaling pathway,biological_process
59086,GO:0002758,The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an innate immune response.,innate immune response-activating signaling pathway,biological_process
59087,GO:0002759,"Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.",regulation of antimicrobial humoral response,biological_process
59088,GO:0002760,"Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.",positive regulation of antimicrobial humoral response,biological_process
59089,GO:0002761,"Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.",regulation of myeloid leukocyte differentiation,biological_process
59090,GO:0002762,"Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.",negative regulation of myeloid leukocyte differentiation,biological_process
59091,GO:0002763,"Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.",positive regulation of myeloid leukocyte differentiation,biological_process
59092,GO:0002764,"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.",immune response-regulating signaling pathway,biological_process
59093,GO:0002765,"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.",immune response-inhibiting signal transduction,biological_process
59094,GO:0002766,"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.",innate immune response-inhibiting signal transduction,biological_process
59095,GO:0002767,The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of inhibiting an immune response.,immune response-inhibiting cell surface receptor signaling pathway,biological_process
59096,GO:0002768,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.",immune response-regulating cell surface receptor signaling pathway,biological_process
59097,GO:0002769,The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.,natural killer cell inhibitory signaling pathway,biological_process
59098,GO:0002770,The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.,T cell inhibitory signaling pathway,biological_process
59099,GO:0002771,The series of molecular signals initiated by an extracellular ligand binding to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.,inhibitory killer cell immunoglobulin-like receptor signaling pathway,biological_process
59100,GO:0002772,The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.,inhibitory C-type lectin receptor signaling pathway,biological_process
59101,GO:0002773,The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.,B cell inhibitory signaling pathway,biological_process
59102,GO:0002774,The series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.,Fc receptor mediated inhibitory signaling pathway,biological_process
59103,GO:0002775,"The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.",antimicrobial peptide production,biological_process
59104,GO:0002776,"The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.",antimicrobial peptide secretion,biological_process
59105,GO:0002777,"The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.",antimicrobial peptide biosynthetic process,biological_process
59106,GO:0002778,"The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.",antibacterial peptide production,biological_process
59107,GO:0002779,The regulated release of an antibacterial peptide from a cell or a tissue.,antibacterial peptide secretion,biological_process
59108,GO:0002780,The chemical reactions and pathways resulting in the formation of an antibacterial peptide.,antibacterial peptide biosynthetic process,biological_process
59109,GO:0002781,"The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.",antifungal peptide production,biological_process
59110,GO:0002782,The regulated release of an antifungal peptide from a cell or a tissue.,antifungal peptide secretion,biological_process
59111,GO:0002783,The chemical reactions and pathways resulting in the formation of an antifungal peptide.,antifungal peptide biosynthetic process,biological_process
59112,GO:0002784,"Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.",regulation of antimicrobial peptide production,biological_process
59113,GO:0002785,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.",negative regulation of antimicrobial peptide production,biological_process
59114,GO:0002786,"Any process that modulates the frequency, rate, or extent of antibacterial peptide production.",regulation of antibacterial peptide production,biological_process
59115,GO:0002787,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.",negative regulation of antibacterial peptide production,biological_process
59116,GO:0002788,"Any process that modulates the frequency, rate, or extent of antifungal peptide production.",regulation of antifungal peptide production,biological_process
59117,GO:0002789,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.",negative regulation of antifungal peptide production,biological_process
59118,GO:0002790,The controlled release of a peptide from a cell or a tissue.,peptide secretion,biological_process
59119,GO:0002791,"Any process that modulates the frequency, rate, or extent of peptide secretion.",regulation of peptide secretion,biological_process
59120,GO:0002792,"Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.",negative regulation of peptide secretion,biological_process
59121,GO:0002793,"Any process that activates or increases the frequency, rate, or extent of peptide secretion.",positive regulation of peptide secretion,biological_process
59122,GO:0002794,"Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.",regulation of antimicrobial peptide secretion,biological_process
59123,GO:0002795,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.",negative regulation of antimicrobial peptide secretion,biological_process
59124,GO:0002796,"Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.",positive regulation of antimicrobial peptide secretion,biological_process
59125,GO:0002797,"Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.",regulation of antibacterial peptide secretion,biological_process
59126,GO:0002798,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.",negative regulation of antibacterial peptide secretion,biological_process
59127,GO:0002799,"Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.",positive regulation of antibacterial peptide secretion,biological_process
59128,GO:0002800,"Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.",regulation of antifungal peptide secretion,biological_process
59129,GO:0002801,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.",negative regulation of antifungal peptide secretion,biological_process
59130,GO:0002802,"Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.",positive regulation of antifungal peptide secretion,biological_process
59131,GO:0002803,"Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.",positive regulation of antibacterial peptide production,biological_process
59132,GO:0002804,"Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.",positive regulation of antifungal peptide production,biological_process
59133,GO:0002805,"Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.",regulation of antimicrobial peptide biosynthetic process,biological_process
59134,GO:0002806,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.",negative regulation of antimicrobial peptide biosynthetic process,biological_process
59135,GO:0002807,"Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.",positive regulation of antimicrobial peptide biosynthetic process,biological_process
59136,GO:0002808,"Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.",regulation of antibacterial peptide biosynthetic process,biological_process
59137,GO:0002809,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.",negative regulation of antibacterial peptide biosynthetic process,biological_process
59138,GO:0002810,"Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.",regulation of antifungal peptide biosynthetic process,biological_process
59139,GO:0002811,"Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.",negative regulation of antifungal peptide biosynthetic process,biological_process
59140,GO:0002812,The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.,biosynthetic process of antibacterial peptides active against Gram-negative bacteria,biological_process
59141,GO:0002813,"Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.",regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria,biological_process
59142,GO:0002814,"Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.",negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria,biological_process
59143,GO:0002815,The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.,biosynthetic process of antibacterial peptides active against Gram-positive bacteria,biological_process
59144,GO:0002816,"Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.",regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria,biological_process
59145,GO:0002817,"Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.",negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria,biological_process
59146,GO:0002819,"Any process that modulates the frequency, rate, or extent of an adaptive immune response.",regulation of adaptive immune response,biological_process
59147,GO:0002820,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.",negative regulation of adaptive immune response,biological_process
59148,GO:0002821,"Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.",positive regulation of adaptive immune response,biological_process
59149,GO:0002822,"Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.",regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains,biological_process
59150,GO:0002823,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.",negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains,biological_process
59151,GO:0002824,"Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.",positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains,biological_process
59152,GO:0002825,"Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.",regulation of T-helper 1 type immune response,biological_process
59153,GO:0002826,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.",negative regulation of T-helper 1 type immune response,biological_process
59154,GO:0002827,"Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.",positive regulation of T-helper 1 type immune response,biological_process
59155,GO:0002828,"Any process that modulates the frequency, rate, or extent of a type 2 immune response.",regulation of type 2 immune response,biological_process
59156,GO:0002829,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.",negative regulation of type 2 immune response,biological_process
59157,GO:0002830,"Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.",positive regulation of type 2 immune response,biological_process
59158,GO:0002831,"Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.",regulation of response to biotic stimulus,biological_process
59159,GO:0002832,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.",negative regulation of response to biotic stimulus,biological_process
59160,GO:0002833,"Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.",positive regulation of response to biotic stimulus,biological_process
59161,GO:0002834,"Any process that modulates the frequency, rate, or extent of a response to tumor cell.",regulation of response to tumor cell,biological_process
59162,GO:0002835,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.",negative regulation of response to tumor cell,biological_process
59163,GO:0002836,"Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.",positive regulation of response to tumor cell,biological_process
59164,GO:0002837,"Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.",regulation of immune response to tumor cell,biological_process
59165,GO:0002838,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.",negative regulation of immune response to tumor cell,biological_process
59166,GO:0002839,"Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.",positive regulation of immune response to tumor cell,biological_process
59167,GO:0002840,"Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.",regulation of T cell mediated immune response to tumor cell,biological_process
59168,GO:0002841,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.",negative regulation of T cell mediated immune response to tumor cell,biological_process
59169,GO:0002842,"Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.",positive regulation of T cell mediated immune response to tumor cell,biological_process
59170,GO:0002843,"Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.",regulation of tolerance induction to tumor cell,biological_process
59171,GO:0002844,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.",negative regulation of tolerance induction to tumor cell,biological_process
59172,GO:0002845,"Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.",positive regulation of tolerance induction to tumor cell,biological_process
59173,GO:0002846,"Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.",regulation of T cell tolerance induction to tumor cell,biological_process
59174,GO:0002847,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.",negative regulation of T cell tolerance induction to tumor cell,biological_process
59175,GO:0002848,"Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.",positive regulation of T cell tolerance induction to tumor cell,biological_process
59176,GO:0002849,"Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.",regulation of peripheral T cell tolerance induction,biological_process
59177,GO:0002850,"Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.",negative regulation of peripheral T cell tolerance induction,biological_process
59178,GO:0002851,"Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.",positive regulation of peripheral T cell tolerance induction,biological_process
59179,GO:0002852,"Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.",regulation of T cell mediated cytotoxicity directed against tumor cell target,biological_process
59180,GO:0002853,"Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.",negative regulation of T cell mediated cytotoxicity directed against tumor cell target,biological_process
59181,GO:0002854,"Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.",positive regulation of T cell mediated cytotoxicity directed against tumor cell target,biological_process
59182,GO:0002855,"Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.",regulation of natural killer cell mediated immune response to tumor cell,biological_process
59183,GO:0002856,"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.",negative regulation of natural killer cell mediated immune response to tumor cell,biological_process
59184,GO:0002857,"Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.",positive regulation of natural killer cell mediated immune response to tumor cell,biological_process
59185,GO:0002858,"Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.",regulation of natural killer cell mediated cytotoxicity directed against tumor cell target,biological_process
59186,GO:0002859,"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.",negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target,biological_process
59187,GO:0002860,"Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.",positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target,biological_process
59188,GO:0002861,"Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.",regulation of inflammatory response to antigenic stimulus,biological_process
59189,GO:0002862,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.",negative regulation of inflammatory response to antigenic stimulus,biological_process
59190,GO:0002863,"Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.",positive regulation of inflammatory response to antigenic stimulus,biological_process
59191,GO:0002864,"Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.",regulation of acute inflammatory response to antigenic stimulus,biological_process
59192,GO:0002865,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.",negative regulation of acute inflammatory response to antigenic stimulus,biological_process
59193,GO:0002866,"Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.",positive regulation of acute inflammatory response to antigenic stimulus,biological_process
59194,GO:0002867,"Any process that modulates the frequency, rate, or extent of B cell deletion.",regulation of B cell deletion,biological_process
59195,GO:0002868,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.",negative regulation of B cell deletion,biological_process
59196,GO:0002869,"Any process that activates or increases the frequency, rate, or extent of B cell deletion.",positive regulation of B cell deletion,biological_process
59197,GO:0002870,"Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.",T cell anergy,biological_process
59198,GO:0002871,"Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.",regulation of natural killer cell tolerance induction,biological_process
59199,GO:0002872,"Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.",negative regulation of natural killer cell tolerance induction,biological_process
59200,GO:0002873,"Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.",positive regulation of natural killer cell tolerance induction,biological_process
59201,GO:0002874,"Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.",regulation of chronic inflammatory response to antigenic stimulus,biological_process
59202,GO:0002875,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.",negative regulation of chronic inflammatory response to antigenic stimulus,biological_process
59203,GO:0002876,"Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.",positive regulation of chronic inflammatory response to antigenic stimulus,biological_process
59204,GO:0002877,"Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.",regulation of acute inflammatory response to non-antigenic stimulus,biological_process
59205,GO:0002878,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.",negative regulation of acute inflammatory response to non-antigenic stimulus,biological_process
59206,GO:0002879,"Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.",positive regulation of acute inflammatory response to non-antigenic stimulus,biological_process
59207,GO:0002880,"Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.",regulation of chronic inflammatory response to non-antigenic stimulus,biological_process
59208,GO:0002881,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.",negative regulation of chronic inflammatory response to non-antigenic stimulus,biological_process
59209,GO:0002882,"Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.",positive regulation of chronic inflammatory response to non-antigenic stimulus,biological_process
59210,GO:0002883,"Any process that modulates the frequency, rate, or extent of hypersensitivity.",regulation of hypersensitivity,biological_process
59211,GO:0002884,"Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.",negative regulation of hypersensitivity,biological_process
59212,GO:0002885,"Any process that activates or increases the frequency, rate, or extent of hypersensitivity.",positive regulation of hypersensitivity,biological_process
59213,GO:0002886,"Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.",regulation of myeloid leukocyte mediated immunity,biological_process
59214,GO:0002887,"Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.",negative regulation of myeloid leukocyte mediated immunity,biological_process
59215,GO:0002888,"Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.",positive regulation of myeloid leukocyte mediated immunity,biological_process
59216,GO:0002889,"Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.",regulation of immunoglobulin mediated immune response,biological_process
59217,GO:0002890,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.",negative regulation of immunoglobulin mediated immune response,biological_process
59218,GO:0002891,"Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.",positive regulation of immunoglobulin mediated immune response,biological_process
59219,GO:0002892,"Any process that modulates the frequency, rate, or extent of type II hypersensitivity.",regulation of type II hypersensitivity,biological_process
59220,GO:0002893,"Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.",negative regulation of type II hypersensitivity,biological_process
59221,GO:0002894,"Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.",positive regulation of type II hypersensitivity,biological_process
59222,GO:0002895,"Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.",regulation of central B cell tolerance induction,biological_process
59223,GO:0002896,"Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.",negative regulation of central B cell tolerance induction,biological_process
59224,GO:0002897,"Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.",positive regulation of central B cell tolerance induction,biological_process
59225,GO:0002898,"Any process that modulates the frequency, rate, or extent of central B cell deletion.",regulation of central B cell deletion,biological_process
59226,GO:0002899,"Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.",negative regulation of central B cell deletion,biological_process
59227,GO:0002900,"Any process that activates or increases the frequency, rate, or extent of central B cell deletion.",positive regulation of central B cell deletion,biological_process
59228,GO:0002901,"Any apoptotic process in a B cell that is mature, having left the bone marrow.",mature B cell apoptotic process,biological_process
59229,GO:0002902,"Any process that modulates the frequency, rate, or extent of B cell apoptotic process.",regulation of B cell apoptotic process,biological_process
59230,GO:0002903,"Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.",negative regulation of B cell apoptotic process,biological_process
59231,GO:0002904,"Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.",positive regulation of B cell apoptotic process,biological_process
59232,GO:0002905,"Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.",regulation of mature B cell apoptotic process,biological_process
59233,GO:0002906,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.",negative regulation of mature B cell apoptotic process,biological_process
59234,GO:0002907,"Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.",positive regulation of mature B cell apoptotic process,biological_process
59235,GO:0002908,"Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.",regulation of peripheral B cell deletion,biological_process
59236,GO:0002909,"Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.",negative regulation of peripheral B cell deletion,biological_process
59237,GO:0002910,"Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.",positive regulation of peripheral B cell deletion,biological_process
59238,GO:0002911,"Any process that modulates the frequency, rate, or extent of lymphocyte anergy.",regulation of lymphocyte anergy,biological_process
59239,GO:0002912,"Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.",negative regulation of lymphocyte anergy,biological_process
59240,GO:0002913,"Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.",positive regulation of lymphocyte anergy,biological_process
59241,GO:0002914,"Any process that modulates the frequency, rate, or extent of central B cell anergy.",regulation of central B cell anergy,biological_process
59242,GO:0002915,"Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.",negative regulation of central B cell anergy,biological_process
59243,GO:0002916,"Any process that activates or increases the frequency, rate, or extent of central B cell anergy.",positive regulation of central B cell anergy,biological_process
59244,GO:0002917,"Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.",regulation of peripheral B cell anergy,biological_process
59245,GO:0002918,"Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.",negative regulation of peripheral B cell anergy,biological_process
59246,GO:0002919,"Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.",positive regulation of peripheral B cell anergy,biological_process
59247,GO:0002920,"Any process that modulates the frequency, rate, or extent of a humoral immune response.",regulation of humoral immune response,biological_process
59248,GO:0002921,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.",negative regulation of humoral immune response,biological_process
59249,GO:0002922,"Any process that activates or increases the frequency, rate, or extent of a humoral immune response.",positive regulation of humoral immune response,biological_process
59250,GO:0002923,"Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.",regulation of humoral immune response mediated by circulating immunoglobulin,biological_process
59251,GO:0002924,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.",negative regulation of humoral immune response mediated by circulating immunoglobulin,biological_process
59252,GO:0002925,"Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.",positive regulation of humoral immune response mediated by circulating immunoglobulin,biological_process
59253,GO:0002926,The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.,tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation,biological_process
59254,GO:0002927,"The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.",archaeosine-tRNA biosynthetic process,biological_process
59255,GO:0002929,A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.,MECO complex,cellular_component
59256,GO:0002930,"The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.",trabecular meshwork development,biological_process
59257,GO:0002931,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.",response to ischemia,biological_process
59258,GO:0002932,"The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.",tendon sheath development,biological_process
59259,GO:0002933,The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.,lipid hydroxylation,biological_process
59260,GO:0002934,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.",desmosome organization,biological_process
59261,GO:0002935,Catalysis of the reaction: adenosine37 in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine37 in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.,tRNA (adenine(37)-C2)-methyltransferase activity,molecular_function
59262,GO:0002936,The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.,bradykinin biosynthetic process,biological_process
59263,GO:0002937,"The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.",tRNA 4-thiouridine biosynthesis,biological_process
59264,GO:0002938,The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.,tRNA guanine ribose methylation,biological_process
59265,GO:0002939,The process whereby a guanine in tRNA is methylated at position N1 of the guanine.,tRNA N1-guanine methylation,biological_process
59266,GO:0002940,The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.,tRNA N2-guanine methylation,biological_process
59267,GO:0002941,"The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.",synoviocyte proliferation,biological_process
59268,GO:0002942,The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.,"tRNA m2,2-guanine biosynthesis",biological_process
59269,GO:0002943,The process whereby a uridine in a transfer RNA is converted to dihydrouridine.,tRNA dihydrouridine synthesis,biological_process
59270,GO:0002944,A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin K-CDK12 complex,cellular_component
59271,GO:0002945,A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin K-CDK13 complex,cellular_component
59272,GO:0002946,The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.,tRNA C5-cytosine methylation,biological_process
59273,GO:0002947,A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.,tumor necrosis factor receptor superfamily complex,cellular_component
59274,GO:0002948,Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.,archaeosine synthase activity,molecular_function
59275,GO:0002949,"The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).",tRNA threonylcarbamoyladenosine modification,biological_process
59276,GO:0002950,Catalysis of the reaction: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H+.,ceramide phosphoethanolamine synthase activity,molecular_function
59277,GO:0002951,Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate.,leukotriene-C(4) hydrolase activity,molecular_function
59278,GO:0002952,"Catalysis of the reaction: (2S)-2-hydroxy-3,4-dioxopentyl phosphate = 3-hydroxy-2,4-dioxopentyl phosphate.","(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity",molecular_function
59279,GO:0002953,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate.,5'-deoxynucleotidase activity,molecular_function
59280,GO:0003002,The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.,regionalization,biological_process
59281,GO:0003006,"A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.",developmental process involved in reproduction,biological_process
59282,GO:0003007,"The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.",heart morphogenesis,biological_process
59283,GO:0003008,A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.,system process,biological_process
59284,GO:0003009,"A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.",skeletal muscle contraction,biological_process
59285,GO:0003010,"A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under co...",voluntary skeletal muscle contraction,biological_process
59286,GO:0003011,"A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.",involuntary skeletal muscle contraction,biological_process
59287,GO:0003012,An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.,muscle system process,biological_process
59288,GO:0003013,An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.,circulatory system process,biological_process
59289,GO:0003014,"An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Dr...",renal system process,biological_process
59290,GO:0003015,"A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.",heart process,biological_process
59291,GO:0003016,A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.,respiratory system process,biological_process
59292,GO:0003017,The flow of lymph through the body of an animal.,lymph circulation,biological_process
59293,GO:0003018,A circulatory process that occurs at the level of the vasculature.,vascular process in circulatory system,biological_process
59294,GO:0003019,The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.,central nervous system control of baroreceptor feedback,biological_process
59295,GO:0003020,The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.,detection of reduced oxygen by chemoreceptor signaling,biological_process
59296,GO:0003021,The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.,detection of increased carbon dioxide by chemoreceptor signaling,biological_process
59297,GO:0003022,The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.,detection of pH by chemoreceptor signaling,biological_process
59298,GO:0003023,The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.,baroreceptor detection of increased arterial stretch,biological_process
59299,GO:0003024,The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.,baroreceptor detection of decreased arterial stretch,biological_process
59300,GO:0003025,The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.,regulation of systemic arterial blood pressure by baroreceptor feedback,biological_process
59301,GO:0003026,The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.,regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback,biological_process
59302,GO:0003027,"The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.",regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling,biological_process
59303,GO:0003028,"The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.",regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling,biological_process
59304,GO:0003029,The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.,detection of hypoxic conditions in blood by carotid body chemoreceptor signaling,biological_process
59305,GO:0003030,The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.,detection of hydrogen ion,biological_process
59306,GO:0003031,The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.,detection of carbon dioxide,biological_process
59307,GO:0003032,The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.,detection of oxygen,biological_process
59308,GO:0003033,The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.,detection of hypoxic conditions in blood by aortic body chemoreceptor signaling,biological_process
59309,GO:0003034,The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.,detection of increased carbon dioxide by aortic body chemoreceptor signaling,biological_process
59310,GO:0003035,The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.,detection of increased carbon dioxide by carotid body chemoreceptor signaling,biological_process
59311,GO:0003036,The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.,detection of pH by aortic body chemoreceptor signaling,biological_process
59312,GO:0003037,The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.,detection of pH by carotid body chemoreceptor signaling,biological_process
59313,GO:0003038,The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.,detection of reduced oxygen by aortic body chemoreceptor signaling,biological_process
59314,GO:0003039,The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.,detection of reduced oxygen by carotid body chemoreceptor signaling,biological_process
59315,GO:0003040,"The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.",excitation of vasomotor center by aortic body chemoreceptor signaling,biological_process
59316,GO:0003041,"The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.",excitation of vasomotor center by carotid body chemoreceptor signaling,biological_process
59317,GO:0003044,"The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.",regulation of systemic arterial blood pressure mediated by a chemical signal,biological_process
59318,GO:0003045,The regulation of blood pressure mediated by detection of forces within the circulatory system.,regulation of systemic arterial blood pressure by physical factors,biological_process
59319,GO:0003046,"The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.",regulation of systemic arterial blood pressure by stress relaxation,biological_process
59320,GO:0003047,The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.,regulation of systemic arterial blood pressure by epinephrine,biological_process
59321,GO:0003048,The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.,regulation of systemic arterial blood pressure by norepinephrine,biological_process
59322,GO:0003049,The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.,regulation of systemic arterial blood pressure by capillary fluid shift,biological_process
59323,GO:0003050,The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.,regulation of systemic arterial blood pressure by atrial natriuretic peptide,biological_process
59324,GO:0003051,The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.,angiotensin-mediated drinking behavior,biological_process
59325,GO:0003052,Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.,circadian regulation of systemic arterial blood pressure,biological_process
59326,GO:0003053,Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.,circadian regulation of heart rate,biological_process
59327,GO:0003054,The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.,circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus,biological_process
59328,GO:0003055,The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.,circadian regulation of heart rate by the suprachiasmatic nucleus,biological_process
59329,GO:0003056,"Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.",regulation of vascular associated smooth muscle contraction,biological_process
59330,GO:0003057,"The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.",regulation of the force of heart contraction by chemical signal,biological_process
59331,GO:0003058,"The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.",hormonal regulation of the force of heart contraction,biological_process
59332,GO:0003059,The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.,positive regulation of the force of heart contraction by epinephrine,biological_process
59333,GO:0003060,The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.,negative regulation of the force of heart contraction by acetylcholine,biological_process
59334,GO:0003061,The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.,positive regulation of the force of heart contraction by norepinephrine,biological_process
59335,GO:0003062,"The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.",regulation of heart rate by chemical signal,biological_process
59336,GO:0003063,The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.,negative regulation of heart rate by acetylcholine,biological_process
59337,GO:0003064,"The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.",regulation of heart rate by hormone,biological_process
59338,GO:0003065,The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.,positive regulation of heart rate by epinephrine,biological_process
59339,GO:0003066,The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.,positive regulation of heart rate by norepinephrine,biological_process
59340,GO:0003067,"The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.",circadian regulation of systemic arterial blood pressure by hormone,biological_process
59341,GO:0003068,The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.,regulation of systemic arterial blood pressure by acetylcholine,biological_process
59342,GO:0003069,"The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.",acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure,biological_process
59343,GO:0003070,The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.,regulation of systemic arterial blood pressure by neurotransmitter,biological_process
59344,GO:0003071,Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.,renal system process involved in regulation of systemic arterial blood pressure,biological_process
59345,GO:0003073,The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.,regulation of systemic arterial blood pressure,biological_process
59346,GO:0003081,The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.,regulation of systemic arterial blood pressure by renin-angiotensin,biological_process
59347,GO:0003083,The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.,negative regulation of renal output by angiotensin,biological_process
59348,GO:0003084,The process that increases the force with which blood travels through the systemic arterial circulatory system.,positive regulation of systemic arterial blood pressure,biological_process
59349,GO:0003085,The process that reduces the force with which blood travels through the systemic arterial circulatory system.,negative regulation of systemic arterial blood pressure,biological_process
59350,GO:0003086,The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.,regulation of systemic arterial blood pressure by local renal renin-angiotensin,biological_process
59351,GO:0003087,The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.,positive regulation of the force of heart contraction by neuronal epinephrine,biological_process
59352,GO:0003088,The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.,positive regulation of the force of heart contraction by circulating epinephrine,biological_process
59353,GO:0003089,Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.,positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine,biological_process
59354,GO:0003090,Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.,positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine,biological_process
59355,GO:0003091,Renal process involved in the maintenance of an internal steady state of water in the body.,renal water homeostasis,biological_process
59356,GO:0003092,The process in which renal water excretion is decreased.,renal water retention,biological_process
59357,GO:0003093,"Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.",regulation of glomerular filtration,biological_process
59358,GO:0003094,"The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.",glomerular filtration,biological_process
59359,GO:0003095,The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).,pressure natriuresis,biological_process
59360,GO:0003096,The directed movement of sodium ions (Na+) by the renal system.,renal sodium ion transport,biological_process
59361,GO:0003097,The directed movement of water (H2O) by the renal system.,renal water transport,biological_process
59362,GO:0003099,"Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.",positive regulation of the force of heart contraction by chemical signal,biological_process
59363,GO:0003100,"The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.",regulation of systemic arterial blood pressure by endothelin,biological_process
59364,GO:0003101,The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.,regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine,biological_process
59365,GO:0003104,"Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.",positive regulation of glomerular filtration,biological_process
59366,GO:0003105,"Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.",negative regulation of glomerular filtration,biological_process
59367,GO:0003106,The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.,negative regulation of glomerular filtration by angiotensin,biological_process
59368,GO:0003108,"Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.",negative regulation of the force of heart contraction by chemical signal,biological_process
59369,GO:0003109,The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.,positive regulation of the force of heart contraction by circulating norepinephrine,biological_process
59370,GO:0003110,The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.,positive regulation of the force of heart contraction by neuronal norepinephrine,biological_process
59371,GO:0003111,The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.,positive regulation of heart rate by circulating epinephrine,biological_process
59372,GO:0003112,The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction.,positive regulation of heart rate by neuronal epinephrine,biological_process
59373,GO:0003113,The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.,positive regulation of heart rate by neuronal norepinephrine,biological_process
59374,GO:0003114,The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.,positive regulation of heart rate by circulating norepinephrine,biological_process
59375,GO:0003115,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.",regulation of vasoconstriction by epinephrine,biological_process
59376,GO:0003116,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.",regulation of vasoconstriction by norepinephrine,biological_process
59377,GO:0003117,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.",regulation of vasoconstriction by circulating norepinephrine,biological_process
59378,GO:0003118,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings.",regulation of vasoconstriction by neuronal norepinephrine,biological_process
59379,GO:0003119,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.",regulation of vasoconstriction by neuronal epinephrine,biological_process
59380,GO:0003120,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.",regulation of vasoconstriction by circulating epinephrine,biological_process
59381,GO:0003121,A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.,epinephrine-mediated vasodilation,biological_process
59382,GO:0003122,A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings.,norepinephrine-mediated vasodilation,biological_process
59383,GO:0003127,The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.,detection of nodal flow,biological_process
59384,GO:0003128,The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.,heart field specification,biological_process
59385,GO:0003129,The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.,heart induction,biological_process
59386,GO:0003131,Any process that mediates the transfer of information from mesodermal cells to endodermal cells.,mesodermal-endodermal cell signaling,biological_process
59387,GO:0003133,Any process that mediates the transfer of information from endodermal cells to mesodermal cells.,endodermal-mesodermal cell signaling,biological_process
59388,GO:0003138,The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.,primary heart field specification,biological_process
59389,GO:0003139,"The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).",secondary heart field specification,biological_process
59390,GO:0003140,The establishment of the lateral mesoderm with respect to the left and right halves.,determination of left/right asymmetry in lateral mesoderm,biological_process
59391,GO:0003142,The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.,cardiogenic plate morphogenesis,biological_process
59392,GO:0003143,The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.,embryonic heart tube morphogenesis,biological_process
59393,GO:0003144,The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.,embryonic heart tube formation,biological_process
59394,GO:0003145,The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.,embryonic heart tube formation via epithelial folding,biological_process
59395,GO:0003146,The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.,heart jogging,biological_process
59396,GO:0003147,The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.,neural crest cell migration involved in heart formation,biological_process
59397,GO:0003148,The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.,outflow tract septum morphogenesis,biological_process
59398,GO:0003149,The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.,membranous septum morphogenesis,biological_process
59399,GO:0003150,The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.,muscular septum morphogenesis,biological_process
59400,GO:0003151,The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.,outflow tract morphogenesis,biological_process
59401,GO:0003153,Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.,closure of embryonic heart tube,biological_process
59402,GO:0003156,"Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.",regulation of animal organ formation,biological_process
59403,GO:0003157,"The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.",endocardium development,biological_process
59404,GO:0003158,"The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.",endothelium development,biological_process
59405,GO:0003159,"The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.",morphogenesis of an endothelium,biological_process
59406,GO:0003160,"The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.",endocardium morphogenesis,biological_process
59407,GO:0003161,"The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.",cardiac conduction system development,biological_process
59408,GO:0003162,"The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.",atrioventricular node development,biological_process
59409,GO:0003163,"The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.",sinoatrial node development,biological_process
59410,GO:0003164,"The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.",His-Purkinje system development,biological_process
59411,GO:0003165,"The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.",Purkinje myocyte development,biological_process
59412,GO:0003166,"The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.",bundle of His development,biological_process
59413,GO:0003167,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.,atrioventricular bundle cell differentiation,biological_process
59414,GO:0003168,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.,Purkinje myocyte differentiation,biological_process
59415,GO:0003169,The process in which the anatomical structures of veins of the heart are generated and organized.,coronary vein morphogenesis,biological_process
59416,GO:0003170,"The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.",heart valve development,biological_process
59417,GO:0003171,"The progression of the atrioventricular valve over time, from its formation to the mature structure.",atrioventricular valve development,biological_process
59418,GO:0003172,"The progression of the sinoatrial valve over time, from its formation to the mature structure.",sinoatrial valve development,biological_process
59419,GO:0003173,"The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.",ventriculo bulbo valve development,biological_process
59420,GO:0003174,"The progression of the mitral valve over time, from its formation to the mature structure.",mitral valve development,biological_process
59421,GO:0003175,"The progression of the tricuspid valve over time, from its formation to the mature structure.",tricuspid valve development,biological_process
59422,GO:0003176,"The progression of the aortic valve over time, from its formation to the mature structure.",aortic valve development,biological_process
59423,GO:0003177,"The progression of the pulmonary valve over time, from its formation to the mature structure.",pulmonary valve development,biological_process
59424,GO:0003178,"The progression of the valve of the coronary sinus over time, from its formation to the mature structure.",coronary sinus valve development,biological_process
59425,GO:0003179,The process in which the structure of a heart valve is generated and organized.,heart valve morphogenesis,biological_process
59426,GO:0003180,The process in which the structure of the aortic valve is generated and organized.,aortic valve morphogenesis,biological_process
59427,GO:0003181,The process in which the structure of the atrioventricular valve is generated and organized.,atrioventricular valve morphogenesis,biological_process
59428,GO:0003182,The process in which the structure of the coronary sinus valve is generated and organized.,coronary sinus valve morphogenesis,biological_process
59429,GO:0003183,The process in which the structure of the mitral valve is generated and organized.,mitral valve morphogenesis,biological_process
59430,GO:0003184,The process in which the structure of the pulmonary valve is generated and organized.,pulmonary valve morphogenesis,biological_process
59431,GO:0003185,The process in which the structure of the sinoatrial valve is generated and organized.,sinoatrial valve morphogenesis,biological_process
59432,GO:0003186,The process in which the structure of the tricuspid valve is generated and organized.,tricuspid valve morphogenesis,biological_process
59433,GO:0003187,The process in which the structure of the ventriculo bulbo valve is generated and organized.,ventriculo bulbo valve morphogenesis,biological_process
59434,GO:0003188,The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,heart valve formation,biological_process
59435,GO:0003189,The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,aortic valve formation,biological_process
59436,GO:0003190,The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,atrioventricular valve formation,biological_process
59437,GO:0003191,The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,coronary sinus valve formation,biological_process
59438,GO:0003192,The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,mitral valve formation,biological_process
59439,GO:0003193,The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,pulmonary valve formation,biological_process
59440,GO:0003194,The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,sinoatrial valve formation,biological_process
59441,GO:0003195,The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,tricuspid valve formation,biological_process
59442,GO:0003196,The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.,ventriculo bulbo valve formation,biological_process
59443,GO:0003197,"The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.",endocardial cushion development,biological_process
59444,GO:0003198,"A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.",epithelial to mesenchymal transition involved in endocardial cushion formation,biological_process
59445,GO:0003199,"A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.",endocardial cushion to mesenchymal transition involved in heart valve formation,biological_process
59446,GO:0003201,"A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature.",epithelial to mesenchymal transition involved in coronary vasculature morphogenesis,biological_process
59447,GO:0003203,The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.,endocardial cushion morphogenesis,biological_process
59448,GO:0003204,"The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.",cardiac skeleton development,biological_process
59449,GO:0003205,"The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.",cardiac chamber development,biological_process
59450,GO:0003206,The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.,cardiac chamber morphogenesis,biological_process
59451,GO:0003207,The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.,cardiac chamber formation,biological_process
59452,GO:0003208,The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.,cardiac ventricle morphogenesis,biological_process
59453,GO:0003209,The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.,cardiac atrium morphogenesis,biological_process
59454,GO:0003210,The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.,cardiac atrium formation,biological_process
59455,GO:0003211,The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.,cardiac ventricle formation,biological_process
59456,GO:0003212,The process in which the left cardiac atrium is generated and organized.,cardiac left atrium morphogenesis,biological_process
59457,GO:0003213,The process in which the right cardiac atrium is generated and organized.,cardiac right atrium morphogenesis,biological_process
59458,GO:0003214,The process in which the left cardiac ventricle is generated and organized.,cardiac left ventricle morphogenesis,biological_process
59459,GO:0003215,The process in which the right cardiac ventricle is generated and organized.,cardiac right ventricle morphogenesis,biological_process
59460,GO:0003216,The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.,cardiac left atrium formation,biological_process
59461,GO:0003217,The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.,cardiac right atrium formation,biological_process
59462,GO:0003218,The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.,cardiac left ventricle formation,biological_process
59463,GO:0003219,The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.,cardiac right ventricle formation,biological_process
59464,GO:0003220,The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.,left ventricular cardiac muscle tissue morphogenesis,biological_process
59465,GO:0003221,The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.,right ventricular cardiac muscle tissue morphogenesis,biological_process
59466,GO:0003222,The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.,ventricular trabecula myocardium morphogenesis,biological_process
59467,GO:0003223,The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.,ventricular compact myocardium morphogenesis,biological_process
59468,GO:0003224,The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.,left ventricular compact myocardium morphogenesis,biological_process
59469,GO:0003225,The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.,left ventricular trabecular myocardium morphogenesis,biological_process
59470,GO:0003226,The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.,right ventricular compact myocardium morphogenesis,biological_process
59471,GO:0003227,The process in which the anatomical structures of the right ventricular myocardium are generated and organized.,right ventricular trabecular myocardium morphogenesis,biological_process
59472,GO:0003228,"The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.",atrial cardiac muscle tissue development,biological_process
59473,GO:0003229,"The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.",ventricular cardiac muscle tissue development,biological_process
59474,GO:0003230,"The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.",cardiac atrium development,biological_process
59475,GO:0003231,"The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.",cardiac ventricle development,biological_process
59476,GO:0003232,"The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.",bulbus arteriosus development,biological_process
59477,GO:0003233,The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.,bulbus arteriosus morphogenesis,biological_process
59478,GO:0003234,The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.,bulbus arteriosus formation,biological_process
59479,GO:0003235,"The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.",sinus venosus development,biological_process
59480,GO:0003236,The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.,sinus venosus morphogenesis,biological_process
59481,GO:0003237,The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.,sinus venosus formation,biological_process
59482,GO:0003238,"The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.",conus arteriosus development,biological_process
59483,GO:0003239,The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.,conus arteriosus morphogenesis,biological_process
59484,GO:0003240,The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.,conus arteriosus formation,biological_process
59485,GO:0003241,Developmental growth that contributes to the shaping of the heart.,growth involved in heart morphogenesis,biological_process
59486,GO:0003242,"The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.",cardiac chamber ballooning,biological_process
59487,GO:0003243,The morphogenetic growth in which the left ventricle grows expanding its external boundary.,circumferential growth involved in left ventricle morphogenesis,biological_process
59488,GO:0003245,The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.,cardiac muscle tissue growth involved in heart morphogenesis,biological_process
59489,GO:0003247,The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart.,post-embryonic cardiac muscle cell growth involved in heart morphogenesis,biological_process
59490,GO:0003248,The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.,heart capillary growth,biological_process
59491,GO:0003253,The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.,cardiac neural crest cell migration involved in outflow tract morphogenesis,biological_process
59492,GO:0003254,"Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.",regulation of membrane depolarization,biological_process
59493,GO:0003255,"The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate.",endocardial precursor cell differentiation,biological_process
59494,GO:0003259,"The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast anterior-lateral migration,biological_process
59495,GO:0003260,"The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast migration,biological_process
59496,GO:0003261,"The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart.",cardiac muscle progenitor cell migration to the midline involved in heart field formation,biological_process
59497,GO:0003262,"The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.",endocardial progenitor cell migration to the midline involved in heart field formation,biological_process
59498,GO:0003263,"The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast proliferation,biological_process
59499,GO:0003264,"Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",regulation of cardioblast proliferation,biological_process
59500,GO:0003265,"Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.",regulation of primary heart field cardioblast proliferation,biological_process
59501,GO:0003266,"Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).",regulation of secondary heart field cardioblast proliferation,biological_process
59502,GO:0003270,"The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation,biological_process
59503,GO:0003271,"The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation,biological_process
59504,GO:0003272,The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.,endocardial cushion formation,biological_process
59505,GO:0003273,The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.,cell migration involved in endocardial cushion formation,biological_process
59506,GO:0003274,The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.,endocardial cushion fusion,biological_process
59507,GO:0003275,Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.,apoptotic process involved in outflow tract morphogenesis,biological_process
59508,GO:0003277,Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.,apoptotic process involved in endocardial cushion morphogenesis,biological_process
59509,GO:0003278,Any apoptotic process that contributes to the shaping of the heart.,apoptotic process involved in heart morphogenesis,biological_process
59510,GO:0003279,"The progression of a cardiac septum over time, from its initial formation to the mature structure.",cardiac septum development,biological_process
59511,GO:0003281,The progression of the ventricular septum over time from its formation to the mature structure.,ventricular septum development,biological_process
59512,GO:0003282,"The progression of the ventricular septum intermedium over time, from its formation to the mature structure.",ventricular septum intermedium development,biological_process
59513,GO:0003283,"The progression of the atrial septum over time, from its initial formation to the mature structure.",atrial septum development,biological_process
59514,GO:0003284,"The progression of the septum primum over time, from its formation to the mature structure.",septum primum development,biological_process
59515,GO:0003285,"The progression of the septum secundum over time, from its initial formation to the mature structure.",septum secundum development,biological_process
59516,GO:0003286,"The progression of the atrial septum intermedium over time, from its formation to the mature structure.",atrial septum intermedium development,biological_process
59517,GO:0003288,The developmental process in which a ventricular septum intermedium is generated and organized.,ventricular septum intermedium morphogenesis,biological_process
59518,GO:0003289,The process in which anatomical structure of an atrial septum primum is generated and organized.,atrial septum primum morphogenesis,biological_process
59519,GO:0003290,The process in which anatomical structure of an atrial septum secundum is generated and organized.,atrial septum secundum morphogenesis,biological_process
59520,GO:0003291,The process in which anatomical structure of an atrial septum intermedium is generated and organized.,atrial septum intermedium morphogenesis,biological_process
59521,GO:0003292,The process in which an endocardial cushion cell becomes a cell of a cardiac septum.,cardiac septum cell differentiation,biological_process
59522,GO:0003293,The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.,heart valve cell differentiation,biological_process
59523,GO:0003294,The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.,atrial ventricular junction remodeling,biological_process
59524,GO:0003297,"The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart.",heart wedging,biological_process
59525,GO:0003298,The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.,physiological muscle hypertrophy,biological_process
59526,GO:0003299,The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.,muscle hypertrophy in response to stress,biological_process
59527,GO:0003300,The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.,cardiac muscle hypertrophy,biological_process
59528,GO:0003301,The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.,physiological cardiac muscle hypertrophy,biological_process
59529,GO:0003305,The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.,cell migration involved in heart jogging,biological_process
59530,GO:0003306,"The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.",Wnt signaling pathway involved in heart development,biological_process
59531,GO:0003308,"Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.",negative regulation of Wnt signaling pathway involved in heart development,biological_process
59532,GO:0003309,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.,type B pancreatic cell differentiation,biological_process
59533,GO:0003310,The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.,pancreatic A cell differentiation,biological_process
59534,GO:0003311,The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.,pancreatic D cell differentiation,biological_process
59535,GO:0003312,The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.,pancreatic PP cell differentiation,biological_process
59536,GO:0003313,"The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.",heart rudiment development,biological_process
59537,GO:0003314,The process in which the anatomical structures of the heart rudiment are generated and organized.,heart rudiment morphogenesis,biological_process
59538,GO:0003315,The developmental process pertaining to the initial formation of the heart rudiment.,heart rudiment formation,biological_process
59539,GO:0003316,The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment.,establishment of myocardial progenitor cell apical/basal polarity,biological_process
59540,GO:0003317,The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment.,cardioblast cell midline fusion,biological_process
59541,GO:0003318,The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.,cell migration to the midline involved in heart development,biological_process
59542,GO:0003319,The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.,cardioblast migration to the midline involved in heart rudiment formation,biological_process
59543,GO:0003320,The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube.,heart rudiment involution,biological_process
59544,GO:0003321,Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.,positive regulation of blood pressure by epinephrine-norepinephrine,biological_process
59545,GO:0003322,"The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.",pancreatic A cell development,biological_process
59546,GO:0003323,"The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.",type B pancreatic cell development,biological_process
59547,GO:0003324,"The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.",pancreatic D cell development,biological_process
59548,GO:0003325,"The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.",pancreatic PP cell development,biological_process
59549,GO:0003326,The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.,pancreatic A cell fate commitment,biological_process
59550,GO:0003327,The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.,type B pancreatic cell fate commitment,biological_process
59551,GO:0003328,The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin.,pancreatic D cell fate commitment,biological_process
59552,GO:0003329,The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.,pancreatic PP cell fate commitment,biological_process
59553,GO:0003330,"Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.",regulation of extracellular matrix constituent secretion,biological_process
59554,GO:0003331,"Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.",positive regulation of extracellular matrix constituent secretion,biological_process
59555,GO:0003332,"Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.",negative regulation of extracellular matrix constituent secretion,biological_process
59556,GO:0003333,The process in which an amino acid is transported across a membrane.,amino acid transmembrane transport,biological_process
59557,GO:0003334,"The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.",keratinocyte development,biological_process
59558,GO:0003335,"The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.",corneocyte development,biological_process
59559,GO:0003336,The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.,corneocyte desquamation,biological_process
59560,GO:0003337,"A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.",mesenchymal to epithelial transition involved in metanephros morphogenesis,biological_process
59561,GO:0003338,The process in which the anatomical structures of the metanephros are generated and organized.,metanephros morphogenesis,biological_process
59562,GO:0003339,"Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.",regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis,biological_process
59563,GO:0003340,"Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.",negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis,biological_process
59564,GO:0003341,"The directed, self-propelled movement of a cilium.",cilium movement,biological_process
59565,GO:0003342,The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.,proepicardium development,biological_process
59566,GO:0003343,The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.,septum transversum development,biological_process
59567,GO:0003344,The process in which the anatomical structure of the pericardium is generated and organized.,pericardium morphogenesis,biological_process
59568,GO:0003345,The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.,proepicardium cell migration involved in pericardium morphogenesis,biological_process
59569,GO:0003346,The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.,epicardium-derived cell migration to the myocardium,biological_process
59570,GO:0003347,"A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.",epicardial cell to mesenchymal cell transition,biological_process
59571,GO:0003348,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.,cardiac endothelial cell differentiation,biological_process
59572,GO:0003349,The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.,epicardium-derived cardiac endothelial cell differentiation,biological_process
59573,GO:0003350,"The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.",pulmonary myocardium development,biological_process
59574,GO:0003351,"The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.",epithelial cilium movement involved in extracellular fluid movement,biological_process
59575,GO:0003352,"Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.",regulation of cilium movement,biological_process
59576,GO:0003353,"Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.",positive regulation of cilium movement,biological_process
59577,GO:0003354,"Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.",negative regulation of cilium movement,biological_process
59578,GO:0003355,"The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.",cilium movement involved in otolith formation,biological_process
59579,GO:0003356,"Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.",regulation of cilium beat frequency,biological_process
59580,GO:0003357,"The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.",noradrenergic neuron differentiation,biological_process
59581,GO:0003358,"The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",noradrenergic neuron development,biological_process
59582,GO:0003359,The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.,noradrenergic neuron fate commitment,biological_process
59583,GO:0003360,The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.,brainstem development,biological_process
59584,GO:0003363,"Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.",lamellipodium assembly involved in ameboidal cell migration,biological_process
59585,GO:0003365,The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.,establishment of cell polarity involved in ameboidal cell migration,biological_process
59586,GO:0003366,The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.,cell-matrix adhesion involved in ameboidal cell migration,biological_process
59587,GO:0003367,The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.,cell-cell adhesion involved in ameboidal cell migration,biological_process
59588,GO:0003369,The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.,establishment of cell polarity involved in mesendodermal cell migration,biological_process
59589,GO:0003370,The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.,cell-cell adhesion involved in mesendodermal cell migration,biological_process
59590,GO:0003371,"Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.",establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration,biological_process
59591,GO:0003376,"A G protein-coupled receptor signaling pathway initiated by sphingosine-1-phosphate binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",sphingosine-1-phosphate receptor signaling pathway,biological_process
59592,GO:0003379,The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.,establishment of cell polarity involved in gastrulation cell migration,biological_process
59593,GO:0003380,"Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.",establishment or maintenance of cytoskeleton polarity involved in gastrulation,biological_process
59594,GO:0003381,"The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.",epithelial cell morphogenesis involved in gastrulation,biological_process
59595,GO:0003382,The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.,epithelial cell morphogenesis,biological_process
59596,GO:0003383,The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.,apical constriction,biological_process
59597,GO:0003384,"The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.",apical constriction involved in gastrulation,biological_process
59598,GO:0003386,"The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.",amphid sensory organ development,biological_process
59599,GO:0003387,The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.,neuron differentiation involved in amphid sensory organ development,biological_process
59600,GO:0003388,"The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.",neuron development involved in amphid sensory organ development,biological_process
59601,GO:0003389,The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.,retrograde extension,biological_process
59602,GO:0003390,The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.,dendrite development by retrograde extension,biological_process
59603,GO:0003391,The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.,amphid sensory organ dendrite retrograde extension,biological_process
59604,GO:0003398,The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.,glial cell differentiation involved in amphid sensory organ development,biological_process
59605,GO:0003399,"The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.",cytoneme morphogenesis,biological_process
59606,GO:0003401,The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.,axis elongation,biological_process
59607,GO:0003403,The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.,optic vesicle formation,biological_process
59608,GO:0003404,The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.,optic vesicle morphogenesis,biological_process
59609,GO:0003405,The developmental growth that results in the lengthening of the optic vesicle in the posterior direction.,optic vesicle elongation,biological_process
59610,GO:0003406,"The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.",retinal pigment epithelium development,biological_process
59611,GO:0003407,The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.,neural retina development,biological_process
59612,GO:0003408,"The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.",optic cup formation involved in camera-type eye development,biological_process
59613,GO:0003409,The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.,optic cup structural organization,biological_process
59614,GO:0003410,A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis.,anterior rotation of the optic cup,biological_process
59615,GO:0003412,The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.,establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis,biological_process
59616,GO:0003413,The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.,chondrocyte differentiation involved in endochondral bone morphogenesis,biological_process
59617,GO:0003415,"The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.",chondrocyte hypertrophy,biological_process
59618,GO:0003416,The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.,endochondral bone growth,biological_process
59619,GO:0003417,The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.,growth plate cartilage development,biological_process
59620,GO:0003418,The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.,growth plate cartilage chondrocyte differentiation,biological_process
59621,GO:0003419,"The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.",growth plate cartilage chondrocyte proliferation,biological_process
59622,GO:0003420,"Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.",regulation of growth plate cartilage chondrocyte proliferation,biological_process
59623,GO:0003421,"The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.",growth plate cartilage axis specification,biological_process
59624,GO:0003422,The process in which the anatomical structures of growth plate cartilage are generated and organized.,growth plate cartilage morphogenesis,biological_process
59625,GO:0003423,The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.,growth plate cartilage chondrocyte division,biological_process
59626,GO:0003428,The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.,chondrocyte intercalation involved in growth plate cartilage morphogenesis,biological_process
59627,GO:0003429,The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.,growth plate cartilage chondrocyte morphogenesis,biological_process
59628,GO:0003430,"The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.",growth plate cartilage chondrocyte growth,biological_process
59629,GO:0003431,The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.,growth plate cartilage chondrocyte development,biological_process
59630,GO:0003433,The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.,chondrocyte development involved in endochondral bone morphogenesis,biological_process
59631,GO:0003674,"A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.",molecular_function,molecular_function
59632,GO:0003676,Binding to a nucleic acid.,nucleic acid binding,molecular_function
59633,GO:0003677,Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).,DNA binding,molecular_function
59634,GO:0003678,"Unwinding of a DNA helix, driven by ATP hydrolysis.",DNA helicase activity,molecular_function
59635,GO:0003680,Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins.,minor groove of adenine-thymine-rich DNA binding,molecular_function
59636,GO:0003681,Binding to DNA in a bent conformation.,bent DNA binding,molecular_function
59637,GO:0003682,"Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.",chromatin binding,molecular_function
59638,GO:0003684,Binding to damaged DNA.,damaged DNA binding,molecular_function
59639,GO:0003688,"Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.",DNA replication origin binding,molecular_function
59640,GO:0003689,"Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.",DNA clamp loader activity,molecular_function
59641,GO:0003690,Binding to double-stranded DNA.,double-stranded DNA binding,molecular_function
59642,GO:0003691,Binding to double-stranded telomere-associated DNA.,double-stranded telomeric DNA binding,molecular_function
59643,GO:0003692,"Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.",left-handed Z-DNA binding,molecular_function
59644,GO:0003693,"Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.",P-element binding,molecular_function
59645,GO:0003696,"Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.",satellite DNA binding,molecular_function
59646,GO:0003697,Binding to single-stranded DNA.,single-stranded DNA binding,molecular_function
59647,GO:0003700,"A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.",DNA-binding transcription factor activity,molecular_function
59648,GO:0003707,A nuclear receptor activity regulated by steroid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.,nuclear steroid receptor activity,molecular_function
59649,GO:0003711,"A molecular function that stimulates the elongation properties of the RNA polymerase during the elongation phase of transcription. A subclass of transcription elongation factors enable the transition from transcription initiation to elongation, while another class rescue stalled RNA polymerases.",transcription elongation factor activity,molecular_function
59650,GO:0003712,"A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A t...",transcription coregulator activity,molecular_function
59651,GO:0003713,"A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-depende...",transcription coactivator activity,molecular_function
59652,GO:0003714,"A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-depende...",transcription corepressor activity,molecular_function
59653,GO:0003720,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) using an internal RNA template that encodes the telomeric repeat sequence.,telomerase activity,molecular_function
59654,GO:0003723,Binding to an RNA molecule or a portion thereof.,RNA binding,molecular_function
59655,GO:0003724,"Unwinding of an RNA helix, driven by ATP hydrolysis.",RNA helicase activity,molecular_function
59656,GO:0003725,Binding to double-stranded RNA.,double-stranded RNA binding,molecular_function
59657,GO:0003726,"Catalysis of the reaction: adenosine + H2O = inosine + NH4+, in a double-stranded RNA molecule.",double-stranded RNA adenosine deaminase activity,molecular_function
59658,GO:0003727,Binding to single-stranded RNA.,single-stranded RNA binding,molecular_function
59659,GO:0003729,"Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.",mRNA binding,molecular_function
59660,GO:0003730,Binding to a 3' untranslated region of an mRNA molecule.,mRNA 3'-UTR binding,molecular_function
59661,GO:0003735,The action of a molecule that contributes to the structural integrity of the ribosome.,structural constituent of ribosome,molecular_function
59662,GO:0003743,Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.,translation initiation factor activity,molecular_function
59663,GO:0003746,Functions in chain elongation during polypeptide synthesis at the ribosome.,translation elongation factor activity,molecular_function
59664,GO:0003747,Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.,translation release factor activity,molecular_function
59665,GO:0003755,Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).,peptidyl-prolyl cis-trans isomerase activity,molecular_function
59666,GO:0003756,Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.,protein disulfide isomerase activity,molecular_function
59667,GO:0003774,"Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).",cytoskeletal motor activity,molecular_function
59668,GO:0003777,"A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.",microtubule motor activity,molecular_function
59669,GO:0003779,"Binding to monomeric or multimeric forms of actin, including actin filaments.",actin binding,molecular_function
59670,GO:0003785,"Binding to monomeric actin, also known as G-actin.",actin monomer binding,molecular_function
59671,GO:0003786,Binding to an actin filament along its length.,actin lateral binding,molecular_function
59672,GO:0003788,Binding to an actin monomer to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,actin monomer sequestering activity,molecular_function
59673,GO:0003789,"Binding to an actin subunit and promoting its dissociation from an actin filament by a local change in actin subunit conformation and orientation, and severing of filaments.",actin filament severing activity,molecular_function
59674,GO:0003796,Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.,lysozyme activity,molecular_function
59675,GO:0003810,"Catalysis of the reaction: L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4+. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.",protein-glutamine gamma-glutamyltransferase activity,molecular_function
59676,GO:0003823,"Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell.",antigen binding,molecular_function
59677,GO:0003824,"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.",catalytic activity,molecular_function
59678,GO:0003825,"Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.","alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity",molecular_function
59679,GO:0003827,Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H+ + UDP.,"alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity",molecular_function
59680,GO:0003828,Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",molecular_function
59681,GO:0003829,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R. This reaction is the addition of N-acetyl-alpha-D-glucosamine to the core 1 structure of O-glycans forming core 2.,"beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity",molecular_function
59682,GO:0003830,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.,"beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",molecular_function
59683,GO:0003831,Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.,"beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity",molecular_function
59684,GO:0003832,Catalysis of the reaction: beta-alanyl-dopamine + H2O = dopamine + beta-alanine.,beta-alanyl-dopamine hydrolase activity,molecular_function
59685,GO:0003833,"Catalysis of the synthesis of beta-alanyl amine conjugate from a precursor biogenic amine, such as dopamine or histamine.",beta-alanyl amine synthase activity,molecular_function
59686,GO:0003834,Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.,"beta-carotene 15,15'-dioxygenase activity",molecular_function
59687,GO:0003835,Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactoside = N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H+.,"beta-galactoside alpha-2,6-sialyltransferase activity",molecular_function
59688,GO:0003836,Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.,"beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",molecular_function
59689,GO:0003837,Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH4+.,beta-ureidopropionase activity,molecular_function
59690,GO:0003838,Catalysis of the reaction: S-adenosyl-L-methionine + zymosterol = fecosterol + H+ + S-adenosyl-L-homocysteine.,sterol 24-C-methyltransferase activity,molecular_function
59691,GO:0003839,Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.,gamma-glutamylcyclotransferase activity,molecular_function
59692,GO:0003841,"Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.",1-acylglycerol-3-phosphate O-acyltransferase activity,molecular_function
59693,GO:0003842,L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+.,L-glutamate gamma-semialdehyde dehydrogenase (NAD+) activity,molecular_function
59694,GO:0003843,Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).,"1,3-beta-D-glucan synthase activity",molecular_function
59695,GO:0003844,Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.,"1,4-alpha-glucan branching enzyme activity",molecular_function
59696,GO:0003846,Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.,2-acylglycerol O-acyltransferase activity,molecular_function
59697,GO:0003847,Catalysis of the reaction: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H+.,1-alkyl-2-acetylglycerophosphocholine esterase activity,molecular_function
59698,GO:0003848,"Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H+.",2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity,molecular_function
59699,GO:0003849,Catalysis of the reaction: D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.,3-deoxy-7-phosphoheptulonate synthase activity,molecular_function
59700,GO:0003850,Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.,2-deoxyglucose-6-phosphatase activity,molecular_function
59701,GO:0003851,Catalysis of the reaction: N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP.,N-acylsphingosine galactosyltransferase activity,molecular_function
59702,GO:0003852,Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H+.,2-isopropylmalate synthase activity,molecular_function
59703,GO:0003853,Catalysis of the reaction: Catalysis of the reaction: a short-chain 2-methyl fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a short-chain (2E)-2-methyl-2-enoyl-CoA + reduced [electron-transfer flavoprotein].,short-chain 2-methyl fatty acyl-CoA dehydrogenase activity,molecular_function
59704,GO:0003854,Catalysis of the reaction: a 3-beta-hydroxy-Delta(5)-steroid + NAD+ = a 3-oxo-Delta(5)-steroid + NADH + H+. Also acts on on 3-beta-hydroxypregn-5-en-20-one to form progesterone.,3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity,molecular_function
59705,GO:0003855,Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H2O.,3-dehydroquinate dehydratase activity,molecular_function
59706,GO:0003856,Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.,3-dehydroquinate synthase activity,molecular_function
59707,GO:0003857,Catalysis of the reaction: a (3S)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + NADH + H+.,(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity,molecular_function
59708,GO:0003858,Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.,3-hydroxybutyrate dehydrogenase activity,molecular_function
59709,GO:0003860,Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.,3-hydroxyisobutyryl-CoA hydrolase activity,molecular_function
59710,GO:0003861,"Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.",3-isopropylmalate dehydratase activity,molecular_function
59711,GO:0003862,"Catalysis of the reaction: (2R,3S)-3-isopropylmalate + NAD+ = 4-methyl-2-oxopentanoate + CO2 + NADH.",3-isopropylmalate dehydrogenase activity,molecular_function
59712,GO:0003863,"Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H+ = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2. Also acts on 4-methyl-2-oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on the 2-oxo acids that derive from the action of transaminases on valine, leucine and isoleucine.",branched-chain 2-oxo acid dehydrogenase activity,molecular_function
59713,GO:0003864,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.",3-methyl-2-oxobutanoate hydroxymethyltransferase activity,molecular_function
59714,GO:0003865,Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.,3-oxo-5-alpha-steroid 4-dehydrogenase activity,molecular_function
59715,GO:0003866,Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.,3-phosphoshikimate 1-carboxyvinyltransferase activity,molecular_function
59716,GO:0003868,Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.,4-hydroxyphenylpyruvate dioxygenase activity,molecular_function
59717,GO:0003870,Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA.,5-aminolevulinate synthase activity,molecular_function
59718,GO:0003871,Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.,5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity,molecular_function
59719,GO:0003872,"Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.",6-phosphofructokinase activity,molecular_function
59720,GO:0003873,"Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H+.",6-phosphofructo-2-kinase activity,molecular_function
59721,GO:0003874,"Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H+ + triphosphate.",6-pyruvoyltetrahydropterin synthase activity,molecular_function
59722,GO:0003875,"Catalysis of the reactions: H2O + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] = ADP-D-ribose + L-arginyl-[protein], and H2O + N(omega)-(ADP-D-ribosyl)-L-arginine = ADP-D-ribose + L-arginine.",ADP-ribosylarginine-[protein] hydrolase activity,molecular_function
59723,GO:0003876,Catalysis of the reaction: AMP + H2O = IMP + NH4+.,AMP deaminase activity,molecular_function
59724,GO:0003877,"Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.",ATP:ADP adenylyltransferase activity,molecular_function
59725,GO:0003878,Catalysis of the reaction: acetyl-CoA + ADP + H+ + oxaloacetate + phosphate = ATP + citrate + CoA.,ATP citrate synthase activity,molecular_function
59726,GO:0003879,Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.,ATP phosphoribosyltransferase activity,molecular_function
59727,GO:0003880,Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.,protein C-terminal carboxyl O-methyltransferase activity,molecular_function
59728,GO:0003881,Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H+.,CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity,molecular_function
59729,GO:0003882,Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.,CDP-diacylglycerol-serine O-phosphatidyltransferase activity,molecular_function
59730,GO:0003883,Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.,CTP synthase activity,molecular_function
59731,GO:0003884,Catalysis of the reaction: a D-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4+.,D-amino-acid oxidase activity,molecular_function
59732,GO:0003885,"Catalysis of the reaction: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H+.","D-arabinono-1,4-lactone oxidase activity",molecular_function
59733,GO:0003886,Catalysis of the reaction: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteine.,DNA (cytosine-5-)-methyltransferase activity,molecular_function
59734,GO:0003887,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.,DNA-directed DNA polymerase activity,molecular_function
59735,GO:0003899,"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.",DNA-directed RNA polymerase activity,molecular_function
59736,GO:0003904,Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.,deoxyribodipyrimidine photo-lyase activity,molecular_function
59737,GO:0003905,"Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.",alkylbase DNA N-glycosylase activity,molecular_function
59738,GO:0003906,"Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).",DNA-(apurinic or apyrimidinic site) endonuclease activity,molecular_function
59739,GO:0003908,Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.,methylated-DNA-[protein]-cysteine S-methyltransferase activity,molecular_function
59740,GO:0003909,Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.,DNA ligase activity,molecular_function
59741,GO:0003910,Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).,DNA ligase (ATP) activity,molecular_function
59742,GO:0003911,Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).,DNA ligase (NAD+) activity,molecular_function
59743,GO:0003912,Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.,DNA nucleotidylexotransferase activity,molecular_function
59744,GO:0003913,Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.,DNA photolyase activity,molecular_function
59745,GO:0003914,Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.,DNA (6-4) photolyase activity,molecular_function
59746,GO:0003916,"Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.",DNA topoisomerase activity,molecular_function
59747,GO:0003917,Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.,"DNA topoisomerase type I (single strand cut, ATP-independent) activity",molecular_function
59748,GO:0003918,"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.","DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity",molecular_function
59749,GO:0003919,Catalysis of the reaction: ATP + FMN = diphosphate + FAD.,FMN adenylyltransferase activity,molecular_function
59750,GO:0003920,Catalysis of the reaction: IMP + NADP+ + NH4 = GMP + 2 H+ + NADPH.,GMP reductase activity,molecular_function
59751,GO:0003921,Catalysis of the reaction: ATP + XMP + NH4+ = AMP + diphosphate + GMP + 2H+.,GMP synthase activity,molecular_function
59752,GO:0003922,Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+.,GMP synthase (glutamine-hydrolyzing) activity,molecular_function
59753,GO:0003923,"Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.",GPI-anchor transamidase activity,molecular_function
59754,GO:0003924,Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.,GTPase activity,molecular_function
59755,GO:0003925,"A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).",G protein activity,molecular_function
59756,GO:0003933,"Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.",GTP cyclohydrolase activity,molecular_function
59757,GO:0003934,"Catalysis of the reaction: GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H+.",GTP cyclohydrolase I activity,molecular_function
59758,GO:0003935,"Catalysis of the reaction: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H+ + 2 phosphate.",GTP cyclohydrolase II activity,molecular_function
59759,GO:0003937,Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.,IMP cyclohydrolase activity,molecular_function
59760,GO:0003938,Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.,IMP dehydrogenase activity,molecular_function
59761,GO:0003939,"Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.",L-iditol 2-dehydrogenase (NAD+) activity,molecular_function
59762,GO:0003940,Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate. Can also hydrolyze alpha-L-iduronosidic linkages in heparan sulfate.,L-iduronidase activity,molecular_function
59763,GO:0003941,Catalysis of the reaction: L-serine = pyruvate + NH4+.,L-serine ammonia-lyase activity,molecular_function
59764,GO:0003942,Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.,N-acetyl-gamma-glutamyl-phosphate reductase (NADP+) activity,molecular_function
59765,GO:0003943,Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.,N-acetylgalactosamine-4-sulfatase activity,molecular_function
59766,GO:0003944,Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.,N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity,molecular_function
59767,GO:0003945,Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.,N-acetyllactosamine synthase activity,molecular_function
59768,GO:0003947,Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.,(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity,molecular_function
59769,GO:0003948,Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H+.,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity,molecular_function
59770,GO:0003949,Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.,1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity,molecular_function
59771,GO:0003950,Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,NAD+ poly-ADP-ribosyltransferase activity,molecular_function
59772,GO:0003951,Catalysis of the reaction: ATP + NAD+ = ADP + H+ + NADP+.,NAD+ kinase activity,molecular_function
59773,GO:0003952,Catalysis of the reaction: deamido-NAD+ + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD+ + H+.,NAD+ synthase (glutamine-hydrolyzing) activity,molecular_function
59774,GO:0003953,Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+.,NAD+ nucleosidase activity,molecular_function
59775,GO:0003954,Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.,NADH dehydrogenase activity,molecular_function
59776,GO:0003955,Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a quinol.,NAD(P)H dehydrogenase (quinone) activity,molecular_function
59777,GO:0003957,Catalysis of the reaction: NADPH + NAD+ = NADP+ + NADH.,NAD(P)+ transhydrogenase (Si-specific) activity,molecular_function
59778,GO:0003958,Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.,NADPH-hemoprotein reductase activity,molecular_function
59779,GO:0003959,Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.,NADPH dehydrogenase activity,molecular_function
59780,GO:0003960,"Catalysis of the reaction: 2 a quinone + NADPH + H+ = 2 a 1,4-benzosemiquinone + NADP+.",quinone reductase (NADPH) activity,molecular_function
59781,GO:0003961,"Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.",O-acetylhomoserine aminocarboxypropyltransferase activity,molecular_function
59782,GO:0003962,"Catalysis of the reaction: L-cysteine + O-succinyl-L-homoserine = H+ + L,L-cystathionine + succinate.",cystathionine gamma-synthase activity,molecular_function
59783,GO:0003963,"Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.",RNA-3'-phosphate cyclase activity,molecular_function
59784,GO:0003964,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.,RNA-directed DNA polymerase activity,molecular_function
59785,GO:0003968,"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.",RNA-directed RNA polymerase activity,molecular_function
59786,GO:0003972,Catalysis of the reaction: ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m = (ribonucleotide)n+m + AMP + diphosphate.,RNA ligase (ATP) activity,molecular_function
59787,GO:0003973,Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + H2O2.,(S)-2-hydroxy-acid oxidase activity,molecular_function
59788,GO:0003974,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.,UDP-N-acetylglucosamine 4-epimerase activity,molecular_function
59789,GO:0003975,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.,UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity,molecular_function
59790,GO:0003976,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.,UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity,molecular_function
59791,GO:0003977,Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.,UDP-N-acetylglucosamine diphosphorylase activity,molecular_function
59792,GO:0003978,Catalysis of the reaction: UDP-glucose = UDP-galactose.,UDP-glucose 4-epimerase activity,molecular_function
59793,GO:0003979,Catalysis of the reaction: H2O + 2 NAD+ + UDP-alpha-D-glucose = 3 H+ + 2 NADH + UDP-alpha-D-glucuronate.,UDP-glucose 6-dehydrogenase activity,molecular_function
59794,GO:0003980,Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.,UDP-glucose:glycoprotein glucosyltransferase activity,molecular_function
59795,GO:0003983,Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.,UTP:glucose-1-phosphate uridylyltransferase activity,molecular_function
59796,GO:0003984,Catalysis of the reaction: H+ + 2 pyruvate = (2S)-2-acetolactate + CO2. Can also convert 2-oxobutanoate and pyruvate to (S)-2-ethyl-2-hydroxy-3-oxobutanoate.,acetolactate synthase activity,molecular_function
59797,GO:0003985,Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.,acetyl-CoA C-acetyltransferase activity,molecular_function
59798,GO:0003986,Catalysis of the reaction: acetyl-CoA + H2O = acetate + CoA + H+.,acetyl-CoA hydrolase activity,molecular_function
59799,GO:0003987,Catalysis of the reaction: acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.,acetyl-CoA synthetase activity,molecular_function
59800,GO:0003988,Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.,acetyl-CoA C-acyltransferase activity,molecular_function
59801,GO:0003989,Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.,acetyl-CoA carboxylase activity,molecular_function
59802,GO:0003990,Catalysis of the reaction: acetylcholine + H2O = choline + acetate.,acetylcholinesterase activity,molecular_function
59803,GO:0003991,Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.,acetylglutamate kinase activity,molecular_function
59804,GO:0003992,Catalysis of the reaction: N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.,N2-acetyl-L-ornithine:2-oxoglutarate 5-transaminase activity,molecular_function
59805,GO:0003993,"Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.",acid phosphatase activity,molecular_function
59806,GO:0003994,"Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.",aconitate hydratase activity,molecular_function
59807,GO:0003995,"Catalysis of the reaction: a 2,3-saturated acyl-CoA + H+ oxidized [electron-transfer flavoprotein] = a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].",acyl-CoA dehydrogenase activity,molecular_function
59808,GO:0003997,"Catalysis of the reaction: a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.",acyl-CoA oxidase activity,molecular_function
59809,GO:0003998,Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.,acylphosphatase activity,molecular_function
59810,GO:0003999,Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.,adenine phosphoribosyltransferase activity,molecular_function
59811,GO:0004000,Catalysis of the reaction: adenosine + H2O = inosine + NH4+.,adenosine deaminase activity,molecular_function
59812,GO:0004001,Catalysis of the reaction: ATP + adenosine = ADP + AMP.,adenosine kinase activity,molecular_function
59813,GO:0004013,Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.,adenosylhomocysteinase activity,molecular_function
59814,GO:0004014,Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2.,adenosylmethionine decarboxylase activity,molecular_function
59815,GO:0004015,"Catalysis of the reaction: (8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = S-adenosyl-4-methylsulfanyl-2-oxobutanoate + (7R,8S)-7,8-diammoniononanoate.",S-adenosyl-L-methionine:8-amino-7-oxononanoate transaminase activity,molecular_function
59816,GO:0004016,"Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.",adenylate cyclase activity,molecular_function
59817,GO:0004017,Catalysis of the reaction: ATP + AMP = 2 ADP.,AMP kinase activity,molecular_function
59818,GO:0004018,"Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.","N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity",molecular_function
59819,GO:0004019,"Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H+ + phosphate.",adenylosuccinate synthase activity,molecular_function
59820,GO:0004020,Catalysis of the reaction: adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H+.,adenylylsulfate kinase activity,molecular_function
59821,GO:0004021,Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.,L-alanine:2-oxoglutarate transaminase activity,molecular_function
59822,GO:0004022,Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.,alcohol dehydrogenase (NAD+) activity,molecular_function
59823,GO:0004026,Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.,alcohol O-acetyltransferase activity,molecular_function
59824,GO:0004027,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.",alcohol sulfotransferase activity,molecular_function
59825,GO:0004028,Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.,3-chloroallyl aldehyde dehydrogenase activity,molecular_function
59826,GO:0004029,Catalysis of the reaction: an aldehyde + H2O + NAD+ = a carboxylate + 2 H+ + NADH.,aldehyde dehydrogenase (NAD+) activity,molecular_function
59827,GO:0004030,Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.,aldehyde dehydrogenase [NAD(P)+] activity,molecular_function
59828,GO:0004031,Catalysis of the reaction: an aldehyde + O2 + H2O = a carboxylate + H2O2 + H+.,aldehyde oxidase activity,molecular_function
59829,GO:0004032,Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.,aldose reductase (NADPH) activity,molecular_function
59830,GO:0004034,"Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.",aldose 1-epimerase activity,molecular_function
59831,GO:0004035,"Catalysis of the reaction: a phosphate monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.",alkaline phosphatase activity,molecular_function
59832,GO:0004037,Catalysis of the reaction: allantoate + H2O = (S)-ureidoglycolate + urea.,allantoicase activity,molecular_function
59833,GO:0004038,Catalysis of the reaction: allantoin + H2O = allantoate.,allantoinase activity,molecular_function
59834,GO:0004039,Catalysis of the reaction: H2O + 3 H+ + urea-1-carboxylate = 2 CO2 + 2 NH4.,allophanate hydrolase activity,molecular_function
59835,GO:0004040,Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4+.,amidase activity,molecular_function
59836,GO:0004042,Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H+.,"L-glutamate N-acetyltransferase activity, acting on acetyl-CoA as donor",molecular_function
59837,GO:0004043,Catalysis of the reaction: (S)-2-amino-6-oxohexanoate + NAD(P)+ + H2O = L-2-aminoadipate + NAD(P)H + 2 H+.,L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity,molecular_function
59838,GO:0004044,Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.,amidophosphoribosyltransferase activity,molecular_function
59839,GO:0004045,Catalysis of the reaction: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H+.,peptidyl-tRNA hydrolase activity,molecular_function
59840,GO:0004046,Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.,aminoacylase activity,molecular_function
59841,GO:0004047,"Catalysis of the reaction: N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4+.",aminomethyltransferase activity,molecular_function
59842,GO:0004048,Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.,anthranilate phosphoribosyltransferase activity,molecular_function
59843,GO:0004049,Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.,anthranilate synthase activity,molecular_function
59844,GO:0004050,"Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs).",apyrase activity,molecular_function
59845,GO:0004051,"Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = H2O + leukotriene A4.",arachidonate 5-lipoxygenase activity,molecular_function
59846,GO:0004052,"Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.",arachidonate 12(S)-lipoxygenase activity,molecular_function
59847,GO:0004053,Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.,arginase activity,molecular_function
59848,GO:0004054,Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H+.,arginine kinase activity,molecular_function
59849,GO:0004055,Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.,argininosuccinate synthase activity,molecular_function
59850,GO:0004056,Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.,argininosuccinate lyase activity,molecular_function
59851,GO:0004057,Catalysis of the reaction: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = H+ + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg).,arginyl-tRNA--protein transferase activity,molecular_function
59852,GO:0004058,Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.,aromatic-L-amino-acid decarboxylase activity,molecular_function
59853,GO:0004059,Catalysis of the reaction: a 2-arylethylamine + acetyl-CoA = an N-acetyl-2-arylethylamine + CoA + H+.,aralkylamine N-acetyltransferase activity,molecular_function
59854,GO:0004060,Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.,arylamine N-acetyltransferase activity,molecular_function
59855,GO:0004061,Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.,arylformamidase activity,molecular_function
59856,GO:0004062,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.",aryl sulfotransferase activity,molecular_function
59857,GO:0004063,Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.,aryldialkylphosphatase activity,molecular_function
59858,GO:0004064,Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.,arylesterase activity,molecular_function
59859,GO:0004065,Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.,arylsulfatase activity,molecular_function
59860,GO:0004066,Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.,asparagine synthase (glutamine-hydrolyzing) activity,molecular_function
59861,GO:0004067,Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH4+.,asparaginase activity,molecular_function
59862,GO:0004068,Catalysis of the reaction: L-aspartate = beta-alanine + CO2.,aspartate 1-decarboxylase activity,molecular_function
59863,GO:0004069,Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,L-aspartate:2-oxoglutarate transaminase activity,molecular_function
59864,GO:0004070,Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H+ + phosphate.,aspartate carbamoyltransferase activity,molecular_function
59865,GO:0004071,Catalysis of the reaction: ATP + L-aspartate + NH4+ = AMP + diphosphate + L-asparagine.,aspartate-ammonia ligase activity,molecular_function
59866,GO:0004072,Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H+.,aspartate kinase activity,molecular_function
59867,GO:0004073,Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP+ + phosphate = 4-phospho-L-aspartate + H+ + NADPH.,aspartate-semialdehyde dehydrogenase (NADP+) activity,molecular_function
59868,GO:0004074,Catalysis of the reaction: bilirubin IXalpha + NAD(P)+ = biliverdin IXalpha + NAD(P)H + H+.,biliverdin reductase [NAD(P)H] activity,molecular_function
59869,GO:0004075,Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.,biotin carboxylase activity,molecular_function
59870,GO:0004076,"Catalysis of the reaction: (4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = [sulfur carrier]-H + biotin + 2 5'-deoxyadenosine + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin].",biotin synthase activity,molecular_function
59871,GO:0004077,Catalysis of the reaction: ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H+ + N(6)-biotinyl-L-lysyl-[protein].,biotin--[biotin carboxyl-carrier protein] ligase activity,molecular_function
59872,GO:0004081,"Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.",bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity,molecular_function
59873,GO:0004082,"Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.",bisphosphoglycerate mutase activity,molecular_function
59874,GO:0004084,"Catalysis of the reaction: a branched-chain amino acid (L-leucine, L-isoleucine and L-valine) + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.",branched-chain-amino-acid:2-oxoglutarate transaminase activity,molecular_function
59875,GO:0004087,Catalysis of the reaction: 2 ATP + hydrogencarbonate + NH4+ = 2 ADP + carbamoyl phosphate + 2 H+ + phosphate.,carbamoyl-phosphate synthase (ammonia) activity,molecular_function
59876,GO:0004088,Catalysis of the reaction: hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H+.,carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity,molecular_function
59877,GO:0004089,Catalysis of the reaction: hydrogencarbonate + H+ = CO2 + H2O.,carbonate dehydratase activity,molecular_function
59878,GO:0004090,Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.,carbonyl reductase (NADPH) activity,molecular_function
59879,GO:0004092,Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.,carnitine O-acetyltransferase activity,molecular_function
59880,GO:0004095,Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.,carnitine O-palmitoyltransferase activity,molecular_function
59881,GO:0004096,Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.,catalase activity,molecular_function
59882,GO:0004097,"Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones.",catechol oxidase activity,molecular_function
59883,GO:0004098,Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.,cerebroside-sulfatase activity,molecular_function
59884,GO:0004099,Catalysis of the reaction: chitin + H2O = chitosan + acetate.,chitin deacetylase activity,molecular_function
59885,GO:0004100,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).,chitin synthase activity,molecular_function
59886,GO:0004102,Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.,choline O-acetyltransferase activity,molecular_function
59887,GO:0004103,Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H+.,choline kinase activity,molecular_function
59888,GO:0004104,Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.,cholinesterase activity,molecular_function
59889,GO:0004105,Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.,choline-phosphate cytidylyltransferase activity,molecular_function
59890,GO:0004106,Catalysis of the reaction: chorismate = prephenate.,chorismate mutase activity,molecular_function
59891,GO:0004107,Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.,chorismate synthase activity,molecular_function
59892,GO:0004109,Catalysis of the reaction: coproporphyrinogen III + 2 H+ + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX.,coproporphyrinogen oxidase activity,molecular_function
59893,GO:0004110,Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.,corticosteroid side-chain-isomerase activity,molecular_function
59894,GO:0004111,Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H+.,creatine kinase activity,molecular_function
59895,GO:0004112,Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.,cyclic-nucleotide phosphodiesterase activity,molecular_function
59896,GO:0004113,"Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.","2',3'-cyclic-nucleotide 3'-phosphodiesterase activity",molecular_function
59897,GO:0004114,"Catalysis of the reaction: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate.","3',5'-cyclic-nucleotide phosphodiesterase activity",molecular_function
59898,GO:0004115,"Catalysis of the reaction: 3',5'-cyclic AMP + H2O = AMP + H+.","3',5'-cyclic-AMP phosphodiesterase activity",molecular_function
59899,GO:0004117,"Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.","calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity",molecular_function
59900,GO:0004118,"Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.","3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity",molecular_function
59901,GO:0004119,"Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.","3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity",molecular_function
59902,GO:0004122,Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.,cystathionine beta-synthase activity,molecular_function
59903,GO:0004123,Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.,cystathionine gamma-lyase activity,molecular_function
59904,GO:0004124,Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.,cysteine synthase activity,molecular_function
59905,GO:0004125,Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.,L-seryl-tRNA(Sec) selenium transferase activity,molecular_function
59906,GO:0004126,Catalysis of the reaction: cytidine + H+ + H2O = uridine + NH4 and deoxycytidine + H+ + H2O = deoxyuridine + NH4+.,cytidine deaminase activity,molecular_function
59907,GO:0004128,Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NAD(P)H = 2 Fe(II)-[cytochrome b5] + NAD(P)+ + H+.,"cytochrome-b5 reductase activity, acting on NAD(P)H",molecular_function
59908,GO:0004129,Catalysis of the reaction: 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out).,cytochrome-c oxidase activity,molecular_function
59909,GO:0004130,Catalysis of the reaction: 2 ferrocytochrome c + H2O2 = 2 ferricytochrome c + 2 H2O.,cytochrome-c peroxidase activity,molecular_function
59910,GO:0004131,Catalysis of the reaction: cytosine + H2O = uracil + NH4+.,cytosine deaminase activity,molecular_function
59911,GO:0004132,Catalysis of the reaction: dCMP + H2O = dUMP + NH4+.,dCMP deaminase activity,molecular_function
59912,GO:0004134,"Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.",4-alpha-glucanotransferase activity,molecular_function
59913,GO:0004135,Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.,"amylo-alpha-1,6-glucosidase activity",molecular_function
59914,GO:0004136,Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.,deoxyadenosine kinase activity,molecular_function
59915,GO:0004137,Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.,deoxycytidine kinase activity,molecular_function
59916,GO:0004138,Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H+.,deoxyguanosine kinase activity,molecular_function
59917,GO:0004139,Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.,deoxyribose-phosphate aldolase activity,molecular_function
59918,GO:0004140,Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+.,dephospho-CoA kinase activity,molecular_function
59919,GO:0004141,"Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO2 = ADP + dethiobiotin + 4 H+ + phosphate.",dethiobiotin synthase activity,molecular_function
59920,GO:0004142,"Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.",diacylglycerol cholinephosphotransferase activity,molecular_function
59921,GO:0004143,"Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+.",ATP-dependent diacylglycerol kinase activity,molecular_function
59922,GO:0004144,"Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.",diacylglycerol O-acyltransferase activity,molecular_function
59923,GO:0004145,"Catalysis of the reaction: an alkane-alpha,omega-diamine + acetyl-CoA = an N-acetylalkane-alpha,omega-diamine + CoA + H+.",diamine N-acetyltransferase activity,molecular_function
59924,GO:0004146,"Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.",dihydrofolate reductase activity,molecular_function
59925,GO:0004148,Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD+ = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H+.,dihydrolipoyl dehydrogenase (NADH) activity,molecular_function
59926,GO:0004149,Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA.,dihydrolipoyllysine-residue succinyltransferase activity,molecular_function
59927,GO:0004150,"Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.",dihydroneopterin aldolase activity,molecular_function
59928,GO:0004151,Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.,dihydroorotase activity,molecular_function
59929,GO:0004152,Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.,dihydroorotate dehydrogenase activity,molecular_function
59930,GO:0004153,"Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH4+.",dihydropterin deaminase activity,molecular_function
59931,GO:0004154,"Catalysis of the reaction: a 7,8-dihydropteridine compound + O2 = an oxidized 7,8-dihydropteridine compound + H2O2. Specific substrates and their fully oxidized products include: 7,8-dihydropteridin/pterin, 7,8-dihydrobiopterin/biopterin, 7,8-dihydroxanthopterin/xanthopterin and sepiapterin/oxidized sepiapterin.",dihydropterin oxidase activity,molecular_function
59932,GO:0004155,"Catalysis of the reaction: NAD(P)+ + 5,6,7,8-tetrahydropteridine = NAD(P)H + H+ + 6,7-dihydropteridine.","6,7-dihydropteridine reductase activity",molecular_function
59933,GO:0004156,"Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.",dihydropteroate synthase activity,molecular_function
59934,GO:0004157,"Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.",dihydropyrimidinase activity,molecular_function
59935,GO:0004159,"Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.",dihydropyrimidine dehydrogenase (NAD+) activity,molecular_function
59936,GO:0004160,"Catalysis of the reaction: (2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.",dihydroxy-acid dehydratase activity,molecular_function
59937,GO:0004161,Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = (2E)-geranyl diphosphate + diphosphate.,dimethylallyltranstransferase activity,molecular_function
59938,GO:0004163,Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.,diphosphomevalonate decarboxylase activity,molecular_function
59939,GO:0004164,Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H+ + 3 S-adenosyl-L-homocysteine.,diphthine synthase activity,molecular_function
59940,GO:0004165,Catalysis of the reactions: a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA or a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.,delta(3)-delta(2)-enoyl-CoA isomerase activity,molecular_function
59941,GO:0004166,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.,dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity,molecular_function
59942,GO:0004167,"Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.",dopachrome isomerase activity,molecular_function
59943,GO:0004168,Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.,dolichol kinase activity,molecular_function
59944,GO:0004169,Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.,dolichyl-phosphate-mannose-protein mannosyltransferase activity,molecular_function
59945,GO:0004170,Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate.,dUTP diphosphatase activity,molecular_function
59946,GO:0004173,Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.,ecdysone O-acyltransferase activity,molecular_function
59947,GO:0004174,Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].,electron-transferring-flavoprotein dehydrogenase activity,molecular_function
59948,GO:0004175,"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.",endopeptidase activity,molecular_function
59949,GO:0004176,"Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.",ATP-dependent peptidase activity,molecular_function
59950,GO:0004177,Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.,aminopeptidase activity,molecular_function
59951,GO:0004180,Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.,carboxypeptidase activity,molecular_function
59952,GO:0004181,"Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metallocarboxypeptidase activity,molecular_function
59953,GO:0004185,Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).,serine-type carboxypeptidase activity,molecular_function
59954,GO:0004190,"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.",aspartic-type endopeptidase activity,molecular_function
59955,GO:0004197,"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.",cysteine-type endopeptidase activity,molecular_function
59956,GO:0004198,"Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.",calcium-dependent cysteine-type endopeptidase activity,molecular_function
59957,GO:0004222,"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metalloendopeptidase activity,molecular_function
59958,GO:0004230,Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,glutamyl aminopeptidase activity,molecular_function
59959,GO:0004239,Catalysis of the release of N-terminal initiator methionine from peptides.,initiator methionyl aminopeptidase activity,molecular_function
59960,GO:0004252,"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).",serine-type endopeptidase activity,molecular_function
59961,GO:0004298,Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.,threonine-type endopeptidase activity,molecular_function
59962,GO:0004300,"Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a enoyl-CoA + H2O. This reaction usually occurs in the reverse direction, leading to the reduction of the double bound of enoyl-CoA in position 2 or 3. Specific reactions catalyzed include: a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O and a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O.",enoyl-CoA hydratase activity,molecular_function
59963,GO:0004301,Catalysis of the reaction: an epoxide + H2O = an ethanediol.,epoxide hydrolase activity,molecular_function
59964,GO:0004303,Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor.,estradiol 17-beta-dehydrogenase [NAD(P)+] activity,molecular_function
59965,GO:0004304,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.",estrone sulfotransferase activity,molecular_function
59966,GO:0004305,Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H+ + phosphoethanolamine.,ethanolamine kinase activity,molecular_function
59967,GO:0004306,Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.,ethanolamine-phosphate cytidylyltransferase activity,molecular_function
59968,GO:0004307,"Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.",ethanolaminephosphotransferase activity,molecular_function
59969,GO:0004308,"Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.",exo-alpha-sialidase activity,molecular_function
59970,GO:0004309,Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.,exopolyphosphatase activity,molecular_function
59971,GO:0004311,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate.",geranylgeranyl diphosphate synthase activity,molecular_function
59972,GO:0004312,Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.,fatty acid synthase activity,molecular_function
59973,GO:0004313,Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein].,[acyl-carrier-protein] S-acetyltransferase activity,molecular_function
59974,GO:0004314,Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].,[acyl-carrier-protein] S-malonyltransferase activity,molecular_function
59975,GO:0004315,Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].,3-oxoacyl-[acyl-carrier-protein] synthase activity,molecular_function
59976,GO:0004316,Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.,3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity,molecular_function
59977,GO:0004318,"Catalysis of the reaction: a 2,3-saturated acyl-[ACP] + NAD+ = a (2E)-enoyl-[ACP] + H+ + NADH.",enoyl-[acyl-carrier-protein] reductase (NADH) activity,molecular_function
59978,GO:0004321,Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.,fatty-acyl-CoA synthase activity,molecular_function
59979,GO:0004322,Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.,ferroxidase activity,molecular_function
59980,GO:0004324,Catalysis of the reaction: 2 reduced [2Fe-2S]-[ferredoxin] + NADP+ + H+ = 2 oxidized [2Fe-2S]-[ferredoxin] + NADPH.,ferredoxin-NADP+ reductase activity,molecular_function
59981,GO:0004325,Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.,protoporphyrin ferrochelatase activity,molecular_function
59982,GO:0004326,Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).,tetrahydrofolylpolyglutamate synthase activity,molecular_function
59983,GO:0004328,Catalysis of the reaction: formamide + H2O = formate + NH4.,formamidase activity,molecular_function
59984,GO:0004329,Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.,formate-tetrahydrofolate ligase activity,molecular_function
59985,GO:0004331,"Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.","fructose-2,6-bisphosphate 2-phosphatase activity",molecular_function
59986,GO:0004332,"Catalysis of the reaction: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.",fructose-bisphosphate aldolase activity,molecular_function
59987,GO:0004333,Catalysis of the reaction: (S)-malate = fumarate + H2O.,fumarate hydratase activity,molecular_function
59988,GO:0004334,Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H+.,fumarylacetoacetase activity,molecular_function
59989,GO:0004335,Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H+.,galactokinase activity,molecular_function
59990,GO:0004336,Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.,galactosylceramidase activity,molecular_function
59991,GO:0004337,"Catalysis of the reaction: (2E)-geranyl diphosphate + isopentenyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate.","(2E,6E)-farnesyl diphosphate synthase activity",molecular_function
59992,GO:0004338,"Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.","glucan exo-1,3-beta-glucosidase activity",molecular_function
59993,GO:0004339,Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.,"glucan 1,4-alpha-glucosidase activity",molecular_function
59994,GO:0004340,Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.,glucokinase activity,molecular_function
59995,GO:0004341,"Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.",gluconolactonase activity,molecular_function
59996,GO:0004342,Catalysis of the reaction: D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4.,glucosamine-6-phosphate deaminase activity,molecular_function
59997,GO:0004343,Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H+.,glucosamine 6-phosphate N-acetyltransferase activity,molecular_function
59998,GO:0004344,"Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.",glucose dehydrogenase activity,molecular_function
59999,GO:0004345,"Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.",glucose-6-phosphate dehydrogenase activity,molecular_function
60000,GO:0004346,Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.,glucose-6-phosphatase activity,molecular_function
60001,GO:0004347,Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate.,glucose-6-phosphate isomerase activity,molecular_function
60002,GO:0004348,Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.,glucosylceramidase activity,molecular_function
60003,GO:0004349,Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H+.,glutamate 5-kinase activity,molecular_function
60004,GO:0004350,Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP+ + phosphate = L-glutamyl 5-phosphate + H+ + NADPH.,glutamate-5-semialdehyde dehydrogenase (NADP+) activity,molecular_function
60005,GO:0004351,Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.,glutamate decarboxylase activity,molecular_function
60006,GO:0004352,Catalysis of the reaction: L-glutamate + NAD+ + H2O = 2-oxoglutarate + NH4+ + NADH + H+.,L-glutamate dehydrogenase (NAD+) activity,molecular_function
60007,GO:0004353,Catalysis of the reaction: L-glutamate + NAD(P)+ + H2O = 2-oxoglutarate + NH4+ + NAD(P)H + H+.,L-glutamate dehydrogenase [NAD(P)+] activity,molecular_function
60008,GO:0004354,Catalysis of the reaction: L-glutamate + NADP+ + H2O = 2-oxoglutarate + NH4+ + NADPH + H+.,L-glutamate dehydrogenase (NADP+) activity,molecular_function
60009,GO:0004355,"Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH4+ = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH4+ + 2-oxoglutarate + NADPH + H+.",glutamate synthase (NADPH) activity,molecular_function
60010,GO:0004356,Catalysis of the reaction: ATP + L-glutamate + NH4+ = ADP + H+ + L-glutamine + phosphate.,glutamine synthetase activity,molecular_function
60011,GO:0004357,Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H+ + phosphate.,glutamate-cysteine ligase activity,molecular_function
60012,GO:0004358,Catalysis of the reaction: N2-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.,"L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor",molecular_function
60013,GO:0004359,Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH4+.,glutaminase activity,molecular_function
60014,GO:0004360,Catalysis of the reaction: D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.,L-glutamine:D-fructose-6-phosphate transaminase (isomerizing) activity,molecular_function
60015,GO:0004361,Catalysis of the reaction: glutaryl-CoA + 2 H+ + oxidized [electron-transfer flavoprotein] = (2E)-butenoyl-CoA + CO2 + reduced [electron-transfer flavoprotein].,glutaryl-CoA dehydrogenase activity,molecular_function
60016,GO:0004362,Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.,glutathione-disulfide reductase (NADPH) activity,molecular_function
60017,GO:0004363,Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate.,glutathione synthase activity,molecular_function
60018,GO:0004364,Catalysis of the reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H+.,glutathione transferase activity,molecular_function
60019,GO:0004365,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.,glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity,molecular_function
60020,GO:0004366,Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA.,glycerol-3-phosphate O-acyltransferase activity,molecular_function
60021,GO:0004368,Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.,glycerol-3-phosphate dehydrogenase (quinone) activity,molecular_function
60022,GO:0004369,Catalysis of the reaction: sn-glycerol 3-phosphate + O2 = glycerone phosphate + H2O2.,glycerol-3-phosphate oxidase activity,molecular_function
60023,GO:0004370,Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H+.,glycerol kinase activity,molecular_function
60024,GO:0004371,Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H+.,glycerone kinase activity,molecular_function
60025,GO:0004372,"Catalysis of the reaction: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine.",glycine hydroxymethyltransferase activity,molecular_function
60026,GO:0004373,Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + H+ + UDP.,"alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity",molecular_function
60027,GO:0004375,Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H+ = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.,glycine dehydrogenase (decarboxylating) activity,molecular_function
60028,GO:0004376,Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to GlcN-acyl-PI bearing 0-3 mannoses during formation of the GPI precursor.,GPI mannosyltransferase activity,molecular_function
60029,GO:0004377,"Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H+.","GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity",molecular_function
60030,GO:0004378,"Catalysis of the reaction: a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H+.","GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity",molecular_function
60031,GO:0004379,Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.,glycylpeptide N-tetradecanoyltransferase activity,molecular_function
60032,GO:0004380,"Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.",glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity,molecular_function
60033,GO:0004381,"Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.",fucosylgalactoside 3-alpha-galactosyltransferase activity,molecular_function
60034,GO:0004382,Catalysis of the reaction: GDP + H2O = GMP + phosphate.,GDP phosphatase activity,molecular_function
60035,GO:0004383,"Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.",guanylate cyclase activity,molecular_function
60036,GO:0004385,Catalysis of the reaction: ATP + GMP = ADP + GDP.,GMP kinase activity,molecular_function
60037,GO:0004386,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.",helicase activity,molecular_function
60038,GO:0004392,Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].,heme oxygenase (decyclizing) activity,molecular_function
60039,GO:0004394,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.",heparan sulfate 2-sulfotransferase activity,molecular_function
60040,GO:0004396,Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.,hexokinase activity,molecular_function
60041,GO:0004397,Catalysis of the reaction: L-histidine = trans-urocanate + NH4+.,histidine ammonia-lyase activity,molecular_function
60042,GO:0004398,Catalysis of the reaction: L-histidine = histamine + CO2.,histidine decarboxylase activity,molecular_function
60043,GO:0004399,Catalysis of the reaction: H2O + L-histidinol + 2 NAD+ = 3 H+ + L-histidine + 2 NADH.,histidinol dehydrogenase activity,molecular_function
60044,GO:0004400,Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.,L-histidinol-phosphate:2-oxoglutarate transaminase activity,molecular_function
60045,GO:0004401,Catalysis of the reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate.,histidinol-phosphatase activity,molecular_function
60046,GO:0004402,Catalysis of the reaction: L-lysyl-[histone] + acetyl-CoA = N6-acetyl-L-lysyl-[histone] + CoA + H+.,histone acetyltransferase activity,molecular_function
60047,GO:0004407,Removal of an acetyl group from a lysine residue in a histone.,histone deacetylase activity,molecular_function
60048,GO:0004408,Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.,holocytochrome-c synthase activity,molecular_function
60049,GO:0004409,Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H2O.,homoaconitate hydratase activity,molecular_function
60050,GO:0004410,Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H2O = CoA + H+ + homocitrate.,homocitrate synthase activity,molecular_function
60051,GO:0004411,Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate + H+.,"homogentisate 1,2-dioxygenase activity",molecular_function
60052,GO:0004412,Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.,homoserine dehydrogenase activity,molecular_function
60053,GO:0004413,Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H+.,homoserine kinase activity,molecular_function
60054,GO:0004414,Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.,homoserine O-acetyltransferase activity,molecular_function
60055,GO:0004415,Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.,hyalurononglucosaminidase activity,molecular_function
60056,GO:0004416,Catalysis of the reaction: an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H+.,hydroxyacylglutathione hydrolase activity,molecular_function
60057,GO:0004417,Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H+.,hydroxyethylthiazole kinase activity,molecular_function
60058,GO:0004418,Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4.,hydroxymethylbilane synthase activity,molecular_function
60059,GO:0004419,Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.,hydroxymethylglutaryl-CoA lyase activity,molecular_function
60060,GO:0004420,Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.,hydroxymethylglutaryl-CoA reductase (NADPH) activity,molecular_function
60061,GO:0004421,Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+.,hydroxymethylglutaryl-CoA synthase activity,molecular_function
60062,GO:0004422,Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.,hypoxanthine phosphoribosyltransferase activity,molecular_function
60063,GO:0004423,"Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.",iduronate-2-sulfatase activity,molecular_function
60064,GO:0004424,Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O.,imidazoleglycerol-phosphate dehydratase activity,molecular_function
60065,GO:0004425,Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.,indole-3-glycerol-phosphate synthase activity,molecular_function
60066,GO:0004427,Catalysis of the reaction: diphosphate + H2O = H+ + 2 phosphate.,inorganic diphosphate phosphatase activity,molecular_function
60067,GO:0004430,Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + H+.,1-phosphatidylinositol 4-kinase activity,molecular_function
60068,GO:0004435,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H+.","phosphatidylinositol-4,5-bisphosphate phospholipase C activity",molecular_function
60069,GO:0004436,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol.",phosphatidylinositol diacylglycerol-lyase activity,molecular_function
60070,GO:0004438,Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.,phosphatidylinositol-3-phosphate phosphatase activity,molecular_function
60071,GO:0004439,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.","phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",molecular_function
60072,GO:0004441,"Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.","inositol-1,4-bisphosphate 1-phosphatase activity",molecular_function
60073,GO:0004445,"Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.",inositol-polyphosphate 5-phosphatase activity,molecular_function
60074,GO:0004446,Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate + phosphate.,inositol hexakisphosphate phosphatase activity,molecular_function
60075,GO:0004447,"Catalysis of the reactions: (1) 2 iodide + H2O2 + 2 H+ = diiodine + 2 H2O; (2) [thyroglobulin]-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O; (3) [thyroglobulin]-3-iodo-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O; (4) 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-L-thyroxine + [thyroglobulin]-dehydroalanine + 2 H2O; (5) [thyroglobulin]-3-iodo-L-tyrosine + [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyrog...",iodide peroxidase activity,molecular_function
60076,GO:0004448,Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.,isocitrate dehydrogenase [NAD(P)+] activity,molecular_function
60077,GO:0004449,Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.,isocitrate dehydrogenase (NAD+) activity,molecular_function
60078,GO:0004450,Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.,isocitrate dehydrogenase (NADP+) activity,molecular_function
60079,GO:0004451,Catalysis of the reaction: isocitrate = glyoxylate + succinate.,isocitrate lyase activity,molecular_function
60080,GO:0004452,Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.,isopentenyl-diphosphate delta-isomerase activity,molecular_function
60081,GO:0004453,"Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.",juvenile-hormone esterase activity,molecular_function
60082,GO:0004454,Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.,ketohexokinase activity,molecular_function
60083,GO:0004455,"Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.",ketol-acid reductoisomerase activity,molecular_function
60084,GO:0004456,Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.,phosphogluconate dehydratase activity,molecular_function
60085,GO:0004457,Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.,lactate dehydrogenase activity,molecular_function
60086,GO:0004458,Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.,D-lactate dehydrogenase (cytochrome) activity,molecular_function
60087,GO:0004459,Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.,L-lactate dehydrogenase (NAD+) activity,molecular_function
60088,GO:0004460,Catalysis of the reaction: (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.,L-lactate dehydrogenase (cytochrome) activity,molecular_function
60089,GO:0004461,Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.,lactose synthase activity,molecular_function
60090,GO:0004462,Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.,lactoylglutathione lyase activity,molecular_function
60091,GO:0004463,Catalysis of the reaction: H2O + leukotriene A(4) = leukotriene B(4).,leukotriene-A4 hydrolase activity,molecular_function
60092,GO:0004464,Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).,leukotriene-C4 synthase activity,molecular_function
60093,GO:0004465,"Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein. May also hydrolyze diacylglycerol and phospholipids present in lipoproteins.",lipoprotein lipase activity,molecular_function
60094,GO:0004466,"Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty acyl-CoA dehydrogenase activity,molecular_function
60095,GO:0004467,Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid-CoA ligase activity,molecular_function
60096,GO:0004468,Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.,"L-lysine N6-acetyltransferase activity, acting on acetyl phosphate as donor",molecular_function
60097,GO:0004470,Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.,malic enzyme activity,molecular_function
60098,GO:0004471,Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH.,malate dehydrogenase (decarboxylating) (NAD+) activity,molecular_function
60099,GO:0004473,Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH.,malate dehydrogenase (decarboxylating) (NADP+) activity,molecular_function
60100,GO:0004474,Catalysis of the reaction: acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H+.,malate synthase activity,molecular_function
60101,GO:0004475,Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.,mannose-1-phosphate guanylyltransferase (GTP) activity,molecular_function
60102,GO:0004476,Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.,mannose-6-phosphate isomerase activity,molecular_function
60103,GO:0004477,"Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.",methenyltetrahydrofolate cyclohydrolase activity,molecular_function
60104,GO:0004478,Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.,methionine adenosyltransferase activity,molecular_function
60105,GO:0004479,Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.,methionyl-tRNA formyltransferase activity,molecular_function
60106,GO:0004481,Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid.,methylene-fatty-acyl-phospholipid synthase activity,molecular_function
60107,GO:0004482,Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.,mRNA 5'-cap (guanine-N7-)-methyltransferase activity,molecular_function
60108,GO:0004483,Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the first transcribed nucleotide of mRNAs and snRNAs.,methyltransferase cap1 activity,molecular_function
60109,GO:0004484,Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.,mRNA guanylyltransferase activity,molecular_function
60110,GO:0004485,Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H+ + phosphate.,methylcrotonoyl-CoA carboxylase activity,molecular_function
60111,GO:0004487,"Catalysis of the reaction: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD+ = (6R)-5,10-methenyltetrahydrofolate + NADH.",methylenetetrahydrofolate dehydrogenase (NAD+) activity,molecular_function
60112,GO:0004488,"Catalysis of the reaction: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP+ = (6R)-5,10-methenyltetrahydrofolate + NADPH.",methylenetetrahydrofolate dehydrogenase (NADP+) activity,molecular_function
60113,GO:0004489,"Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(P)+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(P)H + H+.",methylenetetrahydrofolate reductase [NAD(P)H] activity,molecular_function
60114,GO:0004490,Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H2O.,methylglutaconyl-CoA hydratase activity,molecular_function
60115,GO:0004491,Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + hydrogencarbonate + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product.,"methylmalonate-semialdehyde dehydrogenase (acylating, NAD+) activity",molecular_function
60116,GO:0004492,Catalysis of the reaction: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA or (2S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2.,methyl/ethyl malonyl-CoA decarboxylase activity,molecular_function
60117,GO:0004493,Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.,methylmalonyl-CoA epimerase activity,molecular_function
60118,GO:0004494,Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.,methylmalonyl-CoA mutase activity,molecular_function
60119,GO:0004496,Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H+.,mevalonate kinase activity,molecular_function
60120,GO:0004497,Catalysis of the incorporation of one atom of molecular oxygen (O2) into the substrate and the reduction of the other atom of O2 to water.,monooxygenase activity,molecular_function
60121,GO:0004498,Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+.,calcidiol 1-monooxygenase activity,molecular_function
60122,GO:0004499,"Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.","N,N-dimethylaniline monooxygenase activity",molecular_function
60123,GO:0004500,Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O.,dopamine beta-monooxygenase activity,molecular_function
60124,GO:0004501,Catalysis of the reaction: AH(2) + ecdysone + O2 = 20-hydroxyecdysone + A + H2O.,ecdysone 20-monooxygenase activity,molecular_function
60125,GO:0004502,Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+.,kynurenine 3-monooxygenase activity,molecular_function
60126,GO:0004503,Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.,tyrosinase activity,molecular_function
60127,GO:0004504,Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.,peptidylglycine monooxygenase activity,molecular_function
60128,GO:0004505,Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.,phenylalanine 4-monooxygenase activity,molecular_function
60129,GO:0004506,"Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+.",squalene monooxygenase activity,molecular_function
60130,GO:0004507,Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.,steroid 11-beta-monooxygenase activity,molecular_function
60131,GO:0004508,Catalysis of the reaction: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] = a 17alpha-hydroxy-C21-steroid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,steroid 17-alpha-monooxygenase activity,molecular_function
60132,GO:0004509,Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O.,steroid 21-monooxygenase activity,molecular_function
60133,GO:0004510,Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.,tryptophan 5-monooxygenase activity,molecular_function
60134,GO:0004511,"Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.",tyrosine 3-monooxygenase activity,molecular_function
60135,GO:0004512,"Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.",inositol-3-phosphate synthase activity,molecular_function
60136,GO:0004514,Catalysis of the reaction: CO2 + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H+ + quinolinate.,nicotinate-nucleotide diphosphorylase (carboxylating) activity,molecular_function
60137,GO:0004515,Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.,nicotinate-nucleotide adenylyltransferase activity,molecular_function
60138,GO:0004516,Catalysis of the reaction: nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.,nicotinate phosphoribosyltransferase activity,molecular_function
60139,GO:0004517,Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.,nitric-oxide synthase activity,molecular_function
60140,GO:0004518,Catalysis of the cleavage of ester linkages within nucleic acids.,nuclease activity,molecular_function
60141,GO:0004519,Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.,endonuclease activity,molecular_function
60142,GO:0004520,Catalysis of the cleavage of ester linkages within deoxyribonucleic acid by creating internal breaks.,DNA endonuclease activity,molecular_function
60143,GO:0004521,Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks.,RNA endonuclease activity,molecular_function
60144,GO:0004522,"Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.",ribonuclease A activity,molecular_function
60145,GO:0004523,Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.,RNA-DNA hybrid ribonuclease activity,molecular_function
60146,GO:0004525,"Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.",ribonuclease III activity,molecular_function
60147,GO:0004526,"Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.",ribonuclease P activity,molecular_function
60148,GO:0004527,Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.,exonuclease activity,molecular_function
60149,GO:0004528,Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.,phosphodiesterase I activity,molecular_function
60150,GO:0004529,Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.,DNA exonuclease activity,molecular_function
60151,GO:0004530,Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.,deoxyribonuclease I activity,molecular_function
60152,GO:0004531,Catalysis of the endonucleolytic cleavage of DNA to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.,deoxyribonuclease II activity,molecular_function
60153,GO:0004532,Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.,RNA exonuclease activity,molecular_function
60154,GO:0004533,Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.,exoribonuclease H activity,molecular_function
60155,GO:0004534,Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.,5'-3' RNA exonuclease activity,molecular_function
60156,GO:0004535,Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.,poly(A)-specific ribonuclease activity,molecular_function
60157,GO:0004536,Catalysis of the cleavage of ester linkages within deoxyribonucleic acid.,DNA nuclease activity,molecular_function
60158,GO:0004540,Catalysis of the cleavage of phosphodiester bonds in chains of RNA.,RNA nuclease activity,molecular_function
60159,GO:0004549,Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.,tRNA-specific ribonuclease activity,molecular_function
60160,GO:0004550,Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.,nucleoside diphosphate kinase activity,molecular_function
60161,GO:0004551,Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.,dinucleotide phosphatase activity,molecular_function
60162,GO:0004552,Catalysis of the reaction: 1-octanol + NAD+ = 1-octanal + H+ + NADH.,octanol dehydrogenase (NAD+) activity,molecular_function
60163,GO:0004553,Catalysis of the hydrolysis of any O-glycosyl bond.,"hydrolase activity, hydrolyzing O-glycosyl compounds",molecular_function
60164,GO:0004555,"Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.","alpha,alpha-trehalase activity",molecular_function
60165,GO:0004556,Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.,alpha-amylase activity,molecular_function
60166,GO:0004557,"Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.",alpha-galactosidase activity,molecular_function
60167,GO:0004558,"Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.","alpha-1,4-glucosidase activity",molecular_function
60168,GO:0004559,"Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.",alpha-mannosidase activity,molecular_function
60169,GO:0004560,Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.,alpha-L-fucosidase activity,molecular_function
60170,GO:0004561,Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.,alpha-N-acetylglucosaminidase activity,molecular_function
60171,GO:0004563,Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.,beta-N-acetylhexosaminidase activity,molecular_function
60172,GO:0004564,Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.,beta-fructofuranosidase activity,molecular_function
60173,GO:0004565,"Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.",beta-galactosidase activity,molecular_function
60174,GO:0004566,Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.,beta-glucuronidase activity,molecular_function
60175,GO:0004567,"Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.",beta-mannosidase activity,molecular_function
60176,GO:0004568,Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.,chitinase activity,molecular_function
60177,GO:0004569,"Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.","glycoprotein endo-alpha-1,2-mannosidase activity",molecular_function
60178,GO:0004571,Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",molecular_function
60179,GO:0004572,Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).,"mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity",molecular_function
60180,GO:0004573,Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).,Glc3Man9GlcNAc2 oligosaccharide glucosidase activity,molecular_function
60181,GO:0004574,"Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.","oligo-1,6-glucosidase activity",molecular_function
60182,GO:0004575,Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.,sucrose alpha-glucosidase activity,molecular_function
60183,GO:0004576,"Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.",oligosaccharyl transferase activity,molecular_function
60184,GO:0004577,"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.",N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity,molecular_function
60185,GO:0004578,"Catalysis of the reaction: an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H+.",chitobiosyldiphosphodolichol beta-mannosyltransferase activity,molecular_function
60186,GO:0004579,Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.,dolichyl-diphosphooligosaccharide-protein glycotransferase activity,molecular_function
60187,GO:0004581,Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.,dolichyl-phosphate beta-glucosyltransferase activity,molecular_function
60188,GO:0004582,Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.,dolichyl-phosphate beta-D-mannosyltransferase activity,molecular_function
60189,GO:0004583,Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.,dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity,molecular_function
60190,GO:0004585,Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.,ornithine carbamoyltransferase activity,molecular_function
60191,GO:0004586,Catalysis of the reaction: L-ornithine + H+ = CO2 + putrescine.,ornithine decarboxylase activity,molecular_function
60192,GO:0004587,Catalysis of the reaction: a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid.,L-ornithine transaminase activity,molecular_function
60193,GO:0004588,Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.,orotate phosphoribosyltransferase activity,molecular_function
60194,GO:0004589,Catalysis of the reaction: (S)-dihydroorotate + NAD+ = H+ + NADH + orotate.,dihydroorotate dehydrogenase (NAD+) activity,molecular_function
60195,GO:0004590,Catalysis of the reaction: H+ + orotidine 5'-phosphate = CO2 + UMP.,orotidine-5'-phosphate decarboxylase activity,molecular_function
60196,GO:0004591,Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H+ = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2.,oxoglutarate dehydrogenase (succinyl-transferring) activity,molecular_function
60197,GO:0004592,Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.,pantoate-beta-alanine ligase activity,molecular_function
60198,GO:0004593,Catalysis of the reaction: (R)-pantothenate + H2O = (R)-pantoate + beta-alanine.,pantothenase activity,molecular_function
60199,GO:0004594,Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.,pantothenate kinase activity,molecular_function
60200,GO:0004595,Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.,pantetheine-phosphate adenylyltransferase activity,molecular_function
60201,GO:0004596,Catalysis of the reaction: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-alpha-aminoacyl-[protein].,protein-N-terminal amino-acid acetyltransferase activity,molecular_function
60202,GO:0004598,Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.,peptidylamidoglycolate lyase activity,molecular_function
60203,GO:0004601,Catalysis of the reaction: a reduced substrate + ROOH = an oxidized substrate + ROH + H2O.,peroxidase activity,molecular_function
60204,GO:0004602,Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.,glutathione peroxidase activity,molecular_function
60205,GO:0004603,Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.,phenylethanolamine N-methyltransferase activity,molecular_function
60206,GO:0004604,"Catalysis of the reaction: adenosine 3',5'-diphosphate + H+ + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.",phosphoadenylyl-sulfate reductase (thioredoxin) activity,molecular_function
60207,GO:0004605,Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.,phosphatidate cytidylyltransferase activity,molecular_function
60208,GO:0004607,Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.,phosphatidylcholine-sterol O-acyltransferase activity,molecular_function
60209,GO:0004608,Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.,phosphatidylethanolamine N-methyltransferase activity,molecular_function
60210,GO:0004609,Catalysis of the reaction: H+ + phosphatidyl-L-serine = CO2 + phosphatidylethanolamine.,phosphatidylserine decarboxylase activity,molecular_function
60211,GO:0004610,Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.,phosphoacetylglucosamine mutase activity,molecular_function
60212,GO:0004611,Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.,phosphoenolpyruvate carboxykinase activity,molecular_function
60213,GO:0004612,Catalysis of the reaction: ATP + oxaloacetate = ADP + CO2 + H+ + phosphoenolpyruvate.,phosphoenolpyruvate carboxykinase (ATP) activity,molecular_function
60214,GO:0004613,Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.,phosphoenolpyruvate carboxykinase (GTP) activity,molecular_function
60215,GO:0004614,Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.,phosphoglucomutase activity,molecular_function
60216,GO:0004615,Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.,phosphomannomutase activity,molecular_function
60217,GO:0004616,Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.,phosphogluconate dehydrogenase (decarboxylating) activity,molecular_function
60218,GO:0004617,Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.,phosphoglycerate dehydrogenase activity,molecular_function
60219,GO:0004618,Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H+.,phosphoglycerate kinase activity,molecular_function
60220,GO:0004619,Catalysis of the reaction: (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.,phosphoglycerate mutase activity,molecular_function
60221,GO:0004620,Catalysis of the hydrolysis of a glycerophospholipid.,glycerophospholipase activity,molecular_function
60222,GO:0004621,"Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol, by cleavage of the second phosphodiester bond between the phosphate and phospholipid.",GPI anchor phospholipase D activity,molecular_function
60223,GO:0004622,Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine.,phosphatidylcholine lysophospholipase A1 activity,molecular_function
60224,GO:0004623,"A glycerophospholipase activity that cleaves the fatty acid attached to the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.",A2-type glycerophospholipase activity,molecular_function
60225,GO:0004629,"A glycerophospholipase activity that cleaves the first phosphodiester bond between the phosphate and glycerol, producing a mono- or a diacylglycerol, depending on whether the substrate is a lysoglycerophospholipid or a glycerophospholipid.",C-type glycerophospholipase activity,molecular_function
60226,GO:0004630,"A glycerophospholipase activity that cleaves the second phosphodiester bond between the phosphate and phospholipid, releasing a phosphatidic acid.",D-type glycerophospholipase activity,molecular_function
60227,GO:0004631,Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H+.,phosphomevalonate kinase activity,molecular_function
60228,GO:0004632,Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.,phosphopantothenate--cysteine ligase activity,molecular_function
60229,GO:0004633,Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H+ = CO2 + pantetheine 4'-phosphate.,phosphopantothenoylcysteine decarboxylase activity,molecular_function
60230,GO:0004634,Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.,phosphopyruvate hydratase activity,molecular_function
60231,GO:0004635,Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H2O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.,phosphoribosyl-AMP cyclohydrolase activity,molecular_function
60232,GO:0004636,Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H2O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H+.,phosphoribosyl-ATP diphosphatase activity,molecular_function
60233,GO:0004637,Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.,phosphoribosylamine-glycine ligase activity,molecular_function
60234,GO:0004638,Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2.,phosphoribosylaminoimidazole carboxylase activity,molecular_function
60235,GO:0004639,Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H+ + phosphate.,phosphoribosylaminoimidazolesuccinocarboxamide synthase activity,molecular_function
60236,GO:0004640,Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.,phosphoribosylanthranilate isomerase activity,molecular_function
60237,GO:0004641,Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H+ + phosphate.,phosphoribosylformylglycinamidine cyclo-ligase activity,molecular_function
60238,GO:0004642,Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H+ + phosphate.,phosphoribosylformylglycinamidine synthase activity,molecular_function
60239,GO:0004643,Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.,phosphoribosylaminoimidazolecarboxamide formyltransferase activity,molecular_function
60240,GO:0004644,Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.,phosphoribosylglycinamide formyltransferase activity,molecular_function
60241,GO:0004645,"Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.","1,4-alpha-oligoglucan phosphorylase activity",molecular_function
60242,GO:0004648,Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.,O-phospho-L-serine:2-oxoglutarate transaminase activity,molecular_function
60243,GO:0004649,Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.,poly(ADP-ribose) glycohydrolase activity,molecular_function
60244,GO:0004650,Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.,polygalacturonase activity,molecular_function
60245,GO:0004651,Catalysis of the reaction: a 5'-phosphopolynucleotide + H2O = a polynucleotide + phosphate.,polynucleotide 5'-phosphatase activity,molecular_function
60246,GO:0004653,Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.,polypeptide N-acetylgalactosaminyltransferase activity,molecular_function
60247,GO:0004654,Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.,polyribonucleotide nucleotidyltransferase activity,molecular_function
60248,GO:0004655,Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.,porphobilinogen synthase activity,molecular_function
60249,GO:0004656,Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.,procollagen-proline 4-dioxygenase activity,molecular_function
60250,GO:0004657,Catalysis of the reaction: L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H+.,proline dehydrogenase activity,molecular_function
60251,GO:0004658,Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.,propionyl-CoA carboxylase activity,molecular_function
60252,GO:0004659,Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).,prenyltransferase activity,molecular_function
60253,GO:0004660,"Catalysis of the reaction: L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.",protein farnesyltransferase activity,molecular_function
60254,GO:0004661,Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.,protein geranylgeranyltransferase activity,molecular_function
60255,GO:0004662,"Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins...",CAAX-protein geranylgeranyltransferase activity,molecular_function
60256,GO:0004663,"Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.",Rab geranylgeranyltransferase activity,molecular_function
60257,GO:0004664,Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.,prephenate dehydratase activity,molecular_function
60258,GO:0004665,Catalysis of the reaction: NADP+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADPH.,prephenate dehydrogenase (NADP+) activity,molecular_function
60259,GO:0004666,"Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2.",prostaglandin-endoperoxide synthase activity,molecular_function
60260,GO:0004667,Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).,prostaglandin-D synthase activity,molecular_function
60261,GO:0004668,"Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent.",protein-arginine deiminase activity,molecular_function
60262,GO:0004671,Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.,protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity,molecular_function
60263,GO:0004672,"Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.",protein kinase activity,molecular_function
60264,GO:0004673,Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.,protein histidine kinase activity,molecular_function
60265,GO:0004674,"Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",protein serine/threonine kinase activity,molecular_function
60266,GO:0004675,"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",transmembrane receptor protein serine/threonine kinase activity,molecular_function
60267,GO:0004676,Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,3-phosphoinositide-dependent protein kinase activity,molecular_function
60268,GO:0004677,DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,DNA-dependent protein kinase activity,molecular_function
60269,GO:0004679,Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.,AMP-activated protein kinase activity,molecular_function
60270,GO:0004683,Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. This activity require the presence of calcium-bound calmodulin.,calcium/calmodulin-dependent protein kinase activity,molecular_function
60271,GO:0004686,Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.,elongation factor-2 kinase activity,molecular_function
60272,GO:0004687,Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.,myosin light chain kinase activity,molecular_function
60273,GO:0004689,Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.,phosphorylase kinase activity,molecular_function
60274,GO:0004690,cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,cyclic nucleotide-dependent protein kinase activity,molecular_function
60275,GO:0004691,cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,cAMP-dependent protein kinase activity,molecular_function
60276,GO:0004692,cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,cGMP-dependent protein kinase activity,molecular_function
60277,GO:0004693,"Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",cyclin-dependent protein serine/threonine kinase activity,molecular_function
60278,GO:0004694,Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.,eukaryotic translation initiation factor 2alpha kinase activity,molecular_function
60279,GO:0004697,Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.,diacylglycerol-dependent serine/threonine kinase activity,molecular_function
60280,GO:0004698,Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction is activated in the presence of diacylglycerol and calcium.,"calcium,diacylglycerol-dependent serine/threonine kinase activity",molecular_function
60281,GO:0004699,Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction is activated by diacylglycerol but not by calcium.,"diacylglycerol-dependent, calcium-independent serine/threonine kinase activity",molecular_function
60282,GO:0004703,Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.,G protein-coupled receptor kinase activity,molecular_function
60283,GO:0004705,"Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.",JUN kinase activity,molecular_function
60284,GO:0004706,Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).,JUN kinase kinase kinase activity,molecular_function
60285,GO:0004707,"Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgroun...",MAP kinase activity,molecular_function
60286,GO:0004708,Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate.,MAP kinase kinase activity,molecular_function
60287,GO:0004709,Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.,MAP kinase kinase kinase activity,molecular_function
60288,GO:0004711,Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.,ribosomal protein S6 kinase activity,molecular_function
60289,GO:0004712,Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.,protein serine/threonine/tyrosine kinase activity,molecular_function
60290,GO:0004713,Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.,protein tyrosine kinase activity,molecular_function
60291,GO:0004714,Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.,transmembrane receptor protein tyrosine kinase activity,molecular_function
60292,GO:0004715,Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.,non-membrane spanning protein tyrosine kinase activity,molecular_function
60293,GO:0004719,Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.,protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,molecular_function
60294,GO:0004720,Catalysis of the reaction: L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4+.,protein-lysine 6-oxidase activity,molecular_function
60295,GO:0004721,"Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.",phosphoprotein phosphatase activity,molecular_function
60296,GO:0004722,"Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.",protein serine/threonine phosphatase activity,molecular_function
60297,GO:0004723,Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.,calcium-dependent protein serine/threonine phosphatase activity,molecular_function
60298,GO:0004725,Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.,protein tyrosine phosphatase activity,molecular_function
60299,GO:0004726,Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.,non-membrane spanning protein tyrosine phosphatase activity,molecular_function
60300,GO:0004729,Catalysis of the reaction: 3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX.,"protoporphyrinogen oxidase activity, oxygen as acceptor",molecular_function
60301,GO:0004730,Catalysis of the reaction: D-ribose 5-phosphate + uracil = H2O + pseudouridine 5'-phosphate.,pseudouridylate synthase activity,molecular_function
60302,GO:0004731,Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.,purine-nucleoside phosphorylase activity,molecular_function
60303,GO:0004732,Catalysis of the reaction:  pyridoxal + H2O + O2 = 4-pyridoxate + H+ + H2O2.,pyridoxal oxidase activity,molecular_function
60304,GO:0004733,Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH4+ + H2O2. This activity can also oxidize pyridoxine 5'-phosphate to pyridoxal 5'-phosphate + H2O2.,pyridoxamine phosphate oxidase activity,molecular_function
60305,GO:0004734,Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.,pyrimidodiazepine synthase activity,molecular_function
60306,GO:0004735,Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.,pyrroline-5-carboxylate reductase activity,molecular_function
60307,GO:0004736,Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H+ + oxaloacetate + phosphate.,pyruvate carboxylase activity,molecular_function
60308,GO:0004737,Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.,pyruvate decarboxylase activity,molecular_function
60309,GO:0004739,Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H+ = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.,pyruvate dehydrogenase (acetyl-transferring) activity,molecular_function
60310,GO:0004740,Catalysis of the reaction: ATP + L-seryl-[pyruvate dehydrogenase E1 alpha subunit] = ADP + H+ + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit].,pyruvate dehydrogenase (acetyl-transferring) kinase activity,molecular_function
60311,GO:0004741,Catalysis of the reaction: O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.,[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity,molecular_function
60312,GO:0004742,Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA.,dihydrolipoyllysine-residue acetyltransferase activity,molecular_function
60313,GO:0004743,Catalysis of the reaction: ADP + H+ + phosphoenolpyruvate = ATP + pyruvate.,pyruvate kinase activity,molecular_function
60314,GO:0004745,"Catalysis of the reaction: all-trans-retinol--[retinol-binding protein] + NAD+ = all-trans-retinal--[retinol-binding protein] + H+ + NADH. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein (CRBP1), but has higher affinity for the bound form.",all-trans-retinol dehydrogenase (NAD+) activity,molecular_function
60315,GO:0004746,"Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ = 5-amino-6-(D-ribitylamino)uracil + riboflavin.",riboflavin synthase activity,molecular_function
60316,GO:0004747,Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.,ribokinase activity,molecular_function
60317,GO:0004748,Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.,"ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",molecular_function
60318,GO:0004749,Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H+.,ribose phosphate diphosphokinase activity,molecular_function
60319,GO:0004750,Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate.,D-ribulose-phosphate 3-epimerase activity,molecular_function
60320,GO:0004751,Catalysis of the reaction: aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate.,ribose-5-phosphate isomerase activity,molecular_function
60321,GO:0004753,"Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.",saccharopine dehydrogenase activity,molecular_function
60322,GO:0004754,Catalysis of the reaction: L-saccharopine + H2O + NAD+ = 2-oxoglutarate + L-lysine + H+ + NADH.,"saccharopine dehydrogenase (NAD+, L-lysine-forming) activity",molecular_function
60323,GO:0004755,Catalysis of the reaction: L-saccharopine + H2O + NADP+ = L-allysine + L-glutamate + H+ + NADPH.,"saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity",molecular_function
60324,GO:0004756,Catalysis of the reaction: ATP + H2O + hydrogen selenide = AMP + 3 H+ + phosphate + selenophosphorate.,"selenide, water dikinase activity",molecular_function
60325,GO:0004757,"Catalysis of the reactions: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+ and (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP+ = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H+ + 2 NADPH.",sepiapterin reductase (NADP+) activity,molecular_function
60326,GO:0004758,Catalysis of the reaction: L-serine + H+ + palmitoyl-CoA = 3-dehydrosphinganine + CO2 + CoA.,serine C-palmitoyltransferase activity,molecular_function
60327,GO:0004760,Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.,L-serine:pyruvate transaminase activity,molecular_function
60328,GO:0004764,Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.,shikimate 3-dehydrogenase (NADP+) activity,molecular_function
60329,GO:0004765,Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H+.,shikimate kinase activity,molecular_function
60330,GO:0004766,Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.,spermidine synthase activity,molecular_function
60331,GO:0004767,Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+.,sphingomyelin phosphodiesterase activity,molecular_function
60332,GO:0004768,Catalysis of the reaction: 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.,stearoyl-CoA 9-desaturase activity,molecular_function
60333,GO:0004769,Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.,steroid Delta-isomerase activity,molecular_function
60334,GO:0004771,Catalysis of the reaction: a sterol ester + H2O = a fatty acid + a sterol + H+.,sterol ester esterase activity,molecular_function
60335,GO:0004772,Catalysis of the reaction: a long-chain fatty acyl-CoA + a sterol = a sterol ester + CoA.,sterol O-acyltransferase activity,molecular_function
60336,GO:0004773,Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.,steryl-sulfatase activity,molecular_function
60337,GO:0004774,Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.,succinate-CoA ligase activity,molecular_function
60338,GO:0004775,Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.,succinate-CoA ligase (ADP-forming) activity,molecular_function
60339,GO:0004776,Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.,succinate-CoA ligase (GDP-forming) activity,molecular_function
60340,GO:0004777,Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.,succinate-semialdehyde dehydrogenase (NAD+) activity,molecular_function
60341,GO:0004778,Catalysis of the reaction: H2O + succinyl-CoA = CoA + H+ + succinate.,succinyl-CoA hydrolase activity,molecular_function
60342,GO:0004779,"Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate.",sulfate adenylyltransferase activity,molecular_function
60343,GO:0004780,Catalysis of the reaction: ADP + H+ + sulfate = 5'-adenylyl sulfate + phosphate.,sulfate adenylyltransferase (ADP) activity,molecular_function
60344,GO:0004781,Catalysis of the reaction: sulfate + ATP + H+ = adenosine 5'-phosphosulfate + diphosphate.,sulfate adenylyltransferase (ATP) activity,molecular_function
60345,GO:0004782,Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.,sulfinoalanine decarboxylase activity,molecular_function
60346,GO:0004783,Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.,sulfite reductase (NADPH) activity,molecular_function
60347,GO:0004784,Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2.,superoxide dismutase activity,molecular_function
60348,GO:0004787,Catalysis of the reaction: thiamine diphosphate + H2O = thiamine monophosphate + phosphate.,thiamine diphosphate phosphatase activity,molecular_function
60349,GO:0004788,Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.,thiamine diphosphokinase activity,molecular_function
60350,GO:0004789,Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H+ = diphosphate + thiamine phosphate.,thiamine-phosphate diphosphorylase activity,molecular_function
60351,GO:0004790,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.,thioether S-methyltransferase activity,molecular_function
60352,GO:0004791,Catalysis of the reaction: thioredoxin-dithiol + NADP+ = thioredoxin-disulfide + H+ + NADPH.,thioredoxin-disulfide reductase (NADPH) activity,molecular_function
60353,GO:0004792,Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+.,thiosulfate-cyanide sulfurtransferase activity,molecular_function
60354,GO:0004793,Catalysis of the reaction: L-threonine = glycine + acetaldehyde.,threonine aldolase activity,molecular_function
60355,GO:0004794,Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH4.,threonine deaminase activity,molecular_function
60356,GO:0004795,Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.,threonine synthase activity,molecular_function
60357,GO:0004796,Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).,thromboxane-A synthase activity,molecular_function
60358,GO:0004797,Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.,thymidine kinase activity,molecular_function
60359,GO:0004798,Catalysis of the reaction: dTMP + ATP = dTDP + ADP.,dTMP kinase activity,molecular_function
60360,GO:0004799,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.",thymidylate synthase activity,molecular_function
60361,GO:0004800,"Catalysis of the reaction: 3,3',5-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + acceptor-H2.",thyroxine 5'-deiodinase activity,molecular_function
60362,GO:0004801,Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.,transaldolase activity,molecular_function
60363,GO:0004802,Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.,transketolase activity,molecular_function
60364,GO:0004803,Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.,transposase activity,molecular_function
60365,GO:0004805,"Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate.",trehalose-phosphatase activity,molecular_function
60366,GO:0004806,Catalysis of the reaction: a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H+.,triacylglycerol lipase activity,molecular_function
60367,GO:0004807,Catalysis of the reaction: D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate.,triose-phosphate isomerase activity,molecular_function
60368,GO:0004808,Catalysis of the reaction: 5-aminomethyl-2-thiouridine34 in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine34 in tRNA + H+ + S-adenosyl-L-homocysteine. This enzyme specifically adds the terminal methyl group of 5-[(methylamino)methyl]-2-thiouridylate.,tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity,molecular_function
60369,GO:0004810,Catalysis of the reaction: a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate.,CCA tRNA nucleotidyltransferase activity,molecular_function
60370,GO:0004812,"Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.",aminoacyl-tRNA ligase activity,molecular_function
60371,GO:0004813,Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).,alanine-tRNA ligase activity,molecular_function
60372,GO:0004814,Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).,arginine-tRNA ligase activity,molecular_function
60373,GO:0004815,Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).,aspartate-tRNA ligase activity,molecular_function
60374,GO:0004816,Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.,asparagine-tRNA ligase activity,molecular_function
60375,GO:0004817,Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).,cysteine-tRNA ligase activity,molecular_function
60376,GO:0004818,Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).,glutamate-tRNA ligase activity,molecular_function
60377,GO:0004819,Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).,glutamine-tRNA ligase activity,molecular_function
60378,GO:0004820,Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).,glycine-tRNA ligase activity,molecular_function
60379,GO:0004821,Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).,histidine-tRNA ligase activity,molecular_function
60380,GO:0004822,Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H+.,isoleucine-tRNA ligase activity,molecular_function
60381,GO:0004823,Catalysis of the reaction: leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H+ + Leu-tRNA(Leu).,leucine-tRNA ligase activity,molecular_function
60382,GO:0004824,Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).,lysine-tRNA ligase activity,molecular_function
60383,GO:0004825,Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).,methionine-tRNA ligase activity,molecular_function
60384,GO:0004826,Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).,phenylalanine-tRNA ligase activity,molecular_function
60385,GO:0004827,Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).,proline-tRNA ligase activity,molecular_function
60386,GO:0004828,"Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). Also catalyzes the formation of L-seryl-tRNA(Sec) from tRNA(Sec), the special tRNA for selenocysteine.",serine-tRNA ligase activity,molecular_function
60387,GO:0004829,Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).,threonine-tRNA ligase activity,molecular_function
60388,GO:0004830,Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).,tryptophan-tRNA ligase activity,molecular_function
60389,GO:0004831,Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+.,tyrosine-tRNA ligase activity,molecular_function
60390,GO:0004832,Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H+.,valine-tRNA ligase activity,molecular_function
60391,GO:0004833,Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.,"L-tryptophan 2,3-dioxygenase activity",molecular_function
60392,GO:0004834,"Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.",tryptophan synthase activity,molecular_function
60393,GO:0004835,Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.,tubulin-tyrosine ligase activity,molecular_function
60394,GO:0004836,Catalysis of the reaction: tyramine + L-ascorbate + O2 = (R)-octopamine + L-dehydroascorbate + H2O.,tyramine-beta hydroxylase activity,molecular_function
60395,GO:0004837,Catalysis of the reaction: L-tyrosine = tyramine + CO2.,tyrosine decarboxylase activity,molecular_function
60396,GO:0004838,Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 3-(4-hydroxyphenyl)pyruvate + L-glutamate.,L-tyrosine:2-oxoglutarate transaminase activity,molecular_function
60397,GO:0004839,"Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.",ubiquitin activating enzyme activity,molecular_function
60398,GO:0004842,"Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.",ubiquitin-protein transferase activity,molecular_function
60399,GO:0004843,An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.,cysteine-type deubiquitinase activity,molecular_function
60400,GO:0004844,"Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.",uracil DNA N-glycosylase activity,molecular_function
60401,GO:0004845,Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.,uracil phosphoribosyltransferase activity,molecular_function
60402,GO:0004846,Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + H2O2.,urate oxidase activity,molecular_function
60403,GO:0004847,Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H+ + phosphate + urea-1-carboxylate.,urea carboxylase activity,molecular_function
60404,GO:0004848,Catalysis of the reaction: (S)-ureidoglycolate + H2O + 2 H+ = CO2 + glyoxylate + 2 NH4.,ureidoglycolate hydrolase activity,molecular_function
60405,GO:0004849,Catalysis of the reaction: ATP + uridine = ADP + UMP.,uridine kinase activity,molecular_function
60406,GO:0004850,Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,uridine phosphorylase activity,molecular_function
60407,GO:0004851,Catalysis of the reaction: uroporphyrinogen III + 2 S-adenosyl-L-methionine = precorrin-2 + 2 S-adenosyl-L-homocysteine + H+.,uroporphyrin-III C-methyltransferase activity,molecular_function
60408,GO:0004852,Catalysis of the reaction: hydroxymethylbilane = H2O + uroporphyrinogen III.,uroporphyrinogen-III synthase activity,molecular_function
60409,GO:0004853,Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.,uroporphyrinogen decarboxylase activity,molecular_function
60410,GO:0004854,Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.,xanthine dehydrogenase activity,molecular_function
60411,GO:0004855,Catalysis of the reaction: xanthine + H2O + O2 = urate + H2O2.,xanthine oxidase activity,molecular_function
60412,GO:0004856,Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H+.,D-xylulokinase activity,molecular_function
60413,GO:0004857,A molecular function regulator that reduces a catalytic activity.,enzyme inhibitor activity,molecular_function
60414,GO:0004858,"Binds to and stops, prevents or reduces the activity of dUTP pyrophosphatase.",dUTP pyrophosphatase inhibitor activity,molecular_function
60415,GO:0004859,"Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.",phospholipase inhibitor activity,molecular_function
60416,GO:0004860,"Binds to and stops, prevents or reduces the activity of a protein kinase.",protein kinase inhibitor activity,molecular_function
60417,GO:0004861,"Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.",cyclin-dependent protein serine/threonine kinase inhibitor activity,molecular_function
60418,GO:0004862,"Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.",cAMP-dependent protein kinase inhibitor activity,molecular_function
60419,GO:0004864,"Binds to and stops, prevents or reduces the activity of a protein phosphatase.",protein phosphatase inhibitor activity,molecular_function
60420,GO:0004865,"Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.",protein serine/threonine phosphatase inhibitor activity,molecular_function
60421,GO:0004866,"Binds to and stops, prevents or reduces the activity of an endopeptidase.",endopeptidase inhibitor activity,molecular_function
60422,GO:0004867,"Binds to and stops, prevents or reduces the activity of a serine-type endopeptidase.",serine-type endopeptidase inhibitor activity,molecular_function
60423,GO:0004869,"Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase.",cysteine-type endopeptidase inhibitor activity,molecular_function
60424,GO:0004873,"Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the r...",asialoglycoprotein receptor activity,molecular_function
60425,GO:0004875,Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement receptor activity,molecular_function
60426,GO:0004876,Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C3a receptor activity,molecular_function
60427,GO:0004877,Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C3b receptor activity,molecular_function
60428,GO:0004878,Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,complement component C5a receptor activity,molecular_function
60429,GO:0004879,"A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.",nuclear receptor activity,molecular_function
60430,GO:0004883,A nuclear receptor activity regulated by glucocorticoid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.,nuclear glucocorticoid receptor activity,molecular_function
60431,GO:0004888,Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.,transmembrane signaling receptor activity,molecular_function
60432,GO:0004890,"Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.",GABA-A receptor activity,molecular_function
60433,GO:0004895,"The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins.",cell adhesion receptor activity,molecular_function
60434,GO:0004896,Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,cytokine receptor activity,molecular_function
60435,GO:0004897,Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,ciliary neurotrophic factor receptor activity,molecular_function
60436,GO:0004900,Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,erythropoietin receptor activity,molecular_function
60437,GO:0004901,Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,granulocyte macrophage colony-stimulating factor receptor activity,molecular_function
60438,GO:0004902,Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,granulocyte colony-stimulating factor receptor activity,molecular_function
60439,GO:0004903,Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,growth hormone receptor activity,molecular_function
60440,GO:0004904,Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interferon receptor activity,molecular_function
60441,GO:0004905,"Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.",type I interferon receptor activity,molecular_function
60442,GO:0004906,Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,type II interferon receptor activity,molecular_function
60443,GO:0004908,Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.,interleukin-1 receptor activity,molecular_function
60444,GO:0004909,Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins.,"interleukin-1, type I, activating receptor activity",molecular_function
60445,GO:0004910,Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors.,"interleukin-1, type II, blocking receptor activity",molecular_function
60446,GO:0004911,Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-2 receptor activity,molecular_function
60447,GO:0004912,Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-3 receptor activity,molecular_function
60448,GO:0004913,Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-4 receptor activity,molecular_function
60449,GO:0004914,Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-5 receptor activity,molecular_function
60450,GO:0004915,Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-6 receptor activity,molecular_function
60451,GO:0004917,Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-7 receptor activity,molecular_function
60452,GO:0004918,Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-8 receptor activity,molecular_function
60453,GO:0004919,Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-9 receptor activity,molecular_function
60454,GO:0004920,Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-10 receptor activity,molecular_function
60455,GO:0004921,Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-11 receptor activity,molecular_function
60456,GO:0004923,Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,leukemia inhibitory factor receptor activity,molecular_function
60457,GO:0004924,Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,oncostatin-M receptor activity,molecular_function
60458,GO:0004925,Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,prolactin receptor activity,molecular_function
60459,GO:0004930,Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled receptor activity,molecular_function
60460,GO:0004931,Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,extracellularly ATP-gated monoatomic cation channel activity,molecular_function
60461,GO:0004932,Combining with a mating-type factor pheromone to initiate a change in cell activity.,mating-type factor pheromone receptor activity,molecular_function
60462,GO:0004933,Combining with the mating-type a-factor pheromone to initiate a change in cell activity.,mating-type a-factor pheromone receptor activity,molecular_function
60463,GO:0004934,Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.,mating-type alpha-factor pheromone receptor activity,molecular_function
60464,GO:0004935,Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.,adrenergic receptor activity,molecular_function
60465,GO:0004936,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.",alpha-adrenergic receptor activity,molecular_function
60466,GO:0004937,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.",alpha1-adrenergic receptor activity,molecular_function
60467,GO:0004938,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.",alpha2-adrenergic receptor activity,molecular_function
60468,GO:0004939,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.",beta-adrenergic receptor activity,molecular_function
60469,GO:0004940,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.",beta1-adrenergic receptor activity,molecular_function
60470,GO:0004941,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.",beta2-adrenergic receptor activity,molecular_function
60471,GO:0004945,"An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.",angiotensin type II receptor activity,molecular_function
60472,GO:0004946,Combining with bombesin to initiate a change in cell activity.,bombesin receptor activity,molecular_function
60473,GO:0004947,Combining with bradykinin to initiate a change in cell activity.,bradykinin receptor activity,molecular_function
60474,GO:0004948,Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,calcitonin receptor activity,molecular_function
60475,GO:0004949,Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.,cannabinoid receptor activity,molecular_function
60476,GO:0004950,"Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune resp...",chemokine receptor activity,molecular_function
60477,GO:0004951,Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.,cholecystokinin receptor activity,molecular_function
60478,GO:0004952,Combining with the neurotransmitter dopamine to initiate a change in cell activity.,dopamine neurotransmitter receptor activity,molecular_function
60479,GO:0004953,Combining with an icosanoid to initiate a change in cell activity.,icosanoid receptor activity,molecular_function
60480,GO:0004954,"Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity.",prostanoid receptor activity,molecular_function
60481,GO:0004955,Combining with a prostaglandin (PG) to initiate a change in cell activity.,prostaglandin receptor activity,molecular_function
60482,GO:0004956,Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.,prostaglandin D receptor activity,molecular_function
60483,GO:0004957,Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.,prostaglandin E receptor activity,molecular_function
60484,GO:0004958,Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.,prostaglandin F receptor activity,molecular_function
60485,GO:0004960,Combining with a thromboxane (TXA) to initiate a change in cell activity.,thromboxane receptor activity,molecular_function
60486,GO:0004961,Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.,thromboxane A2 receptor activity,molecular_function
60487,GO:0004962,Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,endothelin receptor activity,molecular_function
60488,GO:0004963,Combining with follicle-stimulating hormone to initiate a change in cell activity.,follicle-stimulating hormone receptor activity,molecular_function
60489,GO:0004964,Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.,luteinizing hormone receptor activity,molecular_function
60490,GO:0004965,"Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.",G protein-coupled GABA receptor activity,molecular_function
60491,GO:0004966,Combining with galanin to initiate a change in cell activity.,galanin receptor activity,molecular_function
60492,GO:0004967,Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,glucagon receptor activity,molecular_function
60493,GO:0004968,Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.,gonadotropin-releasing hormone receptor activity,molecular_function
60494,GO:0004969,"Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine receptor activity,molecular_function
60495,GO:0004970,Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.,glutamate-gated receptor activity,molecular_function
60496,GO:0004971,"An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.",AMPA glutamate receptor activity,molecular_function
60497,GO:0004972,"A cation channel that opens in response to binding by extracellular glutmate, but only if glycine or D-serine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.",NMDA glutamate receptor activity,molecular_function
60498,GO:0004974,Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine.,leukotriene receptor activity,molecular_function
60499,GO:0004977,Combining with melanocortin to initiate a change in cell activity.,melanocortin receptor activity,molecular_function
60500,GO:0004978,Combining with corticotropin to initiate a change in cell activity.,corticotropin receptor activity,molecular_function
60501,GO:0004979,"Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).",beta-endorphin receptor activity,molecular_function
60502,GO:0004980,Combining with melanocyte-stimulating hormone to initiate a change in cell activity.,melanocyte-stimulating hormone receptor activity,molecular_function
60503,GO:0004982,Combining with an N-formyl peptide to initiate a change in cell activity.,N-formyl peptide receptor activity,molecular_function
60504,GO:0004983,Combining with neuropeptide Y to initiate a change in cell activity.,neuropeptide Y receptor activity,molecular_function
60505,GO:0004984,Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.,olfactory receptor activity,molecular_function
60506,GO:0004985,"Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.",G protein-coupled opioid receptor activity,molecular_function
60507,GO:0004989,Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.,octopamine receptor activity,molecular_function
60508,GO:0004990,Combining with oxytocin to initiate a change in cell activity.,oxytocin receptor activity,molecular_function
60509,GO:0004991,Combining with parathyroid hormone to initiate a change in cell activity.,parathyroid hormone receptor activity,molecular_function
60510,GO:0004992,Combining with platelet activating factor to initiate a change in cell activity.,platelet activating factor receptor activity,molecular_function
60511,GO:0004993,Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.,G protein-coupled serotonin receptor activity,molecular_function
60512,GO:0004994,Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).,somatostatin receptor activity,molecular_function
60513,GO:0004995,Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.,tachykinin receptor activity,molecular_function
60514,GO:0004996,Combining with thyroid-stimulating hormone to initiate a change in cell activity.,thyroid-stimulating hormone receptor activity,molecular_function
60515,GO:0004997,Combining with thyrotropin-releasing hormone to initiate a change in cell activity.,thyrotropin-releasing hormone receptor activity,molecular_function
60516,GO:0004998,"Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.",transferrin receptor activity,molecular_function
60517,GO:0004999,Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.,vasoactive intestinal polypeptide receptor activity,molecular_function
60518,GO:0005000,Combining with vasopressin to initiate a change in cell activity.,vasopressin receptor activity,molecular_function
60519,GO:0005001,Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.,transmembrane receptor protein tyrosine phosphatase activity,molecular_function
60520,GO:0005003,Combining with an ephrin receptor ligand to initiate a change in cell activity.,ephrin receptor activity,molecular_function
60521,GO:0005004,Combining with a GPI-anchored ephrin to initiate a change in cell activity.,GPI-linked ephrin receptor activity,molecular_function
60522,GO:0005005,Combining with a transmembrane ephrin to initiate a change in cell activity.,transmembrane-ephrin receptor activity,molecular_function
60523,GO:0005006,Combining with an epidermal growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,epidermal growth factor receptor activity,molecular_function
60524,GO:0005007,Combining with a fibroblast growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,fibroblast growth factor receptor activity,molecular_function
60525,GO:0005008,Combining with hepatocyte growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,hepatocyte growth factor receptor activity,molecular_function
60526,GO:0005009,Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,insulin receptor activity,molecular_function
60527,GO:0005010,Combining with insulin-like growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,insulin-like growth factor receptor activity,molecular_function
60528,GO:0005011,Combining with macrophage colony-stimulating factor (M-CSF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.,macrophage colony-stimulating factor receptor activity,molecular_function
60529,GO:0005017,Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,platelet-derived growth factor receptor activity,molecular_function
60530,GO:0005018,"Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.",platelet-derived growth factor alpha-receptor activity,molecular_function
60531,GO:0005019,Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.,platelet-derived growth factor beta-receptor activity,molecular_function
60532,GO:0005020,Combining with stem cell factor (SCF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.,stem cell factor receptor activity,molecular_function
60533,GO:0005021,Combining with a vascular endothelial growth factor (VEGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,vascular endothelial growth factor receptor activity,molecular_function
60534,GO:0005024,"Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.",transforming growth factor beta receptor activity,molecular_function
60535,GO:0005025,"Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.","transforming growth factor beta receptor activity, type I",molecular_function
60536,GO:0005026,"Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor.","transforming growth factor beta receptor activity, type II",molecular_function
60537,GO:0005030,"Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.",neurotrophin receptor activity,molecular_function
60538,GO:0005031,"Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.",tumor necrosis factor receptor activity,molecular_function
60539,GO:0005034,"Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.",osmosensor activity,molecular_function
60540,GO:0005035,"Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.",death receptor activity,molecular_function
60541,GO:0005041,Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.,low-density lipoprotein particle receptor activity,molecular_function
60542,GO:0005042,Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,netrin receptor activity,molecular_function
60543,GO:0005043,Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.,netrin receptor activity involved in chemorepulsion,molecular_function
60544,GO:0005044,"Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).",scavenger receptor activity,molecular_function
60545,GO:0005047,Binding to a signal recognition particle.,signal recognition particle binding,molecular_function
60546,GO:0005048,"Binding to a signal sequence, a short stretch of amino acids found in a protein that acts as a signal for its proper localization in the cell.",signal sequence receptor activity,molecular_function
60547,GO:0005049,"Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.",nuclear export signal receptor activity,molecular_function
60548,GO:0005055,"Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity.",laminin receptor activity,molecular_function
60549,GO:0005056,"Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",tiggrin receptor activity,molecular_function
60550,GO:0005068,"The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.",transmembrane receptor protein tyrosine kinase adaptor activity,molecular_function
60551,GO:0005078,"The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.",MAP kinase scaffold activity,molecular_function
60552,GO:0005080,Binding to protein kinase C.,protein kinase C binding,molecular_function
60553,GO:0005085,"Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.",guanyl-nucleotide exchange factor activity,molecular_function
60554,GO:0005091,"The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.",guanyl-nucleotide exchange factor adaptor activity,molecular_function
60555,GO:0005092,"Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.",GDP-dissociation inhibitor activity,molecular_function
60556,GO:0005093,"Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.",Rab GDP-dissociation inhibitor activity,molecular_function
60557,GO:0005094,"Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.",Rho GDP-dissociation inhibitor activity,molecular_function
60558,GO:0005095,"Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.",GTPase inhibitor activity,molecular_function
60559,GO:0005096,"Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.",GTPase activator activity,molecular_function
60560,GO:0005102,"Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.",signaling receptor binding,molecular_function
60561,GO:0005104,Binding to a fibroblast growth factor receptor (FGFR).,fibroblast growth factor receptor binding,molecular_function
60562,GO:0005105,Binding to a type 1 fibroblast growth factor receptor (FGFR1).,type 1 fibroblast growth factor receptor binding,molecular_function
60563,GO:0005109,Binding to a frizzled (fz) receptor.,frizzled binding,molecular_function
60564,GO:0005111,Binding to a type 2 fibroblast growth factor receptor (FGFR2).,type 2 fibroblast growth factor receptor binding,molecular_function
60565,GO:0005112,"Binding to a Notch (N) protein, a surface receptor.",Notch binding,molecular_function
60566,GO:0005113,"Binding to a patched (ptc) protein, a receptor for hedgehog proteins.",patched binding,molecular_function
60567,GO:0005114,Binding to a type II transforming growth factor beta receptor.,type II transforming growth factor beta receptor binding,molecular_function
60568,GO:0005115,Binding to a receptor tyrosine kinase-like orphan receptor (Ror).,receptor tyrosine kinase-like orphan receptor binding,molecular_function
60569,GO:0005117,"Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor.",wishful thinking binding,molecular_function
60570,GO:0005118,"Binding to a sevenless (sev) protein, a receptor tyrosine kinase.",sevenless binding,molecular_function
60571,GO:0005119,"Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.",smoothened binding,molecular_function
60572,GO:0005121,"Binding to a Toll protein, a transmembrane receptor.",Toll binding,molecular_function
60573,GO:0005122,"Binding to a torso (tor) protein, a receptor tyrosine kinase.",torso binding,molecular_function
60574,GO:0005123,Binding to a member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).,death receptor binding,molecular_function
60575,GO:0005124,"Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.",scavenger receptor binding,molecular_function
60576,GO:0005125,"The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.",cytokine activity,molecular_function
60577,GO:0005126,Binding to a cytokine receptor.,cytokine receptor binding,molecular_function
60578,GO:0005127,Binding to a ciliary neurotrophic factor receptor.,ciliary neurotrophic factor receptor binding,molecular_function
60579,GO:0005128,Binding to an erythropoietin receptor.,erythropoietin receptor binding,molecular_function
60580,GO:0005129,Binding to a granulocyte macrophage colony-stimulating factor receptor.,granulocyte macrophage colony-stimulating factor receptor binding,molecular_function
60581,GO:0005130,Binding to a granulocyte colony-stimulating factor receptor.,granulocyte colony-stimulating factor receptor binding,molecular_function
60582,GO:0005131,Binding to a growth hormone receptor.,growth hormone receptor binding,molecular_function
60583,GO:0005132,"Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).",type I interferon receptor binding,molecular_function
60584,GO:0005133,Binding to a type II interferon receptor. Type II interferon is also known as interferon-gamma.,type II interferon receptor binding,molecular_function
60585,GO:0005134,Binding to an interleukin-2 receptor.,interleukin-2 receptor binding,molecular_function
60586,GO:0005135,Binding to an interleukin-3 receptor.,interleukin-3 receptor binding,molecular_function
60587,GO:0005136,Binding to an interleukin-4 receptor.,interleukin-4 receptor binding,molecular_function
60588,GO:0005137,Binding to an interleukin-5 receptor.,interleukin-5 receptor binding,molecular_function
60589,GO:0005138,Binding to an interleukin-6 receptor.,interleukin-6 receptor binding,molecular_function
60590,GO:0005139,Binding to an interleukin-7 receptor.,interleukin-7 receptor binding,molecular_function
60591,GO:0005140,Binding to an interleukin-9 receptor.,interleukin-9 receptor binding,molecular_function
60592,GO:0005141,Binding to an interleukin-10 receptor.,interleukin-10 receptor binding,molecular_function
60593,GO:0005142,Binding to an interleukin-11 receptor.,interleukin-11 receptor binding,molecular_function
60594,GO:0005143,Binding to an interleukin-12 receptor.,interleukin-12 receptor binding,molecular_function
60595,GO:0005144,Binding to an interleukin-13 receptor.,interleukin-13 receptor binding,molecular_function
60596,GO:0005146,Binding to an leukemia inhibitory factor receptor.,leukemia inhibitory factor receptor binding,molecular_function
60597,GO:0005147,Binding to an oncostatin-M receptor.,oncostatin-M receptor binding,molecular_function
60598,GO:0005148,Binding to a prolactin receptor.,prolactin receptor binding,molecular_function
60599,GO:0005149,Binding to an interleukin-1 receptor.,interleukin-1 receptor binding,molecular_function
60600,GO:0005150,Binding to a Type I interleukin-1 receptor.,"interleukin-1, type I receptor binding",molecular_function
60601,GO:0005151,Binding to a Type II interleukin-1 receptor.,"interleukin-1, type II receptor binding",molecular_function
60602,GO:0005152,Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.,interleukin-1 receptor antagonist activity,molecular_function
60603,GO:0005153,Binding to an interleukin-8 receptor.,interleukin-8 receptor binding,molecular_function
60604,GO:0005154,Binding to an epidermal growth factor receptor.,epidermal growth factor receptor binding,molecular_function
60605,GO:0005157,Binding to a macrophage colony-stimulating factor receptor.,macrophage colony-stimulating factor receptor binding,molecular_function
60606,GO:0005158,Binding to an insulin receptor.,insulin receptor binding,molecular_function
60607,GO:0005159,Binding to an insulin-like growth factor receptor.,insulin-like growth factor receptor binding,molecular_function
60608,GO:0005160,Binding to a transforming growth factor beta receptor.,transforming growth factor beta receptor binding,molecular_function
60609,GO:0005161,Binding to a platelet-derived growth factor receptor.,platelet-derived growth factor receptor binding,molecular_function
60610,GO:0005163,Binding to a nerve growth factor receptor.,nerve growth factor receptor binding,molecular_function
60611,GO:0005164,Binding to a tumor necrosis factor receptor.,tumor necrosis factor receptor binding,molecular_function
60612,GO:0005165,Binding to a neurotrophin receptor.,neurotrophin receptor binding,molecular_function
60613,GO:0005166,Binding to a neurotrophin p75 receptor.,neurotrophin p75 receptor binding,molecular_function
60614,GO:0005167,Binding to a neurotrophin TRK receptor.,neurotrophin TRK receptor binding,molecular_function
60615,GO:0005168,Binding to a neurotrophin TRKA receptor.,neurotrophin TRKA receptor binding,molecular_function
60616,GO:0005169,Binding to a neurotrophin TRKB receptor.,neurotrophin TRKB receptor binding,molecular_function
60617,GO:0005170,Binding to a neurotrophin TRKC receptor.,neurotrophin TRKC receptor binding,molecular_function
60618,GO:0005171,Binding to an hepatocyte growth factor receptor.,hepatocyte growth factor receptor binding,molecular_function
60619,GO:0005172,Binding to a vascular endothelial growth factor receptor.,vascular endothelial growth factor receptor binding,molecular_function
60620,GO:0005173,"Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.",stem cell factor receptor binding,molecular_function
60621,GO:0005174,"Binding to CD40, a receptor found on the surface of all B-lymphocytes.",CD40 receptor binding,molecular_function
60622,GO:0005175,"Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells.",CD27 receptor binding,molecular_function
60623,GO:0005176,Binding to a protein-tyrosine kinase receptor Neu/ErbB-2/HER2.,ErbB-2 class receptor binding,molecular_function
60624,GO:0005178,Binding to an integrin.,integrin binding,molecular_function
60625,GO:0005179,"The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animal...",hormone activity,molecular_function
60626,GO:0005183,"The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.",gonadotropin hormone-releasing hormone activity,molecular_function
60627,GO:0005184,"The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.",neuropeptide hormone activity,molecular_function
60628,GO:0005185,"The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin.",neurohypophyseal hormone activity,molecular_function
60629,GO:0005186,"The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.",pheromone activity,molecular_function
60630,GO:0005198,The action of a molecule that contributes to the structural integrity of a complex.,structural molecule activity,molecular_function
60631,GO:0005199,The action of a molecule that contributes to the structural integrity of a cell wall.,structural constituent of cell wall,molecular_function
60632,GO:0005200,The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.,structural constituent of cytoskeleton,molecular_function
60633,GO:0005201,The action of a molecule that contributes to the structural integrity of the extracellular matrix.,extracellular matrix structural constituent,molecular_function
60634,GO:0005212,The action of a molecule that contributes to the structural integrity of the lens of an eye.,structural constituent of eye lens,molecular_function
60635,GO:0005213,The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.,structural constituent of egg chorion,molecular_function
60636,GO:0005214,The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.,structural constituent of chitin-based cuticle,molecular_function
60637,GO:0005215,"Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.",transporter activity,molecular_function
60638,GO:0005216,Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).,monoatomic ion channel activity,molecular_function
60639,GO:0005217,Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.,intracellularly ligand-gated monoatomic ion channel activity,molecular_function
60640,GO:0005219,Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration and is sensitive to the plant alkaloid ryanodine.,ryanodine-sensitive calcium-release channel activity,molecular_function
60641,GO:0005220,"Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.","inositol 1,4,5-trisphosphate-gated calcium channel activity",molecular_function
60642,GO:0005221,Enables the transmembrane transfer of a monoatomic cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.,intracellularly cyclic nucleotide-activated monoatomic cation channel activity,molecular_function
60643,GO:0005222,Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.,intracellularly cAMP-activated cation channel activity,molecular_function
60644,GO:0005223,Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.,intracellularly cGMP-activated cation channel activity,molecular_function
60645,GO:0005225,Enables the transmembrane transfer of a monoatomic anion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.,volume-sensitive anion channel activity,molecular_function
60646,GO:0005227,Enables the transmembrane transfer of an inorganic cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts.,calcium-activated cation channel activity,molecular_function
60647,GO:0005228,"Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single c...",intracellular sodium-activated potassium channel activity,molecular_function
60648,GO:0005229,"Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.",intracellularly calcium-gated chloride channel activity,molecular_function
60649,GO:0005230,Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.,extracellular ligand-gated monoatomic ion channel activity,molecular_function
60650,GO:0005231,"Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.",excitatory extracellular ligand-gated monoatomic ion channel activity,molecular_function
60651,GO:0005234,Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,extracellularly glutamate-gated ion channel activity,molecular_function
60652,GO:0005237,"Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.",inhibitory extracellular ligand-gated monoatomic ion channel activity,molecular_function
60653,GO:0005242,"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ eq...",inward rectifier potassium channel activity,molecular_function
60654,GO:0005243,"A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.",gap junction channel activity,molecular_function
60655,GO:0005244,Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated monoatomic ion channel activity,molecular_function
60656,GO:0005245,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated calcium channel activity,molecular_function
60657,GO:0005246,Modulates the activity of a calcium channel.,calcium channel regulator activity,molecular_function
60658,GO:0005247,Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated chloride channel activity,molecular_function
60659,GO:0005248,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity,molecular_function
60660,GO:0005249,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity,molecular_function
60661,GO:0005250,Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.,A-type (transient outward) potassium channel activity,molecular_function
60662,GO:0005251,"Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.",delayed rectifier potassium channel activity,molecular_function
60663,GO:0005252,Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.,open rectifier potassium channel activity,molecular_function
60664,GO:0005253,Enables the energy-independent facilitated diffusion of a monoatomic anion through a transmembrane aqueous pore or channel.,monoatomic anion channel activity,molecular_function
60665,GO:0005254,Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane aqueous pore or channel.,chloride channel activity,molecular_function
60666,GO:0005260,Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.,intracellularly ATP-gated chloride channel activity,molecular_function
60667,GO:0005261,Enables the energy-independent facilitated diffusion of a monoatomic cation through a transmembrane aqueous pore or channel.,monoatomic cation channel activity,molecular_function
60668,GO:0005262,Enables the energy-independent facilitated diffusion of a calcium ion through a transmembrane aqueous pore or channel.,calcium channel activity,molecular_function
60669,GO:0005267,Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel.,potassium channel activity,molecular_function
60670,GO:0005272,Enables the energy-independent facilitated diffusion of a sodium ion through a transmembrane aqueous pore or channel.,sodium channel activity,molecular_function
60671,GO:0005274,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.,allantoin:proton symporter activity,molecular_function
60672,GO:0005275,"Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.",amine transmembrane transporter activity,molecular_function
60673,GO:0005277,"Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.",acetylcholine transmembrane transporter activity,molecular_function
60674,GO:0005278,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out).,acetylcholine:proton antiporter activity,molecular_function
60675,GO:0005280,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).,amino acid:proton symporter activity,molecular_function
60676,GO:0005283,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).,amino acid:sodium symporter activity,molecular_function
60677,GO:0005287,Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity basic amino acid transmembrane transporter activity,molecular_function
60678,GO:0005289,Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity L-arginine transmembrane transporter activity,molecular_function
60679,GO:0005290,Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.,L-histidine transmembrane transporter activity,molecular_function
60680,GO:0005291,Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity L-histidine transmembrane transporter activity,molecular_function
60681,GO:0005292,Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity lysine transmembrane transporter activity,molecular_function
60682,GO:0005294,"Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",neutral L-amino acid secondary active transmembrane transporter activity,molecular_function
60683,GO:0005295,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) = neutral L-amino acid(in) + Na+(in).,neutral L-amino acid:sodium symporter activity,molecular_function
60684,GO:0005297,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).,proline:proton symporter activity,molecular_function
60685,GO:0005298,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).,proline:sodium symporter activity,molecular_function
60686,GO:0005300,Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity tryptophan transmembrane transporter activity,molecular_function
60687,GO:0005302,Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid.,L-tyrosine transmembrane transporter activity,molecular_function
60688,GO:0005304,Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.,L-valine transmembrane transporter activity,molecular_function
60689,GO:0005307,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in).,choline:sodium symporter activity,molecular_function
60690,GO:0005308,"Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.",creatine transmembrane transporter activity,molecular_function
60691,GO:0005309,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).,creatine:sodium symporter activity,molecular_function
60692,GO:0005310,Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.,dicarboxylic acid transmembrane transporter activity,molecular_function
60693,GO:0005313,Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.,L-glutamate transmembrane transporter activity,molecular_function
60694,GO:0005314,Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity L-glutamate transmembrane transporter activity,molecular_function
60695,GO:0005315,"Enables the transfer of phosphate ions from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",phosphate transmembrane transporter activity,molecular_function
60696,GO:0005316,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction:phosphate(out) + Na+(out) = phosphate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity phosphate:sodium symporter activity,molecular_function
60697,GO:0005319,Directly binding to a specific lipid and delivering it either to an acceptor molecule or to a specific location.,lipid carrier activity,molecular_function
60698,GO:0005324,Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid transmembrane transporter activity,molecular_function
60699,GO:0005326,"Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.",neurotransmitter transmembrane transporter activity,molecular_function
60700,GO:0005328,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).,neurotransmitter:sodium symporter activity,molecular_function
60701,GO:0005330,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).,dopamine:sodium symporter activity,molecular_function
60702,GO:0005332,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) + Cl-(out) = gamma-aminobutyric acid(in) + Na+(in) + Cl(in).,gamma-aminobutyric acid:sodium:chloride symporter activity,molecular_function
60703,GO:0005334,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).,norepinephrine:sodium symporter activity,molecular_function
60704,GO:0005335,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).,serotonin:sodium:chloride symporter activity,molecular_function
60705,GO:0005337,"Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.",nucleoside transmembrane transporter activity,molecular_function
60706,GO:0005338,Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.,nucleotide-sugar transmembrane transporter activity,molecular_function
60707,GO:0005340,Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.,nucleotide-sulfate transmembrane transporter activity,molecular_function
60708,GO:0005343,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).,organic acid:sodium symporter activity,molecular_function
60709,GO:0005344,Binding to oxygen and delivering it to an acceptor molecule or a specific location.,oxygen carrier activity,molecular_function
60710,GO:0005345,"Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.",purine nucleobase transmembrane transporter activity,molecular_function
60711,GO:0005346,"Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.",purine ribonucleotide transmembrane transporter activity,molecular_function
60712,GO:0005347,"Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.",ATP transmembrane transporter activity,molecular_function
60713,GO:0005350,"Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.",pyrimidine nucleobase transmembrane transporter activity,molecular_function
60714,GO:0005351,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in).,carbohydrate:proton symporter activity,molecular_function
60715,GO:0005352,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.",alpha-glucoside:proton symporter activity,molecular_function
60716,GO:0005353,Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.,fructose transmembrane transporter activity,molecular_function
60717,GO:0005354,"Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.",galactose transmembrane transporter activity,molecular_function
60718,GO:0005356,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.,D-glucose:proton symporter activity,molecular_function
60719,GO:0005358,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In hi...",high-affinity D-glucose:proton symporter activity,molecular_function
60720,GO:0005359,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked t...,low-affinity D-glucose:proton symporter activity,molecular_function
60721,GO:0005360,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.",insulin-responsive D-glucose:proton symporter activity,molecular_function
60722,GO:0005362,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity D-glucose:sodium symporter activity,molecular_function
60723,GO:0005363,"Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.",maltose transmembrane transporter activity,molecular_function
60724,GO:0005364,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in).,maltose:proton symporter activity,molecular_function
60725,GO:0005365,"Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.",myo-inositol transmembrane transporter activity,molecular_function
60726,GO:0005366,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).,myo-inositol:proton symporter activity,molecular_function
60727,GO:0005367,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in).,myo-inositol:sodium symporter activity,molecular_function
60728,GO:0005368,Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.,taurine transmembrane transporter activity,molecular_function
60729,GO:0005369,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).,taurine:sodium symporter activity,molecular_function
60730,GO:0005371,"Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",tricarboxylate secondary active transmembrane transporter activity,molecular_function
60731,GO:0005372,Enables the transfer of water (H2O) from one side of a membrane to the other.,water transmembrane transporter activity,molecular_function
60732,GO:0005375,Enables the transfer of copper (Cu) ions from one side of a membrane to the other.,copper ion transmembrane transporter activity,molecular_function
60733,GO:0005381,Enables the transfer of iron (Fe) ions from one side of a membrane to the other.,iron ion transmembrane transporter activity,molecular_function
60734,GO:0005384,Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.,manganese ion transmembrane transporter activity,molecular_function
60735,GO:0005385,Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.,zinc ion transmembrane transporter activity,molecular_function
60736,GO:0005388,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(in) = ADP + phosphate + Ca2+(out).,P-type calcium transporter activity,molecular_function
60737,GO:0005391,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).,P-type sodium:potassium-exchanging transporter activity,molecular_function
60738,GO:0005402,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).,carbohydrate:monoatomic cation symporter activity,molecular_function
60739,GO:0005412,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).,D-glucose:sodium symporter activity,molecular_function
60740,GO:0005415,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).,nucleoside:sodium symporter activity,molecular_function
60741,GO:0005416,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in).,amino acid:monoatomic cation symporter activity,molecular_function
60742,GO:0005427,"Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.",proton-dependent oligopeptide secondary active transmembrane transporter activity,molecular_function
60743,GO:0005432,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).,calcium:sodium antiporter activity,molecular_function
60744,GO:0005436,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).,sodium:phosphate symporter activity,molecular_function
60745,GO:0005452,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).,solute:inorganic anion antiporter activity,molecular_function
60746,GO:0005456,Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other.,CMP-N-acetylneuraminate transmembrane transporter activity,molecular_function
60747,GO:0005457,Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.,GDP-fucose transmembrane transporter activity,molecular_function
60748,GO:0005458,Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.,GDP-mannose transmembrane transporter activity,molecular_function
60749,GO:0005459,Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.,UDP-galactose transmembrane transporter activity,molecular_function
60750,GO:0005460,Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.,UDP-glucose transmembrane transporter activity,molecular_function
60751,GO:0005461,Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.,UDP-glucuronate transmembrane transporter activity,molecular_function
60752,GO:0005462,"Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylglucosamine transmembrane transporter activity,molecular_function
60753,GO:0005463,"Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylgalactosamine transmembrane transporter activity,molecular_function
60754,GO:0005464,Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.,UDP-xylose transmembrane transporter activity,molecular_function
60755,GO:0005469,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).,succinate:fumarate antiporter activity,molecular_function
60756,GO:0005471,Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).,ATP:ADP antiporter activity,molecular_function
60757,GO:0005476,Catalysis of the reaction: carnitine (mitochondrial) + O-acyl-L-carnitine (cytoplasm) = carnitine (cytoplasm) + O-acyl-L-carnitine (mitochondrial).,carnitine:O-acyl-L-carnitine antiporter activity,molecular_function
60758,GO:0005477,"Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",pyruvate secondary active transmembrane transporter activity,molecular_function
60759,GO:0005483,"Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.",soluble NSF attachment protein activity,molecular_function
60760,GO:0005484,Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.,SNAP receptor activity,molecular_function
60761,GO:0005488,"The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.",binding,molecular_function
60762,GO:0005496,"Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.",steroid binding,molecular_function
60763,GO:0005497,"Binding to an androgen, a male sex hormone.",androgen binding,molecular_function
60764,GO:0005499,"Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",vitamin D binding,molecular_function
60765,GO:0005500,"Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.",juvenile hormone binding,molecular_function
60766,GO:0005501,"Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.",retinoid binding,molecular_function
60767,GO:0005502,"Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.",11-cis retinal binding,molecular_function
60768,GO:0005503,"Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.",all-trans retinal binding,molecular_function
60769,GO:0005504,"Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.",fatty acid binding,molecular_function
60770,GO:0005506,Binding to an iron (Fe) ion.,iron ion binding,molecular_function
60771,GO:0005507,Binding to a copper (Cu) ion.,copper ion binding,molecular_function
60772,GO:0005509,Binding to a calcium ion (Ca2+).,calcium ion binding,molecular_function
60773,GO:0005513,The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.,detection of calcium ion,biological_process
60774,GO:0005515,Binding to a protein.,protein binding,molecular_function
60775,GO:0005516,"Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.",calmodulin binding,molecular_function
60776,GO:0005518,"Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).",collagen binding,molecular_function
60777,GO:0005519,Binding to a protein involved in modulating the reorganization of the cytoskeleton.,cytoskeletal regulatory protein binding,molecular_function
60778,GO:0005520,"Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.",insulin-like growth factor binding,molecular_function
60779,GO:0005521,Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.,lamin binding,molecular_function
60780,GO:0005522,"Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.",profilin binding,molecular_function
60781,GO:0005523,"Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.",tropomyosin binding,molecular_function
60782,GO:0005524,"Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",ATP binding,molecular_function
60783,GO:0005525,"Binding to GTP, guanosine triphosphate.",GTP binding,molecular_function
60784,GO:0005527,"Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.",macrolide binding,molecular_function
60785,GO:0005528,Binding to a 23-membered macrolide lactone FK506.,FK506 binding,molecular_function
60786,GO:0005534,"Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.",galactose binding,molecular_function
60787,GO:0005536,Binding to D-enantiomers of glucose.,D-glucose binding,molecular_function
60788,GO:0005537,"Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.",D-mannose binding,molecular_function
60789,GO:0005539,Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.,glycosaminoglycan binding,molecular_function
60790,GO:0005540,"Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.",hyaluronic acid binding,molecular_function
60791,GO:0005542,"Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.",folic acid binding,molecular_function
60792,GO:0005543,"Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.",phospholipid binding,molecular_function
60793,GO:0005544,"Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.",calcium-dependent phospholipid binding,molecular_function
60794,GO:0005545,"Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.",1-phosphatidylinositol binding,molecular_function
60795,GO:0005546,"Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.","phosphatidylinositol-4,5-bisphosphate binding",molecular_function
60796,GO:0005547,"Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.","phosphatidylinositol-3,4,5-trisphosphate binding",molecular_function
60797,GO:0005549,"Binding to an odorant, any substance capable of stimulating the sense of smell.",odorant binding,molecular_function
60798,GO:0005550,"Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.",pheromone binding,molecular_function
60799,GO:0005575,"A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the ...",cellular_component,cellular_component
60800,GO:0005576,The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.,extracellular region,cellular_component
60801,GO:0005577,"A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.",fibrinogen complex,cellular_component
60802,GO:0005579,A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.,membrane attack complex,cellular_component
60803,GO:0005581,A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.,collagen trimer,cellular_component
60804,GO:0005582,A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.,collagen type XV trimer,cellular_component
60805,GO:0005583,Any triple helical collagen trimer that forms fibrils.,fibrillar collagen trimer,cellular_component
60806,GO:0005584,A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils.,collagen type I trimer,cellular_component
60807,GO:0005585,A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.,collagen type II trimer,cellular_component
60808,GO:0005586,A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.,collagen type III trimer,cellular_component
60809,GO:0005587,"A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.",collagen type IV trimer,cellular_component
60810,GO:0005588,A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.,collagen type V trimer,cellular_component
60811,GO:0005589,A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.,collagen type VI trimer,cellular_component
60812,GO:0005590,"A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.",collagen type VII trimer,cellular_component
60813,GO:0005591,A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.,collagen type VIII trimer,cellular_component
60814,GO:0005592,A collagen heterotrimer containing type XI and type II alpha chains in alpha1(XI) alpha2(XI) alpha1(II) trimers; type XI collagen triple helices associate to form fibrils.,collagen type XI trimer,cellular_component
60815,GO:0005593,A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.,FACIT collagen trimer,cellular_component
60816,GO:0005594,A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.,collagen type IX trimer,cellular_component
60817,GO:0005595,A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.,collagen type XII trimer,cellular_component
60818,GO:0005596,A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.,collagen type XIV trimer,cellular_component
60819,GO:0005597,A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.,collagen type XVI trimer,cellular_component
60820,GO:0005599,A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).,collagen type X trimer,cellular_component
60821,GO:0005600,A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.,collagen type XIII trimer,cellular_component
60822,GO:0005601,"A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.",classical-complement-pathway C3/C5 convertase complex,cellular_component
60823,GO:0005602,"A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.",complement component C1 complex,cellular_component
60824,GO:0005604,A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.,basement membrane,cellular_component
60825,GO:0005606,"A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.",laminin-111 trimer,cellular_component
60826,GO:0005607,"A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.",laminin-211 trimer,cellular_component
60827,GO:0005608,"A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.",laminin-121 trimer,cellular_component
60828,GO:0005609,"A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.",laminin-221 trimer,cellular_component
60829,GO:0005610,"A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.",laminin-332 trimer,cellular_component
60830,GO:0005611,"A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.",laminin-311 trimer,cellular_component
60831,GO:0005612,"A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.",laminin-321 trimer,cellular_component
60832,GO:0005614,"A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.",interstitial matrix,cellular_component
60833,GO:0005616,"A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.",larval serum protein complex,cellular_component
60834,GO:0005618,"The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.",cell wall,cellular_component
60835,GO:0005619,"The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.",ascospore wall,cellular_component
60836,GO:0005621,Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.,cellular bud scar,cellular_component
60837,GO:0005622,A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.,intracellular anatomical structure,cellular_component
60838,GO:0005628,The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.,prospore membrane,cellular_component
60839,GO:0005630,"The outermost layer of the spore wall, as described in Saccharomyces.",dityrosine layer of spore wall,cellular_component
60840,GO:0005631,"The second outermost layer of the spore wall, as described in Saccharomyces.",chitosan layer of spore wall,cellular_component
60841,GO:0005632,"Either of the two innermost layers of the spore wall, as described in Saccharomyces.",inner layer of spore wall,cellular_component
60842,GO:0005633,Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.,ascus lipid droplet,cellular_component
60843,GO:0005634,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",nucleus,cellular_component
60844,GO:0005635,"The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport.",nuclear envelope,cellular_component
60845,GO:0005637,"The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.",nuclear inner membrane,cellular_component
60846,GO:0005638,"Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.",lamin filament,cellular_component
60847,GO:0005640,"The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.",nuclear outer membrane,cellular_component
60848,GO:0005641,The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.,nuclear envelope lumen,cellular_component
60849,GO:0005642,"Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.",annulate lamellae,cellular_component
60850,GO:0005643,"A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.",nuclear pore,cellular_component
60851,GO:0005652,"The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the mem...",nuclear lamina,cellular_component
60852,GO:0005654,That part of the nuclear content other than the chromosomes or the nucleolus.,nucleoplasm,cellular_component
60853,GO:0005655,"A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.",nucleolar ribonuclease P complex,cellular_component
60854,GO:0005656,"A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.",nuclear pre-replicative complex,cellular_component
60855,GO:0005657,"The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.",replication fork,cellular_component
60856,GO:0005658,"A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a small stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.",alpha DNA polymerase:primase complex,cellular_component
60857,GO:0005662,"A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.",DNA replication factor A complex,cellular_component
60858,GO:0005663,"A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.",DNA replication factor C complex,cellular_component
60859,GO:0005664,A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.,nuclear origin of replication recognition complex,cellular_component
60860,GO:0005665,"RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide rep...","RNA polymerase II, core complex",cellular_component
60861,GO:0005666,"RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymeras...",RNA polymerase III complex,cellular_component
60862,GO:0005667,"A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.",transcription regulator complex,cellular_component
60863,GO:0005668,"A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48.",RNA polymerase transcription factor SL1 complex,cellular_component
60864,GO:0005669,"A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription init...",transcription factor TFIID complex,cellular_component
60865,GO:0005672,"A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).",transcription factor TFIIA complex,cellular_component
60866,GO:0005673,A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.,transcription factor TFIIE complex,cellular_component
60867,GO:0005674,A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.,transcription factor TFIIF complex,cellular_component
60868,GO:0005675,A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.,transcription factor TFIIH holo complex,cellular_component
60869,GO:0005677,Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.,chromatin silencing complex,cellular_component
60870,GO:0005680,"A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.",anaphase-promoting complex,cellular_component
60871,GO:0005681,"Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are ...",spliceosomal complex,cellular_component
60872,GO:0005682,"A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.",U5 snRNP,cellular_component
60873,GO:0005683,A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.,U7 snRNP,cellular_component
60874,GO:0005684,Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.,U2-type spliceosomal complex,cellular_component
60875,GO:0005685,"A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes.",U1 snRNP,cellular_component
60876,GO:0005686,"A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.",U2 snRNP,cellular_component
60877,GO:0005687,"A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.",U4 snRNP,cellular_component
60878,GO:0005688,"A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.",U6 snRNP,cellular_component
60879,GO:0005689,"Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.",U12-type spliceosomal complex,cellular_component
60880,GO:0005690,"A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes.",U4atac snRNP,cellular_component
60881,GO:0005691,"A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes.",U6atac snRNP,cellular_component
60882,GO:0005692,"A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.",U11 snRNP,cellular_component
60883,GO:0005693,"A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes.",U12 snRNP,cellular_component
60884,GO:0005694,A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.,chromosome,cellular_component
60885,GO:0005697,"Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.",telomerase holoenzyme complex,cellular_component
60886,GO:0005700,"A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.",polytene chromosome,cellular_component
60887,GO:0005701,A region at which the centric regions of polytene chromosomes are joined together.,polytene chromosome chromocenter,cellular_component
60888,GO:0005702,"A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.",polytene chromosome weak point,cellular_component
60889,GO:0005703,"A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.",polytene chromosome puff,cellular_component
60890,GO:0005704,"A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.",polytene chromosome band,cellular_component
60891,GO:0005705,"A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.",polytene chromosome interband,cellular_component
60892,GO:0005706,A thread-like connection joining two regions of ectopically paired polytene chromosomes.,polytene chromosome ectopic fiber,cellular_component
60893,GO:0005712,"A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.",chiasma,cellular_component
60894,GO:0005713,An electron dense structure that is associated with meiotic chromosomes.,recombination nodule,cellular_component
60895,GO:0005714,An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.,early recombination nodule,cellular_component
60896,GO:0005715,An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.,late recombination nodule,cellular_component
60897,GO:0005721,Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).,pericentric heterochromatin,cellular_component
60898,GO:0005722,A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.,beta-heterochromatin,cellular_component
60899,GO:0005723,"A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.",alpha-heterochromatin,cellular_component
60900,GO:0005725,Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.,intercalary heterochromatin,cellular_component
60901,GO:0005726,"Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.",perichromatin fibrils,cellular_component
60902,GO:0005727,Circular DNA structures that are not part of a chromosome.,extrachromosomal circular DNA,cellular_component
60903,GO:0005728,"Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.",extrachromosomal rDNA circle,cellular_component
60904,GO:0005729,"A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies.",2-micrometer circle DNA,cellular_component
60905,GO:0005730,"A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the...",nucleolus,cellular_component
60906,GO:0005731,"A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.",nucleolus organizer region,cellular_component
60907,GO:0005732,"A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.",sno(s)RNA-containing ribonucleoprotein complex,cellular_component
60908,GO:0005736,"RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RN...",RNA polymerase I complex,cellular_component
60909,GO:0005737,"The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",cytoplasm,cellular_component
60910,GO:0005739,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",mitochondrion,cellular_component
60911,GO:0005740,The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.,mitochondrial envelope,cellular_component
60912,GO:0005741,"The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.",mitochondrial outer membrane,cellular_component
60913,GO:0005742,A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.,mitochondrial outer membrane translocase complex,cellular_component
60914,GO:0005743,"The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.",mitochondrial inner membrane,cellular_component
60915,GO:0005744,The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.,TIM23 mitochondrial import inner membrane translocase complex,cellular_component
60916,GO:0005745,Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.,m-AAA complex,cellular_component
60917,GO:0005757,"A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).",mitochondrial permeability transition pore complex,cellular_component
60918,GO:0005758,The region between the inner and outer lipid bilayers of the mitochondrial envelope.,mitochondrial intermembrane space,cellular_component
60919,GO:0005759,"The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",mitochondrial matrix,cellular_component
60920,GO:0005760,"A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.",gamma DNA polymerase complex,cellular_component
60921,GO:0005761,A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.,mitochondrial ribosome,cellular_component
60922,GO:0005762,The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).,mitochondrial large ribosomal subunit,cellular_component
60923,GO:0005763,The smaller of the two subunits of a mitochondrial ribosome.,mitochondrial small ribosomal subunit,cellular_component
60924,GO:0005764,"A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.",lysosome,cellular_component
60925,GO:0005765,The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.,lysosomal membrane,cellular_component
60926,GO:0005766,A lysosome before it has fused with a vesicle or vacuole.,primary lysosome,cellular_component
60927,GO:0005767,Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.,secondary lysosome,cellular_component
60928,GO:0005768,A vacuole to which materials ingested by endocytosis are delivered.,endosome,cellular_component
60929,GO:0005769,A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.,early endosome,cellular_component
60930,GO:0005770,"A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.",late endosome,cellular_component
60931,GO:0005771,A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.,multivesicular body,cellular_component
60932,GO:0005773,"A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.",vacuole,cellular_component
60933,GO:0005774,The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.,vacuolar membrane,cellular_component
60934,GO:0005775,The volume enclosed within the vacuolar membrane.,vacuolar lumen,cellular_component
60935,GO:0005776,A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.,autophagosome,cellular_component
60936,GO:0005777,"A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.",peroxisome,cellular_component
60937,GO:0005778,The lipid bilayer surrounding a peroxisome.,peroxisomal membrane,cellular_component
60938,GO:0005780,"The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of intraperoxisomal membrane,cellular_component
60939,GO:0005782,The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.,peroxisomal matrix,cellular_component
60940,GO:0005783,"The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).",endoplasmic reticulum,cellular_component
60941,GO:0005784,"A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.",Sec61 translocon complex,cellular_component
60942,GO:0005785,"A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.",signal recognition particle receptor complex,cellular_component
60943,GO:0005786,A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is...,"signal recognition particle, endoplasmic reticulum targeting",cellular_component
60944,GO:0005787,A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.,signal peptidase complex,cellular_component
60945,GO:0005788,The volume enclosed by the membranes of the endoplasmic reticulum.,endoplasmic reticulum lumen,cellular_component
60946,GO:0005789,The lipid bilayer surrounding the endoplasmic reticulum.,endoplasmic reticulum membrane,cellular_component
60947,GO:0005790,"The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the pho...",smooth endoplasmic reticulum,cellular_component
60948,GO:0005791,"The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.",rough endoplasmic reticulum,cellular_component
60949,GO:0005793,"A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.",endoplasmic reticulum-Golgi intermediate compartment,cellular_component
60950,GO:0005794,"A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.",Golgi apparatus,cellular_component
60951,GO:0005795,"The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.",Golgi stack,cellular_component
60952,GO:0005796,"The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.",Golgi lumen,cellular_component
60953,GO:0005797,The middle Golgi cisterna (or cisternae).,Golgi medial cisterna,cellular_component
60954,GO:0005798,Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.,Golgi-associated vesicle,cellular_component
60955,GO:0005801,"The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.",cis-Golgi network,cellular_component
60956,GO:0005802,"The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.",trans-Golgi network,cellular_component
60957,GO:0005811,An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.,lipid droplet,cellular_component
60958,GO:0005813,"A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.",centrosome,cellular_component
60959,GO:0005814,"A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole o...",centriole,cellular_component
60960,GO:0005815,"An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.",microtubule organizing center,cellular_component
60961,GO:0005816,The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.,spindle pole body,cellular_component
60962,GO:0005818,An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.,aster,cellular_component
60963,GO:0005819,The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.,spindle,cellular_component
60964,GO:0005821,Structure between the central and outer plaques of the spindle pole body.,intermediate layer of spindle pole body,cellular_component
60965,GO:0005822,One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.,inner plaque of spindle pole body,cellular_component
60966,GO:0005823,One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.,central plaque of spindle pole body,cellular_component
60967,GO:0005824,One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.,outer plaque of spindle pole body,cellular_component
60968,GO:0005825,Structure adjacent to the plaques of the spindle pole body.,half bridge of spindle pole body,cellular_component
60969,GO:0005826,"A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.",actomyosin contractile ring,cellular_component
60970,GO:0005827,Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.,polar microtubule,cellular_component
60971,GO:0005828,"Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.",kinetochore microtubule,cellular_component
60972,GO:0005829,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",cytosol,cellular_component
60973,GO:0005831,"A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.",steroid hormone aporeceptor complex,cellular_component
60974,GO:0005832,A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.,chaperonin-containing T-complex,cellular_component
60975,GO:0005833,"An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.",hemoglobin complex,cellular_component
60976,GO:0005834,Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to trans...,heterotrimeric G-protein complex,cellular_component
60977,GO:0005835,A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.,fatty acid synthase complex,cellular_component
60978,GO:0005836,A protein complex that possesses fatty-acyl-CoA synthase activity.,fatty-acyl-CoA synthase complex,cellular_component
60979,GO:0005838,"A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.",proteasome regulatory particle,cellular_component
60980,GO:0005839,"A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.",proteasome core complex,cellular_component
60981,GO:0005840,"An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, wh...",ribosome,cellular_component
60982,GO:0005846,"A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.",nuclear cap binding complex,cellular_component
60983,GO:0005847,"A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.",mRNA cleavage and polyadenylation specificity factor complex,cellular_component
60984,GO:0005848,A protein complex required for mRNA cleavage but not for poly(A) addition.,mRNA cleavage stimulating factor complex,cellular_component
60985,GO:0005849,Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.,mRNA cleavage factor complex,cellular_component
60986,GO:0005850,"Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.",eukaryotic translation initiation factor 2 complex,cellular_component
60987,GO:0005851,"A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.",eukaryotic translation initiation factor 2B complex,cellular_component
60988,GO:0005852,"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex wit...",eukaryotic translation initiation factor 3 complex,cellular_component
60989,GO:0005853,"A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.",eukaryotic translation elongation factor 1 complex,cellular_component
60990,GO:0005854,"A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.",nascent polypeptide-associated complex,cellular_component
60991,GO:0005856,"A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, end...",cytoskeleton,cellular_component
60992,GO:0005858,A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.,axonemal dynein complex,cellular_component
60993,GO:0005859,A filament of myosin found in a muscle cell of any type.,muscle myosin complex,cellular_component
60994,GO:0005861,"A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.",troponin complex,cellular_component
60995,GO:0005862,A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.,muscle thin filament tropomyosin,cellular_component
60996,GO:0005863,"Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.",striated muscle myosin thick filament,cellular_component
60997,GO:0005865,Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.,striated muscle thin filament,cellular_component
60998,GO:0005868,"Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intr...",cytoplasmic dynein complex,cellular_component
60999,GO:0005869,"A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.",dynactin complex,cellular_component
61000,GO:0005871,"Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin comp...",kinesin complex,cellular_component
61001,GO:0005872,"Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.",minus-end kinesin complex,cellular_component
61002,GO:0005873,"Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule.",plus-end kinesin complex,cellular_component
61003,GO:0005874,"Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapid...",microtubule,cellular_component
61004,GO:0005875,Any multimeric complex connected to a microtubule.,microtubule associated complex,cellular_component
61005,GO:0005876,Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.,spindle microtubule,cellular_component
61006,GO:0005879,"A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.",axonemal microtubule,cellular_component
61007,GO:0005880,Any microtubule in the nucleus of a cell.,nuclear microtubule,cellular_component
61008,GO:0005881,Any microtubule in the cytoplasm of a cell.,cytoplasmic microtubule,cellular_component
61009,GO:0005882,"A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vime...",intermediate filament,cellular_component
61010,GO:0005883,"A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.",neurofilament,cellular_component
61011,GO:0005884,"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the c...",actin filament,cellular_component
61012,GO:0005885,"A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.",Arp2/3 protein complex,cellular_component
61013,GO:0005886,The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.,plasma membrane,cellular_component
61014,GO:0005889,"A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.",potassium:proton exchanging ATPase complex,cellular_component
61015,GO:0005890,"Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.",sodium:potassium-exchanging ATPase complex,cellular_component
61016,GO:0005891,A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.,voltage-gated calcium channel complex,cellular_component
61017,GO:0005892,A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.,acetylcholine-gated channel complex,cellular_component
61018,GO:0005893,"A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.",interleukin-2 receptor complex,cellular_component
61019,GO:0005894,"A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5.",interleukin-3 receptor complex,cellular_component
61020,GO:0005895,"A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3.",interleukin-5 receptor complex,cellular_component
61021,GO:0005896,"A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.",interleukin-6 receptor complex,cellular_component
61022,GO:0005897,"A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.",interleukin-9 receptor complex,cellular_component
61023,GO:0005898,"A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.",interleukin-13 receptor complex,cellular_component
61024,GO:0005899,"A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.",insulin receptor complex,cellular_component
61025,GO:0005900,A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.,type I oncostatin-M receptor complex,cellular_component
61026,GO:0005901,"A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.",caveola,cellular_component
61027,GO:0005902,Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.,microvillus,cellular_component
61028,GO:0005903,"The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.",brush border,cellular_component
61029,GO:0005905,"A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.",clathrin-coated pit,cellular_component
61030,GO:0005911,"A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.",cell-cell junction,cellular_component
61031,GO:0005912,"A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.",adherens junction,cellular_component
61032,GO:0005914,A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.,spot adherens junction,cellular_component
61033,GO:0005915,A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.,zonula adherens,cellular_component
61034,GO:0005916,"A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.",fascia adherens,cellular_component
61035,GO:0005917,"A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.",nephrocyte diaphragm,cellular_component
61036,GO:0005918,A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.,septate junction,cellular_component
61037,GO:0005919,A septate junction in which regular arrays of electron-dense septae span the intermembrane space.,pleated septate junction,cellular_component
61038,GO:0005920,A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.,smooth septate junction,cellular_component
61039,GO:0005921,"A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.",gap junction,cellular_component
61040,GO:0005922,"An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.",connexin complex,cellular_component
61041,GO:0005923,An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.,bicellular tight junction,cellular_component
61042,GO:0005925,A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).,focal adhesion,cellular_component
61043,GO:0005927,A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.,muscle tendon junction,cellular_component
61044,GO:0005929,"A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.",cilium,cellular_component
61045,GO:0005930,The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.,axoneme,cellular_component
61046,GO:0005931,A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules.,axonemal nexin link,cellular_component
61047,GO:0005933,"A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.",cellular bud,cellular_component
61048,GO:0005934,The end of a cellular bud distal to the site of attachment to the mother cell.,cellular bud tip,cellular_component
61049,GO:0005935,The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.,cellular bud neck,cellular_component
61050,GO:0005937,The projection formed by unicellular fungi in response to mating pheromone.,mating projection,cellular_component
61051,GO:0005938,"The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.",cell cortex,cellular_component
61052,GO:0005940,"A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.",septin ring,cellular_component
61053,GO:0005942,"A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adapt...",phosphatidylinositol 3-kinase complex,cellular_component
61054,GO:0005943,"A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.","phosphatidylinositol 3-kinase complex, class IA",cellular_component
61055,GO:0005944,"A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.","phosphatidylinositol 3-kinase complex, class IB",cellular_component
61056,GO:0005945,"A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.",6-phosphofructokinase complex,cellular_component
61057,GO:0005946,"A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.","alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)",cellular_component
61058,GO:0005948,A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.,acetolactate synthase complex,cellular_component
61059,GO:0005950,"A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.",anthranilate synthase complex,cellular_component
61060,GO:0005951,"A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.",carbamoyl-phosphate synthase complex,cellular_component
61061,GO:0005952,"An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.",cAMP-dependent protein kinase complex,cellular_component
61062,GO:0005953,"A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.",CAAX-protein geranylgeranyltransferase complex,cellular_component
61063,GO:0005954,"An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.",calcium- and calmodulin-dependent protein kinase complex,cellular_component
61064,GO:0005955,A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.,calcineurin complex,cellular_component
61065,GO:0005956,"A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.",protein kinase CK2 complex,cellular_component
61066,GO:0005958,"A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.",DNA-dependent protein kinase-DNA ligase 4 complex,cellular_component
61067,GO:0005960,"A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.",glycine cleavage complex,cellular_component
61068,GO:0005963,"An intracellular enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.",magnesium-dependent protein serine/threonine phosphatase complex,cellular_component
61069,GO:0005964,An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a.,phosphorylase kinase complex,cellular_component
61070,GO:0005965,A protein complex that possesses protein farnesyltransferase activity.,protein farnesyltransferase complex,cellular_component
61071,GO:0005968,"An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein).",Rab-protein geranylgeranyltransferase complex,cellular_component
61072,GO:0005969,A protein homodimeric complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.,serine-pyruvate aminotransferase complex,cellular_component
61073,GO:0005971,"An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.",ribonucleoside-diphosphate reductase complex,cellular_component
61074,GO:0005975,"The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate metabolic process,biological_process
61075,GO:0005976,"The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.",polysaccharide metabolic process,biological_process
61076,GO:0005977,"The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.",glycogen metabolic process,biological_process
61077,GO:0005978,"The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.",glycogen biosynthetic process,biological_process
61078,GO:0005979,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.",regulation of glycogen biosynthetic process,biological_process
61079,GO:0005980,"The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.",glycogen catabolic process,biological_process
61080,GO:0005981,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.",regulation of glycogen catabolic process,biological_process
61081,GO:0005982,"The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.",starch metabolic process,biological_process
61082,GO:0005983,"The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.",starch catabolic process,biological_process
61083,GO:0005984,"The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.",disaccharide metabolic process,biological_process
61084,GO:0005985,"The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.",sucrose metabolic process,biological_process
61085,GO:0005986,"The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.",sucrose biosynthetic process,biological_process
61086,GO:0005987,"The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.",sucrose catabolic process,biological_process
61087,GO:0005988,"The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.",lactose metabolic process,biological_process
61088,GO:0005989,"The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.",lactose biosynthetic process,biological_process
61089,GO:0005990,"The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.",lactose catabolic process,biological_process
61090,GO:0005991,"The chemical reactions and pathways involving trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.",trehalose metabolic process,biological_process
61091,GO:0005992,"The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.",trehalose biosynthetic process,biological_process
61092,GO:0005993,"The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.",trehalose catabolic process,biological_process
61093,GO:0005995,"The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.",melibiose catabolic process,biological_process
61094,GO:0005996,"The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.",monosaccharide metabolic process,biological_process
61095,GO:0005997,"The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.",xylulose metabolic process,biological_process
61096,GO:0005998,"The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.",xylulose catabolic process,biological_process
61097,GO:0005999,"The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.",xylulose biosynthetic process,biological_process
61098,GO:0006000,"The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.",fructose metabolic process,biological_process
61099,GO:0006001,"The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.",fructose catabolic process,biological_process
61100,GO:0006002,"The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.",fructose 6-phosphate metabolic process,biological_process
61101,GO:0006003,"The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.","fructose 2,6-bisphosphate metabolic process",biological_process
61102,GO:0006004,"The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.",fucose metabolic process,biological_process
61103,GO:0006005,The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).,L-fucose biosynthetic process,biological_process
61104,GO:0006006,"The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.",glucose metabolic process,biological_process
61105,GO:0006007,"The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.",glucose catabolic process,biological_process
61106,GO:0006009,The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate.,glucose 1-phosphate phosphorylation,biological_process
61107,GO:0006011,"The chemical reactions and pathways involving UDP-alpha-D-glucose, a substance composed of alpha-D-glucose in glycosidic linkage with uridine diphosphate.",UDP-alpha-D-glucose metabolic process,biological_process
61108,GO:0006012,"The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.",galactose metabolic process,biological_process
61109,GO:0006013,"The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.",mannose metabolic process,biological_process
61110,GO:0006014,"The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.",D-ribose metabolic process,biological_process
61111,GO:0006015,"The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.",5-phosphoribose 1-diphosphate biosynthetic process,biological_process
61112,GO:0006016,"The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.",2-deoxyribose 1-phosphate biosynthetic process,biological_process
61113,GO:0006018,"The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.",2-deoxyribose 1-phosphate catabolic process,biological_process
61114,GO:0006020,"The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.",inositol metabolic process,biological_process
61115,GO:0006021,"The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.",inositol biosynthetic process,biological_process
61116,GO:0006022,"The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.",aminoglycan metabolic process,biological_process
61117,GO:0006023,"The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.",aminoglycan biosynthetic process,biological_process
61118,GO:0006024,"The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units.",glycosaminoglycan biosynthetic process,biological_process
61119,GO:0006026,"The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.",aminoglycan catabolic process,biological_process
61120,GO:0006027,"The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units.",glycosaminoglycan catabolic process,biological_process
61121,GO:0006029,"The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",proteoglycan metabolic process,biological_process
61122,GO:0006030,"The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.",chitin metabolic process,biological_process
61123,GO:0006031,"The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.",chitin biosynthetic process,biological_process
61124,GO:0006032,"The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.",chitin catabolic process,biological_process
61125,GO:0006033,"A process in which chitin is transported to, or maintained in, a specific location.",chitin localization,biological_process
61126,GO:0006040,"The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.",amino sugar metabolic process,biological_process
61127,GO:0006041,"The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.",D-glucosamine metabolic process,biological_process
61128,GO:0006042,"The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.",D-glucosamine biosynthetic process,biological_process
61129,GO:0006043,"The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.",D-glucosamine catabolic process,biological_process
61130,GO:0006044,"The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.",N-acetylglucosamine metabolic process,biological_process
61131,GO:0006045,"The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.",N-acetylglucosamine biosynthetic process,biological_process
61132,GO:0006046,"The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.",N-acetylglucosamine catabolic process,biological_process
61133,GO:0006047,"The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylglucosamine metabolic process,biological_process
61134,GO:0006048,"The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylglucosamine biosynthetic process,biological_process
61135,GO:0006051,"The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.",N-acetylmannosamine metabolic process,biological_process
61136,GO:0006052,"The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.",N-acetylmannosamine biosynthetic process,biological_process
61137,GO:0006053,"The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.",N-acetylmannosamine catabolic process,biological_process
61138,GO:0006054,"The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.",N-acetylneuraminate metabolic process,biological_process
61139,GO:0006055,"The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.",CMP-N-acetylneuraminate biosynthetic process,biological_process
61140,GO:0006059,"The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule.",hexitol metabolic process,biological_process
61141,GO:0006060,"The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.",D-sorbitol metabolic process,biological_process
61142,GO:0006061,"The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.",D-sorbitol biosynthetic process,biological_process
61143,GO:0006062,"The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.",D-sorbitol catabolic process,biological_process
61144,GO:0006064,"The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.",glucuronate catabolic process,biological_process
61145,GO:0006065,"The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.",UDP-glucuronate biosynthetic process,biological_process
61146,GO:0006066,"The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.",alcohol metabolic process,biological_process
61147,GO:0006067,"The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.",ethanol metabolic process,biological_process
61148,GO:0006068,"The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.",ethanol catabolic process,biological_process
61149,GO:0006070,"The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.",octanol metabolic process,biological_process
61150,GO:0006071,"The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.",glycerol metabolic process,biological_process
61151,GO:0006072,"The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.",glycerol-3-phosphate metabolic process,biological_process
61152,GO:0006074,"The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.",(1->3)-beta-D-glucan metabolic process,biological_process
61153,GO:0006075,"The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.",(1->3)-beta-D-glucan biosynthetic process,biological_process
61154,GO:0006076,The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.,(1->3)-beta-D-glucan catabolic process,biological_process
61155,GO:0006077,"The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.",(1->6)-beta-D-glucan metabolic process,biological_process
61156,GO:0006078,The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.,(1->6)-beta-D-glucan biosynthetic process,biological_process
61157,GO:0006079,The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.,(1->6)-beta-D-glucan catabolic process,biological_process
61158,GO:0006080,"The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.",substituted mannan metabolic process,biological_process
61159,GO:0006081,"The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.",aldehyde metabolic process,biological_process
61160,GO:0006083,"The chemical reactions and pathways involving acetate, the anion of acetic acid.",acetate metabolic process,biological_process
61161,GO:0006084,"The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.",acetyl-CoA metabolic process,biological_process
61162,GO:0006085,"The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.",acetyl-CoA biosynthetic process,biological_process
61163,GO:0006086,"The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.  In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: pyruvate + coenzyme A + NAD+ -> acetyl-CoA + CO2 + NADH.",pyruvate decarboxylation to acetyl-CoA,biological_process
61164,GO:0006089,"The chemical reactions and pathways involving lactate, the anion of lactic acid.",lactate metabolic process,biological_process
61165,GO:0006090,"The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.",pyruvate metabolic process,biological_process
61166,GO:0006091,"The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.",generation of precursor metabolites and energy,biological_process
61167,GO:0006094,"The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.",gluconeogenesis,biological_process
61168,GO:0006096,"The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.",glycolytic process,biological_process
61169,GO:0006097,"A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.",glyoxylate cycle,biological_process
61170,GO:0006098,"The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).",pentose-phosphate shunt,biological_process
61171,GO:0006099,"A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate c...",tricarboxylic acid cycle,biological_process
61172,GO:0006101,"The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboxylate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.",citrate metabolic process,biological_process
61173,GO:0006102,"The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.",isocitrate metabolic process,biological_process
61174,GO:0006103,"The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.",2-oxoglutarate metabolic process,biological_process
61175,GO:0006104,"The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.",succinyl-CoA metabolic process,biological_process
61176,GO:0006105,"The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.",succinate metabolic process,biological_process
61177,GO:0006106,"The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.",fumarate metabolic process,biological_process
61178,GO:0006107,"The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.",oxaloacetate metabolic process,biological_process
61179,GO:0006108,"The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.",malate metabolic process,biological_process
61180,GO:0006109,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.",regulation of carbohydrate metabolic process,biological_process
61181,GO:0006110,"Any process that modulates the frequency, rate or extent of glycolysis.",regulation of glycolytic process,biological_process
61182,GO:0006111,"Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.",regulation of gluconeogenesis,biological_process
61183,GO:0006112,The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.,energy reserve metabolic process,biological_process
61184,GO:0006113,"The metabolic process that uses oxidation-reduction reactions of organic compounds and substrate-level phosphorylation for the generation of adenosine triphosphate (ATP), without consuming oxygen and is independent of electron transport chains.",fermentation,biological_process
61185,GO:0006114,"The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.",glycerol biosynthetic process,biological_process
61186,GO:0006115,"The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.",ethanol biosynthetic process,biological_process
61187,GO:0006117,"The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.",acetaldehyde metabolic process,biological_process
61188,GO:0006119,"The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.",oxidative phosphorylation,biological_process
61189,GO:0006120,The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.,"mitochondrial electron transport, NADH to ubiquinone",biological_process
61190,GO:0006121,"The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.","mitochondrial electron transport, succinate to ubiquinone",biological_process
61191,GO:0006122,"The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.","mitochondrial electron transport, ubiquinol to cytochrome c",biological_process
61192,GO:0006123,"The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.","mitochondrial electron transport, cytochrome c to oxygen",biological_process
61193,GO:0006124,"The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.",ferredoxin metabolic process,biological_process
61194,GO:0006127,"The process of transferring reducing equivalents from NADH in the cytosol into the mitochondria via glycerol-3-phosphate. Cytosolic glycerol-3-phosphate dehydrogenase uses NADH to convert dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate (G3P) in the cytosol; G3P then diffuses into the mitochondria where mitochondrial glycerol-3-phosphate dehydrogenase uses FAD to convert G3P back to DHAP; the electrons on the reduced FADH2 are then available for use in the electron transport chain, a...",glycerol-3-phosphate shuttle,biological_process
61195,GO:0006139,"Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.",nucleobase-containing compound metabolic process,biological_process
61196,GO:0006140,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.",regulation of nucleotide metabolic process,biological_process
61197,GO:0006141,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.",regulation of purine nucleobase metabolic process,biological_process
61198,GO:0006144,"The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.",purine nucleobase metabolic process,biological_process
61199,GO:0006145,"The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.",purine nucleobase catabolic process,biological_process
61200,GO:0006146,"The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.",adenine catabolic process,biological_process
61201,GO:0006147,"The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.",guanine catabolic process,biological_process
61202,GO:0006148,"The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.",inosine catabolic process,biological_process
61203,GO:0006149,"The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.",deoxyinosine catabolic process,biological_process
61204,GO:0006152,"The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).",purine nucleoside catabolic process,biological_process
61205,GO:0006154,"The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.",adenosine catabolic process,biological_process
61206,GO:0006157,"The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.",deoxyadenosine catabolic process,biological_process
61207,GO:0006161,"The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.",deoxyguanosine catabolic process,biological_process
61208,GO:0006163,"The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine nucleotide metabolic process,biological_process
61209,GO:0006164,"The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine nucleotide biosynthetic process,biological_process
61210,GO:0006166,"Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.",purine ribonucleoside salvage,biological_process
61211,GO:0006167,"The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.",AMP biosynthetic process,biological_process
61212,GO:0006168,"Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.",adenine salvage,biological_process
61213,GO:0006169,"Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.",adenosine salvage,biological_process
61214,GO:0006170,"The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).",dAMP biosynthetic process,biological_process
61215,GO:0006171,"The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).",cAMP biosynthetic process,biological_process
61216,GO:0006172,"The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.",ADP biosynthetic process,biological_process
61217,GO:0006173,"The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).",dADP biosynthetic process,biological_process
61218,GO:0006175,"The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).",dATP biosynthetic process,biological_process
61219,GO:0006177,"The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.",GMP biosynthetic process,biological_process
61220,GO:0006178,"Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.",guanine salvage,biological_process
61221,GO:0006179,"Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.",guanosine salvage,biological_process
61222,GO:0006180,"Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis.",deoxyguanosine salvage,biological_process
61223,GO:0006181,"The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).",dGMP biosynthetic process,biological_process
61224,GO:0006182,"The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.",cGMP biosynthetic process,biological_process
61225,GO:0006183,"The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.",GTP biosynthetic process,biological_process
61226,GO:0006185,"The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).",dGDP biosynthetic process,biological_process
61227,GO:0006188,"The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.",IMP biosynthetic process,biological_process
61228,GO:0006189,"The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.",'de novo' IMP biosynthetic process,biological_process
61229,GO:0006190,"Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis.",inosine salvage,biological_process
61230,GO:0006191,"Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.",deoxyinosine salvage,biological_process
61231,GO:0006193,"The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.",ITP catabolic process,biological_process
61232,GO:0006195,"The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine nucleotide catabolic process,biological_process
61233,GO:0006196,"The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.",AMP catabolic process,biological_process
61234,GO:0006198,"The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).",cAMP catabolic process,biological_process
61235,GO:0006203,"The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.",dGTP catabolic process,biological_process
61236,GO:0006204,"The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.",IMP catabolic process,biological_process
61237,GO:0006206,"The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.",pyrimidine nucleobase metabolic process,biological_process
61238,GO:0006207,"The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.",'de novo' pyrimidine nucleobase biosynthetic process,biological_process
61239,GO:0006208,"The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.",pyrimidine nucleobase catabolic process,biological_process
61240,GO:0006209,"The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.",cytosine catabolic process,biological_process
61241,GO:0006210,"The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.",thymine catabolic process,biological_process
61242,GO:0006212,"The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.",uracil catabolic process,biological_process
61243,GO:0006213,"The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).",pyrimidine nucleoside metabolic process,biological_process
61244,GO:0006214,"The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.",thymidine catabolic process,biological_process
61245,GO:0006216,"The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.",cytidine catabolic process,biological_process
61246,GO:0006217,"The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.",deoxycytidine catabolic process,biological_process
61247,GO:0006218,"The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.",uridine catabolic process,biological_process
61248,GO:0006219,"The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.",deoxyuridine catabolic process,biological_process
61249,GO:0006220,"The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine nucleotide metabolic process,biological_process
61250,GO:0006221,"The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine nucleotide biosynthetic process,biological_process
61251,GO:0006222,"The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.",UMP biosynthetic process,biological_process
61252,GO:0006223,"Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.",uracil salvage,biological_process
61253,GO:0006225,"The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.",UDP biosynthetic process,biological_process
61254,GO:0006226,"The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).",dUMP biosynthetic process,biological_process
61255,GO:0006227,"The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).",dUDP biosynthetic process,biological_process
61256,GO:0006228,"The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.",UTP biosynthetic process,biological_process
61257,GO:0006229,"The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.",dUTP biosynthetic process,biological_process
61258,GO:0006230,"The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.",TMP biosynthetic process,biological_process
61259,GO:0006231,"The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).",dTMP biosynthetic process,biological_process
61260,GO:0006232,"The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.",TDP biosynthetic process,biological_process
61261,GO:0006233,"The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).",dTDP biosynthetic process,biological_process
61262,GO:0006234,"The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate.",TTP biosynthetic process,biological_process
61263,GO:0006235,"The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.",dTTP biosynthetic process,biological_process
61264,GO:0006237,"Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis.",deoxycytidine salvage,biological_process
61265,GO:0006238,"Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.",CMP salvage,biological_process
61266,GO:0006239,"Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis.",dCMP salvage,biological_process
61267,GO:0006240,"The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.",dCDP biosynthetic process,biological_process
61268,GO:0006241,"The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.",CTP biosynthetic process,biological_process
61269,GO:0006242,"The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.",dCTP biosynthetic process,biological_process
61270,GO:0006244,"The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine nucleotide catabolic process,biological_process
61271,GO:0006245,"The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.",TDP catabolic process,biological_process
61272,GO:0006246,"The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate.",dTDP catabolic process,biological_process
61273,GO:0006248,"The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate.",CMP catabolic process,biological_process
61274,GO:0006249,"The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.",dCMP catabolic process,biological_process
61275,GO:0006251,"The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate.",dCDP catabolic process,biological_process
61276,GO:0006253,"The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.",dCTP catabolic process,biological_process
61277,GO:0006254,"The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.",CTP catabolic process,biological_process
61278,GO:0006256,"The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.",UDP catabolic process,biological_process
61279,GO:0006257,"The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.",dUDP catabolic process,biological_process
61280,GO:0006259,"Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.",DNA metabolic process,biological_process
61281,GO:0006260,"The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA m...",DNA replication,biological_process
61282,GO:0006261,A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.,DNA-templated DNA replication,biological_process
61283,GO:0006264,The process in which new strands of DNA are synthesized in the mitochondrion.,mitochondrial DNA replication,biological_process
61284,GO:0006265,"The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.",DNA topological change,biological_process
61285,GO:0006267,"The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.",pre-replicative complex assembly involved in nuclear cell cycle DNA replication,biological_process
61286,GO:0006269,"The synthesis of a short nucleotide polymer using one strand of unwound DNA as a template. The product is usually a RNA molecule between 4-15 nucleotides long that provides a free 3'-OH that can be extended by DNA-directed DNA polymerases. In certain conditions, for example in response to DNA damage, some primases synthesize a DNA primer.","DNA replication, synthesis of primer",biological_process
61287,GO:0006270,"The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.",DNA replication initiation,biological_process
61288,GO:0006271,"The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication.",DNA strand elongation involved in DNA replication,biological_process
61289,GO:0006272,"The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork.",leading strand elongation,biological_process
61290,GO:0006273,"The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, ...",lagging strand elongation,biological_process
61291,GO:0006274,The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.,DNA replication termination,biological_process
61292,GO:0006275,"Any process that modulates the frequency, rate or extent of DNA replication.",regulation of DNA replication,biological_process
61293,GO:0006276,The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.,plasmid maintenance,biological_process
61294,GO:0006277,The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.,DNA amplification,biological_process
61295,GO:0006278,A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.,RNA-templated DNA biosynthetic process,biological_process
61296,GO:0006279,The replication of DNA that precedes meiotic cell division.,premeiotic DNA replication,biological_process
61297,GO:0006281,"The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, p...",DNA repair,biological_process
61298,GO:0006282,"Any process that modulates the frequency, rate or extent of DNA repair.",regulation of DNA repair,biological_process
61299,GO:0006283,"The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.",transcription-coupled nucleotide-excision repair,biological_process
61300,GO:0006284,"In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.",base-excision repair,biological_process
61301,GO:0006285,"The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.","base-excision repair, AP site formation",biological_process
61302,GO:0006287,"Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.","base-excision repair, gap-filling",biological_process
61303,GO:0006289,"A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).",nucleotide-excision repair,biological_process
61304,GO:0006290,"The repair of UV-induced T-T, C-T and C-C dimers.",pyrimidine dimer repair,biological_process
61305,GO:0006293,"The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.","nucleotide-excision repair, preincision complex stabilization",biological_process
61306,GO:0006294,"The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.","nucleotide-excision repair, preincision complex assembly",biological_process
61307,GO:0006297,Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.,"nucleotide-excision repair, DNA gap filling",biological_process
61308,GO:0006298,"A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.",mismatch repair,biological_process
61309,GO:0006301,"A process that promotes the bypass of single-stranded DNA lesions encountered by DNA polymerases during DNA replication, thereby preventing replication fork stalling and allowing completion of DNA replication without removing the damage.",DNA damage tolerance,biological_process
61310,GO:0006302,The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.,double-strand break repair,biological_process
61311,GO:0006303,"The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.",double-strand break repair via nonhomologous end joining,biological_process
61312,GO:0006304,"The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.",DNA modification,biological_process
61313,GO:0006307,"The repair of alkylation damage in DNA, e.g. the removal of a non-physiological alkyl group from a nucleobase. This is usually mediated by DNA alkyltransferases.",DNA alkylation repair,biological_process
61314,GO:0006308,"The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.",DNA catabolic process,biological_process
61315,GO:0006309,"The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.",apoptotic DNA fragmentation,biological_process
61316,GO:0006310,"Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.",DNA recombination,biological_process
61317,GO:0006311,"The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of th...",meiotic gene conversion,biological_process
61318,GO:0006312,"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.",mitotic recombination,biological_process
61319,GO:0006313,"A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.",DNA transposition,biological_process
61320,GO:0006314,"Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.",intron homing,biological_process
61321,GO:0006315,"Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.",homing of group II introns,biological_process
61322,GO:0006316,"Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.",movement of group I intron,biological_process
61323,GO:0006325,"The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.",chromatin organization,biological_process
61324,GO:0006334,"The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",nucleosome assembly,biological_process
61325,GO:0006335,"The formation of nucleosomes on newly synthesized DNA, coupled to strand elongation.",DNA replication-dependent chromatin assembly,biological_process
61326,GO:0006337,"The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",nucleosome disassembly,biological_process
61327,GO:0006338,"A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.",chromatin remodeling,biological_process
61328,GO:0006346,Formation of constitutive heterochromatin by a pathway that includes methylation of genomic DNA such as CpG islands.,DNA methylation-dependent constitutive heterochromatin formation,biological_process
61329,GO:0006351,The synthesis of an RNA transcript from a DNA template.,DNA-templated transcription,biological_process
61330,GO:0006352,"The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.",DNA-templated transcription initiation,biological_process
61331,GO:0006353,"The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.",DNA-templated transcription termination,biological_process
61332,GO:0006354,The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.,DNA-templated transcription elongation,biological_process
61333,GO:0006355,"Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",regulation of DNA-templated transcription,biological_process
61334,GO:0006356,"Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I.",regulation of transcription by RNA polymerase I,biological_process
61335,GO:0006357,"Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.",regulation of transcription by RNA polymerase II,biological_process
61336,GO:0006359,"Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.",regulation of transcription by RNA polymerase III,biological_process
61337,GO:0006360,"The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.",transcription by RNA polymerase I,biological_process
61338,GO:0006361,A transcription initiation process that takes place at a RNA polymerase I gene promoter. Ribosomal RNAs (rRNA) genes are transcribed by RNA polymerase I.,transcription initiation at RNA polymerase I promoter,biological_process
61339,GO:0006362,The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.,transcription elongation by RNA polymerase I,biological_process
61340,GO:0006363,A transcription termination process that completes the production of a ribosomal RNA transcript. RNAP I termination requires binding of a terminator protein to specific sequences downstream of the transcription unit.,termination of RNA polymerase I transcription,biological_process
61341,GO:0006364,Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.,rRNA processing,biological_process
61342,GO:0006366,"The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).",transcription by RNA polymerase II,biological_process
61343,GO:0006367,"A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II.",transcription initiation at RNA polymerase II promoter,biological_process
61344,GO:0006368,The extension of an RNA molecule after transcription pausing and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.,transcription elongation by RNA polymerase II,biological_process
61345,GO:0006369,A transcription termination process that completes the production of a primary RNA polymerase II transcript.,termination of RNA polymerase II transcription,biological_process
61346,GO:0006370,"The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.",7-methylguanosine mRNA capping,biological_process
61347,GO:0006376,Selection of a splice site by components of the assembling spliceosome.,mRNA splice site recognition,biological_process
61348,GO:0006382,The conversion of an adenosine residue to inosine in an RNA molecule by deamination.,adenosine to inosine editing,biological_process
61349,GO:0006383,"The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.",transcription by RNA polymerase III,biological_process
61350,GO:0006384,"A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III.",transcription initiation at RNA polymerase III promoter,biological_process
61351,GO:0006385,The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.,transcription elongation by RNA polymerase III,biological_process
61352,GO:0006386,A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues.,termination of RNA polymerase III transcription,biological_process
61353,GO:0006388,"Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.","tRNA splicing, via endonucleolytic cleavage and ligation",biological_process
61354,GO:0006390,"The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.",mitochondrial transcription,biological_process
61355,GO:0006391,A transcription initiation process that takes place at a promoter on the mitochondrial chromosome.,transcription initiation at mitochondrial promoter,biological_process
61356,GO:0006392,The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.,transcription elongation by mitochondrial RNA polymerase,biological_process
61357,GO:0006393,A transcription termination process that completes the production of a primary mitochondrial transcript.,termination of mitochondrial transcription,biological_process
61358,GO:0006396,Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.,RNA processing,biological_process
61359,GO:0006397,Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.,mRNA processing,biological_process
61360,GO:0006398,"Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.",mRNA 3'-end processing by stem-loop binding and cleavage,biological_process
61361,GO:0006399,"The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.",tRNA metabolic process,biological_process
61362,GO:0006400,The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.,tRNA modification,biological_process
61363,GO:0006401,"The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.",RNA catabolic process,biological_process
61364,GO:0006402,"The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.",mRNA catabolic process,biological_process
61365,GO:0006403,"A process in which RNA is transported to, or maintained in, a specific location.",RNA localization,biological_process
61366,GO:0006404,The import of RNA from the cytoplasm to the nucleus.,RNA import into nucleus,biological_process
61367,GO:0006405,The directed movement of RNA from the nucleus to the cytoplasm.,RNA export from nucleus,biological_process
61368,GO:0006406,The directed movement of mRNA from the nucleus to the cytoplasm.,mRNA export from nucleus,biological_process
61369,GO:0006408,The directed movement of snRNA from the nucleus to the cytoplasm.,snRNA export from nucleus,biological_process
61370,GO:0006409,The directed movement of tRNA from the nucleus to the cytoplasm.,tRNA export from nucleus,biological_process
61371,GO:0006412,"The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide ch...",translation,biological_process
61372,GO:0006413,"The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.",translational initiation,biological_process
61373,GO:0006414,The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.,translational elongation,biological_process
61374,GO:0006415,"The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).",translational termination,biological_process
61375,GO:0006417,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.",regulation of translation,biological_process
61376,GO:0006418,"The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.",tRNA aminoacylation for protein translation,biological_process
61377,GO:0006419,"The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.",alanyl-tRNA aminoacylation,biological_process
61378,GO:0006420,"The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",arginyl-tRNA aminoacylation,biological_process
61379,GO:0006421,"The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.",asparaginyl-tRNA aminoacylation,biological_process
61380,GO:0006422,"The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA.",aspartyl-tRNA aminoacylation,biological_process
61381,GO:0006423,"The process of coupling L-cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",cysteinyl-tRNA aminoacylation,biological_process
61382,GO:0006424,"The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",glutamyl-tRNA aminoacylation,biological_process
61383,GO:0006425,"The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",glutaminyl-tRNA aminoacylation,biological_process
61384,GO:0006426,"The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.",glycyl-tRNA aminoacylation,biological_process
61385,GO:0006427,"The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.",histidyl-tRNA aminoacylation,biological_process
61386,GO:0006428,"The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",isoleucyl-tRNA aminoacylation,biological_process
61387,GO:0006429,"The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",leucyl-tRNA aminoacylation,biological_process
61388,GO:0006430,"The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.",lysyl-tRNA aminoacylation,biological_process
61389,GO:0006431,"The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",methionyl-tRNA aminoacylation,biological_process
61390,GO:0006432,"The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",phenylalanyl-tRNA aminoacylation,biological_process
61391,GO:0006433,"The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA.",prolyl-tRNA aminoacylation,biological_process
61392,GO:0006434,"The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.",seryl-tRNA aminoacylation,biological_process
61393,GO:0006435,"The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.",threonyl-tRNA aminoacylation,biological_process
61394,GO:0006436,"The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",tryptophanyl-tRNA aminoacylation,biological_process
61395,GO:0006437,"The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",tyrosyl-tRNA aminoacylation,biological_process
61396,GO:0006438,"The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.",valyl-tRNA aminoacylation,biological_process
61397,GO:0006446,"Any process that modulates the frequency, rate or extent of translational initiation.",regulation of translational initiation,biological_process
61398,GO:0006447,"Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron.",regulation of translational initiation by iron,biological_process
61399,GO:0006448,"Any process that modulates the frequency, rate, extent or accuracy of translational elongation.",regulation of translational elongation,biological_process
61400,GO:0006449,"Any process that modulates the frequency, rate or extent of translational termination.",regulation of translational termination,biological_process
61401,GO:0006450,Any process that modulates the ability of the translational apparatus to interpret the genetic code.,regulation of translational fidelity,biological_process
61402,GO:0006451,"The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.",translational readthrough,biological_process
61403,GO:0006452,"A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.",translational frameshifting,biological_process
61404,GO:0006457,The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.,protein folding,biological_process
61405,GO:0006458,The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.,'de novo' protein folding,biological_process
61406,GO:0006463,"The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor.",steroid hormone receptor complex assembly,biological_process
61407,GO:0006468,The process of introducing a phosphate group on to a protein.,protein phosphorylation,biological_process
61408,GO:0006469,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.",negative regulation of protein kinase activity,biological_process
61409,GO:0006470,The process of removing one or more phosphoric residues from a protein.,protein dephosphorylation,biological_process
61410,GO:0006473,"The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",protein acetylation,biological_process
61411,GO:0006474,The acetylation of the N-terminal amino acid of proteins.,N-terminal protein amino acid acetylation,biological_process
61412,GO:0006475,The addition of an acetyl group to a non-terminal amino acid in a protein.,internal protein amino acid acetylation,biological_process
61413,GO:0006476,"The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",protein deacetylation,biological_process
61414,GO:0006477,The addition of a sulfate group as an ester to a protein amino acid.,protein sulfation,biological_process
61415,GO:0006478,The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.,peptidyl-tyrosine sulfation,biological_process
61416,GO:0006479,The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.,protein methylation,biological_process
61417,GO:0006480,The methylation of the N-terminal amino acid of a protein.,N-terminal protein amino acid methylation,biological_process
61418,GO:0006481,The methylation of the C-terminal amino acid of a protein.,C-terminal protein methylation,biological_process
61419,GO:0006482,"The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.",protein demethylation,biological_process
61420,GO:0006487,A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of an asparagine residue.,protein N-linked glycosylation,biological_process
61421,GO:0006488,"The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.",dolichol-linked oligosaccharide biosynthetic process,biological_process
61422,GO:0006489,"The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.",dolichyl diphosphate biosynthetic process,biological_process
61423,GO:0006491,"The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.",N-glycan processing,biological_process
61424,GO:0006493,"A glycoprotein biosynthetic process starting with the covalent linkage of carbohydrate or carbohydrate derivative unit via a glycosidic bond to the oxygen atom of a serine, threonine, hydroxylysine, hydroxyproline or tyrosine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation,biological_process
61425,GO:0006497,The covalent attachment of lipid groups to an amino acid in a protein.,protein lipidation,biological_process
61426,GO:0006498,The covalent attachment of a lipid group to the amino terminus of a protein.,N-terminal protein lipidation,biological_process
61427,GO:0006499,The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.,N-terminal protein myristoylation,biological_process
61428,GO:0006500,The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.,N-terminal protein palmitoylation,biological_process
61429,GO:0006501,The covalent attachment of a lipid group to the carboxy-terminus of a protein.,C-terminal protein lipidation,biological_process
61430,GO:0006505,"The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein ch...",GPI anchor metabolic process,biological_process
61431,GO:0006506,"The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this c...",GPI anchor biosynthetic process,biological_process
61432,GO:0006508,The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.,proteolysis,biological_process
61433,GO:0006509,The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).,membrane protein ectodomain proteolysis,biological_process
61434,GO:0006511,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.",ubiquitin-dependent protein catabolic process,biological_process
61435,GO:0006513,Addition of a single ubiquitin group to a protein.,protein monoubiquitination,biological_process
61436,GO:0006515,The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.,protein quality control for misfolded or incompletely synthesized proteins,biological_process
61437,GO:0006516,"The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",glycoprotein catabolic process,biological_process
61438,GO:0006517,The removal of sugar residues from a glycosylated protein.,protein deglycosylation,biological_process
61439,GO:0006518,"The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.",peptide metabolic process,biological_process
61440,GO:0006520,"The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups.",amino acid metabolic process,biological_process
61441,GO:0006521,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.",regulation of amino acid metabolic process,biological_process
61442,GO:0006523,"The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.",alanine biosynthetic process,biological_process
61443,GO:0006525,"The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.",arginine metabolic process,biological_process
61444,GO:0006526,"The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.",L-arginine biosynthetic process,biological_process
61445,GO:0006527,The chemical reactions and pathways resulting in the breakdown of L-arginine.,L-arginine catabolic process,biological_process
61446,GO:0006530,The chemical reactions and pathways resulting in the breakdown of L-asparagine.,L-asparagine catabolic process,biological_process
61447,GO:0006531,"The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.",aspartate metabolic process,biological_process
61448,GO:0006532,"The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.",L-aspartate biosynthetic process,biological_process
61449,GO:0006533,The chemical reactions and pathways resulting in the breakdown of L-aspartate.,L-aspartate catabolic process,biological_process
61450,GO:0006536,"The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.",glutamate metabolic process,biological_process
61451,GO:0006538,The chemical reactions and pathways resulting in the breakdown of L-glutamate.,L-glutamate catabolic process,biological_process
61452,GO:0006540,"The chemical reactions and pathways resulting in the formation of succinate from L-glutamate via gamma-aminobutyrate (GABA), bypassing two steps of the TCA cycle. It operates through the sequential conversion of glutamate to GABA by glutamate decarboxylase, transamination of GABA to succinic semialdehyde by GABA transaminase, and oxidation of succinic semialdehyde to succinate by succinate semialdehyde dehydrogenase.",GABA shunt,biological_process
61453,GO:0006541,"The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.",L-glutamine metabolic process,biological_process
61454,GO:0006543,The chemical reactions and pathways resulting in the breakdown of L-glutamine.,L-glutamine catabolic process,biological_process
61455,GO:0006544,"The chemical reactions and pathways involving glycine, aminoethanoic acid.",glycine metabolic process,biological_process
61456,GO:0006545,"The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.",glycine biosynthetic process,biological_process
61457,GO:0006546,The chemical reactions and pathways resulting in the breakdown of glycine.,glycine catabolic process,biological_process
61458,GO:0006548,The chemical reactions and pathways resulting in the breakdown of L-histidine.,L-histidine catabolic process,biological_process
61459,GO:0006550,The chemical reactions and pathways resulting in the breakdown of L-isoleucine.,L-isoleucine catabolic process,biological_process
61460,GO:0006551,"The chemical reactions and pathways involving L-leucine, 2-amino-4-methylpentanoic acid.",L-leucine metabolic process,biological_process
61461,GO:0006552,The chemical reactions and pathways resulting in the breakdown of L-leucine.,L-leucine catabolic process,biological_process
61462,GO:0006555,"The chemical reactions and pathways involving L-methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.",L-methionine metabolic process,biological_process
61463,GO:0006556,"The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.",S-adenosylmethionine biosynthetic process,biological_process
61464,GO:0006559,The chemical reactions and pathways resulting in the breakdown of L-phenylalanine.,L-phenylalanine catabolic process,biological_process
61465,GO:0006560,"The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.",L-proline metabolic process,biological_process
61466,GO:0006562,The chemical reactions and pathways resulting in the breakdown of L-proline.,L-proline catabolic process,biological_process
61467,GO:0006563,"The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.",L-serine metabolic process,biological_process
61468,GO:0006564,The chemical reactions and pathways resulting in the formation of L-serine.,L-serine biosynthetic process,biological_process
61469,GO:0006565,The chemical reactions and pathways resulting in the breakdown of L-serine.,L-serine catabolic process,biological_process
61470,GO:0006566,"The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.",L-threonine metabolic process,biological_process
61471,GO:0006567,The chemical reactions and pathways resulting in the breakdown of L-threonine.,L-threonine catabolic process,biological_process
61472,GO:0006569,The chemical reactions and pathways resulting in the breakdown of L-tryptophan.,L-tryptophan catabolic process,biological_process
61473,GO:0006571,"The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.",L-tyrosine biosynthetic process,biological_process
61474,GO:0006572,The chemical reactions and pathways resulting in the breakdown of L-tyrosine.,L-tyrosine catabolic process,biological_process
61475,GO:0006574,The chemical reactions and pathways resulting in the breakdown of L-valine.,L-valine catabolic process,biological_process
61476,GO:0006575,"The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.",modified amino acid metabolic process,biological_process
61477,GO:0006576,"The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.",biogenic amine metabolic process,biological_process
61478,GO:0006577,"The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.",amino-acid betaine metabolic process,biological_process
61479,GO:0006578,"The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.",amino-acid betaine biosynthetic process,biological_process
61480,GO:0006579,"The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.",amino-acid betaine catabolic process,biological_process
61481,GO:0006580,"The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).",ethanolamine metabolic process,biological_process
61482,GO:0006581,"The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.",acetylcholine catabolic process,biological_process
61483,GO:0006582,"The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.",melanin metabolic process,biological_process
61484,GO:0006583,"The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.",melanin biosynthetic process from tyrosine,biological_process
61485,GO:0006584,"The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.",catecholamine metabolic process,biological_process
61486,GO:0006585,"The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.",dopamine biosynthetic process from tyrosine,biological_process
61487,GO:0006589,"The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.",octopamine biosynthetic process,biological_process
61488,GO:0006590,"The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.",thyroid hormone generation,biological_process
61489,GO:0006591,"The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.",ornithine metabolic process,biological_process
61490,GO:0006592,"The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.",L-ornithine biosynthetic process,biological_process
61491,GO:0006593,The chemical reactions and pathways resulting in the breakdown of L-ornithine.,L-ornithine catabolic process,biological_process
61492,GO:0006595,"The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.",polyamine metabolic process,biological_process
61493,GO:0006596,"The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.",polyamine biosynthetic process,biological_process
61494,GO:0006597,"The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.",spermine biosynthetic process,biological_process
61495,GO:0006598,"The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.",polyamine catabolic process,biological_process
61496,GO:0006600,"The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.",creatine metabolic process,biological_process
61497,GO:0006601,"The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, m...",creatine biosynthetic process,biological_process
61498,GO:0006602,"The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.",creatinine catabolic process,biological_process
61499,GO:0006603,"The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.",phosphocreatine metabolic process,biological_process
61500,GO:0006605,"The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.",protein targeting,biological_process
61501,GO:0006606,The directed movement of a protein from the cytoplasm to the nucleus.,protein import into nucleus,biological_process
61502,GO:0006607,"The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope.",NLS-bearing protein import into nucleus,biological_process
61503,GO:0006610,"The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus.",ribosomal protein import into nucleus,biological_process
61504,GO:0006611,The directed movement of a protein from the nucleus into the cytoplasm.,protein export from nucleus,biological_process
61505,GO:0006612,"The process of directing proteins towards a membrane, usually using signals contained within the protein.",protein targeting to membrane,biological_process
61506,GO:0006613,"The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.",cotranslational protein targeting to membrane,biological_process
61507,GO:0006614,"The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.",SRP-dependent cotranslational protein targeting to membrane,biological_process
61508,GO:0006615,"The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.","SRP-dependent cotranslational protein targeting to membrane, docking",biological_process
61509,GO:0006616,"The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon...","SRP-dependent cotranslational protein targeting to membrane, translocation",biological_process
61510,GO:0006617,"The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.","SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition",biological_process
61511,GO:0006620,"The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.",post-translational protein targeting to endoplasmic reticulum membrane,biological_process
61512,GO:0006621,"The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.",protein retention in ER lumen,biological_process
61513,GO:0006622,The process of directing proteins towards the lysosome using signals contained within the protein.,protein targeting to lysosome,biological_process
61514,GO:0006623,"The process of directing proteins towards the vacuole, usually using signals contained within the protein.",protein targeting to vacuole,biological_process
61515,GO:0006624,Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.,vacuolar protein processing,biological_process
61516,GO:0006625,"The process of directing proteins towards the peroxisome, usually using signals contained within the protein.",protein targeting to peroxisome,biological_process
61517,GO:0006629,"The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.",lipid metabolic process,biological_process
61518,GO:0006631,"The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.",fatty acid metabolic process,biological_process
61519,GO:0006633,"The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.",fatty acid biosynthetic process,biological_process
61520,GO:0006634,"The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.",hexadecanal biosynthetic process,biological_process
61521,GO:0006635,"A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).",fatty acid beta-oxidation,biological_process
61522,GO:0006636,"The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.",unsaturated fatty acid biosynthetic process,biological_process
61523,GO:0006637,"The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.",acyl-CoA metabolic process,biological_process
61524,GO:0006638,"The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.",neutral lipid metabolic process,biological_process
61525,GO:0006639,"The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.",acylglycerol metabolic process,biological_process
61526,GO:0006640,"The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.",monoacylglycerol biosynthetic process,biological_process
61527,GO:0006641,"The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.",triglyceride metabolic process,biological_process
61528,GO:0006642,"The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.",triglyceride mobilization,biological_process
61529,GO:0006644,"The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.",phospholipid metabolic process,biological_process
61530,GO:0006646,"The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.",phosphatidylethanolamine biosynthetic process,biological_process
61531,GO:0006647,"The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.",phosphatidyl-N-monomethylethanolamine biosynthetic process,biological_process
61532,GO:0006648,A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.,dihydrosphingosine-1-P pathway,biological_process
61533,GO:0006649,The transfer of a phospholipid from its site of synthesis to the plasma membrane.,phospholipid transfer to membrane,biological_process
61534,GO:0006650,"The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.",glycerophospholipid metabolic process,biological_process
61535,GO:0006651,"The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.",diacylglycerol biosynthetic process,biological_process
61536,GO:0006653,"The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.","1,2-diacyl-sn-glycero-3-phosphocholine metabolic process",biological_process
61537,GO:0006654,"The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.",phosphatidic acid biosynthetic process,biological_process
61538,GO:0006655,"The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.",phosphatidylglycerol biosynthetic process,biological_process
61539,GO:0006656,"The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.",phosphatidylcholine biosynthetic process,biological_process
61540,GO:0006657,The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.,CDP-choline pathway,biological_process
61541,GO:0006658,"The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.",phosphatidylserine metabolic process,biological_process
61542,GO:0006659,"The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.",phosphatidylserine biosynthetic process,biological_process
61543,GO:0006660,"The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.",phosphatidylserine catabolic process,biological_process
61544,GO:0006661,"The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.",phosphatidylinositol biosynthetic process,biological_process
61545,GO:0006663,"The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.",platelet activating factor biosynthetic process,biological_process
61546,GO:0006664,"The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.",glycolipid metabolic process,biological_process
61547,GO:0006665,"The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",sphingolipid metabolic process,biological_process
61548,GO:0006667,"The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.",sphinganine metabolic process,biological_process
61549,GO:0006668,"The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.",sphinganine-1-phosphate metabolic process,biological_process
61550,GO:0006669,"The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.",sphinganine-1-phosphate biosynthetic process,biological_process
61551,GO:0006670,"The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.",sphingosine metabolic process,biological_process
61552,GO:0006671,"The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.",phytosphingosine metabolic process,biological_process
61553,GO:0006672,"The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.",ceramide metabolic process,biological_process
61554,GO:0006673,"The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.",inositol phosphoceramide metabolic process,biological_process
61555,GO:0006675,"The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.",mannosyl-inositol phosphorylceramide metabolic process,biological_process
61556,GO:0006676,"The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.",mannosyl diphosphorylinositol ceramide metabolic process,biological_process
61557,GO:0006677,"The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.",glycosylceramide metabolic process,biological_process
61558,GO:0006678,"The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.",glucosylceramide metabolic process,biological_process
61559,GO:0006679,"The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound composed of a ceramide backbone covalently linked to a glucose. The glucose can be further elongated with the sequential addition of various carbohydrate units.",glucosylceramide biosynthetic process,biological_process
61560,GO:0006680,"The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.",glucosylceramide catabolic process,biological_process
61561,GO:0006681,"The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.",galactosylceramide metabolic process,biological_process
61562,GO:0006682,"The chemical reactions and pathways resulting in the formation of galactosylceramides, any composed of a ceramide backbone covalently linked to a galactose. The galactose can be sulfated or further elongated with one more monosaccharide often a sialic acid.",galactosylceramide biosynthetic process,biological_process
61563,GO:0006683,"The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.",galactosylceramide catabolic process,biological_process
61564,GO:0006684,"The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.",sphingomyelin metabolic process,biological_process
61565,GO:0006685,"The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.",sphingomyelin catabolic process,biological_process
61566,GO:0006686,"The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.",sphingomyelin biosynthetic process,biological_process
61567,GO:0006687,"The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.",glycosphingolipid metabolic process,biological_process
61568,GO:0006688,"The chemical reactions and pathways resulting in the formation of a glycosphingolipid, a compound composed of a ceramide backbone covalently linked to at least one carbohydrate moiety.",glycosphingolipid biosynthetic process,biological_process
61569,GO:0006689,"The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.",ganglioside catabolic process,biological_process
61570,GO:0006690,"The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.",icosanoid metabolic process,biological_process
61571,GO:0006691,"The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.",leukotriene metabolic process,biological_process
61572,GO:0006692,"The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.",prostanoid metabolic process,biological_process
61573,GO:0006693,"The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.",prostaglandin metabolic process,biological_process
61574,GO:0006694,"The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.",steroid biosynthetic process,biological_process
61575,GO:0006695,"The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",cholesterol biosynthetic process,biological_process
61576,GO:0006696,"The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.",ergosterol biosynthetic process,biological_process
61577,GO:0006697,"The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.",ecdysone biosynthetic process,biological_process
61578,GO:0006699,"The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.",bile acid biosynthetic process,biological_process
61579,GO:0006700,"The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.",C21-steroid hormone biosynthetic process,biological_process
61580,GO:0006701,"The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.",progesterone biosynthetic process,biological_process
61581,GO:0006702,"The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.",androgen biosynthetic process,biological_process
61582,GO:0006703,"The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.",estrogen biosynthetic process,biological_process
61583,GO:0006704,"The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.",glucocorticoid biosynthetic process,biological_process
61584,GO:0006705,"The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.",mineralocorticoid biosynthetic process,biological_process
61585,GO:0006706,"The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.",steroid catabolic process,biological_process
61586,GO:0006707,"The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",cholesterol catabolic process,biological_process
61587,GO:0006708,"The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.",ecdysone catabolic process,biological_process
61588,GO:0006709,"The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.",progesterone catabolic process,biological_process
61589,GO:0006710,"The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.",androgen catabolic process,biological_process
61590,GO:0006711,"The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.",estrogen catabolic process,biological_process
61591,GO:0006712,"The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.",mineralocorticoid catabolic process,biological_process
61592,GO:0006713,"The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.",glucocorticoid catabolic process,biological_process
61593,GO:0006714,"The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.",sesquiterpenoid metabolic process,biological_process
61594,GO:0006715,"The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.",farnesol biosynthetic process,biological_process
61595,GO:0006716,"The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.",juvenile hormone metabolic process,biological_process
61596,GO:0006718,"The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.",juvenile hormone biosynthetic process,biological_process
61597,GO:0006719,"The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.",juvenile hormone catabolic process,biological_process
61598,GO:0006720,"The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.",isoprenoid metabolic process,biological_process
61599,GO:0006721,"The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.",terpenoid metabolic process,biological_process
61600,GO:0006722,"The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units.",triterpenoid metabolic process,biological_process
61601,GO:0006723,"The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.",cuticle hydrocarbon biosynthetic process,biological_process
61602,GO:0006726,"The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.",eye pigment biosynthetic process,biological_process
61603,GO:0006727,"The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.",ommochrome biosynthetic process,biological_process
61604,GO:0006728,"The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.",pteridine biosynthetic process,biological_process
61605,GO:0006729,"The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.",tetrahydrobiopterin biosynthetic process,biological_process
61606,GO:0006730,The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.,one-carbon metabolic process,biological_process
61607,GO:0006738,"The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.",nicotinamide riboside catabolic process,biological_process
61608,GO:0006739,"The chemical reactions and pathways involving nicotinamide adenine dinucleotide phosphate (NADP+), a coenzyme that interconverts with its reduced form, NADPH, in many redox and biosynthetic reactions.",NADP+ metabolic process,biological_process
61609,GO:0006740,"A metabolic process that replenishes the cellular or compartmental pool of NADPH by transfer of reducing equivalents from a donor substrate to NADP+, independent of the route or compartment involved.",NADPH regeneration,biological_process
61610,GO:0006741,"The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide phosphate (NADP+) from NAD+. NADP+ is a coenzyme that interconverts with its reduced form, NADPH, in many redox and biosynthetic reactions.",NADP+ biosynthetic process,biological_process
61611,GO:0006742,"The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide phosphate (NADP+), a coenzyme that interconverts with its reduced form, NADPH, in many redox and biosynthetic reactions.",NADP+ catabolic process,biological_process
61612,GO:0006743,"The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.",ubiquinone metabolic process,biological_process
61613,GO:0006744,"The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.",ubiquinone biosynthetic process,biological_process
61614,GO:0006747,"The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.",FAD biosynthetic process,biological_process
61615,GO:0006749,"The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.",glutathione metabolic process,biological_process
61616,GO:0006750,"The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.",glutathione biosynthetic process,biological_process
61617,GO:0006751,"The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.",glutathione catabolic process,biological_process
61618,GO:0006753,The chemical reactions and pathways involving any phosphorylated nucleoside.,nucleoside phosphate metabolic process,biological_process
61619,GO:0006754,"The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.",ATP biosynthetic process,biological_process
61620,GO:0006756,"The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.",AMP phosphorylation,biological_process
61621,GO:0006760,"The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.",folic acid-containing compound metabolic process,biological_process
61622,GO:0006761,"The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate.",dihydrofolate biosynthetic process,biological_process
61623,GO:0006766,The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.,vitamin metabolic process,biological_process
61624,GO:0006768,"The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.",biotin metabolic process,biological_process
61625,GO:0006769,"The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.",nicotinamide metabolic process,biological_process
61626,GO:0006771,"The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).",riboflavin metabolic process,biological_process
61627,GO:0006772,"The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine metabolic process,biological_process
61628,GO:0006776,"The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.",vitamin A metabolic process,biological_process
61629,GO:0006777,"The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.",Mo-molybdopterin cofactor biosynthetic process,biological_process
61630,GO:0006778,The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.,porphyrin-containing compound metabolic process,biological_process
61631,GO:0006779,The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.,porphyrin-containing compound biosynthetic process,biological_process
61632,GO:0006780,The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.,uroporphyrinogen III biosynthetic process,biological_process
61633,GO:0006781,The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.,succinyl-CoA pathway,biological_process
61634,GO:0006783,"The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.",heme biosynthetic process,biological_process
61635,GO:0006784,"The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3.",heme A biosynthetic process,biological_process
61636,GO:0006785,"The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.",heme B biosynthetic process,biological_process
61637,GO:0006786,"The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.",heme C biosynthetic process,biological_process
61638,GO:0006787,The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.,porphyrin-containing compound catabolic process,biological_process
61639,GO:0006788,The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.,heme oxidation,biological_process
61640,GO:0006789,"The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.",bilirubin conjugation,biological_process
61641,GO:0006790,"The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.",sulfur compound metabolic process,biological_process
61642,GO:0006791,"A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is inco...",sulfur utilization,biological_process
61643,GO:0006792,"Any process that modulates the frequency, rate or extent of sulfur utilization.",regulation of sulfur utilization,biological_process
61644,GO:0006793,The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus.,phosphorus metabolic process,biological_process
61645,GO:0006794,"A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism.",phosphorus utilization,biological_process
61646,GO:0006795,"Any process that modulates the frequency, rate or extent of phosphorus utilization.",regulation of phosphorus utilization,biological_process
61647,GO:0006796,"The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.",phosphate-containing compound metabolic process,biological_process
61648,GO:0006797,"The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.",polyphosphate metabolic process,biological_process
61649,GO:0006798,"The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid.",polyphosphate catabolic process,biological_process
61650,GO:0006799,"The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.",polyphosphate biosynthetic process,biological_process
61651,GO:0006801,"The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.",superoxide metabolic process,biological_process
61652,GO:0006805,"The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",xenobiotic metabolic process,biological_process
61653,GO:0006808,"Any process that modulates the frequency, rate or extent of nitrogen utilization.",regulation of nitrogen utilization,biological_process
61654,GO:0006809,"The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.",nitric oxide biosynthetic process,biological_process
61655,GO:0006810,"The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.",transport,biological_process
61656,GO:0006811,"The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.",monoatomic ion transport,biological_process
61657,GO:0006812,"The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.",monoatomic cation transport,biological_process
61658,GO:0006813,"The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",potassium ion transport,biological_process
61659,GO:0006814,"The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sodium ion transport,biological_process
61660,GO:0006816,"The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",calcium ion transport,biological_process
61661,GO:0006817,"The directed movement of phosphate ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",phosphate ion transport,biological_process
61662,GO:0006820,"The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom.",monoatomic anion transport,biological_process
61663,GO:0006821,"The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",chloride transport,biological_process
61664,GO:0006824,"The directed movement of cobalt (Co2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cobalt ion transport,biological_process
61665,GO:0006825,"The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",copper ion transport,biological_process
61666,GO:0006826,"The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",iron ion transport,biological_process
61667,GO:0006828,"The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",manganese ion transport,biological_process
61668,GO:0006829,"The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",zinc ion transport,biological_process
61669,GO:0006833,"The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",water transport,biological_process
61670,GO:0006835,"The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",dicarboxylic acid transport,biological_process
61671,GO:0006836,"The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.",neurotransmitter transport,biological_process
61672,GO:0006839,"Transport of substances into, out of or within a mitochondrion.",mitochondrial transport,biological_process
61673,GO:0006842,"The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tricarboxylic acid transport,biological_process
61674,GO:0006843,"The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboxylate, into or out of a mitochondrial matrix.",mitochondrial citrate transmembrane transport,biological_process
61675,GO:0006846,"The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",acetate transport,biological_process
61676,GO:0006847,The directed movement of acetate across a plasma membrane.,plasma membrane acetate transport,biological_process
61677,GO:0006848,"The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",pyruvate transport,biological_process
61678,GO:0006849,"The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane.",plasma membrane pyruvate transport,biological_process
61679,GO:0006850,The process in which pyruvate is transported from the cytosol into the mitochondrial matrix.,pyruvate import into mitochondria,biological_process
61680,GO:0006851,"The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial calcium ion transmembrane transport,biological_process
61681,GO:0006853,"The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.",carnitine shuttle,biological_process
61682,GO:0006855,"The process in which a xenobiotic, a compound foreign to the organism exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",xenobiotic transmembrane transport,biological_process
61683,GO:0006856,"The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",eye pigment precursor transport,biological_process
61684,GO:0006857,"The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.",oligopeptide transport,biological_process
61685,GO:0006858,The transport of substances that occurs outside cells.,extracellular transport,biological_process
61686,GO:0006860,The directed extracellular movement of amino acids.,extracellular amino acid transport,biological_process
61687,GO:0006862,"The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.",nucleotide transport,biological_process
61688,GO:0006863,"The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",purine nucleobase transport,biological_process
61689,GO:0006864,"The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.",pyrimidine nucleotide transport,biological_process
61690,GO:0006865,"The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",amino acid transport,biological_process
61691,GO:0006867,"The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",asparagine transport,biological_process
61692,GO:0006868,"The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-glutamine transport,biological_process
61693,GO:0006869,"The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.",lipid transport,biological_process
61694,GO:0006873,A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.,intracellular monoatomic ion homeostasis,biological_process
61695,GO:0006874,A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell.,intracellular calcium ion homeostasis,biological_process
61696,GO:0006877,A homeostatic process involved in the maintenance of a steady state level of cobalt (Co2+) ions within a cell.,intracellular cobalt ion homeostasis,biological_process
61697,GO:0006878,A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.,intracellular copper ion homeostasis,biological_process
61698,GO:0006879,A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell.,intracellular iron ion homeostasis,biological_process
61699,GO:0006882,A homeostatic process involved in the maintenance of a steady state level of zinc ions within a cell.,intracellular zinc ion homeostasis,biological_process
61700,GO:0006883,A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell.,intracellular sodium ion homeostasis,biological_process
61701,GO:0006884,Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.,cell volume homeostasis,biological_process
61702,GO:0006885,"Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.",regulation of pH,biological_process
61703,GO:0006886,"The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.",intracellular protein transport,biological_process
61704,GO:0006887,"A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretio...",exocytosis,biological_process
61705,GO:0006888,"The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.",endoplasmic reticulum to Golgi vesicle-mediated transport,biological_process
61706,GO:0006890,"The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.","retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum",biological_process
61707,GO:0006891,"The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).",intra-Golgi vesicle-mediated transport,biological_process
61708,GO:0006892,"The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.",post-Golgi vesicle-mediated transport,biological_process
61709,GO:0006893,The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis.,Golgi to plasma membrane transport,biological_process
61710,GO:0006895,The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.,Golgi to endosome transport,biological_process
61711,GO:0006896,The directed movement of substances from the Golgi to the vacuole.,Golgi to vacuole transport,biological_process
61712,GO:0006897,A cellular process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.,endocytosis,biological_process
61713,GO:0006898,"An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and...",receptor-mediated endocytosis,biological_process
61714,GO:0006900,"The evagination of a membrane, resulting in formation of a vesicle.",vesicle budding from membrane,biological_process
61715,GO:0006901,A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.,vesicle coat assembly,biological_process
61716,GO:0006906,Fusion of the membrane of a transport vesicle with its target membrane.,vesicle fusion,biological_process
61717,GO:0006907,"An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.",pinocytosis,biological_process
61718,GO:0006909,"A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.",phagocytosis,biological_process
61719,GO:0006910,"The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.","phagocytosis, recognition",biological_process
61720,GO:0006911,"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.","phagocytosis, engulfment",biological_process
61721,GO:0006913,The directed movement of molecules between the nucleus and the cytoplasm.,nucleocytoplasmic transport,biological_process
61722,GO:0006914,"The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation.",autophagy,biological_process
61723,GO:0006915,"A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentati...",apoptotic process,biological_process
61724,GO:0006921,"The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.",cellular component disassembly involved in execution phase of apoptosis,biological_process
61725,GO:0006924,"A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.",activation-induced cell death of T cells,biological_process
61726,GO:0006925,"Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.",inflammatory cell apoptotic process,biological_process
61727,GO:0006929,The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.,substrate-dependent cell migration,biological_process
61728,GO:0006930,"The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.","substrate-dependent cell migration, cell extension",biological_process
61729,GO:0006931,"The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.","substrate-dependent cell migration, cell attachment to substrate",biological_process
61730,GO:0006932,"The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.","substrate-dependent cell migration, cell contraction",biological_process
61731,GO:0006933,"The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.",negative regulation of cell adhesion involved in substrate-bound cell migration,biological_process
61732,GO:0006934,"The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.","substrate-bound cell migration, adhesion receptor recycling",biological_process
61733,GO:0006935,"The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).",chemotaxis,biological_process
61734,GO:0006936,"A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.",muscle contraction,biological_process
61735,GO:0006937,"Any process that modulates the frequency, rate or extent of muscle contraction.",regulation of muscle contraction,biological_process
61736,GO:0006939,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.",smooth muscle contraction,biological_process
61737,GO:0006940,"Any process that modulates the frequency, rate or extent of smooth muscle contraction.",regulation of smooth muscle contraction,biological_process
61738,GO:0006941,"A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at...",striated muscle contraction,biological_process
61739,GO:0006942,"Any process that modulates the frequency, rate or extent of striated muscle contraction.",regulation of striated muscle contraction,biological_process
61740,GO:0006950,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",response to stress,biological_process
61741,GO:0006952,"Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.",defense response,biological_process
61742,GO:0006953,An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.,acute-phase response,biological_process
61743,GO:0006954,"The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.",inflammatory response,biological_process
61744,GO:0006955,Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.,immune response,biological_process
61745,GO:0006956,"Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.",complement activation,biological_process
61746,GO:0006957,Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.,"complement activation, alternative pathway",biological_process
61747,GO:0006958,"Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.","complement activation, classical pathway",biological_process
61748,GO:0006959,An immune response mediated through a body fluid.,humoral immune response,biological_process
61749,GO:0006962,"An immune response against bacteria, specific to males and mediated through a body fluid.",male-specific antibacterial humoral response,biological_process
61750,GO:0006963,"Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.",positive regulation of antibacterial peptide biosynthetic process,biological_process
61751,GO:0006964,"Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.",positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria,biological_process
61752,GO:0006965,"Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.",positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria,biological_process
61753,GO:0006967,"Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.",positive regulation of antifungal peptide biosynthetic process,biological_process
61754,GO:0006968,A defense response that is mediated by cells.,cellular defense response,biological_process
61755,GO:0006970,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",response to osmotic stress,biological_process
61756,GO:0006971,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.",hypotonic response,biological_process
61757,GO:0006972,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.",hyperosmotic response,biological_process
61758,GO:0006973,"The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.",intracellular accumulation of glycerol,biological_process
61759,GO:0006974,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.",DNA damage response,biological_process
61760,GO:0006979,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.",response to oxidative stress,biological_process
61761,GO:0006982,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.",response to lipid hydroperoxide,biological_process
61762,GO:0006983,The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.,ER overload response,biological_process
61763,GO:0006984,"The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.",ER-nucleus signaling pathway,biological_process
61764,GO:0006986,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.",response to unfolded protein,biological_process
61765,GO:0006991,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",response to sterol depletion,biological_process
61766,GO:0006995,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.",cellular response to nitrogen starvation,biological_process
61767,GO:0006996,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",organelle organization,biological_process
61768,GO:0006997,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.",nucleus organization,biological_process
61769,GO:0006998,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.",nuclear envelope organization,biological_process
61770,GO:0006999,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore.",nuclear pore organization,biological_process
61771,GO:0007000,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.",nucleolus organization,biological_process
61772,GO:0007004,The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.,telomere maintenance via telomerase,biological_process
61773,GO:0007005,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.",mitochondrion organization,biological_process
61774,GO:0007006,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.",mitochondrial membrane organization,biological_process
61775,GO:0007007,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.",inner mitochondrial membrane organization,biological_process
61776,GO:0007008,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.",outer mitochondrial membrane organization,biological_process
61777,GO:0007009,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.",plasma membrane organization,biological_process
61778,GO:0007010,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.",cytoskeleton organization,biological_process
61779,GO:0007014,The modification of actin by addition of ubiquitin groups.,actin ubiquitination,biological_process
61780,GO:0007015,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.",actin filament organization,biological_process
61781,GO:0007017,"Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.",microtubule-based process,biological_process
61782,GO:0007018,"A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.",microtubule-based movement,biological_process
61783,GO:0007019,The removal of tubulin heterodimers from one or both ends of a microtubule.,microtubule depolymerization,biological_process
61784,GO:0007020,The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).,microtubule nucleation,biological_process
61785,GO:0007021,The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.,tubulin complex assembly,biological_process
61786,GO:0007023,Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.,post-chaperonin tubulin folding pathway,biological_process
61787,GO:0007026,"Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.",negative regulation of microtubule depolymerization,biological_process
61788,GO:0007027,"Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.",negative regulation of axonemal microtubule depolymerization,biological_process
61789,GO:0007028,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",cytoplasm organization,biological_process
61790,GO:0007029,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.",endoplasmic reticulum organization,biological_process
61791,GO:0007030,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.",Golgi organization,biological_process
61792,GO:0007031,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.",peroxisome organization,biological_process
61793,GO:0007032,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.",endosome organization,biological_process
61794,GO:0007033,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.",vacuole organization,biological_process
61795,GO:0007034,"The directed movement of substances into, out of or within a vacuole.",vacuolar transport,biological_process
61796,GO:0007035,"Any process that reduces the pH of the vacuole, corresponding to an increase in hydrogen ion concentration.",vacuolar acidification,biological_process
61797,GO:0007036,Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.,vacuolar calcium ion homeostasis,biological_process
61798,GO:0007038,The directed movement of proteins imported into a cell by endocytosis to the vacuole.,endocytosed protein transport to vacuole,biological_process
61799,GO:0007039,"The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.",protein catabolic process in the vacuole,biological_process
61800,GO:0007040,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.",lysosome organization,biological_process
61801,GO:0007041,"The directed movement of substances into, out of or within a lysosome.",lysosomal transport,biological_process
61802,GO:0007042,"Any process that reduces the pH of the lysosomal lumen, corresponding to an increase in hydrogen ion concentration.",lysosomal lumen acidification,biological_process
61803,GO:0007043,"The aggregation, arrangement and bonding together of a set of components to form a junction between cells.",cell-cell junction assembly,biological_process
61804,GO:0007044,"The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.",cell-substrate junction assembly,biological_process
61805,GO:0007049,"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",cell cycle,biological_process
61806,GO:0007051,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.",spindle organization,biological_process
61807,GO:0007052,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.",mitotic spindle organization,biological_process
61808,GO:0007053,"The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.",spindle assembly involved in male meiosis,biological_process
61809,GO:0007054,The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.,spindle assembly involved in male meiosis I,biological_process
61810,GO:0007055,The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.,spindle assembly involved in male meiosis II,biological_process
61811,GO:0007056,"The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.",spindle assembly involved in female meiosis,biological_process
61812,GO:0007057,"The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.",spindle assembly involved in female meiosis I,biological_process
61813,GO:0007058,"The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.",spindle assembly involved in female meiosis II,biological_process
61814,GO:0007059,"The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.",chromosome segregation,biological_process
61815,GO:0007060,"The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.",male meiosis chromosome segregation,biological_process
61816,GO:0007062,The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.,sister chromatid cohesion,biological_process
61817,GO:0007063,"Any process that modulates the frequency, rate or extent of sister chromatid cohesion.",regulation of sister chromatid cohesion,biological_process
61818,GO:0007064,"The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.",mitotic sister chromatid cohesion,biological_process
61819,GO:0007065,The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.,male meiosis sister chromatid cohesion,biological_process
61820,GO:0007066,The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.,female meiosis sister chromatid cohesion,biological_process
61821,GO:0007076,The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.,mitotic chromosome condensation,biological_process
61822,GO:0007077,The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.,mitotic nuclear membrane disassembly,biological_process
61823,GO:0007078,The cell cycle process in which lamin is depolymerized.,lamin depolymerization,biological_process
61824,GO:0007079,"The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.",mitotic chromosome movement towards spindle pole,biological_process
61825,GO:0007080,"A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.",mitotic metaphase chromosome alignment,biological_process
61826,GO:0007084,The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.,mitotic nuclear membrane reassembly,biological_process
61827,GO:0007087,The cell cycle process in which nuclear pore complexes reform during mitotic cell division.,mitotic nuclear pore complex reassembly,biological_process
61828,GO:0007088,"Any process that modulates the frequency, rate or extent of mitosis.",regulation of mitotic nuclear division,biological_process
61829,GO:0007089,A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.,traversing start control point of mitotic cell cycle,biological_process
61830,GO:0007091,"The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.",metaphase/anaphase transition of mitotic cell cycle,biological_process
61831,GO:0007093,A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.,mitotic cell cycle checkpoint signaling,biological_process
61832,GO:0007094,"A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC).",mitotic spindle assembly checkpoint signaling,biological_process
61833,GO:0007095,A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.,mitotic G2 DNA damage checkpoint signaling,biological_process
61834,GO:0007096,Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.,regulation of exit from mitosis,biological_process
61835,GO:0007097,The directed movement of the nucleus to a specific location within a cell.,nuclear migration,biological_process
61836,GO:0007098,The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.,centrosome cycle,biological_process
61837,GO:0007099,"The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.",centriole replication,biological_process
61838,GO:0007100,Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.,mitotic centrosome separation,biological_process
61839,GO:0007105,The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions.,"cytokinesis, division site positioning",biological_process
61840,GO:0007107,"Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.",membrane addition at site of cytokinesis,biological_process
61841,GO:0007110,"A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.",meiosis I cytokinesis,biological_process
61842,GO:0007111,"A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.",meiosis II cytokinesis,biological_process
61843,GO:0007112,A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.,male meiosis cytokinesis,biological_process
61844,GO:0007113,"A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.",endomitotic cell cycle,biological_process
61845,GO:0007114,"A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.",cell budding,biological_process
61846,GO:0007116,"Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.",regulation of cell budding,biological_process
61847,GO:0007117,The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.,budding cell bud growth,biological_process
61848,GO:0007118,"Growth at the tip of a bud, in a cell that reproduces by budding.",budding cell apical bud growth,biological_process
61849,GO:0007119,"Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.",budding cell isotropic bud growth,biological_process
61850,GO:0007120,The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.,axial cellular bud site selection,biological_process
61851,GO:0007121,The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.,bipolar cellular bud site selection,biological_process
61852,GO:0007124,"The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.",pseudohyphal growth,biological_process
61853,GO:0007127,"The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.",meiosis I,biological_process
61854,GO:0007128,The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.,meiotic prophase I,biological_process
61855,GO:0007129,The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.,homologous chromosome pairing at meiosis,biological_process
61856,GO:0007130,The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.,synaptonemal complex assembly,biological_process
61857,GO:0007131,The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.,reciprocal meiotic recombination,biological_process
61858,GO:0007132,"The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.",meiotic metaphase I,biological_process
61859,GO:0007133,The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.,meiotic anaphase I,biological_process
61860,GO:0007134,The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.,meiotic telophase I,biological_process
61861,GO:0007135,"The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.",meiosis II,biological_process
61862,GO:0007136,The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.,meiotic prophase II,biological_process
61863,GO:0007137,"The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.",meiotic metaphase II,biological_process
61864,GO:0007138,The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.,meiotic anaphase II,biological_process
61865,GO:0007139,The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.,meiotic telophase II,biological_process
61866,GO:0007140,A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.,male meiotic nuclear division,biological_process
61867,GO:0007141,"A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.",male meiosis I,biological_process
61868,GO:0007142,"A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.",male meiosis II,biological_process
61869,GO:0007143,A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.,female meiotic nuclear division,biological_process
61870,GO:0007144,The cell cycle process in which the first meiotic division occurs in the female germline.,female meiosis I,biological_process
61871,GO:0007146,"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.",meiotic recombination nodule assembly,biological_process
61872,GO:0007147,The cell cycle process in which the second meiotic division occurs in the female germline.,female meiosis II,biological_process
61873,GO:0007154,"Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",cell communication,biological_process
61874,GO:0007155,"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.",cell adhesion,biological_process
61875,GO:0007156,The attachment of an adhesion molecule in one cell to an identical molecule in an adjacent cell.,homophilic cell-cell adhesion,biological_process
61876,GO:0007157,The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.,heterophilic cell-cell adhesion,biological_process
61877,GO:0007158,The attachment of a neuron to another cell via adhesion molecules.,neuron cell-cell adhesion,biological_process
61878,GO:0007159,The attachment of a leukocyte to another cell via adhesion molecules.,leukocyte cell-cell adhesion,biological_process
61879,GO:0007160,The binding of a cell to the extracellular matrix via adhesion molecules.,cell-matrix adhesion,biological_process
61880,GO:0007161,The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.,calcium-independent cell-matrix adhesion,biological_process
61881,GO:0007162,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.",negative regulation of cell adhesion,biological_process
61882,GO:0007163,"Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.",establishment or maintenance of cell polarity,biological_process
61883,GO:0007164,"Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.",establishment of tissue polarity,biological_process
61884,GO:0007165,"The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation ...",signal transduction,biological_process
61885,GO:0007166,"The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription.",cell surface receptor signaling pathway,biological_process
61886,GO:0007167,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.",enzyme-linked receptor protein signaling pathway,biological_process
61887,GO:0007168,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and converts GTP to cGMP upon activation, and ending with the regulation of a downstream cellular process, e.g. transcription.",receptor guanylyl cyclase signaling pathway,biological_process
61888,GO:0007169,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.",cell surface receptor protein tyrosine kinase signaling pathway,biological_process
61889,GO:0007171,Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.,activation of transmembrane receptor protein tyrosine kinase activity,biological_process
61890,GO:0007172,"The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.",signal complex assembly,biological_process
61891,GO:0007173,"The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.",epidermal growth factor receptor signaling pathway,biological_process
61892,GO:0007174,"The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.",epidermal growth factor catabolic process,biological_process
61893,GO:0007175,"Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.",negative regulation of epidermal growth factor-activated receptor activity,biological_process
61894,GO:0007178,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.",cell surface receptor protein serine/threonine kinase signaling pathway,biological_process
61895,GO:0007179,"The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",transforming growth factor beta receptor signaling pathway,biological_process
61896,GO:0007181,"The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.",transforming growth factor beta receptor complex assembly,biological_process
61897,GO:0007185,"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.",cell surface receptor protein tyrosine phosphatase signaling pathway,biological_process
61898,GO:0007186,"The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from...",G protein-coupled receptor signaling pathway,biological_process
61899,GO:0007187,A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.,"G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger",biological_process
61900,GO:0007188,A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP).,adenylate cyclase-modulating G protein-coupled receptor signaling pathway,biological_process
61901,GO:0007189,"A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.",adenylate cyclase-activating G protein-coupled receptor signaling pathway,biological_process
61902,GO:0007190,Any process that initiates the activity of the inactive enzyme adenylate cyclase.,activation of adenylate cyclase activity,biological_process
61903,GO:0007191,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating dopamine receptor signaling pathway,biological_process
61904,GO:0007192,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating serotonin receptor signaling pathway,biological_process
61905,GO:0007193,A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP).,adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway,biological_process
61906,GO:0007194,"Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.",negative regulation of adenylate cyclase activity,biological_process
61907,GO:0007195,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting dopamine receptor signaling pathway,biological_process
61908,GO:0007196,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway,biological_process
61909,GO:0007197,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway,biological_process
61910,GO:0007198,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting serotonin receptor signaling pathway,biological_process
61911,GO:0007199,"The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).",G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger,biological_process
61912,GO:0007200,"A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). IP3 regulates the opening of calcium channels in intracellular calcium store, leading to the release of calcium into the cytosol. Calcium and DAG activate protein kinase C (PKC), which in turn activates downstream effectors.",phospholipase C-activating G protein-coupled receptor signaling pathway,biological_process
61913,GO:0007204,Any process that increases the concentration of calcium ions in the cytosol.,positive regulation of cytosolic calcium ion concentration,biological_process
61914,GO:0007206,"A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating G protein-coupled glutamate receptor signaling pathway,biological_process
61915,GO:0007207,"A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway,biological_process
61916,GO:0007208,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating serotonin receptor signaling pathway,biological_process
61917,GO:0007209,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating tachykinin receptor signaling pathway,biological_process
61918,GO:0007210,The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.,serotonin receptor signaling pathway,biological_process
61919,GO:0007211,"A G protein-coupled receptor signaling pathway initiated by octopamine or tyramine binding to their receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription, and ending with the regulation of a downstream cellular process. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters.",octopamine or tyramine signaling pathway,biological_process
61920,GO:0007212,"A G protein-coupled receptor signaling pathway initiated by a dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",G protein-coupled dopamine receptor signaling pathway,biological_process
61921,GO:0007213,"A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.",G protein-coupled acetylcholine receptor signaling pathway,biological_process
61922,GO:0007214,"The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.",gamma-aminobutyric acid signaling pathway,biological_process
61923,GO:0007215,"The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",glutamate receptor signaling pathway,biological_process
61924,GO:0007216,"A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",G protein-coupled glutamate receptor signaling pathway,biological_process
61925,GO:0007217,"A G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. Tachykinin is a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2).",tachykinin receptor signaling pathway,biological_process
61926,GO:0007218,"A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",neuropeptide signaling pathway,biological_process
61927,GO:0007219,"The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",Notch signaling pathway,biological_process
61928,GO:0007220,"The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.",Notch receptor processing,biological_process
61929,GO:0007221,"The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.",positive regulation of transcription of Notch receptor target,biological_process
61930,GO:0007223,A type of non-canonical Wnt signaling in which Wnt binding to its receptor on the surface of a target cell leads to an increase in intracellular calcium and activation of protein kinase C (PKC).,"Wnt signaling pathway, calcium modulating pathway",biological_process
61931,GO:0007224,The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.,smoothened signaling pathway,biological_process
61932,GO:0007225,"The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.",patched ligand maturation,biological_process
61933,GO:0007229,"The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",integrin-mediated signaling pathway,biological_process
61934,GO:0007231,The series of molecular signals initiated in response to osmotic change.,osmosensory signaling pathway,biological_process
61935,GO:0007232,"The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.",osmosensory signaling pathway via Sho1 osmosensor,biological_process
61936,GO:0007234,"The series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. In S.cerevisiae, the osmosensor is the histidine kinase Sln1.",osmosensory signaling via phosphorelay pathway,biological_process
61937,GO:0007249,"An intracellular signaling cassette characterized by the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB, also known as the canonical NF-kappaB signaling cascade. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering...",canonical NF-kappaB signal transduction,biological_process
61938,GO:0007250,The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.,activation of NF-kappaB-inducing kinase activity,biological_process
61939,GO:0007252,"The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.",I-kappaB phosphorylation,biological_process
61940,GO:0007254,"A MAPK cascade containing at least the JNK (MAPK8) MAP kinase. It starts with the activation of JUN3K (a MAPK3K), which activates JNKK a MAP2K), which in turn activates JNK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The JNK cascade is activated by stress signals, as well as by G protein-coupled receptors, growth factors, and cytokines, and results in cellular responses such as ce...",JNK cascade,biological_process
61941,GO:0007258,The process of introducing a phosphate group into a JUN protein.,JUN phosphorylation,biological_process
61942,GO:0007259,"A cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.",cell surface receptor signaling pathway via JAK-STAT,biological_process
61943,GO:0007260,The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.,tyrosine phosphorylation of STAT protein,biological_process
61944,GO:0007264,An intracellular signaling cassette in which a small monomeric GTPase relays a signal.,small GTPase-mediated signal transduction,biological_process
61945,GO:0007265,An intracellular signaling cassette in which a small monomeric GTPase of the Ras subfamily relays a signal.,Ras protein signal transduction,biological_process
61946,GO:0007266,An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.,Rho protein signal transduction,biological_process
61947,GO:0007267,"Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.",cell-cell signaling,biological_process
61948,GO:0007268,"The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked tr...",chemical synaptic transmission,biological_process
61949,GO:0007269,The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.,neurotransmitter secretion,biological_process
61950,GO:0007270,The process of synaptic transmission from a neuron to another neuron across a synapse.,neuron-neuron synaptic transmission,biological_process
61951,GO:0007271,"The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arri...","synaptic transmission, cholinergic",biological_process
61952,GO:0007272,The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.,ensheathment of neurons,biological_process
61953,GO:0007274,"The process of synaptic transmission from a neuron to a muscle, across a synapse.",neuromuscular synaptic transmission,biological_process
61954,GO:0007275,The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).,multicellular organism development,biological_process
61955,GO:0007276,The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.,gamete generation,biological_process
61956,GO:0007277,"The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure.",pole cell development,biological_process
61957,GO:0007278,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.",pole cell fate determination,biological_process
61958,GO:0007279,Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.,pole cell formation,biological_process
61959,GO:0007281,"The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.",germ cell development,biological_process
61960,GO:0007282,Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.,cystoblast division,biological_process
61961,GO:0007283,The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.,spermatogenesis,biological_process
61962,GO:0007284,The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).,spermatogonial cell division,biological_process
61963,GO:0007285,The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.,primary spermatocyte growth,biological_process
61964,GO:0007286,"The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.",spermatid development,biological_process
61965,GO:0007287,"Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.",Nebenkern assembly,biological_process
61966,GO:0007288,"The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.",sperm axoneme assembly,biological_process
61967,GO:0007289,The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.,spermatid nucleus differentiation,biological_process
61968,GO:0007290,"The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.",spermatid nucleus elongation,biological_process
61969,GO:0007291,The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.,sperm individualization,biological_process
61970,GO:0007292,Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.,female gamete generation,biological_process
61971,GO:0007293,"Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.",germarium-derived egg chamber formation,biological_process
61972,GO:0007294,"The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.",germarium-derived oocyte fate determination,biological_process
61973,GO:0007295,Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.,growth of a germarium-derived egg chamber,biological_process
61974,GO:0007296,The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.,vitellogenesis,biological_process
61975,GO:0007297,"The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.",follicle cell of egg chamber migration,biological_process
61976,GO:0007298,The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.,border follicle cell migration,biological_process
61977,GO:0007299,"The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.",follicle cell of egg chamber-cell adhesion,biological_process
61978,GO:0007300,"Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.",ovarian nurse cell to oocyte transport,biological_process
61979,GO:0007301,Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.,female germline ring canal formation,biological_process
61980,GO:0007302,Attachment of the nurse cell nucleus to the plasma membrane.,nurse cell nucleus anchoring,biological_process
61981,GO:0007304,The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.,chorion-containing eggshell formation,biological_process
61982,GO:0007305,Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.,vitelline membrane formation involved in chorion-containing eggshell formation,biological_process
61983,GO:0007306,"Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.",egg chorion assembly,biological_process
61984,GO:0007307,"Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.",eggshell chorion gene amplification,biological_process
61985,GO:0007308,"The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.",oocyte construction,biological_process
61986,GO:0007309,"The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.",oocyte axis specification,biological_process
61987,GO:0007310,"The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.",oocyte dorsal/ventral axis specification,biological_process
61988,GO:0007311,"Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.","maternal specification of dorsal/ventral axis, oocyte, germ-line encoded",biological_process
61989,GO:0007312,The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.,oocyte nucleus migration involved in oocyte dorsal/ventral axis specification,biological_process
61990,GO:0007313,"Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.","maternal specification of dorsal/ventral axis, oocyte, soma encoded",biological_process
61991,GO:0007314,Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.,oocyte anterior/posterior axis specification,biological_process
61992,GO:0007315,"The aggregation, arrangement and bonding together of a set of components to form the germ plasm, the differentiated cytoplasm associated with an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.",germ plasm assembly,biological_process
61993,GO:0007316,"Any process in which RNA is transported to, or maintained in, the germ plasm.",germ plasm RNA localization,biological_process
61994,GO:0007317,"Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the germ plasm.",regulation of germ plasm oskar mRNA localization,biological_process
61995,GO:0007318,"Any process in which a protein is transported to, or maintained in, the germ plasm.",germ plasm protein localization,biological_process
61996,GO:0007319,"Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.",negative regulation of oskar mRNA translation,biological_process
61997,GO:0007320,The introduction of semen or sperm into the genital tract of a female.,insemination,biological_process
61998,GO:0007321,The physical displacement of sperm stored from previous mating encounters.,sperm displacement,biological_process
61999,GO:0007323,"The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.",peptide pheromone maturation,biological_process
62000,GO:0007338,The union of male and female gametes to form a zygote.,single fertilization,biological_process
62001,GO:0007339,The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.,binding of sperm to zona pellucida,biological_process
62002,GO:0007340,"The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.",acrosome reaction,biological_process
62003,GO:0007341,"The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.",penetration of zona pellucida,biological_process
62004,GO:0007342,"The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.",fusion of sperm to egg plasma membrane involved in single fertilization,biological_process
62005,GO:0007343,"The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.",egg activation,biological_process
62006,GO:0007344,The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.,pronuclear fusion,biological_process
62007,GO:0007346,Any process that modulates the rate or extent of progress through the mitotic cell cycle.,regulation of mitotic cell cycle,biological_process
62008,GO:0007347,A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.,regulation of preblastoderm mitotic cell cycle,biological_process
62009,GO:0007348,A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle.,regulation of syncytial blastoderm mitotic cell cycle,biological_process
62010,GO:0007349,The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.,cellularization,biological_process
62011,GO:0007350,The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.,blastoderm segmentation,biological_process
62012,GO:0007351,"Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.",tripartite regional subdivision,biological_process
62013,GO:0007352,"The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.",zygotic specification of dorsal/ventral axis,biological_process
62014,GO:0007354,"The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.","zygotic determination of anterior/posterior axis, embryo",biological_process
62015,GO:0007355,Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.,anterior region determination,biological_process
62016,GO:0007356,Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.,thorax and anterior abdomen determination,biological_process
62017,GO:0007359,The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.,posterior abdomen determination,biological_process
62018,GO:0007362,Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.,terminal region determination,biological_process
62019,GO:0007365,The regionalization process that divides the spatial regions of an embryo into serially repeated regions.,periodic partitioning,biological_process
62020,GO:0007366,"Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.",periodic partitioning by pair rule gene,biological_process
62021,GO:0007367,Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.,segment polarity determination,biological_process
62022,GO:0007368,"The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.",determination of left/right symmetry,biological_process
62023,GO:0007369,"A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.",gastrulation,biological_process
62024,GO:0007370,"Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.",ventral furrow formation,biological_process
62025,GO:0007371,The regionalization process in which the area where the ventral midline will form is specified.,ventral midline determination,biological_process
62026,GO:0007374,"Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior.",posterior midgut invagination,biological_process
62027,GO:0007375,Internalization of the anterior midgut into the interior of the embryo.,anterior midgut invagination,biological_process
62028,GO:0007376,"Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.",cephalic furrow formation,biological_process
62029,GO:0007377,"Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.",germ-band extension,biological_process
62030,GO:0007378,"Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.",amnioserosa formation,biological_process
62031,GO:0007379,The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.,segment specification,biological_process
62032,GO:0007380,The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, head",biological_process
62033,GO:0007381,The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, labial segment",biological_process
62034,GO:0007382,The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, maxillary segment",biological_process
62035,GO:0007383,The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, antennal segment",biological_process
62036,GO:0007384,The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, thorax",biological_process
62037,GO:0007385,The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, abdomen",biological_process
62038,GO:0007386,The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.,compartment pattern specification,biological_process
62039,GO:0007387,The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.,anterior compartment pattern formation,biological_process
62040,GO:0007388,The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.,posterior compartment specification,biological_process
62041,GO:0007389,Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.,pattern specification process,biological_process
62042,GO:0007390,"The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.",germ-band shortening,biological_process
62043,GO:0007391,The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.,dorsal closure,biological_process
62044,GO:0007392,Events that occur at the start of dorsal closure.,initiation of dorsal closure,biological_process
62045,GO:0007393,"The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.","dorsal closure, leading edge cell fate determination",biological_process
62046,GO:0007394,The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis.,"dorsal closure, elongation of leading edge cells",biological_process
62047,GO:0007395,Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.,"dorsal closure, spreading of leading edge cells",biological_process
62048,GO:0007396,Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole.,suture of dorsal opening,biological_process
62049,GO:0007398,"The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.",ectoderm development,biological_process
62050,GO:0007399,"The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.",nervous system development,biological_process
62051,GO:0007400,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.",neuroblast fate determination,biological_process
62052,GO:0007402,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.",ganglion mother cell fate determination,biological_process
62053,GO:0007403,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed.",glial cell fate determination,biological_process
62054,GO:0007405,The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.,neuroblast proliferation,biological_process
62055,GO:0007406,"Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.",negative regulation of neuroblast proliferation,biological_process
62056,GO:0007407,A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.,neuroblast activation,biological_process
62057,GO:0007409,"De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.",axonogenesis,biological_process
62058,GO:0007411,The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.,axon guidance,biological_process
62059,GO:0007412,The process in which an axon recognizes and binds to a set of cells with which it may form stable connections.,axon target recognition,biological_process
62060,GO:0007413,"The collection of axons into a bundle of rods, known as a fascicle.",axonal fasciculation,biological_process
62061,GO:0007414,Separation of axons away from a bundle of axons known as a fascicle.,axonal defasciculation,biological_process
62062,GO:0007415,Separation of a motor axon away from a bundle of axons known as a fascicle.,defasciculation of motor neuron axon,biological_process
62063,GO:0007416,"The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).",synapse assembly,biological_process
62064,GO:0007417,"The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",central nervous system development,biological_process
62065,GO:0007418,"The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerv...",ventral midline development,biological_process
62066,GO:0007419,"The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.",ventral cord development,biological_process
62067,GO:0007420,"The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).",brain development,biological_process
62068,GO:0007421,"The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.",stomatogastric nervous system development,biological_process
62069,GO:0007422,"The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.",peripheral nervous system development,biological_process
62070,GO:0007423,"The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.",sensory organ development,biological_process
62071,GO:0007424,"The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.",open tracheal system development,biological_process
62072,GO:0007425,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.","epithelial cell fate determination, open tracheal system",biological_process
62073,GO:0007426,The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.,"tracheal outgrowth, open tracheal system",biological_process
62074,GO:0007427,The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.,"epithelial cell migration, open tracheal system",biological_process
62075,GO:0007428,"Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.","primary branching, open tracheal system",biological_process
62076,GO:0007429,Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster.,"secondary branching, open tracheal system",biological_process
62077,GO:0007430,Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.,"terminal branching, open tracheal system",biological_process
62078,GO:0007431,"The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.",salivary gland development,biological_process
62079,GO:0007432,"Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.",salivary gland boundary specification,biological_process
62080,GO:0007433,"Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.",larval salivary gland boundary specification,biological_process
62081,GO:0007434,"Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.",adult salivary gland boundary specification,biological_process
62082,GO:0007435,The process in which the anatomical structures of the salivary gland are generated and organized.,salivary gland morphogenesis,biological_process
62083,GO:0007436,"The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.",larval salivary gland morphogenesis,biological_process
62084,GO:0007437,The process in which the anatomical structures of the adult salivary gland are generated and organized.,adult salivary gland morphogenesis,biological_process
62085,GO:0007438,"The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.",oenocyte development,biological_process
62086,GO:0007439,"The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.",ectodermal digestive tract development,biological_process
62087,GO:0007440,The process in which the anatomical structures of the foregut are generated and organized.,foregut morphogenesis,biological_process
62088,GO:0007441,The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.,anterior midgut (ectodermal) morphogenesis,biological_process
62089,GO:0007442,The process in which the anatomical structures of the hindgut are generated and organized.,hindgut morphogenesis,biological_process
62090,GO:0007443,"The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.",Malpighian tubule morphogenesis,biological_process
62091,GO:0007444,"The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).",imaginal disc development,biological_process
62092,GO:0007445,"Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment.",determination of imaginal disc primordium,biological_process
62093,GO:0007446,"The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.",imaginal disc growth,biological_process
62094,GO:0007447,"The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.",imaginal disc pattern formation,biological_process
62095,GO:0007448,"The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.","anterior/posterior pattern specification, imaginal disc",biological_process
62096,GO:0007449,"The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.","proximal/distal pattern formation, imaginal disc",biological_process
62097,GO:0007450,"The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.","dorsal/ventral pattern formation, imaginal disc",biological_process
62098,GO:0007451,"Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.","dorsal/ventral lineage restriction, imaginal disc",biological_process
62099,GO:0007453,"The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus.",clypeo-labral disc morphogenesis,biological_process
62100,GO:0007454,The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.,labial disc morphogenesis,biological_process
62101,GO:0007455,"The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.",eye-antennal disc morphogenesis,biological_process
62102,GO:0007458,"The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.",progression of morphogenetic furrow involved in compound eye morphogenesis,biological_process
62103,GO:0007460,The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.,R8 cell fate commitment,biological_process
62104,GO:0007462,The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres.,R1/R6 cell fate commitment,biological_process
62105,GO:0007463,The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres.,R2/R5 cell fate commitment,biological_process
62106,GO:0007464,The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.,R3/R4 cell fate commitment,biological_process
62107,GO:0007465,The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.,R7 cell fate commitment,biological_process
62108,GO:0007469,"The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.",antennal development,biological_process
62109,GO:0007470,The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.,prothoracic disc morphogenesis,biological_process
62110,GO:0007472,"The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.",wing disc morphogenesis,biological_process
62111,GO:0007473,"The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.",wing disc proximal/distal pattern formation,biological_process
62112,GO:0007474,The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.,imaginal disc-derived wing vein specification,biological_process
62113,GO:0007475,The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.,apposition of dorsal and ventral imaginal disc-derived wing surfaces,biological_process
62114,GO:0007476,The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.,imaginal disc-derived wing morphogenesis,biological_process
62115,GO:0007477,"The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.",notum development,biological_process
62116,GO:0007478,"The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.",leg disc morphogenesis,biological_process
62117,GO:0007479,"The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.",leg disc proximal/distal pattern formation,biological_process
62118,GO:0007480,The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.,imaginal disc-derived leg morphogenesis,biological_process
62119,GO:0007481,"The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.",haltere disc morphogenesis,biological_process
62120,GO:0007482,"The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.",haltere development,biological_process
62121,GO:0007483,"The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.",genital disc morphogenesis,biological_process
62122,GO:0007484,"The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.",imaginal disc-derived genitalia development,biological_process
62123,GO:0007485,"The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.",imaginal disc-derived male genitalia development,biological_process
62124,GO:0007486,"The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.",imaginal disc-derived female genitalia development,biological_process
62125,GO:0007487,"The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.",analia development,biological_process
62126,GO:0007488,The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.,histoblast morphogenesis,biological_process
62127,GO:0007489,The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells.,maintenance of imaginal histoblast diploidy,biological_process
62128,GO:0007490,The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.,tergite morphogenesis,biological_process
62129,GO:0007491,The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.,sternite morphogenesis,biological_process
62130,GO:0007492,"The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.",endoderm development,biological_process
62131,GO:0007493,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",endodermal cell fate determination,biological_process
62132,GO:0007494,"The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.",midgut development,biological_process
62133,GO:0007495,The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.,visceral mesoderm-endoderm interaction involved in midgut development,biological_process
62134,GO:0007496,"The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.",anterior midgut development,biological_process
62135,GO:0007497,"The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.",posterior midgut development,biological_process
62136,GO:0007498,"The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.",mesoderm development,biological_process
62137,GO:0007499,A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.,ectoderm and mesoderm interaction,biological_process
62138,GO:0007500,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",mesodermal cell fate determination,biological_process
62139,GO:0007501,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",mesodermal cell fate specification,biological_process
62140,GO:0007502,"The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.",digestive tract mesoderm development,biological_process
62141,GO:0007503,"The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.",fat body development,biological_process
62142,GO:0007504,"The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.",larval fat body development,biological_process
62143,GO:0007505,"The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.",adult fat body development,biological_process
62144,GO:0007506,"The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.",gonadal mesoderm development,biological_process
62145,GO:0007507,"The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.",heart development,biological_process
62146,GO:0007508,"The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.",larval heart development,biological_process
62147,GO:0007509,The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.,mesoderm migration involved in gastrulation,biological_process
62148,GO:0007510,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast cell fate determination,biological_process
62149,GO:0007512,"The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.",adult heart development,biological_process
62150,GO:0007516,"The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.",hemocyte development,biological_process
62151,GO:0007517,"The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.",muscle organ development,biological_process
62152,GO:0007518,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fate determination,biological_process
62153,GO:0007519,"The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.",skeletal muscle tissue development,biological_process
62154,GO:0007520,"A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fusion,biological_process
62155,GO:0007521,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.",muscle cell fate determination,biological_process
62156,GO:0007522,"The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.",visceral muscle development,biological_process
62157,GO:0007523,"The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure.",larval visceral muscle development,biological_process
62158,GO:0007524,"The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.",adult visceral muscle development,biological_process
62159,GO:0007525,"The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.",somatic muscle development,biological_process
62160,GO:0007526,"The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.",larval somatic muscle development,biological_process
62161,GO:0007527,"The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.",adult somatic muscle development,biological_process
62162,GO:0007528,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.",neuromuscular junction development,biological_process
62163,GO:0007529,The biological process in which a synapse between a motor neuron and a muscle is initially formed.,establishment of synaptic specificity at neuromuscular junction,biological_process
62164,GO:0007530,Any process that establishes and transmits the specification of sexual status of an individual organism.,sex determination,biological_process
62165,GO:0007531,Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.,mating type determination,biological_process
62166,GO:0007532,"Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription.","regulation of mating-type specific transcription, DNA-templated",biological_process
62167,GO:0007533,The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.,mating type switching,biological_process
62168,GO:0007534,The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.,gene conversion at mating-type locus,biological_process
62169,GO:0007535,"The process that determines which donor locus a cell uses, in preference to another, in mating type switching.",donor selection,biological_process
62170,GO:0007536,"The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.",activation of recombination (HML),biological_process
62171,GO:0007537,"The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.",inactivation of recombination (HML),biological_process
62172,GO:0007538,The sex determination process that results in the initial specification of sexual status of an individual organism.,primary sex determination,biological_process
62173,GO:0007539,"The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.","primary sex determination, soma",biological_process
62174,GO:0007540,The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it.,"sex determination, establishment of X:A ratio",biological_process
62175,GO:0007541,The developmental process in which an organism interprets its X to autosomal chromosomal complement.,"sex determination, primary response to X:A ratio",biological_process
62176,GO:0007542,"The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.","primary sex determination, germ-line",biological_process
62177,GO:0007543,The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.,"sex determination, somatic-gonadal interaction",biological_process
62178,GO:0007548,The establishment of the sex of an organism by physical differentiation.,sex differentiation,biological_process
62179,GO:0007549,Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.,sex-chromosome dosage compensation,biological_process
62180,GO:0007552,"A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.",metamorphosis,biological_process
62181,GO:0007553,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.",regulation of ecdysteroid metabolic process,biological_process
62182,GO:0007554,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.",regulation of ecdysteroid biosynthetic process,biological_process
62183,GO:0007555,"Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell.",regulation of ecdysteroid secretion,biological_process
62184,GO:0007557,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.",regulation of juvenile hormone biosynthetic process,biological_process
62185,GO:0007558,"Any process that modulates the frequency, rate or extent of juvenile hormone secretion.",regulation of juvenile hormone secretion,biological_process
62186,GO:0007560,"The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.",imaginal disc morphogenesis,biological_process
62187,GO:0007561,"The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.",imaginal disc eversion,biological_process
62188,GO:0007562,The emergence of an adult insect from a pupa case.,eclosion,biological_process
62189,GO:0007563,"Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.",regulation of eclosion,biological_process
62190,GO:0007564,"Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.",regulation of chitin-based cuticle tanning,biological_process
62191,GO:0007565,The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.,female pregnancy,biological_process
62192,GO:0007566,Attachment of the blastocyst to the uterine lining.,embryo implantation,biological_process
62193,GO:0007567,The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.,parturition,biological_process
62194,GO:0007584,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.",response to nutrient,biological_process
62195,GO:0007585,"The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.",respiratory gaseous exchange by respiratory system,biological_process
62196,GO:0007586,"The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",digestion,biological_process
62197,GO:0007588,"The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.",excretion,biological_process
62198,GO:0007589,The controlled release of a fluid by a cell or tissue in an animal.,body fluid secretion,biological_process
62199,GO:0007591,"The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.","molting cycle, chitin-based cuticle",biological_process
62200,GO:0007593,The process of hardening of a chitin-based cuticle.,chitin-based cuticle sclerotization,biological_process
62201,GO:0007594,The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation.,puparial adhesion,biological_process
62202,GO:0007595,The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.,lactation,biological_process
62203,GO:0007596,"The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.",blood coagulation,biological_process
62204,GO:0007597,"A protein activation cascade that initiates blood coagulation, triggered when Factor XII, prekallikrein (PK) and high-molecular-weight kininogen  (HK) assemble on a suitable surface or polymer. This results in the reciprocal activation of factor XII to Factor XIIa by kallikrein, and PK to kallikrein by Factor XIIa. The resulting generation of Factor XIIa activates Factor XI to Factor XIa, which then converts Factor IX to Factor IXa. Factor IXa converts Factor X to Xa. Factor Xa then initiates...","blood coagulation, intrinsic pathway",biological_process
62205,GO:0007598,"A protein activation cascade that initiates blood coagulation, starting with a signal from tissue factor (TF), a cell-surface, integral-membrane protein, which converts Factor IX to IXa, and Factor IXa converts Factor X to Xa. Factor Xa then initiates the common pathway.","blood coagulation, extrinsic pathway",biological_process
62206,GO:0007599,The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.,hemostasis,biological_process
62207,GO:0007600,"The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception,biological_process
62208,GO:0007601,"The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.",visual perception,biological_process
62209,GO:0007602,The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.,phototransduction,biological_process
62210,GO:0007603,"The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.","phototransduction, visible light",biological_process
62211,GO:0007604,The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.,"phototransduction, UV",biological_process
62212,GO:0007605,"The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.",sensory perception of sound,biological_process
62213,GO:0007606,"The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of chemical stimulus,biological_process
62214,GO:0007608,"The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.",sensory perception of smell,biological_process
62215,GO:0007610,"The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.",behavior,biological_process
62216,GO:0007611,The acquisition and processing of information and/or the storage and retrieval of this information over time.,learning or memory,biological_process
62217,GO:0007612,Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.,learning,biological_process
62218,GO:0007613,"The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).",memory,biological_process
62219,GO:0007614,"The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.",short-term memory,biological_process
62220,GO:0007615,"The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.",anesthesia-resistant memory,biological_process
62221,GO:0007616,"The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.",long-term memory,biological_process
62222,GO:0007617,"The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.",mating behavior,biological_process
62223,GO:0007618,"The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.",mating,biological_process
62224,GO:0007619,The behavior of an organism for the purpose of attracting sexual partners.,courtship behavior,biological_process
62225,GO:0007620,"The act of sexual union between male and female, involving the transfer of sperm.",copulation,biological_process
62226,GO:0007621,"Any process that stops, prevents or reduces the receptiveness of a female to male advances.",negative regulation of female receptivity,biological_process
62227,GO:0007622,The specific behavior of an organism that recur with measured regularity.,rhythmic behavior,biological_process
62228,GO:0007623,Any biological process in an organism that recurs with a regularity of approximately 24 hours.,circadian rhythm,biological_process
62229,GO:0007624,The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.,ultradian rhythm,biological_process
62230,GO:0007625,"The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.",grooming behavior,biological_process
62231,GO:0007626,The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.,locomotory behavior,biological_process
62232,GO:0007628,The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.,adult walking behavior,biological_process
62233,GO:0007629,The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.,flight behavior,biological_process
62234,GO:0007630,"The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.",jump response,biological_process
62235,GO:0007631,Behavior associated with the intake of food.,feeding behavior,biological_process
62236,GO:0007632,The behavior of an organism in response to a visual stimulus.,visual behavior,biological_process
62237,GO:0007633,"The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes.",pattern orientation,biological_process
62238,GO:0007634,"The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.",optokinetic behavior,biological_process
62239,GO:0007635,Behavior that is dependent upon the sensation of chemicals.,chemosensory behavior,biological_process
62240,GO:0007636,"The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance.",chemosensory jump behavior,biological_process
62241,GO:0007637,"The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.",proboscis extension reflex,biological_process
62242,GO:0007638,Behavior that is dependent upon the sensation of a mechanical stimulus.,mechanosensory behavior,biological_process
62243,GO:0007639,Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.,homeostasis of number of meristem cells,biological_process
62244,GO:0008009,"The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controllin...",chemokine activity,molecular_function
62245,GO:0008010,The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.,structural constituent of chitin-based larval cuticle,molecular_function
62246,GO:0008011,The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster.,structural constituent of pupal chitin-based cuticle,molecular_function
62247,GO:0008012,The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.,structural constituent of adult chitin-based cuticle,molecular_function
62248,GO:0008013,Binding to a catenin beta subunit.,beta-catenin binding,molecular_function
62249,GO:0008015,"The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.",blood circulation,biological_process
62250,GO:0008016,"Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.",regulation of heart contraction,biological_process
62251,GO:0008017,"Binding to a microtubule, a filament composed of tubulin monomers.",microtubule binding,molecular_function
62252,GO:0008020,"Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.",G protein-coupled photoreceptor activity,molecular_function
62253,GO:0008021,"A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.",synaptic vesicle,cellular_component
62254,GO:0008023,Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.,transcription elongation factor complex,cellular_component
62255,GO:0008024,"A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.",cyclin/CDK positive transcription elongation factor complex,cellular_component
62256,GO:0008028,Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.,monocarboxylic acid transmembrane transporter activity,molecular_function
62257,GO:0008029,Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,pentraxin receptor activity,molecular_function
62258,GO:0008030,Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,neuronal pentraxin receptor activity,molecular_function
62259,GO:0008031,"The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis.",eclosion hormone activity,molecular_function
62260,GO:0008033,"The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.",tRNA processing,biological_process
62261,GO:0008035,"Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.",high-density lipoprotein particle binding,molecular_function
62262,GO:0008036,Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.,diuretic hormone receptor activity,molecular_function
62263,GO:0008037,The process in which a cell in an organism interprets its surroundings.,cell recognition,biological_process
62264,GO:0008038,The process in which a neuronal cell in a multicellular organism interprets its surroundings.,neuron recognition,biological_process
62265,GO:0008039,"The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.",synaptic target recognition,biological_process
62266,GO:0008045,The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.,motor neuron axon guidance,biological_process
62267,GO:0008046,Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.,axon guidance receptor activity,molecular_function
62268,GO:0008047,A molecular function regulator that increases a catalytic activity.,enzyme activator activity,molecular_function
62269,GO:0008048,Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.,calcium sensitive guanylate cyclase activator activity,molecular_function
62270,GO:0008049,"The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.",male courtship behavior,biological_process
62271,GO:0008050,"The behavior of a female, for the purpose of attracting a sexual partner.",female courtship behavior,biological_process
62272,GO:0008052,The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.,sensory organ boundary specification,biological_process
62273,GO:0008053,Merging of two or more mitochondria within a cell to form a single compartment.,mitochondrial fusion,biological_process
62274,GO:0008055,"The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.",ocellus pigment biosynthetic process,biological_process
62275,GO:0008056,"The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.",ocellus development,biological_process
62276,GO:0008057,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.",eye pigment granule organization,biological_process
62277,GO:0008058,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.",ocellus pigment granule organization,biological_process
62278,GO:0008061,"Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.",chitin binding,molecular_function
62279,GO:0008062,"The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.",eclosion rhythm,biological_process
62280,GO:0008063,"The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",Toll signaling pathway,biological_process
62281,GO:0008064,"Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.",regulation of actin polymerization or depolymerization,biological_process
62282,GO:0008065,"The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier.",establishment of blood-nerve barrier,biological_process
62283,GO:0008066,Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,glutamate receptor activity,molecular_function
62284,GO:0008068,Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,extracellularly glutamate-gated chloride channel activity,molecular_function
62285,GO:0008069,Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster.,"dorsal/ventral axis specification, ovarian follicular epithelium",biological_process
62286,GO:0008070,Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line.,"maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded",biological_process
62287,GO:0008071,Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.,"maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded",biological_process
62288,GO:0008073,"Binds to and stops, prevents or reduces the activity of ornithine decarboxylase.",ornithine decarboxylase inhibitor activity,molecular_function
62289,GO:0008074,Complex that possesses guanylate cyclase activity and is not bound to a membrane.,"guanylate cyclase complex, soluble",cellular_component
62290,GO:0008076,A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.,voltage-gated potassium channel complex,cellular_component
62291,GO:0008078,The orderly movement of mesodermal cells from one site to another.,mesodermal cell migration,biological_process
62292,GO:0008079,Functions in the termination of translation.,translation termination factor activity,molecular_function
62293,GO:0008080,Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.,N-acetyltransferase activity,molecular_function
62294,GO:0008081,Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.,phosphoric diester hydrolase activity,molecular_function
62295,GO:0008083,The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.,growth factor activity,molecular_function
62296,GO:0008084,Binding to an imaginal disc growth factor receptor.,imaginal disc growth factor receptor binding,molecular_function
62297,GO:0008086,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,light-activated voltage-gated calcium channel activity,molecular_function
62298,GO:0008087,A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.,light-activated voltage-gated calcium channel complex,cellular_component
62299,GO:0008088,The directed movement of organelles or molecules along microtubules in neuron projections.,axo-dendritic transport,biological_process
62300,GO:0008089,The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.,anterograde axonal transport,biological_process
62301,GO:0008090,The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.,retrograde axonal transport,biological_process
62302,GO:0008091,"Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.",spectrin,cellular_component
62303,GO:0008092,"Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).",cytoskeletal protein binding,molecular_function
62304,GO:0008093,"The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way.",cytoskeletal adaptor activity,molecular_function
62305,GO:0008094,"Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.","ATP-dependent activity, acting on DNA",molecular_function
62306,GO:0008096,Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.,juvenile hormone epoxide hydrolase activity,molecular_function
62307,GO:0008097,"Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.",5S rRNA binding,molecular_function
62308,GO:0008098,Binding to an unprocessed 5S ribosomal RNA transcript.,5S rRNA primary transcript binding,molecular_function
62309,GO:0008103,"Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.",oocyte microtubule cytoskeleton polarization,biological_process
62310,GO:0008104,"Any process in which a protein is transported to, or maintained in, a specific location.",intracellular protein localization,biological_process
62311,GO:0008106,Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or ketone + NADPH + H+.,alcohol dehydrogenase (NADP+) activity,molecular_function
62312,GO:0008107,"Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.",galactoside 2-alpha-L-fucosyltransferase activity,molecular_function
62313,GO:0008108,Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.,UDP-glucose:hexose-1-phosphate uridylyltransferase activity,molecular_function
62314,GO:0008109,"Catalysis of the reaction: a beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl derivative + UDP + H+.","N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity",molecular_function
62315,GO:0008110,Catalysis of the reaction: L-histidine + 2-oxoglutarate = 3-(imidazol-5-yl)pyruvate + L-glutamate.,L-histidine:2-oxoglutarate transaminase activity,molecular_function
62316,GO:0008111,Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.,alpha-methylacyl-CoA racemase activity,molecular_function
62317,GO:0008112,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.,nicotinamide N-methyltransferase activity,molecular_function
62318,GO:0008113,Catalysis of the reaction: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol.,peptide-methionine (S)-S-oxide reductase activity,molecular_function
62319,GO:0008114,Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.,phosphogluconate 2-dehydrogenase activity,molecular_function
62320,GO:0008115,Catalysis of the reaction: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2.,sarcosine oxidase activity,molecular_function
62321,GO:0008116,Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).,prostaglandin-I synthase activity,molecular_function
62322,GO:0008117,Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.,sphinganine-1-phosphate aldolase activity,molecular_function
62323,GO:0008118,Catalysis of the reaction: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H+.,"N-acetyllactosaminide alpha-2,3-sialyltransferase activity",molecular_function
62324,GO:0008119,Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.,thiopurine S-methyltransferase activity,molecular_function
62325,GO:0008120,Catalysis of the reaction: an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP.,ceramide glucosyltransferase activity,molecular_function
62326,GO:0008121,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: a quinol + 2 Fe(III)-cytochrome c = a quinone + 2 Fe(II)-cytochrome c + 2 H+(out).,quinol-cytochrome-c reductase activity,molecular_function
62327,GO:0008123,Catalysis of the reaction: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha-hydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,cholesterol 7-alpha-monooxygenase activity,molecular_function
62328,GO:0008124,"Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.",4-alpha-hydroxytetrahydrobiopterin dehydratase activity,molecular_function
62329,GO:0008126,Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.,acetylesterase activity,molecular_function
62330,GO:0008127,"Catalysis of the reaction: H+ + O2 + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.","quercetin 2,3-dioxygenase activity",molecular_function
62331,GO:0008131,Catalysis of the reaction: a primary methyl amine + H2O + O2 = an aldehyde + H2O2 + NH4+.,primary methylamine oxidase activity,molecular_function
62332,GO:0008134,"Binding to a transcription factor, a protein required to initiate or regulate transcription.",transcription factor binding,molecular_function
62333,GO:0008135,Functions during translation by binding to RNA during polypeptide synthesis at the ribosome.,"translation factor activity, RNA binding",molecular_function
62334,GO:0008137,Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) = NAD+ + ubiquinol + 4 H+(out).,NADH dehydrogenase (ubiquinone) activity,molecular_function
62335,GO:0008138,Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.,protein tyrosine/serine/threonine phosphatase activity,molecular_function
62336,GO:0008140,Binding to a cAMP response element binding protein (a CREB protein).,cAMP response element binding protein binding,molecular_function
62337,GO:0008142,"Binding to oxysterol, an oxidized form of cholesterol.",oxysterol binding,molecular_function
62338,GO:0008143,"Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.",poly(A) binding,molecular_function
62339,GO:0008145,Binding to phenylalkylamine or one of its derivatives.,phenylalkylamine binding,molecular_function
62340,GO:0008146,"Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.",sulfotransferase activity,molecular_function
62341,GO:0008147,The action of a molecule that contributes to the structural integrity of bone.,structural constituent of bone,molecular_function
62342,GO:0008150,"A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.",biological_process,biological_process
62343,GO:0008152,"A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well  macromolecular processes such as DNA repair and replication, protein synthesis and degradation.",metabolic process,biological_process
62344,GO:0008153,"The chemical reactions and pathways resulting in the formation of 4-aminobenzoate, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.",4-aminobenzoate biosynthetic process,biological_process
62345,GO:0008154,Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.,actin polymerization or depolymerization,biological_process
62346,GO:0008156,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.",negative regulation of DNA replication,biological_process
62347,GO:0008157,Binding to a protein phosphatase 1.,protein phosphatase 1 binding,molecular_function
62348,GO:0008158,Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.,hedgehog receptor activity,molecular_function
62349,GO:0008160,"Binds to and increases the activity of a phosphotyrosine phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.",protein tyrosine phosphatase activator activity,molecular_function
62350,GO:0008168,Catalysis of the transfer of a methyl group to an acceptor molecule.,methyltransferase activity,molecular_function
62351,GO:0008169,Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.,C-methyltransferase activity,molecular_function
62352,GO:0008170,Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.,N-methyltransferase activity,molecular_function
62353,GO:0008171,Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.,O-methyltransferase activity,molecular_function
62354,GO:0008172,Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.,S-methyltransferase activity,molecular_function
62355,GO:0008173,Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.,RNA methyltransferase activity,molecular_function
62356,GO:0008174,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.,mRNA methyltransferase activity,molecular_function
62357,GO:0008175,Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. The methyl group can be transfered to the nucleobase or to the ribose group of the nucleoside.,tRNA methyltransferase activity,molecular_function
62358,GO:0008176,Catalysis of the reaction: guanosine46 in tRNA + S-adenosyl-L-methionine = N7-methylguanosine46 in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanine(46)-N7)-methyltransferase activity,molecular_function
62359,GO:0008177,Catalysis of the reaction: a quinone + succinate = a quinol + fumarate.,succinate dehydrogenase (quinone) activity,molecular_function
62360,GO:0008179,Binding to an adenylate cyclase.,adenylate cyclase binding,molecular_function
62361,GO:0008180,"A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.",COP9 signalosome,cellular_component
62362,GO:0008184,Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.,glycogen phosphorylase activity,molecular_function
62363,GO:0008186,"Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.","ATP-dependent activity, acting on RNA",molecular_function
62364,GO:0008187,Binding to a stretch of pyrimidines (cytosine or uracil) in an RNA molecule.,poly-pyrimidine tract binding,molecular_function
62365,GO:0008188,Combining with a neuropeptide to initiate a change in cell activity.,neuropeptide receptor activity,molecular_function
62366,GO:0008190,"Binding to eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.",eukaryotic initiation factor 4E binding,molecular_function
62367,GO:0008191,"Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.",metalloendopeptidase inhibitor activity,molecular_function
62368,GO:0008192,Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.,RNA guanylyltransferase activity,molecular_function
62369,GO:0008193,Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.,tRNA guanylyltransferase activity,molecular_function
62370,GO:0008194,Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.,UDP-glycosyltransferase activity,molecular_function
62371,GO:0008195,"Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.",phosphatidate phosphatase activity,molecular_function
62372,GO:0008196,"Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.",vitellogenin receptor activity,molecular_function
62373,GO:0008198,"Binding to a ferrous iron ion, Fe(II).",ferrous iron binding,molecular_function
62374,GO:0008199,"Binding to a ferric iron ion, Fe(III).",ferric iron binding,molecular_function
62375,GO:0008200,"Binds to and stops, prevents, or reduces the activity of an ion channel.",ion channel inhibitor activity,molecular_function
62376,GO:0008201,"Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.",heparin binding,molecular_function
62377,GO:0008202,"The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.",steroid metabolic process,biological_process
62378,GO:0008203,"The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.",cholesterol metabolic process,biological_process
62379,GO:0008204,"The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.",ergosterol metabolic process,biological_process
62380,GO:0008205,"The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.",ecdysone metabolic process,biological_process
62381,GO:0008206,"The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.",bile acid metabolic process,biological_process
62382,GO:0008207,"The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.",C21-steroid hormone metabolic process,biological_process
62383,GO:0008208,"The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.",C21-steroid hormone catabolic process,biological_process
62384,GO:0008209,"The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.",androgen metabolic process,biological_process
62385,GO:0008210,"The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.",estrogen metabolic process,biological_process
62386,GO:0008211,"The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.",glucocorticoid metabolic process,biological_process
62387,GO:0008212,"The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.",mineralocorticoid metabolic process,biological_process
62388,GO:0008213,The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.,protein alkylation,biological_process
62389,GO:0008214,The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.,protein dealkylation,biological_process
62390,GO:0008215,"The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.",spermine metabolic process,biological_process
62391,GO:0008216,"The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",spermidine metabolic process,biological_process
62392,GO:0008217,Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.,regulation of blood pressure,biological_process
62393,GO:0008218,The production of light by certain enzyme-catalyzed reactions in cells.,bioluminescence,biological_process
62394,GO:0008219,"Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment o...",cell death,biological_process
62395,GO:0008226,Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.,tyramine receptor activity,molecular_function
62396,GO:0008227,Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled amine receptor activity,molecular_function
62397,GO:0008228,"The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.",opsonization,biological_process
62398,GO:0008230,"A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.",ecdysone receptor holocomplex,cellular_component
62399,GO:0008231,"A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.",repressor ecdysone receptor complex,cellular_component
62400,GO:0008232,"A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.",activator ecdysone receptor complex,cellular_component
62401,GO:0008233,Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.,peptidase activity,molecular_function
62402,GO:0008234,Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.,cysteine-type peptidase activity,molecular_function
62403,GO:0008235,"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metalloexopeptidase activity,molecular_function
62404,GO:0008236,Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).,serine-type peptidase activity,molecular_function
62405,GO:0008237,"Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metallopeptidase activity,molecular_function
62406,GO:0008238,"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.",exopeptidase activity,molecular_function
62407,GO:0008239,Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.,dipeptidyl-peptidase activity,molecular_function
62408,GO:0008240,Catalysis of the release of an N-terminal tripeptide from a polypeptide.,tripeptidyl-peptidase activity,molecular_function
62409,GO:0008241,Catalysis of the release of C-terminal dipeptides from a polypeptide chain.,peptidyl-dipeptidase activity,molecular_function
62410,GO:0008242,"Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.",omega peptidase activity,molecular_function
62411,GO:0008247,"An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF).",1-alkyl-2-acetylglycerophosphocholine esterase complex,cellular_component
62412,GO:0008250,A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. The complex includes at least eight non-identical subunits. Different forms of the complex containing distinct subunits have been detected in mammals.,oligosaccharyltransferase complex,cellular_component
62413,GO:0008251,"Catalysis of the reaction: adenosine + H2O = inosine + NH4+, in a tRNA molecule.",tRNA-specific adenosine deaminase activity,molecular_function
62414,GO:0008252,Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.,nucleotidase activity,molecular_function
62415,GO:0008253,Catalysis of the reaction: a nucleoside 5'-phosphate + H2O = a nucleoside + phosphate.,5'-nucleotidase activity,molecular_function
62416,GO:0008254,Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.,3'-nucleotidase activity,molecular_function
62417,GO:0008255,"The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.",ecdysis-triggering hormone activity,molecular_function
62418,GO:0008256,Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.,protein histidine pros-kinase activity,molecular_function
62419,GO:0008257,Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.,protein histidine tele-kinase activity,molecular_function
62420,GO:0008258,Movement of the anterior ectoderm to the interior of the embryo.,head involution,biological_process
62421,GO:0008260,Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA.,succinyl-CoA:3-oxo-acid CoA-transferase activity,molecular_function
62422,GO:0008261,Combining with allatostatin to initiate a change in cell activity.,allatostatin receptor activity,molecular_function
62423,GO:0008263,Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.,pyrimidine-specific mismatch base pair DNA N-glycosylase activity,molecular_function
62424,GO:0008265,Catalysis of the reaction: AH2 + L-cysteine + Mo-molybdopterin = A + H2O + L-alanine + thio-Mo-molybdopterin.,molybdenum cofactor sulfurtransferase activity,molecular_function
62425,GO:0008266,Binding to a sequence of uracil residues in an RNA molecule.,poly(U) RNA binding,molecular_function
62426,GO:0008267,"Binding to a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.",poly-glutamine tract binding,molecular_function
62427,GO:0008269,"The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way.",JAK pathway signal transduction adaptor activity,molecular_function
62428,GO:0008270,Binding to a zinc ion (Zn).,zinc ion binding,molecular_function
62429,GO:0008271,"Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",secondary active sulfate transmembrane transporter activity,molecular_function
62430,GO:0008273,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).,"calcium, potassium:sodium antiporter activity",molecular_function
62431,GO:0008275,A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.,gamma-tubulin small complex,cellular_component
62432,GO:0008276,Catalysis of the transfer of a methyl group (CH3-) to a protein.,protein methyltransferase activity,molecular_function
62433,GO:0008277,"Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.",regulation of G protein-coupled receptor signaling pathway,biological_process
62434,GO:0008278,"A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which...",cohesin complex,cellular_component
62435,GO:0008281,"Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",sulfonylurea receptor activity,molecular_function
62436,GO:0008282,"A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.",inward rectifying potassium channel,cellular_component
62437,GO:0008283,"The multiplication or reproduction of cells, resulting in the expansion of a cell population.",cell population proliferation,biological_process
62438,GO:0008284,Any process that activates or increases the rate or extent of cell proliferation.,positive regulation of cell population proliferation,biological_process
62439,GO:0008285,"Any process that stops, prevents or reduces the rate or extent of cell proliferation.",negative regulation of cell population proliferation,biological_process
62440,GO:0008286,The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.,insulin receptor signaling pathway,biological_process
62441,GO:0008287,"A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.",protein serine/threonine phosphatase complex,cellular_component
62442,GO:0008288,Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.,boss receptor activity,molecular_function
62443,GO:0008289,Binding to a lipid.,lipid binding,molecular_function
62444,GO:0008290,"A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.",F-actin capping protein complex,cellular_component
62445,GO:0008291,"The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.",acetylcholine metabolic process,biological_process
62446,GO:0008292,"The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.",acetylcholine biosynthetic process,biological_process
62447,GO:0008293,"The series of molecular signals initiated by an extracellular ligand binding to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",torso signaling pathway,biological_process
62448,GO:0008294,"Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.",calcium- and calmodulin-responsive adenylate cyclase activity,molecular_function
62449,GO:0008295,"The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",spermidine biosynthetic process,biological_process
62450,GO:0008296,Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.,3'-5'-DNA exonuclease activity,molecular_function
62451,GO:0008297,Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule.,single-stranded DNA exodeoxyribonuclease activity,molecular_function
62452,GO:0008298,"Any process in which mRNA is transported to, or maintained in, a specific location within the cell.",intracellular mRNA localization,biological_process
62453,GO:0008299,"The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.",isoprenoid biosynthetic process,biological_process
62454,GO:0008300,"The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.",isoprenoid catabolic process,biological_process
62455,GO:0008301,"The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.","DNA binding, bending",molecular_function
62456,GO:0008302,Recruitment and organization of actin filaments in female germline ring canals.,"female germline ring canal formation, actin assembly",biological_process
62457,GO:0008303,"A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.",caspase complex,cellular_component
62458,GO:0008305,"A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.",integrin complex,cellular_component
62459,GO:0008306,Learning by associating a stimulus (the cause) with a particular outcome (the effect).,associative learning,biological_process
62460,GO:0008307,The action of a molecule that contributes to the structural integrity of a muscle fiber.,structural constituent of muscle,molecular_function
62461,GO:0008308,Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated monoatomic anion channel activity,molecular_function
62462,GO:0008309,Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.,double-stranded DNA exodeoxyribonuclease activity,molecular_function
62463,GO:0008310,Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.,single-stranded DNA 3'-5' DNA exonuclease activity,molecular_function
62464,GO:0008311,Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.,double-stranded DNA 3'-5' DNA exonuclease activity,molecular_function
62465,GO:0008312,"Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).",7S RNA binding,molecular_function
62466,GO:0008315,The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I.,G2/MI transition of meiotic cell cycle,biological_process
62467,GO:0008316,The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster.,structural constituent of vitelline membrane,molecular_function
62468,GO:0008318,Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.,protein prenyltransferase activity,molecular_function
62469,GO:0008320,Enables the transfer of a protein from one side of a membrane to the other.,transmembrane protein transporter activity,molecular_function
62470,GO:0008324,Enables the transfer of cation from one side of a membrane to the other.,monoatomic cation transmembrane transporter activity,molecular_function
62471,GO:0008327,Binding to a methylated cytosine/guanine dinucleotide.,methyl-CpG binding,molecular_function
62472,GO:0008328,"A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.",ionotropic glutamate receptor complex,cellular_component
62473,GO:0008330,Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.,protein tyrosine/threonine phosphatase activity,molecular_function
62474,GO:0008331,Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.,high voltage-gated calcium channel activity,molecular_function
62475,GO:0008332,Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.,low voltage-gated calcium channel activity,molecular_function
62476,GO:0008333,The directed movement of substances from endosomes to lysosomes.,endosome to lysosome transport,biological_process
62477,GO:0008334,The chemical reactions and pathways involving an mRNA encoding a histone.,histone mRNA metabolic process,biological_process
62478,GO:0008335,Maintenance of the structural integrity of the ring canals connecting the female germline cyst.,female germline ring canal stabilization,biological_process
62479,GO:0008336,Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O2 = carnitine + CO2 + succinate.,gamma-butyrobetaine dioxygenase activity,molecular_function
62480,GO:0008340,The pathways that regulate the duration of the adult phase of the life-cycle of an animal.,determination of adult lifespan,biological_process
62481,GO:0008343,Feeding behavior in a fully developed and mature organism.,adult feeding behavior,biological_process
62482,GO:0008344,Locomotory behavior in a fully developed and mature organism.,adult locomotory behavior,biological_process
62483,GO:0008345,Locomotory behavior in a larval (immature) organism.,larval locomotory behavior,biological_process
62484,GO:0008346,The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.,larval walking behavior,biological_process
62485,GO:0008347,"The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.",glial cell migration,biological_process
62486,GO:0008348,"Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.",negative regulation of antimicrobial humoral response,biological_process
62487,GO:0008349,"Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.",MAP kinase kinase kinase kinase activity,molecular_function
62488,GO:0008352,A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).,katanin complex,cellular_component
62489,GO:0008353,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.,RNA polymerase II CTD heptapeptide repeat kinase activity,molecular_function
62490,GO:0008354,The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.,primordial germ cell migration,biological_process
62491,GO:0008355,Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.,olfactory learning,biological_process
62492,GO:0008356,The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.,asymmetric cell division,biological_process
62493,GO:0008358,"The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.","maternal determination of anterior/posterior axis, embryo",biological_process
62494,GO:0008359,"Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.",regulation of bicoid mRNA localization,biological_process
62495,GO:0008360,Any process that modulates the surface configuration of a cell.,regulation of cell shape,biological_process
62496,GO:0008361,Any process that modulates the size of a cell.,regulation of cell size,biological_process
62497,GO:0008362,"Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.",chitin-based embryonic cuticle biosynthetic process,biological_process
62498,GO:0008363,Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.,larval chitin-based cuticle development,biological_process
62499,GO:0008364,Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster.,pupal chitin-based cuticle development,biological_process
62500,GO:0008365,"Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.",adult chitin-based cuticle development,biological_process
62501,GO:0008366,"Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.",axon ensheathment,biological_process
62502,GO:0008373,"Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.",sialyltransferase activity,molecular_function
62503,GO:0008375,Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.,acetylglucosaminyltransferase activity,molecular_function
62504,GO:0008376,Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.,acetylgalactosaminyltransferase activity,molecular_function
62505,GO:0008378,"Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",galactosyltransferase activity,molecular_function
62506,GO:0008379,Catalysis of the reaction: [thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + H2O.,thioredoxin peroxidase activity,molecular_function
62507,GO:0008380,The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.,RNA splicing,biological_process
62508,GO:0008381,Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress.,mechanosensitive monoatomic ion channel activity,molecular_function
62509,GO:0008384,Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.,IkappaB kinase activity,molecular_function
62510,GO:0008385,"A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA a...",IkappaB kinase complex,cellular_component
62511,GO:0008386,Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.,cholesterol monooxygenase (side-chain-cleaving) activity,molecular_function
62512,GO:0008387,Catalysis of the reaction: a steroid + AH2 + O2 = 7-alpha-hydroxysteroid + H2O.,steroid 7-alpha-hydroxylase activity,molecular_function
62513,GO:0008388,Catalysis of the reaction: reduced [NADPH-hemoprotein reductase] + O2 + a steroid = oxidized [NADPH-hemoprotein reductase] + H2O + H+ + 15alpha-hydroxy steroid.,steroid 15-alpha-hydroxylase activity,molecular_function
62514,GO:0008389,Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.,coumarin 7-hydroxylase activity,molecular_function
62515,GO:0008390,"Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16alpha,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",testosterone 16-alpha-hydroxylase activity,molecular_function
62516,GO:0008391,Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.,arachidonate monooxygenase activity,molecular_function
62517,GO:0008392,Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.,arachidonate epoxygenase activity,molecular_function
62518,GO:0008395,Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.,steroid hydroxylase activity,molecular_function
62519,GO:0008396,Catalysis of the reaction: 7-oxocholesterol + H+ + NADPH = 7alpha-hydroxycholesterol + NADP+.,oxysterol 7-alpha-hydroxylase activity,molecular_function
62520,GO:0008397,Catalysis of the reaction: a steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-alpha-hydroxysteroid + oxidized [NADPH--hemoprotein reductase]- H2O +H+.,sterol 12-alpha-hydroxylase activity,molecular_function
62521,GO:0008398,Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].,sterol 14-demethylase activity,molecular_function
62522,GO:0008401,Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.,retinoic acid 4-hydroxylase activity,molecular_function
62523,GO:0008403,"Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.",25-hydroxycholecalciferol-24-hydroxylase activity,molecular_function
62524,GO:0008404,"Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid.","arachidonate 14,15-epoxygenase activity",molecular_function
62525,GO:0008405,"Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.","arachidonate 11,12-epoxygenase activity",molecular_function
62526,GO:0008406,"The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.",gonad development,biological_process
62527,GO:0008407,The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.,chaeta morphogenesis,biological_process
62528,GO:0008408,Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.,3'-5' exonuclease activity,molecular_function
62529,GO:0008409,Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.,5'-3' exonuclease activity,molecular_function
62530,GO:0008410,Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor).,CoA-transferase activity,molecular_function
62531,GO:0008412,Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate.,4-hydroxybenzoate polyprenyltransferase activity,molecular_function
62532,GO:0008413,"Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.","8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity",molecular_function
62533,GO:0008417,"Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",fucosyltransferase activity,molecular_function
62534,GO:0008418,Catalysis of the reaction: N-terminal L-asparaginyl-[protein] + H+ + H2O = N-terminal L-aspartyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.,protein-N-terminal asparagine amidohydrolase activity,molecular_function
62535,GO:0008419,Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.,RNA lariat debranching enzyme activity,molecular_function
62536,GO:0008420,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine/threonine (consensus YSPTSPS) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat phosphatase activity,molecular_function
62537,GO:0008421,Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.,long-chain fatty-acyl-glutamate deacylase activity,molecular_function
62538,GO:0008422,"Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.",beta-glucosidase activity,molecular_function
62539,GO:0008424,Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-be...,glycoprotein 6-alpha-L-fucosyltransferase activity,molecular_function
62540,GO:0008425,"Catalysis of the reaction: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+.","2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity",molecular_function
62541,GO:0008426,"Binds to and stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein.",protein kinase C inhibitor activity,molecular_function
62542,GO:0008427,"Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase.",calcium-dependent protein kinase inhibitor activity,molecular_function
62543,GO:0008428,"Binds to and stops, prevents or reduces the activity of ribonuclease.",ribonuclease inhibitor activity,molecular_function
62544,GO:0008429,"Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.",phosphatidylethanolamine binding,molecular_function
62545,GO:0008430,Binding to a selenium (Se) ion.,selenium binding,molecular_function
62546,GO:0008431,"Binding to a vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.",vitamin E binding,molecular_function
62547,GO:0008432,"Binding to JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.",JUN kinase binding,molecular_function
62548,GO:0008437,"The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.",thyrotropin-releasing hormone activity,molecular_function
62549,GO:0008440,"Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H+.","inositol-1,4,5-trisphosphate 3-kinase activity",molecular_function
62550,GO:0008441,"Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.","3'(2'),5'-bisphosphate nucleotidase activity",molecular_function
62551,GO:0008442,Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.,3-hydroxyisobutyrate dehydrogenase activity,molecular_function
62552,GO:0008443,"Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule.",phosphofructokinase activity,molecular_function
62553,GO:0008444,Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H+.,CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity,molecular_function
62554,GO:0008445,Catalysis of the reaction: D-aspartate + H2O + O2 = H2O2 + NH4+ + oxaloacetate.,D-aspartate oxidase activity,molecular_function
62555,GO:0008446,Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O.,"GDP-mannose 4,6-dehydratase activity",molecular_function
62556,GO:0008447,Catalysis of the reaction: 4 L-ascorbate + O2 = 4 monodehydroascorbate + 2 H2O.,L-ascorbate oxidase activity,molecular_function
62557,GO:0008448,Catalysis of the reaction: H2O + N-acetyl-D-glucosamine 6-phosphate = acetate + D-glucosamine 6-phosphate.,N-acetylglucosamine-6-phosphate deacetylase activity,molecular_function
62558,GO:0008449,Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.,N-acetylglucosamine-6-sulfatase activity,molecular_function
62559,GO:0008452,Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the phosphate group at the end of another.,RNA ligase activity,molecular_function
62560,GO:0008453,Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.,L-alanine:glyoxylate transaminase activity,molecular_function
62561,GO:0008454,"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.","alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",molecular_function
62562,GO:0008455,"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.","alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity",molecular_function
62563,GO:0008456,Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.,alpha-N-acetylgalactosaminidase activity,molecular_function
62564,GO:0008458,Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = CoA + O-octanoyl-(R)-carnitine.,carnitine O-octanoyltransferase activity,molecular_function
62565,GO:0008459,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.",chondroitin 6-sulfotransferase activity,molecular_function
62566,GO:0008460,Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.,"dTDP-glucose 4,6-dehydratase activity",molecular_function
62567,GO:0008463,Catalysis of the reaction: N-formyl-L-methionine + H2O = L-methionine + formate.,formylmethionine deformylase activity,molecular_function
62568,GO:0008465,Catalysis of the reaction: (R)-glycerate + NAD+ = 3-hydroxypyruvate + NADH + H+.,hydroxypyruvate reductase (NADH) activity,molecular_function
62569,GO:0008466,"Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin. This first reaction is a self glucosylation. Further UDP-glucose goups are added to the [1,4-alpha-D-glucosyl](n) group of glycogenin until a length of about 5-13 residues.",glycogenin glucosyltransferase activity,molecular_function
62570,GO:0008467,"Catalysis of the reaction: alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H+.",[heparan sulfate]-glucosamine 3-sulfotransferase activity,molecular_function
62571,GO:0008470,Catalysis of the reaction: 3-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein].,3-methylbutanoyl-CoA dehydrogenase activity,molecular_function
62572,GO:0008473,Catalysis of the reaction: L-ornithine = L-proline + NH4.,ornithine cyclodeaminase activity,molecular_function
62573,GO:0008474,Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.,palmitoyl-(protein) hydrolase activity,molecular_function
62574,GO:0008475,Catalysis of the reaction: L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2.,procollagen-lysine 5-dioxygenase activity,molecular_function
62575,GO:0008476,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.",protein-tyrosine sulfotransferase activity,molecular_function
62576,GO:0008477,Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.,purine nucleosidase activity,molecular_function
62577,GO:0008478,Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.,pyridoxal kinase activity,molecular_function
62578,GO:0008479,Catalysis of the reaction: guanosine34 in tRNA + queuine = guanine + queuosine34 in tRNA.,tRNA-guanosine(34) queuine transglycosylase activity,molecular_function
62579,GO:0008480,Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.,sarcosine dehydrogenase activity,molecular_function
62580,GO:0008481,Catalysis of the reaction: a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H+.,sphingosine kinase activity,molecular_function
62581,GO:0008482,Catalysis of the reaction: H2O + O2 + sulfite = H2O2 + H+ + sulfate.,sulfite oxidase activity,molecular_function
62582,GO:0008483,"Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.",transaminase activity,molecular_function
62583,GO:0008484,"Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2.",sulfuric ester hydrolase activity,molecular_function
62584,GO:0008486,Catalysis of the reaction: diphospho-1D-myo-inositol polyphosphate + H2O = 1D-myo-inositol polyphosphate + phosphate.,diphosphoinositol-polyphosphate diphosphatase activity,molecular_function
62585,GO:0008488,Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide.,gamma-glutamyl carboxylase activity,molecular_function
62586,GO:0008489,Catalysis of the reaction: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H+ + UDP.,"UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity",molecular_function
62587,GO:0008490,"Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",arsenite secondary active transmembrane transporter activity,molecular_function
62588,GO:0008493,Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).,tetracycline transmembrane transporter activity,molecular_function
62589,GO:0008494,Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.,translation activator activity,molecular_function
62590,GO:0008495,"Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.",protoheme IX farnesyltransferase activity,molecular_function
62591,GO:0008496,Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.,"mannan endo-1,6-alpha-mannosidase activity",molecular_function
62592,GO:0008499,Catalysis of the reaction: an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H+ + UDP.,"N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity",molecular_function
62593,GO:0008502,"Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.",melatonin receptor activity,molecular_function
62594,GO:0008503,"Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.",benzodiazepine receptor activity,molecular_function
62595,GO:0008504,"Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.",monoamine transmembrane transporter activity,molecular_function
62596,GO:0008506,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).,sucrose:proton symporter activity,molecular_function
62597,GO:0008507,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).,sodium:iodide symporter activity,molecular_function
62598,GO:0008508,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).,bile acid:sodium symporter activity,molecular_function
62599,GO:0008509,Enables the transfer of a negatively charged ion from one side of a membrane to the other.,monoatomic anion transmembrane transporter activity,molecular_function
62600,GO:0008510,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).,sodium:bicarbonate symporter activity,molecular_function
62601,GO:0008511,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).,sodium:potassium:chloride symporter activity,molecular_function
62602,GO:0008512,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in).,sulfate:proton symporter activity,molecular_function
62603,GO:0008515,"Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.",sucrose transmembrane transporter activity,molecular_function
62604,GO:0008516,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in).,hexose uniporter activity,molecular_function
62605,GO:0008517,Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.,folic acid transmembrane transporter activity,molecular_function
62606,GO:0008518,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.",folate:monoatomic anion antiporter activity,molecular_function
62607,GO:0008519,Enables the energy-independent facilitated diffusion of ammonium through a transmembrane aqueous pore or channel.,ammonium channel activity,molecular_function
62608,GO:0008520,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).,L-ascorbate:sodium symporter activity,molecular_function
62609,GO:0008521,"Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.",acetyl-CoA transmembrane transporter activity,molecular_function
62610,GO:0008523,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate.",sodium-dependent multivitamin transmembrane transporter activity,molecular_function
62611,GO:0008525,Enables the transport of phosphatidylcholine from a region of a membrane to a different region on the same membrane.,phosphatidylcholine intramembrane carrier activity,molecular_function
62612,GO:0008526,"Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",phosphatidylinositol transfer activity,molecular_function
62613,GO:0008527,Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.,taste receptor activity,molecular_function
62614,GO:0008528,Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled peptide receptor activity,molecular_function
62615,GO:0008531,Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.,riboflavin kinase activity,molecular_function
62616,GO:0008532,Catalysis of the reaction: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H+ + UDP.,"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity",molecular_function
62617,GO:0008534,"Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.",oxidized purine nucleobase lesion DNA N-glycosylase activity,molecular_function
62618,GO:0008535,"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.",respiratory chain complex IV assembly,biological_process
62619,GO:0008537,A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.,proteasome activator complex,cellular_component
62620,GO:0008540,The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex.,"proteasome regulatory particle, base subcomplex",cellular_component
62621,GO:0008541,"The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.","proteasome regulatory particle, lid subcomplex",cellular_component
62622,GO:0008542,Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.,visual learning,biological_process
62623,GO:0008543,The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.,fibroblast growth factor receptor signaling pathway,biological_process
62624,GO:0008544,"The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.",epidermis development,biological_process
62625,GO:0008545,"Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.",JUN kinase kinase activity,molecular_function
62626,GO:0008551,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) = ADP + phosphate + Cd2+(out).,P-type cadmium transporter activity,molecular_function
62627,GO:0008553,"Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.",P-type proton-exporting transporter activity,molecular_function
62628,GO:0008554,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.,P-type sodium transporter activity,molecular_function
62629,GO:0008556,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in).,P-type potassium transmembrane transporter activity,molecular_function
62630,GO:0008558,Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).,ABC-type guanine transporter activity,molecular_function
62631,GO:0008559,Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).,ABC-type xenobiotic transporter activity,molecular_function
62632,GO:0008564,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) = ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.,protein-exporting ATPase activity,molecular_function
62633,GO:0008566,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.,mitochondrial protein-transporting ATPase activity,molecular_function
62634,GO:0008568,"Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.",microtubule severing ATPase activity,molecular_function
62635,GO:0008569,"A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.",minus-end-directed microtubule motor activity,molecular_function
62636,GO:0008574,"A motor activity that generates movement along a microtubule toward the plus end, driven by ATP hydrolysis.",plus-end-directed microtubule motor activity,molecular_function
62637,GO:0008579,Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.,JUN kinase phosphatase activity,molecular_function
62638,GO:0008582,"Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions.",regulation of synaptic assembly at neuromuscular junction,biological_process
62639,GO:0008583,"The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.",mystery cell differentiation,biological_process
62640,GO:0008584,"The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.",male gonad development,biological_process
62641,GO:0008585,"The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.",female gonad development,biological_process
62642,GO:0008586,The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.,imaginal disc-derived wing vein morphogenesis,biological_process
62643,GO:0008587,The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.,imaginal disc-derived wing margin morphogenesis,biological_process
62644,GO:0008589,"Any process that modulates the frequency, rate or extent of smoothened signaling.",regulation of smoothened signaling pathway,biological_process
62645,GO:0008591,"Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).","regulation of Wnt signaling pathway, calcium modulating pathway",biological_process
62646,GO:0008592,"Any process that modulates the frequency, rate or extent of the Tl signaling pathway.",regulation of Toll signaling pathway,biological_process
62647,GO:0008593,"Any process that modulates the frequency, rate or extent of the Notch signaling pathway.",regulation of Notch signaling pathway,biological_process
62648,GO:0008594,"The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.",photoreceptor cell morphogenesis,biological_process
62649,GO:0008595,The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.,"anterior/posterior axis specification, embryo",biological_process
62650,GO:0008597,Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.,calcium-dependent protein serine/threonine phosphatase regulator activity,molecular_function
62651,GO:0008603,Modulation of the activity of the enzyme cAMP-dependent protein kinase.,cAMP-dependent protein kinase regulator activity,molecular_function
62652,GO:0008607,Modulation of the activity of the enzyme phosphorylase kinase.,phosphorylase kinase regulator activity,molecular_function
62653,GO:0008608,The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.,attachment of spindle microtubules to kinetochore,biological_process
62654,GO:0008609,Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.,alkylglycerone-phosphate synthase activity,molecular_function
62655,GO:0008610,"The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.",lipid biosynthetic process,biological_process
62656,GO:0008611,"The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.",ether lipid biosynthetic process,biological_process
62657,GO:0008612,"The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine, an unusual amino acid synthesized post-translationally.",peptidyl-hypusine biosynthetic process,biological_process
62658,GO:0008613,"The action characteristic of a diuretic hormone, a peptide hormone that, upon receptor binding, regulates water balance and fluid secretion.",diuretic hormone activity,molecular_function
62659,GO:0008614,"The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxine metabolic process,biological_process
62660,GO:0008615,"The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.",pyridoxine biosynthetic process,biological_process
62661,GO:0008616,"The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in position 34 of tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.",tRNA queuosine(34) biosynthetic process,biological_process
62662,GO:0008617,"The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.",guanosine metabolic process,biological_process
62663,GO:0008618,"The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.",7-methylguanosine metabolic process,biological_process
62664,GO:0008622,"A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.",epsilon DNA polymerase complex,cellular_component
62665,GO:0008623,"An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.",CHRAC,cellular_component
62666,GO:0008625,"The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.",extrinsic apoptotic signaling pathway via death domain receptors,biological_process
62667,GO:0008626,"The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.",granzyme-mediated apoptotic signaling pathway,biological_process
62668,GO:0008627,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to osmotic stress,biological_process
62669,GO:0008628,"The series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.",hormone-mediated apoptotic signaling pathway,biological_process
62670,GO:0008630,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to DNA damage,biological_process
62671,GO:0008631,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to oxidative stress,biological_process
62672,GO:0008637,The morphological and physiological alterations undergone by mitochondria during apoptosis.,apoptotic mitochondrial changes,biological_process
62673,GO:0008641,"Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.",ubiquitin-like modifier activating enzyme activity,molecular_function
62674,GO:0008643,"The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate transport,biological_process
62675,GO:0008645,The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.,hexose transmembrane transport,biological_process
62676,GO:0008649,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. The methyl group can be transfered to the nucleobase or to the ribose group of the nucleoside.,rRNA methyltransferase activity,molecular_function
62677,GO:0008650,Catalysis of the reaction: a uridine in rRNA + S-adenosyl-L-methionine = a 2'-O-methyluridine in rRNA + S-adenosyl-L-homocysteine + H+.,rRNA (uridine-2'-O-ribose)-methyltransferase activity,molecular_function
62678,GO:0008652,"The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.",amino acid biosynthetic process,biological_process
62679,GO:0008653,"The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.",lipopolysaccharide metabolic process,biological_process
62680,GO:0008654,"The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.",phospholipid biosynthetic process,biological_process
62681,GO:0008655,"Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.",pyrimidine-containing compound salvage,biological_process
62682,GO:0008656,Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.,cysteine-type endopeptidase activator activity involved in apoptotic process,molecular_function
62683,GO:0008657,"Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.","DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity",molecular_function
62684,GO:0008658,"Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.",penicillin binding,molecular_function
62685,GO:0008660,Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanate + NH4.,1-aminocyclopropane-1-carboxylate deaminase activity,molecular_function
62686,GO:0008661,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H+ + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2.,1-deoxy-D-xylulose-5-phosphate synthase activity,molecular_function
62687,GO:0008662,"Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.",1-phosphofructokinase activity,molecular_function
62688,GO:0008663,"Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.","2',3'-cyclic-nucleotide 2'-phosphodiesterase activity",molecular_function
62689,GO:0008664,"Catalysis the reaction: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H+.","RNA 2',3'-cyclic 3'-phosphodiesterase activity",molecular_function
62690,GO:0008666,"Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.","2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity",molecular_function
62691,GO:0008667,"Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ = 2,3-dihydroxybenzoate + H+ + NADH.","2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity",molecular_function
62692,GO:0008668,"Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate.","2,3-dihydroxybenzoate--[aryl-carrier protein] ligase activity",molecular_function
62693,GO:0008670,"Catalysis of the reactions: a 4,5-saturated-(2E)-enoyl-CoA + NADP+ = a (2E,4E)-dienoyl-CoA + H+ + NADPH, and a (2E,4Z)-dienoyl-CoA + H+ + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP+.","2,4-dienoyl-CoA reductase (NADPH) activity",molecular_function
62694,GO:0008671,Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H+.,2-dehydro-3-deoxygalactonokinase activity,molecular_function
62695,GO:0008672,Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.,2-dehydro-3-deoxyglucarate aldolase activity,molecular_function
62696,GO:0008673,Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H+.,2-dehydro-3-deoxygluconokinase activity,molecular_function
62697,GO:0008674,Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate.,2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity,molecular_function
62698,GO:0008675,Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.,2-dehydro-3-deoxy-phosphogluconate aldolase activity,molecular_function
62699,GO:0008676,Catalysis of the reaction: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H+ + phosphate.,3-deoxy-8-phosphooctulonate synthase activity,molecular_function
62700,GO:0008677,Catalysis of the reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + H+ + NADPH.,2-dehydropantoate 2-reductase activity,molecular_function
62701,GO:0008678,Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.,2-deoxy-D-gluconate 3-dehydrogenase activity,molecular_function
62702,GO:0008679,Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.,2-hydroxy-3-oxopropionate reductase activity,molecular_function
62703,GO:0008681,"Catalysis of the reaction: 2-methoxy-6-(all-trans-octaprenyl)phenol + H+ + NADPH + O2 = 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + H2O + NADP+.",2-octaprenyl-6-methoxyphenol hydroxylase activity,molecular_function
62704,GO:0008682,"Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + donor-H2 + O2 = acceptor + a 3-demethylubiquinol + H2O.",3-demethoxyubiquinol 3-hydroxylase activity,molecular_function
62705,GO:0008683,Catalysis of the reaction: 2-oxoglutarate + H+ = CO2 + succinate semialdehyde.,2-oxoglutarate decarboxylase activity,molecular_function
62706,GO:0008684,Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.,2-oxopent-4-enoate hydratase activity,molecular_function
62707,GO:0008685,"Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.","2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity",molecular_function
62708,GO:0008686,Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+.,"3,4-dihydroxy-2-butanone-4-phosphate synthase activity",molecular_function
62709,GO:0008687,"Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O2 = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H+.","3,4-dihydroxyphenylacetate 2,3-dioxygenase activity",molecular_function
62710,GO:0008688,"Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.",3-(3-hydroxyphenyl)propionate hydroxylase activity,molecular_function
62711,GO:0008690,Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.,3-deoxy-manno-octulosonate cytidylyltransferase activity,molecular_function
62712,GO:0008691,Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.,3-hydroxybutyryl-CoA dehydrogenase activity,molecular_function
62713,GO:0008692,Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.,3-hydroxybutyryl-CoA epimerase activity,molecular_function
62714,GO:0008694,Catalysis of the reaction: a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + H+ = a 2-(all-trans-polyprenyl)phenol + CO2.,4-hydroxy-3-polyprenylbenzoate decarboxylase activity,molecular_function
62715,GO:0008695,"Catalysis of the reaction: 3-phenylpropanoate + NADH + O2 + H+ = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+.",3-phenylpropionate dioxygenase activity,molecular_function
62716,GO:0008696,Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H+ + pyruvate.,4-amino-4-deoxychorismate lyase activity,molecular_function
62717,GO:0008697,"Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.",4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity,molecular_function
62718,GO:0008700,Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. Can act on both the (4R) and the (4S) enantiomers of 4-hydroxy-2-oxoglutarate.,"(R,S)-4-hydroxy-2-oxoglutarate aldolase activity",molecular_function
62719,GO:0008701,Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.,4-hydroxy-2-oxovalerate aldolase activity,molecular_function
62720,GO:0008703,Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + H+ + NADPH.,5-amino-6-(5-phosphoribosylamino)uracil reductase activity,molecular_function
62721,GO:0008704,Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.,5-carboxymethyl-2-hydroxymuconate delta-isomerase activity,molecular_function
62722,GO:0008705,"Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.",methionine synthase activity,molecular_function
62723,GO:0008706,"Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.",6-phospho-beta-glucosidase activity,molecular_function
62724,GO:0008707,"Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.",inositol hexakisphosphate 4-phosphatase activity,molecular_function
62725,GO:0008709,"Catalysis of the reaction: cholate + NAD+ = -3alpha,12-alpha-dihydroxy-7-oxo--5beta-cholanate + H+ + NADH.",cholate 7-alpha-dehydrogenase (NAD+) activity,molecular_function
62726,GO:0008710,Catalysis of the reaction: L-alanine + H+ + pimelyl-CoA = 8-amino-7-oxononanoate + CO2 + CoA.,8-amino-7-oxononanoate synthase activity,molecular_function
62727,GO:0008712,Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.,ADP-glyceromanno-heptose 6-epimerase activity,molecular_function
62728,GO:0008713,Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.,ADP-heptose-lipopolysaccharide heptosyltransferase activity,molecular_function
62729,GO:0008714,Catalysis of the reaction: AMP + H2O = D-ribose 5-phosphate + adenine.,AMP nucleosidase activity,molecular_function
62730,GO:0008715,Catalysis of the reaction: CDP-diacylglycerol + H2O = a phosphatidate + CMP + 2 H+.,CDP-diacylglycerol diphosphatase activity,molecular_function
62731,GO:0008716,Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H+ + phosphate.,D-alanine-D-alanine ligase activity,molecular_function
62732,GO:0008718,Catalysis of the reaction: a D-alpha-amino acid + a quinone + H2O = a 2-oxocarboxylate + a quinol + NH4+.,D-amino-acid dehydrogenase activity,molecular_function
62733,GO:0008719,"Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate.",dihydroneopterin triphosphate 2'-epimerase activity,molecular_function
62734,GO:0008720,Catalysis of the reaction: (R)-lactate + NAD+ = H+ + NADH + pyruvate.,D-lactate dehydrogenase (NAD+) activity,molecular_function
62735,GO:0008721,Catalysis of the reaction: D-serine = pyruvate + NH4+.,D-serine ammonia-lyase activity,molecular_function
62736,GO:0008725,"Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.",DNA-3-methyladenine glycosylase activity,molecular_function
62737,GO:0008726,Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.,alkanesulfonate monooxygenase activity,molecular_function
62738,GO:0008727,Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+.,GDP-mannose mannosyl hydrolase activity,molecular_function
62739,GO:0008728,Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.,GTP diphosphokinase activity,molecular_function
62740,GO:0008730,Catalysis of the reaction: L-tartrate = H2O + oxaloacetate.,L(+)-tartrate dehydratase activity,molecular_function
62741,GO:0008732,Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.,L-allo-threonine aldolase activity,molecular_function
62742,GO:0008733,Catalysis of the reaction: L-arabinose = L-ribulose.,L-arabinose isomerase activity,molecular_function
62743,GO:0008734,"Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + H2O2. Can also use fumatate as electron acceptor under anaerobic conditions, yielding succinate.",L-aspartate oxidase activity,molecular_function
62744,GO:0008735,Catalysis of the reactions: (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA and 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.,L-carnitine CoA-transferase activity,molecular_function
62745,GO:0008736,Catalysis of the reaction: L-fucose = L-fuculose.,L-fucose isomerase activity,molecular_function
62746,GO:0008737,Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H+.,L-fuculokinase activity,molecular_function
62747,GO:0008738,Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.,L-fuculose-phosphate aldolase activity,molecular_function
62748,GO:0008740,Catalysis of the reaction: L-rhamnose = L-rhamnulose.,L-rhamnose isomerase activity,molecular_function
62749,GO:0008741,Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.,ribulokinase activity,molecular_function
62750,GO:0008742,Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate.,L-ribulose-phosphate 4-epimerase activity,molecular_function
62751,GO:0008743,Catalysis of the reaction: L-threonine + NAD+ = (2S)-2-amino-3-oxobutanoate + NADH + H+.,L-threonine 3-dehydrogenase activity,molecular_function
62752,GO:0008744,Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.,L-xylulokinase activity,molecular_function
62753,GO:0008745,Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.,N-acetylmuramoyl-L-alanine amidase activity,molecular_function
62754,GO:0008747,Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.,N-acetylneuraminate lyase activity,molecular_function
62755,GO:0008748,Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.,N-ethylmaleimide reductase activity,molecular_function
62756,GO:0008750,Catalysis of the reaction: H+(in) + NAD+ + NADPH = H+(out) + NADH + NADP+.,proton-translocating NAD(P)+ transhydrogenase activity,molecular_function
62757,GO:0008752,Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. This reaction can utilize NADH and NADPH with similar reaction rates.,FMN reductase [NAD(P)H] activity,molecular_function
62758,GO:0008753,Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.,NADPH dehydrogenase (quinone) activity,molecular_function
62759,GO:0008754,Catalysis of the reaction: a lipid-linked O antigen + a lipid A-core oligosaccharide = a lipopolysaccharide + a polyisoprenyl diphosphate.,O-antigen ligase activity,molecular_function
62760,GO:0008755,Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.,O antigen polymerase activity,molecular_function
62761,GO:0008756,Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate.,o-succinylbenzoate-CoA ligase activity,molecular_function
62762,GO:0008757,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.,S-adenosylmethionine-dependent methyltransferase activity,molecular_function
62763,GO:0008758,"Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.","UDP-2,3-diacylglucosamine hydrolase activity",molecular_function
62764,GO:0008760,Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.,UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity,molecular_function
62765,GO:0008761,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.,UDP-N-acetylglucosamine 2-epimerase activity,molecular_function
62766,GO:0008762,Catalysis of the reaction: UDP-N-acetyl-alpha-D-muramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH + H+.,UDP-N-acetylmuramate dehydrogenase activity,molecular_function
62767,GO:0008763,Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanine.,UDP-N-acetylmuramate-L-alanine ligase activity,molecular_function
62768,GO:0008764,Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.,UDP-N-acetylmuramoylalanine-D-glutamate ligase activity,molecular_function
62769,GO:0008765,"Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.","UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity",molecular_function
62770,GO:0008766,"Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.","UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity",molecular_function
62771,GO:0008767,"Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.",UDP-galactopyranose mutase activity,molecular_function
62772,GO:0008768,Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate.,UDP-sugar diphosphatase activity,molecular_function
62773,GO:0008770,Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.,[acyl-carrier-protein] phosphodiesterase activity,molecular_function
62774,GO:0008771,Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form).,[citrate (pro-3S)-lyase] ligase activity,molecular_function
62775,GO:0008772,Catalysis of the reaction: ATP + L-seryl-[isocitrate dehydrogenase] = ADP + H+ + O-phospho-L-seryl-[isocitrate dehydrogenase].,[isocitrate dehydrogenase (NADP+)] kinase activity,molecular_function
62776,GO:0008773,Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).,[protein-PII] uridylyltransferase activity,molecular_function
62777,GO:0008774,Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.,"acetaldehyde dehydrogenase (acetylating, NAD+) activity",molecular_function
62778,GO:0008775,Catalysis of the reaction: an acyl-CoA + acetate = a carboxylate + acetyl-CoA.,acetate CoA-transferase activity,molecular_function
62779,GO:0008776,Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.,acetate kinase activity,molecular_function
62780,GO:0008777,Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.,acetylornithine deacetylase activity,molecular_function
62781,GO:0008779,Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.,acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity,molecular_function
62782,GO:0008780,Catalysis of the reaction: a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP].,acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity,molecular_function
62783,GO:0008781,Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.,N-acylneuraminate cytidylyltransferase activity,molecular_function
62784,GO:0008782,Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.,adenosylhomocysteine nucleosidase activity,molecular_function
62785,GO:0008783,Catalysis of the reaction: agmatine + H2O = putrescine + urea.,agmatinase activity,molecular_function
62786,GO:0008784,Catalysis of the reaction: L-alanine = D-alanine.,alanine racemase activity,molecular_function
62787,GO:0008786,Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.,D-allose 6-phosphate isomerase activity,molecular_function
62788,GO:0008787,Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.,D-allose kinase activity,molecular_function
62789,GO:0008788,"Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.","alpha,alpha-phosphotrehalase activity",molecular_function
62790,GO:0008789,Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O.,altronate dehydratase activity,molecular_function
62791,GO:0008790,Catalysis of the reaction: D-arabinose = D-ribulose.,arabinose isomerase activity,molecular_function
62792,GO:0008791,Catalysis of the reaction: succinyl-CoA + L-arginine = N2-succinyl-L-arginine + CoA + H+.,L-arginine N-succinyltransferase activity,molecular_function
62793,GO:0008792,Catalysis of the reaction: L-arginine + H+ = agmatine + CO2.,arginine decarboxylase activity,molecular_function
62794,GO:0008793,Catalysis of the reaction: an L-alpha aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.,aromatic-amino-acid:2-oxoglutarate transaminase activity,molecular_function
62795,GO:0008794,"Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.",arsenate reductase (glutaredoxin) activity,molecular_function
62796,GO:0008795,Catalysis of the reaction: deamido-NAD+ + NH4+ + ATP = AMP + diphosphate + NAD+ + H+.,NAD+ synthase activity,molecular_function
62797,GO:0008796,"Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.",bis(5'-nucleosyl)-tetraphosphatase activity,molecular_function
62798,GO:0008797,Catalysis of the reaction: L-aspartate = fumarate + NH4+.,aspartate ammonia-lyase activity,molecular_function
62799,GO:0008798,Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.,beta-aspartyl-peptidase activity,molecular_function
62800,GO:0008800,Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.,beta-lactamase activity,molecular_function
62801,GO:0008801,Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.,beta-phosphoglucomutase activity,molecular_function
62802,GO:0008802,Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.,betaine-aldehyde dehydrogenase (NAD+) activity,molecular_function
62803,GO:0008803,"Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H+.",bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity,molecular_function
62804,GO:0008804,Catalysis of the reaction: hydrogencarbonate + NH4+ + ATP = carbamoyl phosphate + ADP + H2O + H+.,carbamate kinase activity,molecular_function
62805,GO:0008805,Catalysis of the reaction: CO + a quinone + H2O = a quinol + CO2.,aerobic carbon monoxide dehydrogenase activity,molecular_function
62806,GO:0008806,Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.,carboxymethylenebutenolidase activity,molecular_function
62807,GO:0008807,Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.,carboxyvinyl-carboxyphosphonate phosphorylmutase activity,molecular_function
62808,GO:0008808,Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.,cardiolipin synthase activity,molecular_function
62809,GO:0008809,Catalysis of the reaction: D-carnitine = L-carnitine.,carnitine racemase activity,molecular_function
62810,GO:0008810,"Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.",cellulase activity,molecular_function
62811,GO:0008811,Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.,chloramphenicol O-acetyltransferase activity,molecular_function
62812,GO:0008812,Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.,choline dehydrogenase activity,molecular_function
62813,GO:0008813,Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate.,chorismate lyase activity,molecular_function
62814,GO:0008814,Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.,citrate CoA-transferase activity,molecular_function
62815,GO:0008815,Catalysis of the reaction: citrate = acetate + oxaloacetate.,citrate (pro-3S)-lyase activity,molecular_function
62816,GO:0008816,Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.,citryl-CoA lyase activity,molecular_function
62817,GO:0008817,"Catalysis of the reaction: 2 ATP + 2 corrinoid + reduced [electron-transfer flavoprotein] = 2 adenosylcorrinoid + 3 H+ + oxidized [electron-transfer flavoprotein] + 2 triphosphate. The corrinoid can be cob(II)yrinate a,c diamide, cob(II)inamide or cob(II)alamin.",corrinoid adenosyltransferase activity,molecular_function
62818,GO:0008818,Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP.,cobalamin 5'-phosphate synthase activity,molecular_function
62819,GO:0008820,Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H+ = adenosylcobinamide-GDP + diphosphate.,cobinamide phosphate guanylyltransferase activity,molecular_function
62820,GO:0008821,Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).,crossover junction DNA endonuclease activity,molecular_function
62821,GO:0008823,Catalysis of the reaction: 2 Cu2+ + NADH = 2 Cu+ + H+ + NAD+.,cupric reductase (NADH) activity,molecular_function
62822,GO:0008824,Catalysis of the reaction: cyanate + hydrogencarbonate + 3 H+ = NH4+ + 2 CO2.,cyanate hydratase activity,molecular_function
62823,GO:0008825,Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.,cyclopropane-fatty-acyl-phospholipid synthase activity,molecular_function
62824,GO:0008826,Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite.,cysteine sulfinate desulfinase activity,molecular_function
62825,GO:0008828,Catalysis of the reaction: dATP + H2O = dAMP + H+ + diphosphate.,dATP diphosphatase activity,molecular_function
62826,GO:0008829,Catalysis of the reaction: dCTP + H2O + H+ = dUTP + NH4+.,dCTP deaminase activity,molecular_function
62827,GO:0008830,Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.,"dTDP-4-dehydrorhamnose 3,5-epimerase activity",molecular_function
62828,GO:0008831,Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + H+ + NADPH.,dTDP-4-dehydrorhamnose reductase activity,molecular_function
62829,GO:0008832,Catalysis of the reaction: dGTP + H2O = 2'-deoxyguanosine + 2 H+ + triphosphate.,dGTPase activity,molecular_function
62830,GO:0008833,Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.,deoxyribonuclease IV (phage-T4-induced) activity,molecular_function
62831,GO:0008834,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate.","ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity",molecular_function
62832,GO:0008835,"Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O + H+ = 5-amino-6-(5-phosphoribosylamino)uracil + NH4.",diaminohydroxyphosphoribosylaminopyrimidine deaminase activity,molecular_function
62833,GO:0008836,"Catalysis of the reaction: meso-2,6-diaminopimelate + H+ = L-lysine + CO2.",diaminopimelate decarboxylase activity,molecular_function
62834,GO:0008837,"Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.",diaminopimelate epimerase activity,molecular_function
62835,GO:0008838,"Catalysis of the reaction: 2,3-diaminopropanoate + H2O + H+ = pyruvate + 2 NH4+.",diaminopropionate ammonia-lyase activity,molecular_function
62836,GO:0008839,"Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.",4-hydroxy-tetrahydrodipicolinate reductase activity,molecular_function
62837,GO:0008840,"Catalysis of the reaction: L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+.",4-hydroxy-tetrahydrodipicolinate synthase activity,molecular_function
62838,GO:0008841,Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate.,dihydrofolate synthase activity,molecular_function
62839,GO:0008843,"Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.",endochitinase activity,molecular_function
62840,GO:0008847,"Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.",Enterobacter ribonuclease activity,molecular_function
62841,GO:0008849,Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.,enterochelin esterase activity,molecular_function
62842,GO:0008851,Catalysis of the reaction: ethanolamine = acetaldehyde + NH4+.,ethanolamine ammonia-lyase activity,molecular_function
62843,GO:0008854,Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.,exodeoxyribonuclease V activity,molecular_function
62844,GO:0008855,Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.,exodeoxyribonuclease VII activity,molecular_function
62845,GO:0008859,Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.,exoribonuclease II activity,molecular_function
62846,GO:0008860,Catalysis of the reaction: 2 reduced [2Fe-2S]-[ferredoxin] + NAD+ + H+ = 2 oxidized [2Fe-2S]-[ferredoxin] + NADH.,ferredoxin-NAD+ reductase activity,molecular_function
62847,GO:0008861,Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.,formate C-acetyltransferase activity,molecular_function
62848,GO:0008863,Catalysis of the reaction: formate + NAD+ = CO2 + NADH.,formate dehydrogenase (NAD+) activity,molecular_function
62849,GO:0008864,"Catalysis of the reaction: 10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H+.",formyltetrahydrofolate deformylase activity,molecular_function
62850,GO:0008865,Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.,fructokinase activity,molecular_function
62851,GO:0008866,Catalysis of the reaction: D-mannonate + NAD+ = D-fructuronate + H+ + NADH.,fructuronate reductase activity,molecular_function
62852,GO:0008867,Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O.,galactarate dehydratase activity,molecular_function
62853,GO:0008868,Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.,galactitol-1-phosphate 5-dehydrogenase activity,molecular_function
62854,GO:0008869,Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O.,galactonate dehydratase activity,molecular_function
62855,GO:0008870,Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.,galactoside O-acetyltransferase activity,molecular_function
62856,GO:0008871,Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.,aminoglycoside 2''-nucleotidyltransferase activity,molecular_function
62857,GO:0008872,Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.,glucarate dehydratase activity,molecular_function
62858,GO:0008873,Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.,gluconate 2-dehydrogenase (NADP+) activity,molecular_function
62859,GO:0008874,Catalysis of the reaction: D-gluconate + NAD(P)+ = 5-dehydro-D-gluconate + NAD(P)H + H+.,gluconate 5-dehydrogenase [NAD(P)+] activity,molecular_function
62860,GO:0008876,"Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.",quinoprotein glucose dehydrogenase activity,molecular_function
62861,GO:0008877,Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.,glucose-1-phosphatase activity,molecular_function
62862,GO:0008878,Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.,glucose-1-phosphate adenylyltransferase activity,molecular_function
62863,GO:0008879,Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose.,glucose-1-phosphate thymidylyltransferase activity,molecular_function
62864,GO:0008880,Catalysis of the reaction: D-glucuronate = D-fructuronate. Also converts D-galacturonate to D-tagaturonate.,glucuronate isomerase activity,molecular_function
62865,GO:0008881,Catalysis of the reaction: L-glutamate = D-glutamate.,glutamate racemase activity,molecular_function
62866,GO:0008882,Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].,[glutamate-ammonia-ligase] adenylyltransferase activity,molecular_function
62867,GO:0008883,Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H+ + NADPH.,glutamyl-tRNA reductase (NADP+) activity,molecular_function
62868,GO:0008884,Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.,glutathionylspermidine amidase activity,molecular_function
62869,GO:0008885,Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.,glutathionylspermidine synthase activity,molecular_function
62870,GO:0008886,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H2O + NADP+ = 3-phospho-D-glycerate + 2 H+ + NADPH.,glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity,molecular_function
62871,GO:0008887,Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H+.,glycerate kinase activity,molecular_function
62872,GO:0008888,Catalysis of the reaction: glycerol + NAD+ = glycerone + H+ + NADH.,glycerol dehydrogenase (NAD+) activity,molecular_function
62873,GO:0008889,Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.,glycerophosphodiester phosphodiesterase activity,molecular_function
62874,GO:0008890,Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA.,glycine C-acetyltransferase activity,molecular_function
62875,GO:0008892,Catalysis of the reaction: guanine + H2O + H+ = xanthine + NH4+.,guanine deaminase activity,molecular_function
62876,GO:0008893,"Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H+.","guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity",molecular_function
62877,GO:0008894,"Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.","guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity",molecular_function
62878,GO:0008897,"Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.",holo-[acyl-carrier-protein] synthase activity,molecular_function
62879,GO:0008898,Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.,S-adenosylmethionine-homocysteine S-methyltransferase activity,molecular_function
62880,GO:0008899,Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA.,homoserine O-succinyltransferase activity,molecular_function
62881,GO:0008900,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).,P-type potassium:proton transporter activity,molecular_function
62882,GO:0008901,Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.,ferredoxin hydrogenase activity,molecular_function
62883,GO:0008902,Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H+.,hydroxymethylpyrimidine kinase activity,molecular_function
62884,GO:0008903,Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate.,hydroxypyruvate isomerase activity,molecular_function
62885,GO:0008904,Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H+.,hygromycin-B 7''-O-phosphotransferase activity,molecular_function
62886,GO:0008906,Catalysis of the reaction: ATP + inosine = ADP + IMP.,inosine kinase activity,molecular_function
62887,GO:0008907,Catalysis of the integration of one DNA segment into another.,integrase activity,molecular_function
62888,GO:0008908,"Catalysis of the reaction: H2O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.",isochorismatase activity,molecular_function
62889,GO:0008909,Catalysis of the reaction: chorismate = isochorismate.,isochorismate synthase activity,molecular_function
62890,GO:0008910,Catalysis of the reaction: ATP + kanamycin = ADP + 2 H+ + kanamycin 3'-phosphate.,kanamycin kinase activity,molecular_function
62891,GO:0008911,Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.,lactaldehyde dehydrogenase (NAD+) activity,molecular_function
62892,GO:0008912,"Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.",lactaldehyde reductase activity,molecular_function
62893,GO:0008913,Catalysis of the reaction: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + holo-[ACP].,Kdo2-lipid IVA acyltransferase activity,molecular_function
62894,GO:0008914,Catalysis of the reaction: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H+ + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu). Can also transfer the leucyl residue on an N-terminal L-lysyl residue.,leucyl-tRNA--protein transferase activity,molecular_function
62895,GO:0008915,"Catalysis of the reaction: a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + UDP + H+.",lipid-A-disaccharide synthase activity,molecular_function
62896,GO:0008917,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.,lipopolysaccharide N-acetylglucosaminyltransferase activity,molecular_function
62897,GO:0008918,"Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.",lipopolysaccharide 3-alpha-galactosyltransferase activity,molecular_function
62898,GO:0008919,Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.,lipopolysaccharide glucosyltransferase I activity,molecular_function
62899,GO:0008920,Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.,lipopolysaccharide heptosyltransferase activity,molecular_function
62900,GO:0008921,"Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.","lipopolysaccharide-1,6-galactosyltransferase activity",molecular_function
62901,GO:0008922,Catalysis of the reaction: a long-chain fatty acid + ATP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid [acyl-carrier-protein] ligase activity,molecular_function
62902,GO:0008923,Catalysis of the reaction: L-lysine + H+ = cadaverine + CO2.,lysine decarboxylase activity,molecular_function
62903,GO:0008924,Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol. Vitamin K (menaquinone) and several other quinones can act as acceptors.,L-malate dehydrogenase (quinone) activity,molecular_function
62904,GO:0008925,Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.,maltose O-acetyltransferase activity,molecular_function
62905,GO:0008926,Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.,mannitol-1-phosphate 5-dehydrogenase activity,molecular_function
62906,GO:0008927,Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.,mannonate dehydratase activity,molecular_function
62907,GO:0008928,Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H+ = GDP-alpha-D-mannose + phosphate.,mannose-1-phosphate guanylyltransferase (GDP) activity,molecular_function
62908,GO:0008929,Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.,methylglyoxal synthase activity,molecular_function
62909,GO:0008930,Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose.,methylthioadenosine nucleosidase activity,molecular_function
62910,GO:0008932,"Catalysis of the endolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.",lytic endotransglycosylase activity,molecular_function
62911,GO:0008933,"Catalysis of the cleavage of a peptidoglycan chain into a peptidoglycan chain with N-acetyl-1,6-anhydromuramyl-[peptide] at the reducing end + a peptidoglycan chain with N-acetylglucosamine at the non-reducing end. Includes endolytic transglycosylase activity that fragments the glycan chain internally and exolytic transgylcosylase activity that cleaves a terminal disaccharide from the end of the glycan strand.",peptidoglycan lytic transglycosylase activity,molecular_function
62912,GO:0008934,Catalysis of the reaction: 1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.,inositol monophosphate 1-phosphatase activity,molecular_function
62913,GO:0008935,"Catalysis of the reaction: 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O.","1,4-dihydroxy-2-naphthoyl-CoA synthase activity",molecular_function
62914,GO:0008936,Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH4+.,nicotinamidase activity,molecular_function
62915,GO:0008937,Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.,ferredoxin-[NAD(P)H] reductase activity,molecular_function
62916,GO:0008938,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine.,nicotinate N-methyltransferase activity,molecular_function
62917,GO:0008939,"Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H+ + nicotinate.",nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity,molecular_function
62918,GO:0008940,Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.,nitrate reductase activity,molecular_function
62919,GO:0008941,Catalysis of the reaction: 2 NO + 2 O2 + NAD(P)H + H+ = 2 nitrate + NAD(P)+.,nitric oxide dioxygenase [NAD(P)H] activity,molecular_function
62920,GO:0008942,Catalysis of the reaction: NH4+ + 3 NAD(P)+ + 2 H2O = nitrite + 3 NAD(P)H + 5 H+.,nitrite reductase [NAD(P)H] activity,molecular_function
62921,GO:0008948,Catalysis of the reaction: H+ + oxaloacetate = CO2 + pyruvate.,oxaloacetate decarboxylase activity,molecular_function
62922,GO:0008949,Catalysis of the reaction: H+ + oxalyl-CoA = CO2 + formyl-CoA.,oxalyl-CoA decarboxylase activity,molecular_function
62923,GO:0008951,Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].,palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity,molecular_function
62924,GO:0008953,Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.,penicillin amidase activity,molecular_function
62925,GO:0008955,"Catalysis of the reaction: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H+.",peptidoglycan glycosyltransferase activity,molecular_function
62926,GO:0008957,Catalysis of the reaction: 2-phenylacetaldehyde + H2O + NAD+ = 2-phenylacetate + 2 H+ + NADH.,phenylacetaldehyde dehydrogenase (NAD+) activity,molecular_function
62927,GO:0008959,Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.,phosphate acetyltransferase activity,molecular_function
62928,GO:0008960,"Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.",phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity,molecular_function
62929,GO:0008961,Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.,phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity,molecular_function
62930,GO:0008962,Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.,phosphatidylglycerophosphatase activity,molecular_function
62931,GO:0008963,"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine = Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP.",phospho-N-acetylmuramoyl-pentapeptide-transferase activity,molecular_function
62932,GO:0008964,Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.,phosphoenolpyruvate carboxylase activity,molecular_function
62933,GO:0008965,Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.,phosphoenolpyruvate-protein phosphotransferase activity,molecular_function
62934,GO:0008966,Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.,phosphoglucosamine mutase activity,molecular_function
62935,GO:0008967,Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate.,phosphoglycolate phosphatase activity,molecular_function
62936,GO:0008968,"Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate.",D-sedoheptulose 7-phosphate isomerase activity,molecular_function
62937,GO:0008970,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H+. Note that the substrate has a diacyl group attached to the glycerol group.",glycerophospholipid phospholipase A1 activity,molecular_function
62938,GO:0008972,Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.,phosphomethylpyrimidine kinase activity,molecular_function
62939,GO:0008973,Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate. Also converts 2-deoxy-alpha-D-ribose 1-phosphate into 2-deoxy-D-ribose 5-phosphate.,phosphopentomutase activity,molecular_function
62940,GO:0008974,"Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H+.",phosphoribulokinase activity,molecular_function
62941,GO:0008976,Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).,polyphosphate kinase activity,molecular_function
62942,GO:0008977,Catalysis of the reaction: NAD+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADH.,prephenate dehydrogenase (NAD+) activity,molecular_function
62943,GO:0008979,"Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA.",prophage integrase activity,molecular_function
62944,GO:0008980,Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.,propionate kinase activity,molecular_function
62945,GO:0008982,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity,molecular_function
62946,GO:0008983,Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.,protein-glutamate O-methyltransferase activity,molecular_function
62947,GO:0008984,Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.,protein-glutamate methylesterase activity,molecular_function
62948,GO:0008986,Catalysis of the reaction: ATP + H2O + pyruvate = AMP + 2 H+ + phosphate + phosphoenolpyruvate.,"pyruvate, water dikinase activity",molecular_function
62949,GO:0008987,Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.,quinolinate synthetase A activity,molecular_function
62950,GO:0008988,Catalysis of the reaction: adenosine in rRNA + S-adenosyl-L-methionine = H+ + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine.,rRNA (adenine-N6-)-methyltransferase activity,molecular_function
62951,GO:0008989,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.,rRNA (guanine-N1-)-methyltransferase activity,molecular_function
62952,GO:0008990,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.,rRNA (guanine-N2-)-methyltransferase activity,molecular_function
62953,GO:0008993,Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.,rhamnulokinase activity,molecular_function
62954,GO:0008994,Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.,rhamnulose-1-phosphate aldolase activity,molecular_function
62955,GO:0008995,"Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.",ribonuclease E activity,molecular_function
62956,GO:0008998,Catalysis of the reaction: [thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-triphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-triphosphate.,ribonucleoside-triphosphate reductase (thioredoxin) activity,molecular_function
62957,GO:0008999,Catalysis of the reaction: acetyl-CoA + N-terminal L-alanyl-[protein] = CoA + H+ + N-terminal N(alpha)-acetyl-L-alanyl-[protein].,protein-N-terminal-alanine acetyltransferase activity,molecular_function
62958,GO:0009000,Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.,selenocysteine lyase activity,molecular_function
62959,GO:0009001,Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.,L-serine O-acetyltransferase activity,molecular_function
62960,GO:0009002,Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.,serine-type D-Ala-D-Ala carboxypeptidase activity,molecular_function
62961,GO:0009003,"An endopeptidase that cleaves a hydrophobic, N-terminal signal or leader sequences from mitochondrial, secreted and periplasmic proteins.",signal peptidase activity,molecular_function
62962,GO:0009007,Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.,site-specific DNA-methyltransferase (adenine-specific) activity,molecular_function
62963,GO:0009008,Catalysis of the transfer of a methyl group to a DNA molecule.,DNA-methyltransferase activity,molecular_function
62964,GO:0009009,"Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences.",site-specific recombinase activity,molecular_function
62965,GO:0009010,Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.,sorbitol-6-phosphate 2-dehydrogenase activity,molecular_function
62966,GO:0009011,Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + ADP + H+.,"alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity",molecular_function
62967,GO:0009012,Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H+.,aminoglycoside 3''-adenylyltransferase activity,molecular_function
62968,GO:0009013,Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.,succinate-semialdehyde dehydrogenase [NAD(P)+] activity,molecular_function
62969,GO:0009014,"Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + succinate.",succinyl-diaminopimelate desuccinylase activity,molecular_function
62970,GO:0009015,Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H2O + 2 H+ = N(2)-succinyl-L-ornithine + CO2 + 2 NH4.,N-succinylarginine dihydrolase activity,molecular_function
62971,GO:0009016,"Catalysis of the reaction: N-succinyl-(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate.",succinyldiaminopimelate:2-oxoglutarate transaminase activity,molecular_function
62972,GO:0009017,Catalysis of the reaction: N-succinyl-L-glutamate + H2O = L-glutamate + succinate.,succinylglutamate desuccinylase activity,molecular_function
62973,GO:0009018,Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.,sucrose phosphorylase activity,molecular_function
62974,GO:0009022,Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.,tRNA nucleotidyltransferase activity,molecular_function
62975,GO:0009024,"Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.",tagatose-6-phosphate kinase activity,molecular_function
62976,GO:0009025,"Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate.",tagatose-bisphosphate aldolase activity,molecular_function
62977,GO:0009026,Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.,tagaturonate reductase activity,molecular_function
62978,GO:0009027,Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.,tartrate dehydrogenase activity,molecular_function
62979,GO:0009028,Catalysis of the reaction: 2 glyoxylate + H+ = 2-hydroxy-3-oxopropanoate + CO2.,tartronate-semialdehyde synthase activity,molecular_function
62980,GO:0009029,Catalysis of the reaction: a lipid A disaccharide + ATP = a lipid IVA + ADP + H+.,lipid-A 4'-kinase activity,molecular_function
62981,GO:0009030,Catalysis of the reaction: ATP + thiamine phosphate = ADP + H+ + thiamine diphosphate.,thiamine-phosphate kinase activity,molecular_function
62982,GO:0009032,Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.,thymidine phosphorylase activity,molecular_function
62983,GO:0009034,Catalysis of the reaction: L-tryptophan + H2O = indole + NH4 + pyruvate.,tryptophanase activity,molecular_function
62984,GO:0009035,"Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.",type I site-specific deoxyribonuclease activity,molecular_function
62985,GO:0009036,Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.,type II site-specific deoxyribonuclease activity,molecular_function
62986,GO:0009037,"Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.",tyrosine-based site-specific recombinase activity,molecular_function
62987,GO:0009038,Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.,undecaprenol kinase activity,molecular_function
62988,GO:0009039,Catalysis of the reaction: urea + 2 H2O + H+ = hydrogencarbonate + 2 NH4+.,urease activity,molecular_function
62989,GO:0009040,Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.,ureidoglycolate dehydrogenase activity,molecular_function
62990,GO:0009042,Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.,L-valine:pyruvate transaminase activity,molecular_function
62991,GO:0009044,Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.,"xylan 1,4-beta-xylosidase activity",molecular_function
62992,GO:0009045,Catalysis of the reaction: alpha-D-xylose = alpha-D-xylulofuranose.,xylose isomerase activity,molecular_function
62993,GO:0009046,Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.,zinc D-Ala-D-Ala carboxypeptidase activity,molecular_function
62994,GO:0009047,"Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.",dosage compensation by hyperactivation of X chromosome,biological_process
62995,GO:0009048,"Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by heterochromatin formation leading to a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.",dosage compensation by inactivation of X chromosome,biological_process
62996,GO:0009050,"The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.",glycopeptide catabolic process,biological_process
62997,GO:0009051,"The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).","pentose-phosphate shunt, oxidative branch",biological_process
62998,GO:0009052,"The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.","pentose-phosphate shunt, non-oxidative branch",biological_process
62999,GO:0009055,"A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways.",electron transfer activity,molecular_function
63000,GO:0009056,A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.,catabolic process,biological_process
63001,GO:0009057,"The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",macromolecule catabolic process,biological_process
63002,GO:0009058,A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.,biosynthetic process,biological_process
63003,GO:0009059,"The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",macromolecule biosynthetic process,biological_process
63004,GO:0009060,The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.,aerobic respiration,biological_process
63005,GO:0009061,"The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.",anaerobic respiration,biological_process
63006,GO:0009062,"The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.",fatty acid catabolic process,biological_process
63007,GO:0009063,"The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.",amino acid catabolic process,biological_process
63008,GO:0009067,"The chemical reactions and pathways resulting in the formation of L-aspartate or any of the amino acids synthesised from it (L-asparagine, L-lysine, L-methionine, L-threonine and L-isoleucine).",aspartate family amino acid biosynthetic process,biological_process
63009,GO:0009070,"The chemical reactions and pathways resulting in the formation of an amino acid derived from 3-phosphoglycerate (L-serine, glycine, L-cysteine and L-homocysteine).",serine family amino acid biosynthetic process,biological_process
63010,GO:0009072,"The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).",aromatic amino acid metabolic process,biological_process
63011,GO:0009073,The chemical reactions and pathways resulting in the formation of an amino acid whose structure includes an aromatic ring.,aromatic amino acid biosynthetic process,biological_process
63012,GO:0009074,The chemical reactions and pathways resulting in the breakdown of an amino acid whose structure includes an aromatic ring.,aromatic amino acid catabolic process,biological_process
63013,GO:0009079,"The chemical reactions and pathways resulting in the formation of an L-amino acid derived from pyruvate (L-alanine, L-valine, and L-leucine).",pyruvate family amino acid biosynthetic process,biological_process
63014,GO:0009081,"The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.",branched-chain amino acid metabolic process,biological_process
63015,GO:0009082,"The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.",branched-chain amino acid biosynthetic process,biological_process
63016,GO:0009083,"The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.",branched-chain amino acid catabolic process,biological_process
63017,GO:0009084,"The chemical reactions and pathways resulting in the formation of L-glutamate or any of the amino acids synthesised from it (L-glutamine, L-proline and L-arginine).",glutamate family amino acid biosynthetic process,biological_process
63018,GO:0009085,"The chemical reactions and pathways resulting in the formation of L-lysine, 2,6-diaminohexanoic acid.",L-lysine biosynthetic process,biological_process
63019,GO:0009087,The chemical reactions and pathways resulting in the breakdown of L-methionine.,L-methionine catabolic process,biological_process
63020,GO:0009088,"The chemical reactions and pathways resulting in the formation of L-threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.",L-threonine biosynthetic process,biological_process
63021,GO:0009090,"The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.",L-homoserine biosynthetic process,biological_process
63022,GO:0009092,"The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.",L-homoserine metabolic process,biological_process
63023,GO:0009094,"The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.",L-phenylalanine biosynthetic process,biological_process
63024,GO:0009098,"The chemical reactions and pathways resulting in the formation of L-leucine, 2-amino-4-methylpentanoic acid.",L-leucine biosynthetic process,biological_process
63025,GO:0009099,"The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.",L-valine biosynthetic process,biological_process
63026,GO:0009100,"The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",glycoprotein metabolic process,biological_process
63027,GO:0009101,"The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",glycoprotein biosynthetic process,biological_process
63028,GO:0009102,"The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.",biotin biosynthetic process,biological_process
63029,GO:0009103,"The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.",lipopolysaccharide biosynthetic process,biological_process
63030,GO:0009104,"The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.",lipopolysaccharide catabolic process,biological_process
63031,GO:0009106,"The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.",lipoate metabolic process,biological_process
63032,GO:0009107,"The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.",lipoate biosynthetic process,biological_process
63033,GO:0009110,"The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",vitamin biosynthetic process,biological_process
63034,GO:0009111,"The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body, carried out by individual cells.",vitamin catabolic process,biological_process
63035,GO:0009112,"The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.",nucleobase metabolic process,biological_process
63036,GO:0009113,"The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.",purine nucleobase biosynthetic process,biological_process
63037,GO:0009114,"The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.",hypoxanthine catabolic process,biological_process
63038,GO:0009115,"The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.",xanthine catabolic process,biological_process
63039,GO:0009116,"The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).",nucleoside metabolic process,biological_process
63040,GO:0009117,"The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).",nucleotide metabolic process,biological_process
63041,GO:0009118,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.",regulation of nucleoside metabolic process,biological_process
63042,GO:0009119,"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",ribonucleoside metabolic process,biological_process
63043,GO:0009120,The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,2'-deoxyribonucleoside metabolic process,biological_process
63044,GO:0009123,"The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.",nucleoside monophosphate metabolic process,biological_process
63045,GO:0009124,"The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.",nucleoside monophosphate biosynthetic process,biological_process
63046,GO:0009125,"The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.",nucleoside monophosphate catabolic process,biological_process
63047,GO:0009126,"The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",purine nucleoside monophosphate metabolic process,biological_process
63048,GO:0009127,"The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",purine nucleoside monophosphate biosynthetic process,biological_process
63049,GO:0009128,"The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",purine nucleoside monophosphate catabolic process,biological_process
63050,GO:0009129,"The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine nucleoside monophosphate metabolic process,biological_process
63051,GO:0009130,"The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine nucleoside monophosphate biosynthetic process,biological_process
63052,GO:0009131,"The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine nucleoside monophosphate catabolic process,biological_process
63053,GO:0009132,"The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.",nucleoside diphosphate metabolic process,biological_process
63054,GO:0009133,"The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.",nucleoside diphosphate biosynthetic process,biological_process
63055,GO:0009134,"The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.",nucleoside diphosphate catabolic process,biological_process
63056,GO:0009135,"The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",purine nucleoside diphosphate metabolic process,biological_process
63057,GO:0009136,"The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",purine nucleoside diphosphate biosynthetic process,biological_process
63058,GO:0009137,"The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",purine nucleoside diphosphate catabolic process,biological_process
63059,GO:0009138,"The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine nucleoside diphosphate metabolic process,biological_process
63060,GO:0009139,"The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine nucleoside diphosphate biosynthetic process,biological_process
63061,GO:0009140,"The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine nucleoside diphosphate catabolic process,biological_process
63062,GO:0009141,"The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.",nucleoside triphosphate metabolic process,biological_process
63063,GO:0009142,"The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.",nucleoside triphosphate biosynthetic process,biological_process
63064,GO:0009143,"The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.",nucleoside triphosphate catabolic process,biological_process
63065,GO:0009144,"The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",purine nucleoside triphosphate metabolic process,biological_process
63066,GO:0009145,"The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",purine nucleoside triphosphate biosynthetic process,biological_process
63067,GO:0009146,"The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",purine nucleoside triphosphate catabolic process,biological_process
63068,GO:0009147,"The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine nucleoside triphosphate metabolic process,biological_process
63069,GO:0009148,"The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine nucleoside triphosphate biosynthetic process,biological_process
63070,GO:0009149,"The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine nucleoside triphosphate catabolic process,biological_process
63071,GO:0009150,"The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine ribonucleotide metabolic process,biological_process
63072,GO:0009151,"The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine deoxyribonucleotide metabolic process,biological_process
63073,GO:0009152,"The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine ribonucleotide biosynthetic process,biological_process
63074,GO:0009153,"The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine deoxyribonucleotide biosynthetic process,biological_process
63075,GO:0009154,"The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine ribonucleotide catabolic process,biological_process
63076,GO:0009155,"The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",purine deoxyribonucleotide catabolic process,biological_process
63077,GO:0009156,"The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.",ribonucleoside monophosphate biosynthetic process,biological_process
63078,GO:0009157,"The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.",deoxyribonucleoside monophosphate biosynthetic process,biological_process
63079,GO:0009158,"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.",ribonucleoside monophosphate catabolic process,biological_process
63080,GO:0009159,"The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.",deoxyribonucleoside monophosphate catabolic process,biological_process
63081,GO:0009163,The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).,nucleoside biosynthetic process,biological_process
63082,GO:0009164,The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).,nucleoside catabolic process,biological_process
63083,GO:0009165,"The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).",nucleotide biosynthetic process,biological_process
63084,GO:0009166,"The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).",nucleotide catabolic process,biological_process
63085,GO:0009167,"The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.",purine ribonucleoside monophosphate metabolic process,biological_process
63086,GO:0009168,"The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.",purine ribonucleoside monophosphate biosynthetic process,biological_process
63087,GO:0009169,"The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.",purine ribonucleoside monophosphate catabolic process,biological_process
63088,GO:0009170,"The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",purine deoxyribonucleoside monophosphate metabolic process,biological_process
63089,GO:0009171,"The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",purine deoxyribonucleoside monophosphate biosynthetic process,biological_process
63090,GO:0009172,"The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",purine deoxyribonucleoside monophosphate catabolic process,biological_process
63091,GO:0009173,"The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.",pyrimidine ribonucleoside monophosphate metabolic process,biological_process
63092,GO:0009174,"The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.",pyrimidine ribonucleoside monophosphate biosynthetic process,biological_process
63093,GO:0009175,"The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.",pyrimidine ribonucleoside monophosphate catabolic process,biological_process
63094,GO:0009176,"The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine deoxyribonucleoside monophosphate metabolic process,biological_process
63095,GO:0009177,"The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine deoxyribonucleoside monophosphate biosynthetic process,biological_process
63096,GO:0009178,"The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.",pyrimidine deoxyribonucleoside monophosphate catabolic process,biological_process
63097,GO:0009179,"The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.",purine ribonucleoside diphosphate metabolic process,biological_process
63098,GO:0009180,"The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.",purine ribonucleoside diphosphate biosynthetic process,biological_process
63099,GO:0009181,"The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.",purine ribonucleoside diphosphate catabolic process,biological_process
63100,GO:0009182,"The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",purine deoxyribonucleoside diphosphate metabolic process,biological_process
63101,GO:0009183,"The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",purine deoxyribonucleoside diphosphate biosynthetic process,biological_process
63102,GO:0009184,"The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",purine deoxyribonucleoside diphosphate catabolic process,biological_process
63103,GO:0009185,"The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.",ribonucleoside diphosphate metabolic process,biological_process
63104,GO:0009187,"The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.",cyclic nucleotide metabolic process,biological_process
63105,GO:0009188,"The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.",ribonucleoside diphosphate biosynthetic process,biological_process
63106,GO:0009189,"The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.",deoxyribonucleoside diphosphate biosynthetic process,biological_process
63107,GO:0009190,"The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.",cyclic nucleotide biosynthetic process,biological_process
63108,GO:0009191,"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.",ribonucleoside diphosphate catabolic process,biological_process
63109,GO:0009192,"The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.",deoxyribonucleoside diphosphate catabolic process,biological_process
63110,GO:0009193,"The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.",pyrimidine ribonucleoside diphosphate metabolic process,biological_process
63111,GO:0009194,"The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.",pyrimidine ribonucleoside diphosphate biosynthetic process,biological_process
63112,GO:0009195,"The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.",pyrimidine ribonucleoside diphosphate catabolic process,biological_process
63113,GO:0009196,"The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine deoxyribonucleoside diphosphate metabolic process,biological_process
63114,GO:0009197,"The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine deoxyribonucleoside diphosphate biosynthetic process,biological_process
63115,GO:0009198,"The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.",pyrimidine deoxyribonucleoside diphosphate catabolic process,biological_process
63116,GO:0009200,"The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.",deoxyribonucleoside triphosphate metabolic process,biological_process
63117,GO:0009201,"The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.",ribonucleoside triphosphate biosynthetic process,biological_process
63118,GO:0009202,"The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.",deoxyribonucleoside triphosphate biosynthetic process,biological_process
63119,GO:0009203,"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.",ribonucleoside triphosphate catabolic process,biological_process
63120,GO:0009204,"The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.",deoxyribonucleoside triphosphate catabolic process,biological_process
63121,GO:0009205,"The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.",purine ribonucleoside triphosphate metabolic process,biological_process
63122,GO:0009206,"The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.",purine ribonucleoside triphosphate biosynthetic process,biological_process
63123,GO:0009207,"The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.",purine ribonucleoside triphosphate catabolic process,biological_process
63124,GO:0009208,"The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.",pyrimidine ribonucleoside triphosphate metabolic process,biological_process
63125,GO:0009209,"The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.",pyrimidine ribonucleoside triphosphate biosynthetic process,biological_process
63126,GO:0009210,"The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.",pyrimidine ribonucleoside triphosphate catabolic process,biological_process
63127,GO:0009211,"The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine deoxyribonucleoside triphosphate metabolic process,biological_process
63128,GO:0009212,"The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine deoxyribonucleoside triphosphate biosynthetic process,biological_process
63129,GO:0009213,"The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",pyrimidine deoxyribonucleoside triphosphate catabolic process,biological_process
63130,GO:0009214,"The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.",cyclic nucleotide catabolic process,biological_process
63131,GO:0009215,"The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",purine deoxyribonucleoside triphosphate metabolic process,biological_process
63132,GO:0009216,"The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",purine deoxyribonucleoside triphosphate biosynthetic process,biological_process
63133,GO:0009217,"The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.",purine deoxyribonucleoside triphosphate catabolic process,biological_process
63134,GO:0009218,"The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine ribonucleotide metabolic process,biological_process
63135,GO:0009219,"The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine deoxyribonucleotide metabolic process,biological_process
63136,GO:0009220,"The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine ribonucleotide biosynthetic process,biological_process
63137,GO:0009221,"The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine deoxyribonucleotide biosynthetic process,biological_process
63138,GO:0009222,"The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine ribonucleotide catabolic process,biological_process
63139,GO:0009223,"The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",pyrimidine deoxyribonucleotide catabolic process,biological_process
63140,GO:0009224,"The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.",CMP biosynthetic process,biological_process
63141,GO:0009225,"The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.",nucleotide-sugar metabolic process,biological_process
63142,GO:0009226,"The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.",nucleotide-sugar biosynthetic process,biological_process
63143,GO:0009228,"The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine biosynthetic process,biological_process
63144,GO:0009229,"The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.",thiamine diphosphate biosynthetic process,biological_process
63145,GO:0009230,"The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine catabolic process,biological_process
63146,GO:0009231,"The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).",riboflavin biosynthetic process,biological_process
63147,GO:0009232,"The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).",riboflavin catabolic process,biological_process
63148,GO:0009233,"The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.",menaquinone metabolic process,biological_process
63149,GO:0009234,"The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.",menaquinone biosynthetic process,biological_process
63150,GO:0009235,"The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.",cobalamin metabolic process,biological_process
63151,GO:0009236,"The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.",cobalamin biosynthetic process,biological_process
63152,GO:0009237,"The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.",siderophore metabolic process,biological_process
63153,GO:0009239,"The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.",enterobactin biosynthetic process,biological_process
63154,GO:0009240,"The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.",isopentenyl diphosphate biosynthetic process,biological_process
63155,GO:0009242,"The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.",colanic acid biosynthetic process,biological_process
63156,GO:0009243,"The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.",O antigen biosynthetic process,biological_process
63157,GO:0009244,"The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.",lipopolysaccharide core region biosynthetic process,biological_process
63158,GO:0009245,"The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.",lipid A biosynthetic process,biological_process
63159,GO:0009246,"The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.",enterobacterial common antigen biosynthetic process,biological_process
63160,GO:0009247,"The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).",glycolipid biosynthetic process,biological_process
63161,GO:0009248,"The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.",K antigen biosynthetic process,biological_process
63162,GO:0009249,The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.,protein lipoylation,biological_process
63163,GO:0009250,"The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.",glucan biosynthetic process,biological_process
63164,GO:0009251,"The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.",glucan catabolic process,biological_process
63165,GO:0009252,"The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides.",peptidoglycan biosynthetic process,biological_process
63166,GO:0009253,"The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides.",peptidoglycan catabolic process,biological_process
63167,GO:0009254,"The continual breakdown and regeneration of peptidoglycan required to maintain the bacterial cell wall. Peptidoglycans consist of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides.",peptidoglycan turnover,biological_process
63168,GO:0009256,"The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.",10-formyltetrahydrofolate metabolic process,biological_process
63169,GO:0009257,"The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.",10-formyltetrahydrofolate biosynthetic process,biological_process
63170,GO:0009258,"The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.",10-formyltetrahydrofolate catabolic process,biological_process
63171,GO:0009259,"The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",ribonucleotide metabolic process,biological_process
63172,GO:0009260,"The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",ribonucleotide biosynthetic process,biological_process
63173,GO:0009261,"The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",ribonucleotide catabolic process,biological_process
63174,GO:0009262,"The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",deoxyribonucleotide metabolic process,biological_process
63175,GO:0009263,"The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",deoxyribonucleotide biosynthetic process,biological_process
63176,GO:0009264,"The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",deoxyribonucleotide catabolic process,biological_process
63177,GO:0009265,"The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",2'-deoxyribonucleotide biosynthetic process,biological_process
63178,GO:0009266,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.",response to temperature stimulus,biological_process
63179,GO:0009267,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.",cellular response to starvation,biological_process
63180,GO:0009268,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.",response to pH,biological_process
63181,GO:0009269,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.",response to desiccation,biological_process
63182,GO:0009270,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.",response to humidity,biological_process
63183,GO:0009271,"A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.",phage shock,biological_process
63184,GO:0009272,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.",fungal-type cell wall biogenesis,biological_process
63185,GO:0009273,The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli.,peptidoglycan-based cell wall biogenesis,biological_process
63186,GO:0009274,"A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.",peptidoglycan-based cell wall,cellular_component
63187,GO:0009275,"A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria.",Gram-positive-bacterium-type cell wall,cellular_component
63188,GO:0009276,The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain.,Gram-negative-bacterium-type cell wall,cellular_component
63189,GO:0009277,"A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not c...",fungal-type cell wall,cellular_component
63190,GO:0009279,A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.,cell outer membrane,cellular_component
63191,GO:0009288,A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.,bacterial-type flagellum,cellular_component
63192,GO:0009289,A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.,pilus,cellular_component
63193,GO:0009290,"The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.",DNA import into cell involved in transformation,biological_process
63194,GO:0009291,The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells. Some or all of the chromosome(s) of the donor cell is transferred into the recipient cell.,unidirectional conjugation,biological_process
63195,GO:0009292,"The introduction of genetic information into a cell to create a genetically different individual, without production of new individuals.",horizontal gene transfer,biological_process
63196,GO:0009293,A type of horizontal gene transfer in which genetic material is introduced into a cell mediated by a virus.,transduction,biological_process
63197,GO:0009294,The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.,DNA-mediated transformation,biological_process
63198,GO:0009295,"The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.",nucleoid,cellular_component
63199,GO:0009297,"The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles.",pilus assembly,biological_process
63200,GO:0009298,"The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.",GDP-mannose biosynthetic process,biological_process
63201,GO:0009299,The cellular synthesis of messenger RNA (mRNA) from a DNA template.,mRNA transcription,biological_process
63202,GO:0009300,"The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.",antisense RNA transcription,biological_process
63203,GO:0009301,The synthesis of small nuclear RNA (snRNA) from a DNA template.,snRNA transcription,biological_process
63204,GO:0009302,The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template.,sno(s)RNA transcription,biological_process
63205,GO:0009303,"The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.",rRNA transcription,biological_process
63206,GO:0009304,The synthesis of transfer RNA (tRNA) from a DNA template.,tRNA transcription,biological_process
63207,GO:0009306,The controlled release of proteins from a cell.,protein secretion,biological_process
63208,GO:0009307,"A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.",DNA restriction-modification system,biological_process
63209,GO:0009308,"The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.",amine metabolic process,biological_process
63210,GO:0009309,"The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.",amine biosynthetic process,biological_process
63211,GO:0009310,"The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.",amine catabolic process,biological_process
63212,GO:0009311,"The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.",oligosaccharide metabolic process,biological_process
63213,GO:0009312,"The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.",oligosaccharide biosynthetic process,biological_process
63214,GO:0009313,"The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.",oligosaccharide catabolic process,biological_process
63215,GO:0009314,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.",response to radiation,biological_process
63216,GO:0009316,"A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.",3-isopropylmalate dehydratase complex,cellular_component
63217,GO:0009317,"A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.",acetyl-CoA carboxylase complex,cellular_component
63218,GO:0009318,An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.,exodeoxyribonuclease VII complex,cellular_component
63219,GO:0009319,A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups.,cytochrome o ubiquinol oxidase complex,cellular_component
63220,GO:0009320,A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity.,phosphoribosylaminoimidazole carboxylase complex,cellular_component
63221,GO:0009321,"An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.",alkyl hydroperoxide reductase complex,cellular_component
63222,GO:0009324,A protein complex that possesses D-amino-acid dehydrogenase activity.,D-amino-acid dehydrogenase complex,cellular_component
63223,GO:0009325,An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.,nitrate reductase complex,cellular_component
63224,GO:0009326,An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).,formate dehydrogenase complex,cellular_component
63225,GO:0009328,"An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).",phenylalanine-tRNA ligase complex,cellular_component
63226,GO:0009329,A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA.,acetate CoA-transferase complex,cellular_component
63227,GO:0009330,"Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity.","DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex",cellular_component
63228,GO:0009331,"An enzyme complex that catalyzes the oxidation of sn-glycerol 3-phosphate to dihydroxyacetone phosphate, with concurrent reduction of flavin adenine dinucleotide (FAD) to FADH2. In E. coli, the complex is either a GlpA-GlpB-GlpC heterotrimer that functions in anaerobic conditions, or a GlpD homodimer that functions in aerobic conditions.",glycerol-3-phosphate dehydrogenase (FAD) complex,cellular_component
63229,GO:0009332,An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu).,glutamate-tRNA ligase complex,cellular_component
63230,GO:0009333,"Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.",cysteine synthase complex,cellular_component
63231,GO:0009334,"Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).",3-phenylpropionate dioxygenase complex,cellular_component
63232,GO:0009336,An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.,sulfate adenylyltransferase complex (ATP),cellular_component
63233,GO:0009337,"A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.",sulfite reductase complex (NADPH),cellular_component
63234,GO:0009338,An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.,exodeoxyribonuclease V complex,cellular_component
63235,GO:0009339,An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and H2O2. The enzyme is a flavoprotein (FMN).,glycolate oxidase complex,cellular_component
63236,GO:0009340,"A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA.",DNA topoisomerase IV complex,cellular_component
63237,GO:0009341,"A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.",beta-galactosidase complex,cellular_component
63238,GO:0009342,A complex that possesses glutamate synthase (NADPH) activity.,glutamate synthase complex (NADPH),cellular_component
63239,GO:0009344,Complex that possesses nitrite reductase [NAD(P)H] activity.,nitrite reductase complex [NAD(P)H],cellular_component
63240,GO:0009345,"A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly).",glycine-tRNA ligase complex,cellular_component
63241,GO:0009346,"Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. This enzyme has only been found in bacteria.",ATP-independent citrate lyase complex,cellular_component
63242,GO:0009347,"A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.",aspartate carbamoyltransferase complex,cellular_component
63243,GO:0009349,An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.,riboflavin synthase complex,cellular_component
63244,GO:0009350,An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.,ethanolamine ammonia-lyase complex,cellular_component
63245,GO:0009355,"A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.",DNA polymerase V complex,cellular_component
63246,GO:0009356,A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity.,aminodeoxychorismate synthase complex,cellular_component
63247,GO:0009357,An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system.,protein-N(PI)-phosphohistidine-sugar phosphotransferase complex,cellular_component
63248,GO:0009358,A protein complex that possesses polyphosphate kinase activity.,polyphosphate kinase complex,cellular_component
63249,GO:0009359,"A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.",type II site-specific deoxyribonuclease complex,cellular_component
63250,GO:0009360,"The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivit...",DNA polymerase III complex,cellular_component
63251,GO:0009361,"A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP.",succinate-CoA ligase complex (ADP-forming),cellular_component
63252,GO:0009365,A complex that possesses protein histidine kinase activity.,protein histidine kinase complex,cellular_component
63253,GO:0009366,"A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway.",enterobactin synthetase complex,cellular_component
63254,GO:0009368,"A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.",endopeptidase Clp complex,cellular_component
63255,GO:0009372,"The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.",quorum sensing,biological_process
63256,GO:0009374,"Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.",biotin binding,molecular_function
63257,GO:0009375,"An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.",ferredoxin hydrogenase complex,cellular_component
63258,GO:0009376,"A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.",HslUV protease complex,cellular_component
63259,GO:0009378,"Unwinding a DNA helix of DNA containing four-way junctions, including Holliday junctions, driven by ATP hydrolysis.",four-way junction helicase activity,molecular_function
63260,GO:0009379,"A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.",Holliday junction helicase complex,cellular_component
63261,GO:0009380,"Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to...",excinuclease repair complex,cellular_component
63262,GO:0009381,Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind.,excinuclease ABC activity,molecular_function
63263,GO:0009382,Complex that possesses imidazoleglycerol-phosphate synthase activity.,imidazoleglycerol-phosphate synthase complex,cellular_component
63264,GO:0009383,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.,rRNA (cytosine-C5-)-methyltransferase activity,molecular_function
63265,GO:0009384,Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.,N-acylmannosamine kinase activity,molecular_function
63266,GO:0009386,"Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The...",translational attenuation,biological_process
63267,GO:0009389,Catalysis of the reaction: dimethyl sulfide + a menaquinone + H2O = dimethyl sulfoxide + a menaquinol.,dimethyl sulfoxide reductase activity,molecular_function
63268,GO:0009390,An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide.,dimethyl sulfoxide reductase complex,cellular_component
63269,GO:0009392,"Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.",N-acetyl-anhydromuramoyl-L-alanine amidase activity,molecular_function
63270,GO:0009394,"The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",2'-deoxyribonucleotide metabolic process,biological_process
63271,GO:0009395,"The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.",phospholipid catabolic process,biological_process
63272,GO:0009396,The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.,folic acid-containing compound biosynthetic process,biological_process
63273,GO:0009397,The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.,folic acid-containing compound catabolic process,biological_process
63274,GO:0009398,"The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.",FMN biosynthetic process,biological_process
63275,GO:0009399,"The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into ammonium, which is more biologically available.",nitrogen fixation,biological_process
63276,GO:0009401,"The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), ...",phosphoenolpyruvate-dependent sugar phosphotransferase system,biological_process
63277,GO:0009403,"The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.",toxin biosynthetic process,biological_process
63278,GO:0009404,"The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.",toxin metabolic process,biological_process
63279,GO:0009407,"The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.",toxin catabolic process,biological_process
63280,GO:0009408,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.",response to heat,biological_process
63281,GO:0009409,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.",response to cold,biological_process
63282,GO:0009410,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",response to xenobiotic stimulus,biological_process
63283,GO:0009411,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.",response to UV,biological_process
63284,GO:0009413,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.",response to flooding,biological_process
63285,GO:0009414,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.",response to water deprivation,biological_process
63286,GO:0009415,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.",response to water,biological_process
63287,GO:0009416,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.",response to light stimulus,biological_process
63288,GO:0009418,"The long, slender, mid section of a pilus.",pilus shaft,cellular_component
63289,GO:0009419,The pointed extremity furthest from the cell of a pilus.,pilus tip,cellular_component
63290,GO:0009420,"The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller.",bacterial-type flagellum filament,cellular_component
63291,GO:0009421,The proteinaceous structure at the distal tip of the bacterial-type flagellar filament.,bacterial-type flagellum filament cap,cellular_component
63292,GO:0009422,The region of the bacterial-type flagellum where the hook and filament meet.,bacterial-type flagellum hook-filament junction,cellular_component
63293,GO:0009423,The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.,chorismate biosynthetic process,biological_process
63294,GO:0009424,The portion of the bacterial-type flagellum that connects the filament to the basal body.,bacterial-type flagellum hook,cellular_component
63295,GO:0009425,"One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.",bacterial-type flagellum basal body,cellular_component
63296,GO:0009426,The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes.,"bacterial-type flagellum basal body, distal rod",cellular_component
63297,GO:0009427,One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane.,"bacterial-type flagellum basal body, distal rod, L ring",cellular_component
63298,GO:0009428,One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer.,"bacterial-type flagellum basal body, distal rod, P ring",cellular_component
63299,GO:0009429,The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor.,"bacterial-type flagellum basal body, proximal rod",cellular_component
63300,GO:0009431,One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane.,"bacterial-type flagellum basal body, MS ring",cellular_component
63301,GO:0009432,An error-prone process for repairing damaged microbial DNA.,SOS response,biological_process
63302,GO:0009433,"Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise.","bacterial-type flagellum basal body, C ring",cellular_component
63303,GO:0009435,"The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions. NAD+ is derived from various sources including vitamin B3.",NAD+ biosynthetic process,biological_process
63304,GO:0009436,"The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.",glyoxylate catabolic process,biological_process
63305,GO:0009437,"The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.",carnitine metabolic process,biological_process
63306,GO:0009438,"The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.",methylglyoxal metabolic process,biological_process
63307,GO:0009440,"The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.",cyanate catabolic process,biological_process
63308,GO:0009441,"The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).",glycolate metabolic process,biological_process
63309,GO:0009443,"Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.",pyridoxal 5'-phosphate salvage,biological_process
63310,GO:0009445,"The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.",putrescine metabolic process,biological_process
63311,GO:0009446,"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.",putrescine biosynthetic process,biological_process
63312,GO:0009447,"The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.",putrescine catabolic process,biological_process
63313,GO:0009449,"The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.",GABA biosynthetic process,biological_process
63314,GO:0009450,The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA).,GABA catabolic process,biological_process
63315,GO:0009451,The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.,RNA modification,biological_process
63316,GO:0009452,"The sequence of enzymatic reactions by which the RNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.",7-methylguanosine RNA capping,biological_process
63317,GO:0009453,"The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.",energy taxis,biological_process
63318,GO:0009454,The directed movement of a motile cell or organism in response to environmental oxygen.,aerotaxis,biological_process
63319,GO:0009455,The directed movement of a motile cell or organism in response to redox potential.,redox taxis,biological_process
63320,GO:0009486,Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].,cytochrome bo3 ubiquinol oxidase activity,molecular_function
63321,GO:0009496,Catalysis of the reaction: 2 H+[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H+[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane.,plastoquinol--plastocyanin reductase activity,molecular_function
63322,GO:0009501,A plastid whose main function is to synthesize and store starch.,amyloplast,cellular_component
63323,GO:0009503,"A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana.",thylakoid light-harvesting complex,cellular_component
63324,GO:0009504,The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equatorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.,cell plate,cellular_component
63325,GO:0009505,A more or less rigid structure lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.,plant-type cell wall,cellular_component
63326,GO:0009506,"A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.",plasmodesma,cellular_component
63327,GO:0009507,"A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.",chloroplast,cellular_component
63328,GO:0009508,A circular DNA molecule containing plastid encoded genes.,plastid chromosome,cellular_component
63329,GO:0009509,"A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.",chromoplast,cellular_component
63330,GO:0009510,"A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell.",plasmodesmatal desmotubule,cellular_component
63331,GO:0009511,"Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells.",plasmodesmatal endoplasmic reticulum,cellular_component
63332,GO:0009512,"Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.",cytochrome b6f complex,cellular_component
63333,GO:0009513,A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.,etioplast,cellular_component
63334,GO:0009514,"A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.",glyoxysome,cellular_component
63335,GO:0009515,Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II.,granal stacked thylakoid,cellular_component
63336,GO:0009516,A colorless plastid involved in the synthesis of monoterpenes.,leucoplast,cellular_component
63337,GO:0009517,Protein-pigment complex associated with photosystem II.,PSII associated light-harvesting complex II,cellular_component
63338,GO:0009518,Protein-pigment complex associated with photosystem I.,PSI associated light-harvesting complex I,cellular_component
63339,GO:0009519,"Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells.",middle lamella,cellular_component
63340,GO:0009521,A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species.,photosystem,cellular_component
63341,GO:0009522,"A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -...",photosystem I,cellular_component
63342,GO:0009523,"A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.",photosystem II,cellular_component
63343,GO:0009524,"The phragmoplast is a plant cell specific cytoplasmic structure composed of cytoskeletal polymers, membranes, and associated cytosolic proteins that functions as the focused secretory module for assembling the cell plate.",phragmoplast,cellular_component
63344,GO:0009525,A flattened membranous vesicle containing cell wall components.,phragmosome,cellular_component
63345,GO:0009526,The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,plastid envelope,cellular_component
63346,GO:0009527,"The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.",plastid outer membrane,cellular_component
63347,GO:0009528,"The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma.",plastid inner membrane,cellular_component
63348,GO:0009529,The region between the inner and outer lipid bilayers of the plastid envelope.,plastid intermembrane space,cellular_component
63349,GO:0009530,"A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present.",primary cell wall,cellular_component
63350,GO:0009531,A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.,secondary cell wall,cellular_component
63351,GO:0009532,The proteinaceous ground substance of plastids.,plastid stroma,cellular_component
63352,GO:0009533,Unstacked thylakoids that connect the grana stacks through the stroma.,chloroplast stromal thylakoid,cellular_component
63353,GO:0009534,Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.,chloroplast thylakoid,cellular_component
63354,GO:0009535,The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.,chloroplast thylakoid membrane,cellular_component
63355,GO:0009536,"Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.",plastid,cellular_component
63356,GO:0009537,The precursor of other plastids.,proplastid,cellular_component
63357,GO:0009538,"A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.",photosystem I reaction center,cellular_component
63358,GO:0009539,"An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone.",photosystem II reaction center,cellular_component
63359,GO:0009541,"A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast.",etioplast prolamellar body,cellular_component
63360,GO:0009542,"Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis.",granum,cellular_component
63361,GO:0009543,The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.,chloroplast thylakoid lumen,cellular_component
63362,GO:0009545,A leucoplast in which oil is stored.,elaioplast,cellular_component
63363,GO:0009546,The space between the plasma membrane and the desmotubule of a plasmodesma.,plasmodesmatal cytoplasmic sleeve,cellular_component
63364,GO:0009547,A ribosome contained within a plastid.,plastid ribosome,cellular_component
63365,GO:0009548,The portion of the plasma membrane surrounding a plasmodesma.,plasmodesmatal plasma membrane,cellular_component
63366,GO:0009549,"A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall m...",cellulose microfibril,cellular_component
63367,GO:0009550,"A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.",primary plasmodesma,cellular_component
63368,GO:0009551,"A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata.",secondary plasmodesma,cellular_component
63369,GO:0009553,"The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One ...",embryo sac development,biological_process
63370,GO:0009554,"The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.",megasporogenesis,biological_process
63371,GO:0009555,"The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately d...",pollen development,biological_process
63372,GO:0009556,"The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.",microsporogenesis,biological_process
63373,GO:0009557,The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.,antipodal cell differentiation,biological_process
63374,GO:0009558,"The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana.",embryo sac cellularization,biological_process
63375,GO:0009559,"The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.",embryo sac central cell differentiation,biological_process
63376,GO:0009560,The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.,embryo sac egg cell differentiation,biological_process
63377,GO:0009561,"The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrat...",megagametogenesis,biological_process
63378,GO:0009562,The directed movement of an embryo sac nucleus to the pole or center of the cell.,embryo sac nuclear migration,biological_process
63379,GO:0009563,The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.,synergid differentiation,biological_process
63380,GO:0009566,The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).,fertilization,biological_process
63381,GO:0009567,"Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.",double fertilization forming a zygote and endosperm,biological_process
63382,GO:0009568,"Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.",amyloplast starch grain,cellular_component
63383,GO:0009569,"Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.",chloroplast starch grain,cellular_component
63384,GO:0009570,"The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.",chloroplast stroma,cellular_component
63385,GO:0009571,The space enclosed by the double membrane of a proplastid.,proplastid stroma,cellular_component
63386,GO:0009573,"A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana.",chloroplast ribulose bisphosphate carboxylase complex,cellular_component
63387,GO:0009574,"A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.",preprophase band,cellular_component
63388,GO:0009575,The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material.,chromoplast stroma,cellular_component
63389,GO:0009576,The space enclosed by the double membrane of a leucoplast.,leucoplast stroma,cellular_component
63390,GO:0009577,The space enclosed by the double membrane of an elaioplast.,elaioplast stroma,cellular_component
63391,GO:0009578,The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA.,etioplast stroma,cellular_component
63392,GO:0009579,"A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the asso...",thylakoid,cellular_component
63393,GO:0009581,The series of events in which an external stimulus is received by a cell and converted into a molecular signal.,detection of external stimulus,biological_process
63394,GO:0009582,The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.,detection of abiotic stimulus,biological_process
63395,GO:0009583,The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.,detection of light stimulus,biological_process
63396,GO:0009584,"The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.",detection of visible light,biological_process
63397,GO:0009585,"The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.","red, far-red light phototransduction",biological_process
63398,GO:0009588,"The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm.","UV-A, blue light phototransduction",biological_process
63399,GO:0009589,The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.,detection of UV,biological_process
63400,GO:0009590,The series of events in which a gravitational stimulus is received and converted into a molecular signal.,detection of gravity,biological_process
63401,GO:0009593,The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.,detection of chemical stimulus,biological_process
63402,GO:0009594,The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal.,detection of nutrient,biological_process
63403,GO:0009595,"The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.",detection of biotic stimulus,biological_process
63404,GO:0009597,The series of events in which a stimulus from a virus is received and converted into a molecular signal.,detection of virus,biological_process
63405,GO:0009600,The series of events in which a stimulus from a nematode is received and converted into a molecular signal.,detection of nematode,biological_process
63406,GO:0009601,The series of events in which a stimulus from an insect is received and converted into a molecular signal.,detection of insect,biological_process
63407,GO:0009602,The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,detection of symbiont,biological_process
63408,GO:0009603,"The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal.",detection of symbiotic fungus,biological_process
63409,GO:0009604,"The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.",detection of symbiotic bacterium,biological_process
63410,GO:0009605,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.",response to external stimulus,biological_process
63411,GO:0009606,"The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.",tropism,biological_process
63412,GO:0009607,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.",response to biotic stimulus,biological_process
63413,GO:0009608,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.",response to symbiont,biological_process
63414,GO:0009609,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.",response to symbiotic bacterium,biological_process
63415,GO:0009610,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.",response to symbiotic fungus,biological_process
63416,GO:0009611,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.",response to wounding,biological_process
63417,GO:0009612,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.",response to mechanical stimulus,biological_process
63418,GO:0009615,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.",response to virus,biological_process
63419,GO:0009616,A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination.,RNAi-mediated antiviral immune response,biological_process
63420,GO:0009617,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.",response to bacterium,biological_process
63421,GO:0009620,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.",response to fungus,biological_process
63422,GO:0009624,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.",response to nematode,biological_process
63423,GO:0009625,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.",response to insect,biological_process
63424,GO:0009626,"The rapid, localized death of plant cells in response to invasion by a pathogen.",plant-type hypersensitive response,biological_process
63425,GO:0009627,The salicylic acid-mediated response to a pathogen which confers broad spectrum resistance.,systemic acquired resistance,biological_process
63426,GO:0009628,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.",response to abiotic stimulus,biological_process
63427,GO:0009629,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.",response to gravity,biological_process
63428,GO:0009630,The orientation of plant parts under the stimulation of gravity.,gravitropism,biological_process
63429,GO:0009631,"Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.",cold acclimation,biological_process
63430,GO:0009635,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.",response to herbicide,biological_process
63431,GO:0009636,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.",response to toxic substance,biological_process
63432,GO:0009637,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.",response to blue light,biological_process
63433,GO:0009638,"The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.",phototropism,biological_process
63434,GO:0009639,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon ex...",response to red or far red light,biological_process
63435,GO:0009640,"The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.",photomorphogenesis,biological_process
63436,GO:0009641,"Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytoc...",shade avoidance,biological_process
63437,GO:0009642,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.",response to light intensity,biological_process
63438,GO:0009643,A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.,photosynthetic acclimation,biological_process
63439,GO:0009644,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.",response to high light intensity,biological_process
63440,GO:0009645,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.",response to low light intensity stimulus,biological_process
63441,GO:0009646,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.",response to absence of light,biological_process
63442,GO:0009647,"The control of plant growth, development, and differentiation in response to growth in darkness.",skotomorphogenesis,biological_process
63443,GO:0009648,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.",photoperiodism,biological_process
63444,GO:0009649,The synchronization of a circadian rhythm to environmental time cues such as light.,entrainment of circadian clock,biological_process
63445,GO:0009650,"Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.",UV protection,biological_process
63446,GO:0009651,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",response to salt stress,biological_process
63447,GO:0009652,"The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.",thigmotropism,biological_process
63448,GO:0009653,The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.,anatomical structure morphogenesis,biological_process
63449,GO:0009654,"A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ).",photosystem II oxygen evolving complex,cellular_component
63450,GO:0009655,"The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.","PSII associated light-harvesting complex II, core complex",cellular_component
63451,GO:0009656,"Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light.","PSII associated light-harvesting complex II, peripheral complex",cellular_component
63452,GO:0009657,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.",plastid organization,biological_process
63453,GO:0009658,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.",chloroplast organization,biological_process
63454,GO:0009659,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.",leucoplast organization,biological_process
63455,GO:0009660,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.",amyloplast organization,biological_process
63456,GO:0009661,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.",chromoplast organization,biological_process
63457,GO:0009662,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.",etioplast organization,biological_process
63458,GO:0009663,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.",plasmodesma organization,biological_process
63459,GO:0009664,"A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.",plant-type cell wall organization,biological_process
63460,GO:0009665,The partitioning of plastids between daughter cells at cell division.,plastid inheritance,biological_process
63461,GO:0009666,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.",plastid outer membrane organization,biological_process
63462,GO:0009667,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.",plastid inner membrane organization,biological_process
63463,GO:0009668,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.",plastid membrane organization,biological_process
63464,GO:0009669,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in).,sucrose:monoatomic cation symporter activity,molecular_function
63465,GO:0009670,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out).,triose-phosphate:phosphate antiporter activity,molecular_function
63466,GO:0009671,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).,nitrate:proton symporter activity,molecular_function
63467,GO:0009672,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in).,auxin:proton symporter activity,molecular_function
63468,GO:0009673,Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity phosphate transmembrane transporter activity,molecular_function
63469,GO:0009674,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in).,potassium:sodium symporter activity,molecular_function
63470,GO:0009675,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity sulfate:proton symporter activity,molecular_function
63471,GO:0009676,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity sulfate:proton symporter activity,molecular_function
63472,GO:0009677,"Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.",double fertilization forming two zygotes,biological_process
63473,GO:0009678,Catalysis of the reaction: diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate.,diphosphate hydrolysis-driven proton transmembrane transporter activity,molecular_function
63474,GO:0009679,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).,hexose:proton symporter activity,molecular_function
63475,GO:0009682,A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.,induced systemic resistance,biological_process
63476,GO:0009684,"The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.",indoleacetic acid biosynthetic process,biological_process
63477,GO:0009685,The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.,gibberellin metabolic process,biological_process
63478,GO:0009686,The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.,gibberellin biosynthetic process,biological_process
63479,GO:0009687,"The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.",abscisic acid metabolic process,biological_process
63480,GO:0009688,"The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.",abscisic acid biosynthetic process,biological_process
63481,GO:0009690,"The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.",cytokinin metabolic process,biological_process
63482,GO:0009691,"The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.",cytokinin biosynthetic process,biological_process
63483,GO:0009692,"The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.",ethylene metabolic process,biological_process
63484,GO:0009693,"The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.",ethylene biosynthetic process,biological_process
63485,GO:0009694,"The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.",jasmonic acid metabolic process,biological_process
63486,GO:0009695,"The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.",jasmonic acid biosynthetic process,biological_process
63487,GO:0009696,"The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.",salicylic acid metabolic process,biological_process
63488,GO:0009697,"The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.",salicylic acid biosynthetic process,biological_process
63489,GO:0009698,The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.,phenylpropanoid metabolic process,biological_process
63490,GO:0009699,The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.,phenylpropanoid biosynthetic process,biological_process
63491,GO:0009700,"The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.",indole phytoalexin biosynthetic process,biological_process
63492,GO:0009701,"The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.",isoflavonoid phytoalexin biosynthetic process,biological_process
63493,GO:0009702,Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H+.,L-arabinokinase activity,molecular_function
63494,GO:0009703,Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.,nitrate reductase (NADH) activity,molecular_function
63495,GO:0009704,The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.,de-etiolation,biological_process
63496,GO:0009705,The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.,plant-type vacuole membrane,cellular_component
63497,GO:0009706,"The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.",chloroplast inner membrane,cellular_component
63498,GO:0009707,"The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope.",chloroplast outer membrane,cellular_component
63499,GO:0009708,"The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.",benzyl isoquinoline alkaloid biosynthetic process,biological_process
63500,GO:0009709,"The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).",terpenoid indole alkaloid biosynthetic process,biological_process
63501,GO:0009710,"The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.",tropane alkaloid biosynthetic process,biological_process
63502,GO:0009711,"The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.",purine alkaloid biosynthetic process,biological_process
63503,GO:0009712,"The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.",catechol-containing compound metabolic process,biological_process
63504,GO:0009713,The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.,catechol-containing compound biosynthetic process,biological_process
63505,GO:0009715,"The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.",chalcone biosynthetic process,biological_process
63506,GO:0009716,"The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.",flavonoid phytoalexin biosynthetic process,biological_process
63507,GO:0009717,"The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.",isoflavonoid biosynthetic process,biological_process
63508,GO:0009718,"The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.",anthocyanin-containing compound biosynthetic process,biological_process
63509,GO:0009719,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.",response to endogenous stimulus,biological_process
63510,GO:0009720,The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.,detection of hormone stimulus,biological_process
63511,GO:0009721,The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.,detection of auxin stimulus,biological_process
63512,GO:0009722,The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.,detection of cytokinin stimulus,biological_process
63513,GO:0009723,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.",response to ethylene,biological_process
63514,GO:0009724,The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal.,detection of abscisic acid stimulus,biological_process
63515,GO:0009725,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.",response to hormone,biological_process
63516,GO:0009727,The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.,detection of ethylene stimulus,biological_process
63517,GO:0009728,The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.,detection of gibberellic acid stimulus,biological_process
63518,GO:0009729,The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.,detection of brassinosteroid stimulus,biological_process
63519,GO:0009730,The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal.,detection of carbohydrate stimulus,biological_process
63520,GO:0009731,The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.,detection of sucrose stimulus,biological_process
63521,GO:0009732,The series of events in which a stimulus from a hexose is received and converted into a molecular signal.,detection of hexose stimulus,biological_process
63522,GO:0009733,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.",response to auxin,biological_process
63523,GO:0009734,"The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.",auxin-activated signaling pathway,biological_process
63524,GO:0009735,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.",response to cytokinin,biological_process
63525,GO:0009736,"The series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",cytokinin-activated signaling pathway,biological_process
63526,GO:0009737,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.",response to abscisic acid,biological_process
63527,GO:0009738,"The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.",abscisic acid-activated signaling pathway,biological_process
63528,GO:0009739,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.",response to gibberellin,biological_process
63529,GO:0009740,The series of molecular signals mediated by the detection of gibberellic acid.,gibberellic acid mediated signaling pathway,biological_process
63530,GO:0009741,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.",response to brassinosteroid,biological_process
63531,GO:0009742,The series of molecular signals mediated by the detection of brassinosteroid.,brassinosteroid mediated signaling pathway,biological_process
63532,GO:0009743,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.",response to carbohydrate,biological_process
63533,GO:0009744,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.",response to sucrose,biological_process
63534,GO:0009745,The series of molecular signals mediated by the detection of sucrose.,sucrose mediated signaling,biological_process
63535,GO:0009746,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.",response to hexose,biological_process
63536,GO:0009747,The series of molecular signals mediated by hexose and dependent on the detection of hexokinase.,hexokinase-dependent signaling,biological_process
63537,GO:0009748,The series of molecular signals mediated by hexose and independent of hexokinase.,hexokinase-independent signaling,biological_process
63538,GO:0009749,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.",response to glucose,biological_process
63539,GO:0009750,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.",response to fructose,biological_process
63540,GO:0009751,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.",response to salicylic acid,biological_process
63541,GO:0009752,The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.,detection of salicylic acid stimulus,biological_process
63542,GO:0009753,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.",response to jasmonic acid,biological_process
63543,GO:0009754,The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.,detection of jasmonic acid stimulus,biological_process
63544,GO:0009755,The series of molecular signals mediated by the detection of a hormone.,hormone-mediated signaling pathway,biological_process
63545,GO:0009756,The series of molecular signals mediated by the detection of carbohydrate.,carbohydrate mediated signaling,biological_process
63546,GO:0009757,The series of molecular signals mediated by the detection of hexose.,hexose mediated signaling,biological_process
63547,GO:0009758,"A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and e...",carbohydrate utilization,biological_process
63548,GO:0009759,"The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.",indole glucosinolate biosynthetic process,biological_process
63549,GO:0009760,"The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.",C4 photosynthesis,biological_process
63550,GO:0009761,"The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.",CAM photosynthesis,biological_process
63551,GO:0009762,"The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.",NADP-malic enzyme C4 photosynthesis,biological_process
63552,GO:0009763,"The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme.",NAD-malic enzyme C4 photosynthesis,biological_process
63553,GO:0009764,"The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).",PEP carboxykinase C4 photosynthesis,biological_process
63554,GO:0009765,Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.,"photosynthesis, light harvesting",biological_process
63555,GO:0009767,"A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.",photosynthetic electron transport chain,biological_process
63556,GO:0009768,"After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.","photosynthesis, light harvesting in photosystem I",biological_process
63557,GO:0009769,"After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.","photosynthesis, light harvesting in photosystem II",biological_process
63558,GO:0009772,"A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I.",photosynthetic electron transport in photosystem II,biological_process
63559,GO:0009773,"A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.",photosynthetic electron transport in photosystem I,biological_process
63560,GO:0009777,Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation.,photosynthetic phosphorylation,biological_process
63561,GO:0009778,A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.,cyclic photosynthetic phosphorylation,biological_process
63562,GO:0009779,A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II.,noncyclic photosynthetic phosphorylation,biological_process
63563,GO:0009782,"The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).",photosystem I antenna complex,cellular_component
63564,GO:0009783,"The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).",photosystem II antenna complex,cellular_component
63565,GO:0009784,Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.,transmembrane receptor histidine kinase activity,molecular_function
63566,GO:0009785,"The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.",blue light signaling pathway,biological_process
63567,GO:0009786,"Any process that modulates the frequency, rate or extent of asymmetric cell division.",regulation of asymmetric cell division,biological_process
63568,GO:0009787,"Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.",regulation of abscisic acid-activated signaling pathway,biological_process
63569,GO:0009788,"Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.",negative regulation of abscisic acid-activated signaling pathway,biological_process
63570,GO:0009789,"Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.",positive regulation of abscisic acid-activated signaling pathway,biological_process
63571,GO:0009790,"The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be ...",embryo development,biological_process
63572,GO:0009791,"The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.",post-embryonic development,biological_process
63573,GO:0009792,"The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.",embryo development ending in birth or egg hatching,biological_process
63574,GO:0009793,"The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.",embryo development ending in seed dormancy,biological_process
63575,GO:0009794,"Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.","regulation of mitotic cell cycle, embryonic",biological_process
63576,GO:0009798,"The establishment, maintenance and elaboration of a pattern along a line or around a point.",axis specification,biological_process
63577,GO:0009799,"The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.",specification of symmetry,biological_process
63578,GO:0009800,"The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.",cinnamic acid biosynthetic process,biological_process
63579,GO:0009801,"The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.",cinnamic acid ester metabolic process,biological_process
63580,GO:0009802,"The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.",cinnamic acid ester biosynthetic process,biological_process
63581,GO:0009803,"The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.",cinnamic acid metabolic process,biological_process
63582,GO:0009804,"The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.",coumarin metabolic process,biological_process
63583,GO:0009805,"The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.",coumarin biosynthetic process,biological_process
63584,GO:0009806,"The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.",lignan metabolic process,biological_process
63585,GO:0009807,"The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.",lignan biosynthetic process,biological_process
63586,GO:0009808,"The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.",lignin metabolic process,biological_process
63587,GO:0009809,"The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.",lignin biosynthetic process,biological_process
63588,GO:0009811,"The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.",stilbene biosynthetic process,biological_process
63589,GO:0009812,"The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.",flavonoid metabolic process,biological_process
63590,GO:0009813,"The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.",flavonoid biosynthetic process,biological_process
63591,GO:0009815,Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + dehydroascorbate + ethylene + 2 H2O + hydrogen cyanide. Ethene is also known as ethylene.,1-aminocyclopropane-1-carboxylate oxidase activity,molecular_function
63592,GO:0009819,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.",drought recovery,biological_process
63593,GO:0009820,"The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).",alkaloid metabolic process,biological_process
63594,GO:0009821,"The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).",alkaloid biosynthetic process,biological_process
63595,GO:0009822,"The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).",alkaloid catabolic process,biological_process
63596,GO:0009823,"The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.",cytokinin catabolic process,biological_process
63597,GO:0009824,Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.,AMP dimethylallyltransferase activity,molecular_function
63598,GO:0009825,The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.,multidimensional cell growth,biological_process
63599,GO:0009826,"The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.",unidimensional cell growth,biological_process
63600,GO:0009827,"The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.",plant-type cell wall modification,biological_process
63601,GO:0009828,The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.,plant-type cell wall loosening,biological_process
63602,GO:0009829,The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.,cell wall modification involved in fruit ripening,biological_process
63603,GO:0009830,A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.,cell wall modification involved in abscission,biological_process
63604,GO:0009831,The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.,plant-type cell wall modification involved in multidimensional cell growth,biological_process
63605,GO:0009832,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.",plant-type cell wall biogenesis,biological_process
63606,GO:0009833,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.",plant-type primary cell wall biogenesis,biological_process
63607,GO:0009834,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.",plant-type secondary cell wall biogenesis,biological_process
63608,GO:0009835,"An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.",fruit ripening,biological_process
63609,GO:0009836,A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.,"fruit ripening, climacteric",biological_process
63610,GO:0009837,A fruit ripening process that does not involve a respiratory burst.,"fruit ripening, non-climacteric",biological_process
63611,GO:0009838,The controlled shedding of a body part.,abscission,biological_process
63612,GO:0009840,A Clp endopeptidase complex located in the chloroplast.,chloroplastic endopeptidase Clp complex,cellular_component
63613,GO:0009841,A Clp endopeptidase complex located in the mitochondrion.,mitochondrial endopeptidase Clp complex,cellular_component
63614,GO:0009842,"A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.",cyanelle,cellular_component
63615,GO:0009843,"A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.",cyanelle thylakoid,cellular_component
63616,GO:0009845,The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.,seed germination,biological_process
63617,GO:0009846,"The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.",pollen germination,biological_process
63618,GO:0009847,The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).,spore germination,biological_process
63619,GO:0009850,"The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.",auxin metabolic process,biological_process
63620,GO:0009851,"The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.",auxin biosynthetic process,biological_process
63621,GO:0009852,"The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.",auxin catabolic process,biological_process
63622,GO:0009853,"A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination t...",photorespiration,biological_process
63623,GO:0009854,"The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).",oxidative photosynthetic carbon pathway,biological_process
63624,GO:0009855,"The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.",determination of bilateral symmetry,biological_process
63625,GO:0009856,"The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.",pollination,biological_process
63626,GO:0009859,The process in which water is taken up by pollen.,pollen hydration,biological_process
63627,GO:0009860,Growth of pollen via tip extension of the intine wall.,pollen tube growth,biological_process
63628,GO:0009861,The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.,jasmonic acid and ethylene-dependent systemic resistance,biological_process
63629,GO:0009862,The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.,"systemic acquired resistance, salicylic acid mediated signaling pathway",biological_process
63630,GO:0009863,The series of molecular signals mediated by salicylic acid.,salicylic acid mediated signaling pathway,biological_process
63631,GO:0009864,The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.,"induced systemic resistance, jasmonic acid mediated signaling pathway",biological_process
63632,GO:0009865,The process in which the pollen tube adheres to cells of the stigma and style.,pollen tube adhesion,biological_process
63633,GO:0009866,The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.,"induced systemic resistance, ethylene mediated signaling pathway",biological_process
63634,GO:0009867,The series of molecular signals mediated by jasmonic acid.,jasmonic acid mediated signaling pathway,biological_process
63635,GO:0009868,The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.,"jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway",biological_process
63636,GO:0009871,The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.,"jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway",biological_process
63637,GO:0009873,"The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.",ethylene-activated signaling pathway,biological_process
63638,GO:0009875,The interaction between a pollen grain and pistil.,pollen-pistil interaction,biological_process
63639,GO:0009876,The process in which pollen deposited on the stigma adheres to cells of the stigma.,pollen adhesion,biological_process
63640,GO:0009877,The formation of nitrogen-fixing root nodules on plant roots.,nodulation,biological_process
63641,GO:0009879,The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis.,determination of radial symmetry,biological_process
63642,GO:0009880,The process that results in the patterns of cell differentiation that will arise in an embryo.,embryonic pattern specification,biological_process
63643,GO:0009881,"The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.",photoreceptor activity,molecular_function
63644,GO:0009882,The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.,blue light photoreceptor activity,molecular_function
63645,GO:0009883,The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.,red or far-red light photoreceptor activity,molecular_function
63646,GO:0009884,Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,cytokinin receptor activity,molecular_function
63647,GO:0009885,Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.,transmembrane histidine kinase cytokinin receptor activity,molecular_function
63648,GO:0009886,"The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.",post-embryonic animal morphogenesis,biological_process
63649,GO:0009887,"Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",animal organ morphogenesis,biological_process
63650,GO:0009888,"The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.",tissue development,biological_process
63651,GO:0009889,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.",regulation of biosynthetic process,biological_process
63652,GO:0009890,"Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.",negative regulation of biosynthetic process,biological_process
63653,GO:0009891,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.",positive regulation of biosynthetic process,biological_process
63654,GO:0009892,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.",negative regulation of metabolic process,biological_process
63655,GO:0009893,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.",positive regulation of metabolic process,biological_process
63656,GO:0009894,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.",regulation of catabolic process,biological_process
63657,GO:0009895,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.",negative regulation of catabolic process,biological_process
63658,GO:0009896,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.",positive regulation of catabolic process,biological_process
63659,GO:0009897,"The leaflet of the plasma membrane that faces the extracellular side of the cell, including any protein embedded in, attached to, or peripherally associated with it.",external side of plasma membrane,cellular_component
63660,GO:0009898,"The leaflet of the plasma membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of plasma membrane,cellular_component
63661,GO:0009899,Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.,ent-kaurene synthase activity,molecular_function
63662,GO:0009900,"The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.",dehiscence,biological_process
63663,GO:0009901,The dehiscence of an anther to release the pollen grains contained within it.,anther dehiscence,biological_process
63664,GO:0009902,The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.,chloroplast relocation,biological_process
63665,GO:0009903,The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.,chloroplast avoidance movement,biological_process
63666,GO:0009904,The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.,chloroplast accumulation movement,biological_process
63667,GO:0009905,Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.,ent-copalyl diphosphate synthase activity,molecular_function
63668,GO:0009906,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.","response to photoperiod, blue light",biological_process
63669,GO:0009907,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.","response to photoperiod, red light",biological_process
63670,GO:0009908,"The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.",flower development,biological_process
63671,GO:0009909,"Any process that modulates the frequency, rate or extent of flower development.",regulation of flower development,biological_process
63672,GO:0009910,"Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.",negative regulation of flower development,biological_process
63673,GO:0009911,"Any process that activates or increases the frequency, rate or extent of flower development.",positive regulation of flower development,biological_process
63674,GO:0009912,The process in which the cellular identity of auditory hair cells is acquired and determined.,auditory receptor cell fate commitment,biological_process
63675,GO:0009913,"The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.",epidermal cell differentiation,biological_process
63676,GO:0009914,"The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hormone transport,biological_process
63677,GO:0009915,The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.,phloem sucrose loading,biological_process
63678,GO:0009916,"Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.",alternative oxidase activity,molecular_function
63679,GO:0009920,The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.,cell plate formation involved in plant-type cell wall biogenesis,biological_process
63680,GO:0009921,"The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.",auxin efflux carrier complex,cellular_component
63681,GO:0009922,Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.,fatty acid elongase activity,molecular_function
63682,GO:0009923,A tetrameric complex of four different subunits which catalyzes the elongation of a fatty acid chain 2 carbon units at a time in the synthesis of very long chain fatty acids.,fatty acid elongase complex,cellular_component
63683,GO:0009925,"The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.",basal plasma membrane,cellular_component
63684,GO:0009926,The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.,auxin polar transport,biological_process
63685,GO:0009927,Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.,histidine phosphotransfer kinase activity,molecular_function
63686,GO:0009930,The side of the cell parallel to the zygotic axis.,longitudinal side of cell surface,cellular_component
63687,GO:0009931,Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.,calcium-dependent protein serine/threonine kinase activity,molecular_function
63688,GO:0009932,Growth that occurs specifically at the tip of a cell.,cell tip growth,biological_process
63689,GO:0009933,"Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.",meristem structural organization,biological_process
63690,GO:0009934,"Any process that modulates the frequency, rate or extent of meristem organization.",regulation of meristem structural organization,biological_process
63691,GO:0009937,"Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.",regulation of gibberellic acid mediated signaling pathway,biological_process
63692,GO:0009938,"Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.",negative regulation of gibberellic acid mediated signaling pathway,biological_process
63693,GO:0009939,"Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.",positive regulation of gibberellic acid mediated signaling pathway,biological_process
63694,GO:0009941,The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,chloroplast envelope,cellular_component
63695,GO:0009942,"The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.",longitudinal axis specification,biological_process
63696,GO:0009943,"The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.",adaxial/abaxial axis specification,biological_process
63697,GO:0009944,The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.,polarity specification of adaxial/abaxial axis,biological_process
63698,GO:0009945,"The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.",radial axis specification,biological_process
63699,GO:0009946,"The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).",proximal/distal axis specification,biological_process
63700,GO:0009947,"The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.",centrolateral axis specification,biological_process
63701,GO:0009948,"The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.",anterior/posterior axis specification,biological_process
63702,GO:0009949,Any process resulting in the establishment of polarity along the anterior/posterior axis.,polarity specification of anterior/posterior axis,biological_process
63703,GO:0009950,"The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.",dorsal/ventral axis specification,biological_process
63704,GO:0009951,Any process resulting in the establishment of polarity along the dorsal/ventral axis.,polarity specification of dorsal/ventral axis,biological_process
63705,GO:0009952,The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.,anterior/posterior pattern specification,biological_process
63706,GO:0009953,The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.,dorsal/ventral pattern formation,biological_process
63707,GO:0009954,The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).,proximal/distal pattern formation,biological_process
63708,GO:0009955,The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.,adaxial/abaxial pattern specification,biological_process
63709,GO:0009956,The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.,radial pattern formation,biological_process
63710,GO:0009957,"The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",epidermal cell fate specification,biological_process
63711,GO:0009958,The orientation of plant parts towards gravity.,positive gravitropism,biological_process
63712,GO:0009959,The orientation of plant parts away from gravity.,negative gravitropism,biological_process
63713,GO:0009960,"The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.",endosperm development,biological_process
63714,GO:0009961,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.",response to 1-aminocyclopropane-1-carboxylic acid,biological_process
63715,GO:0009962,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.",regulation of flavonoid biosynthetic process,biological_process
63716,GO:0009963,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.",positive regulation of flavonoid biosynthetic process,biological_process
63717,GO:0009964,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.",negative regulation of flavonoid biosynthetic process,biological_process
63718,GO:0009965,The process in which the anatomical structures of the leaf are generated and organized.,leaf morphogenesis,biological_process
63719,GO:0009966,"Any process that modulates the frequency, rate or extent of signal transduction.",regulation of signal transduction,biological_process
63720,GO:0009967,"Any process that activates or increases the frequency, rate or extent of signal transduction.",positive regulation of signal transduction,biological_process
63721,GO:0009968,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.",negative regulation of signal transduction,biological_process
63722,GO:0009969,"The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.",xyloglucan biosynthetic process,biological_process
63723,GO:0009970,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.",cellular response to sulfate starvation,biological_process
63724,GO:0009971,"The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.",anastral spindle assembly involved in male meiosis,biological_process
63725,GO:0009973,Catalysis of the reaction: A + AMP + 2 H+ + sulfite = adenosine 5'-phosphosulfate + AH2.,adenylyl-sulfate reductase activity,molecular_function
63726,GO:0009975,Catalysis of a ring closure reaction.,cyclase activity,molecular_function
63727,GO:0009976,"Catalysis of the reactions: delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol, gamma-tocopherol = 2,3-dimethyl-6-phytylbenzene-1,4-diol. delta-tocotrienol = 6-geranylgeranyl-2-methylbenzene-1,4-diol gamma-tocotrienol, and = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol.",tocopherol cyclase activity,molecular_function
63728,GO:0009977,Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane.,proton motive force dependent protein transmembrane transporter activity,molecular_function
63729,GO:0009978,"Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.",allene oxide synthase activity,molecular_function
63730,GO:0009982,Catalysis of the reaction: a uridine in RNA = a pseudouridine in RNA. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.,pseudouridine synthase activity,molecular_function
63731,GO:0009986,The external part of the cell wall and/or plasma membrane.,cell surface,cellular_component
63732,GO:0009987,"Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",cellular process,biological_process
63733,GO:0009988,Cell recognition between cells. May involve the formation of specialized cell junctions.,cell-cell recognition,biological_process
63734,GO:0009989,Cell recognition that involves the interaction of the cell with the extracellular matrix.,cell-matrix recognition,biological_process
63735,GO:0009990,Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.,contact guidance,biological_process
63736,GO:0009992,A homeostatic process involved in the maintenance of a steady state level of water within a cell.,intracellular water homeostasis,biological_process
63737,GO:0009994,The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.,oocyte differentiation,biological_process
63738,GO:0009995,The recognition of soluble molecules in the environment.,soluble molecule recognition,biological_process
63739,GO:0009996,"Any process that restricts, stops or prevents a cell from adopting a specific cell fate.",negative regulation of cell fate specification,biological_process
63740,GO:0009997,"Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",negative regulation of cardioblast cell fate specification,biological_process
63741,GO:0009998,"Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.",negative regulation of retinal cone cell fate specification,biological_process
63742,GO:0009999,"Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.",negative regulation of auditory receptor cell fate specification,biological_process
63743,GO:0010001,The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.,glial cell differentiation,biological_process
63744,GO:0010002,"The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast differentiation,biological_process
63745,GO:0010004,"A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.",gastrulation involving germ band extension,biological_process
63746,GO:0010005,"Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.","cortical microtubule, transverse to long axis",cellular_component
63747,GO:0010006,Protein translocon complex at the chloroplast outer membrane.,Toc complex,cellular_component
63748,GO:0010007,"A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.",magnesium chelatase complex,cellular_component
63749,GO:0010008,The lipid bilayer surrounding an endosome.,endosome membrane,cellular_component
63750,GO:0010009,"The leaflet of the endosome membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of endosome membrane,cellular_component
63751,GO:0010011,"Binding to auxin, a plant hormone that regulates aspects of plant growth.",auxin binding,molecular_function
63752,GO:0010013,"Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.",N-1-naphthylphthalamic acid binding,molecular_function
63753,GO:0010014,"Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.",meristem initiation,biological_process
63754,GO:0010015,"The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.",root morphogenesis,biological_process
63755,GO:0010016,The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.,shoot system morphogenesis,biological_process
63756,GO:0010017,"The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption ...",red or far-red light signaling pathway,biological_process
63757,GO:0010018,"The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reverse...",far-red light signaling pathway,biological_process
63758,GO:0010019,"The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.",chloroplast-nucleus signaling pathway,biological_process
63759,GO:0010020,The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.,chloroplast fission,biological_process
63760,GO:0010021,"The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.",amylopectin biosynthetic process,biological_process
63761,GO:0010022,The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).,meristem determinacy,biological_process
63762,GO:0010023,The chemical reactions and pathways resulting in the formation of proanthocyanidin.,proanthocyanidin biosynthetic process,biological_process
63763,GO:0010024,"The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.",phytochromobilin biosynthetic process,biological_process
63764,GO:0010025,"The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.",wax biosynthetic process,biological_process
63765,GO:0010026,The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.,trichome differentiation,biological_process
63766,GO:0010027,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.",thylakoid membrane organization,biological_process
63767,GO:0010028,"A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.",xanthophyll cycle,biological_process
63768,GO:0010029,"Any process that modulates the frequency, rate or extent of seed germination.",regulation of seed germination,biological_process
63769,GO:0010030,Any process that activates or increase the rate of seed germination.,positive regulation of seed germination,biological_process
63770,GO:0010031,The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.,circumnutation,biological_process
63771,GO:0010032,Compaction of chromatin structure prior to meiosis in eukaryotic cells.,meiotic chromosome condensation,biological_process
63772,GO:0010034,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.",response to acetate,biological_process
63773,GO:0010036,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.",response to boron-containing substance,biological_process
63774,GO:0010037,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.",response to carbon dioxide,biological_process
63775,GO:0010038,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.",response to metal ion,biological_process
63776,GO:0010039,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.",response to iron ion,biological_process
63777,GO:0010040,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.",response to iron(II) ion,biological_process
63778,GO:0010041,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.",response to iron(III) ion,biological_process
63779,GO:0010042,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.",response to manganese ion,biological_process
63780,GO:0010043,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.",response to zinc ion,biological_process
63781,GO:0010044,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.",response to aluminum ion,biological_process
63782,GO:0010045,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.",response to nickel cation,biological_process
63783,GO:0010046,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.",response to mycotoxin,biological_process
63784,GO:0010047,The process leading to the spontaneous opening of the fruit permitting the escape of seeds.,fruit dehiscence,biological_process
63785,GO:0010048,The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.,vernalization response,biological_process
63786,GO:0010049,The process in which a plant acquires the ability to respond to a floral inductive signal.,acquisition of plant reproductive competence,biological_process
63787,GO:0010050,Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.,vegetative phase change,biological_process
63788,GO:0010051,The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.,xylem and phloem pattern formation,biological_process
63789,GO:0010052,The process in which a guard mother cell acquires the specialized features of a guard cell.,guard cell differentiation,biological_process
63790,GO:0010053,The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.,root epidermal cell differentiation,biological_process
63791,GO:0010054,"The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.",trichoblast differentiation,biological_process
63792,GO:0010055,"The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.",atrichoblast differentiation,biological_process
63793,GO:0010056,The process involved in the specification of an atrichoblast.,atrichoblast fate specification,biological_process
63794,GO:0010057,The process involved in the specification of a trichoblast.,trichoblast fate specification,biological_process
63795,GO:0010058,Any process that modulates atrichoblast fate specification.,regulation of atrichoblast fate specification,biological_process
63796,GO:0010059,Any process that induces or promotes atrichoblast fate specification.,positive regulation of atrichoblast fate specification,biological_process
63797,GO:0010060,Any process that suppresses atrichoblast fate specification.,negative regulation of atrichoblast fate specification,biological_process
63798,GO:0010061,Any process that modulates trichoblast fate specification.,regulation of trichoblast fate specification,biological_process
63799,GO:0010062,Any process that suppresses trichoblast fate specification.,negative regulation of trichoblast fate specification,biological_process
63800,GO:0010063,Any process that induces or promotes trichoblast fate specification.,positive regulation of trichoblast fate specification,biological_process
63801,GO:0010064,The process in which the anatomical structures of embryonic shoot are generated and organized.,embryonic shoot morphogenesis,biological_process
63802,GO:0010065,"The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.",primary meristem tissue development,biological_process
63803,GO:0010066,The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.,ground meristem histogenesis,biological_process
63804,GO:0010067,The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.,procambium histogenesis,biological_process
63805,GO:0010068,The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.,protoderm histogenesis,biological_process
63806,GO:0010069,The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.,zygote asymmetric cytokinesis in embryo sac,biological_process
63807,GO:0010070,The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.,zygote asymmetric cell division,biological_process
63808,GO:0010071,The specification of a meristem which will give rise to a primary or lateral root.,root meristem specification,biological_process
63809,GO:0010072,"The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.",primary shoot apical meristem specification,biological_process
63810,GO:0010073,"Any process involved in maintaining the identity, size and shape of a meristem.",meristem maintenance,biological_process
63811,GO:0010074,"The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of meristem identity,biological_process
63812,GO:0010075,Any process involved in maintaining the size and shape of a meristem.,regulation of meristem growth,biological_process
63813,GO:0010076,"The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of floral meristem identity,biological_process
63814,GO:0010077,"The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of inflorescence meristem identity,biological_process
63815,GO:0010078,"The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of root meristem identity,biological_process
63816,GO:0010079,"The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of vegetative meristem identity,biological_process
63817,GO:0010080,Any process involved in maintaining the size and shape of a floral meristem.,regulation of floral meristem growth,biological_process
63818,GO:0010081,Any process involved in maintaining the size and shape of an inflorescence meristem.,regulation of inflorescence meristem growth,biological_process
63819,GO:0010082,Any process involved in maintaining the size and shape of a root meristem.,regulation of root meristem growth,biological_process
63820,GO:0010083,Any process involved in maintaining the size and shape of a vegetative meristem.,regulation of vegetative meristem growth,biological_process
63821,GO:0010084,The process in which the polarity of an animal organ axis is specified.,specification of animal organ axis polarity,biological_process
63822,GO:0010085,Any process resulting in the establishment of polarity along the proximal/distal axis.,polarity specification of proximal/distal axis,biological_process
63823,GO:0010086,The process in which the anatomical structures of the embryonic root are generated and organized.,embryonic root morphogenesis,biological_process
63824,GO:0010087,"The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.",phloem or xylem histogenesis,biological_process
63825,GO:0010088,The formation of the principal food-conducting tissue of a vascular plant.,phloem development,biological_process
63826,GO:0010089,The formation of the principal water-conducting tissue of a vascular plant.,xylem development,biological_process
63827,GO:0010090,The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.,trichome morphogenesis,biological_process
63828,GO:0010091,Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.,trichome branching,biological_process
63829,GO:0010092,The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of animal organ identity,biological_process
63830,GO:0010093,The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of floral organ identity,biological_process
63831,GO:0010094,The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of carpel identity,biological_process
63832,GO:0010095,The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of petal identity,biological_process
63833,GO:0010096,The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of sepal identity,biological_process
63834,GO:0010097,The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of stamen identity,biological_process
63835,GO:0010098,"The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.",suspensor development,biological_process
63836,GO:0010099,Any process that modulates the rate or extent of photomorphogenesis.,regulation of photomorphogenesis,biological_process
63837,GO:0010100,"Any process that stops, reduces or prevents photomorphogenesis.",negative regulation of photomorphogenesis,biological_process
63838,GO:0010101,The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.,post-embryonic root morphogenesis,biological_process
63839,GO:0010102,"The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.",lateral root morphogenesis,biological_process
63840,GO:0010103,The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.,stomatal complex morphogenesis,biological_process
63841,GO:0010104,"Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction.",regulation of ethylene-activated signaling pathway,biological_process
63842,GO:0010105,Any process that stops or prevents ethylene (ethene) signal transduction.,negative regulation of ethylene-activated signaling pathway,biological_process
63843,GO:0010106,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.",cellular response to iron ion starvation,biological_process
63844,GO:0010109,"Any process that modulates the frequency, rate or extent of photosynthesis.",regulation of photosynthesis,biological_process
63845,GO:0010110,"Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.","regulation of photosynthesis, dark reaction",biological_process
63846,GO:0010111,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.",glyoxysome organization,biological_process
63847,GO:0010112,"Any process that modulates the frequency, rate or extent of systemic acquired resistance.",regulation of systemic acquired resistance,biological_process
63848,GO:0010113,"Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.",negative regulation of systemic acquired resistance,biological_process
63849,GO:0010114,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response...",response to red light,biological_process
63850,GO:0010115,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.",regulation of abscisic acid biosynthetic process,biological_process
63851,GO:0010116,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.",positive regulation of abscisic acid biosynthetic process,biological_process
63852,GO:0010117,Protection mechanism used by plants and cyanobacteria under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.,photoprotection,biological_process
63853,GO:0010118,"The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).",stomatal movement,biological_process
63854,GO:0010119,"Any process that modulates the frequency, rate or extent of stomatal movement.",regulation of stomatal movement,biological_process
63855,GO:0010120,"The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.",camalexin biosynthetic process,biological_process
63856,GO:0010124,The chemical reactions and pathways resulting in the breakdown of phenylacetate.,phenylacetate catabolic process,biological_process
63857,GO:0010125,"The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.",mycothiol biosynthetic process,biological_process
63858,GO:0010126,"The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.",mycothiol metabolic process,biological_process
63859,GO:0010127,The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.,mycothiol-dependent detoxification,biological_process
63860,GO:0010129,"The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, an alicyclic acid.",cyclohexane-1-carboxylate catabolic process,biological_process
63861,GO:0010130,"The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.",anaerobic ethylbenzene catabolic process,biological_process
63862,GO:0010132,"The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.",dhurrin biosynthetic process,biological_process
63863,GO:0010136,"The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.",ureide catabolic process,biological_process
63864,GO:0010137,"The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.",ureide biosynthetic process,biological_process
63865,GO:0010138,The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.,pyrimidine ribonucleotide salvage,biological_process
63866,GO:0010139,The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.,pyrimidine deoxyribonucleotide salvage,biological_process
63867,GO:0010143,"The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.",cutin biosynthetic process,biological_process
63868,GO:0010146,The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.,fructan biosynthetic process,biological_process
63869,GO:0010147,"The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.",fructan catabolic process,biological_process
63870,GO:0010148,Release of water by the plant into the air as water vapor mainly through leaves.,transpiration,biological_process
63871,GO:0010150,The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place.,leaf senescence,biological_process
63872,GO:0010151,Expansion of the chloroplast that usually precedes division.,chloroplast elongation,biological_process
63873,GO:0010152,The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.,pollen maturation,biological_process
63874,GO:0010154,"The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.",fruit development,biological_process
63875,GO:0010155,"Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of proton transport,biological_process
63876,GO:0010157,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.",response to chlorate,biological_process
63877,GO:0010158,"The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",abaxial cell fate specification,biological_process
63878,GO:0010159,The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ.,specification of animal organ position,biological_process
63879,GO:0010160,The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.,formation of animal organ boundary,biological_process
63880,GO:0010161,"The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by ...",red light signaling pathway,biological_process
63881,GO:0010162,"A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.",seed dormancy process,biological_process
63882,GO:0010164,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.",response to cesium ion,biological_process
63883,GO:0010165,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).",response to X-ray,biological_process
63884,GO:0010166,"The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.",wax metabolic process,biological_process
63885,GO:0010167,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.",response to nitrate,biological_process
63886,GO:0010168,A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.,ER body,cellular_component
63887,GO:0010169,"A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.",thioglucosidase complex,cellular_component
63888,GO:0010170,"Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.",glucose-1-phosphate adenylyltransferase complex,cellular_component
63889,GO:0010171,The process in which the anatomical structures of the soma are generated and organized.,body morphogenesis,biological_process
63890,GO:0010172,The process in which the anatomical structures of the embryonic soma are generated and organized.,embryonic body morphogenesis,biological_process
63891,GO:0010174,"Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.","nucleoside transmembrane transporter activity, against a concentration gradient",molecular_function
63892,GO:0010176,"Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.",homogentisate phytyltransferase activity,molecular_function
63893,GO:0010177,Catalysis of the reaction: acetyl-CoA + an omega-(methylsulfanyl)-2-oxoalkanoate + H2O = a 2-(omega-methylsulfanyl)alkylmalate + CoA + H+.,methylthioalkylmalate synthase activity,molecular_function
63894,GO:0010178,Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.,IAA-amino acid conjugate hydrolase activity,molecular_function
63895,GO:0010179,Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.,IAA-Ala conjugate hydrolase activity,molecular_function
63896,GO:0010180,Binding to a thioglucosidase enzyme.,thioglucosidase binding,molecular_function
63897,GO:0010181,Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.,FMN binding,molecular_function
63898,GO:0010182,"The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.",sugar mediated signaling pathway,biological_process
63899,GO:0010183,The process in which the growth of pollen tube is directed towards the female gametophyte.,pollen tube guidance,biological_process
63900,GO:0010184,"The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cytokinin transport,biological_process
63901,GO:0010185,"Any process that modulates the frequency, rate or extent of cellular defense response.",regulation of cellular defense response,biological_process
63902,GO:0010186,"Any process that activates or increases the frequency, rate or extent of cellular defense response.",positive regulation of cellular defense response,biological_process
63903,GO:0010187,"Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.",negative regulation of seed germination,biological_process
63904,GO:0010188,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.",response to microbial phytotoxin,biological_process
63905,GO:0010189,"The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.",vitamin E biosynthetic process,biological_process
63906,GO:0010190,"Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.",cytochrome b6f complex assembly,biological_process
63907,GO:0010192,"The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.",mucilage biosynthetic process,biological_process
63908,GO:0010193,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.",response to ozone,biological_process
63909,GO:0010196,"The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.",nonphotochemical quenching,biological_process
63910,GO:0010197,"The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.",polar nucleus fusion,biological_process
63911,GO:0010198,"Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.",synergid death,biological_process
63912,GO:0010199,The process in which boundaries between lateral organs and the meristem is established and maintained.,organ boundary specification between lateral organs and the meristem,biological_process
63913,GO:0010200,"A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.",response to chitin,biological_process
63914,GO:0010201,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.",response to continuous far red light stimulus by the high-irradiance response system,biological_process
63915,GO:0010202,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.",response to low fluence red light stimulus,biological_process
63916,GO:0010203,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.",response to very low fluence red light stimulus,biological_process
63917,GO:0010205,The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.,photoinhibition,biological_process
63918,GO:0010206,Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.,photosystem II repair,biological_process
63919,GO:0010207,"The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.",photosystem II assembly,biological_process
63920,GO:0010208,"The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.",pollen wall assembly,biological_process
63921,GO:0010209,"Binding to a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.",vacuolar sorting signal receptor activity,molecular_function
63922,GO:0010210,Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.,IAA-Phe conjugate hydrolase activity,molecular_function
63923,GO:0010211,Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.,IAA-Leu conjugate hydrolase activity,molecular_function
63924,GO:0010212,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.",response to ionizing radiation,biological_process
63925,GO:0010213,A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.,non-photoreactive DNA repair,biological_process
63926,GO:0010214,"The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.",seed coat development,biological_process
63927,GO:0010215,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.",cellulose microfibril organization,biological_process
63928,GO:0010218,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in respo...",response to far red light,biological_process
63929,GO:0010219,"Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.",regulation of vernalization response,biological_process
63930,GO:0010220,"Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.",positive regulation of vernalization response,biological_process
63931,GO:0010221,"Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.",negative regulation of vernalization response,biological_process
63932,GO:0010222,Vascular tissue pattern formation as it occurs in the stem of vascular plants.,stem vascular tissue pattern formation,biological_process
63933,GO:0010223,The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initiating the development of lateral organs.,secondary shoot formation,biological_process
63934,GO:0010224,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.",response to UV-B,biological_process
63935,GO:0010225,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.",response to UV-C,biological_process
63936,GO:0010226,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.",response to lithium ion,biological_process
63937,GO:0010227,The controlled shedding of floral organs.,floral organ abscission,biological_process
63938,GO:0010228,"The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.",vegetative to reproductive phase transition of meristem,biological_process
63939,GO:0010229,"The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.",inflorescence development,biological_process
63940,GO:0010230,"Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.",alternative respiration,biological_process
63941,GO:0010231,Any process that maintains a seed in a dormant state.,maintenance of seed dormancy,biological_process
63942,GO:0010232,"The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.",vascular transport,biological_process
63943,GO:0010233,"The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues.",phloem transport,biological_process
63944,GO:0010234,"The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",anther wall tapetum cell fate specification,biological_process
63945,GO:0010235,The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.,guard mother cell cytokinesis,biological_process
63946,GO:0010236,"The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.",plastoquinone biosynthetic process,biological_process
63947,GO:0010238,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.",response to proline,biological_process
63948,GO:0010239,Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.,chloroplast mRNA processing,biological_process
63949,GO:0010242,Catalysis of the reaction: 2 a plastoquinone + 4 hnu + 2 H2O = 2 a plastoquinol + O2. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants.,oxygen evolving activity,molecular_function
63950,GO:0010244,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the tr...",response to low fluence blue light stimulus by blue low-fluence system,biological_process
63951,GO:0010245,Formation of radial microtubular systems during male meiotic cytokinesis in plants.,radial microtubular system formation,biological_process
63952,GO:0010246,"The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.",rhamnogalacturonan I biosynthetic process,biological_process
63953,GO:0010247,The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.,detection of phosphate ion,biological_process
63954,GO:0010248,The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.,establishment or maintenance of transmembrane electrochemical gradient,biological_process
63955,GO:0010249,"The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.",auxin conjugate metabolic process,biological_process
63956,GO:0010250,"The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.",S-methylmethionine biosynthetic process,biological_process
63957,GO:0010253,"The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.",UDP-rhamnose biosynthetic process,biological_process
63958,GO:0010254,"The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.",nectary development,biological_process
63959,GO:0010255,The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.,glucose mediated signaling pathway,biological_process
63960,GO:0010256,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.",endomembrane system organization,biological_process
63961,GO:0010257,"The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.",NADH dehydrogenase complex assembly,biological_process
63962,GO:0010258,"The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.",NADH dehydrogenase complex (plastoquinone) assembly,biological_process
63963,GO:0010262,"Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.",somatic embryogenesis,biological_process
63964,GO:0010263,"The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.",tricyclic triterpenoid biosynthetic process,biological_process
63965,GO:0010264,"The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.",myo-inositol hexakisphosphate biosynthetic process,biological_process
63966,GO:0010265,"The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.",SCF complex assembly,biological_process
63967,GO:0010266,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.",response to vitamin B1,biological_process
63968,GO:0010267,A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs.,ta-siRNA processing,biological_process
63969,GO:0010268,Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.,brassinosteroid homeostasis,biological_process
63970,GO:0010269,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.",response to selenium ion,biological_process
63971,GO:0010270,"The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.",photosystem II oxygen evolving complex assembly,biological_process
63972,GO:0010271,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.",regulation of chlorophyll catabolic process,biological_process
63973,GO:0010272,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.",response to silver ion,biological_process
63974,GO:0010273,Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.,detoxification of copper ion,biological_process
63975,GO:0010274,"Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.",hydrotropism,biological_process
63976,GO:0010275,"The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.",NAD(P)H dehydrogenase complex assembly,biological_process
63977,GO:0010276,Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.,phytol kinase activity,molecular_function
63978,GO:0010277,Catalysis of the reactions: chlorophyllide a + 2 H+ + 2 NADPH + 2 O2 = chlorophyllide b + 3 H2O + 2 NADP+.,chlorophyllide a oxygenase activity,molecular_function
63979,GO:0010278,"The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.",chloroplast outer membrane translocon,cellular_component
63980,GO:0010279,Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.,indole-3-acetic acid amido synthetase activity,molecular_function
63981,GO:0010280,Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.,UDP-L-rhamnose synthase activity,molecular_function
63982,GO:0010282,A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.,senescence-associated vacuole,cellular_component
63983,GO:0010283,Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.,pinoresinol reductase activity,molecular_function
63984,GO:0010284,Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.,lariciresinol reductase activity,molecular_function
63985,GO:0010285,"Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H+.","L,L-diaminopimelate:2-oxoglutarate transaminase activity",molecular_function
63986,GO:0010286,Any process that increases heat tolerance of an organism in response to high temperatures.,heat acclimation,biological_process
63987,GO:0010287,"A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.",plastoglobule,cellular_component
63988,GO:0010288,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.",response to lead ion,biological_process
63989,GO:0010289,"The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.",homogalacturonan biosynthetic process,biological_process
63990,GO:0010290,"Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other.",chlorophyll catabolite transmembrane transporter activity,molecular_function
63991,GO:0010291,Catalysis of the reaction: all-trans-beta-carotene + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-zeaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].,beta-carotene 3-hydroxylase activity,molecular_function
63992,GO:0010292,Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).,GTP:GDP antiporter activity,molecular_function
63993,GO:0010293,Catalysis of the reaction: a 2-cis-(+)-abscisic aldehyde + H2O + O2 = 2-cis-(+)-abscisate + H+ + H2O2.,abscisic aldehyde oxidase activity,molecular_function
63994,GO:0010294,Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.,abscisic acid glucosyltransferase activity,molecular_function
63995,GO:0010295,Catalysis of the reaction: (+)-abscisate + H+ + NADPH + O2 = (+)-8'-hydroxyabscisate + H2O + NADP+.,(+)-abscisic acid 8'-hydroxylase activity,molecular_function
63996,GO:0010296,Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.,prenylcysteine methylesterase activity,molecular_function
63997,GO:0010297,"Binding to a heteropolysaccharide, a glycan composed of more than one type of monosaccharide residue.",heteropolysaccharide binding,molecular_function
63998,GO:0010298,Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.,dihydrocamalexic acid decarboxylase activity,molecular_function
63999,GO:0010299,Any process that reduces or removes the toxicity of cobalt ion (Co2+). These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.,detoxification of cobalt ion,biological_process
64000,GO:0010301,Catalysis of the reaction: NAD+ + xanthoxin = (+)-abscisic aldehyde + H+ + NADH.,xanthoxin dehydrogenase (NAD+) activity,molecular_function
64001,GO:0010303,"Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.",limit dextrinase activity,molecular_function
64002,GO:0010304,The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.,PSII associated light-harvesting complex II catabolic process,biological_process
64003,GO:0010305,Vascular tissue pattern formation as it occurs in the leaf of vascular plants.,leaf vascular tissue pattern formation,biological_process
64004,GO:0010306,"The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.",rhamnogalacturonan II biosynthetic process,biological_process
64005,GO:0010307,Binds to and modulates the activity of acetylglutamate kinase.,acetylglutamate kinase regulator activity,molecular_function
64006,GO:0010308,"Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + CO + formate.",acireductone dioxygenase (Ni2+-requiring) activity,molecular_function
64007,GO:0010309,"Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-methylthio-2-oxobutanoate + formate + H+.",acireductone dioxygenase [iron(II)-requiring] activity,molecular_function
64008,GO:0010310,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.",regulation of hydrogen peroxide metabolic process,biological_process
64009,GO:0010311,"The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.",lateral root formation,biological_process
64010,GO:0010312,Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.,detoxification of zinc ion,biological_process
64011,GO:0010313,Binding to a phytochrome.,phytochrome binding,molecular_function
64012,GO:0010314,"Binding to phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.",phosphatidylinositol-5-phosphate binding,molecular_function
64013,GO:0010315,"The directed movement of auxins from inside of a cell, across the plasma membrane and into the extracellular region.",auxin export across the plasma membrane,biological_process
64014,GO:0010316,"Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.",pyrophosphate-dependent phosphofructokinase complex,cellular_component
64015,GO:0010317,Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.,"pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex",cellular_component
64016,GO:0010318,Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.,"pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex",cellular_component
64017,GO:0010319,"Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. O...",stromule,cellular_component
64018,GO:0010321,"Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.",regulation of vegetative phase change,biological_process
64019,GO:0010322,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).","regulation of isopentenyl diphosphate biosynthetic process, methylerythritol phosphate pathway",biological_process
64020,GO:0010323,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).","negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol phosphate pathway",biological_process
64021,GO:0010324,The infolding of a membrane.,membrane invagination,biological_process
64022,GO:0010325,"The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).",raffinose family oligosaccharide biosynthetic process,biological_process
64023,GO:0010326,Catalysis of the reaction: a 2-oxocarboxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid.,L-methionine:oxo-acid transaminase activity,molecular_function
64024,GO:0010327,Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.,acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity,molecular_function
64025,GO:0010328,"Enables the transfer of auxin, from one side of a membrane to the other, into a cell.",auxin influx transmembrane transporter activity,molecular_function
64026,GO:0010329,"Enables the transfer of auxin, from one side of a membrane to the other, out of a cell.",auxin efflux transmembrane transporter activity,molecular_function
64027,GO:0010330,"A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.",cellulose synthase complex,cellular_component
64028,GO:0010331,"Binding to a gibberellin, a plant hormone that regulates aspects of plant growth.",gibberellin binding,molecular_function
64029,GO:0010332,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and ener...",response to gamma radiation,biological_process
64030,GO:0010333,"Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.",terpene synthase activity,molecular_function
64031,GO:0010334,"Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.",sesquiterpene synthase activity,molecular_function
64032,GO:0010335,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.",response to non-ionic osmotic stress,biological_process
64033,GO:0010336,"Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.",gibberellic acid homeostasis,biological_process
64034,GO:0010337,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.",regulation of salicylic acid metabolic process,biological_process
64035,GO:0010338,The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.,leaf formation,biological_process
64036,GO:0010339,The side of the cell wall that is opposite to the side that faces the cell and its contents.,external side of cell wall,cellular_component
64037,GO:0010340,Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.,carboxyl-O-methyltransferase activity,molecular_function
64038,GO:0010341,Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.,gibberellin carboxyl-O-methyltransferase activity,molecular_function
64039,GO:0010342,"The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.",endosperm cellularization,biological_process
64040,GO:0010343,Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.,singlet oxygen-mediated programmed cell death,biological_process
64041,GO:0010344,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.",seed oilbody biogenesis,biological_process
64042,GO:0010345,The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.,suberin biosynthetic process,biological_process
64043,GO:0010346,The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.,shoot axis formation,biological_process
64044,GO:0010347,Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.,L-galactose-1-phosphate phosphatase activity,molecular_function
64045,GO:0010348,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).,lithium:proton antiporter activity,molecular_function
64046,GO:0010349,"Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.",L-galactose dehydrogenase activity,molecular_function
64047,GO:0010350,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.",cellular response to magnesium starvation,biological_process
64048,GO:0010351,"The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lithium ion transport,biological_process
64049,GO:0010352,The directed movement of lithium ion out of a cell or organelle.,lithium ion export across the plasma membrane,biological_process
64050,GO:0010353,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.",response to trehalose,biological_process
64051,GO:0010354,Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.,homogentisate prenyltransferase activity,molecular_function
64052,GO:0010355,Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.,homogentisate farnesyltransferase activity,molecular_function
64053,GO:0010356,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + H+ + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate.",homogentisate geranylgeranyltransferase activity,molecular_function
64054,GO:0010357,"Catalysis of the reaction: all-trans-nonaprenyl diphosphate + H+ + homogentisate = 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.",homogentisate solanesyltransferase activity,molecular_function
64055,GO:0010358,The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.,leaf shaping,biological_process
64056,GO:0010360,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.",negative regulation of anion channel activity,biological_process
64057,GO:0010363,"Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.",regulation of plant-type hypersensitive response,biological_process
64058,GO:0010364,"Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.",regulation of ethylene biosynthetic process,biological_process
64059,GO:0010365,"Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.",positive regulation of ethylene biosynthetic process,biological_process
64060,GO:0010366,"Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.",negative regulation of ethylene biosynthetic process,biological_process
64061,GO:0010367,"A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.",extracellular isoamylase complex,cellular_component
64062,GO:0010368,"A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.",chloroplast isoamylase complex,cellular_component
64063,GO:0010369,"A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure.",chromocenter,cellular_component
64064,GO:0010370,A chromocenter adjacent to the nucleolus.,perinucleolar chromocenter,cellular_component
64065,GO:0010371,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.",regulation of gibberellin biosynthetic process,biological_process
64066,GO:0010372,"Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.",positive regulation of gibberellin biosynthetic process,biological_process
64067,GO:0010373,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.",negative regulation of gibberellin biosynthetic process,biological_process
64068,GO:0010374,The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.,stomatal complex development,biological_process
64069,GO:0010375,The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.,stomatal complex patterning,biological_process
64070,GO:0010376,The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.,stomatal complex formation,biological_process
64071,GO:0010377,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.",guard cell fate commitment,biological_process
64072,GO:0010378,"The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.",temperature compensation of the circadian clock,biological_process
64073,GO:0010379,"The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).",phaseic acid biosynthetic process,biological_process
64074,GO:0010380,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.",regulation of chlorophyll biosynthetic process,biological_process
64075,GO:0010383,The chemical reactions and pathways involving cell wall polysaccharides.,cell wall polysaccharide metabolic process,biological_process
64076,GO:0010384,"The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.",cell wall proteoglycan metabolic process,biological_process
64077,GO:0010385,Binding to double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.,double-stranded methylated DNA binding,molecular_function
64078,GO:0010387,"The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.",COP9 signalosome assembly,biological_process
64079,GO:0010389,Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.,regulation of G2/M transition of mitotic cell cycle,biological_process
64080,GO:0010391,"The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.",glucomannan metabolic process,biological_process
64081,GO:0010392,"The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.",galactoglucomannan metabolic process,biological_process
64082,GO:0010393,"The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.",galacturonan metabolic process,biological_process
64083,GO:0010394,"The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.",homogalacturonan metabolic process,biological_process
64084,GO:0010395,"The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.",rhamnogalacturonan I metabolic process,biological_process
64085,GO:0010398,"The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.",xylogalacturonan metabolic process,biological_process
64086,GO:0010400,"The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.",rhamnogalacturonan I side chain metabolic process,biological_process
64087,GO:0010401,"The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.",pectic galactan metabolic process,biological_process
64088,GO:0010405,"The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Al...",arabinogalactan protein metabolic process,biological_process
64089,GO:0010406,"The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.",classical arabinogalactan protein metabolic process,biological_process
64090,GO:0010407,"The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.",non-classical arabinogalactan protein metabolic process,biological_process
64091,GO:0010411,"The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.",xyloglucan metabolic process,biological_process
64092,GO:0010412,"The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.",mannan metabolic process,biological_process
64093,GO:0010413,"The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.",glucuronoxylan metabolic process,biological_process
64094,GO:0010417,"The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.",glucuronoxylan biosynthetic process,biological_process
64095,GO:0010420,"Catalysis of the reaction: a 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine = a 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-homocysteine + H+.",polyprenyldihydroxybenzoate methyltransferase activity,molecular_function
64096,GO:0010421,Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.,hydrogen peroxide-mediated programmed cell death,biological_process
64097,GO:0010422,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.",regulation of brassinosteroid biosynthetic process,biological_process
64098,GO:0010423,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.",negative regulation of brassinosteroid biosynthetic process,biological_process
64099,GO:0010427,"Binding to abscisic acid, a plant hormone that regulates aspects of plant growth.",abscisic acid binding,molecular_function
64100,GO:0010428,Binding to a methylated cytosine/unspecified/guanine trinucleotide.,methyl-CpNpG binding,molecular_function
64101,GO:0010429,Binding to a methylated cytosine/unspecified/unspecified trinucleotide.,methyl-CpNpN binding,molecular_function
64102,GO:0010430,"A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.",fatty acid omega-oxidation,biological_process
64103,GO:0010431,"A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.",seed maturation,biological_process
64104,GO:0010432,"The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.",bract development,biological_process
64105,GO:0010433,"The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.",bract morphogenesis,biological_process
64106,GO:0010434,"The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.",bract formation,biological_process
64107,GO:0010436,Catalysis of the oxidative cleavage of carotenoids.,carotenoid dioxygenase activity,molecular_function
64108,GO:0010437,"Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.","9,10 (9', 10')-carotenoid-cleaving dioxygenase activity",molecular_function
64109,GO:0010438,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.",cellular response to sulfur starvation,biological_process
64110,GO:0010439,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.",regulation of glucosinolate biosynthetic process,biological_process
64111,GO:0010440,The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.,stomatal lineage progression,biological_process
64112,GO:0010441,"The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.",guard cell development,biological_process
64113,GO:0010442,Generation and organization of the polarized cell that is capable of turgor driven movement.,guard cell morphogenesis,biological_process
64114,GO:0010443,The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.,meristemoid mother cell division,biological_process
64115,GO:0010444,The process in which a meristemoid acquires the specialized features of a guard mother cell.,guard mother cell differentiation,biological_process
64116,GO:0010445,"A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.",nuclear dicing body,cellular_component
64117,GO:0010446,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.",response to alkaline pH,biological_process
64118,GO:0010447,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.",response to acidic pH,biological_process
64119,GO:0010448,"The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.",vegetative meristem growth,biological_process
64120,GO:0010449,"The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.",root meristem growth,biological_process
64121,GO:0010450,"The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.",inflorescence meristem growth,biological_process
64122,GO:0010451,"The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.",floral meristem growth,biological_process
64123,GO:0010453,"Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.",regulation of cell fate commitment,biological_process
64124,GO:0010454,"Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.",negative regulation of cell fate commitment,biological_process
64125,GO:0010455,"Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.",positive regulation of cell fate commitment,biological_process
64126,GO:0010456,"The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.",cell proliferation in dorsal spinal cord,biological_process
64127,GO:0010457,The cell cycle process in which the two centrioles within a centrosome remain tightly paired.,centriole-centriole cohesion,biological_process
64128,GO:0010458,The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.,exit from mitosis,biological_process
64129,GO:0010459,"Any process that stops, prevents or reduces the frequency or rate of heart contraction.",negative regulation of heart rate,biological_process
64130,GO:0010460,Any process that activates or increases the frequency or rate of heart contraction.,positive regulation of heart rate,biological_process
64131,GO:0010461,Enables the transmembrane transfer of a monoatomic ion by a channel that opens in response to a light stimulus.,light-activated monoatomic ion channel activity,molecular_function
64132,GO:0010463,"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.",mesenchymal cell proliferation,biological_process
64133,GO:0010464,"Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.",regulation of mesenchymal cell proliferation,biological_process
64134,GO:0010465,"Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.",nerve growth factor receptor activity,molecular_function
64135,GO:0010466,"Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.",negative regulation of peptidase activity,biological_process
64136,GO:0010467,"The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.",gene expression,biological_process
64137,GO:0010468,"Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).",regulation of gene expression,biological_process
64138,GO:0010469,"Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.",regulation of signaling receptor activity,biological_process
64139,GO:0010470,Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.,regulation of gastrulation,biological_process
64140,GO:0010471,Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + beta-L-galactose-1-phosphate.,GDP-galactose:mannose-1-phosphate guanylyltransferase activity,molecular_function
64141,GO:0010472,Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-glucose 1-phosphate = beta-L-galactose-1-phosphate + GDP-alpha-D-glucose.,GDP-galactose:glucose-1-phosphate guanylyltransferase activity,molecular_function
64142,GO:0010473,Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.,GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity,molecular_function
64143,GO:0010476,The series of molecular signals generated as a consequence of gibberellin stimulus.,gibberellin mediated signaling pathway,biological_process
64144,GO:0010477,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.",response to sulfur dioxide,biological_process
64145,GO:0010478,A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.,chlororespiration,biological_process
64146,GO:0010479,"The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.",stele development,biological_process
64147,GO:0010480,"The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.",microsporocyte differentiation,biological_process
64148,GO:0010481,"Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.",epidermal cell division,biological_process
64149,GO:0010482,"Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.",regulation of epidermal cell division,biological_process
64150,GO:0010483,"An interaction between the pollen tube, part of the male gametophyte, and the female gametophyte (typically the synergid cells), that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.",pollen tube reception,biological_process
64151,GO:0010484,Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.,histone H3 acetyltransferase activity,molecular_function
64152,GO:0010485,Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.,histone H4 acetyltransferase activity,molecular_function
64153,GO:0010486,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).,manganese:proton antiporter activity,molecular_function
64154,GO:0010487,Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.,thermospermine synthase activity,molecular_function
64155,GO:0010488,"Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.","UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity",molecular_function
64156,GO:0010489,Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.,"UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity",molecular_function
64157,GO:0010490,Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.,UDP-4-keto-rhamnose-4-keto-reductase activity,molecular_function
64158,GO:0010491,Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.,UTP:arabinose-1-phosphate uridylyltransferase activity,molecular_function
64159,GO:0010492,"The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.",maintenance of shoot apical meristem identity,biological_process
64160,GO:0010493,"The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.",Lewis a epitope biosynthetic process,biological_process
64161,GO:0010494,A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.,cytoplasmic stress granule,cellular_component
64162,GO:0010495,"An siRNA-mediated posttranscriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs, and in which the silencing signal originates in one tissue and occurs in a different tissue.",siRNA-mediated long-distance post-transcriptional gene silencing,biological_process
64163,GO:0010496,The movement of substances between cells.,intercellular transport,biological_process
64164,GO:0010497,"The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.",plasmodesmata-mediated intercellular transport,biological_process
64165,GO:0010498,The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.,proteasomal protein catabolic process,biological_process
64166,GO:0010499,The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.,proteasomal ubiquitin-independent protein catabolic process,biological_process
64167,GO:0010500,"The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.",transmitting tissue development,biological_process
64168,GO:0010506,"Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.",regulation of autophagy,biological_process
64169,GO:0010507,"Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.",negative regulation of autophagy,biological_process
64170,GO:0010508,"Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.",positive regulation of autophagy,biological_process
64171,GO:0010509,A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell.,intracellular polyamine homeostasis,biological_process
64172,GO:0010510,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.",regulation of pyruvate decarboxylation to acetyl-CoA,biological_process
64173,GO:0010511,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.",regulation of phosphatidylinositol biosynthetic process,biological_process
64174,GO:0010512,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.",negative regulation of phosphatidylinositol biosynthetic process,biological_process
64175,GO:0010513,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.",positive regulation of phosphatidylinositol biosynthetic process,biological_process
64176,GO:0010516,"Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.",negative regulation of cellular response to nitrogen starvation,biological_process
64177,GO:0010517,"Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.",regulation of phospholipase activity,biological_process
64178,GO:0010518,"Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.",positive regulation of phospholipase activity,biological_process
64179,GO:0010520,"Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.",regulation of reciprocal meiotic recombination,biological_process
64180,GO:0010521,"Binds to and stops, prevents or reduces the activity of telomerase.",telomerase inhibitor activity,molecular_function
64181,GO:0010522,Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.,regulation of calcium ion transport into cytosol,biological_process
64182,GO:0010523,Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.,negative regulation of calcium ion transport into cytosol,biological_process
64183,GO:0010524,Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.,positive regulation of calcium ion transport into cytosol,biological_process
64184,GO:0010526,"Any process that decreases the frequency, rate or extent of transposable element expression. Includes both DNA transposons and retrotransposons.",transposable element silencing,biological_process
64185,GO:0010540,"The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.",basipetal auxin transport,biological_process
64186,GO:0010541,"The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.",acropetal auxin transport,biological_process
64187,GO:0010542,Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.,nitrate efflux transmembrane transporter activity,molecular_function
64188,GO:0010543,"Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.",regulation of platelet activation,biological_process
64189,GO:0010544,"Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.",negative regulation of platelet activation,biological_process
64190,GO:0010547,The controlled breakdown of the thylakoid membrane in the context of a normal process.,thylakoid membrane disassembly,biological_process
64191,GO:0010548,"Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.",regulation of thylakoid membrane disassembly,biological_process
64192,GO:0010549,"Any process that modulates the frequency, rate or extent of membrane disassembly.",regulation of membrane disassembly,biological_process
64193,GO:0010550,Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.,regulation of PSII associated light-harvesting complex II catabolic process,biological_process
64194,GO:0010555,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.",response to mannitol,biological_process
64195,GO:0010556,"Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",regulation of macromolecule biosynthetic process,biological_process
64196,GO:0010557,"Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",positive regulation of macromolecule biosynthetic process,biological_process
64197,GO:0010558,"Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",negative regulation of macromolecule biosynthetic process,biological_process
64198,GO:0010559,"Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",regulation of glycoprotein biosynthetic process,biological_process
64199,GO:0010560,"Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",positive regulation of glycoprotein biosynthetic process,biological_process
64200,GO:0010561,"Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.",negative regulation of glycoprotein biosynthetic process,biological_process
64201,GO:0010562,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.",positive regulation of phosphorus metabolic process,biological_process
64202,GO:0010563,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.",negative regulation of phosphorus metabolic process,biological_process
64203,GO:0010564,Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.,regulation of cell cycle process,biological_process
64204,GO:0010565,"Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.",regulation of ketone metabolic process,biological_process
64205,GO:0010566,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.",regulation of ketone biosynthetic process,biological_process
64206,GO:0010567,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.",regulation of ketone catabolic process,biological_process
64207,GO:0010568,"Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.",regulation of budding cell apical bud growth,biological_process
64208,GO:0010569,"Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.",regulation of double-strand break repair via homologous recombination,biological_process
64209,GO:0010570,"Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.",regulation of filamentous growth,biological_process
64210,GO:0010571,"Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.",positive regulation of nuclear cell cycle DNA replication,biological_process
64211,GO:0010572,"Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.",positive regulation of platelet activation,biological_process
64212,GO:0010573,"The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",vascular endothelial growth factor production,biological_process
64213,GO:0010574,"Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.",regulation of vascular endothelial growth factor production,biological_process
64214,GO:0010575,"Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.",positive regulation of vascular endothelial growth factor production,biological_process
64215,GO:0010581,"An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.",regulation of starch biosynthetic process,biological_process
64216,GO:0010582,The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).,floral meristem determinacy,biological_process
64217,GO:0010583,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.",response to cyclopentenone,biological_process
64218,GO:0010584,"The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.",pollen exine formation,biological_process
64219,GO:0010585,The controlled release of glutamine by a cell.,L-glutamine secretion,biological_process
64220,GO:0010586,"The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.",miRNA metabolic process,biological_process
64221,GO:0010587,"The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.",miRNA catabolic process,biological_process
64222,GO:0010588,Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.,cotyledon vascular tissue pattern formation,biological_process
64223,GO:0010589,The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.,leaf proximal/distal pattern formation,biological_process
64224,GO:0010590,"Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.",regulation of septum digestion after cytokinesis,biological_process
64225,GO:0010591,"Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.",regulation of lamellipodium assembly,biological_process
64226,GO:0010592,"Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.",positive regulation of lamellipodium assembly,biological_process
64227,GO:0010593,"Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.",negative regulation of lamellipodium assembly,biological_process
64228,GO:0010594,"Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.",regulation of endothelial cell migration,biological_process
64229,GO:0010595,"Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.",positive regulation of endothelial cell migration,biological_process
64230,GO:0010596,"Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.",negative regulation of endothelial cell migration,biological_process
64231,GO:0010597,"The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.",green leaf volatile biosynthetic process,biological_process
64232,GO:0010598,"Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.",NAD(P)H dehydrogenase complex (plastoquinone),cellular_component
64233,GO:0010599,A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.,lsiRNA processing,biological_process
64234,GO:0010600,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.",regulation of auxin biosynthetic process,biological_process
64235,GO:0010601,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.",positive regulation of auxin biosynthetic process,biological_process
64236,GO:0010603,"Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.",regulation of cytoplasmic mRNA processing body assembly,biological_process
64237,GO:0010604,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",positive regulation of macromolecule metabolic process,biological_process
64238,GO:0010605,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",negative regulation of macromolecule metabolic process,biological_process
64239,GO:0010606,"Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.",positive regulation of cytoplasmic mRNA processing body assembly,biological_process
64240,GO:0010607,"Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.",negative regulation of cytoplasmic mRNA processing body assembly,biological_process
64241,GO:0010608,"Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.",post-transcriptional regulation of gene expression,biological_process
64242,GO:0010609,"Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintenance in, a specific location within the cell.",mRNA localization resulting in post-transcriptional regulation of gene expression,biological_process
64243,GO:0010610,Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.,regulation of mRNA stability involved in response to stress,biological_process
64244,GO:0010611,"Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.",regulation of cardiac muscle hypertrophy,biological_process
64245,GO:0010612,"Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.",regulation of cardiac muscle adaptation,biological_process
64246,GO:0010613,"Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.",positive regulation of cardiac muscle hypertrophy,biological_process
64247,GO:0010614,"Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.",negative regulation of cardiac muscle hypertrophy,biological_process
64248,GO:0010615,"Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.",positive regulation of cardiac muscle adaptation,biological_process
64249,GO:0010616,"Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.",negative regulation of cardiac muscle adaptation,biological_process
64250,GO:0010617,Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.,circadian regulation of calcium ion oscillation,biological_process
64251,GO:0010618,"The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.",aerenchyma formation,biological_process
64252,GO:0010619,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by glucose binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway,biological_process
64253,GO:0010620,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",negative regulation of transcription by transcription factor catabolism,biological_process
64254,GO:0010622,The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of ovule identity,biological_process
64255,GO:0010623,The activation of endogenous cellular processes that result in the death of a cell as part of its development.,programmed cell death involved in cell development,biological_process
64256,GO:0010624,"Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.",regulation of Schwann cell proliferation,biological_process
64257,GO:0010625,"Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.",positive regulation of Schwann cell proliferation,biological_process
64258,GO:0010626,"Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.",negative regulation of Schwann cell proliferation,biological_process
64259,GO:0010628,"Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).",positive regulation of gene expression,biological_process
64260,GO:0010629,"Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).",negative regulation of gene expression,biological_process
64261,GO:0010630,"Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.","regulation of transcription, start site selection",biological_process
64262,GO:0010631,"The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.",epithelial cell migration,biological_process
64263,GO:0010632,"Any process that modulates the frequency, rate or extent of epithelial cell migration.",regulation of epithelial cell migration,biological_process
64264,GO:0010633,"Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.",negative regulation of epithelial cell migration,biological_process
64265,GO:0010634,"Any process that activates or increases the frequency, rate or extent of epithelial cell migration.",positive regulation of epithelial cell migration,biological_process
64266,GO:0010635,"Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.",regulation of mitochondrial fusion,biological_process
64267,GO:0010636,"Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.",positive regulation of mitochondrial fusion,biological_process
64268,GO:0010637,"Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.",negative regulation of mitochondrial fusion,biological_process
64269,GO:0010638,"Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.",positive regulation of organelle organization,biological_process
64270,GO:0010639,"Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.",negative regulation of organelle organization,biological_process
64271,GO:0010640,"Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.",regulation of platelet-derived growth factor receptor signaling pathway,biological_process
64272,GO:0010641,"Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.",positive regulation of platelet-derived growth factor receptor signaling pathway,biological_process
64273,GO:0010642,"Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.",negative regulation of platelet-derived growth factor receptor signaling pathway,biological_process
64274,GO:0010643,"The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.",cell communication by chemical coupling,biological_process
64275,GO:0010644,The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.,cell communication by electrical coupling,biological_process
64276,GO:0010645,"Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.",regulation of cell communication by chemical coupling,biological_process
64277,GO:0010646,"Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",regulation of cell communication,biological_process
64278,GO:0010647,"Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",positive regulation of cell communication,biological_process
64279,GO:0010648,"Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",negative regulation of cell communication,biological_process
64280,GO:0010649,"Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.",regulation of cell communication by electrical coupling,biological_process
64281,GO:0010650,"Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.",positive regulation of cell communication by electrical coupling,biological_process
64282,GO:0010651,"Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.",negative regulation of cell communication by electrical coupling,biological_process
64283,GO:0010652,"Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.",positive regulation of cell communication by chemical coupling,biological_process
64284,GO:0010653,"Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.",negative regulation of cell communication by chemical coupling,biological_process
64285,GO:0010654,The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.,apical cell fate commitment,biological_process
64286,GO:0010656,"Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.",negative regulation of muscle cell apoptotic process,biological_process
64287,GO:0010657,"A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.",muscle cell apoptotic process,biological_process
64288,GO:0010658,"A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.",striated muscle cell apoptotic process,biological_process
64289,GO:0010659,"A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.",cardiac muscle cell apoptotic process,biological_process
64290,GO:0010660,"Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.",regulation of muscle cell apoptotic process,biological_process
64291,GO:0010661,"Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.",positive regulation of muscle cell apoptotic process,biological_process
64292,GO:0010662,"Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.",regulation of striated muscle cell apoptotic process,biological_process
64293,GO:0010663,"Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.",positive regulation of striated muscle cell apoptotic process,biological_process
64294,GO:0010664,"Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.",negative regulation of striated muscle cell apoptotic process,biological_process
64295,GO:0010665,"Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.",regulation of cardiac muscle cell apoptotic process,biological_process
64296,GO:0010666,"Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.",positive regulation of cardiac muscle cell apoptotic process,biological_process
64297,GO:0010667,"Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.",negative regulation of cardiac muscle cell apoptotic process,biological_process
64298,GO:0010668,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.,ectodermal cell differentiation,biological_process
64299,GO:0010669,A tissue homeostatic process required for the maintenance of epithelial structure.,epithelial structure maintenance,biological_process
64300,GO:0010684,"The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.",tricyclic triterpenoid catabolic process,biological_process
64301,GO:0010686,"The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.",tetracyclic triterpenoid biosynthetic process,biological_process
64302,GO:0010688,"Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.",negative regulation of ribosomal protein gene transcription by RNA polymerase II,biological_process
64303,GO:0010689,"Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.",negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus,biological_process
64304,GO:0010690,"Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.",negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress,biological_process
64305,GO:0010691,"Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.",negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels,biological_process
64306,GO:0010694,"Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.",positive regulation of alkaline phosphatase activity,biological_process
64307,GO:0010695,"Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.",regulation of mitotic spindle pole body separation,biological_process
64308,GO:0010696,"Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.",positive regulation of mitotic spindle pole body separation,biological_process
64309,GO:0010697,"Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.",negative regulation of mitotic spindle pole body separation,biological_process
64310,GO:0010698,"Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.",acetyltransferase activator activity,molecular_function
64311,GO:0010700,"Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.",negative regulation of norepinephrine secretion,biological_process
64312,GO:0010701,"Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.",positive regulation of norepinephrine secretion,biological_process
64313,GO:0010705,The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.,meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,biological_process
64314,GO:0010709,The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.,heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing,biological_process
64315,GO:0010710,"Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.",regulation of collagen catabolic process,biological_process
64316,GO:0010711,"Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.",negative regulation of collagen catabolic process,biological_process
64317,GO:0010712,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",regulation of collagen metabolic process,biological_process
64318,GO:0010713,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",negative regulation of collagen metabolic process,biological_process
64319,GO:0010714,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",positive regulation of collagen metabolic process,biological_process
64320,GO:0010715,"Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.",regulation of extracellular matrix disassembly,biological_process
64321,GO:0010716,"Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.",negative regulation of extracellular matrix disassembly,biological_process
64322,GO:0010717,"Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",regulation of epithelial to mesenchymal transition,biological_process
64323,GO:0010718,"Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",positive regulation of epithelial to mesenchymal transition,biological_process
64324,GO:0010719,"Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",negative regulation of epithelial to mesenchymal transition,biological_process
64325,GO:0010720,"Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",positive regulation of cell development,biological_process
64326,GO:0010721,"Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",negative regulation of cell development,biological_process
64327,GO:0010724,"Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.",regulation of definitive erythrocyte differentiation,biological_process
64328,GO:0010725,"Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.",regulation of primitive erythrocyte differentiation,biological_process
64329,GO:0010727,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.",negative regulation of hydrogen peroxide metabolic process,biological_process
64330,GO:0010728,"Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.",regulation of hydrogen peroxide biosynthetic process,biological_process
64331,GO:0010729,"Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.",positive regulation of hydrogen peroxide biosynthetic process,biological_process
64332,GO:0010730,"Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.",negative regulation of hydrogen peroxide biosynthetic process,biological_process
64333,GO:0010731,The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.,protein glutathionylation,biological_process
64334,GO:0010732,"Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.",regulation of protein glutathionylation,biological_process
64335,GO:0010733,"Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.",positive regulation of protein glutathionylation,biological_process
64336,GO:0010734,"Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.",negative regulation of protein glutathionylation,biological_process
64337,GO:0010736,"Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.",serum response element binding,molecular_function
64338,GO:0010742,"The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",macrophage derived foam cell differentiation,biological_process
64339,GO:0010743,"Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",regulation of macrophage derived foam cell differentiation,biological_process
64340,GO:0010744,"Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",positive regulation of macrophage derived foam cell differentiation,biological_process
64341,GO:0010745,"Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",negative regulation of macrophage derived foam cell differentiation,biological_process
64342,GO:0010746,"Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",regulation of long-chain fatty acid import across plasma membrane,biological_process
64343,GO:0010747,"Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",positive regulation of long-chain fatty acid import across plasma membrane,biological_process
64344,GO:0010748,"Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.",negative regulation of long-chain fatty acid import across plasma membrane,biological_process
64345,GO:0010754,"Any process that decreases the rate, frequency or extent of receptor guanylyl cyclase signaling pathway.",negative regulation of receptor guanylyl cyclase signaling pathway,biological_process
64346,GO:0010755,"Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.",regulation of plasminogen activation,biological_process
64347,GO:0010756,"Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.",positive regulation of plasminogen activation,biological_process
64348,GO:0010757,"Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.",negative regulation of plasminogen activation,biological_process
64349,GO:0010758,"Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.",regulation of macrophage chemotaxis,biological_process
64350,GO:0010759,"Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.",positive regulation of macrophage chemotaxis,biological_process
64351,GO:0010760,"Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.",negative regulation of macrophage chemotaxis,biological_process
64352,GO:0010761,Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.,fibroblast migration,biological_process
64353,GO:0010762,"Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.",regulation of fibroblast migration,biological_process
64354,GO:0010763,"Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.",positive regulation of fibroblast migration,biological_process
64355,GO:0010764,"Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.",negative regulation of fibroblast migration,biological_process
64356,GO:0010765,"Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of sodium ion transport,biological_process
64357,GO:0010766,"Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of sodium ion transport,biological_process
64358,GO:0010770,"Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.",positive regulation of cell morphogenesis,biological_process
64359,GO:0010771,"Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.",negative regulation of cell morphogenesis,biological_process
64360,GO:0010772,"The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.",meiotic DNA recombinase assembly involved in reciprocal meiotic recombination,biological_process
64361,GO:0010774,The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.,meiotic strand invasion involved in reciprocal meiotic recombination,biological_process
64362,GO:0010777,"A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.",meiotic mismatch repair involved in reciprocal meiotic recombination,biological_process
64363,GO:0010778,The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.,meiotic DNA repair synthesis involved in reciprocal meiotic recombination,biological_process
64364,GO:0010780,The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.,meiotic DNA double-strand break formation involved in reciprocal meiotic recombination,biological_process
64365,GO:0010782,The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.,"proboscis morphogenesis, labial disc-derived",biological_process
64366,GO:0010783,The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.,"proboscis morphogenesis, eye-antennal disc-derived",biological_process
64367,GO:0010784,The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.,"proboscis morphogenesis, clypeo-labral disc-derived",biological_process
64368,GO:0010786,"The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.","clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting",biological_process
64369,GO:0010787,"The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.","COPI coating of Golgi vesicle, inter-Golgi cisterna",biological_process
64370,GO:0010788,"The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.","COPI coating of Golgi vesicle, cis-Golgi to rough ER",biological_process
64371,GO:0010789,The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.,meiosis I sister chromatid cohesion,biological_process
64372,GO:0010790,The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.,meiosis II sister chromatid cohesion,biological_process
64373,GO:0010791,The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.,DNA double-strand break processing involved in repair via synthesis-dependent strand annealing,biological_process
64374,GO:0010792,The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.,DNA double-strand break processing involved in repair via single-strand annealing,biological_process
64375,GO:0010793,"Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.",regulation of mRNA export from nucleus,biological_process
64376,GO:0010794,"Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.",regulation of dolichyl monophosphate biosynthetic process,biological_process
64377,GO:0010795,"Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.",regulation of ubiquinone biosynthetic process,biological_process
64378,GO:0010799,"Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.",regulation of peptidyl-threonine phosphorylation,biological_process
64379,GO:0010800,"Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.",positive regulation of peptidyl-threonine phosphorylation,biological_process
64380,GO:0010801,"Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.",negative regulation of peptidyl-threonine phosphorylation,biological_process
64381,GO:0010803,Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.,regulation of tumor necrosis factor-mediated signaling pathway,biological_process
64382,GO:0010804,Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.,negative regulation of tumor necrosis factor-mediated signaling pathway,biological_process
64383,GO:0010807,"Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.",regulation of synaptic vesicle priming,biological_process
64384,GO:0010808,"Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.",positive regulation of synaptic vesicle priming,biological_process
64385,GO:0010809,"Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.",negative regulation of synaptic vesicle priming,biological_process
64386,GO:0010810,"Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.",regulation of cell-substrate adhesion,biological_process
64387,GO:0010811,"Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.",positive regulation of cell-substrate adhesion,biological_process
64388,GO:0010812,"Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.",negative regulation of cell-substrate adhesion,biological_process
64389,GO:0010813,The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.,neuropeptide catabolic process,biological_process
64390,GO:0010814,The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.,substance P catabolic process,biological_process
64391,GO:0010815,The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.,bradykinin catabolic process,biological_process
64392,GO:0010816,The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.,calcitonin catabolic process,biological_process
64393,GO:0010817,"Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.",regulation of hormone levels,biological_process
64394,GO:0010818,The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.,T cell chemotaxis,biological_process
64395,GO:0010819,"Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.",regulation of T cell chemotaxis,biological_process
64396,GO:0010820,"Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.",positive regulation of T cell chemotaxis,biological_process
64397,GO:0010821,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.",regulation of mitochondrion organization,biological_process
64398,GO:0010824,"Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.",regulation of centrosome duplication,biological_process
64399,GO:0010825,"Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.",positive regulation of centrosome duplication,biological_process
64400,GO:0010826,"Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.",negative regulation of centrosome duplication,biological_process
64401,GO:0010827,"Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of D-glucose transmembrane transport,biological_process
64402,GO:0010828,"Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of D-glucose transmembrane transport,biological_process
64403,GO:0010829,"Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of D-glucose transmembrane transport,biological_process
64404,GO:0010830,"Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",regulation of myotube differentiation,biological_process
64405,GO:0010831,"Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",positive regulation of myotube differentiation,biological_process
64406,GO:0010832,"Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",negative regulation of myotube differentiation,biological_process
64407,GO:0010833,Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.,telomere maintenance via telomere lengthening,biological_process
64408,GO:0010835,"Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.",regulation of protein ADP-ribosylation,biological_process
64409,GO:0010836,"Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.",negative regulation of protein ADP-ribosylation,biological_process
64410,GO:0010837,"Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.",regulation of keratinocyte proliferation,biological_process
64411,GO:0010838,"Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.",positive regulation of keratinocyte proliferation,biological_process
64412,GO:0010839,"Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.",negative regulation of keratinocyte proliferation,biological_process
64413,GO:0010840,"Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.","regulation of circadian sleep/wake cycle, wakefulness",biological_process
64414,GO:0010841,"Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.","positive regulation of circadian sleep/wake cycle, wakefulness",biological_process
64415,GO:0010842,"The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and ...",retina layer formation,biological_process
64416,GO:0010844,Binding to a genomic region which promotes recombination.,recombination hotspot binding,molecular_function
64417,GO:0010845,"Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.",positive regulation of reciprocal meiotic recombination,biological_process
64418,GO:0010846,Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.,activation of reciprocal meiotic recombination,biological_process
64419,GO:0010850,"A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.",regulation of blood pressure by chemoreceptor signaling pathway,biological_process
64420,GO:0010851,Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.,cyclase regulator activity,molecular_function
64421,GO:0010852,Binds to and decreases the activity of an enzyme that catalyzes a ring closure reaction.,cyclase inhibitor activity,molecular_function
64422,GO:0010853,Binds to and increases the activity of an enzyme that catalyzes a ring closure reaction.,cyclase activator activity,molecular_function
64423,GO:0010854,Binds to and modulates the activity of adenylate cyclase.,adenylate cyclase regulator activity,molecular_function
64424,GO:0010855,Binds to and decreases the activity of adenylate cyclase.,adenylate cyclase inhibitor activity,molecular_function
64425,GO:0010856,Binds to and increases the activity of adenylate cyclase.,adenylate cyclase activator activity,molecular_function
64426,GO:0010858,"Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.",calcium-dependent protein kinase regulator activity,molecular_function
64427,GO:0010859,"Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.",calcium-dependent cysteine-type endopeptidase inhibitor activity,molecular_function
64428,GO:0010865,"The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.",stipule development,biological_process
64429,GO:0010866,"Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.",regulation of triglyceride biosynthetic process,biological_process
64430,GO:0010867,"Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.",positive regulation of triglyceride biosynthetic process,biological_process
64431,GO:0010868,"Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.",negative regulation of triglyceride biosynthetic process,biological_process
64432,GO:0010874,"Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.",regulation of cholesterol efflux,biological_process
64433,GO:0010875,"Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.",positive regulation of cholesterol efflux,biological_process
64434,GO:0010876,"Any process in which a lipid is transported to, or maintained in, a specific location.",lipid localization,biological_process
64435,GO:0010877,The directed movement of lipids into cells that is part of their accumulation and maintenance.,lipid transport involved in lipid storage,biological_process
64436,GO:0010878,"The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",cholesterol storage,biological_process
64437,GO:0010879,The directed movement of cholesterol into cells that is part of their accumulation and maintenance.,cholesterol transport involved in cholesterol storage,biological_process
64438,GO:0010880,"Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.",regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,biological_process
64439,GO:0010881,"Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.",regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion,biological_process
64440,GO:0010882,"Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.",regulation of cardiac muscle contraction by calcium ion signaling,biological_process
64441,GO:0010883,"Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.",regulation of lipid storage,biological_process
64442,GO:0010884,"Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.",positive regulation of lipid storage,biological_process
64443,GO:0010885,"Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",regulation of cholesterol storage,biological_process
64444,GO:0010886,"Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",positive regulation of cholesterol storage,biological_process
64445,GO:0010887,"Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",negative regulation of cholesterol storage,biological_process
64446,GO:0010888,"Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.",negative regulation of lipid storage,biological_process
64447,GO:0010889,"Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.",regulation of triglyceride storage,biological_process
64448,GO:0010890,"Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.",positive regulation of triglyceride storage,biological_process
64449,GO:0010891,"Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.",negative regulation of triglyceride storage,biological_process
64450,GO:0010892,"Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.",positive regulation of mitochondrial translation in response to stress,biological_process
64451,GO:0010893,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.",positive regulation of steroid biosynthetic process,biological_process
64452,GO:0010894,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.",negative regulation of steroid biosynthetic process,biological_process
64453,GO:0010895,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.",negative regulation of ergosterol biosynthetic process,biological_process
64454,GO:0010896,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.",regulation of triglyceride catabolic process,biological_process
64455,GO:0010897,"Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.",negative regulation of triglyceride catabolic process,biological_process
64456,GO:0010898,"Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.",positive regulation of triglyceride catabolic process,biological_process
64457,GO:0010899,"Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.",regulation of phosphatidylcholine catabolic process,biological_process
64458,GO:0010900,"Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.",negative regulation of phosphatidylcholine catabolic process,biological_process
64459,GO:0010901,"Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.",regulation of very-low-density lipoprotein particle remodeling,biological_process
64460,GO:0010902,"Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.",positive regulation of very-low-density lipoprotein particle remodeling,biological_process
64461,GO:0010903,"Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.",negative regulation of very-low-density lipoprotein particle remodeling,biological_process
64462,GO:0010906,"Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.",regulation of glucose metabolic process,biological_process
64463,GO:0010907,"Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.",positive regulation of glucose metabolic process,biological_process
64464,GO:0010908,"Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, which consists of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid.",regulation of heparan sulfate proteoglycan biosynthetic process,biological_process
64465,GO:0010909,"Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, which consists of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid.",positive regulation of heparan sulfate proteoglycan biosynthetic process,biological_process
64466,GO:0010913,"Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.",regulation of sterigmatocystin biosynthetic process,biological_process
64467,GO:0010914,"Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.",positive regulation of sterigmatocystin biosynthetic process,biological_process
64468,GO:0010915,"Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",regulation of very-low-density lipoprotein particle clearance,biological_process
64469,GO:0010916,"Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",negative regulation of very-low-density lipoprotein particle clearance,biological_process
64470,GO:0010917,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",negative regulation of mitochondrial membrane potential,biological_process
64471,GO:0010918,"Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",positive regulation of mitochondrial membrane potential,biological_process
64472,GO:0010919,"Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",regulation of inositol phosphate biosynthetic process,biological_process
64473,GO:0010920,"Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",negative regulation of inositol phosphate biosynthetic process,biological_process
64474,GO:0010921,"Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing phosphate.",regulation of phosphatase activity,biological_process
64475,GO:0010922,"Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.",positive regulation of phosphatase activity,biological_process
64476,GO:0010923,"Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.",negative regulation of phosphatase activity,biological_process
64477,GO:0010927,The cellular component assembly that is part of the initial shaping of the component during its developmental progression.,cellular component assembly involved in morphogenesis,biological_process
64478,GO:0010928,"Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.",regulation of auxin mediated signaling pathway,biological_process
64479,GO:0010929,"Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.",positive regulation of auxin mediated signaling pathway,biological_process
64480,GO:0010930,"Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.",negative regulation of auxin mediated signaling pathway,biological_process
64481,GO:0010931,A process involving any mechanism for tolerance induction in macrophages.,macrophage tolerance induction,biological_process
64482,GO:0010932,"Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.",regulation of macrophage tolerance induction,biological_process
64483,GO:0010933,"Any process that increases the frequency, rate, or extent of B cell tolerance induction.",positive regulation of macrophage tolerance induction,biological_process
64484,GO:0010934,"The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",macrophage cytokine production,biological_process
64485,GO:0010935,"Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",regulation of macrophage cytokine production,biological_process
64486,GO:0010936,"Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",negative regulation of macrophage cytokine production,biological_process
64487,GO:0010937,"Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.",regulation of cytoplasmic microtubule depolymerization,biological_process
64488,GO:0010938,The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.,cytoplasmic microtubule depolymerization,biological_process
64489,GO:0010943,Catalysis of the reaction: NADPH + H2O = NMNH + ADP.,NADPH pyrophosphatase activity,molecular_function
64490,GO:0010945,"Catalysis of the reaction: an acyl-coenzyme A or its derivatives + H2O = adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H+. This reaction can also use coenzyme A as a substrate.",coenzyme A diphosphatase activity,molecular_function
64491,GO:0010946,"Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.",regulation of meiotic joint molecule formation,biological_process
64492,GO:0010947,"Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.",negative regulation of meiotic joint molecule formation,biological_process
64493,GO:0010948,"Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.",negative regulation of cell cycle process,biological_process
64494,GO:0010949,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.",negative regulation of intestinal phytosterol absorption,biological_process
64495,GO:0010950,"Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.",positive regulation of endopeptidase activity,biological_process
64496,GO:0010951,"Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.",negative regulation of endopeptidase activity,biological_process
64497,GO:0010952,"Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.",positive regulation of peptidase activity,biological_process
64498,GO:0010954,"Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.",positive regulation of protein processing,biological_process
64499,GO:0010955,"Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.",negative regulation of protein processing,biological_process
64500,GO:0010957,"Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",negative regulation of vitamin D biosynthetic process,biological_process
64501,GO:0010958,"Any process that modulates the frequency, rate or extent of amino acid import into a cell.",regulation of amino acid import across plasma membrane,biological_process
64502,GO:0010959,"Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of metal ion transport,biological_process
64503,GO:0010960,Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.,magnesium ion homeostasis,biological_process
64504,GO:0010961,A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell.,intracellular magnesium ion homeostasis,biological_process
64505,GO:0010962,"Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.",regulation of glucan biosynthetic process,biological_process
64506,GO:0010964,"Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.",regulation of regulatory ncRNA-mediated heterochromatin formation,biological_process
64507,GO:0010965,"Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.",regulation of mitotic sister chromatid separation,biological_process
64508,GO:0010966,"Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of phosphate transport,biological_process
64509,GO:0010967,"Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.",regulation of polyamine biosynthetic process,biological_process
64510,GO:0010968,"Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.",regulation of microtubule nucleation,biological_process
64511,GO:0010970,"The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.",transport along microtubule,biological_process
64512,GO:0010971,Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.,positive regulation of G2/M transition of mitotic cell cycle,biological_process
64513,GO:0010972,Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.,negative regulation of G2/M transition of mitotic cell cycle,biological_process
64514,GO:0010973,"Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",positive regulation of division septum assembly,biological_process
64515,GO:0010974,"Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",negative regulation of division septum assembly,biological_process
64516,GO:0010975,"Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).",regulation of neuron projection development,biological_process
64517,GO:0010976,"Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).",positive regulation of neuron projection development,biological_process
64518,GO:0010977,"Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).",negative regulation of neuron projection development,biological_process
64519,GO:0010981,"Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.",regulation of cell wall macromolecule metabolic process,biological_process
64520,GO:0010982,"Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",regulation of high-density lipoprotein particle clearance,biological_process
64521,GO:0010983,"Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",positive regulation of high-density lipoprotein particle clearance,biological_process
64522,GO:0010984,"Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",regulation of lipoprotein particle clearance,biological_process
64523,GO:0010985,"Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",negative regulation of lipoprotein particle clearance,biological_process
64524,GO:0010986,"Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",positive regulation of lipoprotein particle clearance,biological_process
64525,GO:0010987,"Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",negative regulation of high-density lipoprotein particle clearance,biological_process
64526,GO:0010988,"Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",regulation of low-density lipoprotein particle clearance,biological_process
64527,GO:0010989,"Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.",negative regulation of low-density lipoprotein particle clearance,biological_process
64528,GO:0010992,Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.,ubiquitin recycling,biological_process
64529,GO:0010994,"The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.",free ubiquitin chain polymerization,biological_process
64530,GO:0010995,"The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.",free ubiquitin chain depolymerization,biological_process
64531,GO:0010996,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.",response to auditory stimulus,biological_process
64532,GO:0010997,"Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.",anaphase-promoting complex binding,molecular_function
64533,GO:0010998,"Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.",regulation of translational initiation by eIF2 alpha phosphorylation,biological_process
64534,GO:0010999,"Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.",regulation of eIF2 alpha phosphorylation by heme,biological_process
64535,GO:0011000,A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.,replication fork arrest at mating type locus,biological_process
64536,GO:0012501,A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.,programmed cell death,biological_process
64537,GO:0012502,A process which directly activates any of the steps required for programmed cell death.,induction of programmed cell death,biological_process
64538,GO:0012505,"A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.",endomembrane system,cellular_component
64539,GO:0012506,The lipid bilayer surrounding any membrane-bounded vesicle in the cell.,vesicle membrane,cellular_component
64540,GO:0012507,The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.,ER to Golgi transport vesicle membrane,cellular_component
64541,GO:0012508,The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.,Golgi to ER transport vesicle membrane,cellular_component
64542,GO:0012509,The lipid bilayer surrounding a vesicle transporting substances within the Golgi.,inter-Golgi transport vesicle membrane,cellular_component
64543,GO:0012510,The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.,trans-Golgi network transport vesicle membrane,cellular_component
64544,GO:0012511,"A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.",monolayer-surrounded lipid storage body,cellular_component
64545,GO:0014000,The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum.,morula development,biological_process
64546,GO:0014001,"The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.",sclerenchyma cell differentiation,biological_process
64547,GO:0014002,"The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.",astrocyte development,biological_process
64548,GO:0014003,"The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.",oligodendrocyte development,biological_process
64549,GO:0014004,The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.,microglia differentiation,biological_process
64550,GO:0014005,"The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",microglia development,biological_process
64551,GO:0014006,"Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.",regulation of microglia differentiation,biological_process
64552,GO:0014007,"Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.",negative regulation of microglia differentiation,biological_process
64553,GO:0014008,"Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.",positive regulation of microglia differentiation,biological_process
64554,GO:0014009,"The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.",glial cell proliferation,biological_process
64555,GO:0014010,"The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.",Schwann cell proliferation,biological_process
64556,GO:0014012,The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.,peripheral nervous system axon regeneration,biological_process
64557,GO:0014013,"Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.",regulation of gliogenesis,biological_process
64558,GO:0014014,"Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.",negative regulation of gliogenesis,biological_process
64559,GO:0014015,"Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.",positive regulation of gliogenesis,biological_process
64560,GO:0014016,The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.,neuroblast differentiation,biological_process
64561,GO:0014017,The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.,neuroblast fate commitment,biological_process
64562,GO:0014018,"The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",neuroblast fate specification,biological_process
64563,GO:0014019,"The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.",neuroblast development,biological_process
64564,GO:0014020,"The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.",primary neural tube formation,biological_process
64565,GO:0014021,The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.,secondary neural tube formation,biological_process
64566,GO:0014022,The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.,neural plate elongation,biological_process
64567,GO:0014023,The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.,neural rod formation,biological_process
64568,GO:0014025,The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.,neural keel formation,biological_process
64569,GO:0014028,"The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.",notochord formation,biological_process
64570,GO:0014029,The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.,neural crest formation,biological_process
64571,GO:0014030,The process in which a cell becomes committed to become a mesenchymal cell.,mesenchymal cell fate commitment,biological_process
64572,GO:0014031,"The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",mesenchymal cell development,biological_process
64573,GO:0014032,"The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",neural crest cell development,biological_process
64574,GO:0014033,The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.,neural crest cell differentiation,biological_process
64575,GO:0014034,The process in which a cell becomes committed to become a neural crest cell.,neural crest cell fate commitment,biological_process
64576,GO:0014035,"The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.",neural crest cell fate determination,biological_process
64577,GO:0014036,"The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",neural crest cell fate specification,biological_process
64578,GO:0014037,"The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.",Schwann cell differentiation,biological_process
64579,GO:0014038,"Any process that modulates the frequency, rate or extent of Schwann cell differentiation.",regulation of Schwann cell differentiation,biological_process
64580,GO:0014039,"Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.",negative regulation of Schwann cell differentiation,biological_process
64581,GO:0014040,"Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.",positive regulation of Schwann cell differentiation,biological_process
64582,GO:0014041,"Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.",regulation of neuron maturation,biological_process
64583,GO:0014042,"Any process that activates or increases the frequency, rate or extent of neuron maturation.",positive regulation of neuron maturation,biological_process
64584,GO:0014043,"Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.",negative regulation of neuron maturation,biological_process
64585,GO:0014044,"The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.",Schwann cell development,biological_process
64586,GO:0014045,Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.,establishment of endothelial blood-brain barrier,biological_process
64587,GO:0014046,The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.,dopamine secretion,biological_process
64588,GO:0014047,The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.,glutamate secretion,biological_process
64589,GO:0014048,"Any process that modulates the frequency, rate or extent of the controlled release of glutamate.",regulation of glutamate secretion,biological_process
64590,GO:0014049,"Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.",positive regulation of glutamate secretion,biological_process
64591,GO:0014050,"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.",negative regulation of glutamate secretion,biological_process
64592,GO:0014051,The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.,gamma-aminobutyric acid secretion,biological_process
64593,GO:0014052,"Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.",regulation of gamma-aminobutyric acid secretion,biological_process
64594,GO:0014053,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.",negative regulation of gamma-aminobutyric acid secretion,biological_process
64595,GO:0014054,"Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.",positive regulation of gamma-aminobutyric acid secretion,biological_process
64596,GO:0014055,The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).,"acetylcholine secretion, neurotransmission",biological_process
64597,GO:0014056,"Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.","regulation of acetylcholine secretion, neurotransmission",biological_process
64598,GO:0014057,"Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.","positive regulation of acetylcholine secretion, neurotransmission",biological_process
64599,GO:0014058,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.","negative regulation of acetylcholine secretion, neurotransmission",biological_process
64600,GO:0014059,"Any process that modulates the frequency, rate or extent of the regulated release of dopamine.",regulation of dopamine secretion,biological_process
64601,GO:0014060,"Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.",regulation of epinephrine secretion,biological_process
64602,GO:0014061,"Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.",regulation of norepinephrine secretion,biological_process
64603,GO:0014062,"Any process that modulates the frequency, rate or extent of the regulated release of serotonin.",regulation of serotonin secretion,biological_process
64604,GO:0014063,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.",negative regulation of serotonin secretion,biological_process
64605,GO:0014064,"Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.",positive regulation of serotonin secretion,biological_process
64606,GO:0014069,"An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.",postsynaptic density,cellular_component
64607,GO:0014071,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.",response to cycloalkane,biological_process
64608,GO:0014072,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.",response to isoquinoline alkaloid,biological_process
64609,GO:0014073,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.",response to tropane,biological_process
64610,GO:0014074,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.",response to purine-containing compound,biological_process
64611,GO:0014075,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.",response to amine,biological_process
64612,GO:0014076,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.",response to fluoxetine,biological_process
64613,GO:0014701,"The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.",junctional sarcoplasmic reticulum membrane,cellular_component
64614,GO:0014702,The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.,free sarcoplasmic reticulum membrane,cellular_component
64615,GO:0014703,"A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.",oscillatory muscle contraction,biological_process
64616,GO:0014704,A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.,intercalated disc,cellular_component
64617,GO:0014705,A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.,C zone,cellular_component
64618,GO:0014706,"The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.",striated muscle tissue development,biological_process
64619,GO:0014707,"The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.",branchiomeric skeletal muscle development,biological_process
64620,GO:0014708,"Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.",regulation of somitomeric trunk muscle development,biological_process
64621,GO:0014709,"Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.",positive regulation of somitomeric trunk muscle development,biological_process
64622,GO:0014710,"Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.",negative regulation of somitomeric trunk muscle development,biological_process
64623,GO:0014711,"Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.",regulation of branchiomeric skeletal muscle development,biological_process
64624,GO:0014712,"Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.",positive regulation of branchiomeric skeletal muscle development,biological_process
64625,GO:0014713,"Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.",negative regulation of branchiomeric skeletal muscle development,biological_process
64626,GO:0014714,"The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fate commitment in head,biological_process
64627,GO:0014715,"The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fate commitment in trunk,biological_process
64628,GO:0014717,"Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.",regulation of satellite cell activation involved in skeletal muscle regeneration,biological_process
64629,GO:0014718,"Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.",positive regulation of satellite cell activation involved in skeletal muscle regeneration,biological_process
64630,GO:0014719,"The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.",skeletal muscle satellite cell activation,biological_process
64631,GO:0014720,"A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.",tonic skeletal muscle contraction,biological_process
64632,GO:0014721,"A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.",twitch skeletal muscle contraction,biological_process
64633,GO:0014722,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.",regulation of skeletal muscle contraction by calcium ion signaling,biological_process
64634,GO:0014723,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.",regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril,biological_process
64635,GO:0014724,"Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.",regulation of twitch skeletal muscle contraction,biological_process
64636,GO:0014725,"Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.",regulation of extraocular skeletal muscle development,biological_process
64637,GO:0014726,"Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature mus...",negative regulation of extraocular skeletal muscle development,biological_process
64638,GO:0014727,"Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the matu...",positive regulation of extraocular skeletal muscle development,biological_process
64639,GO:0014728,"Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.",regulation of the force of skeletal muscle contraction,biological_process
64640,GO:0014729,Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.,regulation of the velocity of shortening of skeletal muscle modulating contraction,biological_process
64641,GO:0014730,The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.,skeletal muscle regeneration at neuromuscular junction,biological_process
64642,GO:0014731,"The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.",spectrin-associated cytoskeleton,cellular_component
64643,GO:0014732,"A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.",skeletal muscle atrophy,biological_process
64644,GO:0014733,"Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.",regulation of skeletal muscle adaptation,biological_process
64645,GO:0014734,The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.,skeletal muscle hypertrophy,biological_process
64646,GO:0014735,"Any process that modulates the frequency, rate or extent of muscle atrophy.",regulation of muscle atrophy,biological_process
64647,GO:0014736,"Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.",negative regulation of muscle atrophy,biological_process
64648,GO:0014737,"Any process that activates or increases the frequency, rate or extent of muscle atrophy.",positive regulation of muscle atrophy,biological_process
64649,GO:0014738,"Any process that modulates the frequency, rate or extent of muscle hyperplasia.",regulation of muscle hyperplasia,biological_process
64650,GO:0014739,"Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.",positive regulation of muscle hyperplasia,biological_process
64651,GO:0014740,"Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.",negative regulation of muscle hyperplasia,biological_process
64652,GO:0014741,"Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.",negative regulation of muscle hypertrophy,biological_process
64653,GO:0014742,"Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.",positive regulation of muscle hypertrophy,biological_process
64654,GO:0014743,"Any process that modulates the frequency, rate or extent of muscle hypertrophy.",regulation of muscle hypertrophy,biological_process
64655,GO:0014744,"Any process that activates or increases the frequency, rate or extent of muscle adaptation.",positive regulation of muscle adaptation,biological_process
64656,GO:0014745,"Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.",negative regulation of muscle adaptation,biological_process
64657,GO:0014746,"Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.",regulation of tonic skeletal muscle contraction,biological_process
64658,GO:0014747,"Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.",positive regulation of tonic skeletal muscle contraction,biological_process
64659,GO:0014748,"Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.",negative regulation of tonic skeletal muscle contraction,biological_process
64660,GO:0014801,The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.,longitudinal sarcoplasmic reticulum,cellular_component
64661,GO:0014802,The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.,terminal cisterna,cellular_component
64662,GO:0014803,The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.,longitudinal sarcoplasmic reticulum lumen,cellular_component
64663,GO:0014804,The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.,terminal cisterna lumen,cellular_component
64664,GO:0014805,"Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.",smooth muscle adaptation,biological_process
64665,GO:0014806,"A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.",smooth muscle hyperplasia,biological_process
64666,GO:0014807,"Any process that modulates the frequency, rate or extent of somitogenesis.",regulation of somitogenesis,biological_process
64667,GO:0014808,The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.,release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,biological_process
64668,GO:0014809,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.",regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion,biological_process
64669,GO:0014810,"Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.",positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion,biological_process
64670,GO:0014811,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.",negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion,biological_process
64671,GO:0014812,"The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.",muscle cell migration,biological_process
64672,GO:0014813,The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.,skeletal muscle satellite cell commitment,biological_process
64673,GO:0014814,The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.,axon regeneration at neuromuscular junction,biological_process
64674,GO:0014816,The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.,skeletal muscle satellite cell differentiation,biological_process
64675,GO:0014817,"The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",skeletal muscle satellite cell fate specification,biological_process
64676,GO:0014818,"The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.",skeletal muscle satellite cell fate determination,biological_process
64677,GO:0014819,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction.",regulation of skeletal muscle contraction,biological_process
64678,GO:0014820,"A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.",tonic smooth muscle contraction,biological_process
64679,GO:0014821,"A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.",phasic smooth muscle contraction,biological_process
64680,GO:0014822,The series of events by which an injury stimulus is received and converted into a molecular signal.,detection of wounding,biological_process
64681,GO:0014823,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.",response to activity,biological_process
64682,GO:0014824,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.",artery smooth muscle contraction,biological_process
64683,GO:0014825,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.",stomach fundus smooth muscle contraction,biological_process
64684,GO:0014826,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.",vein smooth muscle contraction,biological_process
64685,GO:0014827,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.",intestine smooth muscle contraction,biological_process
64686,GO:0014828,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.",distal stomach smooth muscle contraction,biological_process
64687,GO:0014829,"A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.",vascular associated smooth muscle contraction,biological_process
64688,GO:0014830,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.",arteriole smooth muscle contraction,biological_process
64689,GO:0014831,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (l...",gastro-intestinal system smooth muscle contraction,biological_process
64690,GO:0014832,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.",urinary bladder smooth muscle contraction,biological_process
64691,GO:0014833,"The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.",skeletal muscle satellite stem cell asymmetric division,biological_process
64692,GO:0014834,Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back ...,skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration,biological_process
64693,GO:0014835,"The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast differentiation involved in skeletal muscle regeneration,biological_process
64694,GO:0014839,"The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast migration involved in skeletal muscle regeneration,biological_process
64695,GO:0014841,"The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.",skeletal muscle satellite cell proliferation,biological_process
64696,GO:0014842,"Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.",regulation of skeletal muscle satellite cell proliferation,biological_process
64697,GO:0014843,"Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.",growth factor dependent regulation of skeletal muscle satellite cell proliferation,biological_process
64698,GO:0014844,"The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast proliferation involved in skeletal muscle regeneration,biological_process
64699,GO:0014845,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.",stomach body smooth muscle contraction,biological_process
64700,GO:0014846,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.",esophagus smooth muscle contraction,biological_process
64701,GO:0014847,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within ...",proximal stomach smooth muscle contraction,biological_process
64702,GO:0014848,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.",urinary tract smooth muscle contraction,biological_process
64703,GO:0014849,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.",ureter smooth muscle contraction,biological_process
64704,GO:0014850,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.",response to muscle activity,biological_process
64705,GO:0014852,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.",regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction,biological_process
64706,GO:0014853,"Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.",regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction,biological_process
64707,GO:0014854,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.",response to inactivity,biological_process
64708,GO:0014855,"The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.",striated muscle cell proliferation,biological_process
64709,GO:0014856,"The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.",skeletal muscle cell proliferation,biological_process
64710,GO:0014857,"Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.",regulation of skeletal muscle cell proliferation,biological_process
64711,GO:0014858,"Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.",positive regulation of skeletal muscle cell proliferation,biological_process
64712,GO:0014859,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.",negative regulation of skeletal muscle cell proliferation,biological_process
64713,GO:0014860,"The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glyci...",neurotransmitter secretion involved in regulation of skeletal muscle contraction,biological_process
64714,GO:0014861,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.",regulation of skeletal muscle contraction via regulation of action potential,biological_process
64715,GO:0014862,"Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.",regulation of skeletal muscle contraction by chemo-mechanical energy conversion,biological_process
64716,GO:0014863,The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.,detection of inactivity,biological_process
64717,GO:0014864,The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.,detection of muscle activity,biological_process
64718,GO:0014865,The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.,detection of activity,biological_process
64719,GO:0014866,"The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.",skeletal myofibril assembly,biological_process
64720,GO:0014869,The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.,detection of muscle inactivity,biological_process
64721,GO:0014870,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.",response to muscle inactivity,biological_process
64722,GO:0014872,"The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast division,biological_process
64723,GO:0014873,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.",response to muscle activity involved in regulation of muscle adaptation,biological_process
64724,GO:0014876,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.",response to injury involved in regulation of muscle adaptation,biological_process
64725,GO:0014878,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.",response to electrical stimulus involved in regulation of muscle adaptation,biological_process
64726,GO:0014881,"Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.",regulation of myofibril size,biological_process
64727,GO:0014882,"Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.",regulation of myofibril number,biological_process
64728,GO:0014883,"The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.",transition between fast and slow fiber,biological_process
64729,GO:0014886,"The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.",transition between slow and fast fiber,biological_process
64730,GO:0014887,"The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.",cardiac muscle adaptation,biological_process
64731,GO:0014888,"Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.",striated muscle adaptation,biological_process
64732,GO:0014889,"A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.",muscle atrophy,biological_process
64733,GO:0014890,"A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.",smooth muscle atrophy,biological_process
64734,GO:0014891,"A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.",striated muscle atrophy,biological_process
64735,GO:0014894,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.",response to denervation involved in regulation of muscle adaptation,biological_process
64736,GO:0014895,"The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.",smooth muscle hypertrophy,biological_process
64737,GO:0014896,The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregna...,muscle hypertrophy,biological_process
64738,GO:0014897,"The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.",striated muscle hypertrophy,biological_process
64739,GO:0014898,"The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.",cardiac muscle hypertrophy in response to stress,biological_process
64740,GO:0014899,"A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.",cardiac muscle atrophy,biological_process
64741,GO:0014900,"A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.",muscle hyperplasia,biological_process
64742,GO:0014901,"The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.",satellite cell activation involved in skeletal muscle regeneration,biological_process
64743,GO:0014902,"The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",myotube differentiation,biological_process
64744,GO:0014904,"The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",myotube cell development,biological_process
64745,GO:0014905,"A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fusion involved in skeletal muscle regeneration,biological_process
64746,GO:0014906,"The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.",myotube cell development involved in skeletal muscle regeneration,biological_process
64747,GO:0014908,"The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, diffe...",myotube differentiation involved in skeletal muscle regeneration,biological_process
64748,GO:0014909,"The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.",smooth muscle cell migration,biological_process
64749,GO:0014910,"Any process that modulates the frequency, rate or extent of smooth muscle cell migration.",regulation of smooth muscle cell migration,biological_process
64750,GO:0014911,"Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.",positive regulation of smooth muscle cell migration,biological_process
64751,GO:0014912,"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.",negative regulation of smooth muscle cell migration,biological_process
64752,GO:0014916,The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.,regulation of lung blood pressure,biological_process
64753,GO:0015012,"The chemical reactions and pathways resulting in the formation of heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-gluc...",heparan sulfate proteoglycan biosynthetic process,biological_process
64754,GO:0015016,"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n) = adenosine 3',5'-bisphosphate + 2 H+ + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n).",heparan sulfate N-sulfotransferase activity,molecular_function
64755,GO:0015018,Catalysis of the reaction: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.,galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity,molecular_function
64756,GO:0015019,Catalysis of the reaction: alpha-D-glucosaminyl-[heparan sulfate](n) + acetyl-CoA = N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) + CoA + H+.,heparan-alpha-glucosaminide N-acetyltransferase activity,molecular_function
64757,GO:0015020,Catalysis of the reaction: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H+ + UDP.,glucuronosyltransferase activity,molecular_function
64758,GO:0015021,Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.,heparin-sulfate lyase activity,molecular_function
64759,GO:0015024,"Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.",glucuronate-2-sulfatase activity,molecular_function
64760,GO:0015026,"Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.",coreceptor activity,molecular_function
64761,GO:0015030,"A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particl...",Cajal body,cellular_component
64762,GO:0015031,"The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",protein transport,biological_process
64763,GO:0015035,Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.,protein-disulfide reductase activity,molecular_function
64764,GO:0015036,Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.,disulfide oxidoreductase activity,molecular_function
64765,GO:0015038,Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.,glutathione disulfide oxidoreductase activity,molecular_function
64766,GO:0015042,Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.,trypanothione-disulfide reductase (NADPH) activity,molecular_function
64767,GO:0015043,Catalysis of the reaction: 2 Fe(III)-[leghemoglobin] + NAD(P)H = 2 Fe(II)-[leghemoglobin] + NAD(P)+ + H+.,leghemoglobin reductase [NAD(P)H] activity,molecular_function
64768,GO:0015044,Catalysis of the reaction: 2 reduced [rubredoxin] + NAD+ + H+ = 2 oxidized [rubredoxin] + NADH.,rubredoxin-NAD+ reductase activity,molecular_function
64769,GO:0015045,Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.,rubredoxin-NAD(P)H reductase activity,molecular_function
64770,GO:0015046,Catalysis of the reaction: 2 reduced [rubredoxin] + NADP+ + H+ = 2 oxidized [rubredoxin] + NADPH.,rubredoxin-NADP+ reductase activity,molecular_function
64771,GO:0015047,Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.,NADPH-cytochrome-c2 reductase activity,molecular_function
64772,GO:0015049,Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.,methane monooxygenase [NAD(P)H] activity,molecular_function
64773,GO:0015050,A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.,methane monooxygenase complex,cellular_component
64774,GO:0015052,"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.",beta3-adrenergic receptor activity,molecular_function
64775,GO:0015054,Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.,gastrin receptor activity,molecular_function
64776,GO:0015055,Combining with secretin to initiate a change in cell activity.,secretin receptor activity,molecular_function
64777,GO:0015056,"Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.",corticotrophin-releasing factor receptor activity,molecular_function
64778,GO:0015057,"A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.",thrombin-activated receptor activity,molecular_function
64779,GO:0015066,"Binds to and stops, prevents or reduces the activity of alpha-amylase.",alpha-amylase inhibitor activity,molecular_function
64780,GO:0015067,Catalysis of the reversible transfer of an amidino group to an acceptor.,amidinotransferase activity,molecular_function
64781,GO:0015068,Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.,glycine amidinotransferase activity,molecular_function
64782,GO:0015069,Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.,scyllo-inosamine-4-phosphate amidinotransferase activity,molecular_function
64783,GO:0015074,"The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.",DNA integration,biological_process
64784,GO:0015075,Enables the transfer of an ion from one side of a membrane to the other.,monoatomic ion transmembrane transporter activity,molecular_function
64785,GO:0015078,Enables the transfer of a proton from one side of a membrane to the other.,proton transmembrane transporter activity,molecular_function
64786,GO:0015079,Enables the transfer of potassium ions (K+) from one side of a membrane to the other.,potassium ion transmembrane transporter activity,molecular_function
64787,GO:0015080,Enables the transfer of silver (Ag+) ions from one side of a membrane to the other.,silver ion transmembrane transporter activity,molecular_function
64788,GO:0015081,Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.,sodium ion transmembrane transporter activity,molecular_function
64789,GO:0015083,Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.,aluminum ion transmembrane transporter activity,molecular_function
64790,GO:0015085,Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.,calcium ion transmembrane transporter activity,molecular_function
64791,GO:0015086,Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.,cadmium ion transmembrane transporter activity,molecular_function
64792,GO:0015087,Enables the transfer of cobalt (Co2+) ions from one side of a membrane to the other.,cobalt ion transmembrane transporter activity,molecular_function
64793,GO:0015089,Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity copper ion transmembrane transporter activity,molecular_function
64794,GO:0015090,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity ferric iron ion transmembrane transporter activity,molecular_function
64795,GO:0015091,Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.,ferric iron transmembrane transporter activity,molecular_function
64796,GO:0015092,Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity ferric iron transmembrane transporter activity,molecular_function
64797,GO:0015093,Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.,ferrous iron transmembrane transporter activity,molecular_function
64798,GO:0015094,Enables the transfer of lead (Pb) ions from one side of a membrane to the other.,lead ion transmembrane transporter activity,molecular_function
64799,GO:0015095,Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.,magnesium ion transmembrane transporter activity,molecular_function
64800,GO:0015097,Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other.,mercury ion transmembrane transporter activity,molecular_function
64801,GO:0015098,Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.,molybdate ion transmembrane transporter activity,molecular_function
64802,GO:0015099,Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.,nickel cation transmembrane transporter activity,molecular_function
64803,GO:0015100,Enables the transfer of vanadium (V) ions from one side of a membrane to the other.,vanadium ion transmembrane transporter activity,molecular_function
64804,GO:0015104,Enables the transfer of antimonite from one side of a membrane to the other.,antimonite transmembrane transporter activity,molecular_function
64805,GO:0015105,Enables the transfer of arsenite from one side of a membrane to the other.,arsenite transmembrane transporter activity,molecular_function
64806,GO:0015106,"Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.",bicarbonate transmembrane transporter activity,molecular_function
64807,GO:0015107,"Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.",chlorate transmembrane transporter activity,molecular_function
64808,GO:0015108,Enables the transfer of chloride ions from one side of a membrane to the other.,chloride transmembrane transporter activity,molecular_function
64809,GO:0015109,"Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.",chromate transmembrane transporter activity,molecular_function
64810,GO:0015110,"Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.",cyanate transmembrane transporter activity,molecular_function
64811,GO:0015111,Enables the transfer of iodide ions from one side of a membrane to the other.,iodide transmembrane transporter activity,molecular_function
64812,GO:0015112,Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.,nitrate transmembrane transporter activity,molecular_function
64813,GO:0015113,Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.,nitrite transmembrane transporter activity,molecular_function
64814,GO:0015115,"Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.",silicate transmembrane transporter activity,molecular_function
64815,GO:0015116,"Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.",sulfate transmembrane transporter activity,molecular_function
64816,GO:0015117,"Enables the transfer of thiosulfate ions, HS2O3(1-), from one side of a membrane to the other.",thiosulfate transmembrane transporter activity,molecular_function
64817,GO:0015119,Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.,hexose phosphate transmembrane transporter activity,molecular_function
64818,GO:0015120,Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.,phosphoglycerate transmembrane transporter activity,molecular_function
64819,GO:0015121,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).,phosphoenolpyruvate:phosphate antiporter activity,molecular_function
64820,GO:0015123,Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.,acetate transmembrane transporter activity,molecular_function
64821,GO:0015124,"Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.",allantoate transmembrane transporter activity,molecular_function
64822,GO:0015125,"Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.",bile acid transmembrane transporter activity,molecular_function
64823,GO:0015126,"The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.",canalicular bile acid transmembrane transporter activity,molecular_function
64824,GO:0015127,"Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.",bilirubin transmembrane transporter activity,molecular_function
64825,GO:0015128,Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.,gluconate transmembrane transporter activity,molecular_function
64826,GO:0015129,"Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.",lactate transmembrane transporter activity,molecular_function
64827,GO:0015130,Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.,mevalonate transmembrane transporter activity,molecular_function
64828,GO:0015131,"Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other.",oxaloacetate transmembrane transporter activity,molecular_function
64829,GO:0015132,Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.,prostaglandin transmembrane transporter activity,molecular_function
64830,GO:0015133,"Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.",uronic acid transmembrane transporter activity,molecular_function
64831,GO:0015134,Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.,hexuronate transmembrane transporter activity,molecular_function
64832,GO:0015135,Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.,glucuronate transmembrane transporter activity,molecular_function
64833,GO:0015136,Enables the transfer of sialic acid from one side of a membrane to the other.,sialic acid transmembrane transporter activity,molecular_function
64834,GO:0015137,"Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboxylate, from one side of a membrane to the other.",citrate transmembrane transporter activity,molecular_function
64835,GO:0015138,Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.,fumarate transmembrane transporter activity,molecular_function
64836,GO:0015139,"Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.",alpha-ketoglutarate transmembrane transporter activity,molecular_function
64837,GO:0015140,"Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.",malate transmembrane transporter activity,molecular_function
64838,GO:0015141,"Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.",succinate transmembrane transporter activity,molecular_function
64839,GO:0015142,Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.,tricarboxylic acid transmembrane transporter activity,molecular_function
64840,GO:0015143,"Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.",urate transmembrane transporter activity,molecular_function
64841,GO:0015144,Enables the transfer of carbohydrate from one side of a membrane to the other.,carbohydrate transmembrane transporter activity,molecular_function
64842,GO:0015145,Enables the transfer of a monosaccharide from one side of a membrane to the other.,monosaccharide transmembrane transporter activity,molecular_function
64843,GO:0015146,Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.,pentose transmembrane transporter activity,molecular_function
64844,GO:0015147,"Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.",L-arabinose transmembrane transporter activity,molecular_function
64845,GO:0015148,Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.,D-xylose transmembrane transporter activity,molecular_function
64846,GO:0015149,"Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.",hexose transmembrane transporter activity,molecular_function
64847,GO:0015150,"Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.",fucose transmembrane transporter activity,molecular_function
64848,GO:0015151,"Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.",alpha-glucoside transmembrane transporter activity,molecular_function
64849,GO:0015152,Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.,glucose-6-phosphate transmembrane transporter activity,molecular_function
64850,GO:0015153,"Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.",rhamnose transmembrane transporter activity,molecular_function
64851,GO:0015154,Enables the transfer of disaccharide from one side of a membrane to the other.,disaccharide transmembrane transporter activity,molecular_function
64852,GO:0015155,"Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.",lactose transmembrane transporter activity,molecular_function
64853,GO:0015156,Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.,melibiose transmembrane transporter activity,molecular_function
64854,GO:0015157,Enables the transfer of oligosaccharide from one side of a membrane to the other.,oligosaccharide transmembrane transporter activity,molecular_function
64855,GO:0015158,"Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.",raffinose transmembrane transporter activity,molecular_function
64856,GO:0015159,Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.,polysaccharide transmembrane transporter activity,molecular_function
64857,GO:0015160,Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.,beta-glucan transmembrane transporter activity,molecular_function
64858,GO:0015161,"Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.",lipid III floppase activity,molecular_function
64859,GO:0015164,Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.,glucuronoside transmembrane transporter activity,molecular_function
64860,GO:0015165,Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.,pyrimidine nucleotide-sugar transmembrane transporter activity,molecular_function
64861,GO:0015166,Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.,polyol transmembrane transporter activity,molecular_function
64862,GO:0015167,Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.,arabitol transmembrane transporter activity,molecular_function
64863,GO:0015168,"Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.",glycerol transmembrane transporter activity,molecular_function
64864,GO:0015169,Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.,glycerol-3-phosphate transmembrane transporter activity,molecular_function
64865,GO:0015171,Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.,amino acid transmembrane transporter activity,molecular_function
64866,GO:0015172,Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.,acidic amino acid transmembrane transporter activity,molecular_function
64867,GO:0015173,Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.,aromatic amino acid transmembrane transporter activity,molecular_function
64868,GO:0015174,Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.,basic amino acid transmembrane transporter activity,molecular_function
64869,GO:0015175,Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.,neutral L-amino acid transmembrane transporter activity,molecular_function
64870,GO:0015179,Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.,L-amino acid transmembrane transporter activity,molecular_function
64871,GO:0015180,Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.,L-alanine transmembrane transporter activity,molecular_function
64872,GO:0015182,Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.,L-asparagine transmembrane transporter activity,molecular_function
64873,GO:0015183,Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.,L-aspartate transmembrane transporter activity,molecular_function
64874,GO:0015184,Enables the transfer of L-cystine from one side of a membrane to the other.,L-cystine transmembrane transporter activity,molecular_function
64875,GO:0015185,Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).,gamma-aminobutyric acid transmembrane transporter activity,molecular_function
64876,GO:0015186,Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.,L-glutamine transmembrane transporter activity,molecular_function
64877,GO:0015187,Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.,glycine transmembrane transporter activity,molecular_function
64878,GO:0015188,"Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.",L-isoleucine transmembrane transporter activity,molecular_function
64879,GO:0015189,"Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.",L-lysine transmembrane transporter activity,molecular_function
64880,GO:0015190,Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.,L-leucine transmembrane transporter activity,molecular_function
64881,GO:0015191,Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.,L-methionine transmembrane transporter activity,molecular_function
64882,GO:0015192,Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.,L-phenylalanine transmembrane transporter activity,molecular_function
64883,GO:0015193,Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.,L-proline transmembrane transporter activity,molecular_function
64884,GO:0015194,Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.,L-serine transmembrane transporter activity,molecular_function
64885,GO:0015195,"Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.",L-threonine transmembrane transporter activity,molecular_function
64886,GO:0015196,Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.,L-tryptophan transmembrane transporter activity,molecular_function
64887,GO:0015199,Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid.,amino-acid betaine transmembrane transporter activity,molecular_function
64888,GO:0015200,"Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.",methylammonium transmembrane transporter activity,molecular_function
64889,GO:0015203,"Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.",polyamine transmembrane transporter activity,molecular_function
64890,GO:0015204,Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.,urea transmembrane transporter activity,molecular_function
64891,GO:0015205,"Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.",nucleobase transmembrane transporter activity,molecular_function
64892,GO:0015207,"Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.",adenine transmembrane transporter activity,molecular_function
64893,GO:0015208,"Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.",guanine transmembrane transporter activity,molecular_function
64894,GO:0015209,"Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.",cytosine transmembrane transporter activity,molecular_function
64895,GO:0015210,"Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.",uracil transmembrane transporter activity,molecular_function
64896,GO:0015211,"Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.",purine nucleoside transmembrane transporter activity,molecular_function
64897,GO:0015212,"Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.",cytidine transmembrane transporter activity,molecular_function
64898,GO:0015213,"Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.",uridine transmembrane transporter activity,molecular_function
64899,GO:0015214,"Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.",pyrimidine nucleoside transmembrane transporter activity,molecular_function
64900,GO:0015215,"Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.",nucleotide transmembrane transporter activity,molecular_function
64901,GO:0015216,"Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.",purine nucleotide transmembrane transporter activity,molecular_function
64902,GO:0015217,"Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.",ADP transmembrane transporter activity,molecular_function
64903,GO:0015218,"Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.",pyrimidine nucleotide transmembrane transporter activity,molecular_function
64904,GO:0015220,Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.,choline transmembrane transporter activity,molecular_function
64905,GO:0015221,"Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.",lipopolysaccharide transmembrane transporter activity,molecular_function
64906,GO:0015224,"Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.",biopterin transmembrane transporter activity,molecular_function
64907,GO:0015225,"Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.",biotin transmembrane transporter activity,molecular_function
64908,GO:0015226,Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.,carnitine transmembrane transporter activity,molecular_function
64909,GO:0015227,Enables the transfer of O-acyl-L-carnitine from one side of a membrane to the other. O-acyl-L-carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.,O-acyl-L-carnitine transmembrane transporter activity,molecular_function
64910,GO:0015228,"Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A transmembrane transporter activity,molecular_function
64911,GO:0015229,"Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.",L-ascorbic acid transmembrane transporter activity,molecular_function
64912,GO:0015230,"Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.",FAD transmembrane transporter activity,molecular_function
64913,GO:0015231,"Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.",5-formyltetrahydrofolate transmembrane transporter activity,molecular_function
64914,GO:0015232,Enables the transfer of heme from one side of a membrane to the other.,heme transmembrane transporter activity,molecular_function
64915,GO:0015233,"Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.",pantothenate transmembrane transporter activity,molecular_function
64916,GO:0015234,"Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine transmembrane transporter activity,molecular_function
64917,GO:0015243,Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.,cycloheximide transmembrane transporter activity,molecular_function
64918,GO:0015244,Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.,fluconazole transmembrane transporter activity,molecular_function
64919,GO:0015245,Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.,fatty acid transmembrane transporter activity,molecular_function
64920,GO:0015247,"Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.",aminophospholipid flippase activity,molecular_function
64921,GO:0015250,Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel.,water channel activity,molecular_function
64922,GO:0015252,Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.,proton channel activity,molecular_function
64923,GO:0015254,Enables the energy-independent facilitated diffusion of glycerol through a transmembrane aqueous pore or channel.,glycerol channel activity,molecular_function
64924,GO:0015264,Enables the energy-independent facilitated diffusion of methylammonium through a transmembrane aqueous pore or channel. Methylammonium is CH3NH2.,methylammonium channel activity,molecular_function
64925,GO:0015265,Enables the energy-independent facilitated diffusion of urea through a transmembrane aqueous pore or channel.,urea channel activity,molecular_function
64926,GO:0015267,Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.,channel activity,molecular_function
64927,GO:0015269,Enables the transmembrane transfer of a potassium cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts.,calcium-activated potassium channel activity,molecular_function
64928,GO:0015271,Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.,outward rectifier potassium channel activity,molecular_function
64929,GO:0015272,"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.",ATP-activated inward rectifier potassium channel activity,molecular_function
64930,GO:0015274,Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.,organellar voltage-gated chloride channel activity,molecular_function
64931,GO:0015275,Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.,"stretch-activated, monoatomic cation-selective, calcium channel activity",molecular_function
64932,GO:0015276,Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated monoatomic ion channel activity,molecular_function
64933,GO:0015277,"An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.",kainate selective glutamate receptor activity,molecular_function
64934,GO:0015278,Enables the transmembrane transfer of a calcium ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.,intracellularly gated calcium channel activity,molecular_function
64935,GO:0015279,A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.,store-operated calcium channel activity,molecular_function
64936,GO:0015280,Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated sodium channel activity,molecular_function
64937,GO:0015284,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).,fructose uniporter activity,molecular_function
64938,GO:0015288,"Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.",porin activity,molecular_function
64939,GO:0015291,"Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.",secondary active transmembrane transporter activity,molecular_function
64940,GO:0015292,Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.,uniporter activity,molecular_function
64941,GO:0015293,Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.,symporter activity,molecular_function
64942,GO:0015294,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).,solute:monoatomic cation symporter activity,molecular_function
64943,GO:0015295,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).,solute:proton symporter activity,molecular_function
64944,GO:0015296,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).,monoatomic anion:monoatomic cation symporter activity,molecular_function
64945,GO:0015297,Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).,antiporter activity,molecular_function
64946,GO:0015304,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) = D-glucose(in).,D-glucose uniporter activity,molecular_function
64947,GO:0015306,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).,sialate:monoatomic cation symporter activity,molecular_function
64948,GO:0015309,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).,cycloheximide:proton antiporter activity,molecular_function
64949,GO:0015310,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).,benomyl:proton antiporter activity,molecular_function
64950,GO:0015311,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).,monoamine:proton antiporter activity,molecular_function
64951,GO:0015312,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).,polyamine:proton antiporter activity,molecular_function
64952,GO:0015313,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).,fluconazole:proton antiporter activity,molecular_function
64953,GO:0015314,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).,aminotriazole:proton antiporter activity,molecular_function
64954,GO:0015315,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + phosphate(in) = organophosphate(in) +  phosphate(out).,organophosphate:phosphate antiporter activity,molecular_function
64955,GO:0015317,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).,phosphate:proton symporter activity,molecular_function
64956,GO:0015325,Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).,acetyl-CoA:CoA antiporter activity,molecular_function
64957,GO:0015327,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).,cystine:glutamate antiporter activity,molecular_function
64958,GO:0015330,Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity glutamine transmembrane transporter activity,molecular_function
64959,GO:0015333,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.",peptide:proton symporter activity,molecular_function
64960,GO:0015334,Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.,high-affinity oligopeptide transmembrane transporter activity,molecular_function
64961,GO:0015341,Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane according to the reaction H+(out) + Zn2+(in) = H+(in) + Zn2+(out). The activity is driven by proton motive force.,zinc efflux antiporter activity,molecular_function
64962,GO:0015343,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).,siderophore-iron transmembrane transporter activity,molecular_function
64963,GO:0015344,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).,siderophore uptake transmembrane transporter activity,molecular_function
64964,GO:0015345,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).,ferric enterobactin:proton symporter activity,molecular_function
64965,GO:0015346,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).,ferric triacetylfusarinine C:proton symporter activity,molecular_function
64966,GO:0015349,"Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.",thyroid hormone transmembrane transporter activity,molecular_function
64967,GO:0015350,"Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.",methotrexate transmembrane transporter activity,molecular_function
64968,GO:0015355,"Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.",secondary active monocarboxylate transmembrane transporter activity,molecular_function
64969,GO:0015360,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).,acetate:proton symporter activity,molecular_function
64970,GO:0015361,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity sodium:dicarboxylate symporter activity,molecular_function
64971,GO:0015362,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity sodium:dicarboxylate symporter activity,molecular_function
64972,GO:0015364,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + phosphate(in) = dicarboxylate(in) +  phosphate(out).,dicarboxylate:phosphate antiporter activity,molecular_function
64973,GO:0015366,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).,malate:proton symporter activity,molecular_function
64974,GO:0015367,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).,oxoglutarate:malate antiporter activity,molecular_function
64975,GO:0015368,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).,calcium:monoatomic cation antiporter activity,molecular_function
64976,GO:0015369,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).,calcium:proton antiporter activity,molecular_function
64977,GO:0015370,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).,solute:sodium symporter activity,molecular_function
64978,GO:0015371,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).,galactose:sodium symporter activity,molecular_function
64979,GO:0015373,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic anion(out) + Na+(out) = monoatomic anion(in) + Na+(in).,monoatomic anion:sodium symporter activity,molecular_function
64980,GO:0015374,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).,"neutral, basic amino acid:sodium:chloride symporter activity",molecular_function
64981,GO:0015375,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).,glycine:sodium symporter activity,molecular_function
64982,GO:0015377,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).,chloride:monoatomic cation symporter activity,molecular_function
64983,GO:0015378,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).,sodium:chloride symporter activity,molecular_function
64984,GO:0015379,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).,potassium:chloride symporter activity,molecular_function
64985,GO:0015381,"Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transpor...",high-affinity sulfate transmembrane transporter activity,molecular_function
64986,GO:0015382,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).,sodium:sulfate symporter activity,molecular_function
64987,GO:0015383,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).,sulfate:bicarbonate antiporter activity,molecular_function
64988,GO:0015385,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).,sodium:proton antiporter activity,molecular_function
64989,GO:0015386,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).,potassium:proton antiporter activity,molecular_function
64990,GO:0015387,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).,potassium:proton symporter activity,molecular_function
64991,GO:0015389,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenosine)(out) + Na+(out) = (pyrimidine nucleoside or adenosine)(in) + Na+(in).,pyrimidine- and adenosine-specific:sodium symporter activity,molecular_function
64992,GO:0015390,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).,purine-specific nucleoside:sodium symporter activity,molecular_function
64993,GO:0015391,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).,nucleobase:monoatomic cation symporter activity,molecular_function
64994,GO:0015394,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).,uridine:proton symporter activity,molecular_function
64995,GO:0015395,"Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.","nucleoside transmembrane transporter activity, down a concentration gradient",molecular_function
64996,GO:0015399,"Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical such as ATP hydrolysis, redox energy and photon energy.",primary active transmembrane transporter activity,molecular_function
64997,GO:0015401,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).,urea:sodium symporter activity,molecular_function
64998,GO:0015407,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.",ABC-type monosaccharide transporter activity,molecular_function
64999,GO:0015408,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).,ABC-type ferric iron transporter activity,molecular_function
65000,GO:0015410,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).,ABC-type manganese transporter activity,molecular_function
65001,GO:0015411,Enables the transfer of taurine from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).,ABC-type taurine transporter transporter activity,molecular_function
65002,GO:0015412,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).,ABC-type molybdate transporter activity,molecular_function
65003,GO:0015413,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).,ABC-type nickel transporter activity,molecular_function
65004,GO:0015414,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).,ABC-type nitrate transporter activity,molecular_function
65005,GO:0015415,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).,ATPase-coupled phosphate ion transmembrane transporter activity,molecular_function
65006,GO:0015416,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).",ABC-type phosphonate transporter activity,molecular_function
65007,GO:0015417,Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).,ABC-type polyamine transporter activity,molecular_function
65008,GO:0015418,Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H+ + phosphate + quaternary ammonium(in).,ABC-type quaternary ammonium compound transporting activity,molecular_function
65009,GO:0015419,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).,ABC-type sulfate transporter activity,molecular_function
65010,GO:0015420,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.,ABC-type vitamin B12 transporter activity,molecular_function
65011,GO:0015421,Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).,ABC-type oligopeptide transporter activity,molecular_function
65012,GO:0015422,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).,ABC-type oligosaccharide transporter activity,molecular_function
65013,GO:0015423,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).,ABC-type maltose transporter activity,molecular_function
65014,GO:0015424,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).,ABC-type amino acid transporter activity,molecular_function
65015,GO:0015425,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).,ATPase-coupled nonpolar-amino acid transporter activity,molecular_function
65016,GO:0015426,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).,ATPase-coupled polar amino acid-transporter activity,molecular_function
65017,GO:0015430,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).,ABC-type glycerol-3-phosphate transporter activity,molecular_function
65018,GO:0015431,Catalysis of the reaction: an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H+.,ABC-type glutathione S-conjugate transporter activity,molecular_function
65019,GO:0015432,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cholate(in) + ATP + H2O = cholate(out) + ADP + phosphate + H+.,ABC-type bile acid transporter activity,molecular_function
65020,GO:0015433,Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.,ABC-type peptide antigen transporter activity,molecular_function
65021,GO:0015434,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).,ABC-type cadmium transporter activity,molecular_function
65022,GO:0015436,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).,ABC-type capsular-polysaccharide transporter activity,molecular_function
65023,GO:0015437,"Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",lipopolysaccharide floppase activity,molecular_function
65024,GO:0015438,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).,ABC-type teichoic acid transporter activity,molecular_function
65025,GO:0015439,Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).,ABC-type heme transporter activity,molecular_function
65026,GO:0015440,"Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.",ABC-type peptide transporter activity,molecular_function
65027,GO:0015441,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).,ABC-type beta-glucan transporter activity,molecular_function
65028,GO:0015444,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) = ADP + phosphate + Mg2+(in).,P-type magnesium transporter activity,molecular_function
65029,GO:0015445,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) = ADP + phosphate + Ag+(out).,P-type silver transporter activity,molecular_function
65030,GO:0015446,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).,ATPase-coupled arsenite transmembrane transporter activity,molecular_function
65031,GO:0015450,"Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.",protein-transporting ATPase activity,molecular_function
65032,GO:0015451,"Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.",decarboxylation-driven active transmembrane transporter activity,molecular_function
65033,GO:0015452,"Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.",methyl transfer-driven active transmembrane transporter activity,molecular_function
65034,GO:0015453,"Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.",oxidoreduction-driven active transmembrane transporter activity,molecular_function
65035,GO:0015454,"Active transport of an ion across a membrane, driven by light.",light-driven active monoatomic ion transmembrane transporter activity,molecular_function
65036,GO:0015459,Binds to and modulates the activity of a potassium channel.,potassium channel regulator activity,molecular_function
65037,GO:0015462,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).,ABC-type protein transporter activity,molecular_function
65038,GO:0015464,Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,acetylcholine receptor activity,molecular_function
65039,GO:0015467,"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.",G-protein activated inward rectifier potassium channel activity,molecular_function
65040,GO:0015471,"Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.",nucleoside-specific channel forming porin activity,molecular_function
65041,GO:0015473,A porin that acts in the assembly of fimbria together with fimbrial chaperone.,fimbrial usher porin activity,molecular_function
65042,GO:0015474,"Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.",autotransporter activity,molecular_function
65043,GO:0015478,"Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.",oligosaccharide transporting porin activity,molecular_function
65044,GO:0015481,"Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative b...",maltose transporting porin activity,molecular_function
65045,GO:0015483,"Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly...",long-chain fatty acid transporting porin activity,molecular_function
65046,GO:0015485,"Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",cholesterol binding,molecular_function
65047,GO:0015486,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.",glycoside-pentoside-hexuronide:cation symporter activity,molecular_function
65048,GO:0015487,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).,melibiose:monoatomic cation symporter activity,molecular_function
65049,GO:0015488,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).,glucuronide:cation symporter activity,molecular_function
65050,GO:0015489,"Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.",putrescine transmembrane transporter activity,molecular_function
65051,GO:0015492,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).,phenylalanine:proton symporter activity,molecular_function
65052,GO:0015493,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).,lysine:proton symporter activity,molecular_function
65053,GO:0015494,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).,aromatic amino acid:proton symporter activity,molecular_function
65054,GO:0015495,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).,gamma-aminobutyric acid:proton symporter activity,molecular_function
65055,GO:0015496,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).,putrescine:ornithine antiporter activity,molecular_function
65056,GO:0015498,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).,pantothenate:sodium symporter activity,molecular_function
65057,GO:0015499,"Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.",formate transmembrane transporter activity,molecular_function
65058,GO:0015501,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).,glutamate:sodium symporter activity,molecular_function
65059,GO:0015503,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.",glutathione-regulated potassium exporter activity,molecular_function
65060,GO:0015504,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).,cytosine:proton symporter activity,molecular_function
65061,GO:0015505,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).,uracil:monoatomic cation symporter activity,molecular_function
65062,GO:0015506,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).,nucleoside:proton symporter activity,molecular_function
65063,GO:0015513,"Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.",high-affinity secondary active nitrite transmembrane transporter activity,molecular_function
65064,GO:0015514,Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.,nitrite efflux transmembrane transporter activity,molecular_function
65065,GO:0015515,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).,citrate:succinate antiporter activity,molecular_function
65066,GO:0015516,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).,tartrate:succinate antiporter activity,molecular_function
65067,GO:0015517,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).,galactose:proton symporter activity,molecular_function
65068,GO:0015518,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).,arabinose:proton symporter activity,molecular_function
65069,GO:0015519,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).,D-xylose:proton symporter activity,molecular_function
65070,GO:0015520,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).,tetracycline:proton antiporter activity,molecular_function
65071,GO:0015526,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + phosphate(in) = hexose phosphate(in) +  phosphate(out).,hexose-phosphate:phosphate antiporter activity,molecular_function
65072,GO:0015527,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + phosphate(in) = glycerol phosphate(in) + phosphate(out).,glycerol-phosphate:phosphate antiporter activity,molecular_function
65073,GO:0015528,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).,lactose:proton symporter activity,molecular_function
65074,GO:0015529,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).,raffinose:proton symporter activity,molecular_function
65075,GO:0015530,Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.,shikimate transmembrane transporter activity,molecular_function
65076,GO:0015531,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).,citrate:proton symporter activity,molecular_function
65077,GO:0015532,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).,alpha-ketoglutarate:proton symporter activity,molecular_function
65078,GO:0015533,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).,shikimate:proton symporter activity,molecular_function
65079,GO:0015535,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).,fucose:proton symporter activity,molecular_function
65080,GO:0015537,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).,xanthosine:proton symporter activity,molecular_function
65081,GO:0015538,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).,sialic acid:proton symporter activity,molecular_function
65082,GO:0015539,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.,hexuronate:monoatomic cation symporter activity,molecular_function
65083,GO:0015540,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).,3-hydroxyphenyl propionate:proton symporter activity,molecular_function
65084,GO:0015541,Enables the transfer of cyanate from one side of a membrane to the other.,secondary active cyanate transmembrane transporter activity,molecular_function
65085,GO:0015544,Enables the transfer of phenyl propionate from one side of a membrane to the other.,phenyl propionate uniporter activity,molecular_function
65086,GO:0015545,Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.,bicyclomycin transmembrane transporter activity,molecular_function
65087,GO:0015546,Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group.,sulfathiazole transmembrane transporter activity,molecular_function
65088,GO:0015550,Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.,galacturonate transmembrane transporter activity,molecular_function
65089,GO:0015551,Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.,3-hydroxyphenyl propanoate transmembrane transporter activity,molecular_function
65090,GO:0015552,Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.,propionate transmembrane transporter activity,molecular_function
65091,GO:0015553,"Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.",xanthosine transmembrane transporter activity,molecular_function
65092,GO:0015554,"Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.",tartrate transmembrane transporter activity,molecular_function
65093,GO:0015556,Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.,C4-dicarboxylate transmembrane transporter activity,molecular_function
65094,GO:0015558,"Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.",secondary active p-aminobenzoyl-glutamate transmembrane transporter activity,molecular_function
65095,GO:0015561,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).,rhamnose:proton symporter activity,molecular_function
65096,GO:0015562,Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.,efflux transmembrane transporter activity,molecular_function
65097,GO:0015565,Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.,threonine efflux transmembrane transporter activity,molecular_function
65098,GO:0015567,Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.,alkane transmembrane transporter activity,molecular_function
65099,GO:0015568,"Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.",L-idonate transmembrane transporter activity,molecular_function
65100,GO:0015571,"Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.",N-acetylgalactosamine transmembrane transporter activity,molecular_function
65101,GO:0015572,"Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.",N-acetylglucosamine transmembrane transporter activity,molecular_function
65102,GO:0015573,"Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.",beta-glucoside transmembrane transporter activity,molecular_function
65103,GO:0015574,"Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.",trehalose transmembrane transporter activity,molecular_function
65104,GO:0015575,Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.,mannitol transmembrane transporter activity,molecular_function
65105,GO:0015576,"Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.",sorbitol transmembrane transporter activity,molecular_function
65106,GO:0015577,Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.,galactitol transmembrane transporter activity,molecular_function
65107,GO:0015578,"Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.",mannose transmembrane transporter activity,molecular_function
65108,GO:0015591,"Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.",D-ribose transmembrane transporter activity,molecular_function
65109,GO:0015592,Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.,methylgalactoside transmembrane transporter activity,molecular_function
65110,GO:0015594,Catalysis of the reaction: putrescine(out) + ATP + H2O = putrescine(in) + ADP + phosphate + H+.,ABC-type putrescine transporter activity,molecular_function
65111,GO:0015599,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + ATP + H2O = L-glutamine(in) + ADP + phosphate + H+.,ATPase-coupled L-glutamine transmembrane transporter activity,molecular_function
65112,GO:0015603,Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.,iron chelate transmembrane transporter activity,molecular_function
65113,GO:0015605,Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.,organophosphate ester transmembrane transporter activity,molecular_function
65114,GO:0015606,"Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.",spermidine transmembrane transporter activity,molecular_function
65115,GO:0015607,Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) = ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.,ABC-type fatty-acyl-CoA transporter activity,molecular_function
65116,GO:0015611,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) = ADP + phosphate + D-ribose(in).,ABC-type D-ribose transporter activity,molecular_function
65117,GO:0015612,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) = ADP + phosphate + L-arabinose(in).,ABC-type L-arabinose transporter activity,molecular_function
65118,GO:0015614,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) = ADP + phosphate + D-xylose(in).,ABC-type D-xylose transporter activity,molecular_function
65119,GO:0015615,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) = ADP + phosphate + D-allose(in).,ABC-type D-allose transporter activity,molecular_function
65120,GO:0015616,"Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis.",DNA translocase activity,molecular_function
65121,GO:0015620,Enables the transfer of ferric-enterobactin from one side of a membrane to the other.,ferric-enterobactin transmembrane transporter activity,molecular_function
65122,GO:0015621,Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.,ferric triacetylfusarinine C transmembrane transporter activity,molecular_function
65123,GO:0015624,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).,ABC-type ferric-enterobactin transporter activity,molecular_function
65124,GO:0015625,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).,ABC-type ferric hydroxamate transporter activity,molecular_function
65125,GO:0015626,"Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.",L-diaminopimelate transmembrane transporter activity,molecular_function
65126,GO:0015627,"A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.",type II protein secretion system complex,cellular_component
65127,GO:0015628,The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.,protein secretion by the type II secretion system,biological_process
65128,GO:0015629,The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.,actin cytoskeleton,cellular_component
65129,GO:0015630,The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.,microtubule cytoskeleton,cellular_component
65130,GO:0015631,"Binding to monomeric or multimeric forms of tubulin, including microtubules.",tubulin binding,molecular_function
65131,GO:0015633,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).,ABC-type zinc transporter activity,molecular_function
65132,GO:0015636,Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid transmembrane transporter activity,molecular_function
65133,GO:0015638,Enables the transfer of a microcin from one side of a membrane to the other.,microcin transmembrane transporter activity,molecular_function
65134,GO:0015640,Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.,peptidoglycan peptide transmembrane transporter activity,molecular_function
65135,GO:0015643,"Binding to a toxic substance, a poisonous substance that causes damage to biological systems.",toxic substance binding,molecular_function
65136,GO:0015645,"Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.",fatty acid ligase activity,molecular_function
65137,GO:0015647,"Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.",peptidoglycan transmembrane transporter activity,molecular_function
65138,GO:0015648,"Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.",lipid-linked peptidoglycan transporter activity,molecular_function
65139,GO:0015649,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).,2-keto-3-deoxygluconate:proton symporter activity,molecular_function
65140,GO:0015650,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).,lactate:proton symporter activity,molecular_function
65141,GO:0015651,Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.,quaternary ammonium group transmembrane transporter activity,molecular_function
65142,GO:0015652,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).,quaternary ammonium group:proton symporter activity,molecular_function
65143,GO:0015653,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).,glycine betaine:proton symporter activity,molecular_function
65144,GO:0015654,Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.,tellurite transmembrane transporter activity,molecular_function
65145,GO:0015655,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).,alanine:sodium symporter activity,molecular_function
65146,GO:0015657,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).,branched-chain amino acid:sodium symporter activity,molecular_function
65147,GO:0015658,Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.,branched-chain amino acid transmembrane transporter activity,molecular_function
65148,GO:0015660,Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.,formate efflux transmembrane transporter activity,molecular_function
65149,GO:0015661,Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.,L-lysine efflux transmembrane transporter activity,molecular_function
65150,GO:0015662,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.",P-type ion transporter activity,molecular_function
65151,GO:0015663,"Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.",nicotinamide mononucleotide transmembrane transporter activity,molecular_function
65152,GO:0015665,Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.,alcohol transmembrane transporter activity,molecular_function
65153,GO:0015666,"Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.",restriction endodeoxyribonuclease activity,molecular_function
65154,GO:0015667,Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.,site-specific DNA-methyltransferase (cytosine-N4-specific) activity,molecular_function
65155,GO:0015668,Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.,type III site-specific deoxyribonuclease activity,molecular_function
65156,GO:0015669,"The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",gas transport,biological_process
65157,GO:0015670,"The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",carbon dioxide transport,biological_process
65158,GO:0015671,"The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",oxygen transport,biological_process
65159,GO:0015673,"The directed movement of silver (Ag+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",silver ion transport,biological_process
65160,GO:0015675,"The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nickel cation transport,biological_process
65161,GO:0015676,"The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",vanadium ion transport,biological_process
65162,GO:0015677,The directed movement of copper ions into a cell or organelle.,copper ion import,biological_process
65163,GO:0015679,The directed movement of copper ions across the plasma membrane.,plasma membrane copper ion transport,biological_process
65164,GO:0015685,"A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.",ferric-enterobactin import into cell,biological_process
65165,GO:0015686,"The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ferric triacetylfusarinine C import into cell,biological_process
65166,GO:0015687,"A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors.",ferric-hydroxamate import into cell,biological_process
65167,GO:0015689,"The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.",molybdate ion transport,biological_process
65168,GO:0015690,"The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",aluminum cation transport,biological_process
65169,GO:0015691,"The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cadmium ion transport,biological_process
65170,GO:0015692,"The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lead ion transport,biological_process
65171,GO:0015693,"The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",magnesium ion transport,biological_process
65172,GO:0015694,"The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",mercury ion transport,biological_process
65173,GO:0015697,"The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.",quaternary ammonium group transport,biological_process
65174,GO:0015698,"The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.",inorganic anion transport,biological_process
65175,GO:0015699,"The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",antimonite transmembrane transport,biological_process
65176,GO:0015700,"The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",arsenite transport,biological_process
65177,GO:0015701,"The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",bicarbonate transport,biological_process
65178,GO:0015702,"The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",chlorate transport,biological_process
65179,GO:0015703,"The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",chromate transport,biological_process
65180,GO:0015704,"The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cyanate transport,biological_process
65181,GO:0015705,"The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",iodide transport,biological_process
65182,GO:0015706,"The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nitrate transmembrane transport,biological_process
65183,GO:0015707,"The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nitrite transport,biological_process
65184,GO:0015708,"The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.",silicic acid import across plasma membrane,biological_process
65185,GO:0015709,"The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",thiosulfate transport,biological_process
65186,GO:0015710,"The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tellurite transport,biological_process
65187,GO:0015712,"The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hexose phosphate transport,biological_process
65188,GO:0015713,"The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other.",phosphoglycerate transmembrane transport,biological_process
65189,GO:0015714,"The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",phosphoenolpyruvate transport,biological_process
65190,GO:0015715,"The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nucleotide-sulfate transport,biological_process
65191,GO:0015716,"The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).",organic phosphonate transport,biological_process
65192,GO:0015717,"The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",triose phosphate transport,biological_process
65193,GO:0015718,"The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",monocarboxylic acid transport,biological_process
65194,GO:0015719,"The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",allantoate transport,biological_process
65195,GO:0015720,"The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",allantoin transport,biological_process
65196,GO:0015721,"The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",bile acid and bile salt transport,biological_process
65197,GO:0015722,"Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.",canalicular bile acid transport,biological_process
65198,GO:0015723,"The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",bilirubin transport,biological_process
65199,GO:0015724,"The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",formate transport,biological_process
65200,GO:0015726,"The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.",L-idonate transmembrane transport,biological_process
65201,GO:0015727,"The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.",lactate transport,biological_process
65202,GO:0015728,"The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",mevalonate transport,biological_process
65203,GO:0015729,"The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",oxaloacetate transport,biological_process
65204,GO:0015730,"The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",propanoate transmembrane transport,biological_process
65205,GO:0015731,"The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",3-hydroxyphenyl propanoate transport,biological_process
65206,GO:0015732,"The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",prostaglandin transport,biological_process
65207,GO:0015733,"The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other.",shikimate transmembrane transport,biological_process
65208,GO:0015734,"The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",taurine transmembrane transport,biological_process
65209,GO:0015735,"The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other.",uronic acid transmembrane transport,biological_process
65210,GO:0015736,"The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.",hexuronate transmembrane transport,biological_process
65211,GO:0015737,"The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other.",galacturonate transmembrane transport,biological_process
65212,GO:0015738,"The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other.",glucuronate transmembrane transport,biological_process
65213,GO:0015739,"The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sialic acid transport,biological_process
65214,GO:0015740,"The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.",C4-dicarboxylate transport,biological_process
65215,GO:0015741,"The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",fumarate transport,biological_process
65216,GO:0015742,"The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",alpha-ketoglutarate transport,biological_process
65217,GO:0015743,"The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",malate transport,biological_process
65218,GO:0015744,"The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",succinate transport,biological_process
65219,GO:0015745,"The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other.",tartrate transmembrane transport,biological_process
65220,GO:0015746,"The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboxylate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",citrate transport,biological_process
65221,GO:0015747,"The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",urate transport,biological_process
65222,GO:0015748,"The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.",organophosphate ester transport,biological_process
65223,GO:0015749,"The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.",monosaccharide transmembrane transport,biological_process
65224,GO:0015750,"The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.",pentose transmembrane transport,biological_process
65225,GO:0015751,"The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other.",arabinose transmembrane transport,biological_process
65226,GO:0015752,"The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.",D-ribose transmembrane transport,biological_process
65227,GO:0015753,"The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.",D-xylose transmembrane transport,biological_process
65228,GO:0015754,"The process in which D-allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.",D-allose transmembrane transport,biological_process
65229,GO:0015755,"The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.",fructose transmembrane transport,biological_process
65230,GO:0015756,"The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.",fucose transmembrane transport,biological_process
65231,GO:0015757,"The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.",galactose transmembrane transport,biological_process
65232,GO:0015759,"The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.",beta-glucoside transport,biological_process
65233,GO:0015760,"The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.",glucose-6-phosphate transport,biological_process
65234,GO:0015761,"The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.",mannose transmembrane transport,biological_process
65235,GO:0015762,"The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.",rhamnose transmembrane transport,biological_process
65236,GO:0015763,"The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.",N-acetylgalactosamine transport,biological_process
65237,GO:0015764,"The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",N-acetylglucosamine transport,biological_process
65238,GO:0015765,"The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.",methylgalactoside transport,biological_process
65239,GO:0015766,"The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.",disaccharide transport,biological_process
65240,GO:0015767,"The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.",lactose transport,biological_process
65241,GO:0015768,"The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.",maltose transport,biological_process
65242,GO:0015769,"The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.",melibiose transport,biological_process
65243,GO:0015770,"The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.",sucrose transport,biological_process
65244,GO:0015771,"The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.",trehalose transport,biological_process
65245,GO:0015772,"The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.",oligosaccharide transport,biological_process
65246,GO:0015773,"The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.",raffinose transport,biological_process
65247,GO:0015774,"The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.",polysaccharide transport,biological_process
65248,GO:0015775,"The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.",beta-glucan transport,biological_process
65249,GO:0015776,"The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.",capsular polysaccharide transport,biological_process
65250,GO:0015777,"The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.",teichoic acid transport,biological_process
65251,GO:0015778,The directed movement of hexuronide across a membrane. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.,hexuronide transmembrane transport,biological_process
65252,GO:0015779,"The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.",glucuronoside transport,biological_process
65253,GO:0015780,"The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.",nucleotide-sugar transmembrane transport,biological_process
65254,GO:0015782,"The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",CMP-N-acetylneuraminate transmembrane transport,biological_process
65255,GO:0015783,"The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.",GDP-fucose transmembrane transport,biological_process
65256,GO:0015786,The process in which UDP-glucose is transported across a membrane.,UDP-glucose transmembrane transport,biological_process
65257,GO:0015787,"The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.",UDP-glucuronate transmembrane transport,biological_process
65258,GO:0015789,"The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylgalactosamine transmembrane transport,biological_process
65259,GO:0015790,"The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.",UDP-xylose transmembrane transport,biological_process
65260,GO:0015791,"The directed movement of polyols, any polyhydric alcohol, across a membrane.",polyol transmembrane transport,biological_process
65261,GO:0015792,"The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.",arabinitol transmembrane transport,biological_process
65262,GO:0015793,"The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.",glycerol transmembrane transport,biological_process
65263,GO:0015794,The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol.,glycerol-3-phosphate transmembrane transport,biological_process
65264,GO:0015795,"The directed movement of sorbitol across a membrane. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.",sorbitol transmembrane transport,biological_process
65265,GO:0015796,The directed movement of galactitol across a membrane. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.,galactitol transmembrane transport,biological_process
65266,GO:0015797,The directed movement of mannitol across a membrane. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.,mannitol transmembrane transport,biological_process
65267,GO:0015798,"The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.",myo-inositol transport,biological_process
65268,GO:0015799,"The directed movement of 1,3-propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.","propane 1,3-diol transport",biological_process
65269,GO:0015800,"The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",acidic amino acid transport,biological_process
65270,GO:0015801,"The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",aromatic amino acid transport,biological_process
65271,GO:0015802,"The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",basic amino acid transport,biological_process
65272,GO:0015803,"The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.",branched-chain amino acid transport,biological_process
65273,GO:0015804,"The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",neutral amino acid transport,biological_process
65274,GO:0015805,"The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",S-adenosyl-L-methionine transport,biological_process
65275,GO:0015806,"The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",S-methylmethionine transport,biological_process
65276,GO:0015807,"The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-amino acid transport,biological_process
65277,GO:0015808,"The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-alanine transport,biological_process
65278,GO:0015810,"The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other.",aspartate transmembrane transport,biological_process
65279,GO:0015811,"The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-cystine transport,biological_process
65280,GO:0015812,"The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",gamma-aminobutyric acid transport,biological_process
65281,GO:0015813,The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore.,L-glutamate transmembrane transport,biological_process
65282,GO:0015814,"The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",p-aminobenzoyl-glutamate transport,biological_process
65283,GO:0015816,"The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycine transport,biological_process
65284,GO:0015817,"The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",histidine transport,biological_process
65285,GO:0015818,"The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",isoleucine transport,biological_process
65286,GO:0015819,"The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lysine transport,biological_process
65287,GO:0015820,"The directed movement of L-leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-leucine transport,biological_process
65288,GO:0015821,"The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",methionine transport,biological_process
65289,GO:0015822,"The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ornithine transport,biological_process
65290,GO:0015823,"The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",phenylalanine transport,biological_process
65291,GO:0015824,"The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",proline transport,biological_process
65292,GO:0015825,"The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-serine transport,biological_process
65293,GO:0015826,"The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",threonine transport,biological_process
65294,GO:0015827,"The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tryptophan transport,biological_process
65295,GO:0015828,"The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tyrosine transport,biological_process
65296,GO:0015829,"The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",valine transport,biological_process
65297,GO:0015830,"The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",diaminopimelate transport,biological_process
65298,GO:0015833,"The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",peptide transport,biological_process
65299,GO:0015834,"The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.",peptidoglycan-associated peptide transport,biological_process
65300,GO:0015835,"The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",peptidoglycan transport,biological_process
65301,GO:0015836,"The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lipid-linked peptidoglycan transport,biological_process
65302,GO:0015837,"The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",amine transport,biological_process
65303,GO:0015838,"The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",amino-acid betaine transport,biological_process
65304,GO:0015839,"The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cadaverine transport,biological_process
65305,GO:0015840,"The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.",urea transport,biological_process
65306,GO:0015841,"The directed movement of amines into, out of or within chromaffin granules.",chromaffin granule amine transport,biological_process
65307,GO:0015842,"The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.",aminergic neurotransmitter loading into synaptic vesicle,biological_process
65308,GO:0015843,"The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",methylammonium transport,biological_process
65309,GO:0015846,"The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",polyamine transport,biological_process
65310,GO:0015847,"The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.",putrescine transport,biological_process
65311,GO:0015848,"The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",spermidine transport,biological_process
65312,GO:0015849,"The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",organic acid transport,biological_process
65313,GO:0015850,"The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.",organic hydroxy compound transport,biological_process
65314,GO:0015851,"The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nucleobase transport,biological_process
65315,GO:0015853,"The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",adenine transport,biological_process
65316,GO:0015854,"The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",guanine transport,biological_process
65317,GO:0015855,"The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",pyrimidine nucleobase transport,biological_process
65318,GO:0015856,"The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cytosine transport,biological_process
65319,GO:0015857,"The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",uracil transport,biological_process
65320,GO:0015858,"The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nucleoside transport,biological_process
65321,GO:0015859,"The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.",intracellular nucleoside transport,biological_process
65322,GO:0015860,The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.,purine nucleoside transmembrane transport,biological_process
65323,GO:0015861,"The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cytidine transport,biological_process
65324,GO:0015862,"The directed movement of uridine, uracil riboside, across a lipid bilayer, by means of some agent such as a transporter or pore.",uridine transmembrane transport,biological_process
65325,GO:0015863,"The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",xanthosine transport,biological_process
65326,GO:0015864,"The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",pyrimidine nucleoside transport,biological_process
65327,GO:0015865,"The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.",purine nucleotide transport,biological_process
65328,GO:0015866,"The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ADP transport,biological_process
65329,GO:0015867,"The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ATP transport,biological_process
65330,GO:0015868,"The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.",purine ribonucleotide transport,biological_process
65331,GO:0015869,"The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",protein-DNA complex transport,biological_process
65332,GO:0015870,"The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.",acetylcholine transport,biological_process
65333,GO:0015871,"The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.",choline transport,biological_process
65334,GO:0015876,"The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.",acetyl-CoA transport,biological_process
65335,GO:0015877,"The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.",biopterin transport,biological_process
65336,GO:0015878,"The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.",biotin transport,biological_process
65337,GO:0015879,"The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.",carnitine transport,biological_process
65338,GO:0015880,"The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A transport,biological_process
65339,GO:0015881,The directed movement of creatine across a membrane.,creatine transmembrane transport,biological_process
65340,GO:0015882,"The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.",L-ascorbic acid transmembrane transport,biological_process
65341,GO:0015883,"The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.",FAD transport,biological_process
65342,GO:0015884,"The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.",folic acid transport,biological_process
65343,GO:0015885,"The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.",5-formyltetrahydrofolate transport,biological_process
65344,GO:0015886,"The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",heme transport,biological_process
65345,GO:0015887,"The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.",pantothenate transmembrane transport,biological_process
65346,GO:0015888,"The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine transport,biological_process
65347,GO:0015889,"The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cobalamin transport,biological_process
65348,GO:0015890,"The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.",nicotinamide mononucleotide transport,biological_process
65349,GO:0015891,"The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",siderophore transport,biological_process
65350,GO:0015895,"The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.",alkane transport,biological_process
65351,GO:0015899,"The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.",aminotriazole transport,biological_process
65352,GO:0015901,"The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.",cycloheximide transport,biological_process
65353,GO:0015903,"The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.",fluconazole transport,biological_process
65354,GO:0015904,The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).,tetracycline transmembrane transport,biological_process
65355,GO:0015905,"The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.",bicyclomycin transmembrane transport,biological_process
65356,GO:0015908,"The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.",fatty acid transport,biological_process
65357,GO:0015909,"The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty acid transport,biological_process
65358,GO:0015910,The directed movement of a long-chain fatty acid into a peroxisome. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid import into peroxisome,biological_process
65359,GO:0015911,"The directed movement of a long-chain fatty acid from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty acid import across plasma membrane,biological_process
65360,GO:0015912,"The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.",short-chain fatty acid transport,biological_process
65361,GO:0015913,The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid transmembrane transport,biological_process
65362,GO:0015914,"The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.",phospholipid transport,biological_process
65363,GO:0015916,"The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A).",fatty-acyl-CoA transport,biological_process
65364,GO:0015917,"The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.",aminophospholipid transport,biological_process
65365,GO:0015918,"The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",sterol transport,biological_process
65366,GO:0015919,"The directed movement of substances to, from or across the peroxisomal membrane.",peroxisomal membrane transport,biological_process
65367,GO:0015920,"The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.",lipopolysaccharide transport,biological_process
65368,GO:0015923,"Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.",mannosidase activity,molecular_function
65369,GO:0015924,Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.,mannosyl-oligosaccharide mannosidase activity,molecular_function
65370,GO:0015925,"Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.",galactosidase activity,molecular_function
65371,GO:0015926,"Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.",glucosidase activity,molecular_function
65372,GO:0015927,Catalysis of the hydrolysis of trehalose or a trehalose derivative.,trehalase activity,molecular_function
65373,GO:0015928,"Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.",fucosidase activity,molecular_function
65374,GO:0015929,Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.,hexosaminidase activity,molecular_function
65375,GO:0015930,"Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.",glutamate synthase activity,molecular_function
65376,GO:0015931,"The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nucleobase-containing compound transport,biological_process
65377,GO:0015932,"Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.",nucleobase-containing compound transmembrane transporter activity,molecular_function
65378,GO:0015934,"The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).",large ribosomal subunit,cellular_component
65379,GO:0015935,The smaller of the two subunits of a ribosome.,small ribosomal subunit,cellular_component
65380,GO:0015936,"The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A metabolic process,biological_process
65381,GO:0015937,"The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A biosynthetic process,biological_process
65382,GO:0015938,"The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A catabolic process,biological_process
65383,GO:0015939,"The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.",pantothenate metabolic process,biological_process
65384,GO:0015940,"The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.",pantothenate biosynthetic process,biological_process
65385,GO:0015941,"The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.",pantothenate catabolic process,biological_process
65386,GO:0015942,"The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.",formate metabolic process,biological_process
65387,GO:0015943,"The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.",formate biosynthetic process,biological_process
65388,GO:0015944,The chemical reactions and pathways by which formate is converted to CO2.,formate oxidation,biological_process
65389,GO:0015945,"The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.",methanol metabolic process,biological_process
65390,GO:0015946,The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.,methanol oxidation,biological_process
65391,GO:0015947,"The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.",methane metabolic process,biological_process
65392,GO:0015948,"The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.",methanogenesis,biological_process
65393,GO:0015949,"The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.",nucleobase-containing small molecule interconversion,biological_process
65394,GO:0015950,The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.,purine nucleotide interconversion,biological_process
65395,GO:0015951,The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.,purine ribonucleotide interconversion,biological_process
65396,GO:0015952,The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.,purine deoxyribonucleotide interconversion,biological_process
65397,GO:0015953,The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.,pyrimidine nucleotide interconversion,biological_process
65398,GO:0015954,The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.,pyrimidine ribonucleotide interconversion,biological_process
65399,GO:0015955,The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.,pyrimidine deoxyribonucleotide interconversion,biological_process
65400,GO:0015957,"The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.",bis(5'-nucleosidyl) oligophosphate biosynthetic process,biological_process
65401,GO:0015958,"The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.",bis(5'-nucleosidyl) oligophosphate catabolic process,biological_process
65402,GO:0015959,"The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.",diadenosine polyphosphate metabolic process,biological_process
65403,GO:0015960,"The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.",diadenosine polyphosphate biosynthetic process,biological_process
65404,GO:0015961,"The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.",diadenosine polyphosphate catabolic process,biological_process
65405,GO:0015963,"The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.",diadenosine triphosphate biosynthetic process,biological_process
65406,GO:0015964,"The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.",diadenosine triphosphate catabolic process,biological_process
65407,GO:0015966,"The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.",diadenosine tetraphosphate biosynthetic process,biological_process
65408,GO:0015967,"The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.",diadenosine tetraphosphate catabolic process,biological_process
65409,GO:0015968,"A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.",stringent response,biological_process
65410,GO:0015969,"The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.",guanosine tetraphosphate metabolic process,biological_process
65411,GO:0015970,"The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.",guanosine tetraphosphate biosynthetic process,biological_process
65412,GO:0015971,"The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.",guanosine tetraphosphate catabolic process,biological_process
65413,GO:0015972,"The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.",guanosine pentaphosphate metabolic process,biological_process
65414,GO:0015973,"The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.",guanosine pentaphosphate biosynthetic process,biological_process
65415,GO:0015974,"The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.",guanosine pentaphosphate catabolic process,biological_process
65416,GO:0015975,The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.,energy derivation by oxidation of reduced inorganic compounds,biological_process
65417,GO:0015976,"A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing s...",carbon utilization,biological_process
65418,GO:0015977,A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).,carbon fixation,biological_process
65419,GO:0015979,"The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.",photosynthesis,biological_process
65420,GO:0015980,The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.,energy derivation by oxidation of organic compounds,biological_process
65421,GO:0015985,The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.,"energy coupled proton transport, down electrochemical gradient",biological_process
65422,GO:0015986,The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a membrane to generate an electrochemical gradient (proton-motive force).,proton motive force-driven ATP synthesis,biological_process
65423,GO:0015987,The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.,GTP synthesis coupled proton transport,biological_process
65424,GO:0015988,"The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.","energy coupled proton transmembrane transport, against electrochemical gradient",biological_process
65425,GO:0015990,"The transport of protons against an electrochemical gradient, using energy from electron transport.",electron transport coupled proton transport,biological_process
65426,GO:0015994,"The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.",chlorophyll metabolic process,biological_process
65427,GO:0015995,"The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.",chlorophyll biosynthetic process,biological_process
65428,GO:0015996,"The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.",chlorophyll catabolic process,biological_process
65429,GO:0016004,"Binds to and increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.",phospholipase activator activity,molecular_function
65430,GO:0016005,Binds to and increases the activity of the enzyme phospholipase A2.,phospholipase A2 activator activity,molecular_function
65431,GO:0016006,A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.,Nebenkern,cellular_component
65432,GO:0016007,The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.,mitochondrial derivative,cellular_component
65433,GO:0016008,The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.,major mitochondrial derivative,cellular_component
65434,GO:0016009,The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.,minor mitochondrial derivative,cellular_component
65435,GO:0016010,"A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.",dystrophin-associated glycoprotein complex,cellular_component
65436,GO:0016011,"A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.",dystroglycan complex,cellular_component
65437,GO:0016012,"A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.",sarcoglycan complex,cellular_component
65438,GO:0016013,"A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.",syntrophin complex,cellular_component
65439,GO:0016014,A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.,dystrobrevin complex,cellular_component
65440,GO:0016015,Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.,morphogen activity,molecular_function
65441,GO:0016018,"Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.",cyclosporin A binding,molecular_function
65442,GO:0016019,Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response.,peptidoglycan immune receptor activity,molecular_function
65443,GO:0016020,A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.,membrane,cellular_component
65444,GO:0016024,"The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.",CDP-diacylglycerol biosynthetic process,biological_process
65445,GO:0016027,A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.,inaD signaling complex,cellular_component
65446,GO:0016028,The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.,rhabdomere,cellular_component
65447,GO:0016029,"A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.",subrhabdomeral cisterna,cellular_component
65448,GO:0016031,The process in which a tRNA is transported from the cytosol into the mitochondrial matrix.,tRNA import into mitochondrion,biological_process
65449,GO:0016032,"A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.",viral process,biological_process
65450,GO:0016034,Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.,maleylacetoacetate isomerase activity,molecular_function
65451,GO:0016035,"A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.",zeta DNA polymerase complex,cellular_component
65452,GO:0016036,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.",cellular response to phosphate starvation,biological_process
65453,GO:0016037,The reception of a photon by a cell.,light absorption,biological_process
65454,GO:0016038,"The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.",absorption of visible light,biological_process
65455,GO:0016039,"The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.",absorption of UV light,biological_process
65456,GO:0016040,Catalysis of the reaction: 2 L-glutamate + NAD+ = 2-oxoglutarate + L-glutamine + H+ + NADH.,glutamate synthase (NADH) activity,molecular_function
65457,GO:0016041,"Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH4+ = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH4+ + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.",glutamate synthase (ferredoxin) activity,molecular_function
65458,GO:0016042,"The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.",lipid catabolic process,biological_process
65459,GO:0016043,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",cellular component organization,biological_process
65460,GO:0016045,The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.,detection of bacterium,biological_process
65461,GO:0016046,The series of events in which a stimulus from a fungus is received and converted into a molecular signal.,detection of fungus,biological_process
65462,GO:0016048,The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.,detection of temperature stimulus,biological_process
65463,GO:0016049,The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.,cell growth,biological_process
65464,GO:0016050,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.",vesicle organization,biological_process
65465,GO:0016051,"The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate biosynthetic process,biological_process
65466,GO:0016052,"The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate catabolic process,biological_process
65467,GO:0016055,The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state.,Wnt signaling pathway,biological_process
65468,GO:0016056,"A G protein-coupled receptor signaling pathway that starts with an opsin being activated by a photon, and ending with the light signal being trasmitted through the synapses. The signal can be transmitted via different Galpha subunits types: Go, Gs, Gq, and Gt.",G protein-coupled opsin signaling pathway,biological_process
65469,GO:0016057,Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.,regulation of membrane potential in photoreceptor cell,biological_process
65470,GO:0016058,Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.,maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling,biological_process
65471,GO:0016059,The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).,negative regulation of opsin-mediated signaling pathway,biological_process
65472,GO:0016060,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating phototransduction signaling pathway. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.",negative regulation of phospholipase C-activating phototransduction signaling pathway,biological_process
65473,GO:0016063,"The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.",rhodopsin biosynthetic process,biological_process
65474,GO:0016064,"An immune response mediated by immunoglobulins, whether cell-bound or in solution.",immunoglobulin mediated immune response,biological_process
65475,GO:0016068,"An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.",type I hypersensitivity,biological_process
65476,GO:0016070,"The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.",RNA metabolic process,biological_process
65477,GO:0016071,"The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.",mRNA metabolic process,biological_process
65478,GO:0016072,"The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.",rRNA metabolic process,biological_process
65479,GO:0016073,"The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.",snRNA metabolic process,biological_process
65480,GO:0016074,"The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.",sno(s)RNA metabolic process,biological_process
65481,GO:0016075,"The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.",rRNA catabolic process,biological_process
65482,GO:0016076,"The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.",snRNA catabolic process,biological_process
65483,GO:0016077,"The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.",sno(s)RNA catabolic process,biological_process
65484,GO:0016078,"The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.",tRNA decay,biological_process
65485,GO:0016079,Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.,synaptic vesicle exocytosis,biological_process
65486,GO:0016082,"A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.",synaptic vesicle priming,biological_process
65487,GO:0016084,"The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.",myostimulatory hormone activity,molecular_function
65488,GO:0016085,"The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.",myoinhibitory hormone activity,molecular_function
65489,GO:0016087,"The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.",ecdysiostatic hormone activity,molecular_function
65490,GO:0016091,"The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.",prenol biosynthetic process,biological_process
65491,GO:0016092,"The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.",prenol catabolic process,biological_process
65492,GO:0016093,"The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.",polyprenol metabolic process,biological_process
65493,GO:0016094,"The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.",polyprenol biosynthetic process,biological_process
65494,GO:0016095,"The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.",polyprenol catabolic process,biological_process
65495,GO:0016098,"The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.",monoterpenoid metabolic process,biological_process
65496,GO:0016099,"The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.",monoterpenoid biosynthetic process,biological_process
65497,GO:0016100,"The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.",monoterpenoid catabolic process,biological_process
65498,GO:0016101,"The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.",diterpenoid metabolic process,biological_process
65499,GO:0016102,"The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.",diterpenoid biosynthetic process,biological_process
65500,GO:0016103,"The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.",diterpenoid catabolic process,biological_process
65501,GO:0016104,"The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.",triterpenoid biosynthetic process,biological_process
65502,GO:0016105,"The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.",triterpenoid catabolic process,biological_process
65503,GO:0016106,"The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.",sesquiterpenoid biosynthetic process,biological_process
65504,GO:0016107,"The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.",sesquiterpenoid catabolic process,biological_process
65505,GO:0016109,"The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.",tetraterpenoid biosynthetic process,biological_process
65506,GO:0016110,"The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.",tetraterpenoid catabolic process,biological_process
65507,GO:0016112,"The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.",polyterpenoid biosynthetic process,biological_process
65508,GO:0016113,"The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.",polyterpenoid catabolic process,biological_process
65509,GO:0016114,"The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.",terpenoid biosynthetic process,biological_process
65510,GO:0016115,"The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.",terpenoid catabolic process,biological_process
65511,GO:0016116,"The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.",carotenoid metabolic process,biological_process
65512,GO:0016117,"The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.",carotenoid biosynthetic process,biological_process
65513,GO:0016118,"The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.",carotenoid catabolic process,biological_process
65514,GO:0016119,"The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.",carotene metabolic process,biological_process
65515,GO:0016120,"The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.",carotene biosynthetic process,biological_process
65516,GO:0016121,"The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.",carotene catabolic process,biological_process
65517,GO:0016122,"The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.",xanthophyll metabolic process,biological_process
65518,GO:0016123,"The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.",xanthophyll biosynthetic process,biological_process
65519,GO:0016124,"The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.",xanthophyll catabolic process,biological_process
65520,GO:0016125,"The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",sterol metabolic process,biological_process
65521,GO:0016126,"The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",sterol biosynthetic process,biological_process
65522,GO:0016127,"The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",sterol catabolic process,biological_process
65523,GO:0016129,"The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.",phytosteroid biosynthetic process,biological_process
65524,GO:0016130,"The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.",phytosteroid catabolic process,biological_process
65525,GO:0016131,"The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.",brassinosteroid metabolic process,biological_process
65526,GO:0016132,"The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.",brassinosteroid biosynthetic process,biological_process
65527,GO:0016133,"The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.",brassinosteroid catabolic process,biological_process
65528,GO:0016134,"The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.",saponin metabolic process,biological_process
65529,GO:0016135,"The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.",saponin biosynthetic process,biological_process
65530,GO:0016136,"The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.",saponin catabolic process,biological_process
65531,GO:0016137,"The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.",glycoside metabolic process,biological_process
65532,GO:0016138,"The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.",glycoside biosynthetic process,biological_process
65533,GO:0016139,"The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.",glycoside catabolic process,biological_process
65534,GO:0016144,"The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.",S-glycoside biosynthetic process,biological_process
65535,GO:0016145,"The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.",S-glycoside catabolic process,biological_process
65536,GO:0016149,A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.,"translation release factor activity, codon specific",molecular_function
65537,GO:0016150,A translation release factor that is not specific to particular codons; binds to guanine nucleotides.,"translation release factor activity, codon nonspecific",molecular_function
65538,GO:0016151,Binding to a nickel (Ni) cation.,nickel cation binding,molecular_function
65539,GO:0016152,Catalysis of the reaction: H+ + Hg + NADP+ = Hg2+ + NADPH.,mercury (II) reductase (NADP+) activity,molecular_function
65540,GO:0016153,Catalysis of the reaction: 4-imidazolone-5-propanoate + H+ = trans-urocanate + H2O.,urocanate hydratase activity,molecular_function
65541,GO:0016154,Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.,pyrimidine-nucleoside phosphorylase activity,molecular_function
65542,GO:0016155,"Catalysis of the reaction: 10-formyltetrahydrofolate + H2O + NADP+ = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H+ + NADPH.",formyltetrahydrofolate dehydrogenase activity,molecular_function
65543,GO:0016156,Catalysis of the reaction: NAD+ + succinate = fumarate + H+ + NADH.,fumarate reductase (NADH) activity,molecular_function
65544,GO:0016157,Catalysis of the reaction: an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-diphosphate + H+ + sucrose. The phosphate acceptor can be UDP or ADP.,sucrose synthase activity,molecular_function
65545,GO:0016158,"Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.",inositol hexakisphosphate 3-phosphatase activity,molecular_function
65546,GO:0016159,"Catalysis of the reaction: (S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate.",muconolactone delta-isomerase activity,molecular_function
65547,GO:0016160,Catalysis of the hydrolysis of amylose or an amylose derivative.,amylase activity,molecular_function
65548,GO:0016161,"Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.",beta-amylase activity,molecular_function
65549,GO:0016162,"Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.","cellulose 1,4-beta-cellobiosidase activity",molecular_function
65550,GO:0016163,Catalysis of the reaction: 16 ATP + 16 H2O + N2 + 8 reduced [2Fe-2S]-[ferredoxin] = 16 ADP + 6 H+ + H2 + 2 NH4+ + 8 oxidized [2Fe-2S]-[ferredoxin] + 16 phosphate.,nitrogenase activity,molecular_function
65551,GO:0016165,"Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.",linoleate 13S-lipoxygenase activity,molecular_function
65552,GO:0016166,Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.,phytoene dehydrogenase activity,molecular_function
65553,GO:0016167,Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,glial cell-derived neurotrophic factor receptor activity,molecular_function
65554,GO:0016168,Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.,chlorophyll binding,molecular_function
65555,GO:0016169,"Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.",bacteriochlorophyll c binding,molecular_function
65556,GO:0016170,Binding to an interleukin-15 receptor.,interleukin-15 receptor binding,molecular_function
65557,GO:0016172,"Inhibits the growth and recrystallization of ice crystals, thereby lowering the freezing point of water and preventing cellular damage at subzero temperatures. This activity is observed in various cold-adapted organisms, including certain fish, insects, and plants, and contributes to survival in extreme cold environments by stabilizing supercooled liquid states.",antifreeze activity,molecular_function
65558,GO:0016174,Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + H2O2.,NAD(P)H oxidase H2O2-forming activity,molecular_function
65559,GO:0016175,Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.,superoxide-generating NAD(P)H oxidase activity,molecular_function
65560,GO:0016176,Binds to and increases the activity of the enzyme superoxide-generating NADPH oxidase.,superoxide-generating NADPH oxidase activator activity,molecular_function
65561,GO:0016180,"Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.",snRNA processing,biological_process
65562,GO:0016182,Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.,synaptic vesicle budding from endosome,biological_process
65563,GO:0016183,"The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.",synaptic vesicle coating,biological_process
65564,GO:0016185,"Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.",synaptic vesicle budding from presynaptic endocytic zone membrane,biological_process
65565,GO:0016188,Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.,synaptic vesicle maturation,biological_process
65566,GO:0016189,Fusion of a synaptic vesicle with an endosome.,synaptic vesicle to endosome fusion,biological_process
65567,GO:0016191,The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.,synaptic vesicle uncoating,biological_process
65568,GO:0016192,"A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.",vesicle-mediated transport,biological_process
65569,GO:0016197,"The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.",endosomal transport,biological_process
65570,GO:0016198,The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.,axon choice point recognition,biological_process
65571,GO:0016199,The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.,axon midline choice point recognition,biological_process
65572,GO:0016200,"The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.",synaptic target attraction,biological_process
65573,GO:0016201,The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.,synaptic target inhibition,biological_process
65574,GO:0016202,"Any process that modulates the frequency, rate or extent of striated muscle development.",regulation of striated muscle tissue development,biological_process
65575,GO:0016203,The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).,muscle attachment,biological_process
65576,GO:0016204,"The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.",determination of muscle attachment site,biological_process
65577,GO:0016205,Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.,selenocysteine methyltransferase activity,molecular_function
65578,GO:0016206,Catalysis of the reaction: a catechol + S-adenosyl-L-methionine = a guaiacol + H+ + S-adenosyl-L-homocysteine. Acts on catechols and on catecholamines such as adrenaline or noradrenaline.,catechol O-methyltransferase activity,molecular_function
65579,GO:0016207,Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.,4-coumarate-CoA ligase activity,molecular_function
65580,GO:0016208,"Binding to AMP, adenosine monophosphate.",AMP binding,molecular_function
65581,GO:0016209,"Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.",antioxidant activity,molecular_function
65582,GO:0016210,Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.,naringenin-chalcone synthase activity,molecular_function
65583,GO:0016211,"Catalysis of the ligation of ammonia (NH4+) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.",ammonia ligase activity,molecular_function
65584,GO:0016212,"Catalysis of the reaction: 2-oxoglutarate + L-kynurenine = H2O + kynurenate + L-glutamate. The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into kynurenate by a spontaneous reaction. Also acts on 3-hydroxykynurenine to form xanthurenate.",L-kynurenine:2-oxoglutarate transaminase activity,molecular_function
65585,GO:0016213,"Catalysis of the introduction of a cis double bond at carbon 6 of acyl-CoAs, introducing a new double bond between a pre-existing double bond and the carboxyl-end of the fatty acid. Specific reactions include: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O; and (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H+ = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] +...",acyl-CoA 6-desaturase activity,molecular_function
65586,GO:0016215,Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.,acyl-CoA desaturase activity,molecular_function
65587,GO:0016216,Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = 2 H2O + isopenicillin N.,isopenicillin-N synthase activity,molecular_function
65588,GO:0016218,"Catalysis of a multistep reaction that produce polyketides through decarboxylative condensation of carboxylic acids. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condens...",polyketide synthase activity,molecular_function
65589,GO:0016222,"A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.",procollagen-proline 4-dioxygenase complex,cellular_component
65590,GO:0016223,Catalysis of the reaction: L-alanine + 3-oxopropanoate = beta-alanine + pyruvate.,beta-alanine:pyruvate transaminase activity,molecular_function
65591,GO:0016226,The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.,iron-sulfur cluster assembly,biological_process
65592,GO:0016229,Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.,steroid dehydrogenase activity,molecular_function
65593,GO:0016230,Binds to and increases the activity of the enzyme sphingomyelin phosphodiesterase.,sphingomyelin phosphodiesterase activator activity,molecular_function
65594,GO:0016231,Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.,beta-N-acetylglucosaminidase activity,molecular_function
65595,GO:0016232,"Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).",HNK-1 sulfotransferase activity,molecular_function
65596,GO:0016233,"A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.",telomere capping,biological_process
65597,GO:0016234,A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.,inclusion body,cellular_component
65598,GO:0016235,An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.,aggresome,cellular_component
65599,GO:0016236,The autophagic process that proceeds via the formation of an autophagosome.,macroautophagy,biological_process
65600,GO:0016237,"A type of autophagy where cytosolic components are ingested by late endosomes, lysosomes or yeast-type lytic vacuoles by direct invagination of the compartment membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane.",microautophagy,biological_process
65601,GO:0016239,"Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.",positive regulation of macroautophagy,biological_process
65602,GO:0016240,"The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.",autophagosome membrane docking,biological_process
65603,GO:0016241,"Any process that modulates the frequency, rate or extent of macroautophagy.",regulation of macroautophagy,biological_process
65604,GO:0016242,"Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.",negative regulation of macroautophagy,biological_process
65605,GO:0016243,Any process that modulates the size of the autophagosome.,regulation of autophagosome size,biological_process
65606,GO:0016247,"Binds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.",channel regulator activity,molecular_function
65607,GO:0016248,"Binds to and stops, prevents, or reduces the activity of a channel.",channel inhibitor activity,molecular_function
65608,GO:0016250,Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.,N-sulfoglucosamine sulfohydrolase activity,molecular_function
65609,GO:0016251,"A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and ...",RNA polymerase II general transcription initiation factor activity,molecular_function
65610,GO:0016255,A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.,attachment of GPI anchor to protein,biological_process
65611,GO:0016256,The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.,N-glycan processing to lysosome,biological_process
65612,GO:0016258,"The generation, in the Golgi apparatus, of side chain diversity from paucimannose mannose Man5GlcNAc2-Asn or Man3GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.",Golgi apparatus N-glycan diversification,biological_process
65613,GO:0016260,"The chemical reactions and pathways resulting in the formation of L-selenocysteine, an essential component of glutathione peroxidase and some other proteins.",L-selenocysteine biosynthetic process,biological_process
65614,GO:0016261,"The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.",L-selenocysteine catabolic process,biological_process
65615,GO:0016262,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.,protein N-acetylglucosaminyltransferase activity,molecular_function
65616,GO:0016263,Catalysis of the reaction: an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H+.,"N-acetylgalactosaminide beta-1,3-galactosyltransferase activity",molecular_function
65617,GO:0016264,"Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.",gap junction assembly,biological_process
65618,GO:0016266,"A glycoprotein biosynthetic process starting with the covalent linkage of an N-acetyl-galactosamine via an alpha-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation via N-acetylgalactosamine,biological_process
65619,GO:0016272,"A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.",prefoldin complex,cellular_component
65620,GO:0016273,Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.,arginine N-methyltransferase activity,molecular_function
65621,GO:0016274,Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.,protein-arginine N-methyltransferase activity,molecular_function
65622,GO:0016278,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.,lysine N-methyltransferase activity,molecular_function
65623,GO:0016279,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.,protein-lysine N-methyltransferase activity,molecular_function
65624,GO:0016281,"The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.",eukaryotic translation initiation factor 4F complex,cellular_component
65625,GO:0016282,"A protein complex composed of the 40S ribosomal subunit plus eIF1, eIF1A, eIF3, eIF5, and eIF2-GTP-bound methionyl-initiator methionine tRNA.",eukaryotic 43S preinitiation complex,cellular_component
65626,GO:0016285,"Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.",alanyl aminopeptidase activity,molecular_function
65627,GO:0016286,Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channe...,small conductance calcium-activated potassium channel activity,molecular_function
65628,GO:0016287,Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.,glycerone-phosphate O-acyltransferase activity,molecular_function
65629,GO:0016289,Catalysis of the reaction: an acyl-CoA + H2O = a carboxylate + CoA + H+.,acyl-CoA hydrolase activity,molecular_function
65630,GO:0016297,Catalysis of the reaction: a fatty acyl-[ACP] + H2O = a fatty acid + H+ + holo-[acyl-carrier protein].,fatty acyl-[ACP] hydrolase activity,molecular_function
65631,GO:0016298,Catalysis of the hydrolysis of a lipid.,lipase activity,molecular_function
65632,GO:0016300,Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.,tRNA (uridine) methyltransferase activity,molecular_function
65633,GO:0016301,"Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",kinase activity,molecular_function
65634,GO:0016303,Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+.,1-phosphatidylinositol-3-kinase activity,molecular_function
65635,GO:0016308,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+.",1-phosphatidylinositol-4-phosphate 5-kinase activity,molecular_function
65636,GO:0016309,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+.",1-phosphatidylinositol-5-phosphate 4-kinase activity,molecular_function
65637,GO:0016310,"The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.",phosphorylation,biological_process
65638,GO:0016311,The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.,dephosphorylation,biological_process
65639,GO:0016312,Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.,inositol bisphosphate phosphatase activity,molecular_function
65640,GO:0016314,"Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.","phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity",molecular_function
65641,GO:0016316,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.","phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity",molecular_function
65642,GO:0016318,The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.,ommatidial rotation,biological_process
65643,GO:0016319,"The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.",mushroom body development,biological_process
65644,GO:0016320,The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.,endoplasmic reticulum membrane fusion,biological_process
65645,GO:0016321,"The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.",female meiosis chromosome segregation,biological_process
65646,GO:0016322,The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.,neuron remodeling,biological_process
65647,GO:0016323,"The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.",basolateral plasma membrane,cellular_component
65648,GO:0016324,The region of the plasma membrane located at the apical end of the cell.,apical plasma membrane,cellular_component
65649,GO:0016325,Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.,oocyte microtubule cytoskeleton organization,biological_process
65650,GO:0016327,The apical end of the lateral plasma membrane of epithelial cells.,apicolateral plasma membrane,cellular_component
65651,GO:0016328,"The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.",lateral plasma membrane,cellular_component
65652,GO:0016330,A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.,second mitotic wave involved in compound eye morphogenesis,biological_process
65653,GO:0016331,The process in which the anatomical structures of embryonic epithelia are generated and organized.,morphogenesis of embryonic epithelium,biological_process
65654,GO:0016332,"Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.",establishment or maintenance of polarity of embryonic epithelium,biological_process
65655,GO:0016333,The process in which the anatomical structures of a follicular epithelium are generated and organized.,morphogenesis of follicular epithelium,biological_process
65656,GO:0016334,"Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.",establishment or maintenance of polarity of follicular epithelium,biological_process
65657,GO:0016335,The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.,morphogenesis of larval imaginal disc epithelium,biological_process
65658,GO:0016336,"Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.",establishment or maintenance of polarity of larval imaginal disc epithelium,biological_process
65659,GO:0016338,The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.,calcium-independent cell-cell adhesion,biological_process
65660,GO:0016339,The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.,calcium-dependent cell-cell adhesion,biological_process
65661,GO:0016340,The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.,calcium-dependent cell-matrix adhesion,biological_process
65662,GO:0016342,"Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.",catenin complex,cellular_component
65663,GO:0016344,"The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.",meiotic chromosome movement towards spindle pole,biological_process
65664,GO:0016345,"The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.",female meiotic chromosome movement towards spindle pole,biological_process
65665,GO:0016346,"The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.",male meiotic chromosome movement towards spindle pole,biological_process
65666,GO:0016348,The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.,imaginal disc-derived leg joint morphogenesis,biological_process
65667,GO:0016358,"The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.",dendrite development,biological_process
65668,GO:0016360,"The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.",sensory organ precursor cell fate determination,biological_process
65669,GO:0016361,"Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.","activin receptor activity, type I",molecular_function
65670,GO:0016362,"Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.","activin receptor activity, type II",molecular_function
65671,GO:0016363,"A dynamic, proteinaceous framework within the nucleus of eukaryotic cells, composed of proteins and RNA, that provides structural support for chromatin organization, gene regulation, and nuclear processes.",nuclear matrix,cellular_component
65672,GO:0016402,Catalysis of the reaction: (2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2.,pristanoyl-CoA oxidase activity,molecular_function
65673,GO:0016403,"Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.",dimethylargininase activity,molecular_function
65674,GO:0016404,"Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.",15-hydroxyprostaglandin dehydrogenase (NAD+) activity,molecular_function
65675,GO:0016405,Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.,CoA-ligase activity,molecular_function
65676,GO:0016406,Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.,carnitine O-acyltransferase activity,molecular_function
65677,GO:0016407,Catalysis of the transfer of an acetyl group to an acceptor molecule.,acetyltransferase activity,molecular_function
65678,GO:0016409,Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.,palmitoyltransferase activity,molecular_function
65679,GO:0016411,Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.,acylglycerol O-acyltransferase activity,molecular_function
65680,GO:0016412,Catalysis of the reaction: a fatty acyl-CoA + L-seryl-[protein] = CoA + O-fatty acyl-L-seryl-[protein].,serine O-acyltransferase activity,molecular_function
65681,GO:0016413,Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.,O-acetyltransferase activity,molecular_function
65682,GO:0016414,Catalysis of the reaction: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + octanoyl-CoA = (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + CoA.,diglucosylglycerate octanoyltransferase activity,molecular_function
65683,GO:0016416,Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.,O-palmitoyltransferase activity,molecular_function
65684,GO:0016418,Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.,S-acetyltransferase activity,molecular_function
65685,GO:0016419,Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.,S-malonyltransferase activity,molecular_function
65686,GO:0016420,Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.,malonyltransferase activity,molecular_function
65687,GO:0016421,"Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",CoA carboxylase activity,molecular_function
65688,GO:0016422,Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.,mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,molecular_function
65689,GO:0016423,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine in tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.,tRNA (guanine) methyltransferase activity,molecular_function
65690,GO:0016426,Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.,tRNA (adenine) methyltransferase activity,molecular_function
65691,GO:0016427,Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.,tRNA (cytidine) methyltransferase activity,molecular_function
65692,GO:0016428,"Catalysis of the reaction: a cytidine in tRNA + S-adenosyl-L-methionine = a 5-methylcytidine in tRNA + S-adenosyl-L-homocysteine + H+. This modification can occur on several residues, including cytidine(34), cytidine(40), cytidine(48), and cytidine(49).",tRNA (cytidine-N5)-methyltransferase activity,molecular_function
65693,GO:0016432,Catalysis of the reaction: a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H+.,tRNA-uridine aminocarboxypropyltransferase activity,molecular_function
65694,GO:0016433,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.,rRNA (adenine) methyltransferase activity,molecular_function
65695,GO:0016434,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.,rRNA (cytosine) methyltransferase activity,molecular_function
65696,GO:0016435,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.,rRNA (guanine) methyltransferase activity,molecular_function
65697,GO:0016436,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.,rRNA (uridine) methyltransferase activity,molecular_function
65698,GO:0016438,Catalysis of the reaction: GDP-alpha-D-mannose + queuosine34 in tRNA(Asp) = GDP + H+ + O-4''-alpha-D-mannosylqueuosine34 in tRNA(Asp).,tRNA-queuosine(34) beta-mannosyltransferase activity,molecular_function
65699,GO:0016441,The inactivation of gene expression that occurs after transcription.,post-transcriptional gene silencing,biological_process
65700,GO:0016442,"A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.",RISC complex,cellular_component
65701,GO:0016444,Recombination occurring within or between DNA molecules in somatic cells.,somatic cell DNA recombination,biological_process
65702,GO:0016445,The somatic process that results in the generation of sequence diversity of immunoglobulins.,somatic diversification of immunoglobulins,biological_process
65703,GO:0016446,Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.,somatic hypermutation of immunoglobulin genes,biological_process
65704,GO:0016447,"The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.",somatic recombination of immunoglobulin gene segments,biological_process
65705,GO:0016453,Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.,C-acetyltransferase activity,molecular_function
65706,GO:0016454,Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.,C-palmitoyltransferase activity,molecular_function
65707,GO:0016456,An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.,"X chromosome located dosage compensation complex, transcription activating",cellular_component
65708,GO:0016459,"A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.",myosin complex,cellular_component
65709,GO:0016460,"A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.",myosin II complex,cellular_component
65710,GO:0016461,A portmanteau term for myosins other than myosin II.,unconventional myosin complex,cellular_component
65711,GO:0016462,Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.,pyrophosphatase activity,molecular_function
65712,GO:0016463,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) = ADP + phosphate + Zn2+(out).,P-type zinc transporter activity,molecular_function
65713,GO:0016464,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.,chloroplast protein-transporting ATPase activity,molecular_function
65714,GO:0016465,"Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.",chaperonin ATPase complex,cellular_component
65715,GO:0016469,"A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ...",proton-transporting two-sector ATPase complex,cellular_component
65716,GO:0016471,"A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.",vacuolar proton-transporting V-type ATPase complex,cellular_component
65717,GO:0016472,"A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.",sodium ion-transporting two-sector ATPase complex,cellular_component
65718,GO:0016473,A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.,sodium ion-transporting F-type ATPase complex,cellular_component
65719,GO:0016474,A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.,sodium ion-transporting V-type ATPase complex,cellular_component
65720,GO:0016475,The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.,detection of nuclear:cytoplasmic ratio,biological_process
65721,GO:0016476,Any process that modulates the surface configuration of an embryonic cell.,regulation of embryonic cell shape,biological_process
65722,GO:0016477,The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.,cell migration,biological_process
65723,GO:0016479,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.",negative regulation of transcription by RNA polymerase I,biological_process
65724,GO:0016480,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.",negative regulation of transcription by RNA polymerase III,biological_process
65725,GO:0016482,The directed movement of substances or organelles within the cytosol.,cytosolic transport,biological_process
65726,GO:0016483,Increases the activity of the enzyme tryptophase hydroxylase.,tryptophan hydroxylase activator activity,molecular_function
65727,GO:0016485,Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.,protein processing,biological_process
65728,GO:0016486,The generation of a mature peptide hormone by posttranslational processing of a prohormone.,peptide hormone processing,biological_process
65729,GO:0016487,"The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.",farnesol metabolic process,biological_process
65730,GO:0016488,"The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.",farnesol catabolic process,biological_process
65731,GO:0016490,"The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.",structural constituent of peritrophic membrane,molecular_function
65732,GO:0016491,"Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.",oxidoreductase activity,molecular_function
65733,GO:0016492,Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.,G protein-coupled neurotensin receptor activity,molecular_function
65734,GO:0016493,Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.,C-C chemokine receptor activity,molecular_function
65735,GO:0016494,Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.,C-X-C chemokine receptor activity,molecular_function
65736,GO:0016495,Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.,C-X3-C chemokine receptor activity,molecular_function
65737,GO:0016496,"Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.",substance P receptor activity,molecular_function
65738,GO:0016497,"Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.",substance K receptor activity,molecular_function
65739,GO:0016498,"Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.",neuromedin K receptor activity,molecular_function
65740,GO:0016499,Combining with orexin to initiate a change in cell activity.,orexin receptor activity,molecular_function
65741,GO:0016500,Combining with a protein hormone to initiate a change in cell activity.,protein-hormone receptor activity,molecular_function
65742,GO:0016501,Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.,prostacyclin receptor activity,molecular_function
65743,GO:0016502,Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.,nucleotide receptor activity,molecular_function
65744,GO:0016503,Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.,pheromone receptor activity,molecular_function
65745,GO:0016504,Binds to and increases the activity of a peptidase.,peptidase activator activity,molecular_function
65746,GO:0016505,Binds to and increases the activity of a peptidase that is involved in the apoptotic process.,peptidase activator activity involved in apoptotic process,molecular_function
65747,GO:0016507,"A multienzyme complex possessing three activities in two subunits (alpha and beta) that catalyzes three steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix. The alpha subunit comprises the enoyl-CoA hydratase (ECH) and 3-hydroxyacyl-CoA dehydrogenase (HACD) activities, and the beta subunit contains the acetyl-CoA C-acyltransferase (KACT)/thiolase activity.",mitochondrial fatty acid beta-oxidation multienzyme complex,cellular_component
65748,GO:0016509,Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity,molecular_function
65749,GO:0016513,"A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.",core-binding factor complex,cellular_component
65750,GO:0016514,"A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.",SWI/SNF complex,cellular_component
65751,GO:0016515,Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-13 receptor activity,molecular_function
65752,GO:0016516,A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.,interleukin-4 receptor complex,cellular_component
65753,GO:0016517,Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-12 receptor activity,molecular_function
65754,GO:0016519,Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.,gastric inhibitory peptide receptor activity,molecular_function
65755,GO:0016520,Combining with growth hormone-releasing hormone to initiate a change in cell activity.,growth hormone-releasing hormone receptor activity,molecular_function
65756,GO:0016521,"The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.",pituitary adenylate cyclase activating polypeptide activity,molecular_function
65757,GO:0016524,"Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",latrotoxin receptor activity,molecular_function
65758,GO:0016525,"Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.",negative regulation of angiogenesis,biological_process
65759,GO:0016528,The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.,sarcoplasm,cellular_component
65760,GO:0016529,"A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.",sarcoplasmic reticulum,cellular_component
65761,GO:0016530,Binding to and delivering metal ions to a target protein.,metallochaperone activity,molecular_function
65762,GO:0016531,Directly binding to and delivering copper ions to a target protein.,copper chaperone activity,molecular_function
65763,GO:0016532,"A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.",superoxide dismutase copper chaperone activity,molecular_function
65764,GO:0016533,"A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent.",protein kinase 5 complex,cellular_component
65765,GO:0016538,"Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.",cyclin-dependent protein serine/threonine kinase regulator activity,molecular_function
65766,GO:0016539,The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.,intein-mediated protein splicing,biological_process
65767,GO:0016540,Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.,protein autoprocessing,biological_process
65768,GO:0016543,"The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.","male courtship behavior, orientation prior to leg tapping and wing vibration",biological_process
65769,GO:0016544,The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.,"male courtship behavior, tapping to detect pheromone",biological_process
65770,GO:0016545,The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.,"male courtship behavior, veined wing vibration",biological_process
65771,GO:0016546,The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.,"male courtship behavior, proboscis-mediated licking",biological_process
65772,GO:0016553,Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).,base conversion or substitution editing,biological_process
65773,GO:0016554,The conversion of a cytosine residue to uridine in an RNA molecule by deamination.,cytidine to uridine editing,biological_process
65774,GO:0016555,The conversion of a uridine residue to cytosine in an RNA molecule by amination.,uridine to cytidine editing,biological_process
65775,GO:0016556,The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.,mRNA modification,biological_process
65776,GO:0016557,"The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.",peroxisome membrane biogenesis,biological_process
65777,GO:0016558,"The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.",protein import into peroxisome matrix,biological_process
65778,GO:0016559,The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.,peroxisome fission,biological_process
65779,GO:0016560,The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.,"protein import into peroxisome matrix, docking",biological_process
65780,GO:0016561,The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.,"protein import into peroxisome matrix, translocation",biological_process
65781,GO:0016562,The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.,"protein import into peroxisome matrix, receptor recycling",biological_process
65782,GO:0016567,The process in which one or more ubiquitin groups are added to a protein.,protein ubiquitination,biological_process
65783,GO:0016579,The removal of one or more ubiquitin groups from a protein.,protein deubiquitination,biological_process
65784,GO:0016581,"An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.",NuRD complex,cellular_component
65785,GO:0016586,"A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.",RSC-type complex,cellular_component
65786,GO:0016587,A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.,Isw1 complex,cellular_component
65787,GO:0016589,"An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.",NURF complex,cellular_component
65788,GO:0016590,"An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.",ACF complex,cellular_component
65789,GO:0016591,"A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.","RNA polymerase II, holoenzyme",cellular_component
65790,GO:0016592,"A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -...",mediator complex,cellular_component
65791,GO:0016593,"A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.",Cdc73/Paf1 complex,cellular_component
65792,GO:0016594,"Binding to glycine, aminoethanoic acid.",glycine binding,molecular_function
65793,GO:0016595,"Binding to glutamate, the anion of 2-aminopentanedioic acid.",glutamate binding,molecular_function
65794,GO:0016596,Binding to thienylcyclohexylpiperidine.,thienylcyclohexylpiperidine binding,molecular_function
65795,GO:0016597,"Binding to an amino acid, organic acids containing one or more amino substituents.",amino acid binding,molecular_function
65796,GO:0016598,The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.,protein arginylation,biological_process
65797,GO:0016600,"A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.",flotillin complex,cellular_component
65798,GO:0016601,An intracellular signaling cassette in which a small monomeric GTPase of the Rac subfamily relays a signal.,Rac protein signal transduction,biological_process
65799,GO:0016602,"A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.",CCAAT-binding factor complex,cellular_component
65800,GO:0016603,Catalysis of the reaction: N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4+.,glutaminyl-peptide cyclotransferase activity,molecular_function
65801,GO:0016604,Membraneless organelle present in the nucleoplasm and usually visible by confocal microscopy.,nuclear body,cellular_component
65802,GO:0016605,"A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.",PML body,cellular_component
65803,GO:0016606,"A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.",LYSP100-associated nuclear domain,cellular_component
65804,GO:0016607,"A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.",nuclear speck,cellular_component
65805,GO:0016608,"The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.",growth hormone-releasing hormone activity,molecular_function
65806,GO:0016610,"An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.",nitrogenase complex,cellular_component
65807,GO:0016611,"An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.",iron-iron nitrogenase complex,cellular_component
65808,GO:0016612,"An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.",molybdenum-iron nitrogenase complex,cellular_component
65809,GO:0016613,"An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.",vanadium-iron nitrogenase complex,cellular_component
65810,GO:0016614,Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on CH-OH group of donors",molecular_function
65811,GO:0016615,Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.,malate dehydrogenase activity,molecular_function
65812,GO:0016616,Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.,"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",molecular_function
65813,GO:0016617,Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.,4-oxoproline reductase activity,molecular_function
65814,GO:0016618,Catalysis of the reaction: (R)-glycerate + NAD(P)+ = 3-hydroxypyruvate + NAD(P)H + H+.,hydroxypyruvate reductase [NAD(P)H] activity,molecular_function
65815,GO:0016620,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",molecular_function
65816,GO:0016621,Catalysis of the reaction: (E)-cinnamaldehyde + NADP+ + CoA = (E)-cinnamoyl-CoA + NADPH + H+.,cinnamoyl-CoA reductase (NADP+) activity,molecular_function
65817,GO:0016622,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor",molecular_function
65818,GO:0016623,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor",molecular_function
65819,GO:0016624,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor",molecular_function
65820,GO:0016625,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor",molecular_function
65821,GO:0016627,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on the CH-CH group of donors",molecular_function
65822,GO:0016628,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor",molecular_function
65823,GO:0016629,"Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + H+ + NADPH.",12-oxophytodienoate reductase activity,molecular_function
65824,GO:0016630,Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.,protochlorophyllide reductase activity,molecular_function
65825,GO:0016631,"Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.",enoyl-[acyl-carrier-protein] reductase [NAD(P)H] activity,molecular_function
65826,GO:0016632,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.,"oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor",molecular_function
65827,GO:0016633,"Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.",galactonolactone dehydrogenase activity,molecular_function
65828,GO:0016634,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.,"oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor",molecular_function
65829,GO:0016635,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.,"oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor",molecular_function
65830,GO:0016636,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor",molecular_function
65831,GO:0016638,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on the CH-NH2 group of donors",molecular_function
65832,GO:0016639,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.,"oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor",molecular_function
65833,GO:0016640,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.,"oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor",molecular_function
65834,GO:0016641,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.,"oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor",molecular_function
65835,GO:0016642,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.,"oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor",molecular_function
65836,GO:0016643,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor",molecular_function
65837,GO:0016645,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on the CH-NH group of donors",molecular_function
65838,GO:0016646,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor",molecular_function
65839,GO:0016647,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.,"oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor",molecular_function
65840,GO:0016648,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.,"oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor",molecular_function
65841,GO:0016649,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.,"oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor",molecular_function
65842,GO:0016651,Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on NAD(P)H",molecular_function
65843,GO:0016652,Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.,"oxidoreductase activity, acting on NAD(P)H as acceptor",molecular_function
65844,GO:0016653,Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.,"oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor",molecular_function
65845,GO:0016655,Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.,"oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor",molecular_function
65846,GO:0016656,Catalysis of the reaction: 2 monodehydro-L-ascorbate radical + NADH + H+ = 2 L-ascorbate + NAD+.,monodehydroascorbate reductase (NADH) activity,molecular_function
65847,GO:0016661,"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.","oxidoreductase activity, acting on other nitrogenous compounds as donors",molecular_function
65848,GO:0016662,"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.","oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor",molecular_function
65849,GO:0016663,"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.","oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor",molecular_function
65850,GO:0016664,"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.","oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor",molecular_function
65851,GO:0016667,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on a sulfur group of donors",molecular_function
65852,GO:0016668,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor",molecular_function
65853,GO:0016669,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.,"oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor",molecular_function
65854,GO:0016670,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.,"oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor",molecular_function
65855,GO:0016671,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.,"oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor",molecular_function
65856,GO:0016672,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.,"oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor",molecular_function
65857,GO:0016673,Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor",molecular_function
65858,GO:0016675,Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on a heme group of donors",molecular_function
65859,GO:0016677,Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.,"oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor",molecular_function
65860,GO:0016679,Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on diphenols and related substances as donors",molecular_function
65861,GO:0016680,"Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.","oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor",molecular_function
65862,GO:0016682,"Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.","oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor",molecular_function
65863,GO:0016684,Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.,"oxidoreductase activity, acting on peroxide as acceptor",molecular_function
65864,GO:0016688,Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O.,L-ascorbate peroxidase activity,molecular_function
65865,GO:0016689,Catalysis of the reaction: 2 Mn2+ + 2 H+ + H2O2 = 2 Mn3+ + 2 H2O.,manganese peroxidase activity,molecular_function
65866,GO:0016690,"Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.",diarylpropane peroxidase activity,molecular_function
65867,GO:0016691,Catalysis of the reaction: 2 R-H + 2 chloride + H2O2 = 2 R-Cl + 2 H2O.,chloride peroxidase activity,molecular_function
65868,GO:0016692,Catalysis of the reaction: H2O2 + NADH + H+ = 2 H2O + NAD+.,NADH peroxidase activity,molecular_function
65869,GO:0016695,Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.,"oxidoreductase activity, acting on hydrogen as donor",molecular_function
65870,GO:0016696,Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor",molecular_function
65871,GO:0016697,Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.,"oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor",molecular_function
65872,GO:0016699,Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor",molecular_function
65873,GO:0016701,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen",molecular_function
65874,GO:0016702,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",molecular_function
65875,GO:0016703,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.","oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)",molecular_function
65876,GO:0016705,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",molecular_function
65877,GO:0016706,"Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.",2-oxoglutarate-dependent dioxygenase activity,molecular_function
65878,GO:0016707,Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.,gibberellin 3-beta-dioxygenase activity,molecular_function
65879,GO:0016708,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor",molecular_function
65880,GO:0016709,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",molecular_function
65881,GO:0016710,Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.,trans-cinnamate 4-monooxygenase activity,molecular_function
65882,GO:0016711,Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.,flavonoid 3'-monooxygenase activity,molecular_function
65883,GO:0016712,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",molecular_function
65884,GO:0016713,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen",molecular_function
65885,GO:0016714,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen",molecular_function
65886,GO:0016715,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen",molecular_function
65887,GO:0016716,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen",molecular_function
65888,GO:0016717,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.","oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water",molecular_function
65889,GO:0016719,"Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-lycopene + 2 a quinol.","9,9'-di-cis-zeta-carotene desaturase activity",molecular_function
65890,GO:0016720,"Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-lipid Delta(12)-acetylenase activity,molecular_function
65891,GO:0016721,Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.,"oxidoreductase activity, acting on superoxide radicals as acceptor",molecular_function
65892,GO:0016722,Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.,"oxidoreductase activity, acting on metal ions",molecular_function
65893,GO:0016723,Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.,"oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor",molecular_function
65894,GO:0016724,Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.,"oxidoreductase activity, acting on metal ions, oxygen as acceptor",molecular_function
65895,GO:0016725,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on CH or CH2 groups",molecular_function
65896,GO:0016726,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.,"oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor",molecular_function
65897,GO:0016727,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.,"oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor",molecular_function
65898,GO:0016728,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.,"oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor",molecular_function
65899,GO:0016730,Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on iron-sulfur proteins as donors",molecular_function
65900,GO:0016731,Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.,"oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor",molecular_function
65901,GO:0016732,Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.,"oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor",molecular_function
65902,GO:0016737,Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on reduced flavodoxin as donor",molecular_function
65903,GO:0016738,Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.,"oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor",molecular_function
65904,GO:0016740,"Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.",transferase activity,molecular_function
65905,GO:0016741,Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).,"transferase activity, transferring one-carbon groups",molecular_function
65906,GO:0016742,Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).,"hydroxymethyl-, formyl- and related transferase activity",molecular_function
65907,GO:0016743,Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).,carboxyl- or carbamoyltransferase activity,molecular_function
65908,GO:0016744,Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).,transketolase or transaldolase activity,molecular_function
65909,GO:0016746,Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).,acyltransferase activity,molecular_function
65910,GO:0016747,"Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).","acyltransferase activity, transferring groups other than amino-acyl groups",molecular_function
65911,GO:0016748,Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.,succinyltransferase activity,molecular_function
65912,GO:0016749,Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.,N-succinyltransferase activity,molecular_function
65913,GO:0016750,Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.,O-succinyltransferase activity,molecular_function
65914,GO:0016751,Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.,S-succinyltransferase activity,molecular_function
65915,GO:0016752,Catalysis of the transfer of a sinapoyl group to an acceptor molecule.,sinapoyltransferase activity,molecular_function
65916,GO:0016753,Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.,O-sinapoyltransferase activity,molecular_function
65917,GO:0016754,Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.,sinapoylglucose-malate O-sinapoyltransferase activity,molecular_function
65918,GO:0016755,Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).,aminoacyltransferase activity,molecular_function
65919,GO:0016756,Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.,glutathione gamma-glutamylcysteinyltransferase activity,molecular_function
65920,GO:0016757,Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).,glycosyltransferase activity,molecular_function
65921,GO:0016758,Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).,hexosyltransferase activity,molecular_function
65922,GO:0016759,"Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).",cellulose synthase activity,molecular_function
65923,GO:0016760,"Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).",cellulose synthase (UDP-forming) activity,molecular_function
65924,GO:0016761,"Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).",cellulose synthase (GDP-forming) activity,molecular_function
65925,GO:0016762,"Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.",xyloglucan:xyloglucosyl transferase activity,molecular_function
65926,GO:0016763,Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).,pentosyltransferase activity,molecular_function
65927,GO:0016765,Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).,"transferase activity, transferring alkyl or aryl (other than methyl) groups",molecular_function
65928,GO:0016768,Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.,spermine synthase activity,molecular_function
65929,GO:0016769,Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).,"transferase activity, transferring nitrogenous groups",molecular_function
65930,GO:0016772,Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).,"transferase activity, transferring phosphorus-containing groups",molecular_function
65931,GO:0016773,Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).,"phosphotransferase activity, alcohol group as acceptor",molecular_function
65932,GO:0016774,Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).,"phosphotransferase activity, carboxyl group as acceptor",molecular_function
65933,GO:0016775,Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).,"phosphotransferase activity, nitrogenous group as acceptor",molecular_function
65934,GO:0016776,Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).,"phosphotransferase activity, phosphate group as acceptor",molecular_function
65935,GO:0016778,Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).,diphosphotransferase activity,molecular_function
65936,GO:0016779,Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).,nucleotidyltransferase activity,molecular_function
65937,GO:0016780,"Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).","phosphotransferase activity, for other substituted phosphate groups",molecular_function
65938,GO:0016781,"Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.","phosphotransferase activity, paired acceptors",molecular_function
65939,GO:0016782,Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).,"transferase activity, transferring sulphur-containing groups",molecular_function
65940,GO:0016783,Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).,sulfurtransferase activity,molecular_function
65941,GO:0016784,Catalysis of the reaction: 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H+. Note that 2-oxo-3-sulfanylpropanoate is also known as 3-mercaptopyruvate.,3-mercaptopyruvate sulfurtransferase activity,molecular_function
65942,GO:0016785,Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).,selenotransferase activity,molecular_function
65943,GO:0016787,"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.",hydrolase activity,molecular_function
65944,GO:0016788,Catalysis of the hydrolysis of any ester bond.,"hydrolase activity, acting on ester bonds",molecular_function
65945,GO:0016790,"Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.",thiolester hydrolase activity,molecular_function
65946,GO:0016791,"Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.",phosphatase activity,molecular_function
65947,GO:0016793,Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.,triphosphoric monoester hydrolase activity,molecular_function
65948,GO:0016794,"Catalysis of the hydrolysis of a diphosphoester, releasing a diphosphate and a free hydroxyl group.",diphosphoric monoester hydrolase activity,molecular_function
65949,GO:0016795,Catalysis of the hydrolysis of a phosphoric triester.,phosphoric triester hydrolase activity,molecular_function
65950,GO:0016798,Catalysis of the hydrolysis of any glycosyl bond.,"hydrolase activity, acting on glycosyl bonds",molecular_function
65951,GO:0016799,Catalysis of the hydrolysis of any N-glycosyl bond.,"hydrolase activity, hydrolyzing N-glycosyl compounds",molecular_function
65952,GO:0016801,"Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.","hydrolase activity, acting on ether bonds",molecular_function
65953,GO:0016802,"Catalysis of the hydrolysis of a thioether bond, -S-.",trialkylsulfonium hydrolase activity,molecular_function
65954,GO:0016803,"Catalysis of the hydrolysis of an ether bond, -O-.",ether hydrolase activity,molecular_function
65955,GO:0016805,Catalysis of the hydrolysis of a dipeptide.,dipeptidase activity,molecular_function
65956,GO:0016807,Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.,cysteine-type carboxypeptidase activity,molecular_function
65957,GO:0016810,"Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",molecular_function
65958,GO:0016811,Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.,"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides",molecular_function
65959,GO:0016812,Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.,"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides",molecular_function
65960,GO:0016813,"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines",molecular_function
65961,GO:0016814,"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines",molecular_function
65962,GO:0016815,"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles",molecular_function
65963,GO:0016817,Catalysis of the hydrolysis of any acid anhydride.,"hydrolase activity, acting on acid anhydrides",molecular_function
65964,GO:0016818,Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.,"hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides",molecular_function
65965,GO:0016819,"Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.","hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides",molecular_function
65966,GO:0016822,Catalysis of the hydrolysis of any carbon-carbon bond.,"hydrolase activity, acting on carbon-carbon bonds",molecular_function
65967,GO:0016823,"Catalysis of the hydrolysis of any carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.","hydrolase activity, acting on carbon-carbon bonds, in ketonic substances",molecular_function
65968,GO:0016824,Catalysis of the hydrolysis of any halide bond.,"hydrolase activity, acting on halide bonds",molecular_function
65969,GO:0016825,Catalysis of the hydrolysis of any phosphorus-nitrogen bond.,"hydrolase activity, acting on phosphorus-nitrogen bonds",molecular_function
65970,GO:0016826,Catalysis of the hydrolysis of any sulfur-nitrogen bond.,"hydrolase activity, acting on sulfur-nitrogen bonds",molecular_function
65971,GO:0016827,Catalysis of the hydrolysis of any carbon-phosphorus bond.,"hydrolase activity, acting on carbon-phosphorus bonds",molecular_function
65972,GO:0016828,Catalysis of the hydrolysis of any sulfur-sulfur bond.,"hydrolase activity, acting on sulfur-sulfur bonds",molecular_function
65973,GO:0016829,"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.",lyase activity,molecular_function
65974,GO:0016830,"Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.",carbon-carbon lyase activity,molecular_function
65975,GO:0016831,Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.,carboxy-lyase activity,molecular_function
65976,GO:0016832,"Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.",aldehyde-lyase activity,molecular_function
65977,GO:0016833,"Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.",oxo-acid-lyase activity,molecular_function
65978,GO:0016835,Catalysis of the breakage of a carbon-oxygen bond.,carbon-oxygen lyase activity,molecular_function
65979,GO:0016836,Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.,hydro-lyase activity,molecular_function
65980,GO:0016837,Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.,"carbon-oxygen lyase activity, acting on polysaccharides",molecular_function
65981,GO:0016838,Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.,"carbon-oxygen lyase activity, acting on phosphates",molecular_function
65982,GO:0016840,"Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH...",carbon-nitrogen lyase activity,molecular_function
65983,GO:0016841,Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.,ammonia-lyase activity,molecular_function
65984,GO:0016842,Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.,amidine-lyase activity,molecular_function
65985,GO:0016843,Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.,amine-lyase activity,molecular_function
65986,GO:0016844,Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = secologanin + tryptamine.,strictosidine synthase activity,molecular_function
65987,GO:0016846,Catalysis of the elimination of hydrogen sulfide or substituted H2S.,carbon-sulfur lyase activity,molecular_function
65988,GO:0016847,Catalysis of the reaction: S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H+. 1-aminocyclopropane-1-carboxylate (ACC) is a direct precursor of ethylene biosynthesis.,1-aminocyclopropane-1-carboxylate synthase activity,molecular_function
65989,GO:0016848,Catalysis of the breakage of a bond between carbon and any halogen atom.,carbon-halide lyase activity,molecular_function
65990,GO:0016849,"Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.",phosphorus-oxygen lyase activity,molecular_function
65991,GO:0016851,Catalysis of the reaction: ATP + H2O + Mg2+ + protoporphyrin IX = ADP + 3 H+ + Mg-protoporphyrin IX + phosphate.,magnesium chelatase activity,molecular_function
65992,GO:0016852,Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.,sirohydrochlorin cobaltochelatase activity,molecular_function
65993,GO:0016853,Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.,isomerase activity,molecular_function
65994,GO:0016854,Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.,racemase and epimerase activity,molecular_function
65995,GO:0016855,Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.,"racemase and epimerase activity, acting on amino acids and derivatives",molecular_function
65996,GO:0016856,Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.,"racemase and epimerase activity, acting on hydroxy acids and derivatives",molecular_function
65997,GO:0016857,Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.,"racemase and epimerase activity, acting on carbohydrates and derivatives",molecular_function
65998,GO:0016859,Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.,cis-trans isomerase activity,molecular_function
65999,GO:0016860,"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.",intramolecular oxidoreductase activity,molecular_function
66000,GO:0016861,"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.","intramolecular oxidoreductase activity, interconverting aldoses and ketoses",molecular_function
66001,GO:0016862,"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.","intramolecular oxidoreductase activity, interconverting keto- and enol-groups",molecular_function
66002,GO:0016863,"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.","intramolecular oxidoreductase activity, transposing C=C bonds",molecular_function
66003,GO:0016864,"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.","intramolecular oxidoreductase activity, transposing S-S bonds",molecular_function
66004,GO:0016866,Catalysis of the transfer of a functional group from one position to another within a single molecule.,intramolecular transferase activity,molecular_function
66005,GO:0016867,Catalysis of the transfer of an acyl group from one position to another within a single molecule.,intramolecular acyltransferase activity,molecular_function
66006,GO:0016868,Catalysis of the transfer of a phosphate group from one position to another within a single molecule.,intramolecular phosphotransferase activity,molecular_function
66007,GO:0016869,Catalysis of the transfer of an amino group from one position to another within a single molecule.,intramolecular aminotransferase activity,molecular_function
66008,GO:0016871,"Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.",cycloartenol synthase activity,molecular_function
66009,GO:0016872,The catalysis of certain rearrangements of a molecule to break or form a ring.,intramolecular lyase activity,molecular_function
66010,GO:0016874,"Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.",ligase activity,molecular_function
66011,GO:0016875,"Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming carbon-oxygen bonds",molecular_function
66012,GO:0016877,"Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming carbon-sulfur bonds",molecular_function
66013,GO:0016878,"Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",acid-thiol ligase activity,molecular_function
66014,GO:0016879,"Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming carbon-nitrogen bonds",molecular_function
66015,GO:0016880,"Catalysis of the ligation of an acid to ammonia (NH4+) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",acid-ammonia (or amide) ligase activity,molecular_function
66016,GO:0016881,"Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",acid-amino acid ligase activity,molecular_function
66017,GO:0016882,"Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",cyclo-ligase activity,molecular_function
66018,GO:0016884,"Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.","carbon-nitrogen ligase activity, with glutamine as amido-N-donor",molecular_function
66019,GO:0016885,"Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming carbon-carbon bonds",molecular_function
66020,GO:0016886,"Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming phosphoric ester bonds",molecular_function
66021,GO:0016887,"Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.",ATP hydrolysis activity,molecular_function
66022,GO:0016888,Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.,"DNA endonuclease activity, producing 5'-phosphomonoesters",molecular_function
66023,GO:0016889,Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.,"DNA endonuclease activity, producing 3'-phosphomonoesters",molecular_function
66024,GO:0016891,Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.,"RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism",molecular_function
66025,GO:0016892,Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.,"RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism",molecular_function
66026,GO:0016895,Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.,"DNA exonuclease activity, producing 5'-phosphomonoesters",molecular_function
66027,GO:0016896,Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.,"RNA exonuclease activity, producing 5'-phosphomonoesters",molecular_function
66028,GO:0016898,Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.,"oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor",molecular_function
66029,GO:0016899,Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.,"oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor",molecular_function
66030,GO:0016901,Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.,"oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor",molecular_function
66031,GO:0016903,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors",molecular_function
66032,GO:0016905,Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.,myosin heavy chain kinase activity,molecular_function
66033,GO:0016906,Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.,sterol 3-beta-glucosyltransferase activity,molecular_function
66034,GO:0016907,Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled acetylcholine receptor activity,molecular_function
66035,GO:0016913,"The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.",follicle-stimulating hormone activity,molecular_function
66036,GO:0016914,"A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.",follicle-stimulating hormone complex,cellular_component
66037,GO:0016917,"Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.",GABA receptor activity,molecular_function
66038,GO:0016918,"Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.",retinal binding,molecular_function
66039,GO:0016920,Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.,pyroglutamyl-peptidase activity,molecular_function
66040,GO:0016922,Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand.,nuclear receptor binding,molecular_function
66041,GO:0016925,The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.,protein sumoylation,biological_process
66042,GO:0016926,The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.,protein desumoylation,biological_process
66043,GO:0016929,An thiol-dependent isopeptidase activity that cleaves SUMO from a target protein to which it is conjugated.,deSUMOylase activity,molecular_function
66044,GO:0016933,Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,extracellularly glycine-gated ion channel activity,molecular_function
66045,GO:0016934,Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,extracellularly glycine-gated chloride channel activity,molecular_function
66046,GO:0016935,A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.,glycine-gated chloride channel complex,cellular_component
66047,GO:0016936,Binding to a glycoside in which the sugar group is galactose.,galactoside binding,molecular_function
66048,GO:0016937,"Catalysis of the reaction: a short-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.",short-chain fatty acyl-CoA dehydrogenase activity,molecular_function
66049,GO:0016938,A complex of two kinesin heavy chains and two kinesin light chains.,kinesin I complex,cellular_component
66050,GO:0016939,"A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.",kinesin II complex,cellular_component
66051,GO:0016941,Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.,natriuretic peptide receptor activity,molecular_function
66052,GO:0016942,A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.,insulin-like growth factor binding protein complex,cellular_component
66053,GO:0016964,Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.,alpha-2 macroglobulin receptor activity,molecular_function
66054,GO:0016966,Catalysis of the reaction: H2O + 2 ferricytochrome c + nitrous oxide = 2 H+ + 2 ferrocytochrome c + 2 nitric oxide.,nitric oxide reductase activity,molecular_function
66055,GO:0016971,"Catalysis of the reaction: [protein]-dithiol + O2 = [protein]-disulfide + H2O2 using FAD as a cofactor, leading to formation of disulfide bridges in proteins.",flavin-dependent sulfhydryl oxidase activity,molecular_function
66056,GO:0016972,Catalysis of the reaction: 2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + 2 H2O2.,thiol oxidase activity,molecular_function
66057,GO:0016973,The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.,poly(A)+ mRNA export from nucleus,biological_process
66058,GO:0016977,"Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.",chitosanase activity,molecular_function
66059,GO:0016979,Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP.,lipoate-protein ligase activity,molecular_function
66060,GO:0016980,Catalysis of the reaction: creatine + H2O = sarcosine + urea.,creatinase activity,molecular_function
66061,GO:0016984,"Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O.",ribulose-bisphosphate carboxylase activity,molecular_function
66062,GO:0016985,"Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.","mannan endo-1,4-beta-mannosidase activity",molecular_function
66063,GO:0016987,"Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.",sigma factor activity,molecular_function
66064,GO:0016989,"The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.",sigma factor antagonist activity,molecular_function
66065,GO:0016990,Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH4+.,arginine deiminase activity,molecular_function
66066,GO:0016992,Catalysis of the reaction: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S]2+ cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H+ = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe3+ + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin].,lipoate synthase activity,molecular_function
66067,GO:0016993,Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.,precorrin-8X methylmutase activity,molecular_function
66068,GO:0016994,Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.,precorrin-6A reductase activity,molecular_function
66069,GO:0016995,Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.,cholesterol oxidase activity,molecular_function
66070,GO:0016996,Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.,"endo-alpha-(2,8)-sialidase activity",molecular_function
66071,GO:0016997,Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.,alpha-sialidase activity,molecular_function
66072,GO:0016998,The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.,cell wall macromolecule catabolic process,biological_process
66073,GO:0016999,"The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.",antibiotic metabolic process,biological_process
66074,GO:0017000,"The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.",antibiotic biosynthetic process,biological_process
66075,GO:0017001,"The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.",antibiotic catabolic process,biological_process
66076,GO:0017002,Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.,activin receptor activity,molecular_function
66077,GO:0017003,The covalent linkage of heme and a protein.,protein-heme linkage,biological_process
66078,GO:0017004,"The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.",cytochrome complex assembly,biological_process
66079,GO:0017005,Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.,3'-tyrosyl-DNA phosphodiesterase activity,molecular_function
66080,GO:0017006,The covalent linking of a tetrapyrrole to a protein.,protein-tetrapyrrole linkage,biological_process
66081,GO:0017007,The covalent linkage of bilin and a protein.,protein-bilin linkage,biological_process
66082,GO:0017008,The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.,protein-phycobiliviolin linkage,biological_process
66083,GO:0017009,The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.,protein-phycocyanobilin linkage,biological_process
66084,GO:0017010,The linkage of the chromophore phycourobilin to phycoerythrins.,protein-phycourobilin linkage,biological_process
66085,GO:0017011,The linkage of the chromophore phycoerythrobilin to phycoerythrins.,protein-phycoerythrobilin linkage,biological_process
66086,GO:0017012,The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.,protein-phytochromobilin linkage,biological_process
66087,GO:0017013,The addition of a flavin group to a protein amino acid.,protein flavinylation,biological_process
66088,GO:0017014,The covalent addition of a nitric oxide group to an amino acid within a protein.,protein nitrosylation,biological_process
66089,GO:0017015,"Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.",regulation of transforming growth factor beta receptor signaling pathway,biological_process
66090,GO:0017017,Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.,MAP kinase tyrosine/serine/threonine phosphatase activity,molecular_function
66091,GO:0017018,Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.,myosin phosphatase activity,molecular_function
66092,GO:0017020,Binds to and modulates of the activity of myosin phosphatase.,myosin phosphatase regulator activity,molecular_function
66093,GO:0017022,Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.,myosin binding,molecular_function
66094,GO:0017023,An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. Composed of a PP1 catalytic subunit (PP1c/PPP1CB) and a myosin phosphatase targeting subunit (MYPT1/PPP1R12A).,myosin phosphatase complex,cellular_component
66095,GO:0017024,"Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.",myosin I binding,molecular_function
66096,GO:0017025,"Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).",TBP-class protein binding,molecular_function
66097,GO:0017032,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).,amino acid:potassium symporter activity,molecular_function
66098,GO:0017038,The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.,protein import,biological_process
66099,GO:0017040,Catalysis of the reaction: an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine.,N-acylsphingosine amidohydrolase activity,molecular_function
66100,GO:0017042,Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.,glycosylceramidase activity,molecular_function
66101,GO:0017044,"The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.",melanocyte-stimulating hormone activity,molecular_function
66102,GO:0017045,"The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.",corticotropin-releasing hormone activity,molecular_function
66103,GO:0017046,Binding to a peptide with hormonal activity in animals.,peptide hormone binding,molecular_function
66104,GO:0017051,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.",retinol dehydratase activity,molecular_function
66105,GO:0017053,A protein complex that possesses activity that prevents or downregulates transcription.,transcription repressor complex,cellular_component
66106,GO:0017054,"A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.",negative cofactor 2 complex,cellular_component
66107,GO:0017055,"Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.",negative regulation of RNA polymerase II transcription preinitiation complex assembly,biological_process
66108,GO:0017056,"The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.",structural constituent of nuclear pore,molecular_function
66109,GO:0017057,"Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+.",6-phosphogluconolactonase activity,molecular_function
66110,GO:0017058,"Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.",FH1 domain binding,molecular_function
66111,GO:0017059,"A protein complex that catalyses the condensation of L-serine with palmitoyl-CoA to form 3-ketosphinganine, the sphingoid base which is the starting point for all sphingolipids. In bacteria the enzyme is a cytoplasmic homodimer, whereas in eukaryotes the enzyme is a multiprotein complex localised to the endoplasmic reticulum. The eukaryotic complex consists of catalytic components (SPTLC1, SPTLC2 and SPTLC3 in humans; LCB1 and LCB2 in S. cerevisiae) and regulatory components, which include ac...",serine palmitoyltransferase complex,cellular_component
66112,GO:0017060,"Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.",3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity,molecular_function
66113,GO:0017061,Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.,S-methyl-5-thioadenosine phosphorylase activity,molecular_function
66114,GO:0017062,"The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.",respiratory chain complex III assembly,biological_process
66115,GO:0017064,Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.,fatty acid amide hydrolase activity,molecular_function
66116,GO:0017065,"Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.",single-strand selective uracil DNA N-glycosylase activity,molecular_function
66117,GO:0017067,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H+.",tyrosine-ester sulfotransferase activity,molecular_function
66118,GO:0017069,Binding to a small nuclear RNA (snRNA).,snRNA binding,molecular_function
66119,GO:0017070,Binding to a U6 small nuclear RNA (U6 snRNA).,U6 snRNA binding,molecular_function
66120,GO:0017071,A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.,intracellular cyclic nucleotide activated cation channel complex,cellular_component
66121,GO:0017075,Binding to a syntaxin-1 SNAP receptor.,syntaxin-1 binding,molecular_function
66122,GO:0017076,"Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.",purine nucleotide binding,molecular_function
66123,GO:0017077,"Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.",oxidative phosphorylation uncoupler activity,molecular_function
66124,GO:0017080,Binds to and modulates the activity of a sodium channel.,sodium channel regulator activity,molecular_function
66125,GO:0017081,Binds to and modulates the activity of a chloride channel.,chloride channel regulator activity,molecular_function
66126,GO:0017083,"Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R.",4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity,molecular_function
66127,GO:0017084,Catalysis of the reaction: ATP + H+ + L-glutamate + NADPH = ADP + L-glutamate 5-semialdehyde + NADP+ + phosphate.,delta1-pyrroline-5-carboxylate synthetase (NADP+) activity,molecular_function
66128,GO:0017085,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.",response to insecticide,biological_process
66129,GO:0017087,A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.,mitochondrial processing peptidase complex,cellular_component
66130,GO:0017089,"Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.",glycolipid transfer activity,molecular_function
66131,GO:0017090,"A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.",meprin A complex,cellular_component
66132,GO:0017095,"Catalysis of the reaction: alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 6-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H+.",heparan sulfate 6-sulfotransferase activity,molecular_function
66133,GO:0017096,Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.,acetylserotonin O-methyltransferase activity,molecular_function
66134,GO:0017098,"Binding to a sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.",sulfonylurea receptor binding,molecular_function
66135,GO:0017099,"Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.",very-long-chain fatty acyl-CoA dehydrogenase activity,molecular_function
66136,GO:0017101,"A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of...",aminoacyl-tRNA synthetase multienzyme complex,cellular_component
66137,GO:0017102,A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.,methionyl glutamyl tRNA synthetase complex,cellular_component
66138,GO:0017103,Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.,UTP:galactose-1-phosphate uridylyltransferase activity,molecular_function
66139,GO:0017105,"Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11Z)-delta-11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-CoA 11-(Z)-desaturase activity,molecular_function
66140,GO:0017108,"Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.",5'-flap endonuclease activity,molecular_function
66141,GO:0017109,"An enzyme complex that catalyzes the ligation of L-glutamate to L-cysteine, forming gamma-L-glutamyl-L-cysteine.",glutamate-cysteine ligase complex,cellular_component
66142,GO:0017110,Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate.,nucleoside diphosphate phosphatase activity,molecular_function
66143,GO:0017111,Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.,ribonucleoside triphosphate phosphatase activity,molecular_function
66144,GO:0017113,"Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.",dihydropyrimidine dehydrogenase (NADP+) activity,molecular_function
66145,GO:0017116,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.",single-stranded DNA helicase activity,molecular_function
66146,GO:0017117,A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.,single-stranded DNA-dependent ATP-dependent DNA helicase complex,cellular_component
66147,GO:0017118,Catalysis of the reaction: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] = (R)-N6-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H+.,lipoyltransferase activity,molecular_function
66148,GO:0017119,A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8.,COG complex,cellular_component
66149,GO:0017121,"The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).",plasma membrane phospholipid scrambling,biological_process
66150,GO:0017122,"A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits.",protein N-acetylglucosaminyltransferase complex,cellular_component
66151,GO:0017124,"Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.",SH3 domain binding,molecular_function
66152,GO:0017125,Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.,deoxycytidyl transferase activity,molecular_function
66153,GO:0017126,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.",nucleologenesis,biological_process
66154,GO:0017128,"Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.",phospholipid scramblase activity,molecular_function
66155,GO:0017129,Binding to a triester of glycerol.,triglyceride binding,molecular_function
66156,GO:0017130,Binding to a sequence of cytosine residues in an RNA molecule.,poly(C) RNA binding,molecular_function
66157,GO:0017131,Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.,uridine-rich cytoplasmic polyadenylylation element binding,molecular_function
66158,GO:0017133,"A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.",mitochondrial electron transfer flavoprotein complex,cellular_component
66159,GO:0017134,Binding to a fibroblast growth factor.,fibroblast growth factor binding,molecular_function
66160,GO:0017136,"Catalysis of the reaction: N(6)-acetyl-L-lysyl-[histone] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a histone to NAD, producing nicotinamide.","histone deacetylase activity, NAD-dependent",molecular_function
66161,GO:0017143,"The chemical reactions and pathways involving insecticides, chemicals used to kill insects.",insecticide metabolic process,biological_process
66162,GO:0017145,"The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.",stem cell division,biological_process
66163,GO:0017146,"An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene ...",NMDA selective glutamate receptor complex,cellular_component
66164,GO:0017147,"Binding to a Wnt-protein, a secreted growth factor involved in signaling.",Wnt-protein binding,molecular_function
66165,GO:0017148,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.",negative regulation of translation,biological_process
66166,GO:0017150,"Catalysis of the reaction: a 5,6-dihydrouridine in tRNA + NAD(P)+ = a uridine in tRNA + H+ + NAD(P)H.",tRNA dihydrouridine synthase activity,molecular_function
66167,GO:0017151,Binding to a DEAD/H-box RNA helicase.,DEAD/H-box RNA helicase binding,molecular_function
66168,GO:0017153,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).,sodium:dicarboxylate symporter activity,molecular_function
66169,GO:0017154,"Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",semaphorin receptor activity,molecular_function
66170,GO:0017156,"The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.",calcium-ion regulated exocytosis,biological_process
66171,GO:0017157,"Any process that modulates the frequency, rate or extent of exocytosis.",regulation of exocytosis,biological_process
66172,GO:0017158,"Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.",regulation of calcium ion-dependent exocytosis,biological_process
66173,GO:0017159,Catalysis of the reaction: (R)-pantetheine + H2O = (R)-pantothenate + cysteamine.,pantetheine hydrolase activity,molecular_function
66174,GO:0017161,"Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.","inositol-1,3,4-trisphosphate 4-phosphatase activity",molecular_function
66175,GO:0017162,Binding to an aryl hydrocarbon receptor.,aryl hydrocarbon receptor binding,molecular_function
66176,GO:0017166,"Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.",vinculin binding,molecular_function
66177,GO:0017168,Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + 2 H+ + phosphate.,5-oxoprolinase (ATP-hydrolyzing) activity,molecular_function
66178,GO:0017169,Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.,CDP-alcohol phosphatidyltransferase activity,molecular_function
66179,GO:0017171,Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).,serine hydrolase activity,molecular_function
66180,GO:0017172,Catalysis of the reaction: L-cysteine + O2 = 3-sulfino-L-alanine + H+.,cysteine dioxygenase activity,molecular_function
66181,GO:0017174,Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.,glycine N-methyltransferase activity,molecular_function
66182,GO:0017176,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.,phosphatidylinositol N-acetylglucosaminyltransferase activity,molecular_function
66183,GO:0017177,A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.,glucosidase II complex,cellular_component
66184,GO:0017178,Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.,diphthine-ammonia ligase activity,molecular_function
66185,GO:0017183,"The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.",protein histidyl modification to diphthamide,biological_process
66186,GO:0017185,The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.,peptidyl-lysine hydroxylation,biological_process
66187,GO:0017187,The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.,peptidyl-glutamic acid carboxylation,biological_process
66188,GO:0017188,Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H+.,L-aspartate N-acetyltransferase activity,molecular_function
66189,GO:0017190,The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.,N-terminal peptidyl-aspartic acid acetylation,biological_process
66190,GO:0017192,"The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.",N-terminal peptidyl-glutamine acetylation,biological_process
66191,GO:0017196,The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.,N-terminal peptidyl-methionine acetylation,biological_process
66192,GO:0018002,The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.,N-terminal peptidyl-glutamic acid acetylation,biological_process
66193,GO:0018003,The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.,peptidyl-lysine N6-acetylation,biological_process
66194,GO:0018004,The formylation of the N-terminal amino acid of proteins.,N-terminal protein formylation,biological_process
66195,GO:0018008,The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.,N-terminal peptidyl-glycine N-myristoylation,biological_process
66196,GO:0018009,The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.,N-terminal peptidyl-L-cysteine N-palmitoylation,biological_process
66197,GO:0018012,"The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.",N-terminal peptidyl-alanine trimethylation,biological_process
66198,GO:0018013,The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.,N-terminal peptidyl-glycine methylation,biological_process
66199,GO:0018016,"The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.",N-terminal peptidyl-proline dimethylation,biological_process
66200,GO:0018021,"The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).",peptidyl-histidine methylation,biological_process
66201,GO:0018022,"The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.",peptidyl-lysine methylation,biological_process
66202,GO:0018023,"The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.",peptidyl-lysine trimethylation,biological_process
66203,GO:0018025,Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.,calmodulin-lysine N-methyltransferase activity,molecular_function
66204,GO:0018026,The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.,peptidyl-lysine monomethylation,biological_process
66205,GO:0018027,"The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.",peptidyl-lysine dimethylation,biological_process
66206,GO:0018030,Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.,peptidyl-lysine N6-myristoyltransferase activity,molecular_function
66207,GO:0018031,Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.,peptidyl-lysine N6-palmitoyltransferase activity,molecular_function
66208,GO:0018057,"The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.",peptidyl-lysine oxidation,biological_process
66209,GO:0018063,The linkage of cytochromes and other heme proteins to heme.,cytochrome c-heme linkage,biological_process
66210,GO:0018064,Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.,protein-L-histidine N-tele-methyltransferase activity,molecular_function
66211,GO:0018070,The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.,peptidyl-serine phosphopantetheinylation,biological_process
66212,GO:0018076,The acetylation of the N-terminal lysine of proteins.,N-terminal peptidyl-lysine acetylation,biological_process
66213,GO:0018094,The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.,protein polyglycylation,biological_process
66214,GO:0018095,The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.,protein polyglutamylation,biological_process
66215,GO:0018103,A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.,protein C-linked glycosylation,biological_process
66216,GO:0018104,The process of covalently linking peptidoglycan (murein) to proteins.,peptidoglycan-protein cross-linking,biological_process
66217,GO:0018105,The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.,peptidyl-serine phosphorylation,biological_process
66218,GO:0018106,"The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).",peptidyl-histidine phosphorylation,biological_process
66219,GO:0018107,The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.,peptidyl-threonine phosphorylation,biological_process
66220,GO:0018108,The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.,peptidyl-tyrosine phosphorylation,biological_process
66221,GO:0018109,The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.,peptidyl-arginine phosphorylation,biological_process
66222,GO:0018111,Catalysis of the reaction: L-methionine = D-methionine.,methionine racemase activity,molecular_function
66223,GO:0018112,Catalysis of the reaction: L-proline = D-proline.,proline racemase activity,molecular_function
66224,GO:0018113,Catalysis of the reaction: L-lysine = D-lysine.,lysine racemase activity,molecular_function
66225,GO:0018114,Catalysis of the reaction: L-threonine = D-threonine.,threonine racemase activity,molecular_function
66226,GO:0018117,The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.,protein adenylylation,biological_process
66227,GO:0018119,"The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.",peptidyl-cysteine S-nitrosylation,biological_process
66228,GO:0018125,The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.,peptidyl-cysteine methylation,biological_process
66229,GO:0018126,The addition of a hydroxy group to a protein amino acid.,protein hydroxylation,biological_process
66230,GO:0018143,The formation of a covalent cross-link between a nucleic acid and a protein.,nucleic acid-protein covalent cross-linking,biological_process
66231,GO:0018144,The formation of a covalent cross-link between RNA and a protein.,RNA-protein covalent cross-linking,biological_process
66232,GO:0018146,"The chemical reactions and pathways resulting in the formation of keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated. Keratan sulfate chains can be covalently linked either to an asparagine residue (N-linked) of the core protein via a high mannose oligasacccharide linker or to s...",keratan sulfate proteoglycan biosynthetic process,biological_process
66233,GO:0018149,The formation of a covalent cross-link between or within protein chains.,peptide cross-linking,biological_process
66234,GO:0018153,The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.,isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine,biological_process
66235,GO:0018158,The modification of a protein amino acid by oxidation.,protein oxidation,biological_process
66236,GO:0018169,Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.,ribosomal S6-glutamic acid ligase activity,molecular_function
66237,GO:0018171,The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.,peptidyl-cysteine oxidation,biological_process
66238,GO:0018174,The linkage of protein to heme P460.,protein-heme P460 linkage,biological_process
66239,GO:0018175,The addition of a nucleotide to a protein amino acid.,protein nucleotidylation,biological_process
66240,GO:0018177,The addition of phospho-uridine to a protein amino acid.,protein uridylylation,biological_process
66241,GO:0018184,The modification of a protein amino acid by polyamination.,protein polyamination,biological_process
66242,GO:0018186,The covalent linkage of heme to peroxidase.,peroxidase-heme linkage,biological_process
66243,GO:0018188,"The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.",peptidyl-proline di-hydroxylation,biological_process
66244,GO:0018189,The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.,pyrroloquinoline quinone biosynthetic process,biological_process
66245,GO:0018190,The modification of a protein amino acid by formation of an ester or amide with octanoic acid.,protein octanoylation,biological_process
66246,GO:0018191,"The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.",peptidyl-serine octanoylation,biological_process
66247,GO:0018195,The modification of peptidyl-arginine.,peptidyl-arginine modification,biological_process
66248,GO:0018200,The modification of peptidyl-glutamic acid.,peptidyl-glutamic acid modification,biological_process
66249,GO:0018201,The modification of peptidyl-glycine.,peptidyl-glycine modification,biological_process
66250,GO:0018205,The modification of peptidyl-lysine.,peptidyl-lysine modification,biological_process
66251,GO:0018206,The modification of peptidyl-methionine.,peptidyl-methionine modification,biological_process
66252,GO:0018207,The modification of peptidyl-phenylalanine.,peptidyl-phenylalanine modification,biological_process
66253,GO:0018208,The modification of peptidyl-proline.,peptidyl-proline modification,biological_process
66254,GO:0018214,The addition of a carboxy group to a protein amino acid.,protein carboxylation,biological_process
66255,GO:0018215,The modification of a protein amino acid by phosphopantetheinylation.,protein phosphopantetheinylation,biological_process
66256,GO:0018216,The addition of a methyl group to an arginine residue in a protein.,peptidyl-arginine methylation,biological_process
66257,GO:0018217,The phosphorylation of peptidyl-aspartic acid.,peptidyl-aspartic acid phosphorylation,biological_process
66258,GO:0018230,The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.,peptidyl-L-cysteine S-palmitoylation,biological_process
66259,GO:0018237,Increases the activity of urease by promoting the incorporation of nickel into the active site.,urease activator activity,molecular_function
66260,GO:0018246,The formation of a linkage between a protein amino acid and coenzyme A.,protein-coenzyme A linkage,biological_process
66261,GO:0018247,"The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.",protein-phosphoribosyl dephospho-coenzyme A linkage,biological_process
66262,GO:0018249,The removal of a water group from a protein amino acid.,protein dehydration,biological_process
66263,GO:0018256,The addition of a formyl group to a protein amino acid.,protein formylation,biological_process
66264,GO:0018260,The addition of phospho-guanosine to a protein amino acid.,protein guanylylation,biological_process
66265,GO:0018262,"The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.",isopeptide cross-linking,biological_process
66266,GO:0018272,The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.,protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine,biological_process
66267,GO:0018277,The removal of an amino group from a protein amino acid.,protein deamination,biological_process
66268,GO:0018280,A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.,protein S-linked glycosylation,biological_process
66269,GO:0018282,"The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.",metal incorporation into metallo-sulfur cluster,biological_process
66270,GO:0018283,The incorporation of iron into a metallo-sulfur cluster.,iron incorporation into metallo-sulfur cluster,biological_process
66271,GO:0018289,The incorporation of molybdenum into a metallo-sulfur cluster.,molybdenum incorporation into metallo-sulfur cluster,biological_process
66272,GO:0018291,The incorporation of molybdenum into an iron-sulfur cluster.,molybdenum incorporation into iron-sulfur cluster,biological_process
66273,GO:0018293,The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).,protein-FAD linkage,biological_process
66274,GO:0018315,The incorporation of molybdenum into a molybdenum-molybdopterin complex.,molybdenum incorporation into molybdenum-molybdopterin complex,biological_process
66275,GO:0018316,The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.,peptide cross-linking via L-cystine,biological_process
66276,GO:0018335,The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.,protein succinylation,biological_process
66277,GO:0018336,The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.,peptidyl-tyrosine hydroxylation,biological_process
66278,GO:0018342,"The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.",protein prenylation,biological_process
66279,GO:0018343,The covalent attachment of a farnesyl group to a protein.,protein farnesylation,biological_process
66280,GO:0018344,The covalent attachment of a geranylgeranyl group to a protein.,protein geranylgeranylation,biological_process
66281,GO:0018345,The covalent attachment of a palmitoyl group to a protein.,protein palmitoylation,biological_process
66282,GO:0018352,The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.,protein-pyridoxal-5-phosphate linkage,biological_process
66283,GO:0018364,The addition of a methyl group to a glutamine residue in a protein.,peptidyl-glutamine methylation,biological_process
66284,GO:0018365,Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.,protein-serine epimerase activity,molecular_function
66285,GO:0018377,The covalent attachment of a myristoyl group to a protein.,protein myristoylation,biological_process
66286,GO:0018392,Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-be...,glycoprotein 3-alpha-L-fucosyltransferase activity,molecular_function
66287,GO:0018393,The addition of an acetyl group to a non-terminal lysine residue in a protein.,internal peptidyl-lysine acetylation,biological_process
66288,GO:0018394,The acetylation of peptidyl-lysine.,peptidyl-lysine acetylation,biological_process
66289,GO:0018395,The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.,peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine,biological_process
66290,GO:0018400,The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.,peptidyl-proline hydroxylation to 3-hydroxy-L-proline,biological_process
66291,GO:0018401,"The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.",peptidyl-proline hydroxylation to 4-hydroxy-L-proline,biological_process
66292,GO:0018410,The alteration of the C-terminal amino acid residue in a protein.,C-terminal protein amino acid modification,biological_process
66293,GO:0018414,The incorporation of nickel into a metallo-sulfur cluster.,nickel incorporation into metallo-sulfur cluster,biological_process
66294,GO:0018419,"The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.",protein catenane formation,biological_process
66295,GO:0018422,Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.,GDP-mannose:serine-protein mannose-1-phosphotransferase activity,molecular_function
66296,GO:0018423,Catalysis of the reaction: S-adenosyl-L-methionine + [protein]-L-leucine = S-adenosyl-L-homocysteine + [protein]-L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.,protein C-terminal leucine carboxyl O-methyltransferase activity,molecular_function
66297,GO:0018427,The incorporation of copper into a metallo-sulfur cluster.,copper incorporation into metallo-sulfur cluster,biological_process
66298,GO:0018428,The incorporation of copper into a copper-sulfur cluster.,copper incorporation into copper-sulfur cluster,biological_process
66299,GO:0018444,A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.,translation release factor complex,cellular_component
66300,GO:0018445,"The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.",prothoracicotrophic hormone activity,molecular_function
66301,GO:0018449,Catalysis of the reaction: (S)-1-phenylethanol + NAD+ = acetophenone + H+ + NADH.,1-phenylethanol dehydrogenase activity,molecular_function
66302,GO:0018452,"Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.",5-exo-hydroxycamphor dehydrogenase activity,molecular_function
66303,GO:0018454,Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.,acetoacetyl-CoA reductase activity,molecular_function
66304,GO:0018455,Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+.,alcohol dehydrogenase [NAD(P)+] activity,molecular_function
66305,GO:0018456,Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.,aryl-alcohol dehydrogenase (NAD+) activity,molecular_function
66306,GO:0018457,Catalysis of the reaction: NAD+ + perillyl alcohol = H+ + NADH + perillyl aldehyde.,perillyl-alcohol dehydrogenase (NAD+) activity,molecular_function
66307,GO:0018458,"Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD+ = (6R)-isoperitenone + H+ + NADH.",isopiperitenol dehydrogenase activity,molecular_function
66308,GO:0018459,"Catalysis of the reaction: (1S,5R)-carveol + NADP+ = (R)-carvone + H+ + NADPH.",carveol dehydrogenase activity,molecular_function
66309,GO:0018460,Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.,cyclohexanol dehydrogenase activity,molecular_function
66310,GO:0018461,Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.,fluoren-9-ol dehydrogenase activity,molecular_function
66311,GO:0018462,Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + H+ + NADH.,4-(hydroxymethyl)benzenesulfonate dehydrogenase activity,molecular_function
66312,GO:0018463,Catalysis of the reaction: 6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + H+ + NADH.,6-hydroxyhexanoate dehydrogenase activity,molecular_function
66313,GO:0018464,Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD+ = 3-oxopimelyl-CoA + H+ + NADH.,3-hydroxypimeloyl-CoA dehydrogenase activity,molecular_function
66314,GO:0018465,Catalysis of the reaction: O2 + vanillyl alcohol = H2O2 + vanillin.,vanillyl-alcohol oxidase activity,molecular_function
66315,GO:0018467,Catalysis of the reaction: formaldehyde + H2O + NAD+ = formate + 2 H+ + NADH.,formaldehyde dehydrogenase (NAD+) activity,molecular_function
66316,GO:0018474,Catalysis of the reaction: 2-formylbenzoate + H2O + NAD+ = 2 H+ + NADH + phthalate.,2-formylbenzoate dehydrogenase (NAD+) activity,molecular_function
66317,GO:0018477,Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.,benzaldehyde dehydrogenase (NADP+) activity,molecular_function
66318,GO:0018478,Catalysis of the reaction: 3-oxopropanoate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.,"malonate-semialdehyde dehydrogenase (acetylating, [NAD(P)+]) activity",molecular_function
66319,GO:0018479,Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.,benzaldehyde dehydrogenase (NAD+) activity,molecular_function
66320,GO:0018480,"Catalysis of the reaction: 2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ + H2O = (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + NADH + 2 H+.",5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase (NAD+) activity,molecular_function
66321,GO:0018481,"Catalysis of the reaction: cis,trans-4-hydroxymuconate semialdehyde + NAD+ + H2O = maleylacetate + NADH + 2 H+.",4-hydroxymuconic-semialdehyde dehydrogenase (NAD+) activity,molecular_function
66322,GO:0018482,Catalysis of the reaction: 4-formylbenzenesulfonate + NAD+ + H2O = 4-sulfobenzoate + NADH + 2 H+.,4-formylbenzenesulfonate dehydrogenase (NAD+) activity,molecular_function
66323,GO:0018483,Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = hexanedioate + NADPH + 2 H+.,6-oxohexanoate dehydrogenase (NADP+) activity,molecular_function
66324,GO:0018484,Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.,4-hydroxybenzaldehyde dehydrogenase (NAD+) activity,molecular_function
66325,GO:0018485,Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.,salicylaldehyde dehydrogenase (NAD+) activity,molecular_function
66326,GO:0018488,Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic carboxylate + H2O2 + H+.,aryl-aldehyde oxidase activity,molecular_function
66327,GO:0018489,"Catalysis of the reaction: H+ + NADH + O2 + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD+.",vanillate monooxygenase activity,molecular_function
66328,GO:0018490,Catalysis of the reaction: 2 3-(4-hydroxyphenyl)pyruvate + O2 = 2 4-hydroxyphenylacetate + 2 CO2.,4-hydroxyphenylpyruvate oxidase activity,molecular_function
66329,GO:0018493,Catalysis of the reaction: N-formylmethanofuran + A + H2O + H+ = AH(2) + CO2 + methanofuran.,formylmethanofuran dehydrogenase activity,molecular_function
66330,GO:0018494,"Catalysis of the reactions: (1R,4R)-dihydrocarvone + A = (R)-carvone + AH2, and (1R,4S)-isodihydrocarvone + A = (S)-carvone + AH2.",carvone reductase activity,molecular_function
66331,GO:0018498,"Catalysis of the reaction: 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ = 3-(2,3-dihydroxyphenyl)propanoate + H+ + NADH. Also converts (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate to (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate.","2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity",molecular_function
66332,GO:0018502,"Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.","2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity",molecular_function
66333,GO:0018504,"Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.","cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity",molecular_function
66334,GO:0018505,"Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.","cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity",molecular_function
66335,GO:0018506,Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.,maleylacetate reductase activity,molecular_function
66336,GO:0018507,"Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD+ = H+ + NADH + phenanthrene-3,4-diol.","cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity",molecular_function
66337,GO:0018509,"Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.","cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity",molecular_function
66338,GO:0018510,Catalysis of the reaction: dihydrophloroglucinol + NADP+ = H+ + NADPH + phloroglucinol.,phloroglucinol reductase activity,molecular_function
66339,GO:0018511,"Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ = 2,3-dihydroxy-p-cumate + H+ + NADH.","2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity",molecular_function
66340,GO:0018513,"Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+ = 1,2-dihydroxydibenzothiophene + H+ + NADH.",dibenzothiophene dihydrodiol dehydrogenase activity,molecular_function
66341,GO:0018515,"Catalysis of the reaction: NAD+ + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H+ + NADH.",pimeloyl-CoA dehydrogenase activity,molecular_function
66342,GO:0018516,"Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP+ = 2,4-dichlorobenzoyl-CoA + NADPH.","2,4-dichlorobenzoyl-CoA reductase activity",molecular_function
66343,GO:0018517,"Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + H+ + NADH.","phthalate 4,5-cis-dihydrodiol dehydrogenase activity",molecular_function
66344,GO:0018518,"Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H+ + NADH.","5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity",molecular_function
66345,GO:0018519,"Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD+ = 3-ethylcatechol + H+ + NADH.",cis-dihydroethylcatechol dehydrogenase activity,molecular_function
66346,GO:0018520,"Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.","cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity",molecular_function
66347,GO:0018521,"Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH.","1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity",molecular_function
66348,GO:0018522,"Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H2O + benzoyl-CoA + reduced ferredoxin.",benzoyl-CoA reductase activity,molecular_function
66349,GO:0018523,Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.,quinoline 2-oxidoreductase activity,molecular_function
66350,GO:0018525,Catalysis of the reaction: oxidized 2[4Fe-4S]-[ferredoxin] + benzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + reduced 2[4Fe-4S]-[ferredoxin] + 2 H+.,4-hydroxybenzoyl-CoA reductase activity,molecular_function
66351,GO:0018527,Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + H2O2 + NH4+.,cyclohexylamine oxidase activity,molecular_function
66352,GO:0018529,Catalysis of the reaction: nitrilotriacetate + FMNH2 + O2 = aminodiacetate + FMN + glyoxylate + H2O.,nitrilotriacetate monooxygenase activity,molecular_function
66353,GO:0018530,Catalysis of the reaction: (R)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2.,(R)-6-hydroxynicotine oxidase activity,molecular_function
66354,GO:0018531,Catalysis of the reaction: (S)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2.,(S)-6-hydroxynicotine oxidase activity,molecular_function
66355,GO:0018535,Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.,nicotine dehydrogenase activity,molecular_function
66356,GO:0018537,"Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H+ = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.","coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity",molecular_function
66357,GO:0018541,"Catalysis of the reaction: 1,4-benzoquinone + H+ + NADPH = hydroquinone + NADP+.",p-benzoquinone reductase (NADPH) activity,molecular_function
66358,GO:0018546,Catalysis of the reaction: H2O + N-phenylhydroxylamine + 2 NADP+ = 2 H+ + 2 NADPH + nitrobenzene.,nitrobenzene nitroreductase (NADPH) activity,molecular_function
66359,GO:0018549,Catalysis of the reaction: methanethiol + O2 + H2O = hydrogen sulfide + formaldehyde + H2O2 + H+.,methanethiol oxidase activity,molecular_function
66360,GO:0018551,Catalysis of the reactions: [DsrC protein]-trisulfide + 3 H2O + NAD+ = [DsrC protein]-dithiol + 3 H+ + NADH + sulfite.,dissimilatory sulfite reductase (NADH) activity,molecular_function
66361,GO:0018554,"Catalysis of the reaction: naphthalene-1,2-diol + O2 = 2-hydroxychromene-2-carboxylate + H+.","1,2-dihydroxynaphthalene dioxygenase activity",molecular_function
66362,GO:0018564,"Catalysis of the reaction: 9H-carbazole + H+ + NAD(P)H + O2 = 2'-aminobiphenyl-2,3-diol + NAD(P)+.","carbazole 1,9a-dioxygenase [NAD(P)H] activity",molecular_function
66363,GO:0018570,"Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.","p-cumate 2,3-dioxygenase activity",molecular_function
66364,GO:0018571,"Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.","2,3-dihydroxy-p-cumate dioxygenase activity",molecular_function
66365,GO:0018576,"Catalysis of the reaction: catechol + O2 = cis,cis-muconate.","catechol 1,2-dioxygenase activity",molecular_function
66366,GO:0018577,Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.,"catechol 2,3-dioxygenase activity",molecular_function
66367,GO:0018578,"Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.","protocatechuate 3,4-dioxygenase activity",molecular_function
66368,GO:0018579,Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.,"protocatechuate 4,5-dioxygenase activity",molecular_function
66369,GO:0018580,Catalysis of the reaction: ethylnitronate + O2 = acetaldehyde + nitrite.,nitronate monooxygenase activity,molecular_function
66370,GO:0018582,Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.,"1-hydroxy-2-naphthoate 1,2-dioxygenase activity",molecular_function
66371,GO:0018583,"Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.","biphenyl-2,3-diol 1,2-dioxygenase activity",molecular_function
66372,GO:0018592,"Catalysis of the reaction: 4-nitrocatechol + NAD(P)H + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(P)+ + H2O.",4-nitrocatechol 4-monooxygenase activity,molecular_function
66373,GO:0018597,Catalysis of the reaction: AH2 + NH4+ + O2 = A + H+ + H2O + hydroxylamine.,ammonia monooxygenase activity,molecular_function
66374,GO:0018601,Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.,4-nitrophenol 2-monooxygenase activity,molecular_function
66375,GO:0018602,"Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.","2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity",molecular_function
66376,GO:0018610,"Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.","dibenzofuran 4,4a-dioxygenase activity",molecular_function
66377,GO:0018616,"Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.",trihydroxytoluene dioxygenase activity,molecular_function
66378,GO:0018618,Catalysis of the reaction: anthranilate + NAD(P)H + O2 + 3 H+ = catechol + NH4+ + CO2 + NAD(P)+.,"anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity",molecular_function
66379,GO:0018619,"Catalysis of the reaction: benzene + NADH + O2 + H+ = cis-1,2-dihydrobenzene-1,2-diol + NAD+.","benzene 1,2-dioxygenase activity",molecular_function
66380,GO:0018620,"Catalysis of the reaction: phthalate + NADH + O2 + H+ = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+.","phthalate 4,5-dioxygenase activity",molecular_function
66381,GO:0018621,"Catalysis of the reaction: 4-sulfobenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + sulfite.","4-sulfobenzoate 3,4-dioxygenase activity",molecular_function
66382,GO:0018622,"Catalysis of the reaction: 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.","4-chlorophenylacetate 3,4-dioxygenase activity",molecular_function
66383,GO:0018623,"Catalysis of the reaction: benzoate + NADH + O2 + H+ = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+.","benzoate 1,2-dioxygenase activity",molecular_function
66384,GO:0018624,"Catalysis of the reaction: toluene + NADH + O2 + H+ = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.",toluene dioxygenase activity,molecular_function
66385,GO:0018625,"Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.","naphthalene 1,2-dioxygenase activity",molecular_function
66386,GO:0018626,Catalysis of the reaction: a 2-halobenzoate + NADH + O2 + H+ = a halide anion + catechol + CO2 + NAD+.,"2-halobenzoate 1,2-dioxygenase activity",molecular_function
66387,GO:0018627,"Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4. 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.","2-aminobenzenesulfonate 2,3-dioxygenase activity",molecular_function
66388,GO:0018628,"Catalysis of the reaction: terephthalate + NADH + O2 + H+ = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+.","terephthalate 1,2-dioxygenase activity",molecular_function
66389,GO:0018629,"Catalysis of the reaction: quinolin-2-ol + NADH + O2 + H+ = 5,6-dihydroquinoline-2,5,6-triol + NAD+.","2-hydroxyquinoline 5,6-dioxygenase activity",molecular_function
66390,GO:0018631,Catalysis of the reaction: 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase] = (2-hydroxyphenyl)acetate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,phenylacetate 2-hydroxylase activity,molecular_function
66391,GO:0018632,Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.,4-nitrophenol 4-monooxygenase activity,molecular_function
66392,GO:0018633,Catalysis of the reaction: dimethyl sulfide + H+ + NADH + O2 = formaldehyde + H2O + methanethiol + NAD+.,dimethyl sulfide monooxygenase activity,molecular_function
66393,GO:0018634,Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.,alpha-pinene monooxygenase (NADH) activity,molecular_function
66394,GO:0018637,"Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NAD(P)H + 2 H+ = NAD(P)+ + H2O + CO2 + 1,2-dihydroxynaphthalene.",1-hydroxy-2-naphthoate hydroxylase activity,molecular_function
66395,GO:0018638,Catalysis of the reaction: toluene + H+ + NADH + O2 = 4-methylphenol + H2O + NAD+.,toluene 4-monooxygenase activity,molecular_function
66396,GO:0018640,"Catalysis of the reaction: dibenzothiophene + 2 FMNH2 + 2 O2 = dibenzothiophene 5,5-dioxide + 2 FMN + 2 H2O + 2 H+.",dibenzothiophene monooxygenase activity,molecular_function
66397,GO:0018644,Catalysis of the reaction: toluene + H+ + NADH + O2 = 2-hydroxytoluene + H2O + NAD+.,toluene 2-monooxygenase activity,molecular_function
66398,GO:0018645,"Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.",alkene monooxygenase activity,molecular_function
66399,GO:0018648,Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.,methanesulfonate monooxygenase activity,molecular_function
66400,GO:0018652,Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.,toluene-sulfonate methyl-monooxygenase activity,molecular_function
66401,GO:0018658,Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.,salicylate 1-monooxygenase activity,molecular_function
66402,GO:0018659,Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.,4-hydroxybenzoate 3-monooxygenase activity,molecular_function
66403,GO:0018661,"Catalysis of the reaction: H+ + NADH + O2 + orcinol = 2,3,5-trihydroxytoluene + H2O + NAD+.",orcinol 2-monooxygenase activity,molecular_function
66404,GO:0018662,Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.,phenol 2-monooxygenase activity,molecular_function
66405,GO:0018663,"Catalysis of the reaction: 2,6-dihydroxypyridine + H+ + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD+.","2,6-dihydroxypyridine 3-monooxygenase activity",molecular_function
66406,GO:0018664,Catalysis of the reaction: benzoate + H+ + NADPH + O2 = 4-hydroxybenzoate + H2O + NADP+.,benzoate 4-monooxygenase activity,molecular_function
66407,GO:0018665,Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.,4-hydroxyphenylacetate 1-monooxygenase activity,molecular_function
66408,GO:0018666,"Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.","2,4-dichlorophenol 6-monooxygenase activity",molecular_function
66409,GO:0018667,Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.,cyclohexanone monooxygenase activity,molecular_function
66410,GO:0018668,"Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.",3-hydroxybenzoate 4-monooxygenase activity,molecular_function
66411,GO:0018669,"Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADH + O2 = 2,5-dihydroxybenzoate + H2O + NAD+.",3-hydroxybenzoate 6-monooxygenase activity,molecular_function
66412,GO:0018670,Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.,4-aminobenzoate 1-monooxygenase activity,molecular_function
66413,GO:0018671,"Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.",4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity,molecular_function
66414,GO:0018672,"Catalysis of the reaction: anthranilate + 2 H+ + NADPH + O2 = 2,3-dihydroxybenzoate + NADP+ + NH4.",anthranilate 3-monooxygenase (deaminating) activity,molecular_function
66415,GO:0018673,Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.,anthraniloyl-CoA monooxygenase activity,molecular_function
66416,GO:0018674,"Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,6R)-isopiperitenol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",(S)-limonene 3-monooxygenase activity,molecular_function
66417,GO:0018675,"Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,5R)-carveol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",(S)-limonene 6-monooxygenase activity,molecular_function
66418,GO:0018676,Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-perillyl alcohol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,(S)-limonene 7-monooxygenase activity,molecular_function
66419,GO:0018677,Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.,pentachlorophenol monooxygenase activity,molecular_function
66420,GO:0018678,Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.,4-hydroxybenzoate 1-hydroxylase activity,molecular_function
66421,GO:0018679,"Catalysis of the reaction: dibenzothiophene 5,5-dioxide + FMNH2 + NADH + O2 = 2'-hydroxybiphenyl-2-sulfinate + FMN + H+ + H2O + NAD+.",dibenzothiophene sulfone monooxygenase (NADH) activity,molecular_function
66422,GO:0018683,Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.,camphor 5-monooxygenase activity,molecular_function
66423,GO:0018684,"Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O.","2,5-diketocamphane 1,2-monooxygenase activity",molecular_function
66424,GO:0018685,Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.,alkane 1-monooxygenase activity,molecular_function
66425,GO:0018687,"Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.","biphenyl 2,3-dioxygenase activity",molecular_function
66426,GO:0018690,Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O2 = 4-hydroxybenzoate + A + formaldehyde + H2O.,4-methoxybenzoate monooxygenase (O-demethylating) activity,molecular_function
66427,GO:0018693,Catalysis of the reaction: A + ethylbenzene + H2O = (S)-1-phenylethanol + AH(2).,ethylbenzene hydroxylase activity,molecular_function
66428,GO:0018694,Catalysis of the reaction: 2 H+ + O2 + p-cymene + 2 reduced [2Fe-2S]-[ferredoxin] = 4-isopropylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].,p-cymene methyl hydroxylase activity,molecular_function
66429,GO:0018695,Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.,4-cresol dehydrogenase (hydroxylating) activity,molecular_function
66430,GO:0018698,Catalysis of the reaction: AH2 + chloroethene = A + chloride + ethene + H+.,chloroethene reductive dehalogenase activity,molecular_function
66431,GO:0018706,"Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.",pyrogallol hydroxytransferase activity,molecular_function
66432,GO:0018708,Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.,thiol S-methyltransferase activity,molecular_function
66433,GO:0018710,Catalysis of the reaction: acetone + ATP + CO2 + 2 H2O = acetoacetate + AMP + 4 H+ + 2 phosphate.,acetone carboxylase activity,molecular_function
66434,GO:0018719,Catalysis of the reaction: 6-aminohexanoate + 2-oxoglutarate = 6-oxohexanoate + L-glutamate.,6-aminohexanoate:2-oxoglutarate transaminase activity,molecular_function
66435,GO:0018720,Catalysis of the reaction: phenol + X-phosphate = XH + phenylphosphate.,phenol kinase activity,molecular_function
66436,GO:0018729,Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.,propionate CoA-transferase activity,molecular_function
66437,GO:0018730,Catalysis of the reaction: trans-glutaconate + acetyl-CoA = (2E)-glutaconyl-CoA + acetate.,glutaconate CoA-transferase activity,molecular_function
66438,GO:0018738,Catalysis of the reaction: S-formylglutathione + H2O = formate + glutathione + H+.,S-formylglutathione hydrolase activity,molecular_function
66439,GO:0018739,Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H+.,4-hydroxybenzoyl-CoA thioesterase activity,molecular_function
66440,GO:0018740,Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H2O = biphenyl-2-ol + sulfite.,2'-hydroxybiphenyl-2-sulfinate desulfinase activity,molecular_function
66441,GO:0018741,Catalysis of the reaction: a primary linear alkyl sulfate ester + H2O = a primary alcohol + H+ + sulfate.,linear primary-alkylsulfatase activity,molecular_function
66442,GO:0018744,"Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.","limonene-1,2-epoxide hydrolase activity",molecular_function
66443,GO:0018750,Catalysis of the reaction: biuret + H2O = urea-1-carboxylate + NH4+.,biuret amidohydrolase activity,molecular_function
66444,GO:0018753,Catalysis of the reaction: cyanurate + H2O = 1-carboxybiuret + H+.,cyanuric acid amidohydrolase activity,molecular_function
66445,GO:0018756,Catalysis of the reaction: ammeline + H2O = ammelide + NH4+. Also converts melamine to ammeline.,ammeline aminohydrolase activity,molecular_function
66446,GO:0018759,"Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H+.",methenyltetrahydromethanopterin cyclohydrolase activity,molecular_function
66447,GO:0018760,Catalysis of the reaction: H2O + 2 H+ + thiocyanate = carbonyl sulfide + NH4.,thiocyanate hydrolase activity,molecular_function
66448,GO:0018761,"Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.",bromoxynil nitrilase activity,molecular_function
66449,GO:0018762,Catalysis of the reaction: an aliphatic nitrile + 2 H2O = a carboxylate + NH4+.,aliphatic nitrilase activity,molecular_function
66450,GO:0018763,"Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.",hydroxydechloroatrazine ethylaminohydrolase activity,molecular_function
66451,GO:0018764,Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.,N-isopropylammelide isopropylaminohydrolase activity,molecular_function
66452,GO:0018765,"Catalysis of the reaction: (2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + acetate + H+.","2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity",molecular_function
66453,GO:0018768,"Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H+.","2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity",molecular_function
66454,GO:0018771,"Catalysis of the reaction: (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + H+ + succinate.","2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity",molecular_function
66455,GO:0018773,Catalysis of the reaction: acetylpyruvate + H2O = acetate + H+ + pyruvate.,acetylpyruvate hydrolase activity,molecular_function
66456,GO:0018774,"Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = 2-oxopent-4-enoate + benzoate + H+.","2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity",molecular_function
66457,GO:0018775,"Catalysis of the reaction: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O = 2-oxopent-4-enoate + formate + H+.",2-hydroxymuconate-semialdehyde hydrolase activity,molecular_function
66458,GO:0018784,Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.,(S)-2-haloacid dehalogenase activity,molecular_function
66459,GO:0018785,Catalysis of the reaction: haloacetate + H2O = glycolate + halide.,haloacetate dehalogenase activity,molecular_function
66460,GO:0018786,Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.,haloalkane dehalogenase activity,molecular_function
66461,GO:0018787,Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + chloride + H+.,4-chlorobenzoyl-CoA dehalogenase activity,molecular_function
66462,GO:0018788,Catalysis of the reaction: atrazine + H2O = chloride + H+ + hydroxyatrazine.,atrazine chlorohydrolase activity,molecular_function
66463,GO:0018789,Catalysis of the reaction: cyclohexylsulfamate + H2O = cyclohexylamine + sulfate.,cyclamate sulfohydrolase activity,molecular_function
66464,GO:0018796,"Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.","4,5-dihydroxyphthalate decarboxylase activity",molecular_function
66465,GO:0018798,Catalysis of the reaction: gallate + H+ = CO2 + pyrogallol.,gallate decarboxylase activity,molecular_function
66466,GO:0018799,Catalysis of the reaction: 4-hydroxybenzoate + H+ = CO2 + phenol.,4-hydroxybenzoate decarboxylase activity,molecular_function
66467,GO:0018800,"Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.","5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity",molecular_function
66468,GO:0018801,Catalysis of the reaction: (2E)-glutaconyl-CoA + Na+(in) + H+ = (2E)-butenoyl-CoA + Na+(out) + CO2.,glutaconyl-CoA decarboxylase activity,molecular_function
66469,GO:0018803,Catalysis of the reaction: (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate + pyruvate.,4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity,molecular_function
66470,GO:0018805,Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.,benzylsuccinate synthase activity,molecular_function
66471,GO:0018807,"Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.",6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity,molecular_function
66472,GO:0018812,Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O.,3-hydroxyacyl-CoA dehydratase activity,molecular_function
66473,GO:0018813,Catalysis of the reaction: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde + pyruvate. A broad range of aldehydes and 4-substituted 2-oxobut-3-enoates are accepted as substrates.,trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity,molecular_function
66474,GO:0018814,Catalysis of the reaction: (trans)-phenylacetaldoxime = H2O + phenylacetonitrile.,phenylacetaldoxime dehydratase activity,molecular_function
66475,GO:0018817,"Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.","2-oxo-hept-3-ene-1,7-dioate hydratase activity",molecular_function
66476,GO:0018818,Catalysis of the reaction: acetaldehyde = acetylene + H2O.,acetylene hydratase activity,molecular_function
66477,GO:0018819,Catalysis of the reaction: (R)-lactoyl-CoA = acryloyl-CoA + H2O.,lactoyl-CoA dehydratase activity,molecular_function
66478,GO:0018820,Catalysis of the reaction: urea = cyanamide + H2O.,cyanamide hydratase activity,molecular_function
66479,GO:0018822,Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.,nitrile hydratase activity,molecular_function
66480,GO:0018823,"Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-enecarbonyl-CoA.","cyclohexa-1,5-dienecarbonyl-CoA hydratase activity",molecular_function
66481,GO:0018824,Catalysis of the reaction: N-phenylhydroxylamine = 2-aminophenol.,(hydroxyamino)benzene mutase activity,molecular_function
66482,GO:0018826,Catalysis of the reaction: L-methionine + H2O = methanethiol + 2-oxobutanoate + NH4+.,methionine gamma-lyase activity,molecular_function
66483,GO:0018833,"Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H+.",DDT-dehydrochlorinase activity,molecular_function
66484,GO:0018834,Catalysis of the reaction: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H+.,dichloromethane dehalogenase activity,molecular_function
66485,GO:0018835,"Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).",carbon phosphorus lyase activity,molecular_function
66486,GO:0018836,Catalysis of the reaction: an alkylmercury + H+ = an alkane + Hg2+.,alkylmercury lyase activity,molecular_function
66487,GO:0018838,Catalysis of the reaction: (S)-mandelate = (R)-mandelate.,mandelate racemase activity,molecular_function
66488,GO:0018845,Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.,2-hydroxychromene-2-carboxylate isomerase activity,molecular_function
66489,GO:0018846,Catalysis of the reaction: styrene oxide = phenylacetaldehyde.,styrene-oxide isomerase activity,molecular_function
66490,GO:0018849,"Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.",muconate cycloisomerase activity,molecular_function
66491,GO:0018850,"Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.",chloromuconate cycloisomerase activity,molecular_function
66492,GO:0018851,"Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.",alpha-pinene-oxide decyclase activity,molecular_function
66493,GO:0018852,"Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.",dichloromuconate cycloisomerase activity,molecular_function
66494,GO:0018855,"Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.","2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity",molecular_function
66495,GO:0018858,Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate.,benzoate-CoA ligase activity,molecular_function
66496,GO:0018859,Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.,4-hydroxybenzoate-CoA ligase activity,molecular_function
66497,GO:0018860,Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.,anthranilate-CoA ligase activity,molecular_function
66498,GO:0018861,"Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.",4-chlorobenzoate-CoA ligase activity,molecular_function
66499,GO:0018862,Catalysis of the reaction: 4-hydroxybenzoate + H+ + phosphate = CO2 + H2O + phenyl phosphate.,phenyl-phosphate phosphatase/carboxylase activity,molecular_function
66500,GO:0018867,"The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.",alpha-pinene metabolic process,biological_process
66501,GO:0018872,"The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.",arsonoacetate metabolic process,biological_process
66502,GO:0018874,"The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.",benzoate metabolic process,biological_process
66503,GO:0018879,"The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).",biphenyl metabolic process,biological_process
66504,GO:0018880,"The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.",4-chlorobiphenyl metabolic process,biological_process
66505,GO:0018885,"The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.",carbon tetrachloride metabolic process,biological_process
66506,GO:0018890,"The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.",cyanamide metabolic process,biological_process
66507,GO:0018893,"The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.",dibenzofuran metabolic process,biological_process
66508,GO:0018894,"The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.",dibenzo-p-dioxin metabolic process,biological_process
66509,GO:0018896,"The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.",dibenzothiophene catabolic process,biological_process
66510,GO:0018900,"The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.",dichloromethane metabolic process,biological_process
66511,GO:0018901,"The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.","2,4-dichlorophenoxyacetic acid metabolic process",biological_process
66512,GO:0018907,"The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.",dimethyl sulfoxide metabolic process,biological_process
66513,GO:0018909,"The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.",dodecyl sulfate metabolic process,biological_process
66514,GO:0018910,"The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.",benzene metabolic process,biological_process
66515,GO:0018911,"The chemical reactions and pathways resulting in the breakdown of 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.","1,2,4-trichlorobenzene catabolic process",biological_process
66516,GO:0018914,"The chemical reactions and pathways resulting in the breakdown of chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.",chlorobenzene catabolic process,biological_process
66517,GO:0018915,"The chemical reactions and pathways resulting in the breakdown of ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.",ethylbenzene catabolic process,biological_process
66518,GO:0018916,"The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.",nitrobenzene metabolic process,biological_process
66519,GO:0018919,"The chemical reactions and pathways  resulting in the breakdown of  gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.","gamma-1,2,3,4,5,6-hexachlorocyclohexane catabolic process",biological_process
66520,GO:0018920,"The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.",glyphosate metabolic process,biological_process
66521,GO:0018924,"The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.",mandelate metabolic process,biological_process
66522,GO:0018933,"The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.",nicotine metabolic process,biological_process
66523,GO:0018937,"The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.",nitroglycerin metabolic process,biological_process
66524,GO:0018942,"The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.",organometal metabolic process,biological_process
66525,GO:0018958,"The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.",phenol-containing compound metabolic process,biological_process
66526,GO:0018960,"The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.",4-nitrophenol metabolic process,biological_process
66527,GO:0018963,"The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many com...",phthalate metabolic process,biological_process
66528,GO:0018964,"The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.",propylene metabolic process,biological_process
66529,GO:0018968,"The chemical reactions and pathways resulting in the breakdown of tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.",tetrahydrofuran catabolic process,biological_process
66530,GO:0018969,"The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.",thiocyanate metabolic process,biological_process
66531,GO:0018979,"The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.",trichloroethylene metabolic process,biological_process
66532,GO:0018982,"The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.",vanillin metabolic process,biological_process
66533,GO:0018985,Synthesis and ordering of the envelope of pronuclei.,pronuclear envelope synthesis,biological_process
66534,GO:0018989,"The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.",apolysis,biological_process
66535,GO:0018990,The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.,"ecdysis, chitin-based cuticle",biological_process
66536,GO:0018991,A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.,egg-laying behavior,biological_process
66537,GO:0018992,The determination of sex and sexual phenotype in an organism's germ line.,germ-line sex determination,biological_process
66538,GO:0018993,The determination of sex and sexual phenotypes in an organism's soma.,somatic sex determination,biological_process
66539,GO:0018995,"Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.",host cellular component,cellular_component
66540,GO:0018996,"The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.","molting cycle, collagen and cuticulin-based cuticle",biological_process
66541,GO:0019001,"Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate.",guanyl nucleotide binding,molecular_function
66542,GO:0019002,"Binding to GMP, guanosine monophosphate.",GMP binding,molecular_function
66543,GO:0019003,"Binding to GDP, guanosine 5'-diphosphate.",GDP binding,molecular_function
66544,GO:0019005,"A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).",SCF ubiquitin ligase complex,cellular_component
66545,GO:0019010,"Catalysis of the reaction: (2E,6E)-farnesoate + S-adenosyl-L-methionine = methyl (2E,6E)-farnesoate + S-adenosyl-L-homocysteine. Also converts juvenile hormone III carboxylate into juvenile hormone-III.",farnesoic acid O-methyltransferase activity,molecular_function
66546,GO:0019013,The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.,viral nucleocapsid,cellular_component
66547,GO:0019028,"The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.",viral capsid,cellular_component
66548,GO:0019029,The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.,helical viral capsid,cellular_component
66549,GO:0019030,"The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.",icosahedral viral capsid,cellular_component
66550,GO:0019031,The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.,viral envelope,cellular_component
66551,GO:0019033,"A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.",viral tegument,cellular_component
66552,GO:0019034,Specific locations and structures in the virus infected cell involved in replicating the viral genome.,viral replication complex,cellular_component
66553,GO:0019035,"A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins.",viral integration complex,cellular_component
66554,GO:0019036,Specific locations and structures in the virus infected cell involved in transcribing the viral genome.,viral transcriptional complex,cellular_component
66555,GO:0019042,"The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.",viral latency,biological_process
66556,GO:0019043,"A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.",establishment of viral latency,biological_process
66557,GO:0019044,"The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.",maintenance of viral latency,biological_process
66558,GO:0019045,Any process required for latent viral replication in a cell.,latent virus replication,biological_process
66559,GO:0019046,The process by which a virus begins to replicate following a latency replication decision (switch).,release from viral latency,biological_process
66560,GO:0019057,A process in which a symbiont alters or subverts translation of mRNA into protein in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host translation,biological_process
66561,GO:0019058,"A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.",viral life cycle,biological_process
66562,GO:0019060,The directed movement of a viral protein within the host cell.,intracellular transport of viral protein in host cell,biological_process
66563,GO:0019061,The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.,uncoating of virus,biological_process
66564,GO:0019062,The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.,virion attachment to host cell,biological_process
66565,GO:0019064,Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.,fusion of virus membrane with host plasma membrane,biological_process
66566,GO:0019065,Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.,receptor-mediated endocytosis of virus by host cell,biological_process
66567,GO:0019068,A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.,virion assembly,biological_process
66568,GO:0019069,The assembly of a virus capsid from its protein subunits.,viral capsid assembly,biological_process
66569,GO:0019070,"The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.",viral genome maturation,biological_process
66570,GO:0019072,The encapsulation of the viral genome within the capsid.,viral genome packaging,biological_process
66571,GO:0019073,The packing of viral DNA into a capsid.,viral DNA genome packaging,biological_process
66572,GO:0019074,The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid.,viral RNA genome packaging,biological_process
66573,GO:0019075,The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.,virus maturation,biological_process
66574,GO:0019076,"The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.",viral release from host cell,biological_process
66575,GO:0019079,"Any process involved directly in viral genome replication, including viral nucleotide metabolism.",viral genome replication,biological_process
66576,GO:0019080,"A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.",viral gene expression,biological_process
66577,GO:0019081,"A process by which viral mRNA is translated into viral protein, using the host cellular machinery.",viral translation,biological_process
66578,GO:0019082,Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.,viral protein processing,biological_process
66579,GO:0019083,"The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.",viral transcription,biological_process
66580,GO:0019084,"The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.",middle viral transcription,biological_process
66581,GO:0019085,"The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.",early viral transcription,biological_process
66582,GO:0019086,"The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.",late viral transcription,biological_process
66583,GO:0019087,"A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses.",symbiont-mediated transformation of host cell,biological_process
66584,GO:0019090,"The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.",mitochondrial rRNA export from mitochondrion,biological_process
66585,GO:0019091,"The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.",mitochondrial lrRNA export from mitochondrion,biological_process
66586,GO:0019092,"The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.",mitochondrial srRNA export from mitochondrion,biological_process
66587,GO:0019093,"Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.",mitochondrial RNA localization,biological_process
66588,GO:0019094,"Any process in which mRNA is transported to, or maintained in, the germ plasm.",germ plasm mRNA localization,biological_process
66589,GO:0019095,"Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the germ plasm.",germ plasm mitochondrial rRNA localization,biological_process
66590,GO:0019096,"Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the germ plasm.",germ plasm mitochondrial lrRNA localization,biological_process
66591,GO:0019097,"Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the germ plasm.",germ plasm mitochondrial srRNA localization,biological_process
66592,GO:0019098,The specific behavior of an organism that is associated with reproduction.,reproductive behavior,biological_process
66593,GO:0019099,The determination of sex and sexual phenotype in a female organism's germ line.,female germ-line sex determination,biological_process
66594,GO:0019100,The determination of sex and sexual phenotype in a male organism's germ line.,male germ-line sex determination,biological_process
66595,GO:0019101,The determination of sex and sexual phenotypes in a female organism's soma.,female somatic sex determination,biological_process
66596,GO:0019102,The determination of sex and sexual phenotypes in a male organism's soma.,male somatic sex determination,biological_process
66597,GO:0019103,"Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.",pyrimidine nucleotide binding,molecular_function
66598,GO:0019104,Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.,DNA N-glycosylase activity,molecular_function
66599,GO:0019107,Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.,myristoyltransferase activity,molecular_function
66600,GO:0019108,Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.,aryl-aldehyde dehydrogenase (NAD+) activity,molecular_function
66601,GO:0019113,Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.,limonene monooxygenase activity,molecular_function
66602,GO:0019118,Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.,phenanthrene-epoxide hydrolase activity,molecular_function
66603,GO:0019119,"Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene.","phenanthrene-9,10-epoxide hydrolase activity",molecular_function
66604,GO:0019120,Catalysis of the hydrolysis of any halide bond in substances containing halogen atoms in organic linkage.,"hydrolase activity, acting on halide bonds, in C-halide compounds",molecular_function
66605,GO:0019133,Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.,choline monooxygenase activity,molecular_function
66606,GO:0019134,Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H+.,glucosamine-1-phosphate N-acetyltransferase activity,molecular_function
66607,GO:0019135,Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.,deoxyhypusine monooxygenase activity,molecular_function
66608,GO:0019136,Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.,deoxynucleoside kinase activity,molecular_function
66609,GO:0019137,Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.,thioglucosidase activity,molecular_function
66610,GO:0019139,Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.,cytokinin dehydrogenase activity,molecular_function
66611,GO:0019140,Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.,inositol 3-kinase activity,molecular_function
66612,GO:0019141,Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.,2-dehydropantolactone reductase (B-specific) activity,molecular_function
66613,GO:0019142,Catalysis of the reaction: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H+.,2-hydroxyglutarate synthase activity,molecular_function
66614,GO:0019143,Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H2O = 3-deoxy-D-manno-octulosonate + phosphate.,3-deoxy-manno-octulosonate-8-phosphatase activity,molecular_function
66615,GO:0019144,Catalysis of the reaction: ADP-sugar + H2O = AMP + alpha-D-aldose 1-phosphate.,ADP-sugar pyrophosphatase activity,molecular_function
66616,GO:0019145,Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.,aminobutyraldehyde dehydrogenase (NAD+) activity,molecular_function
66617,GO:0019146,Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H+.,arabinose-5-phosphate isomerase activity,molecular_function
66618,GO:0019147,Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + H+ + NADH.,(R)-aminopropanol dehydrogenase activity,molecular_function
66619,GO:0019148,Catalysis of the reaction: D-cysteine + H2O = hydrogen sulfide + pyruvate + NH4+ + H+.,D-cysteine desulfhydrase activity,molecular_function
66620,GO:0019149,Catalysis of the reaction: 3-chloro-D-alanine + H2O = chloride + pyruvate + NH4+ + H+.,3-chloro-D-alanine dehydrochlorinase activity,molecular_function
66621,GO:0019150,Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate.,D-ribulokinase activity,molecular_function
66622,GO:0019151,"Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.",galactose 1-dehydrogenase activity,molecular_function
66623,GO:0019152,Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+. This reaction is catalyzed in the reverse direction.,acetoin dehydrogenase (NAD+) activity,molecular_function
66624,GO:0019153,Catalysis of the reaction: 2 glutathione + protein-disulfide = glutathione disulfide+ protein-dithiol.,protein-disulfide reductase (glutathione) activity,molecular_function
66625,GO:0019154,Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate.,glycolate dehydrogenase activity,molecular_function
66626,GO:0019155,Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.,3-(imidazol-5-yl)lactate dehydrogenase activity,molecular_function
66627,GO:0019156,"Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.",isoamylase activity,molecular_function
66628,GO:0019158,Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate.,mannokinase activity,molecular_function
66629,GO:0019159,Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = nicotinate beta-D-ribonucleotide + NH4+.,nicotinamide-nucleotide amidase activity,molecular_function
66630,GO:0019160,Catalysis of the reaction: H2O + nicotinamide mononucleotide = D-ribose 5-phosphate + H+ + nicotinamide.,NMN nucleosidase activity,molecular_function
66631,GO:0019161,"Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.",diamine:2-oxoglutarate transaminase activity,molecular_function
66632,GO:0019162,Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.,pyridoxamine:oxaloacetate transaminase activity,molecular_function
66633,GO:0019163,Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.,pyridoxamine-phosphate:2-oxoglutarate transaminase activity,molecular_function
66634,GO:0019164,Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.,pyruvate synthase activity,molecular_function
66635,GO:0019165,Catalysis of the reaction: ATP + thiamine = ADP + 2 H+ + thiamine phosphate.,thiamine kinase activity,molecular_function
66636,GO:0019166,"Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.",trans-2-enoyl-CoA reductase (NADPH) activity,molecular_function
66637,GO:0019168,"Catalysis of the reaction: a 2-(all-trans-polyprenyl)phenol + NADPH + O2 + H+ = a 3-(all-trans-polyprenyl)benzene-1,2-diol + NADP+ + H2O.",2-polyprenylphenol 6-hydroxylase activity,molecular_function
66638,GO:0019170,Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.,methylglyoxal reductase (NADH) activity,molecular_function
66639,GO:0019171,Catalysis of the reaction: a (3R)-hydroxyacyl-[acyl-carrier-protein] = a (2E)-enoyl-[acyl-carrier-protein] + H2O.,(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity,molecular_function
66640,GO:0019172,Catalysis of the reaction: methylglyoxal + H2O = D-lactate.,glyoxalase III activity,molecular_function
66641,GO:0019176,Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.,dihydroneopterin monophosphate phosphatase activity,molecular_function
66642,GO:0019177,Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.,dihydroneopterin triphosphate pyrophosphohydrolase activity,molecular_function
66643,GO:0019178,Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.,NADP phosphatase activity,molecular_function
66644,GO:0019179,"Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.","dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate transaminase activity",molecular_function
66645,GO:0019180,"Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-alpha-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate.","dTDP-4-amino-4,6-dideoxygalactose:2-oxoglutarate transaminase activity",molecular_function
66646,GO:0019181,Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.,halohydrin hydrogen-halide-lyase activity,molecular_function
66647,GO:0019182,Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane channel that opens when bound to histamine.,histamine-gated chloride channel activity,molecular_function
66648,GO:0019183,A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.,histamine-gated chloride channel complex,cellular_component
66649,GO:0019184,"The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.",nonribosomal peptide biosynthetic process,biological_process
66650,GO:0019185,A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.,snRNA-activating protein complex,cellular_component
66651,GO:0019187,"Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.","beta-1,4-mannosyltransferase activity",molecular_function
66652,GO:0019191,"Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.",cellobiose transmembrane transporter activity,molecular_function
66653,GO:0019196,"Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.",galactosamine transmembrane transporter activity,molecular_function
66654,GO:0019197,Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).,phosphoenolpyruvate-dependent sugar phosphotransferase complex,cellular_component
66655,GO:0019198,Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.,transmembrane receptor protein phosphatase activity,molecular_function
66656,GO:0019199,Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.,transmembrane receptor protein kinase activity,molecular_function
66657,GO:0019200,"Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.",carbohydrate kinase activity,molecular_function
66658,GO:0019202,"Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.",amino acid kinase activity,molecular_function
66659,GO:0019203,Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.,carbohydrate phosphatase activity,molecular_function
66660,GO:0019205,"Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.",nucleobase-containing compound kinase activity,molecular_function
66661,GO:0019206,Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.,nucleoside kinase activity,molecular_function
66662,GO:0019207,"Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",kinase regulator activity,molecular_function
66663,GO:0019208,"Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.",phosphatase regulator activity,molecular_function
66664,GO:0019209,"Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",kinase activator activity,molecular_function
66665,GO:0019210,"Binds to and stops, prevents or reduces the activity of a kinase.",kinase inhibitor activity,molecular_function
66666,GO:0019211,Binds to and increases the activity of a phosphatase.,phosphatase activator activity,molecular_function
66667,GO:0019212,"Binds to and stops, prevents or reduces the activity of a phosphatase.",phosphatase inhibitor activity,molecular_function
66668,GO:0019213,Catalysis of the hydrolysis of an acetyl group from a substrate molecule.,deacetylase activity,molecular_function
66669,GO:0019215,"Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.",intermediate filament binding,molecular_function
66670,GO:0019216,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.",regulation of lipid metabolic process,biological_process
66671,GO:0019217,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.",regulation of fatty acid metabolic process,biological_process
66672,GO:0019218,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.",regulation of steroid metabolic process,biological_process
66673,GO:0019219,"Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.",regulation of nucleobase-containing compound metabolic process,biological_process
66674,GO:0019221,"The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",cytokine-mediated signaling pathway,biological_process
66675,GO:0019222,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.",regulation of metabolic process,biological_process
66676,GO:0019226,The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.,transmission of nerve impulse,biological_process
66677,GO:0019227,"The propagation of an action potential along an axon, away from the soma.",neuronal action potential propagation,biological_process
66678,GO:0019228,An action potential that occurs in a neuron.,neuronal action potential,biological_process
66679,GO:0019229,"Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.",regulation of vasoconstriction,biological_process
66680,GO:0019230,"The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.",proprioception,biological_process
66681,GO:0019231,The perception of the orientation of different parts of the body with respect to one another.,perception of static position,biological_process
66682,GO:0019232,The series of events by which an organism senses the speed and direction of movement of the body and its parts.,perception of rate of movement,biological_process
66683,GO:0019233,"The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system.",sensory perception of pain,biological_process
66684,GO:0019234,"The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.",sensory perception of fast pain,biological_process
66685,GO:0019235,"The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.",sensory perception of slow pain,biological_process
66686,GO:0019236,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.",response to pheromone,biological_process
66687,GO:0019237,"Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.",centromeric DNA binding,molecular_function
66688,GO:0019238,"Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.",cyclohydrolase activity,molecular_function
66689,GO:0019239,"Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH4+/NH2R).",deaminase activity,molecular_function
66690,GO:0019240,"The chemical reactions and pathways resulting in the formation of L-citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.",L-citrulline biosynthetic process,biological_process
66691,GO:0019241,The chemical reactions and pathways resulting in the breakdown of L-citrulline.,L-citrulline catabolic process,biological_process
66692,GO:0019242,"The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.",methylglyoxal biosynthetic process,biological_process
66693,GO:0019244,The anaerobic chemical reactions and pathways resulting in the breakdown of pyruvate into D-lactate or L-lactate.,pyruvate fermentation to lactate,biological_process
66694,GO:0019247,"Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.",lactate racemization,biological_process
66695,GO:0019249,"The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.",lactate biosynthetic process,biological_process
66696,GO:0019252,"The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.",starch biosynthetic process,biological_process
66697,GO:0019253,"The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is conver...",reductive pentose-phosphate cycle,biological_process
66698,GO:0019254,"The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.","carnitine metabolic process, CoA-linked",biological_process
66699,GO:0019255,"The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.",glucose 1-phosphate metabolic process,biological_process
66700,GO:0019256,"The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.",acrylonitrile catabolic process,biological_process
66701,GO:0019258,"The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.",4-nitrotoluene catabolic process,biological_process
66702,GO:0019260,"The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.","1,2-dichloroethane catabolic process",biological_process
66703,GO:0019261,"The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.","1,4-dichlorobenzene catabolic process",biological_process
66704,GO:0019262,"The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.",N-acetylneuraminate catabolic process,biological_process
66705,GO:0019263,"The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.",adamantanone catabolic process,biological_process
66706,GO:0019270,"The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.",aerobactin biosynthetic process,biological_process
66707,GO:0019271,"The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.",aerobactin transport,biological_process
66708,GO:0019276,"The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylgalactosamine metabolic process,biological_process
66709,GO:0019277,"The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.",UDP-N-acetylgalactosamine biosynthetic process,biological_process
66710,GO:0019287,"The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.","isopentenyl diphosphate biosynthetic process, mevalonate pathway",biological_process
66711,GO:0019288,"The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the methylerythritol phosphate pathway, also known as the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates, including methylerythritol 4-phosphate.","isopentenyl diphosphate biosynthetic process, methylerythritol phosphate pathway",biological_process
66712,GO:0019289,"The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.",rhizobactin 1021 biosynthetic process,biological_process
66713,GO:0019290,"The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.",siderophore biosynthetic process,biological_process
66714,GO:0019294,"The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.",keto-3-deoxy-D-manno-octulosonic acid biosynthetic process,biological_process
66715,GO:0019295,"The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.",coenzyme M biosynthetic process,biological_process
66716,GO:0019298,"The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.",coenzyme B biosynthetic process,biological_process
66717,GO:0019300,"The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.",rhamnose biosynthetic process,biological_process
66718,GO:0019301,"The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.",rhamnose catabolic process,biological_process
66719,GO:0019302,"The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).",D-ribose biosynthetic process,biological_process
66720,GO:0019303,The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).,D-ribose catabolic process,biological_process
66721,GO:0019305,"The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.",dTDP-rhamnose biosynthetic process,biological_process
66722,GO:0019306,"The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.",GDP-D-rhamnose biosynthetic process,biological_process
66723,GO:0019307,"The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.",mannose biosynthetic process,biological_process
66724,GO:0019308,"The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.",dTDP-mannose biosynthetic process,biological_process
66725,GO:0019309,"The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.",mannose catabolic process,biological_process
66726,GO:0019310,"The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.",inositol catabolic process,biological_process
66727,GO:0019315,"The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.",D-allose biosynthetic process,biological_process
66728,GO:0019316,"The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.",D-allose catabolic process,biological_process
66729,GO:0019318,"The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.",hexose metabolic process,biological_process
66730,GO:0019319,"The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.",hexose biosynthetic process,biological_process
66731,GO:0019320,"The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.",hexose catabolic process,biological_process
66732,GO:0019321,"The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.",pentose metabolic process,biological_process
66733,GO:0019322,"The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.",pentose biosynthetic process,biological_process
66734,GO:0019323,"The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.",pentose catabolic process,biological_process
66735,GO:0019324,"The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.",L-lyxose metabolic process,biological_process
66736,GO:0019327,The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate.,lead sulfide oxidation,biological_process
66737,GO:0019329,"The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.",ammonia oxidation,biological_process
66738,GO:0019331,"The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. Hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.","anaerobic respiration, using ammonium as electron donor",biological_process
66739,GO:0019332,"The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.","aerobic respiration, using nitrite as electron donor",biological_process
66740,GO:0019333,"The reduction of nitrate to dinitrogen by four reduction reactions: nitrate reduced to nitrite, then to nitric oxide, then to nitrous oxide, and finally to dinitrogen.",denitrification pathway,biological_process
66741,GO:0019334,"The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.",p-cymene catabolic process,biological_process
66742,GO:0019335,"The chemical reactions and pathways resulting in the breakdown of methylquinoline, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.",methylquinoline catabolic process,biological_process
66743,GO:0019336,"The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.",phenol-containing compound catabolic process,biological_process
66744,GO:0019337,"The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.",tetrachloroethylene catabolic process,biological_process
66745,GO:0019338,"The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.",pentachlorophenol catabolic process,biological_process
66746,GO:0019339,"The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.",parathion catabolic process,biological_process
66747,GO:0019340,"The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.",dibenzofuran catabolic process,biological_process
66748,GO:0019341,"The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.",dibenzo-p-dioxin catabolic process,biological_process
66749,GO:0019342,"The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.",trypanothione biosynthetic process,biological_process
66750,GO:0019344,"The chemical reactions and pathways resulting in the formation of L-cysteine, 2-amino-3-mercaptopropanoic acid.",L-cysteine biosynthetic process,biological_process
66751,GO:0019346,"The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.",transsulfuration,biological_process
66752,GO:0019347,"The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.",GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process,biological_process
66753,GO:0019350,"The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.",teichoic acid biosynthetic process,biological_process
66754,GO:0019354,"The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.",siroheme biosynthetic process,biological_process
66755,GO:0019357,"The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).",nicotinate nucleotide biosynthetic process,biological_process
66756,GO:0019358,The generation of nicotinate nucleotide without de novo synthesis.,nicotinate nucleotide salvage,biological_process
66757,GO:0019359,"The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.",nicotinamide nucleotide biosynthetic process,biological_process
66758,GO:0019361,"The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.",2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process,biological_process
66759,GO:0019363,"The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.",pyridine nucleotide biosynthetic process,biological_process
66760,GO:0019364,"The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.",pyridine nucleotide catabolic process,biological_process
66761,GO:0019365,"Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.",pyridine nucleotide salvage,biological_process
66762,GO:0019367,Elongation of a saturated fatty acid chain.,"fatty acid elongation, saturated fatty acid",biological_process
66763,GO:0019368,Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.,"fatty acid elongation, unsaturated fatty acid",biological_process
66764,GO:0019369,"The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.",arachidonate metabolic process,biological_process
66765,GO:0019370,"The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.",leukotriene biosynthetic process,biological_process
66766,GO:0019371,"The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.",cyclooxygenase pathway,biological_process
66767,GO:0019372,"The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.",lipoxygenase pathway,biological_process
66768,GO:0019373,The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.,epoxygenase P450 pathway,biological_process
66769,GO:0019374,"The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.",galactolipid metabolic process,biological_process
66770,GO:0019375,"The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.",galactolipid biosynthetic process,biological_process
66771,GO:0019376,"The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.",galactolipid catabolic process,biological_process
66772,GO:0019377,"The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).",glycolipid catabolic process,biological_process
66773,GO:0019380,"The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.",3-phenylpropionate catabolic process,biological_process
66774,GO:0019381,"The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.",atrazine catabolic process,biological_process
66775,GO:0019382,"The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.",carbon tetrachloride catabolic process,biological_process
66776,GO:0019383,"The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.",(+)-camphor catabolic process,biological_process
66777,GO:0019384,"The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.",caprolactam catabolic process,biological_process
66778,GO:0019385,"The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.","methanogenesis, from acetate",biological_process
66779,GO:0019386,"The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).","methanogenesis, from carbon dioxide",biological_process
66780,GO:0019387,"The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.","methanogenesis, from methanol",biological_process
66781,GO:0019388,"The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.",galactose catabolic process,biological_process
66782,GO:0019391,"The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.",glucuronoside catabolic process,biological_process
66783,GO:0019395,"The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.",fatty acid oxidation,biological_process
66784,GO:0019396,"The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).",gallate catabolic process,biological_process
66785,GO:0019399,The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.,cyclohexanol oxidation,biological_process
66786,GO:0019401,"The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.",alditol biosynthetic process,biological_process
66787,GO:0019402,"The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.",galactitol metabolic process,biological_process
66788,GO:0019403,"The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.",galactitol biosynthetic process,biological_process
66789,GO:0019404,"The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.",galactitol catabolic process,biological_process
66790,GO:0019405,"The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.",alditol catabolic process,biological_process
66791,GO:0019406,"The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.",hexitol biosynthetic process,biological_process
66792,GO:0019407,"The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.",hexitol catabolic process,biological_process
66793,GO:0019409,"The metabolic process in which ammonia (NH4+) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.","aerobic respiration, using ammonia as electron donor",biological_process
66794,GO:0019410,The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.,"aerobic respiration, using carbon monoxide as electron donor",biological_process
66795,GO:0019411,"The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.","aerobic respiration, using ferrous ions as electron donor",biological_process
66796,GO:0019412,"The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.","aerobic respiration, using hydrogen as electron donor",biological_process
66797,GO:0019413,"The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.",acetate biosynthetic process,biological_process
66798,GO:0019414,"An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.","aerobic respiration, using sulfur or sulfate as electron donor",biological_process
66799,GO:0019416,"The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.",thiosulfate oxidation,biological_process
66800,GO:0019417,The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.,sulfur oxidation,biological_process
66801,GO:0019418,The chemical reactions and pathways resulting in the conversion of sufide to sulfite or sulfate.,sulfide oxidation,biological_process
66802,GO:0019420,"The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.",dissimilatory sulfate reduction,biological_process
66803,GO:0019422,The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process.,disproportionation of elemental sulfur,biological_process
66804,GO:0019428,"The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.",allantoin biosynthetic process,biological_process
66805,GO:0019429,"The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.",fluorene catabolic process,biological_process
66806,GO:0019430,"Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).",removal of superoxide radicals,biological_process
66807,GO:0019432,"The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.",triglyceride biosynthetic process,biological_process
66808,GO:0019433,"The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.",triglyceride catabolic process,biological_process
66809,GO:0019435,"The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.",sophorosyloxydocosanoate biosynthetic process,biological_process
66810,GO:0019436,"The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.",sophorosyloxydocosanoate catabolic process,biological_process
66811,GO:0019448,The chemical reactions and pathways resulting in the breakdown of L-cysteine.,L-cysteine catabolic process,biological_process
66812,GO:0019464,"The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.",glycine decarboxylation via glycine cleavage system,biological_process
66813,GO:0019470,The chemical reactions and pathways resulting in the breakdown of trans-4-hydroxy-L-proline.,trans-4-hydroxy-L-proline catabolic process,biological_process
66814,GO:0019475,"The chemical reactions and pathways resulting in the breakdown of L-lysine into acetyl-CoA and butanoate. Acetyl-CoA can be further converted into acetate, releasing one ATP molecule.",L-lysine fermentation,biological_process
66815,GO:0019477,The chemical reactions and pathways resulting in the breakdown of L-lysine.,L-lysine catabolic process,biological_process
66816,GO:0019478,"The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.",D-amino acid catabolic process,biological_process
66817,GO:0019483,"The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.",beta-alanine biosynthetic process,biological_process
66818,GO:0019484,The chemical reactions and pathways resulting in the breakdown of beta-alanine.,beta-alanine catabolic process,biological_process
66819,GO:0019487,"The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.",anaerobic acetylene catabolic process,biological_process
66820,GO:0019490,"The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.",2-aminobenzenesulfonate desulfonation,biological_process
66821,GO:0019491,"The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.",ectoine biosynthetic process,biological_process
66822,GO:0019497,"The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.",hexachlorocyclohexane metabolic process,biological_process
66823,GO:0019498,The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA.,n-octane oxidation,biological_process
66824,GO:0019499,"The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.",cyanide metabolic process,biological_process
66825,GO:0019500,"The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.",cyanide catabolic process,biological_process
66826,GO:0019501,"The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.",arsonoacetate catabolic process,biological_process
66827,GO:0019504,The chemical reactions and pathways resulting in the breakdown of L-proline betaine (stachydrine).,L-proline betaine catabolic process,biological_process
66828,GO:0019505,"The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.",resorcinol metabolic process,biological_process
66829,GO:0019506,"The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.",phenylmercury acetate catabolic process,biological_process
66830,GO:0019511,The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.,peptidyl-proline hydroxylation,biological_process
66831,GO:0019519,"The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.",pentitol metabolic process,biological_process
66832,GO:0019521,"The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.",D-gluconate metabolic process,biological_process
66833,GO:0019524,"The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.",keto-D-gluconate catabolic process,biological_process
66834,GO:0019526,"The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.",pentitol biosynthetic process,biological_process
66835,GO:0019527,"The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.",pentitol catabolic process,biological_process
66836,GO:0019529,"The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.",taurine catabolic process,biological_process
66837,GO:0019530,"The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.",taurine metabolic process,biological_process
66838,GO:0019531,"Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.",oxalate transmembrane transporter activity,molecular_function
66839,GO:0019532,"The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.",oxalate transport,biological_process
66840,GO:0019533,"The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.",cellobiose transport,biological_process
66841,GO:0019534,Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.,toxin transmembrane transporter activity,molecular_function
66842,GO:0019535,Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other.,ferric-vibriobactin transmembrane transporter activity,molecular_function
66843,GO:0019536,"The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.",vibriobactin metabolic process,biological_process
66844,GO:0019537,"The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.",vibriobactin biosynthetic process,biological_process
66845,GO:0019538,The chemical reactions and pathways involving a protein. Includes protein modification.,protein metabolic process,biological_process
66846,GO:0019539,"The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).",hydroxymate-containing siderophore biosynthetic process,biological_process
66847,GO:0019540,"The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+).",catechol-containing siderophore biosynthetic process,biological_process
66848,GO:0019541,"The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.",propionate metabolic process,biological_process
66849,GO:0019542,"The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.",propionate biosynthetic process,biological_process
66850,GO:0019543,"The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.",propionate catabolic process,biological_process
66851,GO:0019563,"The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.",glycerol catabolic process,biological_process
66852,GO:0019566,"The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.",arabinose metabolic process,biological_process
66853,GO:0019567,"The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.",arabinose biosynthetic process,biological_process
66854,GO:0019568,"The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.",arabinose catabolic process,biological_process
66855,GO:0019571,"The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.",D-arabinose catabolic process,biological_process
66856,GO:0019572,"The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.",L-arabinose catabolic process,biological_process
66857,GO:0019578,"The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.",aldaric acid biosynthetic process,biological_process
66858,GO:0019579,"The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.",aldaric acid catabolic process,biological_process
66859,GO:0019580,"The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.",galactarate metabolic process,biological_process
66860,GO:0019585,"The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.",glucuronate metabolic process,biological_process
66861,GO:0019588,"The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.",anaerobic glycerol catabolic process,biological_process
66862,GO:0019592,"The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.",mannitol catabolic process,biological_process
66863,GO:0019593,"The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.",mannitol biosynthetic process,biological_process
66864,GO:0019594,"The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.",mannitol metabolic process,biological_process
66865,GO:0019595,The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.,non-phosphorylated glucose catabolic process,biological_process
66866,GO:0019596,"The chemical reactions and pathways resulting in the breakdown of (R)-mandelate, the anion of (R)-mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.",(R)-mandelate catabolic process,biological_process
66867,GO:0019599,"The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.",(R)-4-hydroxymandelate catabolic process,biological_process
66868,GO:0019605,"The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.",butyrate metabolic process,biological_process
66869,GO:0019606,"The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.",2-oxobutyrate catabolic process,biological_process
66870,GO:0019607,"The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.",phenylethylamine catabolic process,biological_process
66871,GO:0019608,"The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.",nicotine catabolic process,biological_process
66872,GO:0019610,"The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.",3-hydroxyphenylacetate catabolic process,biological_process
66873,GO:0019612,"The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.",4-toluenecarboxylate catabolic process,biological_process
66874,GO:0019614,The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.,catechol-containing compound catabolic process,biological_process
66875,GO:0019615,"The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.","catechol catabolic process, ortho-cleavage",biological_process
66876,GO:0019616,"The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.","catechol catabolic process, meta-cleavage",biological_process
66877,GO:0019617,"The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.","protocatechuate catabolic process, meta-cleavage",biological_process
66878,GO:0019618,"The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.","protocatechuate catabolic process, ortho-cleavage",biological_process
66879,GO:0019619,"The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.","3,4-dihydroxybenzoate catabolic process",biological_process
66880,GO:0019622,"The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.",3-(3-hydroxy)phenylpropionate catabolic process,biological_process
66881,GO:0019626,The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid catabolic process,biological_process
66882,GO:0019627,"The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.",urea metabolic process,biological_process
66883,GO:0019628,"The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.",urate catabolic process,biological_process
66884,GO:0019631,"The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.",quinate catabolic process,biological_process
66885,GO:0019632,"The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.",shikimate metabolic process,biological_process
66886,GO:0019633,"The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.",shikimate catabolic process,biological_process
66887,GO:0019634,"The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.",organic phosphonate metabolic process,biological_process
66888,GO:0019635,"The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.",2-aminoethylphosphonate catabolic process,biological_process
66889,GO:0019636,"The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.",phosphonoacetate metabolic process,biological_process
66890,GO:0019637,"The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.",organophosphate metabolic process,biological_process
66891,GO:0019639,"The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.",6-hydroxycineole catabolic process,biological_process
66892,GO:0019643,"A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate re...",reductive tricarboxylic acid cycle,biological_process
66893,GO:0019645,A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.,anaerobic electron transport chain,biological_process
66894,GO:0019646,A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.,aerobic electron transport chain,biological_process
66895,GO:0019649,The pathways in which formaldehyde is processed and used as a carbon source for the cell.,formaldehyde assimilation,biological_process
66896,GO:0019653,"The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding acetate and CO2.",purine fermentation,biological_process
66897,GO:0019654,"The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.",pyruvate fermentation to acetate,biological_process
66898,GO:0019655,The anaerobic chemical reactions and pathways resulting in the breakdown of pyruvate into ethanol and carbon dioxide (CO2).,pyruvate fermentation to ethanol,biological_process
66899,GO:0019657,"The anaerobic chemical reactions and pathways resulting in the breakdown of pyruvate into to propionate, an alternative to the acrylate pathway to produce propionate.",pyruvate fermentation to propionate,biological_process
66900,GO:0019658,"The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.",bifid shunt,biological_process
66901,GO:0019660,"The fermentation process resulting in the oxygen-independent conversion of pyruvate to reduced end products (e.g., lactate, ethanol, and acetate), accompanied by the concomitant oxidation of NADH to NAD.",pyruvate fermentation,biological_process
66902,GO:0019664,"The anaerobic chemical reactions and pathways resulting in the breakdown of phosphoenolpyruvate into ethanol, lactate, formate, succinate, and acetate.",mixed acid fermentation,biological_process
66903,GO:0019665,"The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids to ammonia, CO2, H2, acetate and short chain fatty acids, under anoxic conditions.",amino acid fermentation,biological_process
66904,GO:0019667,"The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding acetylCoA. AcetylCoA can be further converted to ATP.",L-alanine fermentation,biological_process
66905,GO:0019668,"The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.",anaerobic catabolism of pairs of amino acids,biological_process
66906,GO:0019669,"The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.",glycine fermentation,biological_process
66907,GO:0019673,"The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.",GDP-mannose metabolic process,biological_process
66908,GO:0019674,"The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD+), a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.",NAD+ metabolic process,biological_process
66909,GO:0019676,"The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.",ammonia assimilation cycle,biological_process
66910,GO:0019677,"The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide (NAD+), a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.",NAD+ catabolic process,biological_process
66911,GO:0019680,"The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.",L-methylmalonyl-CoA biosynthetic process,biological_process
66912,GO:0019681,The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.,acetyl-CoA assimilation pathway,biological_process
66913,GO:0019682,"The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.",glyceraldehyde-3-phosphate metabolic process,biological_process
66914,GO:0019683,"The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.",glyceraldehyde-3-phosphate catabolic process,biological_process
66915,GO:0019684,"The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two ...","photosynthesis, light reaction",biological_process
66916,GO:0019685,A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.,"photosynthesis, dark reaction",biological_process
66917,GO:0019686,The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.,purine nucleoside interconversion,biological_process
66918,GO:0019688,The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.,purine deoxyribonucleoside interconversion,biological_process
66919,GO:0019689,The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.,pyrimidine nucleoside interconversion,biological_process
66920,GO:0019690,The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.,pyrimidine deoxyribonucleoside interconversion,biological_process
66921,GO:0019693,"The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.",ribose phosphate metabolic process,biological_process
66922,GO:0019694,"The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.",alkanesulfonate metabolic process,biological_process
66923,GO:0019695,"The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.",choline metabolic process,biological_process
66924,GO:0019697,The chemical reactions and pathways resulting in the breakdown of xylitol to form xylulose 5-phosphate.,xylitol catabolic process to D-xylulose 5-phosphate,biological_process
66925,GO:0019698,"The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.",D-galacturonate catabolic process,biological_process
66926,GO:0019700,"The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.",organic phosphonate catabolic process,biological_process
66927,GO:0019702,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.,protein arginine N5-methyltransferase activity,molecular_function
66928,GO:0019705,"Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].",protein-cysteine S-myristoyltransferase activity,molecular_function
66929,GO:0019706,"Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",protein-cysteine S-palmitoyltransferase activity,molecular_function
66930,GO:0019707,Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.,protein-cysteine S-acyltransferase activity,molecular_function
66931,GO:0019720,"The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.",Mo-molybdopterin cofactor metabolic process,biological_process
66932,GO:0019722,Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.,calcium-mediated signaling,biological_process
66933,GO:0019724,"Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.",B cell mediated immunity,biological_process
66934,GO:0019725,Any process involved in the maintenance of an internal steady state at the level of the cell.,cellular homeostasis,biological_process
66935,GO:0019730,An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.,antimicrobial humoral response,biological_process
66936,GO:0019731,An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.,antibacterial humoral response,biological_process
66937,GO:0019732,An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.,antifungal humoral response,biological_process
66938,GO:0019740,"A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, an...",nitrogen utilization,biological_process
66939,GO:0019741,"The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.",pentacyclic triterpenoid catabolic process,biological_process
66940,GO:0019742,"The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.",pentacyclic triterpenoid metabolic process,biological_process
66941,GO:0019743,"The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.",hopanoid catabolic process,biological_process
66942,GO:0019745,"The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.",pentacyclic triterpenoid biosynthetic process,biological_process
66943,GO:0019746,"The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.",hopanoid biosynthetic process,biological_process
66944,GO:0019747,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.",regulation of isoprenoid metabolic process,biological_process
66945,GO:0019748,"The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.",secondary metabolic process,biological_process
66946,GO:0019749,"The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.","cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte",biological_process
66947,GO:0019750,"Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.",chloroplast localization,biological_process
66948,GO:0019751,"The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.",polyol metabolic process,biological_process
66949,GO:0019752,"The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).",carboxylic acid metabolic process,biological_process
66950,GO:0019755,"The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",one-carbon compound transport,biological_process
66951,GO:0019756,"The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.",cyanogenic glycoside biosynthetic process,biological_process
66952,GO:0019760,"The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.",glucosinolate metabolic process,biological_process
66953,GO:0019761,"The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.",glucosinolate biosynthetic process,biological_process
66954,GO:0019762,"The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.",glucosinolate catabolic process,biological_process
66955,GO:0019763,Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,immunoglobulin receptor activity,molecular_function
66956,GO:0019766,"Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",IgA receptor activity,molecular_function
66957,GO:0019767,"Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",IgE receptor activity,molecular_function
66958,GO:0019768,"Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",high-affinity IgE receptor activity,molecular_function
66959,GO:0019769,"Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",low-affinity IgE receptor activity,molecular_function
66960,GO:0019770,"Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",IgG receptor activity,molecular_function
66961,GO:0019771,"Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",high-affinity IgG receptor activity,molecular_function
66962,GO:0019772,"Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",low-affinity IgG receptor activity,molecular_function
66963,GO:0019773,The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.,"proteasome core complex, alpha-subunit complex",cellular_component
66964,GO:0019774,The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.,"proteasome core complex, beta-subunit complex",cellular_component
66965,GO:0019775,"Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.",FAT10 transferase activity,molecular_function
66966,GO:0019776,Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 family modifier to phosphatidylethanolamine or phosphatidylserine on a membrane.,Atg8-family ligase activity,molecular_function
66967,GO:0019777,"Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.",Atg12 transferase activity,molecular_function
66968,GO:0019778,"Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.",Atg12 activating enzyme activity,molecular_function
66969,GO:0019779,"Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.",Atg8 activating enzyme activity,molecular_function
66970,GO:0019780,"Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.",FAT10 activating enzyme activity,molecular_function
66971,GO:0019781,Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.,NEDD8 activating enzyme activity,molecular_function
66972,GO:0019782,"Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.",ISG15 activating enzyme activity,molecular_function
66973,GO:0019783,"An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.",ubiquitin-like protein peptidase activity,molecular_function
66974,GO:0019784,An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.,deNEDDylase activity,molecular_function
66975,GO:0019785,A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.,ISG15-specific peptidase activity,molecular_function
66976,GO:0019786,"Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.",protein-phosphatidylethanolamide deconjugating activity,molecular_function
66977,GO:0019787,"Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.",ubiquitin-like protein transferase activity,molecular_function
66978,GO:0019788,"Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.",NEDD8 transferase activity,molecular_function
66979,GO:0019789,"Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.",SUMO transferase activity,molecular_function
66980,GO:0019797,Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.,procollagen-proline 3-dioxygenase activity,molecular_function
66981,GO:0019798,Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.,procollagen-proline dioxygenase activity,molecular_function
66982,GO:0019799,Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine. In most organisms it acetylates L-lysine at position 40 of alpha- tubulin.,tubulin N-acetyltransferase activity,molecular_function
66983,GO:0019805,"The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.",quinolinate biosynthetic process,biological_process
66984,GO:0019806,"Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.",bromide peroxidase activity,molecular_function
66985,GO:0019807,Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.,aspartoacylase activity,molecular_function
66986,GO:0019808,"Binding to a polyamine, an organic compound containing two or more amino groups.",polyamine binding,molecular_function
66987,GO:0019809,"Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",spermidine binding,molecular_function
66988,GO:0019810,"Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.",putrescine binding,molecular_function
66989,GO:0019811,"Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.",cocaine binding,molecular_function
66990,GO:0019812,"A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex...",type I site-specific deoxyribonuclease complex,cellular_component
66991,GO:0019813,"A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that m...",type III site-specific deoxyribonuclease complex,cellular_component
66992,GO:0019814,"A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",immunoglobulin complex,cellular_component
66993,GO:0019815,"An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",B cell receptor complex,cellular_component
66994,GO:0019817,The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.,vesicle fusion with peroxisome,biological_process
66995,GO:0019819,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.",P1 peroxisome,cellular_component
66996,GO:0019820,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.",P2 peroxisome,cellular_component
66997,GO:0019821,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.",P3 peroxisome,cellular_component
66998,GO:0019822,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.",P4 peroxisome,cellular_component
66999,GO:0019823,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.",P5 peroxisome,cellular_component
67000,GO:0019824,"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.",P6 peroxisome,cellular_component
67001,GO:0019825,Binding to oxygen (O2).,oxygen binding,molecular_function
67002,GO:0019826,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).",oxygen sensor activity,molecular_function
67003,GO:0019827,The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.,stem cell population maintenance,biological_process
67004,GO:0019828,"Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases.",aspartic-type endopeptidase inhibitor activity,molecular_function
67005,GO:0019829,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).,ATPase-coupled monoatomic cation transmembrane transporter activity,molecular_function
67006,GO:0019833,"Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees Celsius) to protect the organism from damage by intracellular ice formation. This process is commonly found in certain bacteria, such as Pseudomonas syringae, and plays roles in environmental adaptation and plant pathogenesis.",ice nucleation activity,molecular_function
67007,GO:0019834,"Binds to and stops, prevents or reduces the activity of phospholipase A2.",phospholipase A2 inhibitor activity,molecular_function
67008,GO:0019835,The rupture of cell membranes and the loss of cytoplasm.,cytolysis,biological_process
67009,GO:0019836,"The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated hemolysis of host erythrocyte,biological_process
67010,GO:0019838,"Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.",growth factor binding,molecular_function
67011,GO:0019840,"Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.",isoprenoid binding,molecular_function
67012,GO:0019841,"Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.",retinol binding,molecular_function
67013,GO:0019842,"Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",vitamin binding,molecular_function
67014,GO:0019843,Binding to a ribosomal RNA.,rRNA binding,molecular_function
67015,GO:0019852,"The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.",L-ascorbic acid metabolic process,biological_process
67016,GO:0019853,"The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.",L-ascorbic acid biosynthetic process,biological_process
67017,GO:0019854,"The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.",L-ascorbic acid catabolic process,biological_process
67018,GO:0019855,"Binds to and stops, prevents, or reduces the activity of a calcium channel.",calcium channel inhibitor activity,molecular_function
67019,GO:0019856,"The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.",pyrimidine nucleobase biosynthetic process,biological_process
67020,GO:0019858,"The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.",cytosine metabolic process,biological_process
67021,GO:0019859,"The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.",thymine metabolic process,biological_process
67022,GO:0019860,"The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.",uracil metabolic process,biological_process
67023,GO:0019862,Binding to an immunoglobulin of an IgA isotype.,IgA binding,molecular_function
67024,GO:0019863,Binding to an immunoglobulin of the IgE isotype.,IgE binding,molecular_function
67025,GO:0019864,Binding to an immunoglobulin of an IgG isotype.,IgG binding,molecular_function
67026,GO:0019865,Binding to an immunoglobulin.,immunoglobulin binding,molecular_function
67027,GO:0019866,"The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.",organelle inner membrane,cellular_component
67028,GO:0019867,The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.,outer membrane,cellular_component
67029,GO:0019869,"Binds to and stops, prevents, or reduces the activity of a chloride channel.",chloride channel inhibitor activity,molecular_function
67030,GO:0019870,"Binds to and stops, prevents, or reduces the activity of a potassium channel.",potassium channel inhibitor activity,molecular_function
67031,GO:0019871,"Binds to and stops, prevents, or reduces the activity of a sodium channel.",sodium channel inhibitor activity,molecular_function
67032,GO:0019872,"The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.",streptomycin biosynthetic process,biological_process
67033,GO:0019874,"Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate.",6-aminohexanoate-cyclic-dimer hydrolase activity,molecular_function
67034,GO:0019875,Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.,6-aminohexanoate-dimer hydrolase activity,molecular_function
67035,GO:0019876,"The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.",nylon catabolic process,biological_process
67036,GO:0019882,The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.,antigen processing and presentation,biological_process
67037,GO:0019883,The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.,antigen processing and presentation of endogenous antigen,biological_process
67038,GO:0019884,The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.,antigen processing and presentation of exogenous antigen,biological_process
67039,GO:0019885,"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.",antigen processing and presentation of endogenous peptide antigen via MHC class I,biological_process
67040,GO:0019886,"The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.",antigen processing and presentation of exogenous peptide antigen via MHC class II,biological_process
67041,GO:0019887,"Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.",protein kinase regulator activity,molecular_function
67042,GO:0019888,Binds to and modulates the activity of a protein phosphatase.,protein phosphatase regulator activity,molecular_function
67043,GO:0019889,"The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.",pteridine metabolic process,biological_process
67044,GO:0019894,"Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.",kinesin binding,molecular_function
67045,GO:0019896,The directed movement of mitochondria along microtubules in nerve cell axons.,axonal transport of mitochondrion,biological_process
67046,GO:0019897,"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of plasma membrane,cellular_component
67047,GO:0019898,"The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of membrane,cellular_component
67048,GO:0019899,"Binding to an enzyme, a protein with catalytic activity.",enzyme binding,molecular_function
67049,GO:0019900,"Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.",kinase binding,molecular_function
67050,GO:0019901,"Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.",protein kinase binding,molecular_function
67051,GO:0019902,Binding to a phosphatase.,phosphatase binding,molecular_function
67052,GO:0019903,Binding to a protein phosphatase.,protein phosphatase binding,molecular_function
67053,GO:0019904,Binding to a specific domain of a protein.,protein domain specific binding,molecular_function
67054,GO:0019905,"Binding to a syntaxin, a SNAP receptor involved in the docking of vesicles.",syntaxin binding,molecular_function
67055,GO:0019908,Cyclin-dependent protein kinase (CDK) complex found in the nucleus.,nuclear cyclin-dependent protein kinase holoenzyme complex,cellular_component
67056,GO:0019910,A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.,mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex,cellular_component
67057,GO:0019911,The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.,structural constituent of myelin sheath,molecular_function
67058,GO:0019914,Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.,cyclin-dependent protein kinase regulator activity,molecular_function
67059,GO:0019915,"The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.",lipid storage,biological_process
67060,GO:0019918,"The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.","peptidyl-arginine methylation, to symmetrical-dimethyl arginine",biological_process
67061,GO:0019919,"The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.","peptidyl-arginine methylation, to asymmetrical-dimethyl arginine",biological_process
67062,GO:0019941,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.",modification-dependent protein catabolic process,biological_process
67063,GO:0019948,"Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.",SUMO activating enzyme activity,molecular_function
67064,GO:0019953,"A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).",sexual reproduction,biological_process
67065,GO:0019954,"A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells.",asexual reproduction,biological_process
67066,GO:0019955,"Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.",cytokine binding,molecular_function
67067,GO:0019956,"Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are...",chemokine binding,molecular_function
67068,GO:0019957,Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.,C-C chemokine binding,molecular_function
67069,GO:0019958,Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.,C-X-C chemokine binding,molecular_function
67070,GO:0019959,Binding to interleukin-8.,interleukin-8 binding,molecular_function
67071,GO:0019960,Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.,C-X3-C chemokine binding,molecular_function
67072,GO:0019961,"Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.",interferon binding,molecular_function
67073,GO:0019962,"Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.",type I interferon binding,molecular_function
67074,GO:0019964,"Binding to type II interferon, also known as interferon-gamma.",type II interferon binding,molecular_function
67075,GO:0019966,Binding to interleukin-1.,interleukin-1 binding,molecular_function
67076,GO:0019969,Binding to interleukin-10.,interleukin-10 binding,molecular_function
67077,GO:0019970,Binding to interleukin-11.,interleukin-11 binding,molecular_function
67078,GO:0019972,Binding to interleukin-12.,interleukin-12 binding,molecular_function
67079,GO:0019973,Binding to interleukin-13.,interleukin-13 binding,molecular_function
67080,GO:0019975,Binding to a member of the interleukin-17 family of cytokines.,interleukin-17 binding,molecular_function
67081,GO:0019976,Binding to interleukin-2.,interleukin-2 binding,molecular_function
67082,GO:0019977,Binding to interleukin-21.,interleukin-21 binding,molecular_function
67083,GO:0019978,Binding to interleukin-3.,interleukin-3 binding,molecular_function
67084,GO:0019979,Binding to interleukin-4.,interleukin-4 binding,molecular_function
67085,GO:0019980,Binding to interleukin-5.,interleukin-5 binding,molecular_function
67086,GO:0019981,Binding to interleukin-6.,interleukin-6 binding,molecular_function
67087,GO:0019982,Binding to interleukin-7.,interleukin-7 binding,molecular_function
67088,GO:0019983,Binding to interleukin-9.,interleukin-9 binding,molecular_function
67089,GO:0019985,The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.,translesion synthesis,biological_process
67090,GO:0019988,"The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.",charged-tRNA amino acid modification,biological_process
67091,GO:0019990,"The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.",pteridine catabolic process,biological_process
67092,GO:0019991,"The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.",septate junction assembly,biological_process
67093,GO:0019992,"Binding to a diacylglycerol, a diester of glycerol and two fatty acids.",diacylglycerol binding,molecular_function
67094,GO:0020002,The plasma membrane surrounding a host cell.,host cell plasma membrane,cellular_component
67095,GO:0020003,Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.,symbiont-containing vacuole,cellular_component
67096,GO:0020004,The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane.,symbiont-containing vacuolar space,cellular_component
67097,GO:0020005,"The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.",symbiont-containing vacuole membrane,cellular_component
67098,GO:0020006,Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.,symbiont-containing vacuolar membrane network,cellular_component
67099,GO:0020007,"A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.",apical complex,cellular_component
67100,GO:0020008,"A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the ...",rhoptry,cellular_component
67101,GO:0020009,"A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration int...",microneme,cellular_component
67102,GO:0020010,"A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.",conoid,cellular_component
67103,GO:0020011,The plastid organelle found in apicomplexans.,apicoplast,cellular_component
67104,GO:0020013,"Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.",symbiont-mediated perturbation of host erythrocyte aggregation,biological_process
67105,GO:0020014,"Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.",schizogony,biological_process
67106,GO:0020015,A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.,glycosome,cellular_component
67107,GO:0020016,Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.,ciliary pocket,cellular_component
67108,GO:0020018,That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).,ciliary pocket membrane,cellular_component
67109,GO:0020020,Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.,food vacuole,cellular_component
67110,GO:0020022,An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.,acidocalcisome,cellular_component
67111,GO:0020023,A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.,kinetoplast,cellular_component
67112,GO:0020025,Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.,subpellicular microtubule,cellular_component
67113,GO:0020026,Electron-dense organelle with a granular internal matrix found in a apicomplexan parasite; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.,apicomplexan dense granule,cellular_component
67114,GO:0020027,"The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.",hemoglobin metabolic process,biological_process
67115,GO:0020028,The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.,endocytic hemoglobin import into cell,biological_process
67116,GO:0020030,Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.,infected host cell surface knob,cellular_component
67117,GO:0020031,"An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.",polar ring of apical complex,cellular_component
67118,GO:0020032,"An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.",basal ring of apical complex,cellular_component
67119,GO:0020033,A process by which a symbiont evades the host adaptive immune response by changing antigenic determinants on the symbiont surface that are exposed to host antibodies.,antigenic variation,biological_process
67120,GO:0020035,The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.,adhesion of symbiont to microvasculature,biological_process
67121,GO:0020036,"A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.",Maurer's cleft,cellular_component
67122,GO:0020037,"Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.",heme binding,molecular_function
67123,GO:0020038,A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.,subpellicular network,cellular_component
67124,GO:0020039,"The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.",pellicle,cellular_component
67125,GO:0021501,The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.,prechordal plate formation,biological_process
67126,GO:0021502,"The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.",neural fold elevation formation,biological_process
67127,GO:0021503,The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.,neural fold bending,biological_process
67128,GO:0021504,"The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.",neural fold hinge point formation,biological_process
67129,GO:0021505,"The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.",neural fold folding,biological_process
67130,GO:0021506,The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.,anterior neuropore closure,biological_process
67131,GO:0021507,The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.,posterior neuropore closure,biological_process
67132,GO:0021508,The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.,floor plate formation,biological_process
67133,GO:0021509,The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.,roof plate formation,biological_process
67134,GO:0021510,"The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.",spinal cord development,biological_process
67135,GO:0021511,The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.,spinal cord patterning,biological_process
67136,GO:0021512,The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.,spinal cord anterior/posterior patterning,biological_process
67137,GO:0021513,The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.,spinal cord dorsal/ventral patterning,biological_process
67138,GO:0021514,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.,ventral spinal cord interneuron differentiation,biological_process
67139,GO:0021515,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.,cell differentiation in spinal cord,biological_process
67140,GO:0021516,"The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.",dorsal spinal cord development,biological_process
67141,GO:0021517,"The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.",ventral spinal cord development,biological_process
67142,GO:0021518,The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.,spinal cord commissural neuron specification,biological_process
67143,GO:0021519,The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.,spinal cord association neuron specification,biological_process
67144,GO:0021520,The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.,spinal cord motor neuron cell fate specification,biological_process
67145,GO:0021521,The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.,ventral spinal cord interneuron specification,biological_process
67146,GO:0021522,The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.,spinal cord motor neuron differentiation,biological_process
67147,GO:0021523,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.,somatic motor neuron differentiation,biological_process
67148,GO:0021524,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.,visceral motor neuron differentiation,biological_process
67149,GO:0021525,The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.,lateral motor column neuron differentiation,biological_process
67150,GO:0021526,The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.,medial motor column neuron differentiation,biological_process
67151,GO:0021527,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.,spinal cord association neuron differentiation,biological_process
67152,GO:0021528,The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.,commissural neuron differentiation in spinal cord,biological_process
67153,GO:0021529,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.,spinal cord oligodendrocyte cell differentiation,biological_process
67154,GO:0021530,The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.,spinal cord oligodendrocyte cell fate specification,biological_process
67155,GO:0021531,The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.,spinal cord radial glial cell differentiation,biological_process
67156,GO:0021532,The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.,neural tube patterning,biological_process
67157,GO:0021533,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.,cell differentiation in hindbrain,biological_process
67158,GO:0021534,"The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.",cell proliferation in hindbrain,biological_process
67159,GO:0021535,The orderly movement of a cell that will reside in the hindbrain.,cell migration in hindbrain,biological_process
67160,GO:0021536,"The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.",diencephalon development,biological_process
67161,GO:0021537,"The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.",telencephalon development,biological_process
67162,GO:0021538,"The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.",epithalamus development,biological_process
67163,GO:0021539,"The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.",subthalamus development,biological_process
67164,GO:0021540,The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.,corpus callosum morphogenesis,biological_process
67165,GO:0021541,"The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.",ammon gyrus development,biological_process
67166,GO:0021542,"The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.",dentate gyrus development,biological_process
67167,GO:0021543,"The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.",pallium development,biological_process
67168,GO:0021544,"The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.",subpallium development,biological_process
67169,GO:0021545,"The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic gangli...",cranial nerve development,biological_process
67170,GO:0021546,"The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.",rhombomere development,biological_process
67171,GO:0021547,The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.,midbrain-hindbrain boundary initiation,biological_process
67172,GO:0021548,"The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.",pons development,biological_process
67173,GO:0021549,"The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.",cerebellum development,biological_process
67174,GO:0021550,"The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.",medulla oblongata development,biological_process
67175,GO:0021551,"The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",central nervous system morphogenesis,biological_process
67176,GO:0021552,The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.,midbrain-hindbrain boundary structural organization,biological_process
67177,GO:0021553,"The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.",olfactory nerve development,biological_process
67178,GO:0021554,"The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.",optic nerve development,biological_process
67179,GO:0021555,The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.,midbrain-hindbrain boundary morphogenesis,biological_process
67180,GO:0021556,"The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",central nervous system formation,biological_process
67181,GO:0021557,"The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. ...",oculomotor nerve development,biological_process
67182,GO:0021558,"The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.",trochlear nerve development,biological_process
67183,GO:0021559,"The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensor...",trigeminal nerve development,biological_process
67184,GO:0021560,"The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.",abducens nerve development,biological_process
67185,GO:0021561,"The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supp...",facial nerve development,biological_process
67186,GO:0021562,"The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.",vestibulocochlear nerve development,biological_process
67187,GO:0021563,"Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.",glossopharyngeal nerve development,biological_process
67188,GO:0021564,"The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thor...",vagus nerve development,biological_process
67189,GO:0021565,"The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.",accessory nerve development,biological_process
67190,GO:0021566,"The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.",hypoglossal nerve development,biological_process
67191,GO:0021567,"The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 1 development,biological_process
67192,GO:0021568,"The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 2 development,biological_process
67193,GO:0021569,"The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 3 development,biological_process
67194,GO:0021570,"The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 4 development,biological_process
67195,GO:0021571,"The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 5 development,biological_process
67196,GO:0021572,"The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 6 development,biological_process
67197,GO:0021573,"The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 7 development,biological_process
67198,GO:0021574,"The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 8 development,biological_process
67199,GO:0021575,"The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.",hindbrain morphogenesis,biological_process
67200,GO:0021576,"The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.",hindbrain formation,biological_process
67201,GO:0021577,"The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.",hindbrain structural organization,biological_process
67202,GO:0021578,"A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.",hindbrain maturation,biological_process
67203,GO:0021579,"The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.",medulla oblongata morphogenesis,biological_process
67204,GO:0021580,"The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.",medulla oblongata formation,biological_process
67205,GO:0021581,"The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.",medulla oblongata structural organization,biological_process
67206,GO:0021582,"A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.",medulla oblongata maturation,biological_process
67207,GO:0021583,The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.,pons morphogenesis,biological_process
67208,GO:0021584,The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.,pons formation,biological_process
67209,GO:0021585,The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.,pons structural organization,biological_process
67210,GO:0021586,"A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.",pons maturation,biological_process
67211,GO:0021587,"The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.",cerebellum morphogenesis,biological_process
67212,GO:0021588,"The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.",cerebellum formation,biological_process
67213,GO:0021589,"The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.",cerebellum structural organization,biological_process
67214,GO:0021590,"A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.",cerebellum maturation,biological_process
67215,GO:0021591,"The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.",ventricular system development,biological_process
67216,GO:0021592,"The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.",fourth ventricle development,biological_process
67217,GO:0021593,"The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.",rhombomere morphogenesis,biological_process
67218,GO:0021594,"The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.",rhombomere formation,biological_process
67219,GO:0021595,"The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.",rhombomere structural organization,biological_process
67220,GO:0021597,"The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",central nervous system structural organization,biological_process
67221,GO:0021598,The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.,abducens nerve morphogenesis,biological_process
67222,GO:0021599,The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.,abducens nerve formation,biological_process
67223,GO:0021600,The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.,abducens nerve structural organization,biological_process
67224,GO:0021601,"A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.",abducens nerve maturation,biological_process
67225,GO:0021602,"The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.",cranial nerve morphogenesis,biological_process
67226,GO:0021603,"The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ...",cranial nerve formation,biological_process
67227,GO:0021604,"The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the paras...",cranial nerve structural organization,biological_process
67228,GO:0021605,"A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the au...",cranial nerve maturation,biological_process
67229,GO:0021606,"A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.",accessory nerve maturation,biological_process
67230,GO:0021607,The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.,accessory nerve morphogenesis,biological_process
67231,GO:0021608,The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.,accessory nerve formation,biological_process
67232,GO:0021609,The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.,accessory nerve structural organization,biological_process
67233,GO:0021610,"The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous...",facial nerve morphogenesis,biological_process
67234,GO:0021611,"The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which...",facial nerve formation,biological_process
67235,GO:0021612,"The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this gan...",facial nerve structural organization,biological_process
67236,GO:0021613,"A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve bra...",facial nerve maturation,biological_process
67237,GO:0021614,"A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.",glossopharyngeal nerve maturation,biological_process
67238,GO:0021615,"The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.",glossopharyngeal nerve morphogenesis,biological_process
67239,GO:0021616,"The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.",glossopharyngeal nerve formation,biological_process
67240,GO:0021617,"The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic gan...",glossopharyngeal nerve structural organization,biological_process
67241,GO:0021618,The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.,hypoglossal nerve morphogenesis,biological_process
67242,GO:0021619,"A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.",hypoglossal nerve maturation,biological_process
67243,GO:0021620,The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.,hypoglossal nerve formation,biological_process
67244,GO:0021621,The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.,hypoglossal nerve structural organization,biological_process
67245,GO:0021622,"The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens mov...",oculomotor nerve morphogenesis,biological_process
67246,GO:0021623,"The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the ey...",oculomotor nerve formation,biological_process
67247,GO:0021624,"The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also i...",oculomotor nerve structural organization,biological_process
67248,GO:0021625,"A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscle...",oculomotor nerve maturation,biological_process
67249,GO:0021626,"A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.",central nervous system maturation,biological_process
67250,GO:0021627,The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.,olfactory nerve morphogenesis,biological_process
67251,GO:0021628,The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.,olfactory nerve formation,biological_process
67252,GO:0021629,The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.,olfactory nerve structural organization,biological_process
67253,GO:0021630,"A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.",olfactory nerve maturation,biological_process
67254,GO:0021631,"The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.",optic nerve morphogenesis,biological_process
67255,GO:0021632,"A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.",optic nerve maturation,biological_process
67256,GO:0021633,"The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just p...",optic nerve structural organization,biological_process
67257,GO:0021634,"The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.",optic nerve formation,biological_process
67258,GO:0021635,"A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerv...",trigeminal nerve maturation,biological_process
67259,GO:0021636,"The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopa...",trigeminal nerve morphogenesis,biological_process
67260,GO:0021637,"The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of...",trigeminal nerve structural organization,biological_process
67261,GO:0021638,"The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains ...",trigeminal nerve formation,biological_process
67262,GO:0021639,The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.,trochlear nerve morphogenesis,biological_process
67263,GO:0021640,"A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.",trochlear nerve maturation,biological_process
67264,GO:0021641,The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.,trochlear nerve structural organization,biological_process
67265,GO:0021642,The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.,trochlear nerve formation,biological_process
67266,GO:0021643,"A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the phar...",vagus nerve maturation,biological_process
67267,GO:0021644,"The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates ...",vagus nerve morphogenesis,biological_process
67268,GO:0021645,"The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches me...",vagus nerve structural organization,biological_process
67269,GO:0021646,"The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx...",vagus nerve formation,biological_process
67270,GO:0021647,"A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the coc...",vestibulocochlear nerve maturation,biological_process
67271,GO:0021648,"The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.",vestibulocochlear nerve morphogenesis,biological_process
67272,GO:0021649,"The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves i...",vestibulocochlear nerve structural organization,biological_process
67273,GO:0021650,"The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.",vestibulocochlear nerve formation,biological_process
67274,GO:0021651,"The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 1 morphogenesis,biological_process
67275,GO:0021652,"The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 1 formation,biological_process
67276,GO:0021653,"The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 1 structural organization,biological_process
67277,GO:0021654,"The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere boundary formation,biological_process
67278,GO:0021655,"The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 2 morphogenesis,biological_process
67279,GO:0021656,"The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 2 structural organization,biological_process
67280,GO:0021657,"The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 2 formation,biological_process
67281,GO:0021658,"The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 3 morphogenesis,biological_process
67282,GO:0021659,"The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 3 structural organization,biological_process
67283,GO:0021660,"The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 3 formation,biological_process
67284,GO:0021661,"The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 4 morphogenesis,biological_process
67285,GO:0021662,"The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 4 structural organization,biological_process
67286,GO:0021663,"The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 4 formation,biological_process
67287,GO:0021664,"The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 5 morphogenesis,biological_process
67288,GO:0021665,"The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 5 structural organization,biological_process
67289,GO:0021666,"The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 5 formation,biological_process
67290,GO:0021667,"The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 6 morphogenesis,biological_process
67291,GO:0021668,"The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 6 structural organization,biological_process
67292,GO:0021669,"The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 6 formation,biological_process
67293,GO:0021670,"The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of th...",lateral ventricle development,biological_process
67294,GO:0021671,"The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 7 morphogenesis,biological_process
67295,GO:0021672,"The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 7 structural organization,biological_process
67296,GO:0021673,"The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 7 formation,biological_process
67297,GO:0021674,"The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 8 morphogenesis,biological_process
67298,GO:0021675,"The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.",nerve development,biological_process
67299,GO:0021676,"The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.",rhombomere 8 structural organization,biological_process
67300,GO:0021677,"The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.",rhombomere 8 formation,biological_process
67301,GO:0021678,"The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular ...",third ventricle development,biological_process
67302,GO:0021679,"The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.",cerebellar molecular layer development,biological_process
67303,GO:0021680,"The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar ...",cerebellar Purkinje cell layer development,biological_process
67304,GO:0021681,"The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white ma...",cerebellar granular layer development,biological_process
67305,GO:0021682,"A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.",nerve maturation,biological_process
67306,GO:0021683,"The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axo...",cerebellar granular layer morphogenesis,biological_process
67307,GO:0021684,"The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the wh...",cerebellar granular layer formation,biological_process
67308,GO:0021685,"The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy ...",cerebellar granular layer structural organization,biological_process
67309,GO:0021686,"A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nucl...",cerebellar granular layer maturation,biological_process
67310,GO:0021687,"The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.",cerebellar molecular layer morphogenesis,biological_process
67311,GO:0021688,"The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.",cerebellar molecular layer formation,biological_process
67312,GO:0021689,"The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.",cerebellar molecular layer structural organization,biological_process
67313,GO:0021690,"A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.",cerebellar molecular layer maturation,biological_process
67314,GO:0021691,"A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output o...",cerebellar Purkinje cell layer maturation,biological_process
67315,GO:0021692,The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project i...,cerebellar Purkinje cell layer morphogenesis,biological_process
67316,GO:0021693,The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibi...,cerebellar Purkinje cell layer structural organization,biological_process
67317,GO:0021694,The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cereb...,cerebellar Purkinje cell layer formation,biological_process
67318,GO:0021695,"The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for th...",cerebellar cortex development,biological_process
67319,GO:0021696,"The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, per...",cerebellar cortex morphogenesis,biological_process
67320,GO:0021697,"The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible ...",cerebellar cortex formation,biological_process
67321,GO:0021698,The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. ...,cerebellar cortex structural organization,biological_process
67322,GO:0021699,"A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are r...",cerebellar cortex maturation,biological_process
67323,GO:0021700,"A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.",developmental maturation,biological_process
67324,GO:0021701,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,cerebellar Golgi cell differentiation,biological_process
67325,GO:0021702,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.,cerebellar Purkinje cell differentiation,biological_process
67326,GO:0021703,"The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.",locus ceruleus development,biological_process
67327,GO:0021704,"The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.",locus ceruleus morphogenesis,biological_process
67328,GO:0021705,"The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.",locus ceruleus formation,biological_process
67329,GO:0021706,"A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.",locus ceruleus maturation,biological_process
67330,GO:0021707,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.,cerebellar granule cell differentiation,biological_process
67331,GO:0021708,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,Lugaro cell differentiation,biological_process
67332,GO:0021709,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,cerebellar basket cell differentiation,biological_process
67333,GO:0021710,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,cerebellar stellate cell differentiation,biological_process
67334,GO:0021711,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.,cerebellar unipolar brush cell differentiation,biological_process
67335,GO:0021712,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,candelabrum cell differentiation,biological_process
67336,GO:0021713,"The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.",inferior olivary nucleus development,biological_process
67337,GO:0021714,"The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.",inferior olivary nucleus morphogenesis,biological_process
67338,GO:0021715,"The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.",inferior olivary nucleus formation,biological_process
67339,GO:0021716,"The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.",inferior olivary nucleus structural organization,biological_process
67340,GO:0021717,"A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movem...",inferior olivary nucleus maturation,biological_process
67341,GO:0021718,"The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.",superior olivary nucleus development,biological_process
67342,GO:0021719,"The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.",superior olivary nucleus morphogenesis,biological_process
67343,GO:0021720,"The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.",superior olivary nucleus formation,biological_process
67344,GO:0021721,"The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.",superior olivary nucleus structural organization,biological_process
67345,GO:0021722,"A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.",superior olivary nucleus maturation,biological_process
67346,GO:0021723,"The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.",medullary reticular formation development,biological_process
67347,GO:0021724,"The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.",inferior raphe nucleus development,biological_process
67348,GO:0021725,"The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.",superior raphe nucleus development,biological_process
67349,GO:0021726,"The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.",lateral reticular nucleus development,biological_process
67350,GO:0021727,"The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.",intermediate reticular formation development,biological_process
67351,GO:0021728,"The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.",inferior reticular formation development,biological_process
67352,GO:0021729,"The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.",superior reticular formation development,biological_process
67353,GO:0021730,"The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.",trigeminal sensory nucleus development,biological_process
67354,GO:0021731,"The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.",trigeminal motor nucleus development,biological_process
67355,GO:0021732,"A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.",midbrain-hindbrain boundary maturation,biological_process
67356,GO:0021735,"The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.",dentate nucleus development,biological_process
67357,GO:0021736,"The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.",globose nucleus development,biological_process
67358,GO:0021737,"The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.",emboliform nucleus development,biological_process
67359,GO:0021738,"The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.",fastigial nucleus development,biological_process
67360,GO:0021739,"The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.",mesencephalic trigeminal nucleus development,biological_process
67361,GO:0021740,"The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.",principal sensory nucleus of trigeminal nerve development,biological_process
67362,GO:0021741,"The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.",spinal trigeminal nucleus development,biological_process
67363,GO:0021742,"The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.",abducens nucleus development,biological_process
67364,GO:0021743,"The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.",hypoglossal nucleus development,biological_process
67365,GO:0021744,"The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.",dorsal motor nucleus of vagus nerve development,biological_process
67366,GO:0021745,"The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.",nucleus ambiguus development,biological_process
67367,GO:0021746,"The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.",solitary nucleus development,biological_process
67368,GO:0021747,"The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.",cochlear nucleus development,biological_process
67369,GO:0021748,"The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.",dorsal cochlear nucleus development,biological_process
67370,GO:0021749,"The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.",ventral cochlear nucleus development,biological_process
67371,GO:0021750,"The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.",vestibular nucleus development,biological_process
67372,GO:0021751,"The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.",salivary nucleus development,biological_process
67373,GO:0021752,"The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.",inferior salivary nucleus development,biological_process
67374,GO:0021753,"The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.",superior salivary nucleus development,biological_process
67375,GO:0021754,"The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.",facial nucleus development,biological_process
67376,GO:0021755,The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.,eurydendroid cell differentiation,biological_process
67377,GO:0021756,"The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.",striatum development,biological_process
67378,GO:0021757,The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.,caudate nucleus development,biological_process
67379,GO:0021758,The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.,putamen development,biological_process
67380,GO:0021759,The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.,globus pallidus development,biological_process
67381,GO:0021761,"The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.",limbic system development,biological_process
67382,GO:0021762,The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).,substantia nigra development,biological_process
67383,GO:0021763,The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.,subthalamic nucleus development,biological_process
67384,GO:0021764,The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.,amygdala development,biological_process
67385,GO:0021765,The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.,cingulate gyrus development,biological_process
67386,GO:0021766,The progression of the hippocampus over time from its initial formation until its mature state.,hippocampus development,biological_process
67387,GO:0021767,The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.,mammillary body development,biological_process
67388,GO:0021768,"The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.",nucleus accumbens development,biological_process
67389,GO:0021769,The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.,orbitofrontal cortex development,biological_process
67390,GO:0021770,The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.,parahippocampal gyrus development,biological_process
67391,GO:0021771,The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.,lateral geniculate nucleus development,biological_process
67392,GO:0021772,The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.,olfactory bulb development,biological_process
67393,GO:0021773,The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.,striatal medium spiny neuron differentiation,biological_process
67394,GO:0021775,The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.,smoothened signaling pathway involved in ventral spinal cord interneuron specification,biological_process
67395,GO:0021776,The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.,smoothened signaling pathway involved in spinal cord motor neuron cell fate specification,biological_process
67396,GO:0021778,"The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",oligodendrocyte cell fate specification,biological_process
67397,GO:0021779,The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.,oligodendrocyte cell fate commitment,biological_process
67398,GO:0021780,"The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",glial cell fate specification,biological_process
67399,GO:0021781,The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.,glial cell fate commitment,biological_process
67400,GO:0021782,"The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",glial cell development,biological_process
67401,GO:0021783,"The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.",preganglionic parasympathetic fiber development,biological_process
67402,GO:0021784,"The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarin...",postganglionic parasympathetic fiber development,biological_process
67403,GO:0021785,"The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",branchiomotor neuron axon guidance,biological_process
67404,GO:0021786,"The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",branchiomotor neuron axon guidance in neural tube,biological_process
67405,GO:0021787,"The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemorepulsion of branchiomotor neuron axon in neural tube,biological_process
67406,GO:0021788,"The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemoattraction of branchiomotor neuron axon in neural tube,biological_process
67407,GO:0021789,"The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",branchiomotor neuron axon guidance in branchial arch mesenchyme,biological_process
67408,GO:0021790,"The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme,biological_process
67409,GO:0021791,"The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme,biological_process
67410,GO:0021792,"The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemoattraction of branchiomotor axon,biological_process
67411,GO:0021793,"The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.",chemorepulsion of branchiomotor axon,biological_process
67412,GO:0021794,"The process in which the thalamus changes over time, from its initial formation to its mature state.",thalamus development,biological_process
67413,GO:0021795,The orderly movement of cells from one site to another in the cerebral cortex.,cerebral cortex cell migration,biological_process
67414,GO:0021796,The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.,cerebral cortex regionalization,biological_process
67415,GO:0021797,The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.,forebrain anterior/posterior pattern specification,biological_process
67416,GO:0021798,The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.,forebrain dorsal/ventral pattern formation,biological_process
67417,GO:0021799,The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.,cerebral cortex radially oriented cell migration,biological_process
67418,GO:0021800,The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.,cerebral cortex tangential migration,biological_process
67419,GO:0021801,The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.,cerebral cortex radial glia-guided migration,biological_process
67420,GO:0021802,The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.,somal translocation,biological_process
67421,GO:0021803,The extension of a long process to the pial surface as a cell leaves the ventricular zone.,extension of leading cell process to pial surface,biological_process
67422,GO:0021804,The process that results in the loss of attachments of a cell in the ventricular zone.,negative regulation of cell adhesion in ventricular zone,biological_process
67423,GO:0021807,The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.,motogenic signaling initiating cell movement in cerebral cortex,biological_process
67424,GO:0021812,The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.,neuronal-glial interaction involved in cerebral cortex radial glia guided migration,biological_process
67425,GO:0021813,The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.,cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration,biological_process
67426,GO:0021814,The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.,cell motility involved in cerebral cortex radial glia guided migration,biological_process
67427,GO:0021815,Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.,modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration,biological_process
67428,GO:0021816,"The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.",extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration,biological_process
67429,GO:0021817,The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.,nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration,biological_process
67430,GO:0021819,The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.,layer formation in cerebral cortex,biological_process
67431,GO:0021822,The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.,negative regulation of cell motility involved in cerebral cortex radial glia guided migration,biological_process
67432,GO:0021823,The process in which neurons interact with each other to promote migration along a tangential plane.,cerebral cortex tangential migration using cell-cell interactions,biological_process
67433,GO:0021824,The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.,cerebral cortex tangential migration using cell-axon interactions,biological_process
67434,GO:0021825,"The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.",substrate-dependent cerebral cortex tangential migration,biological_process
67435,GO:0021826,"The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.",substrate-independent telencephalic tangential migration,biological_process
67436,GO:0021827,The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.,postnatal olfactory bulb interneuron migration,biological_process
67437,GO:0021828,The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.,gonadotrophin-releasing hormone neuronal migration to the hypothalamus,biological_process
67438,GO:0021829,The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.,oligodendrocyte cell migration from the subpallium to the cortex,biological_process
67439,GO:0021830,The directed movement of interneurons from the subpallium to the cortex during forebrain development.,interneuron migration from the subpallium to the cortex,biological_process
67440,GO:0021831,The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.,embryonic olfactory bulb interneuron precursor migration,biological_process
67441,GO:0021834,The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.,chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration,biological_process
67442,GO:0021836,The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.,chemorepulsion involved in postnatal olfactory bulb interneuron migration,biological_process
67443,GO:0021840,The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.,directional guidance of interneurons involved in migration from the subpallium to the cortex,biological_process
67444,GO:0021842,The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.,chemorepulsion involved in interneuron migration from the subpallium to the cortex,biological_process
67445,GO:0021843,The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.,substrate-independent telencephalic tangential interneuron migration,biological_process
67446,GO:0021846,The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.,cell proliferation in forebrain,biological_process
67447,GO:0021847,The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.,ventricular zone neuroblast division,biological_process
67448,GO:0021848,The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.,neuroblast division in subpallium,biological_process
67449,GO:0021849,The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.,neuroblast division in subventricular zone,biological_process
67450,GO:0021850,The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.,subpallium glioblast cell division,biological_process
67451,GO:0021851,The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.,neuroblast division in dorsal lateral ganglionic eminence,biological_process
67452,GO:0021852,The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.,pyramidal neuron migration to cerebral cortex,biological_process
67453,GO:0021853,The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.,cerebral cortex GABAergic interneuron migration,biological_process
67454,GO:0021854,"The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.",hypothalamus development,biological_process
67455,GO:0021855,The directed movement of a cell into the hypothalamus region of the forebrain.,hypothalamus cell migration,biological_process
67456,GO:0021856,The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.,hypothalamic tangential migration using cell-axon interactions,biological_process
67457,GO:0021858,The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.,GABAergic neuron differentiation in basal ganglia,biological_process
67458,GO:0021859,"The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.",pyramidal neuron differentiation,biological_process
67459,GO:0021860,The progression of a pyramidal neuron from its initial formation to its mature state.,pyramidal neuron development,biological_process
67460,GO:0021861,"The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.",forebrain radial glial cell differentiation,biological_process
67461,GO:0021862,The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.,early neuron differentiation in forebrain,biological_process
67462,GO:0021863,"The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.",forebrain neuroblast differentiation,biological_process
67463,GO:0021869,The mitotic division of a basal progenitor giving rise to two neurons.,forebrain ventricular zone progenitor cell division,biological_process
67464,GO:0021870,"The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.",Cajal-Retzius cell differentiation,biological_process
67465,GO:0021871,The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.,forebrain regionalization,biological_process
67466,GO:0021872,The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.,forebrain generation of neurons,biological_process
67467,GO:0021873,The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.,forebrain neuroblast division,biological_process
67468,GO:0021874,The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.,Wnt signaling pathway involved in forebrain neuroblast division,biological_process
67469,GO:0021877,The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.,forebrain neuron fate commitment,biological_process
67470,GO:0021878,The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.,forebrain astrocyte fate commitment,biological_process
67471,GO:0021879,The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.,forebrain neuron differentiation,biological_process
67472,GO:0021884,"The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.",forebrain neuron development,biological_process
67473,GO:0021885,The orderly movement of a cell from one site to another at least one of which is located in the forebrain.,forebrain cell migration,biological_process
67474,GO:0021886,The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.,hypothalamus gonadotrophin-releasing hormone neuron differentiation,biological_process
67475,GO:0021887,The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.,hypothalamus gonadotrophin-releasing hormone neuron fate commitment,biological_process
67476,GO:0021888,"The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.",hypothalamus gonadotrophin-releasing hormone neuron development,biological_process
67477,GO:0021889,The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.,olfactory bulb interneuron differentiation,biological_process
67478,GO:0021890,The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.,olfactory bulb interneuron fate commitment,biological_process
67479,GO:0021891,"The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.",olfactory bulb interneuron development,biological_process
67480,GO:0021892,The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.,cerebral cortex GABAergic interneuron differentiation,biological_process
67481,GO:0021893,The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.,cerebral cortex GABAergic interneuron fate commitment,biological_process
67482,GO:0021894,"The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.",cerebral cortex GABAergic interneuron development,biological_process
67483,GO:0021895,The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.,cerebral cortex neuron differentiation,biological_process
67484,GO:0021896,The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.,forebrain astrocyte differentiation,biological_process
67485,GO:0021897,"The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.",forebrain astrocyte development,biological_process
67486,GO:0021898,The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.,commitment of multipotent stem cells to neuronal lineage in forebrain,biological_process
67487,GO:0021899,The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.,fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment,biological_process
67488,GO:0021900,The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.,ventricular zone cell fate commitment,biological_process
67489,GO:0021901,The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.,early neuron fate commitment in forebrain,biological_process
67490,GO:0021902,The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.,commitment of neuronal cell to specific neuron type in forebrain,biological_process
67491,GO:0021903,The process in which the neural tube is divided into specific regions along the rostrocaudal axis.,rostrocaudal neural tube patterning,biological_process
67492,GO:0021904,The process in which the neural tube is regionalized in the dorsoventral axis.,dorsal/ventral neural tube patterning,biological_process
67493,GO:0021905,The process whose specific outcome is the creation of the forebrain-midbrain boundary.,forebrain-midbrain boundary formation,biological_process
67494,GO:0021906,The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.,hindbrain-spinal cord boundary formation,biological_process
67495,GO:0021910,The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.,smoothened signaling pathway involved in ventral spinal cord patterning,biological_process
67496,GO:0021915,"The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.",neural tube development,biological_process
67497,GO:0021916,Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.,inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors,biological_process
67498,GO:0021917,The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.,somatic motor neuron fate commitment,biological_process
67499,GO:0021921,"The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.",regulation of cell proliferation in dorsal spinal cord,biological_process
67500,GO:0021923,"The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.",cell proliferation in hindbrain ventricular zone,biological_process
67501,GO:0021924,The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.,cell proliferation in external granule layer,biological_process
67502,GO:0021925,The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.,cerebellar Purkinje cell precursor proliferation,biological_process
67503,GO:0021926,The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,Golgi cell precursor proliferation,biological_process
67504,GO:0021927,The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.,deep nuclear neuron precursor proliferation,biological_process
67505,GO:0021928,The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,basket cell precursor proliferation,biological_process
67506,GO:0021929,The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.,stellate cell precursor proliferation,biological_process
67507,GO:0021930,The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.,cerebellar granule cell precursor proliferation,biological_process
67508,GO:0021931,The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.,rostral hindbrain neuronal precursor cell proliferation,biological_process
67509,GO:0021932,The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.,hindbrain radial glia guided cell migration,biological_process
67510,GO:0021933,The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.,radial glia guided migration of cerebellar granule cell,biological_process
67511,GO:0021934,The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.,hindbrain tangential cell migration,biological_process
67512,GO:0021935,The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.,cerebellar granule cell precursor tangential migration,biological_process
67513,GO:0021936,"The process that modulates the frequency, rate or extent of granule cell precursor proliferation.",regulation of cerebellar granule cell precursor proliferation,biological_process
67514,GO:0021937,Any process that mediates the transfer of information from Purkinje cells to granule cell precursors.,cerebellar Purkinje cell-granule cell precursor cell signaling,biological_process
67515,GO:0021940,The process that activates or increases the rate or extent of granule cell precursor proliferation.,positive regulation of cerebellar granule cell precursor proliferation,biological_process
67516,GO:0021941,"The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.",negative regulation of cerebellar granule cell precursor proliferation,biological_process
67517,GO:0021942,The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.,radial glia guided migration of Purkinje cell,biological_process
67518,GO:0021943,The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.,formation of radial glial scaffolds,biological_process
67519,GO:0021944,The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.,neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration,biological_process
67520,GO:0021946,The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.,deep nuclear neuron cell migration,biological_process
67521,GO:0021947,The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.,outward migration of deep nuclear neurons,biological_process
67522,GO:0021948,The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.,inward migration of deep nuclear neurons,biological_process
67523,GO:0021949,"The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.",brainstem precerebellar neuron precursor migration,biological_process
67524,GO:0021952,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.",central nervous system projection neuron axonogenesis,biological_process
67525,GO:0021953,The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.,central nervous system neuron differentiation,biological_process
67526,GO:0021954,"The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.",central nervous system neuron development,biological_process
67527,GO:0021955,Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.,central nervous system neuron axonogenesis,biological_process
67528,GO:0021956,Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.,central nervous system interneuron axonogenesis,biological_process
67529,GO:0021957,"Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.",corticospinal tract morphogenesis,biological_process
67530,GO:0021958,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.",gracilis tract morphogenesis,biological_process
67531,GO:0021959,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.",cuneatus tract morphogenesis,biological_process
67532,GO:0021960,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.",anterior commissure morphogenesis,biological_process
67533,GO:0021961,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.",posterior commissure morphogenesis,biological_process
67534,GO:0021962,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.",vestibulospinal tract morphogenesis,biological_process
67535,GO:0021963,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.",spinothalamic tract morphogenesis,biological_process
67536,GO:0021964,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.",rubrospinal tract morphogenesis,biological_process
67537,GO:0021965,The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.,spinal cord ventral commissure morphogenesis,biological_process
67538,GO:0021966,The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance,biological_process
67539,GO:0021967,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through the cerebral cortex,biological_process
67540,GO:0021968,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through the internal capsule,biological_process
67541,GO:0021969,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through the cerebral peduncle,biological_process
67542,GO:0021970,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through the basilar pons,biological_process
67543,GO:0021971,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through the medullary pyramid,biological_process
67544,GO:0021972,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.,corticospinal neuron axon guidance through spinal cord,biological_process
67545,GO:0021973,The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.,corticospinal neuron axon decussation,biological_process
67546,GO:0021974,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.",trigeminothalamic tract morphogenesis,biological_process
67547,GO:0021975,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.",pons reticulospinal tract morphogenesis,biological_process
67548,GO:0021976,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.",medulla reticulospinal tract morphogenesis,biological_process
67549,GO:0021977,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.",tectospinal tract morphogenesis,biological_process
67550,GO:0021978,The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.,telencephalon regionalization,biological_process
67551,GO:0021979,The differentiation of cells that will contribute to the structure and function of the hypothalamus.,hypothalamus cell differentiation,biological_process
67552,GO:0021980,The orderly movement of cells from one site to another in the subpallium.,subpallium cell migration,biological_process
67553,GO:0021981,The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.,subpallium radially oriented migration,biological_process
67554,GO:0021982,The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.,pineal gland development,biological_process
67555,GO:0021983,The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.,pituitary gland development,biological_process
67556,GO:0021984,The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.,adenohypophysis development,biological_process
67557,GO:0021985,The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.,neurohypophysis development,biological_process
67558,GO:0021986,The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.,habenula development,biological_process
67559,GO:0021987,The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.,cerebral cortex development,biological_process
67560,GO:0021988,The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.,olfactory lobe development,biological_process
67561,GO:0021989,The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.,olfactory cortex development,biological_process
67562,GO:0021990,"The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.",neural plate formation,biological_process
67563,GO:0021991,The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.,neural plate thickening,biological_process
67564,GO:0021993,The process in which closure points are established at multiple points and along the neural rostrocaudal axis.,initiation of neural tube closure,biological_process
67565,GO:0021994,The process in which the neural folds are fused extending from the initial closure points.,progression of neural tube closure,biological_process
67566,GO:0021995,The process of joining together the neural folds at either end of the neural tube.,neuropore closure,biological_process
67567,GO:0021996,The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.,lamina terminalis formation,biological_process
67568,GO:0021997,The pattern specification process in which the axes of the nervous system are established.,neural plate axis specification,biological_process
67569,GO:0021998,The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.,neural plate mediolateral regionalization,biological_process
67570,GO:0021999,The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.,neural plate anterior/posterior regionalization,biological_process
67571,GO:0022000,The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.,forebrain induction by the anterior neural ridge,biological_process
67572,GO:0022001,"Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.",negative regulation of anterior neural cell fate commitment of the neural plate,biological_process
67573,GO:0022003,"The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.",negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway,biological_process
67574,GO:0022004,A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.,midbrain-hindbrain boundary maturation during brain development,biological_process
67575,GO:0022005,A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.,midbrain-hindbrain boundary maturation during neural plate development,biological_process
67576,GO:0022006,The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.,zona limitans intrathalamica formation,biological_process
67577,GO:0022007,"The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.",convergent extension involved in neural plate elongation,biological_process
67578,GO:0022008,Generation of cells within the nervous system.,neurogenesis,biological_process
67579,GO:0022009,"The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.",central nervous system vasculogenesis,biological_process
67580,GO:0022010,The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.,central nervous system myelination,biological_process
67581,GO:0022011,The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.,myelination in peripheral nervous system,biological_process
67582,GO:0022012,"The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.",subpallium cell proliferation in forebrain,biological_process
67583,GO:0022013,"The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.",pallium cell proliferation in forebrain,biological_process
67584,GO:0022015,The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.,radial glial cell division in pallium,biological_process
67585,GO:0022016,The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.,pallium glioblast division,biological_process
67586,GO:0022017,The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.,neuroblast division in pallium,biological_process
67587,GO:0022018,"The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.",lateral ganglionic eminence cell proliferation,biological_process
67588,GO:0022019,"The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.",dorsal lateral ganglionic eminence cell proliferation,biological_process
67589,GO:0022020,"The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.",medial ganglionic eminence cell proliferation,biological_process
67590,GO:0022021,"The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.",caudal ganglionic eminence cell proliferation,biological_process
67591,GO:0022022,"The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.",septal cell proliferation,biological_process
67592,GO:0022023,The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.,radial glial cell fate commitment in forebrain,biological_process
67593,GO:0022027,"The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.",interkinetic nuclear migration,biological_process
67594,GO:0022028,The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.,tangential migration from the subventricular zone to the olfactory bulb,biological_process
67595,GO:0022029,The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.,telencephalon cell migration,biological_process
67596,GO:0022030,The orderly movement of glial cells through the telencephalon.,telencephalon glial cell migration,biological_process
67597,GO:0022031,The orderly movement of an astrocyte cell through the telencephalon.,telencephalon astrocyte cell migration,biological_process
67598,GO:0022032,"The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.",telencephalon oligodendrocyte cell migration,biological_process
67599,GO:0022033,The orderly movement of microglial cells through the telencephalon.,telencephalon microglial cell migration,biological_process
67600,GO:0022034,"The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.",rhombomere cell proliferation,biological_process
67601,GO:0022035,The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.,rhombomere cell migration,biological_process
67602,GO:0022036,The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.,rhombomere cell differentiation,biological_process
67603,GO:0022037,"The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.",metencephalon development,biological_process
67604,GO:0022038,"The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.",corpus callosum development,biological_process
67605,GO:0022400,"Any process that modulates the frequency, rate or extent of opsin-mediated signaling.",regulation of opsin-mediated signaling pathway,biological_process
67606,GO:0022401,The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.,negative adaptation of signaling pathway,biological_process
67607,GO:0022402,The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.,cell cycle process,biological_process
67608,GO:0022403,One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.,cell cycle phase,biological_process
67609,GO:0022404,"A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.",molting cycle process,biological_process
67610,GO:0022405,"A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.",hair cycle process,biological_process
67611,GO:0022406,The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.,membrane docking,biological_process
67612,GO:0022407,"Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.",regulation of cell-cell adhesion,biological_process
67613,GO:0022408,"Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.",negative regulation of cell-cell adhesion,biological_process
67614,GO:0022409,Any process that activates or increases the rate or extent of cell adhesion to another cell.,positive regulation of cell-cell adhesion,biological_process
67615,GO:0022410,A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.,circadian sleep/wake cycle process,biological_process
67616,GO:0022411,A cellular process that results in the breakdown of a cellular component.,cellular component disassembly,biological_process
67617,GO:0022412,"A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.",cellular process involved in reproduction in multicellular organism,biological_process
67618,GO:0022413,"A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.",reproductive process in single-celled organism,biological_process
67619,GO:0022414,A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.,reproductive process,biological_process
67620,GO:0022416,"The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.",chaeta development,biological_process
67621,GO:0022600,"A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",digestive system process,biological_process
67622,GO:0022601,"The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.",menstrual cycle phase,biological_process
67623,GO:0022602,"A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.",ovulation cycle process,biological_process
67624,GO:0022603,"Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.",regulation of anatomical structure morphogenesis,biological_process
67625,GO:0022604,"Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.",regulation of cell morphogenesis,biological_process
67626,GO:0022605,A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.,mammalian oogenesis stage,biological_process
67627,GO:0022606,The specification and formation of the polarity of a cell along its proximal/distal axis.,establishment of proximal/distal cell polarity,biological_process
67628,GO:0022607,"The aggregation, arrangement and bonding together of a cellular component.",cellular component assembly,biological_process
67629,GO:0022608,The attachment of a multicellular organism to a substrate or other organism.,multicellular organism adhesion,biological_process
67630,GO:0022609,The attachment of a multicellular organism to a surface or material.,multicellular organism adhesion to substrate,biological_process
67631,GO:0022611,"A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.",dormancy process,biological_process
67632,GO:0022612,The process in which the anatomical structures of a gland are generated and organized.,gland morphogenesis,biological_process
67633,GO:0022613,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.",ribonucleoprotein complex biogenesis,biological_process
67634,GO:0022614,"The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.",membrane to membrane docking,biological_process
67635,GO:0022615,"The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.",protein to membrane docking,biological_process
67636,GO:0022616,The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.,DNA strand elongation,biological_process
67637,GO:0022617,A process that results in the breakdown of the extracellular matrix.,extracellular matrix disassembly,biological_process
67638,GO:0022618,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.",protein-RNA complex assembly,biological_process
67639,GO:0022619,The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.,generative cell differentiation,biological_process
67640,GO:0022620,The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube.,microgametophyte vegetative cell differentiation,biological_process
67641,GO:0022622,"The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.",root system development,biological_process
67642,GO:0022623,"A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.",proteasome-activating nucleotidase complex,cellular_component
67643,GO:0022624,"A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.",proteasome accessory complex,cellular_component
67644,GO:0022625,The large subunit of a ribosome located in the cytosol.,cytosolic large ribosomal subunit,cellular_component
67645,GO:0022626,A ribosome located in the cytosol.,cytosolic ribosome,cellular_component
67646,GO:0022627,The small subunit of a ribosome located in the cytosol.,cytosolic small ribosomal subunit,cellular_component
67647,GO:0022628,The large subunit of a ribosome contained within a chloroplast.,chloroplast large ribosomal subunit,cellular_component
67648,GO:0022629,The small subunit of a ribosome contained within a chloroplast.,chloroplast small ribosomal subunit,cellular_component
67649,GO:0022803,"Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.",passive transmembrane transporter activity,molecular_function
67650,GO:0022804,"Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.",active transmembrane transporter activity,molecular_function
67651,GO:0022809,Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.,mobile ion carrier activity,molecular_function
67652,GO:0022810,"Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",membrane potential driven uniporter activity,molecular_function
67653,GO:0022818,"Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",sodium ion uniporter activity,molecular_function
67654,GO:0022819,"Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",potassium ion uniporter activity,molecular_function
67655,GO:0022821,Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.,solute:potassium antiporter activity,molecular_function
67656,GO:0022824,Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.,transmitter-gated monoatomic ion channel activity,molecular_function
67657,GO:0022829,"Enables the energy-independent facilitated diffusion of propanediol through a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.",wide pore channel activity,molecular_function
67658,GO:0022831,Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.,"narrow pore, gated channel activity",molecular_function
67659,GO:0022832,Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated channel activity,molecular_function
67660,GO:0022834,Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated channel activity,molecular_function
67661,GO:0022835,Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.,transmitter-gated channel activity,molecular_function
67662,GO:0022836,Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.,gated channel activity,molecular_function
67663,GO:0022839,Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.,monoatomic ion-gated channel activity,molecular_function
67664,GO:0022840,Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.,leak channel activity,molecular_function
67665,GO:0022841,Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.,potassium ion leak channel activity,molecular_function
67666,GO:0022842,Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.,narrow pore channel activity,molecular_function
67667,GO:0022843,Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated monoatomic cation channel activity,molecular_function
67668,GO:0022848,Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.,acetylcholine-gated monoatomic cation-selective channel activity,molecular_function
67669,GO:0022849,Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.,glutamate-gated calcium ion channel activity,molecular_function
67670,GO:0022850,Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.,serotonin-gated monoatomic cation channel activity,molecular_function
67671,GO:0022851,Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.,GABA-gated chloride ion channel activity,molecular_function
67672,GO:0022852,Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.,glycine-gated chloride ion channel activity,molecular_function
67673,GO:0022853,Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.,active monoatomic ion transmembrane transporter activity,molecular_function
67674,GO:0022855,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity,molecular_function
67675,GO:0022856,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity,molecular_function
67676,GO:0022857,"Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.",transmembrane transporter activity,molecular_function
67677,GO:0022858,Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.,alanine transmembrane transporter activity,molecular_function
67678,GO:0022869,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity,molecular_function
67679,GO:0022870,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane according to the reaction: D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity,molecular_function
67680,GO:0022871,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity,molecular_function
67681,GO:0022872,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity,molecular_function
67682,GO:0022873,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity,molecular_function
67683,GO:0022874,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane according to the reaction: D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho-beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]. This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity,molecular_function
67684,GO:0022875,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity,molecular_function
67685,GO:0022876,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity,molecular_function
67686,GO:0022877,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity,molecular_function
67687,GO:0022878,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity,molecular_function
67688,GO:0022879,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity,molecular_function
67689,GO:0022880,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane by the reaction: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity,molecular_function
67690,GO:0022881,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity,molecular_function
67691,GO:0022882,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity,molecular_function
67692,GO:0022883,Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.,zinc efflux transmembrane transporter activity,molecular_function
67693,GO:0022884,Enables the transfer of a macromolecule from one side of a membrane to the other.,macromolecule transmembrane transporter activity,molecular_function
67694,GO:0022885,Enables the transfer of a bacteriocin from one side of a membrane to the other.,bacteriocin transmembrane transporter activity,molecular_function
67695,GO:0022886,Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.,channel-forming ionophore activity,molecular_function
67696,GO:0022893,Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity tryptophan transmembrane transporter activity,molecular_function
67697,GO:0022894,Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore o...,intermediate conductance calcium-activated potassium channel activity,molecular_function
67698,GO:0022898,"Any process that modulates the frequency, rate or extent of transmembrane transporter activity.",regulation of transmembrane transporter activity,biological_process
67699,GO:0022900,A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.,electron transport chain,biological_process
67700,GO:0022904,A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.,respiratory electron transport chain,biological_process
67701,GO:0023002,Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.,nuclear migration to embryo sac poles,biological_process
67702,GO:0023003,"Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.",nuclear migration to the embryo sac center,biological_process
67703,GO:0023019,"Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.",signal transduction involved in regulation of gene expression,biological_process
67704,GO:0023021,The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.,termination of signal transduction,biological_process
67705,GO:0023022,The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.,termination of T cell signal transduction,biological_process
67706,GO:0023023,Binding to a major histocompatibility complex.,MHC protein complex binding,molecular_function
67707,GO:0023024,Binding to a class I major histocompatibility complex.,MHC class I protein complex binding,molecular_function
67708,GO:0023025,Binding to a class Ib major histocompatibility complex.,MHC class Ib protein complex binding,molecular_function
67709,GO:0023026,Binding to a class II major histocompatibility complex.,MHC class II protein complex binding,molecular_function
67710,GO:0023027,Binding to a major histocompatibility complex class I molecules via the antigen binding groove.,"MHC class I protein binding, via antigen binding groove",molecular_function
67711,GO:0023028,Binding to a major histocompatibility complex class I molecules via the lateral surface.,"MHC class I protein binding, via lateral surface",molecular_function
67712,GO:0023029,Binding to a major histocompatibility complex class Ib molecules.,MHC class Ib protein binding,molecular_function
67713,GO:0023030,Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.,"MHC class Ib protein binding, via antigen binding groove",molecular_function
67714,GO:0023031,Binding to a major histocompatibility complex class Ib molecules via the lateral surface.,"MHC class Ib protein binding, via lateral surface",molecular_function
67715,GO:0023035,"The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.",CD40 signaling pathway,biological_process
67716,GO:0023041,"The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.",neuronal signal transduction,biological_process
67717,GO:0023051,"Any process that modulates the frequency, rate or extent of a signaling process.",regulation of signaling,biological_process
67718,GO:0023052,The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.,signaling,biological_process
67719,GO:0023056,"Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.",positive regulation of signaling,biological_process
67720,GO:0023057,"Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.",negative regulation of signaling,biological_process
67721,GO:0023058,The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.,adaptation of signaling pathway,biological_process
67722,GO:0023059,The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.,positive adaptation of signaling pathway,biological_process
67723,GO:0023061,The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.,signal release,biological_process
67724,GO:0030001,"The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",metal ion transport,biological_process
67725,GO:0030002,A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom.,intracellular monoatomic anion homeostasis,biological_process
67726,GO:0030003,A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.,intracellular monoatomic cation homeostasis,biological_process
67727,GO:0030007,A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell.,intracellular potassium ion homeostasis,biological_process
67728,GO:0030008,A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.,TRAPP complex,cellular_component
67729,GO:0030010,The specification and formation of anisotropic intracellular organization or cell growth patterns.,establishment of cell polarity,biological_process
67730,GO:0030011,The maintenance of established anisotropic intracellular organization or cell growth patterns.,maintenance of cell polarity,biological_process
67731,GO:0030014,"The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.",CCR4-NOT complex,cellular_component
67732,GO:0030015,"The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.",CCR4-NOT core complex,cellular_component
67733,GO:0030016,"The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.",myofibril,cellular_component
67734,GO:0030017,"The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.",sarcomere,cellular_component
67735,GO:0030018,Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.,Z disc,cellular_component
67736,GO:0030020,A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.,extracellular matrix structural constituent conferring tensile strength,molecular_function
67737,GO:0030021,A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.,extracellular matrix structural constituent conferring compression resistance,molecular_function
67738,GO:0030023,A component of the extracellular matrix that enables the matrix to recoil after transient stretching.,extracellular matrix constituent conferring elasticity,molecular_function
67739,GO:0030026,A homeostatic process involved in the maintenance of a steady state level of manganese ions within a cell.,intracellular manganese ion homeostasis,biological_process
67740,GO:0030027,A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.,lamellipodium,cellular_component
67741,GO:0030029,"Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.",actin filament-based process,biological_process
67742,GO:0030030,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.",cell projection organization,biological_process
67743,GO:0030031,"Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.",cell projection assembly,biological_process
67744,GO:0030032,"Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.",lamellipodium assembly,biological_process
67745,GO:0030033,"Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.",microvillus assembly,biological_process
67746,GO:0030034,Assembly of the parallel bundle of actin filaments at the core of a microvillus.,microvillar actin bundle assembly,biological_process
67747,GO:0030035,"Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.",microspike assembly,biological_process
67748,GO:0030036,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.",actin cytoskeleton organization,biological_process
67749,GO:0030038,Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.,contractile actin filament bundle assembly,biological_process
67750,GO:0030041,Assembly of actin filaments by the addition of actin monomers to a filament.,actin filament polymerization,biological_process
67751,GO:0030042,Disassembly of actin filaments by the removal of actin monomers from a filament.,actin filament depolymerization,biological_process
67752,GO:0030043,"The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.",actin filament fragmentation,biological_process
67753,GO:0030046,Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.,parallel actin filament bundle assembly,biological_process
67754,GO:0030047,Covalent modification of an actin molecule.,actin modification,biological_process
67755,GO:0030048,"Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.",actin filament-based movement,biological_process
67756,GO:0030049,The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.,muscle filament sliding,biological_process
67757,GO:0030050,"Movement of a vesicle along an actin filament, mediated by motor proteins.",vesicle transport along actin filament,biological_process
67758,GO:0030054,"A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.",cell junction,cellular_component
67759,GO:0030055,A cell junction that forms a connection between a cell and the extracellular matrix.,cell-substrate junction,cellular_component
67760,GO:0030056,"A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.",hemidesmosome,cellular_component
67761,GO:0030057,A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.,desmosome,cellular_component
67762,GO:0030058,Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.,aliphatic amine dehydrogenase activity,molecular_function
67763,GO:0030059,Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].,aralkylamine dehydrogenase (azurin) activity,molecular_function
67764,GO:0030060,Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.,L-malate dehydrogenase (NAD+) activity,molecular_function
67765,GO:0030061,"Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.",mitochondrial crista,cellular_component
67766,GO:0030070,"The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.",insulin processing,biological_process
67767,GO:0030071,"Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.",regulation of mitotic metaphase/anaphase transition,biological_process
67768,GO:0030072,The regulated release of a peptide hormone from a cell.,peptide hormone secretion,biological_process
67769,GO:0030073,"The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.",insulin secretion,biological_process
67770,GO:0030075,"A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.",bacterial thylakoid,cellular_component
67771,GO:0030076,A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.,light-harvesting complex,cellular_component
67772,GO:0030077,A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.,plasma membrane light-harvesting complex,cellular_component
67773,GO:0030078,Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria.,"light-harvesting complex, core complex",cellular_component
67774,GO:0030079,Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.,"light-harvesting complex, peripheral complex",cellular_component
67775,GO:0030080,Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.,B875 antenna complex,cellular_component
67776,GO:0030081,Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.,B800-820 antenna complex,cellular_component
67777,GO:0030082,Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.,B800-850 antenna complex,cellular_component
67778,GO:0030083,A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.,"PSI associated light-harvesting complex I, LHCIa subcomplex",cellular_component
67779,GO:0030084,A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.,"PSI associated light-harvesting complex I, LHCIb subcomplex",cellular_component
67780,GO:0030085,"A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.","PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex",cellular_component
67781,GO:0030089,"Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.",phycobilisome,cellular_component
67782,GO:0030091,The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.,protein repair,biological_process
67783,GO:0030093,"Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.",chloroplast photosystem I,cellular_component
67784,GO:0030094,"A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.",plasma membrane-derived photosystem I,cellular_component
67785,GO:0030095,"An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.",chloroplast photosystem II,cellular_component
67786,GO:0030096,"A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.",plasma membrane-derived thylakoid photosystem II,cellular_component
67787,GO:0030097,"The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.",hemopoiesis,biological_process
67788,GO:0030098,"The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.",lymphocyte differentiation,biological_process
67789,GO:0030099,"The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.",myeloid cell differentiation,biological_process
67790,GO:0030100,"Any process that modulates the frequency, rate or extent of endocytosis.",regulation of endocytosis,biological_process
67791,GO:0030101,"The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.",natural killer cell activation,biological_process
67792,GO:0030103,The regulated release of vasopressin from secretory granules into the blood.,vasopressin secretion,biological_process
67793,GO:0030107,Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.,HLA-A specific inhibitory MHC class I receptor activity,molecular_function
67794,GO:0030108,Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.,HLA-A specific activating MHC class I receptor activity,molecular_function
67795,GO:0030109,Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.,HLA-B specific inhibitory MHC class I receptor activity,molecular_function
67796,GO:0030110,Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.,HLA-C specific inhibitory MHC class I receptor activity,molecular_function
67797,GO:0030111,"Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.",regulation of Wnt signaling pathway,biological_process
67798,GO:0030112,A carbohydrate rich layer at the outermost periphery of a cell.,glycocalyx,cellular_component
67799,GO:0030114,"A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.",slime layer,cellular_component
67800,GO:0030115,A crystalline protein layer surrounding some bacteria.,S-layer,cellular_component
67801,GO:0030116,A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.,glial cell-derived neurotrophic factor receptor binding,molecular_function
67802,GO:0030117,"Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.",membrane coat,cellular_component
67803,GO:0030118,"A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.",clathrin coat,cellular_component
67804,GO:0030119,"Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).",AP-type membrane coat adaptor complex,cellular_component
67805,GO:0030120,A membrane coat found on a coated vesicle.,vesicle coat,cellular_component
67806,GO:0030121,"A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).",AP-1 adaptor complex,cellular_component
67807,GO:0030122,"A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (...",AP-2 adaptor complex,cellular_component
67808,GO:0030123,"A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).",AP-3 adaptor complex,cellular_component
67809,GO:0030124,"An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.",AP-4 adaptor complex,cellular_component
67810,GO:0030125,A clathrin coat found on a vesicle.,clathrin vesicle coat,cellular_component
67811,GO:0030126,"One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.",COPI vesicle coat,cellular_component
67812,GO:0030127,"One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.",COPII vesicle coat,cellular_component
67813,GO:0030128,A clathrin coat found on an endocytic vesicle.,clathrin coat of endocytic vesicle,cellular_component
67814,GO:0030129,A clathrin coat found on a synaptic vesicle.,clathrin coat of synaptic vesicle,cellular_component
67815,GO:0030130,A clathrin coat found on a vesicle of the trans-Golgi network.,clathrin coat of trans-Golgi network vesicle,cellular_component
67816,GO:0030131,A membrane coat adaptor complex that links clathrin to a membrane.,clathrin adaptor complex,cellular_component
67817,GO:0030132,The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.,clathrin coat of coated pit,cellular_component
67818,GO:0030133,"Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.",transport vesicle,cellular_component
67819,GO:0030134,A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).,COPII-coated ER to Golgi transport vesicle,cellular_component
67820,GO:0030135,"Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.",coated vesicle,cellular_component
67821,GO:0030136,A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.,clathrin-coated vesicle,cellular_component
67822,GO:0030137,"A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.",COPI-coated vesicle,cellular_component
67823,GO:0030139,A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.,endocytic vesicle,cellular_component
67824,GO:0030140,A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.,trans-Golgi network transport vesicle,cellular_component
67825,GO:0030141,"A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.",secretory granule,cellular_component
67826,GO:0030142,A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.,COPI-coated Golgi to ER transport vesicle,cellular_component
67827,GO:0030143,"A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).",COPI-coated inter-Golgi transport vesicle,cellular_component
67828,GO:0030144,"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-ace...","alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity",molecular_function
67829,GO:0030145,Binding to a manganese ion (Mn).,manganese ion binding,molecular_function
67830,GO:0030148,"The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",sphingolipid biosynthetic process,biological_process
67831,GO:0030149,"The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",sphingolipid catabolic process,biological_process
67832,GO:0030150,The import of proteins with mitochondrial targeting sequence from the cytosol across the mitochondrial outer and inner membranes into the matrix via TOM-TIM23-PAM.,protein import into mitochondrial matrix,biological_process
67833,GO:0030151,Binding to a molybdenum ion (Mo).,molybdenum ion binding,molecular_function
67834,GO:0030152,"The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.",bacteriocin biosynthetic process,biological_process
67835,GO:0030153,"A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.",bacteriocin immunity,biological_process
67836,GO:0030154,"The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.",cell differentiation,biological_process
67837,GO:0030155,"Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.",regulation of cell adhesion,biological_process
67838,GO:0030156,Binding to a peripheral benzodiazepine receptor (PBR).,benzodiazepine receptor binding,molecular_function
67839,GO:0030157,"The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.",pancreatic juice secretion,biological_process
67840,GO:0030158,Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.,protein xylosyltransferase activity,molecular_function
67841,GO:0030159,The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.,signaling receptor complex adaptor activity,molecular_function
67842,GO:0030160,The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule.,synaptic receptor adaptor activity,molecular_function
67843,GO:0030162,"Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.",regulation of proteolysis,biological_process
67844,GO:0030163,"The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.",protein catabolic process,biological_process
67845,GO:0030164,"Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.",protein denaturation,biological_process
67846,GO:0030165,"Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.",PDZ domain binding,molecular_function
67847,GO:0030166,"The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",proteoglycan biosynthetic process,biological_process
67848,GO:0030167,"The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",proteoglycan catabolic process,biological_process
67849,GO:0030168,"A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.",platelet activation,biological_process
67850,GO:0030169,"Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.",low-density lipoprotein particle binding,molecular_function
67851,GO:0030170,"Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.",pyridoxal phosphate binding,molecular_function
67852,GO:0030171,Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated proton channel activity,molecular_function
67853,GO:0030172,"Binding to troponin C, the calcium-binding subunit of the troponin complex.",troponin C binding,molecular_function
67854,GO:0030174,"Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.",regulation of DNA-templated DNA replication initiation,biological_process
67855,GO:0030175,"Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.",filopodium,cellular_component
67856,GO:0030177,"Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.",positive regulation of Wnt signaling pathway,biological_process
67857,GO:0030178,"Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.",negative regulation of Wnt signaling pathway,biological_process
67858,GO:0030182,The process in which a relatively unspecialized cell acquires specialized features of a neuron.,neuron differentiation,biological_process
67859,GO:0030183,The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.,B cell differentiation,biological_process
67860,GO:0030184,"Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.",nitric oxide transmembrane transporter activity,molecular_function
67861,GO:0030185,"The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nitric oxide transport,biological_process
67862,GO:0030186,The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).,melatonin metabolic process,biological_process
67863,GO:0030187,The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).,melatonin biosynthetic process,biological_process
67864,GO:0030193,"Any process that modulates the frequency, rate or extent of blood coagulation.",regulation of blood coagulation,biological_process
67865,GO:0030194,"Any process that activates or increases the frequency, rate or extent of blood coagulation.",positive regulation of blood coagulation,biological_process
67866,GO:0030195,"Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.",negative regulation of blood coagulation,biological_process
67867,GO:0030196,Catalysis of the reaction: formamide = H2O + hydrogen cyanide.,cyanide hydratase activity,molecular_function
67868,GO:0030197,"Functions as a lubricant for an extracellular matrix, such as a mucous membrane.","extracellular matrix constituent, lubricant activity",molecular_function
67869,GO:0030198,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.",extracellular matrix organization,biological_process
67870,GO:0030199,Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.,collagen fibril organization,biological_process
67871,GO:0030200,"The chemical reactions and pathways resulting in the breakdown of heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucur...",heparan sulfate proteoglycan catabolic process,biological_process
67872,GO:0030201,"The chemical reactions and pathways involving heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic ...",heparan sulfate proteoglycan metabolic process,biological_process
67873,GO:0030202,"The chemical reactions and pathways involving heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is simi...",heparin proteoglycan metabolic process,biological_process
67874,GO:0030203,"The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units.",glycosaminoglycan metabolic process,biological_process
67875,GO:0030207,"The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate proteoglycans, which consist of a core protein linked to a chondroitin sulfate glycosaminoglycan. The chondroitin sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-glucuronic acid-beta-(1,3)-N-acetyl-D-galactosamine, the latter of which can be O-sulfated.",chondroitin sulfate proteoglycan catabolic process,biological_process
67876,GO:0030209,"The chemical reactions and pathways resulting in the breakdown of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. The former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids and the latter can be O-sulfated.",dermatan sulfate proteoglycan catabolic process,biological_process
67877,GO:0030210,"The chemical reactions and pathways resulting in the formation of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acid...",heparin proteoglycan biosynthetic process,biological_process
67878,GO:0030211,"The chemical reactions and pathways resulting in the breakdown of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids...",heparin proteoglycan catabolic process,biological_process
67879,GO:0030212,"The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine.",hyaluronan metabolic process,biological_process
67880,GO:0030213,"The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine.",hyaluronan biosynthetic process,biological_process
67881,GO:0030214,"The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine.",hyaluronan catabolic process,biological_process
67882,GO:0030215,Binding to a semaphorin receptor.,semaphorin receptor binding,molecular_function
67883,GO:0030216,The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.,keratinocyte differentiation,biological_process
67884,GO:0030217,The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.,T cell differentiation,biological_process
67885,GO:0030218,The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.,erythrocyte differentiation,biological_process
67886,GO:0030219,The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.,megakaryocyte differentiation,biological_process
67887,GO:0030220,The process in which platelets bud from long processes extended by megakaryocytes.,platelet formation,biological_process
67888,GO:0030221,The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.,basophil differentiation,biological_process
67889,GO:0030222,The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.,eosinophil differentiation,biological_process
67890,GO:0030223,The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.,neutrophil differentiation,biological_process
67891,GO:0030224,The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.,monocyte differentiation,biological_process
67892,GO:0030225,The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.,macrophage differentiation,biological_process
67893,GO:0030226,Combining with an apolipoprotein to initiate a change in cell activity.,apolipoprotein receptor activity,molecular_function
67894,GO:0030228,"Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.",lipoprotein particle receptor activity,molecular_function
67895,GO:0030229,Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.,very-low-density lipoprotein particle receptor activity,molecular_function
67896,GO:0030232,"Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.",insulin control element activator complex,cellular_component
67897,GO:0030233,"Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.",deoxynucleotide transmembrane transporter activity,molecular_function
67898,GO:0030234,A molecular function regulator that modulates a catalytic activity.,enzyme regulator activity,molecular_function
67899,GO:0030235,Binds to and modulates the activity of nitric oxide synthase.,nitric-oxide synthase regulator activity,molecular_function
67900,GO:0030237,The specification of female sex of an individual organism.,female sex determination,biological_process
67901,GO:0030238,The specification of male sex of an individual organism.,male sex determination,biological_process
67902,GO:0030239,"Formation of myofibrils, the repeating units of striated muscle.",myofibril assembly,biological_process
67903,GO:0030240,"The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.",skeletal muscle thin filament assembly,biological_process
67904,GO:0030241,"The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.",skeletal muscle myosin thick filament assembly,biological_process
67905,GO:0030242,The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.,autophagy of peroxisome,biological_process
67906,GO:0030243,"The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.",cellulose metabolic process,biological_process
67907,GO:0030244,"The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.",cellulose biosynthetic process,biological_process
67908,GO:0030245,"The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.",cellulose catabolic process,biological_process
67909,GO:0030246,"Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.",carbohydrate binding,molecular_function
67910,GO:0030247,"Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.",polysaccharide binding,molecular_function
67911,GO:0030248,Binding to cellulose.,cellulose binding,molecular_function
67912,GO:0030249,Modulates the activity of guanylate cyclase.,guanylate cyclase regulator activity,molecular_function
67913,GO:0030250,Binds to and increases the activity of guanylate cyclase.,guanylate cyclase activator activity,molecular_function
67914,GO:0030251,"Binds to and stops, prevents or reduces the activity of guanylate cyclase.",guanylate cyclase inhibitor activity,molecular_function
67915,GO:0030252,The regulated release of growth hormone from secretory granules into the blood.,growth hormone secretion,biological_process
67916,GO:0030253,The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.,protein secretion by the type I secretion system,biological_process
67917,GO:0030254,The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.,protein secretion by the type III secretion system,biological_process
67918,GO:0030255,"The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.",protein secretion by the type IV secretion system,biological_process
67919,GO:0030256,"A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.",type I protein secretion system complex,cellular_component
67920,GO:0030257,"A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.",type III protein secretion system complex,cellular_component
67921,GO:0030258,"The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.",lipid modification,biological_process
67922,GO:0030261,"The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.",chromosome condensation,biological_process
67923,GO:0030262,Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.,apoptotic nuclear changes,biological_process
67924,GO:0030263,The compaction of chromatin during apoptosis.,apoptotic chromosome condensation,biological_process
67925,GO:0030264,"The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.",nuclear fragmentation involved in apoptotic nuclear change,biological_process
67926,GO:0030265,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway that starts with an opsin being activated by a photon, and transmitting the signal through the Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). The second messengers, including cGMP, activate channels that result in transmission of the light signal  through the syna...",phospholipase C-activating opsin-mediated signaling pathway,biological_process
67927,GO:0030266,Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.,quinate 3-dehydrogenase (NAD+) activity,molecular_function
67928,GO:0030267,Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.,glyoxylate reductase (NADPH) activity,molecular_function
67929,GO:0030268,"Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H+ = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.",methylenetetrahydromethanopterin dehydrogenase activity,molecular_function
67930,GO:0030269,"Catalysis of the reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na+(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na+(out). 2-(methylthio)ethanesulfonate is also known as methyl-CoM.",tetrahydromethanopterin S-methyltransferase activity,molecular_function
67931,GO:0030270,"Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H+ = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.",formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity,molecular_function
67932,GO:0030272,"Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H+ + phosphate.",5-formyltetrahydrofolate cyclo-ligase activity,molecular_function
67933,GO:0030273,Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.,melanin-concentrating hormone receptor activity,molecular_function
67934,GO:0030274,"Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.",LIM domain binding,molecular_function
67935,GO:0030275,Binding to a LRR domain (leucine rich repeats) of a protein.,LRR domain binding,molecular_function
67936,GO:0030276,"Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.",clathrin binding,molecular_function
67937,GO:0030277,Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.,maintenance of gastrointestinal epithelium,biological_process
67938,GO:0030278,"Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.",regulation of ossification,biological_process
67939,GO:0030279,"Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.",negative regulation of ossification,biological_process
67940,GO:0030280,The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.,structural constituent of skin epidermis,molecular_function
67941,GO:0030281,"The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.",structural constituent of cutaneous appendage,molecular_function
67942,GO:0030282,"The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.",bone mineralization,biological_process
67943,GO:0030284,A nuclear receptor activity regulated by estrogen binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.,nuclear estrogen receptor activity,molecular_function
67944,GO:0030286,"Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.",dynein complex,cellular_component
67945,GO:0030287,The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.,cell wall-bounded periplasmic space,cellular_component
67946,GO:0030288,"The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.",outer membrane-bounded periplasmic space,cellular_component
67947,GO:0030289,A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.,protein phosphatase 4 complex,cellular_component
67948,GO:0030290,"Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.",sphingolipid activator protein activity,molecular_function
67949,GO:0030291,"Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase.",protein serine/threonine kinase inhibitor activity,molecular_function
67950,GO:0030292,"Stops, prevents or reduces the activity of a protein tyrosine kinase.",protein tyrosine kinase inhibitor activity,molecular_function
67951,GO:0030293,"Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.",transmembrane receptor protein tyrosine kinase inhibitor activity,molecular_function
67952,GO:0030294,"Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.",receptor signaling protein tyrosine kinase inhibitor activity,molecular_function
67953,GO:0030295,"Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.",protein kinase activator activity,molecular_function
67954,GO:0030296,"Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.",protein tyrosine kinase activator activity,molecular_function
67955,GO:0030297,Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.,transmembrane receptor protein tyrosine kinase activator activity,molecular_function
67956,GO:0030298,Binds to and increases the activity of a receptor signaling protein tyrosine kinase.,receptor signaling protein tyrosine kinase activator activity,molecular_function
67957,GO:0030299,Uptake of cholesterol into the blood by absorption from the small intestine.,intestinal cholesterol absorption,biological_process
67958,GO:0030300,"Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.",regulation of intestinal cholesterol absorption,biological_process
67959,GO:0030301,"The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cholesterol transport,biological_process
67960,GO:0030302,"The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.",deoxynucleotide transport,biological_process
67961,GO:0030305,Catalysis of the endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan.,heparanase activity,molecular_function
67962,GO:0030307,"Any process that activates or increases the frequency, rate, extent or direction of cell growth.",positive regulation of cell growth,biological_process
67963,GO:0030308,"Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.",negative regulation of cell growth,biological_process
67964,GO:0030309,"The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.",poly-N-acetyllactosamine metabolic process,biological_process
67965,GO:0030310,"The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.",poly-N-acetyllactosamine catabolic process,biological_process
67966,GO:0030311,"The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.",poly-N-acetyllactosamine biosynthetic process,biological_process
67967,GO:0030312,A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.,external encapsulating structure,cellular_component
67968,GO:0030313,"An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.",cell envelope,cellular_component
67969,GO:0030314,Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).,junctional membrane complex,cellular_component
67970,GO:0030315,Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.,T-tubule,cellular_component
67971,GO:0030316,The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.,osteoclast differentiation,biological_process
67972,GO:0030317,"The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.",flagellated sperm motility,biological_process
67973,GO:0030318,The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.,melanocyte differentiation,biological_process
67974,GO:0030321,The directed movement of chloride ions from one side of an epithelium to the other.,transepithelial chloride transport,biological_process
67975,GO:0030322,"The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",stabilization of membrane potential,biological_process
67976,GO:0030323,"The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.",respiratory tube development,biological_process
67977,GO:0030324,"The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and m...",lung development,biological_process
67978,GO:0030325,"The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.",adrenal gland development,biological_process
67979,GO:0030326,"The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.",embryonic limb morphogenesis,biological_process
67980,GO:0030327,The chemical reactions and pathways resulting in the breakdown of prenylated proteins.,prenylated protein catabolic process,biological_process
67981,GO:0030328,"The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.",prenylcysteine catabolic process,biological_process
67982,GO:0030330,"A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.","DNA damage response, signal transduction by p53 class mediator",biological_process
67983,GO:0030331,Binding to a nuclear estrogen receptor.,nuclear estrogen receptor binding,molecular_function
67984,GO:0030332,"Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.",cyclin binding,molecular_function
67985,GO:0030334,"Any process that modulates the frequency, rate or extent of cell migration.",regulation of cell migration,biological_process
67986,GO:0030335,"Any process that activates or increases the frequency, rate or extent of cell migration.",positive regulation of cell migration,biological_process
67987,GO:0030336,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.",negative regulation of cell migration,biological_process
67988,GO:0030337,"An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.",DNA polymerase processivity factor activity,molecular_function
67989,GO:0030338,Catalysis of the reaction: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O.,CMP-N-acetylneuraminate monooxygenase activity,molecular_function
67990,GO:0030339,Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.,fatty-acyl-ethyl-ester synthase activity,molecular_function
67991,GO:0030340,Catalysis of the reaction: hyaluronate(n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O.,hyaluronate lyase activity,molecular_function
67992,GO:0030341,"Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.",chondroitin AC lyase activity,molecular_function
67993,GO:0030342,"Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).","1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity",molecular_function
67994,GO:0030343,Catalysis of the reaction: calciol (vitamin D3) + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H+.,vitamin D 25-hydroxylase activity,molecular_function
67995,GO:0030345,The action of a molecule that contributes to the structural integrity of tooth enamel.,structural constituent of tooth enamel,molecular_function
67996,GO:0030346,Binding to a protein phosphatase 2B.,protein phosphatase 2B binding,molecular_function
67997,GO:0030348,Binding to a syntaxin-3 SNAP receptor.,syntaxin-3 binding,molecular_function
67998,GO:0030350,"Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.",iron-responsive element binding,molecular_function
67999,GO:0030351,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate.","inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity",molecular_function
68000,GO:0030352,"Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.","inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity",molecular_function
68001,GO:0030353,"Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.",fibroblast growth factor receptor antagonist activity,molecular_function
68002,GO:0030354,"The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.",melanin-concentrating hormone activity,molecular_function
68003,GO:0030366,"Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.",molybdopterin synthase activity,molecular_function
68004,GO:0030367,Binding to an interleukin-17 receptor.,interleukin-17 receptor binding,molecular_function
68005,GO:0030368,Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-17 receptor activity,molecular_function
68006,GO:0030370,"Binding to a receptor for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.",intercellular adhesion molecule-3 receptor binding,molecular_function
68007,GO:0030371,Antagonizes ribosome-mediated translation of mRNA into a polypeptide.,translation repressor activity,molecular_function
68008,GO:0030372,Binding to a high molecular weight B cell growth factor receptor.,high molecular weight B cell growth factor receptor binding,molecular_function
68009,GO:0030373,Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.,high molecular weight B cell growth factor receptor activity,molecular_function
68010,GO:0030377,Combining with the urokinase plasminogen activator to initiate a change in cell activity.,urokinase plasminogen activator receptor activity,molecular_function
68011,GO:0030378,Catalysis of the reaction: L-serine = D-serine.,serine racemase activity,molecular_function
68012,GO:0030379,"Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.","neurotensin receptor activity, non-G protein-coupled",molecular_function
68013,GO:0030380,Binding to an interleukin-17E receptor.,interleukin-17E receptor binding,molecular_function
68014,GO:0030381,The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.,chorion-containing eggshell pattern formation,biological_process
68015,GO:0030382,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.",sperm mitochondrion organization,biological_process
68016,GO:0030386,A protein complex that possesses ferredoxin-thioredoxin reductase activity.,ferredoxin-thioredoxin reductase complex,cellular_component
68017,GO:0030388,"The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.","fructose 1,6-bisphosphate metabolic process",biological_process
68018,GO:0030389,"The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.",fructosamine metabolic process,biological_process
68019,GO:0030391,"The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.",fructosamine biosynthetic process,biological_process
68020,GO:0030392,"The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.",fructosamine catabolic process,biological_process
68021,GO:0030393,"The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.",fructoselysine metabolic process,biological_process
68022,GO:0030395,"Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.",lactose binding,molecular_function
68023,GO:0030397,The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.,membrane disassembly,biological_process
68024,GO:0030399,The controlled breakdown of the membranes of autophagosomes.,autophagosome membrane disassembly,biological_process
68025,GO:0030408,"Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.",glycine formimidoyltransferase activity,molecular_function
68026,GO:0030409,Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.,glutamate formimidoyltransferase activity,molecular_function
68027,GO:0030410,Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H+ + nicotianamine.,nicotianamine synthase activity,molecular_function
68028,GO:0030411,"Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H2O.",scytalone dehydratase activity,molecular_function
68029,GO:0030412,"Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H+ = 5,10-methenyltetrahydrofolate + NH4.",formimidoyltetrahydrofolate cyclodeaminase activity,molecular_function
68030,GO:0030413,A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.,competence pheromone activity,molecular_function
68031,GO:0030414,"Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.",peptidase inhibitor activity,molecular_function
68032,GO:0030416,The chemical reactions and pathways involving methylamine (CH3NH2).,methylamine metabolic process,biological_process
68033,GO:0030418,The chemical reactions and pathways resulting in the formation of nicotianamine.,nicotianamine biosynthetic process,biological_process
68034,GO:0030420,"The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.",establishment of competence for transformation,biological_process
68035,GO:0030421,The expulsion of feces from the rectum.,defecation,biological_process
68036,GO:0030422,A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase.,siRNA processing,biological_process
68037,GO:0030424,"The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.",axon,cellular_component
68038,GO:0030425,"A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.",dendrite,cellular_component
68039,GO:0030426,"The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.",growth cone,cellular_component
68040,GO:0030427,Any part of a cell where non-isotropic growth takes place.,site of polarized growth,cellular_component
68041,GO:0030428,A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.,cell septum,cellular_component
68042,GO:0030429,Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine + H+. Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)- alanines.,kynureninase activity,molecular_function
68043,GO:0030430,The cytoplasm of a host cell.,host cell cytoplasm,cellular_component
68044,GO:0030431,"Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.",sleep,biological_process
68045,GO:0030432,"A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.",peristalsis,biological_process
68046,GO:0030435,"The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.",sporulation resulting in formation of a cellular spore,biological_process
68047,GO:0030436,The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.,asexual sporulation,biological_process
68048,GO:0030437,"The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).",ascospore formation,biological_process
68049,GO:0030445,"The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.",yeast-form cell wall,cellular_component
68050,GO:0030446,The cell wall surrounding a fungal hypha.,hyphal cell wall,cellular_component
68051,GO:0030447,"The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.",filamentous growth,biological_process
68052,GO:0030448,"Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.",hyphal growth,biological_process
68053,GO:0030449,"Any process that modulates the frequency, rate or extent of complement activation.",regulation of complement activation,biological_process
68054,GO:0030450,"Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.","regulation of complement activation, classical pathway",biological_process
68055,GO:0030451,"Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.","regulation of complement activation, alternative pathway",biological_process
68056,GO:0030466,Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.,silent mating-type cassette heterochromatin formation,biological_process
68057,GO:0030473,"The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.",nuclear migration along microtubule,biological_process
68058,GO:0030474,Construction of a new spindle pole body.,spindle pole body duplication,biological_process
68059,GO:0030476,"The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.",ascospore wall assembly,biological_process
68060,GO:0030478,Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.,actin cap,cellular_component
68061,GO:0030479,"An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.",actin cortical patch,cellular_component
68062,GO:0030485,The contractile fiber of smooth muscle cells.,smooth muscle contractile fiber,cellular_component
68063,GO:0030486,Electron-dense region associated with a smooth muscle contractile fiber.,smooth muscle dense body,cellular_component
68064,GO:0030487,"Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.","inositol-4,5-bisphosphate 5-phosphatase activity",molecular_function
68065,GO:0030488,The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.,tRNA methylation,biological_process
68066,GO:0030490,Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.,maturation of SSU-rRNA,biological_process
68067,GO:0030491,The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.,heteroduplex formation,biological_process
68068,GO:0030492,"Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.",hemoglobin binding,molecular_function
68069,GO:0030494,"The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.",bacteriochlorophyll biosynthetic process,biological_process
68070,GO:0030495,"The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.",bacteriochlorophyll catabolic process,biological_process
68071,GO:0030496,"A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.",midbody,cellular_component
68072,GO:0030497,The elongation of a fatty acid chain by the sequential addition of two-carbon units.,fatty acid elongation,biological_process
68073,GO:0030500,"Any process that modulates the frequency, rate or extent of bone mineralization.",regulation of bone mineralization,biological_process
68074,GO:0030501,"Any process that activates or increases the frequency, rate or extent of bone mineralization.",positive regulation of bone mineralization,biological_process
68075,GO:0030502,"Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.",negative regulation of bone mineralization,biological_process
68076,GO:0030505,"The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",inorganic diphosphate transport,biological_process
68077,GO:0030506,"Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.",ankyrin binding,molecular_function
68078,GO:0030507,"Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.",spectrin binding,molecular_function
68079,GO:0030509,"The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",BMP signaling pathway,biological_process
68080,GO:0030510,"Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.",regulation of BMP signaling pathway,biological_process
68081,GO:0030511,"Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.",positive regulation of transforming growth factor beta receptor signaling pathway,biological_process
68082,GO:0030512,"Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.",negative regulation of transforming growth factor beta receptor signaling pathway,biological_process
68083,GO:0030513,"Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.",positive regulation of BMP signaling pathway,biological_process
68084,GO:0030514,"Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.",negative regulation of BMP signaling pathway,biological_process
68085,GO:0030515,Binding to a small nucleolar RNA.,snoRNA binding,molecular_function
68086,GO:0030516,"Any process that modulates the rate, direction or extent of axon extension.",regulation of axon extension,biological_process
68087,GO:0030517,"Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.",negative regulation of axon extension,biological_process
68088,GO:0030518,"A nuclear receptor-mediated signaling pathway initiated by a steroid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated steroid hormone signaling pathway,biological_process
68089,GO:0030519,Binding to a small nucleolar ribonucleoprotein particle.,snoRNP binding,molecular_function
68090,GO:0030520,"A nuclear receptor-mediated signaling pathway initiated by an estrogen binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",estrogen receptor signaling pathway,biological_process
68091,GO:0030521,"A nuclear receptor-mediated signaling pathway initiated by an androgen binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",androgen receptor signaling pathway,biological_process
68092,GO:0030522,The series of molecular signals initiated by a ligand binding to a receptor located within a cell.,intracellular receptor signaling pathway,biological_process
68093,GO:0030526,The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.,granulocyte macrophage colony-stimulating factor receptor complex,cellular_component
68094,GO:0030527,The action of a molecule that contributes to the structural integrity of chromatin.,structural constituent of chromatin,molecular_function
68095,GO:0030532,"A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs.",small nuclear ribonucleoprotein complex,cellular_component
68096,GO:0030533,"The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.",triplet codon-amino acid adaptor activity,molecular_function
68097,GO:0030534,Behavior in a fully developed and mature organism.,adult behavior,biological_process
68098,GO:0030536,Feeding behavior in a larval (immature) organism.,larval feeding behavior,biological_process
68099,GO:0030537,"Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.",larval behavior,biological_process
68100,GO:0030538,"The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.",embryonic genitalia morphogenesis,biological_process
68101,GO:0030539,"The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.",male genitalia development,biological_process
68102,GO:0030540,"The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.",female genitalia development,biological_process
68103,GO:0030541,Any process in which plasmids are segregated or distributed into daughter cells upon cell division.,plasmid partitioning,biological_process
68104,GO:0030543,"The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.",2-micrometer plasmid partitioning,biological_process
68105,GO:0030544,"Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.",Hsp70 protein binding,molecular_function
68106,GO:0030545,Binds to and modulates the activity of a receptor.,signaling receptor regulator activity,molecular_function
68107,GO:0030546,The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.,signaling receptor activator activity,molecular_function
68108,GO:0030547,Binds to and modulates the activity of a signaling receptor.,signaling receptor inhibitor activity,molecular_function
68109,GO:0030548,Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.,acetylcholine receptor regulator activity,molecular_function
68110,GO:0030549,Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.,acetylcholine receptor activator activity,molecular_function
68111,GO:0030550,"Binds to and stops, prevents or reduces the activity of an acetylcholine receptor.",acetylcholine receptor inhibitor activity,molecular_function
68112,GO:0030551,"Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.",cyclic nucleotide binding,molecular_function
68113,GO:0030552,"Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).",cAMP binding,molecular_function
68114,GO:0030553,"Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).",cGMP binding,molecular_function
68115,GO:0030554,"Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.",adenyl nucleotide binding,molecular_function
68116,GO:0030555,Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.,RNA modification guide activity,molecular_function
68117,GO:0030556,Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.,rRNA modification guide activity,molecular_function
68118,GO:0030557,Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.,tRNA modification guide activity,molecular_function
68119,GO:0030558,Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.,RNA pseudouridylation guide activity,molecular_function
68120,GO:0030559,Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.,rRNA pseudouridylation guide activity,molecular_function
68121,GO:0030560,Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.,tRNA pseudouridylation guide activity,molecular_function
68122,GO:0030561,Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.,RNA 2'-O-ribose methylation guide activity,molecular_function
68123,GO:0030562,Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.,rRNA 2'-O-ribose methylation guide activity,molecular_function
68124,GO:0030563,Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.,snRNA 2'-O-ribose methylation guide activity,molecular_function
68125,GO:0030564,Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.,tRNA 2'-O-ribose methylation guide activity,molecular_function
68126,GO:0030565,Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.,snRNA pseudouridylation guide activity,molecular_function
68127,GO:0030566,Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.,snRNA modification guide activity,molecular_function
68128,GO:0030570,Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.,pectate lyase activity,molecular_function
68129,GO:0030572,Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.,phosphatidyltransferase activity,molecular_function
68130,GO:0030573,"The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.",bile acid catabolic process,biological_process
68131,GO:0030574,"The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.",collagen catabolic process,biological_process
68132,GO:0030575,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.",nuclear body organization,biological_process
68133,GO:0030576,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.",Cajal body organization,biological_process
68134,GO:0030577,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.",Lands organization,biological_process
68135,GO:0030578,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).",PML body organization,biological_process
68136,GO:0030581,The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont intracellular protein transport in host,biological_process
68137,GO:0030582,"The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.",reproductive fruiting body development,biological_process
68138,GO:0030583,"The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.",myxococcal fruiting body development,biological_process
68139,GO:0030584,"The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.",sporocarp development,biological_process
68140,GO:0030585,Catalysis of the reaction: diphosphate + oxaloacetate = CO2 + phosphate + phosphoenolpyruvate.,phosphoenolpyruvate carboxykinase (diphosphate) activity,molecular_function
68141,GO:0030586,Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.,[methionine synthase] reductase (NADPH) activity,molecular_function
68142,GO:0030587,"The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.",sorocarp development,biological_process
68143,GO:0030588,Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.,pseudocleavage,biological_process
68144,GO:0030589,Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.,pseudocleavage involved in syncytial blastoderm formation,biological_process
68145,GO:0030590,"A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.",first cell cycle pseudocleavage,biological_process
68146,GO:0030591,Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.,2'-deoxyguanosine DNA ADP-ribosyltransferase activity,molecular_function
68147,GO:0030592,The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.,DNA ADP-ribosylation,biological_process
68148,GO:0030593,"The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.",neutrophil chemotaxis,biological_process
68149,GO:0030594,Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.,neurotransmitter receptor activity,molecular_function
68150,GO:0030595,The movement of a leukocyte in response to an external stimulus.,leukocyte chemotaxis,biological_process
68151,GO:0030596,Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.,alpha-L-rhamnosidase activity,molecular_function
68152,GO:0030597,Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule.,RNA glycosylase activity,molecular_function
68153,GO:0030598,Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.,rRNA N-glycosylase activity,molecular_function
68154,GO:0030599,Catalysis of the reaction: pectin + n H2O = n methanol + pectate.,pectinesterase activity,molecular_function
68155,GO:0030600,Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.,feruloyl esterase activity,molecular_function
68156,GO:0030603,Catalysis of the reaction: H2O + oxaloacetate = acetate + H+ + oxalate.,oxaloacetase activity,molecular_function
68157,GO:0030604,Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + H+ + NADPH.,1-deoxy-D-xylulose-5-phosphate reductoisomerase activity,molecular_function
68158,GO:0030611,Catalysis of the reaction: arsenite + A + H2O = arsenate + AH2 + H+.,arsenate reductase activity,molecular_function
68159,GO:0030612,Catalysis of the reaction: arsenate + [thioredoxin]-dithiol + H+ = arsenite + [thioredoxin]-disulfide + H2O.,arsenate reductase (thioredoxin) activity,molecular_function
68160,GO:0030613,Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.,"oxidoreductase activity, acting on phosphorus or arsenic in donors",molecular_function
68161,GO:0030614,Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.,"oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor",molecular_function
68162,GO:0030619,Binding to a U1 small nuclear RNA (U1 snRNA).,U1 snRNA binding,molecular_function
68163,GO:0030620,Binding to a U2 small nuclear RNA (U2 snRNA).,U2 snRNA binding,molecular_function
68164,GO:0030621,Binding to a U4 small nuclear RNA (U4 snRNA).,U4 snRNA binding,molecular_function
68165,GO:0030622,Binding to a U4atac small nuclear RNA (U4atac snRNA).,U4atac snRNA binding,molecular_function
68166,GO:0030623,Binding to a U5 small nuclear RNA (U5 snRNA).,U5 snRNA binding,molecular_function
68167,GO:0030624,Binding to a U6atac small nuclear RNA (U6atac snRNA).,U6atac snRNA binding,molecular_function
68168,GO:0030625,Binding to a U11 small nuclear RNA (U11 snRNA).,U11 snRNA binding,molecular_function
68169,GO:0030626,Binding to a U12 small nuclear RNA (U12 snRNA).,U12 snRNA binding,molecular_function
68170,GO:0030627,Binding to a pre-mRNA 5' splice site sequence.,pre-mRNA 5'-splice site binding,molecular_function
68171,GO:0030628,Binding to a pre-mRNA 3' splice site sequence.,pre-mRNA 3'-splice site binding,molecular_function
68172,GO:0030629,Binding to a U6 small nuclear RNA (U6 snRNA) at the 3' end.,U6 snRNA 3'-end binding,molecular_function
68173,GO:0030631,"The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.",pyrrolysine incorporation,biological_process
68174,GO:0030632,"The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.",D-alanine biosynthetic process,biological_process
68175,GO:0030634,A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).,carbon fixation by acetyl-CoA pathway,biological_process
68176,GO:0030638,"The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.",polyketide metabolic process,biological_process
68177,GO:0030639,"The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.",polyketide biosynthetic process,biological_process
68178,GO:0030640,"The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.",polyketide catabolic process,biological_process
68179,GO:0030642,A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell.,intracellular sulfate ion homeostasis,biological_process
68180,GO:0030643,A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell.,intracellular phosphate ion homeostasis,biological_process
68181,GO:0030644,A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell.,intracellular chloride ion homeostasis,biological_process
68182,GO:0030645,"The anaerobic chemical reactions and pathways resulting in the breakdown of acetyl-CoA to butyrate, yielding energy in the form of ATP. Butanoate is secreted by the cell.",acetyl-CoA fermentation to butanoate,biological_process
68183,GO:0030648,"The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.",aminoglycoside antibiotic biosynthetic process,biological_process
68184,GO:0030649,"The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.",aminoglycoside antibiotic catabolic process,biological_process
68185,GO:0030651,The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.,peptide antibiotic biosynthetic process,biological_process
68186,GO:0030652,The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.,peptide antibiotic catabolic process,biological_process
68187,GO:0030654,"The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.",beta-lactam antibiotic biosynthetic process,biological_process
68188,GO:0030655,"The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.",beta-lactam antibiotic catabolic process,biological_process
68189,GO:0030656,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",regulation of vitamin metabolic process,biological_process
68190,GO:0030658,The lipid bilayer surrounding a transport vesicle.,transport vesicle membrane,cellular_component
68191,GO:0030659,The lipid bilayer surrounding a cytoplasmic vesicle.,cytoplasmic vesicle membrane,cellular_component
68192,GO:0030660,The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.,Golgi-associated vesicle membrane,cellular_component
68193,GO:0030661,The lipid bilayer surrounding a chitosome.,chitosome membrane,cellular_component
68194,GO:0030662,The lipid bilayer surrounding a coated vesicle.,coated vesicle membrane,cellular_component
68195,GO:0030663,The lipid bilayer surrounding a COPI-coated vesicle.,COPI-coated vesicle membrane,cellular_component
68196,GO:0030665,The lipid bilayer surrounding a clathrin-coated vesicle.,clathrin-coated vesicle membrane,cellular_component
68197,GO:0030666,The lipid bilayer surrounding an endocytic vesicle.,endocytic vesicle membrane,cellular_component
68198,GO:0030667,The lipid bilayer surrounding a secretory granule.,secretory granule membrane,cellular_component
68199,GO:0030668,The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.,apicomplexan dense granule membrane,cellular_component
68200,GO:0030669,The lipid bilayer surrounding a clathrin-coated endocytic vesicle.,clathrin-coated endocytic vesicle membrane,cellular_component
68201,GO:0030670,The lipid bilayer surrounding a phagocytic vesicle.,phagocytic vesicle membrane,cellular_component
68202,GO:0030671,The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.,clathrin-coated phagocytic vesicle membrane,cellular_component
68203,GO:0030672,The lipid bilayer surrounding a synaptic vesicle.,synaptic vesicle membrane,cellular_component
68204,GO:0030673,"The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.",axolemma,cellular_component
68205,GO:0030674,"An adaptor activity that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.",protein-macromolecule adaptor activity,molecular_function
68206,GO:0030677,"A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.",ribonuclease P complex,cellular_component
68207,GO:0030678,"A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.",mitochondrial ribonuclease P complex,cellular_component
68208,GO:0030679,"A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.",cyanelle ribonuclease P complex,cellular_component
68209,GO:0030680,"A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.",dimeric ribonuclease P complex,cellular_component
68210,GO:0030681,A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.,multimeric ribonuclease P complex,cellular_component
68211,GO:0030682,A process in which a symbiont alters or subverts the normal execution of a host organism's defense response. The host defense response is mounted by the host in response to the presence of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host defenses,biological_process
68212,GO:0030684,"Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.",preribosome,cellular_component
68213,GO:0030686,"A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.",90S preribosome,cellular_component
68214,GO:0030687,"A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.","preribosome, large subunit precursor",cellular_component
68215,GO:0030688,"A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.","preribosome, small subunit precursor",cellular_component
68216,GO:0030689,"Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.",Noc complex,cellular_component
68217,GO:0030690,"A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.",Noc1p-Noc2p complex,cellular_component
68218,GO:0030691,"A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.",Noc2p-Noc3p complex,cellular_component
68219,GO:0030692,"A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.",Noc4p-Nop14p complex,cellular_component
68220,GO:0030694,"The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.","bacterial-type flagellum basal body, rod",cellular_component
68221,GO:0030695,Binds to and modulates the activity of a GTPase.,GTPase regulator activity,molecular_function
68222,GO:0030697,Catalysis of the reaction: S-adenosyl-L-methionine + uridine54 in tRNA = 5-methyluridine54 in tRNA + H+ + S-adenosyl-L-homocysteine.,"tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent",molecular_function
68223,GO:0030699,Catalysis of the reaction: acetyl phosphate + H2O + NH4 + thioredoxin disulfide = glycine + H+ + phosphate + thioredoxin.,glycine reductase activity,molecular_function
68224,GO:0030700,"Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.",glycine reductase complex,cellular_component
68225,GO:0030701,Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].,NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity,molecular_function
68226,GO:0030703,"Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.",eggshell formation,biological_process
68227,GO:0030704,"Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.",vitelline membrane formation,biological_process
68228,GO:0030705,The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.,cytoskeleton-dependent intracellular transport,biological_process
68229,GO:0030706,The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.,germarium-derived oocyte differentiation,biological_process
68230,GO:0030707,"The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.",follicle cell of egg chamber development,biological_process
68231,GO:0030708,Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.,germarium-derived female germ-line cyst encapsulation,biological_process
68232,GO:0030709,"The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.",border follicle cell delamination,biological_process
68233,GO:0030710,"Any process that regulates the frequency, rate or extent of border cell delamination.",regulation of border follicle cell delamination,biological_process
68234,GO:0030711,"Any process that increases the frequency, rate or extent of border cell delamination.",positive regulation of border follicle cell delamination,biological_process
68235,GO:0030712,"Any process that decreases the frequency, rate or extent of border cell delamination.",negative regulation of border follicle cell delamination,biological_process
68236,GO:0030713,Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.,follicle cell of egg chamber stalk formation,biological_process
68237,GO:0030714,Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.,"anterior/posterior axis specification, follicular epithelium",biological_process
68238,GO:0030715,"The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.",oocyte growth in germarium-derived egg chamber,biological_process
68239,GO:0030716,"The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.",oocyte fate determination,biological_process
68240,GO:0030717,The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.,oocyte karyosome formation,biological_process
68241,GO:0030718,Any process by which an organism or tissue maintains a population of germ-line stem cells.,germ-line stem cell population maintenance,biological_process
68242,GO:0030719,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.",P granule organization,biological_process
68243,GO:0030720,"Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.",oocyte localization involved in germarium-derived egg chamber formation,biological_process
68244,GO:0030721,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.",spectrosome organization,biological_process
68245,GO:0030723,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.",ovarian fusome organization,biological_process
68246,GO:0030724,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.",testicular fusome organization,biological_process
68247,GO:0030725,Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.,germline ring canal formation,biological_process
68248,GO:0030726,Formation of the intercellular bridges that connect the germ-line cells of a male cyst.,male germline ring canal formation,biological_process
68249,GO:0030727,"Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.",germarium-derived female germ-line cyst formation,biological_process
68250,GO:0030728,The release of a mature ovum/oocyte from an ovary.,ovulation,biological_process
68251,GO:0030729,Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.,acetoacetate-CoA ligase activity,molecular_function
68252,GO:0030730,The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.,triglyceride storage,biological_process
68253,GO:0030731,Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H+.,guanidinoacetate N-methyltransferase activity,molecular_function
68254,GO:0030732,Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.,methionine S-methyltransferase activity,molecular_function
68255,GO:0030733,Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.,fatty acid O-methyltransferase activity,molecular_function
68256,GO:0030734,"Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.",polysaccharide O-methyltransferase activity,molecular_function
68257,GO:0030735,Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H+.,carnosine N-methyltransferase activity,molecular_function
68258,GO:0030736,Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H+.,phenol O-methyltransferase activity,molecular_function
68259,GO:0030737,Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H+.,iodophenol O-methyltransferase activity,molecular_function
68260,GO:0030738,Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H+.,tyramine N-methyltransferase activity,molecular_function
68261,GO:0030739,Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.,O-demethylpuromycin O-methyltransferase activity,molecular_function
68262,GO:0030740,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.,inositol 3-methyltransferase activity,molecular_function
68263,GO:0030741,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.,inositol 1-methyltransferase activity,molecular_function
68264,GO:0030742,Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state.,GTP-dependent protein binding,molecular_function
68265,GO:0030743,Catalysis of the reaction: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(1067) in 23S rRNA + H+ + S-adenosyl-L-homocysteine.,23S rRNA (adenosine(1067)-2'-O-ribose)-methyltransferase activity,molecular_function
68266,GO:0030746,Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.,isoflavone 4'-O-methyltransferase activity,molecular_function
68267,GO:0030747,Catalysis of the reaction: indole-3-pyruvate + S-adenosyl-L-methionine = (R)-3-(indol-3-yl)-2-oxobutanoate + H+ + S-adenosyl-L-homocysteine.,indolepyruvate C-methyltransferase activity,molecular_function
68268,GO:0030748,"Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine. Acts on primary, secondary and tertiary amines.",amine N-methyltransferase activity,molecular_function
68269,GO:0030749,Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.,loganate O-methyltransferase activity,molecular_function
68270,GO:0030750,Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H+.,putrescine N-methyltransferase activity,molecular_function
68271,GO:0030751,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H+.,licodione 2'-O-methyltransferase activity,molecular_function
68272,GO:0030752,Catalysis of the reaction: a 5-hydroxyfurocoumarin + S-adenosyl-L-methionine = a 5-methoxyfurocoumarin + S-adenosyl-L-homocysteine + H+.,5-hydroxyfuranocoumarin 5-O-methyltransferase activity,molecular_function
68273,GO:0030753,Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.,8-hydroxyfuranocoumarin 8-O-methyltransferase activity,molecular_function
68274,GO:0030754,"Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.",apigenin 4'-O-methyltransferase activity,molecular_function
68275,GO:0030755,"Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.",quercetin 3-O-methyltransferase activity,molecular_function
68276,GO:0030756,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H+ + isoscoparin.,isoorientin 3'-O-methyltransferase activity,molecular_function
68277,GO:0030757,"Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.",3-methylquercitin 7-O-methyltransferase activity,molecular_function
68278,GO:0030758,"Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.","3,7-dimethylquercitin 4'-O-methyltransferase activity",molecular_function
68279,GO:0030759,"Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.",methylquercetagetin 6-O-methyltransferase activity,molecular_function
68280,GO:0030760,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.,pyridine N-methyltransferase activity,molecular_function
68281,GO:0030761,"Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H+.",8-hydroxyquercitin 8-O-methyltransferase activity,molecular_function
68282,GO:0030762,Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H+ + tetrahydropalmatine.,tetrahydrocolumbamine 2-O-methyltransferase activity,molecular_function
68283,GO:0030763,Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H+.,isobutyraldoxime O-methyltransferase activity,molecular_function
68284,GO:0030766,Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.,11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity,molecular_function
68285,GO:0030767,Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H+.,3-hydroxyanthranilate 4-C-methyltransferase activity,molecular_function
68286,GO:0030768,"Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H+.","16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity",molecular_function
68287,GO:0030769,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H+ + tylosin.,macrocin O-methyltransferase activity,molecular_function
68288,GO:0030770,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H+ + macrocin.,demethylmacrocin O-methyltransferase activity,molecular_function
68289,GO:0030771,Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H+.,N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity,molecular_function
68290,GO:0030772,Catalysis of the reaction: L-tryptophan + S-adenosyl-L-methionine = 2-methyl-L-tryptophan + S-adenosyl-L-homocysteine + H+.,tryptophan 2-C-methyltransferase activity,molecular_function
68291,GO:0030773,Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H+.,6-hydroxymellein O-methyltransferase activity,molecular_function
68292,GO:0030774,Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H+.,anthranilate N-methyltransferase activity,molecular_function
68293,GO:0030775,Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.,glucuronoxylan 4-O-methyltransferase activity,molecular_function
68294,GO:0030776,"Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.","(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity",molecular_function
68295,GO:0030777,Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H+.,(S)-scoulerine 9-O-methyltransferase activity,molecular_function
68296,GO:0030778,Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H+ + palmatine.,columbamine O-methyltransferase activity,molecular_function
68297,GO:0030779,Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H+.,10-hydroxydihydrosanguinarine 10-O-methyltransferase activity,molecular_function
68298,GO:0030780,Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H+.,12-hydroxydihydrochelirubine 12-O-methyltransferase activity,molecular_function
68299,GO:0030781,Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.,6-O-methylnorlaudanosoline 5'-O-methyltransferase activity,molecular_function
68300,GO:0030782,"Catalysis of the reaction: an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine = an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine.",(S)-tetrahydroprotoberberine N-methyltransferase activity,molecular_function
68301,GO:0030783,Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.,[cytochrome c]-methionine S-methyltransferase activity,molecular_function
68302,GO:0030784,Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.,3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity,molecular_function
68303,GO:0030785,"Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.",[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity,molecular_function
68304,GO:0030786,Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.,(RS)-norcoclaurine 6-O-methyltransferase activity,molecular_function
68305,GO:0030787,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.,inositol 4-methyltransferase activity,molecular_function
68306,GO:0030788,Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H+ + precorrin-3A.,precorrin-2 C20-methyltransferase activity,molecular_function
68307,GO:0030789,Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.,precorrin-3B C17-methyltransferase activity,molecular_function
68308,GO:0030790,Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.,chlorophenol O-methyltransferase activity,molecular_function
68309,GO:0030791,Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.,arsenite methyltransferase activity,molecular_function
68310,GO:0030793,Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H+ + staurosporine.,3'-demethylstaurosporine O-methyltransferase activity,molecular_function
68311,GO:0030794,Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.,(S)-coclaurine-N-methyltransferase activity,molecular_function
68312,GO:0030795,Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate.,methyl jasmonate methylesterase activity,molecular_function
68313,GO:0030796,Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H+.,cycloartenol 24-C-methyltransferase activity,molecular_function
68314,GO:0030797,Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H+.,24-methylenesterol C-methyltransferase activity,molecular_function
68315,GO:0030798,Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.,trans-aconitate 2-methyltransferase activity,molecular_function
68316,GO:0030805,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.",regulation of cyclic nucleotide catabolic process,biological_process
68317,GO:0030808,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.",regulation of nucleotide biosynthetic process,biological_process
68318,GO:0030809,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.",negative regulation of nucleotide biosynthetic process,biological_process
68319,GO:0030810,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.",positive regulation of nucleotide biosynthetic process,biological_process
68320,GO:0030811,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.",regulation of nucleotide catabolic process,biological_process
68321,GO:0030812,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.",negative regulation of nucleotide catabolic process,biological_process
68322,GO:0030813,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.",positive regulation of nucleotide catabolic process,biological_process
68323,GO:0030832,Any process that controls the length of actin filaments in a cell.,regulation of actin filament length,biological_process
68324,GO:0030833,"Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.",regulation of actin filament polymerization,biological_process
68325,GO:0030834,"Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.",regulation of actin filament depolymerization,biological_process
68326,GO:0030835,"Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.",negative regulation of actin filament depolymerization,biological_process
68327,GO:0030836,"Any process that activates or increases the frequency, rate or extent of actin depolymerization.",positive regulation of actin filament depolymerization,biological_process
68328,GO:0030837,"Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.",negative regulation of actin filament polymerization,biological_process
68329,GO:0030838,"Any process that activates or increases the frequency, rate or extent of actin polymerization.",positive regulation of actin filament polymerization,biological_process
68330,GO:0030839,"Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.",regulation of intermediate filament polymerization,biological_process
68331,GO:0030840,"Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization.",negative regulation of intermediate filament polymerization,biological_process
68332,GO:0030841,"Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.",positive regulation of intermediate filament polymerization,biological_process
68333,GO:0030842,"Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.",regulation of intermediate filament depolymerization,biological_process
68334,GO:0030843,"Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization.",negative regulation of intermediate filament depolymerization,biological_process
68335,GO:0030844,"Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.",positive regulation of intermediate filament depolymerization,biological_process
68336,GO:0030845,A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).,phospholipase C-inhibiting G protein-coupled receptor signaling pathway,biological_process
68337,GO:0030846,An RNA polymerase II transcription termination process in which cleavage and polyadenylylation of the mRNA 3' end are coupled to transcription termination.,"termination of RNA polymerase II transcription, poly(A)-coupled",biological_process
68338,GO:0030847,The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.,"termination of RNA polymerase II transcription, exosome-dependent",biological_process
68339,GO:0030848,Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH4 + oxaloacetate.,threo-3-hydroxyaspartate ammonia-lyase activity,molecular_function
68340,GO:0030849,Any chromosome other than a sex chromosome.,autosome,cellular_component
68341,GO:0030850,"The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.",prostate gland development,biological_process
68342,GO:0030851,"The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.",granulocyte differentiation,biological_process
68343,GO:0030852,"Any process that modulates the frequency, rate or extent of granulocyte differentiation.",regulation of granulocyte differentiation,biological_process
68344,GO:0030853,"Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.",negative regulation of granulocyte differentiation,biological_process
68345,GO:0030854,"Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.",positive regulation of granulocyte differentiation,biological_process
68346,GO:0030855,"The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.",epithelial cell differentiation,biological_process
68347,GO:0030856,"Any process that modulates the frequency, rate or extent of epithelial cell differentiation.",regulation of epithelial cell differentiation,biological_process
68348,GO:0030857,"Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.",negative regulation of epithelial cell differentiation,biological_process
68349,GO:0030858,"Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.",positive regulation of epithelial cell differentiation,biological_process
68350,GO:0030859,The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.,polarized epithelial cell differentiation,biological_process
68351,GO:0030860,"Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.",regulation of polarized epithelial cell differentiation,biological_process
68352,GO:0030861,"Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation.",negative regulation of polarized epithelial cell differentiation,biological_process
68353,GO:0030862,Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.,positive regulation of polarized epithelial cell differentiation,biological_process
68354,GO:0030863,The portion of the cytoskeleton that lies just beneath the plasma membrane.,cortical cytoskeleton,cellular_component
68355,GO:0030864,"The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.",cortical actin cytoskeleton,cellular_component
68356,GO:0030865,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.",cortical cytoskeleton organization,biological_process
68357,GO:0030866,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.",cortical actin cytoskeleton organization,biological_process
68358,GO:0030867,The lipid bilayer surrounding the rough endoplasmic reticulum.,rough endoplasmic reticulum membrane,cellular_component
68359,GO:0030868,The lipid bilayer surrounding the smooth endoplasmic reticulum.,smooth endoplasmic reticulum membrane,cellular_component
68360,GO:0030869,"A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit.",RENT complex,cellular_component
68361,GO:0030870,"Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.",Mre11 complex,cellular_component
68362,GO:0030874,The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.,nucleolar chromatin,cellular_component
68363,GO:0030875,"Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining.",rDNA protrusion,cellular_component
68364,GO:0030876,"A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.",interleukin-20 receptor complex,cellular_component
68365,GO:0030877,"A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.",beta-catenin destruction complex,cellular_component
68366,GO:0030878,"The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.",thyroid gland development,biological_process
68367,GO:0030879,"The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.",mammary gland development,biological_process
68368,GO:0030880,Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.,RNA polymerase complex,cellular_component
68369,GO:0030881,Binding to beta-2-microglobulin.,beta-2-microglobulin binding,molecular_function
68370,GO:0030882,Binding to a lipid antigen.,lipid antigen binding,molecular_function
68371,GO:0030883,Binding to an endogenous cellular lipid antigen.,endogenous lipid antigen binding,molecular_function
68372,GO:0030884,Binding to an exogenous lipid antigen (examples include microbial lipids and glycolipids).,exogenous lipid antigen binding,molecular_function
68373,GO:0030885,Any process that modulates the frequency or rate of myeloid dendritic cell activation.,regulation of myeloid dendritic cell activation,biological_process
68374,GO:0030886,"Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.",negative regulation of myeloid dendritic cell activation,biological_process
68375,GO:0030887,"Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.",positive regulation of myeloid dendritic cell activation,biological_process
68376,GO:0030888,"Any process that modulates the frequency, rate or extent of B cell proliferation.",regulation of B cell proliferation,biological_process
68377,GO:0030889,"Any process that stops, prevents or reduces the rate or extent of B cell proliferation.",negative regulation of B cell proliferation,biological_process
68378,GO:0030890,Any process that activates or increases the rate or extent of B cell proliferation.,positive regulation of B cell proliferation,biological_process
68379,GO:0030891,"A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.",VCB complex,cellular_component
68380,GO:0030892,A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.,mitotic cohesin complex,cellular_component
68381,GO:0030893,A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.,meiotic cohesin complex,cellular_component
68382,GO:0030894,"A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.",replisome,cellular_component
68383,GO:0030895,"Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).",apolipoprotein B mRNA editing enzyme complex,cellular_component
68384,GO:0030896,Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.,checkpoint clamp complex,cellular_component
68385,GO:0030897,"A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.",HOPS complex,cellular_component
68386,GO:0030899,Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).,calcium-dependent ATPase activity,molecular_function
68387,GO:0030900,"The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions...",forebrain development,biological_process
68388,GO:0030901,"The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).",midbrain development,biological_process
68389,GO:0030902,"The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).",hindbrain development,biological_process
68390,GO:0030903,"The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.",notochord development,biological_process
68391,GO:0030904,"A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.",retromer complex,cellular_component
68392,GO:0030905,"The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.","retromer, tubulation complex",cellular_component
68393,GO:0030906,"The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.","retromer, cargo-selective complex",cellular_component
68394,GO:0030907,"A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.",MBF transcription complex,cellular_component
68395,GO:0030908,The post-translational removal of peptide sequences from within a protein sequence.,protein splicing,biological_process
68396,GO:0030909,"The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.",non-intein-mediated protein splicing,biological_process
68397,GO:0030910,The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.,olfactory placode formation,biological_process
68398,GO:0030911,"Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.",TPR domain binding,molecular_function
68399,GO:0030912,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.",response to deep water,biological_process
68400,GO:0030913,"Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.",paranodal junction assembly,biological_process
68401,GO:0030915,"A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.",Smc5-Smc6 complex,cellular_component
68402,GO:0030916,"The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.",otic vesicle formation,biological_process
68403,GO:0030917,"The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.",midbrain-hindbrain boundary development,biological_process
68404,GO:0030920,The acetylation of peptidyl-serine.,peptidyl-serine acetylation,biological_process
68405,GO:0030929,"Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.",ADPG pyrophosphorylase complex,cellular_component
68406,GO:0030930,A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species.,homotetrameric ADPG pyrophosphorylase complex,cellular_component
68407,GO:0030931,A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus.,heterotetrameric ADPG pyrophosphorylase complex,cellular_component
68408,GO:0030932,An ADPG pyrophosphorylase complex found in the amyloplast.,amyloplast ADPG pyrophosphorylase complex,cellular_component
68409,GO:0030933,An ADPG pyrophosphorylase complex found in the chloroplast.,chloroplast ADPG pyrophosphorylase complex,cellular_component
68410,GO:0030936,Any collagen trimer that passes through a lipid bilayer membrane.,transmembrane collagen trimer,cellular_component
68411,GO:0030937,A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin.,collagen type XVII trimer,cellular_component
68412,GO:0030938,A collagen homotrimer of alpha1(XVIII) chains.,collagen type XVIII trimer,cellular_component
68413,GO:0030941,"Binding to a chloroplast targeting sequence, a short stretch of amino acids found in a protein that acts as a signal to localize the protein to the chloroplast.",chloroplast targeting sequence receptor activity,molecular_function
68414,GO:0030942,"Binding to an endoplasmic reticulum signal peptide, a short stretch of amino acids found in a protein that acts as a signal to localize the protein to the endoplasmic reticulum.",endoplasmic reticulum signal sequence receptor activity,molecular_function
68415,GO:0030946,Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.,"protein tyrosine phosphatase activity, metal-dependent",molecular_function
68416,GO:0030947,"Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.",regulation of vascular endothelial growth factor receptor signaling pathway,biological_process
68417,GO:0030948,"Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.",negative regulation of vascular endothelial growth factor receptor signaling pathway,biological_process
68418,GO:0030949,"Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.",positive regulation of vascular endothelial growth factor receptor signaling pathway,biological_process
68419,GO:0030950,"Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.",establishment or maintenance of actin cytoskeleton polarity,biological_process
68420,GO:0030951,"Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.",establishment or maintenance of microtubule cytoskeleton polarity,biological_process
68421,GO:0030952,"Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.",establishment or maintenance of cytoskeleton polarity,biological_process
68422,GO:0030953,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.",astral microtubule organization,biological_process
68423,GO:0030954,"The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.",astral microtubule nucleation,biological_process
68424,GO:0030955,Binding to a potassium ion (K+).,potassium ion binding,molecular_function
68425,GO:0030956,"A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.",glutamyl-tRNA(Gln) amidotransferase complex,cellular_component
68426,GO:0030957,"Binding to Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus.",Tat protein binding,molecular_function
68427,GO:0030958,"A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing.",RITS complex,cellular_component
68428,GO:0030961,The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.,peptidyl-arginine hydroxylation,biological_process
68429,GO:0030964,An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.,NADH dehydrogenase complex,cellular_component
68430,GO:0030965,"The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.","plasma membrane electron transport, NADH to quinone",biological_process
68431,GO:0030968,The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.,endoplasmic reticulum unfolded protein response,biological_process
68432,GO:0030970,The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.,"retrograde protein transport, ER to cytosol",biological_process
68433,GO:0030971,Binding to a receptor that possesses protein tyrosine kinase activity.,receptor tyrosine kinase binding,molecular_function
68434,GO:0030973,Binding to a molybdate ion (MoO4 2-).,molybdate ion binding,molecular_function
68435,GO:0030974,The process in which thiamine pyrophosphate is transported across a membrane.,thiamine pyrophosphate transmembrane transport,biological_process
68436,GO:0030975,"Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine binding,molecular_function
68437,GO:0030976,"Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.",thiamine pyrophosphate binding,molecular_function
68438,GO:0030977,Binding to taurine.,taurine binding,molecular_function
68439,GO:0030978,"The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.",alpha-glucan metabolic process,biological_process
68440,GO:0030979,"The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.",alpha-glucan biosynthetic process,biological_process
68441,GO:0030980,The chemical reactions and pathways resulting in the breakdown of alpha-glucans.,alpha-glucan catabolic process,biological_process
68442,GO:0030981,The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.,cortical microtubule cytoskeleton,cellular_component
68443,GO:0030982,A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.,adventurous gliding motility,biological_process
68444,GO:0030983,Binding to a double-stranded DNA region containing one or more mismatches.,mismatched DNA binding,molecular_function
68445,GO:0030984,"Binding to a kininogen, a kinin precursor.",kininogen binding,molecular_function
68446,GO:0030985,Binding to a kininogen of high molecular mass.,high molecular weight kininogen binding,molecular_function
68447,GO:0030986,Binding to a kininogen of low molecular mass.,low molecular weight kininogen binding,molecular_function
68448,GO:0030987,Binding to a high molecular weight kininogen receptor.,high molecular weight kininogen receptor binding,molecular_function
68449,GO:0030988,"A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.",high molecular weight kininogen receptor complex,cellular_component
68450,GO:0030989,"Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.",dynein-driven meiotic oscillatory nuclear movement,biological_process
68451,GO:0030990,A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.,intraciliary transport particle,cellular_component
68452,GO:0030991,The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.,intraciliary transport particle A,cellular_component
68453,GO:0030992,The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.,intraciliary transport particle B,cellular_component
68454,GO:0030993,"A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.",axonemal heterotrimeric kinesin-II complex,cellular_component
68455,GO:0030994,Dissolution of the primary septum during cell separation.,primary cell septum disassembly,biological_process
68456,GO:0030995,The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.,cell septum edging catabolic process,biological_process
68457,GO:0030997,Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.,regulation of centriole-centriole cohesion,biological_process
68458,GO:0030998,"A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex.",linear element,cellular_component
68459,GO:0030999,The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex.,linear element assembly,biological_process
68460,GO:0031000,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.",response to caffeine,biological_process
68461,GO:0031001,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.",response to brefeldin A,biological_process
68462,GO:0031002,"A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions.",actin rod,cellular_component
68463,GO:0031003,"A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.",actin tubule,cellular_component
68464,GO:0031004,"Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.",potassium ion-transporting ATPase complex,cellular_component
68465,GO:0031005,"Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.",filamin binding,molecular_function
68466,GO:0031009,An ADPG pyrophosphorylase complex found in a plastid.,plastid ADPG pyrophosphorylase complex,cellular_component
68467,GO:0031010,"Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.",ISWI-type complex,cellular_component
68468,GO:0031011,A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.,Ino80 complex,cellular_component
68469,GO:0031012,"A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.",extracellular matrix,cellular_component
68470,GO:0031013,"Binding to troponin I, the inhibitory subunit of the troponin complex.",troponin I binding,molecular_function
68471,GO:0031014,"Binding to troponin T, the tropomyosin-binding subunit of the troponin complex.",troponin T binding,molecular_function
68472,GO:0031016,"The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.",pancreas development,biological_process
68473,GO:0031017,"The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.",exocrine pancreas development,biological_process
68474,GO:0031018,"The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.",endocrine pancreas development,biological_process
68475,GO:0031019,"An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.",mitochondrial mRNA editing complex,cellular_component
68476,GO:0031020,An mRNA editing complex found in a plastid.,plastid mRNA editing complex,cellular_component
68477,GO:0031021,"A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.",interphase microtubule organizing center,cellular_component
68478,GO:0031022,"The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.",nuclear migration along microfilament,biological_process
68479,GO:0031023,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.",microtubule organizing center organization,biological_process
68480,GO:0031024,"The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.",interphase microtubule organizing center assembly,biological_process
68481,GO:0031025,The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.,equatorial microtubule organizing center disassembly,biological_process
68482,GO:0031026,A complex that possesses glutamate synthase activity.,glutamate synthase complex,cellular_component
68483,GO:0031027,A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.,glutamate synthase complex (NADH),cellular_component
68484,GO:0031028,"The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.",septation initiation signaling,biological_process
68485,GO:0031029,"Any process that modulates the frequency, rate or extent of septation initiation signaling.",regulation of septation initiation signaling,biological_process
68486,GO:0031030,"Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.",negative regulation of septation initiation signaling,biological_process
68487,GO:0031031,"Any process that activates or increases the frequency, rate or extent of septation initiation signaling.",positive regulation of septation initiation signaling,biological_process
68488,GO:0031032,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.",actomyosin structure organization,biological_process
68489,GO:0031033,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.",myosin filament organization,biological_process
68490,GO:0031034,"The aggregation, arrangement and bonding together of a filament composed of myosin molecules.",myosin filament assembly,biological_process
68491,GO:0031035,The disassembly of a filament composed of myosin molecules.,myosin filament disassembly,biological_process
68492,GO:0031036,The formation of a bipolar filament composed of myosin II molecules.,myosin II filament assembly,biological_process
68493,GO:0031037,The disassembly of a bipolar filament composed of myosin II molecules.,myosin II filament disassembly,biological_process
68494,GO:0031038,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.",myosin II filament organization,biological_process
68495,GO:0031039,A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.,macronucleus,cellular_component
68496,GO:0031040,"A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.",micronucleus,cellular_component
68497,GO:0031045,Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.,dense core granule,cellular_component
68498,GO:0031047,"A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, l...",regulatory ncRNA-mediated gene silencing,biological_process
68499,GO:0031048,A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginning of trancription.,regulatory ncRNA-mediated heterochromatin formation,biological_process
68500,GO:0031049,"A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.",programmed DNA elimination,biological_process
68501,GO:0031052,Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.,programmed DNA elimination by chromosome breakage,biological_process
68502,GO:0031053,A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.,primary miRNA processing,biological_process
68503,GO:0031054,A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.,pre-miRNA processing,biological_process
68504,GO:0031069,The process in which the anatomical structures of the hair follicle are generated and organized.,hair follicle morphogenesis,biological_process
68505,GO:0031070,"The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.",intronic snoRNA processing,biological_process
68506,GO:0031071,Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.,cysteine desulfurase activity,molecular_function
68507,GO:0031072,"Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.",heat shock protein binding,molecular_function
68508,GO:0031073,Catalysis of the reaction: cholesterol + H+ NADPH + O2 = 26-hydroxycholesterol + H2O + NADP+.,cholesterol 26-hydroxylase activity,molecular_function
68509,GO:0031074,Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.,nucleocytoplasmic transport complex,cellular_component
68510,GO:0031076,"The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.",embryonic camera-type eye development,biological_process
68511,GO:0031077,"The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.",post-embryonic camera-type eye development,biological_process
68512,GO:0031078,Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.,"histone H3K14 deacetylase activity, hydrolytic mechanism",molecular_function
68513,GO:0031080,"A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Compone...",nuclear pore outer ring,cellular_component
68514,GO:0031082,"Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.",BLOC complex,cellular_component
68515,GO:0031083,"A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.",BLOC-1 complex,cellular_component
68516,GO:0031084,"A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.",BLOC-2 complex,cellular_component
68517,GO:0031085,"A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.",BLOC-3 complex,cellular_component
68518,GO:0031086,"A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.","nuclear-transcribed mRNA catabolic process, deadenylation-independent decay",biological_process
68519,GO:0031087,Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.,deadenylation-independent decapping of nuclear-transcribed mRNA,biological_process
68520,GO:0031088,The lipid bilayer surrounding the platelet dense granule.,platelet dense granule membrane,cellular_component
68521,GO:0031089,The volume enclosed by the membrane of the platelet dense granule.,platelet dense granule lumen,cellular_component
68522,GO:0031090,A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.,organelle membrane,cellular_component
68523,GO:0031091,"A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).",platelet alpha granule,cellular_component
68524,GO:0031092,The lipid bilayer surrounding the platelet alpha granule.,platelet alpha granule membrane,cellular_component
68525,GO:0031093,The volume enclosed by the membrane of the platelet alpha granule.,platelet alpha granule lumen,cellular_component
68526,GO:0031094,"A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.",platelet dense tubular network,cellular_component
68527,GO:0031095,The lipid bilayer surrounding the platelet dense tubular network.,platelet dense tubular network membrane,cellular_component
68528,GO:0031096,The volume enclosed by the membranes of the platelet dense tubular network.,platelet dense tubular network lumen,cellular_component
68529,GO:0031097,A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.,medial cortex,cellular_component
68530,GO:0031098,The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.,stress-activated protein kinase signaling cascade,biological_process
68531,GO:0031099,"The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).",regeneration,biological_process
68532,GO:0031100,The regrowth of a lost or destroyed animal organ.,animal organ regeneration,biological_process
68533,GO:0031101,The regrowth of fin tissue following its loss or destruction.,fin regeneration,biological_process
68534,GO:0031102,The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.,neuron projection regeneration,biological_process
68535,GO:0031103,The regrowth of axons following their loss or damage.,axon regeneration,biological_process
68536,GO:0031104,The regrowth of dendrites in response to their loss or damage.,dendrite regeneration,biological_process
68537,GO:0031105,"A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.",septin complex,cellular_component
68538,GO:0031106,"Control of the formation, spatial distribution, and breakdown of the septin ring.",septin ring organization,biological_process
68539,GO:0031107,The controlled breakdown of a septin ring.,septin ring disassembly,biological_process
68540,GO:0031108,The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].,holo-[acyl-carrier-protein] biosynthetic process,biological_process
68541,GO:0031109,Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.,microtubule polymerization or depolymerization,biological_process
68542,GO:0031110,"Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.",regulation of microtubule polymerization or depolymerization,biological_process
68543,GO:0031111,"Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.",negative regulation of microtubule polymerization or depolymerization,biological_process
68544,GO:0031112,"Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.",positive regulation of microtubule polymerization or depolymerization,biological_process
68545,GO:0031113,"Any process that modulates the frequency, rate or extent of microtubule polymerization.",regulation of microtubule polymerization,biological_process
68546,GO:0031114,"Any process that modulates the frequency, rate or extent of microtubule depolymerization.",regulation of microtubule depolymerization,biological_process
68547,GO:0031115,"Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.",negative regulation of microtubule polymerization,biological_process
68548,GO:0031116,"Any process that activates or increases the frequency, rate or extent of microtubule polymerization.",positive regulation of microtubule polymerization,biological_process
68549,GO:0031117,"Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.",positive regulation of microtubule depolymerization,biological_process
68550,GO:0031118,The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.,rRNA pseudouridine synthesis,biological_process
68551,GO:0031119,The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.,tRNA pseudouridine synthesis,biological_process
68552,GO:0031120,The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.,snRNA pseudouridine synthesis,biological_process
68553,GO:0031121,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.",equatorial microtubule organization,biological_process
68554,GO:0031122,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.",cytoplasmic microtubule organization,biological_process
68555,GO:0031123,Any process involved in forming the mature 3' end of an RNA molecule.,RNA 3'-end processing,biological_process
68556,GO:0031124,Any process involved in forming the mature 3' end of an mRNA molecule.,mRNA 3'-end processing,biological_process
68557,GO:0031125,Any process involved in forming the mature 3' end of an rRNA molecule.,rRNA 3'-end processing,biological_process
68558,GO:0031126,"Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea.",sno(s)RNA 3'-end processing,biological_process
68559,GO:0031127,Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.,"alpha-(1,2)-fucosyltransferase activity",molecular_function
68560,GO:0031128,A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).,developmental induction,biological_process
68561,GO:0031129,Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.,inductive cell-cell signaling,biological_process
68562,GO:0031132,Catalysis of the reaction: L-serine + NADP+ = L-alpha-formylglycine + 2 H+ + NADPH.,serine 3-dehydrogenase activity,molecular_function
68563,GO:0031133,"Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.",regulation of axon diameter,biological_process
68564,GO:0031134,The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.,sister chromatid biorientation,biological_process
68565,GO:0031137,Any process that modulates the rate or frequency of conjugation with cellular fusion.,regulation of conjugation with cellular fusion,biological_process
68566,GO:0031138,Any process that decreases the rate or frequency of conjugation with cellular fusion.,negative regulation of conjugation with cellular fusion,biological_process
68567,GO:0031139,Any process that increases the rate or frequency of conjugation with cellular fusion.,positive regulation of conjugation with cellular fusion,biological_process
68568,GO:0031140,The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.,induction of conjugation upon nutrient starvation,biological_process
68569,GO:0031141,The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.,induction of conjugation upon carbon starvation,biological_process
68570,GO:0031142,The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.,induction of conjugation upon nitrogen starvation,biological_process
68571,GO:0031143,"A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.",pseudopodium,cellular_component
68572,GO:0031144,"Any process in which the proteasome is transported to, or maintained in, a specific location.",proteasome localization,biological_process
68573,GO:0031145,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.",anaphase-promoting complex-dependent catabolic process,biological_process
68574,GO:0031146,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.",SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,biological_process
68575,GO:0031147,"The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.","1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process",biological_process
68576,GO:0031148,"The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.",DIF-1 biosynthetic process,biological_process
68577,GO:0031149,"The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.",sorocarp stalk cell differentiation,biological_process
68578,GO:0031150,"The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.",sorocarp stalk development,biological_process
68579,GO:0031151,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group to the lysine residue at position 79 of the histone H3 protein.,histone H3K79 methyltransferase activity,molecular_function
68580,GO:0031152,"The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.",aggregation involved in sorocarp development,biological_process
68581,GO:0031153,"The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.",slug development involved in sorocarp development,biological_process
68582,GO:0031154,"The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.",culmination involved in sorocarp development,biological_process
68583,GO:0031155,"Any process that modulates the frequency, rate or extent of reproductive fruiting body development.",regulation of reproductive fruiting body development,biological_process
68584,GO:0031156,"Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.",regulation of sorocarp development,biological_process
68585,GO:0031157,Any process that modulates the size of the aggregate formed during sorocarp formation.,regulation of aggregate size involved in sorocarp development,biological_process
68586,GO:0031158,Any process that decreases the size of the aggregate formed during sorocarp formation.,negative regulation of aggregate size involved in sorocarp development,biological_process
68587,GO:0031159,Any process that increases the size of the aggregate formed during sorocarp formation.,positive regulation of aggregate size involved in sorocarp development,biological_process
68588,GO:0031160,The specialized envelope lying outside the cell membrane of a spore.,spore wall,cellular_component
68589,GO:0031161,"The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.",phosphatidylinositol catabolic process,biological_process
68590,GO:0031163,The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.,metallo-sulfur cluster assembly,biological_process
68591,GO:0031164,The lipid bilayer surrounding the contractile vacuole.,contractile vacuolar membrane,cellular_component
68592,GO:0031167,The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.,rRNA methylation,biological_process
68593,GO:0031169,The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.,ferrichrome biosynthetic process,biological_process
68594,GO:0031171,"The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.",ferricrocin biosynthetic process,biological_process
68595,GO:0031172,Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.,ornithine N5-monooxygenase activity,molecular_function
68596,GO:0031173,The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.,otolith mineralization completed early in development,biological_process
68597,GO:0031174,"The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.",lifelong otolith mineralization,biological_process
68598,GO:0031175,"The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).",neuron projection development,biological_process
68599,GO:0031176,Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.,"endo-1,4-beta-xylanase activity",molecular_function
68600,GO:0031177,"Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).",phosphopantetheine binding,molecular_function
68601,GO:0031179,"The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.",peptide modification,biological_process
68602,GO:0031201,"A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.",SNARE complex,cellular_component
68603,GO:0031203,The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex.,"post-translational protein targeting to membrane, docking",biological_process
68604,GO:0031204,The process in which a protein translocates through the ER membrane posttranslationally.,"post-translational protein targeting to membrane, translocation",biological_process
68605,GO:0031205,"An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex.",endoplasmic reticulum Sec complex,cellular_component
68606,GO:0031207,"A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.",Sec62/Sec63 complex,cellular_component
68607,GO:0031208,"Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.",POZ domain binding,molecular_function
68608,GO:0031209,"A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.",SCAR complex,cellular_component
68609,GO:0031210,"Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline.",phosphatidylcholine binding,molecular_function
68610,GO:0031211,"A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue.",endoplasmic reticulum palmitoyltransferase complex,cellular_component
68611,GO:0031213,"An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).",RSF complex,cellular_component
68612,GO:0031214,"Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.",biomineral tissue development,biological_process
68613,GO:0031215,"The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell.",shell calcification,biological_process
68614,GO:0031216,Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).,neopullulanase activity,molecular_function
68615,GO:0031217,"Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.","glucan 1,4-beta-glucosidase activity",molecular_function
68616,GO:0031218,Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.,"arabinogalactan endo-1,4-beta-galactosidase activity",molecular_function
68617,GO:0031219,"Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.",levanase activity,molecular_function
68618,GO:0031220,Catalysis of the reaction: alpha-maltotetraose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltotriose.,maltodextrin phosphorylase activity,molecular_function
68619,GO:0031221,"The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.",arabinan metabolic process,biological_process
68620,GO:0031222,"The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.",arabinan catabolic process,biological_process
68621,GO:0031223,The behavior of an organism in response to a sound.,auditory behavior,biological_process
68622,GO:0031232,"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.",extrinsic component of external side of plasma membrane,cellular_component
68623,GO:0031234,"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.",extrinsic component of cytoplasmic side of plasma membrane,cellular_component
68624,GO:0031236,"The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region.",extrinsic component of periplasmic side of plasma membrane,cellular_component
68625,GO:0031240,"The leaflet of the outer membrane that is opposite to the side that faces the periplasm of the cell, including any protein embedded in, attached to, or peripherally associated with it.",external side of cell outer membrane,cellular_component
68626,GO:0031241,"The leaflet of a outer cell membrane that faces the periplasm, including any protein embedded in, attached to, or peripherally associated with it.",periplasmic side of cell outer membrane,cellular_component
68627,GO:0031242,"The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.",extrinsic component of external side of cell outer membrane,cellular_component
68628,GO:0031244,"The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of cell outer membrane,cellular_component
68629,GO:0031245,"The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region.",extrinsic component of periplasmic side of cell outer membrane,cellular_component
68630,GO:0031247,"The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.",actin rod assembly,biological_process
68631,GO:0031248,A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.,protein acetyltransferase complex,cellular_component
68632,GO:0031250,"An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.",anaerobic ribonucleoside-triphosphate reductase complex,cellular_component
68633,GO:0031251,"A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.",PAN complex,cellular_component
68634,GO:0031252,The area of a motile cell closest to the direction of movement.,cell leading edge,cellular_component
68635,GO:0031253,The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.,cell projection membrane,cellular_component
68636,GO:0031254,The area of a motile cell opposite to the direction of movement.,cell trailing edge,cellular_component
68637,GO:0031255,The area of a motile cell perpendicular to the direction of movement.,lateral part of motile cell,cellular_component
68638,GO:0031256,The portion of the plasma membrane surrounding the leading edge of a motile cell.,leading edge membrane,cellular_component
68639,GO:0031257,The portion of the plasma membrane surrounding the trailing edge of a motile cell.,cell trailing edge membrane,cellular_component
68640,GO:0031258,The portion of the plasma membrane surrounding a lamellipodium.,lamellipodium membrane,cellular_component
68641,GO:0031259,The portion of the plasma membrane surrounding a uropod.,uropod membrane,cellular_component
68642,GO:0031260,The portion of the plasma membrane surrounding a pseudopodium.,pseudopodium membrane,cellular_component
68643,GO:0031261,"A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.",DNA replication preinitiation complex,cellular_component
68644,GO:0031262,An essential outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis.,Ndc80 complex,cellular_component
68645,GO:0031264,"A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.",death-inducing signaling complex,cellular_component
68646,GO:0031265,"A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.",CD95 death-inducing signaling complex,cellular_component
68647,GO:0031266,A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.,TRAIL death-inducing signaling complex,cellular_component
68648,GO:0031267,Binding to a small monomeric GTPase.,small GTPase binding,molecular_function
68649,GO:0031268,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.",pseudopodium organization,biological_process
68650,GO:0031269,The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.,pseudopodium assembly,biological_process
68651,GO:0031270,The myosin-based contraction and retraction of a pseudopodium.,pseudopodium retraction,biological_process
68652,GO:0031271,The extension of a pseudopodium from the lateral area of a cell.,lateral pseudopodium assembly,biological_process
68653,GO:0031272,"Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.",regulation of pseudopodium assembly,biological_process
68654,GO:0031273,"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.",negative regulation of pseudopodium assembly,biological_process
68655,GO:0031274,"Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.",positive regulation of pseudopodium assembly,biological_process
68656,GO:0031278,"Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.","alpha-1,2-galactosyltransferase activity",molecular_function
68657,GO:0031281,Any process that activates or increases the activity of a cyclase.,positive regulation of cyclase activity,biological_process
68658,GO:0031283,"Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.",negative regulation of guanylate cyclase activity,biological_process
68659,GO:0031284,"Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.",positive regulation of guanylate cyclase activity,biological_process
68660,GO:0031285,"Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.",regulation of sorocarp stalk cell differentiation,biological_process
68661,GO:0031286,"Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.",negative regulation of sorocarp stalk cell differentiation,biological_process
68662,GO:0031287,"Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.",positive regulation of sorocarp stalk cell differentiation,biological_process
68663,GO:0031288,The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.,sorocarp morphogenesis,biological_process
68664,GO:0031290,The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.,retinal ganglion cell axon guidance,biological_process
68665,GO:0031291,An intracellular signaling cassette in which a small monomeric GTPase of the Ran subfamily relays a signal.,Ran protein signal transduction,biological_process
68666,GO:0031293,The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.,membrane protein intracellular domain proteolysis,biological_process
68667,GO:0031294,"The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.",lymphocyte costimulation,biological_process
68668,GO:0031295,"The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.",T cell costimulation,biological_process
68669,GO:0031296,"The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.",B cell costimulation,biological_process
68670,GO:0031297,"The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.",replication fork processing,biological_process
68671,GO:0031298,A heterotrimeric replication-pausing complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. Required for maximal fork speed both in vivo and in vitro.,replication fork protection complex,cellular_component
68672,GO:0031299,Catalysis of the reaction: taurine + pyruvate = sulfoacetaldehyde + L-alanine.,taurine:pyruvate transaminase activity,molecular_function
68673,GO:0031312,"The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of organelle membrane,cellular_component
68674,GO:0031313,"The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of endosome membrane,cellular_component
68675,GO:0031314,"The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of mitochondrial inner membrane,cellular_component
68676,GO:0031315,"The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of mitochondrial outer membrane,cellular_component
68677,GO:0031316,"The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of nuclear outer membrane,cellular_component
68678,GO:0031317,"A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients.",tripartite ATP-independent periplasmic transporter complex,cellular_component
68679,GO:0031318,The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.,detection of folic acid,biological_process
68680,GO:0031319,"The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.",detection of cAMP,biological_process
68681,GO:0031320,Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.,hexitol dehydrogenase activity,molecular_function
68682,GO:0031321,"During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.",ascospore-type prospore assembly,biological_process
68683,GO:0031322,A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).,ascospore-type prospore-specific spindle pole body remodeling,biological_process
68684,GO:0031332,Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.,RNAi effector complex,cellular_component
68685,GO:0031333,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.",negative regulation of protein-containing complex assembly,biological_process
68686,GO:0031334,"Any process that activates or increases the frequency, rate or extent of protein complex assembly.",positive regulation of protein-containing complex assembly,biological_process
68687,GO:0031338,"Any process that modulates the frequency, rate or extent of vesicle fusion.",regulation of vesicle fusion,biological_process
68688,GO:0031339,"Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.",negative regulation of vesicle fusion,biological_process
68689,GO:0031340,"Any process that activates or increases the frequency, rate or extent of vesicle fusion.",positive regulation of vesicle fusion,biological_process
68690,GO:0031341,"Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.",regulation of cell killing,biological_process
68691,GO:0031342,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.",negative regulation of cell killing,biological_process
68692,GO:0031343,"Any process that activates or increases the frequency, rate or extent of cell killing.",positive regulation of cell killing,biological_process
68693,GO:0031344,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.",regulation of cell projection organization,biological_process
68694,GO:0031345,"Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.",negative regulation of cell projection organization,biological_process
68695,GO:0031346,"Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.",positive regulation of cell projection organization,biological_process
68696,GO:0031347,"Any process that modulates the frequency, rate or extent of a defense response.",regulation of defense response,biological_process
68697,GO:0031348,"Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.",negative regulation of defense response,biological_process
68698,GO:0031349,"Any process that activates or increases the frequency, rate or extent of a defense response.",positive regulation of defense response,biological_process
68699,GO:0031363,The removal of an amino group from the N-terminal amino acid residue of a protein.,N-terminal protein amino acid deamination,biological_process
68700,GO:0031364,The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.,"N-terminal protein amino acid deamination, from side chain",biological_process
68701,GO:0031365,The alteration of the N-terminal amino acid residue in a protein.,N-terminal protein amino acid modification,biological_process
68702,GO:0031369,"Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.",translation initiation factor binding,molecular_function
68703,GO:0031370,"Binding to eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.",eukaryotic initiation factor 4G binding,molecular_function
68704,GO:0031371,Any complex that possesses ubiquitin conjugating enzyme activity.,ubiquitin conjugating enzyme complex,cellular_component
68705,GO:0031372,"A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains. In Saccharomyces cerevisiae, the complex comprises Ubc13p and Mms2p; in human it comprises UBE2N and UBE2V1/UBE2V2; and in plants UBC35/UBC36 and UEV1A/UEV1B/UEV1C/UEV1D-4.",UBC13-MMS2 complex,cellular_component
68706,GO:0031379,A protein complex that possesses RNA-directed RNA polymerase activity.,RNA-directed RNA polymerase complex,cellular_component
68707,GO:0031380,"A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.",nuclear RNA-directed RNA polymerase complex,cellular_component
68708,GO:0031381,A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus.,viral RNA-directed RNA polymerase complex,cellular_component
68709,GO:0031382,"The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.",mating projection formation,biological_process
68710,GO:0031383,"Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi.",regulation of mating projection assembly,biological_process
68711,GO:0031384,"Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.",regulation of initiation of mating projection growth,biological_process
68712,GO:0031385,"Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.",regulation of termination of mating projection growth,biological_process
68713,GO:0031386,"A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.",protein tag activity,molecular_function
68714,GO:0031387,A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).,MPF complex,cellular_component
68715,GO:0031389,"A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.",Rad17 RFC-like complex,cellular_component
68716,GO:0031390,"A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p.",Ctf18 RFC-like complex,cellular_component
68717,GO:0031391,"A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.",Elg1 RFC-like complex,cellular_component
68718,GO:0031392,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",regulation of prostaglandin biosynthetic process,biological_process
68719,GO:0031393,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",negative regulation of prostaglandin biosynthetic process,biological_process
68720,GO:0031394,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",positive regulation of prostaglandin biosynthetic process,biological_process
68721,GO:0031395,A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits.,bursicon neuropeptide hormone complex,cellular_component
68722,GO:0031396,"Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.",regulation of protein ubiquitination,biological_process
68723,GO:0031397,"Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.",negative regulation of protein ubiquitination,biological_process
68724,GO:0031398,"Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.",positive regulation of protein ubiquitination,biological_process
68725,GO:0031399,"Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.",regulation of protein modification process,biological_process
68726,GO:0031400,"Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.",negative regulation of protein modification process,biological_process
68727,GO:0031401,"Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.",positive regulation of protein modification process,biological_process
68728,GO:0031402,Binding to a sodium ion (Na+).,sodium ion binding,molecular_function
68729,GO:0031403,Binding to a lithium ion (Li+).,lithium ion binding,molecular_function
68730,GO:0031404,Binding to a chloride ion (Cl-).,chloride ion binding,molecular_function
68731,GO:0031405,"Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.",lipoic acid binding,molecular_function
68732,GO:0031406,"Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).",carboxylic acid binding,molecular_function
68733,GO:0031407,"The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.",oxylipin metabolic process,biological_process
68734,GO:0031408,"The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.",oxylipin biosynthetic process,biological_process
68735,GO:0031409,"Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.",pigment binding,molecular_function
68736,GO:0031410,A vesicle found in the cytoplasm of a cell.,cytoplasmic vesicle,cellular_component
68737,GO:0031411,"An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.",gas vesicle,cellular_component
68738,GO:0031412,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps.",gas vesicle organization,biological_process
68739,GO:0031413,"Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases.",regulation of buoyancy,biological_process
68740,GO:0031414,A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.,N-terminal protein acetyltransferase complex,cellular_component
68741,GO:0031415,"A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.",NatA complex,cellular_component
68742,GO:0031416,"A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p.",NatB complex,cellular_component
68743,GO:0031417,"A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.",NatC complex,cellular_component
68744,GO:0031418,"Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.",L-ascorbic acid binding,molecular_function
68745,GO:0031419,"Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.",cobalamin binding,molecular_function
68746,GO:0031420,"Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.",alkali metal ion binding,molecular_function
68747,GO:0031421,"A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.",invertasome,cellular_component
68748,GO:0031422,A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human.,RecQ family helicase-topoisomerase III complex,cellular_component
68749,GO:0031423,"Binding to a hexon, the major protein component of the icosahedral capsid of an adenovirus.",hexon binding,molecular_function
68750,GO:0031424,"The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.",keratinization,biological_process
68751,GO:0031425,The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.,chloroplast RNA processing,biological_process
68752,GO:0031426,The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.,polycistronic mRNA processing,biological_process
68753,GO:0031427,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.",response to methotrexate,biological_process
68754,GO:0031428,"A ribonucleoprotein complex containing a box C/D type RNA that is capable of ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.",box C/D methylation guide snoRNP complex,cellular_component
68755,GO:0031429,A box H/ACA small nucleolar ribonucleoprotein complex located in the nucleolus that catalyzes pseudouridylation of ribosomal RNA residues. The complex is composed of four different core proteins that assemble onto a H/ACA guide RNA scaffold that identifies specific uridines in rRNA for modification during ribosome synthesis.,box H/ACA snoRNP complex,cellular_component
68756,GO:0031430,The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.,M band,cellular_component
68757,GO:0031431,"A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.",Dbf4-dependent protein kinase complex,cellular_component
68758,GO:0031432,"Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.",titin binding,molecular_function
68759,GO:0031433,"Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.",telethonin binding,molecular_function
68760,GO:0031434,"Binding to a mitogen-activated protein kinase kinase, a protein that can phosphorylate a MAP kinase.",mitogen-activated protein kinase kinase binding,molecular_function
68761,GO:0031435,"Binding to a mitogen-activated protein kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase.",mitogen-activated protein kinase kinase kinase binding,molecular_function
68762,GO:0031436,"A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.",BRCA1-BARD1 complex,cellular_component
68763,GO:0031440,"Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.",regulation of mRNA 3'-end processing,biological_process
68764,GO:0031441,"Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.",negative regulation of mRNA 3'-end processing,biological_process
68765,GO:0031442,"Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.",positive regulation of mRNA 3'-end processing,biological_process
68766,GO:0031443,"A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.",fast-twitch skeletal muscle fiber contraction,biological_process
68767,GO:0031444,"A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.",slow-twitch skeletal muscle fiber contraction,biological_process
68768,GO:0031445,"Any process that modulates the frequency, rate, extent or location of heterochromatin formation.",regulation of heterochromatin formation,biological_process
68769,GO:0031446,"Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.",regulation of fast-twitch skeletal muscle fiber contraction,biological_process
68770,GO:0031447,"Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.",negative regulation of fast-twitch skeletal muscle fiber contraction,biological_process
68771,GO:0031448,"Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.",positive regulation of fast-twitch skeletal muscle fiber contraction,biological_process
68772,GO:0031449,"Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.",regulation of slow-twitch skeletal muscle fiber contraction,biological_process
68773,GO:0031450,"Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.",negative regulation of slow-twitch skeletal muscle fiber contraction,biological_process
68774,GO:0031451,"Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.",positive regulation of slow-twitch skeletal muscle fiber contraction,biological_process
68775,GO:0031452,"Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.",negative regulation of heterochromatin formation,biological_process
68776,GO:0031453,"Any process that activates or increases the frequency, rate or extent of heterochromatin formation.",positive regulation of heterochromatin formation,biological_process
68777,GO:0031456,"The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.",glycine betaine biosynthetic process,biological_process
68778,GO:0031457,"The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.",glycine betaine catabolic process,biological_process
68779,GO:0031458,Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).,ABC-type betaine transporter activity,molecular_function
68780,GO:0031459,Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).,ABC-type glycine betaine transporter activity,molecular_function
68781,GO:0031460,"The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycine betaine transport,biological_process
68782,GO:0031461,Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.,cullin-RING ubiquitin ligase complex,cellular_component
68783,GO:0031462,A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.,Cul2-RING ubiquitin ligase complex,cellular_component
68784,GO:0031463,A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.,Cul3-RING ubiquitin ligase complex,cellular_component
68785,GO:0031464,A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.,Cul4A-RING E3 ubiquitin ligase complex,cellular_component
68786,GO:0031465,A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.,Cul4B-RING E3 ubiquitin ligase complex,cellular_component
68787,GO:0031466,A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.,Cul5-RING ubiquitin ligase complex,cellular_component
68788,GO:0031467,A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.,Cul7-RING ubiquitin ligase complex,cellular_component
68789,GO:0031468,The reformation of the nuclear membranes following their breakdown in the context of a normal process.,nuclear membrane reassembly,biological_process
68790,GO:0031469,An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.,bacterial microcompartment,cellular_component
68791,GO:0031470,An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO2. It augments the concentration of CO2 in the vicinity of RuBisCO to increase the efficiency of CO2 fixation under atmospheric conditions.,carboxysome,cellular_component
68792,GO:0031471,An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.,ethanolamine degradation polyhedral organelle,cellular_component
68793,GO:0031472,"An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.",propanediol degradation polyhedral organelle,cellular_component
68794,GO:0031473,Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.,myosin III binding,molecular_function
68795,GO:0031474,"A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.",myosin IV complex,cellular_component
68796,GO:0031475,A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.,myosin V complex,cellular_component
68797,GO:0031476,A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.,myosin VI complex,cellular_component
68798,GO:0031477,"A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.",myosin VII complex,cellular_component
68799,GO:0031478,"A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.",myosin VIII complex,cellular_component
68800,GO:0031479,"A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.",myosin IX complex,cellular_component
68801,GO:0031480,A myosin complex containing one or more class X myosin heavy chains and associated light chains.,myosin X complex,cellular_component
68802,GO:0031481,A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.,myosin XI complex,cellular_component
68803,GO:0031482,A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.,myosin XII complex,cellular_component
68804,GO:0031483,A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.,myosin XIII complex,cellular_component
68805,GO:0031484,"A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.",myosin XIV complex,cellular_component
68806,GO:0031485,"A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.",myosin XV complex,cellular_component
68807,GO:0031486,A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.,myosin XVI complex,cellular_component
68808,GO:0031487,A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.,myosin XVII complex,cellular_component
68809,GO:0031488,A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.,myosin XVIII complex,cellular_component
68810,GO:0031489,Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.,myosin V binding,molecular_function
68811,GO:0031490,Binding to DNA that is assembled into chromatin.,chromatin DNA binding,molecular_function
68812,GO:0031491,"Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.",nucleosome binding,molecular_function
68813,GO:0031492,Binding to the DNA portion of a nucleosome.,nucleosomal DNA binding,molecular_function
68814,GO:0031494,"Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.",regulation of mating type switching,biological_process
68815,GO:0031495,"Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.",negative regulation of mating type switching,biological_process
68816,GO:0031496,"Any process that activates or increases the frequency, rate or extent of mating type switching.",positive regulation of mating type switching,biological_process
68817,GO:0031499,"A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance ...",TRAMP complex,cellular_component
68818,GO:0031500,A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.,Tea1 cell-end complex,cellular_component
68819,GO:0031501,A complex that possesses mannosyltransferase activity.,mannosyltransferase complex,cellular_component
68820,GO:0031502,A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.,dolichyl-phosphate-mannose-protein mannosyltransferase complex,cellular_component
68821,GO:0031503,"A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.",protein-containing complex localization,biological_process
68822,GO:0031504,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.",peptidoglycan-based cell wall organization,biological_process
68823,GO:0031505,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.",fungal-type cell wall organization,biological_process
68824,GO:0031506,"The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.",cell wall glycoprotein biosynthetic process,biological_process
68825,GO:0031507,"An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.",heterochromatin formation,biological_process
68826,GO:0031508,"The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.",pericentric heterochromatin formation,biological_process
68827,GO:0031509,The compaction of chromatin into heterochromatin at the subtelomeric region.,subtelomeric heterochromatin formation,biological_process
68828,GO:0031510,A conserved heterodimeric complex with SUMO activating enzyme activity.,SUMO activating enzyme complex,cellular_component
68829,GO:0031511,"A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.",Mis6-Sim4 complex,cellular_component
68830,GO:0031514,"A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found i...",motile cilium,cellular_component
68831,GO:0031515,"A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.",tRNA (m1A) methyltransferase complex,cellular_component
68832,GO:0031516,The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.,far-red light photoreceptor activity,molecular_function
68833,GO:0031517,The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.,red light photoreceptor activity,molecular_function
68834,GO:0031518,"A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.",CBF3 complex,cellular_component
68835,GO:0031519,"A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.",PcG protein complex,cellular_component
68836,GO:0031520,The portion of the plasma membrane surrounding the cell tip.,plasma membrane of cell tip,cellular_component
68837,GO:0031521,Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.,spitzenkorper,cellular_component
68838,GO:0031522,"A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.",cell envelope Sec protein transport complex,cellular_component
68839,GO:0031523,"A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.",Myb complex,cellular_component
68840,GO:0031525,"The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.",menthol biosynthetic process,biological_process
68841,GO:0031526,The portion of the plasma membrane surrounding the brush border.,brush border membrane,cellular_component
68842,GO:0031527,The portion of the plasma membrane surrounding a filopodium.,filopodium membrane,cellular_component
68843,GO:0031528,The portion of the plasma membrane surrounding a microvillus.,microvillus membrane,cellular_component
68844,GO:0031529,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.",ruffle organization,biological_process
68845,GO:0031530,"Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.",gonadotropin-releasing hormone receptor binding,molecular_function
68846,GO:0031531,"Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.",thyrotropin-releasing hormone receptor binding,molecular_function
68847,GO:0031533,A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.,mRNA capping enzyme complex,cellular_component
68848,GO:0031534,"The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.",minus-end directed microtubule sliding,biological_process
68849,GO:0031535,"The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.",plus-end directed microtubule sliding,biological_process
68850,GO:0031536,Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).,positive regulation of exit from mitosis,biological_process
68851,GO:0031537,"Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.",regulation of anthocyanin metabolic process,biological_process
68852,GO:0031538,"Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.",negative regulation of anthocyanin metabolic process,biological_process
68853,GO:0031539,"Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.",positive regulation of anthocyanin metabolic process,biological_process
68854,GO:0031540,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.",regulation of anthocyanin biosynthetic process,biological_process
68855,GO:0031541,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.",negative regulation of anthocyanin biosynthetic process,biological_process
68856,GO:0031542,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.",positive regulation of anthocyanin biosynthetic process,biological_process
68857,GO:0031543,Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.,peptidyl-proline dioxygenase activity,molecular_function
68858,GO:0031544,Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.,peptidyl-proline 3-dioxygenase activity,molecular_function
68859,GO:0031545,Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.,peptidyl-proline 4-dioxygenase activity,molecular_function
68860,GO:0031546,Binding to a brain-derived neurotrophic factor receptor.,brain-derived neurotrophic factor receptor binding,molecular_function
68861,GO:0031547,The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.,brain-derived neurotrophic factor receptor signaling pathway,biological_process
68862,GO:0031548,"Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.",regulation of brain-derived neurotrophic factor receptor signaling pathway,biological_process
68863,GO:0031549,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.",negative regulation of brain-derived neurotrophic factor receptor signaling pathway,biological_process
68864,GO:0031550,"Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.",positive regulation of brain-derived neurotrophic factor receptor signaling pathway,biological_process
68865,GO:0031554,"Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.",regulation of termination of DNA-templated transcription,biological_process
68866,GO:0031555,A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.,transcriptional attenuation,biological_process
68867,GO:0031556,"A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of t...",transcriptional attenuation by ribosome,biological_process
68868,GO:0031559,"Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.",oxidosqualene cyclase activity,molecular_function
68869,GO:0031560,"Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.",cellular bud neck polarisome,cellular_component
68870,GO:0031561,"Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.",cellular bud tip polarisome,cellular_component
68871,GO:0031562,"Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.",hyphal tip polarisome,cellular_component
68872,GO:0031563,"Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.",mating projection tip polarisome,cellular_component
68873,GO:0031564,"A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.",transcription antitermination,biological_process
68874,GO:0031566,The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.,actomyosin contractile ring maturation,biological_process
68875,GO:0031567,A signal transduction process that contributes to a cell size control checkpoint during mitosis.,mitotic cell size control checkpoint signaling,biological_process
68876,GO:0031568,A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.,mitotic G1 cell size control checkpoint signaling,biological_process
68877,GO:0031569,A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.,mitotic G2 cell size control checkpoint signaling,biological_process
68878,GO:0031570,"A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.",DNA integrity checkpoint signaling,biological_process
68879,GO:0031571,A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.,mitotic G1 DNA damage checkpoint signaling,biological_process
68880,GO:0031573,A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.,mitotic intra-S DNA damage checkpoint signaling,biological_process
68881,GO:0031577,A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.,spindle checkpoint signaling,biological_process
68882,GO:0031578,A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.,mitotic spindle orientation checkpoint signaling,biological_process
68883,GO:0031579,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.",membrane raft organization,biological_process
68884,GO:0031580,The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.,membrane raft distribution,biological_process
68885,GO:0031581,"Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.",hemidesmosome assembly,biological_process
68886,GO:0031582,A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.,replication fork arrest at rDNA repeats,biological_process
68887,GO:0031583,A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase D (PLD) and a subsequent increase in the intracellular concentration of phosphatidic acid (PA).,phospholipase D-activating G protein-coupled receptor signaling pathway,biological_process
68888,GO:0031588,A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).,nucleotide-activated protein kinase complex,cellular_component
68889,GO:0031589,The attachment of a cell to the underlying substrate via adhesion molecules.,cell-substrate adhesion,biological_process
68890,GO:0031591,"The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.",wybutosine biosynthetic process,biological_process
68891,GO:0031592,"An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.",centrosomal corona,cellular_component
68892,GO:0031593,Binding to a protein upon poly-ubiquitination of the target protein.,polyubiquitin modification-dependent protein binding,molecular_function
68893,GO:0031594,"The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.",neuromuscular junction,cellular_component
68894,GO:0031595,A proteasome found in the nucleus of a cell.,nuclear proteasome complex,cellular_component
68895,GO:0031597,A proteasome complex found in the cytosol of a cell.,cytosolic proteasome complex,cellular_component
68896,GO:0031598,The regulatory subcomplex of a proteasome located in the nucleus of a cell.,nuclear proteasome regulatory particle,cellular_component
68897,GO:0031600,"A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.",cytosolic proteasome regulatory particle,cellular_component
68898,GO:0031601,The core complex of a proteasome located in the nucleus of a cell.,nuclear proteasome core complex,cellular_component
68899,GO:0031603,The core complex of a proteasome located in the cytosol of a cell.,cytosolic proteasome core complex,cellular_component
68900,GO:0031604,The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.,"nuclear proteasome core complex, alpha-subunit complex",cellular_component
68901,GO:0031606,The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.,"cytosolic proteasome core complex, alpha-subunit complex",cellular_component
68902,GO:0031607,The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.,"nuclear proteasome core complex, beta-subunit complex",cellular_component
68903,GO:0031609,The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.,"cytosolic proteasome core complex, beta-subunit complex",cellular_component
68904,GO:0031610,The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.,"nuclear proteasome regulatory particle, base subcomplex",cellular_component
68905,GO:0031612,The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.,"cytosolic proteasome regulatory particle, base subcomplex",cellular_component
68906,GO:0031613,The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.,"nuclear proteasome regulatory particle, lid subcomplex",cellular_component
68907,GO:0031615,"The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.","cytosolic proteasome regulatory particle, lid subcomplex",cellular_component
68908,GO:0031616,A centrosome from which one pole of a mitotic or meiotic spindle is organized.,spindle pole centrosome,cellular_component
68909,GO:0031619,The cell cycle process in which the sister centromeres and kinetochores of one chromosome are fused and orientated so the chromosomes attach to microtubules that emanate from the same spindle pole. This process ensures that homologous l chromosomes are segregated at anaphase of meiosis I.,homologous chromosome orientation in meiotic metaphase I,biological_process
68910,GO:0031620,Any process that modulates the rate or extent of fever generation.,regulation of fever generation,biological_process
68911,GO:0031621,"Any process that stops, prevents, or reduces the rate or extent of fever generation.",negative regulation of fever generation,biological_process
68912,GO:0031622,"Any process that activates or increases the frequency, rate, or extent of fever generation.",positive regulation of fever generation,biological_process
68913,GO:0031623,A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.,receptor internalization,biological_process
68914,GO:0031624,"Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.",ubiquitin conjugating enzyme binding,molecular_function
68915,GO:0031625,"Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.",ubiquitin protein ligase binding,molecular_function
68916,GO:0031626,"Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.",beta-endorphin binding,molecular_function
68917,GO:0031627,"The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.",telomeric loop formation,biological_process
68918,GO:0031628,Binding to an opioid receptor.,opioid receptor binding,molecular_function
68919,GO:0031629,"Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.",synaptic vesicle fusion to presynaptic active zone membrane,biological_process
68920,GO:0031630,"Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.",regulation of synaptic vesicle fusion to presynaptic active zone membrane,biological_process
68921,GO:0031631,"Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.",negative regulation of synaptic vesicle fusion to presynaptic active zone membrane,biological_process
68922,GO:0031632,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.",positive regulation of synaptic vesicle fusion to presynaptic active zone membrane,biological_process
68923,GO:0031633,A chromatophore containing yellow pigment.,xanthophore,cellular_component
68924,GO:0031634,"Binding to replication fork barriers, sites that inhibit the progress of replication forks.",replication fork barrier binding,molecular_function
68925,GO:0031635,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting opioid receptor signaling pathway,biological_process
68926,GO:0031637,"The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.",regulation of neuronal synaptic plasticity in response to neurotrophin,biological_process
68927,GO:0031638,The proteolytic processing of an inactive enzyme to an active form.,zymogen activation,biological_process
68928,GO:0031639,"The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.",plasminogen activation,biological_process
68929,GO:0031640,"Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.",killing of cells of another organism,biological_process
68930,GO:0031641,"Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.",regulation of myelination,biological_process
68931,GO:0031642,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.",negative regulation of myelination,biological_process
68932,GO:0031643,"Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.",positive regulation of myelination,biological_process
68933,GO:0031644,"Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.",regulation of nervous system process,biological_process
68934,GO:0031645,"Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.",negative regulation of nervous system process,biological_process
68935,GO:0031646,"Any process that activates or increases the frequency, rate or extent of a neurophysiological process.",positive regulation of nervous system process,biological_process
68936,GO:0031647,"Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.",regulation of protein stability,biological_process
68937,GO:0031648,"Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.",protein destabilization,biological_process
68938,GO:0031649,"Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.",heat generation,biological_process
68939,GO:0031650,Any process that modulates the rate or extent of heat generation.,regulation of heat generation,biological_process
68940,GO:0031651,"Any process that stops, prevents, or reduces the rate or extent of heat generation.",negative regulation of heat generation,biological_process
68941,GO:0031652,Any process that activates or increases the rate or extent of heat generation.,positive regulation of heat generation,biological_process
68942,GO:0031653,"Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.",heat dissipation,biological_process
68943,GO:0031654,Any process that modulates the rate or extent of heat dissipation.,regulation of heat dissipation,biological_process
68944,GO:0031655,"Any process that stops, prevents, or reduces the rate or extent of heat dissipation.",negative regulation of heat dissipation,biological_process
68945,GO:0031656,Any process that activates or increases the rate or extent of heat dissipation.,positive regulation of heat dissipation,biological_process
68946,GO:0031663,"The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.",lipopolysaccharide-mediated signaling pathway,biological_process
68947,GO:0031664,"Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.",regulation of lipopolysaccharide-mediated signaling pathway,biological_process
68948,GO:0031665,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.",negative regulation of lipopolysaccharide-mediated signaling pathway,biological_process
68949,GO:0031666,"Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.",positive regulation of lipopolysaccharide-mediated signaling pathway,biological_process
68950,GO:0031667,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.",response to nutrient levels,biological_process
68951,GO:0031669,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.",cellular response to nutrient levels,biological_process
68952,GO:0031670,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.",cellular response to nutrient,biological_process
68953,GO:0031671,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.",primary cell septum biogenesis,biological_process
68954,GO:0031672,"The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.",A band,cellular_component
68955,GO:0031673,"A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.",H zone,cellular_component
68956,GO:0031674,"A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.",I band,cellular_component
68957,GO:0031676,The pigmented membrane of a plasma membrane-derived thylakoid.,plasma membrane-derived thylakoid membrane,cellular_component
68958,GO:0031680,"The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.",G-protein beta/gamma-subunit complex,cellular_component
68959,GO:0031681,Binding to a G-protein beta subunit.,G-protein beta-subunit binding,molecular_function
68960,GO:0031682,Binding to a G-protein gamma subunit.,G-protein gamma-subunit binding,molecular_function
68961,GO:0031683,Binding to a complex of G-protein beta/gamma subunits.,G-protein beta/gamma-subunit complex binding,molecular_function
68962,GO:0031685,Binding to an adenosine receptor.,adenosine receptor binding,molecular_function
68963,GO:0031686,Binding to an A1 adenosine receptor.,A1 adenosine receptor binding,molecular_function
68964,GO:0031687,Binding to an A2A adenosine receptor.,A2A adenosine receptor binding,molecular_function
68965,GO:0031688,Binding to an A2B adenosine receptor.,A2B adenosine receptor binding,molecular_function
68966,GO:0031689,Binding to an A3 adenosine receptor.,A3 adenosine receptor binding,molecular_function
68967,GO:0031690,Binding to an adrenergic receptor.,adrenergic receptor binding,molecular_function
68968,GO:0031691,Binding to an alpha-1A adrenergic receptor.,alpha-1A adrenergic receptor binding,molecular_function
68969,GO:0031692,Binding to an alpha-1B adrenergic receptor.,alpha-1B adrenergic receptor binding,molecular_function
68970,GO:0031693,Binding to an alpha-1D adrenergic receptor.,alpha-1D adrenergic receptor binding,molecular_function
68971,GO:0031694,Binding to an alpha-2A adrenergic receptor.,alpha-2A adrenergic receptor binding,molecular_function
68972,GO:0031695,Binding to an alpha-2B adrenergic receptor.,alpha-2B adrenergic receptor binding,molecular_function
68973,GO:0031696,Binding to an alpha-2C adrenergic receptor.,alpha-2C adrenergic receptor binding,molecular_function
68974,GO:0031697,Binding to a beta-1 adrenergic receptor.,beta-1 adrenergic receptor binding,molecular_function
68975,GO:0031698,Binding to a beta-2 adrenergic receptor.,beta-2 adrenergic receptor binding,molecular_function
68976,GO:0031699,Binding to a beta-3 adrenergic receptor.,beta-3 adrenergic receptor binding,molecular_function
68977,GO:0031700,Binding to an adrenomedullin receptor.,adrenomedullin receptor binding,molecular_function
68978,GO:0031701,Binding to an angiotensin receptor.,angiotensin receptor binding,molecular_function
68979,GO:0031702,Binding to a type 1 angiotensin receptor.,type 1 angiotensin receptor binding,molecular_function
68980,GO:0031703,Binding to a type 2 angiotensin receptor.,type 2 angiotensin receptor binding,molecular_function
68981,GO:0031704,Binding to an apelin receptor.,apelin receptor binding,molecular_function
68982,GO:0031705,Binding to a bombesin receptor.,bombesin receptor binding,molecular_function
68983,GO:0031706,Binding to a subtype 3 bombesin receptor.,subtype 3 bombesin receptor binding,molecular_function
68984,GO:0031707,Binding to an endothelin A receptor.,endothelin A receptor binding,molecular_function
68985,GO:0031708,Binding to an endothelin B receptor.,endothelin B receptor binding,molecular_function
68986,GO:0031709,Binding to a gastrin-releasing peptide receptor.,gastrin-releasing peptide receptor binding,molecular_function
68987,GO:0031710,Binding to a neuromedin B receptor.,neuromedin B receptor binding,molecular_function
68988,GO:0031711,Binding to a bradykinin receptor.,bradykinin receptor binding,molecular_function
68989,GO:0031712,Binding to a B1 bradykinin receptor.,B1 bradykinin receptor binding,molecular_function
68990,GO:0031713,Binding to a B2 bradykinin receptor.,B2 bradykinin receptor binding,molecular_function
68991,GO:0031714,Binding to a C5a anaphylatoxin chemotactic receptor.,C5a anaphylatoxin chemotactic receptor binding,molecular_function
68992,GO:0031715,Binding to a C5L2 anaphylatoxin chemotactic receptor.,C5L2 anaphylatoxin chemotactic receptor binding,molecular_function
68993,GO:0031716,Binding to a calcitonin receptor.,calcitonin receptor binding,molecular_function
68994,GO:0031717,Binding to a cannabinoid receptor.,cannabinoid receptor binding,molecular_function
68995,GO:0031718,Binding to a type 1 cannabinoid receptor.,type 1 cannabinoid receptor binding,molecular_function
68996,GO:0031719,Binding to a type 2 cannabinoid receptor.,type 2 cannabinoid receptor binding,molecular_function
68997,GO:0031720,"Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.",haptoglobin binding,molecular_function
68998,GO:0031721,Binding to a hemoglobin alpha chain.,hemoglobin alpha binding,molecular_function
68999,GO:0031722,Binding to a hemoglobin beta chain.,hemoglobin beta binding,molecular_function
69000,GO:0031723,Binding to a CXCR4 chemokine receptor.,CXCR4 chemokine receptor binding,molecular_function
69001,GO:0031724,Binding to a CXCR5 chemokine receptor.,CXCR5 chemokine receptor binding,molecular_function
69002,GO:0031725,Binding to a CXCR6 chemokine receptor.,CXCR6 chemokine receptor binding,molecular_function
69003,GO:0031726,Binding to a CCR1 chemokine receptor.,CCR1 chemokine receptor binding,molecular_function
69004,GO:0031727,Binding to a CCR2 chemokine receptor.,CCR2 chemokine receptor binding,molecular_function
69005,GO:0031728,Binding to a CCR3 chemokine receptor.,CCR3 chemokine receptor binding,molecular_function
69006,GO:0031729,Binding to a CCR4 chemokine receptor.,CCR4 chemokine receptor binding,molecular_function
69007,GO:0031730,Binding to a CCR5 chemokine receptor.,CCR5 chemokine receptor binding,molecular_function
69008,GO:0031731,Binding to a CCR6 chemokine receptor.,CCR6 chemokine receptor binding,molecular_function
69009,GO:0031732,Binding to a CCR7 chemokine receptor.,CCR7 chemokine receptor binding,molecular_function
69010,GO:0031733,Binding to a CCR8 chemokine receptor.,CCR8 chemokine receptor binding,molecular_function
69011,GO:0031734,Binding to a CCR9 chemokine receptor.,CCR9 chemokine receptor binding,molecular_function
69012,GO:0031735,Binding to a CCR10 chemokine receptor.,CCR10 chemokine receptor binding,molecular_function
69013,GO:0031736,Binding to a CCR11 chemokine receptor.,CCR11 chemokine receptor binding,molecular_function
69014,GO:0031737,Binding to a CX3C chemokine receptor.,CX3C chemokine receptor binding,molecular_function
69015,GO:0031738,Binding to a XCR1 chemokine receptor.,XCR1 chemokine receptor binding,molecular_function
69016,GO:0031739,Binding to a cholecystokinin receptor.,cholecystokinin receptor binding,molecular_function
69017,GO:0031740,Binding to a type A cholecystokinin receptor.,type A cholecystokinin receptor binding,molecular_function
69018,GO:0031741,Binding to a type B gastrin/cholecystokinin receptor.,type B gastrin/cholecystokinin receptor binding,molecular_function
69019,GO:0031745,Binding to a cysteinyl leukotriene receptor.,cysteinyl leukotriene receptor binding,molecular_function
69020,GO:0031746,Binding to a type 1 cysteinyl leukotriene receptor.,type 1 cysteinyl leukotriene receptor binding,molecular_function
69021,GO:0031747,Binding to a type 2 cysteinyl leukotriene receptor.,type 2 cysteinyl leukotriene receptor binding,molecular_function
69022,GO:0031748,Binding to a D1 dopamine receptor.,D1 dopamine receptor binding,molecular_function
69023,GO:0031749,Binding to a D2 dopamine receptor.,D2 dopamine receptor binding,molecular_function
69024,GO:0031750,Binding to a D3 dopamine receptor.,D3 dopamine receptor binding,molecular_function
69025,GO:0031751,Binding to a D4 dopamine receptor.,D4 dopamine receptor binding,molecular_function
69026,GO:0031752,Binding to a D5 dopamine receptor.,D5 dopamine receptor binding,molecular_function
69027,GO:0031753,Binding to an endothelial differentiation G protein-coupled receptor.,endothelial differentiation G protein-coupled receptor binding,molecular_function
69028,GO:0031754,Binding to an Edg-1 sphingosine 1-phosphate receptor.,Edg-1 sphingosine 1-phosphate receptor binding,molecular_function
69029,GO:0031755,Binding to an Edg-2 lysophosphatidic acid receptor.,Edg-2 lysophosphatidic acid receptor binding,molecular_function
69030,GO:0031756,Binding to an Edg-3 sphingosine 1-phosphate receptor.,Edg-3 sphingosine 1-phosphate receptor binding,molecular_function
69031,GO:0031757,Binding to an Edg-4 lysophosphatidic acid receptor.,Edg-4 lysophosphatidic acid receptor binding,molecular_function
69032,GO:0031758,Binding to an Edg-5 sphingosine 1-phosphate receptor.,Edg-5 sphingosine 1-phosphate receptor binding,molecular_function
69033,GO:0031759,Binding to an Edg-6 sphingosine 1-phosphate receptor.,Edg-6 sphingosine 1-phosphate receptor binding,molecular_function
69034,GO:0031760,Binding to an Edg-7 lysophosphatidic acid receptor.,Edg-7 lysophosphatidic acid receptor binding,molecular_function
69035,GO:0031761,Binding to a fMet-Leu-Phe receptor.,fMet-Leu-Phe receptor binding,molecular_function
69036,GO:0031762,Binding to a follicle-stimulating hormone receptor.,follicle-stimulating hormone receptor binding,molecular_function
69037,GO:0031763,Binding to a galanin receptor.,galanin receptor binding,molecular_function
69038,GO:0031764,Binding to a type 1 galanin receptor.,type 1 galanin receptor binding,molecular_function
69039,GO:0031765,Binding to a type 2 galanin receptor.,type 2 galanin receptor binding,molecular_function
69040,GO:0031766,Binding to a type 3 galanin receptor.,type 3 galanin receptor binding,molecular_function
69041,GO:0031767,Binding to a gastric inhibitory polypeptide receptor.,gastric inhibitory polypeptide receptor binding,molecular_function
69042,GO:0031768,Binding to a ghrelin receptor.,ghrelin receptor binding,molecular_function
69043,GO:0031769,Binding to a glucagon receptor.,glucagon receptor binding,molecular_function
69044,GO:0031770,Binding to a growth hormone-releasing hormone receptor.,growth hormone-releasing hormone receptor binding,molecular_function
69045,GO:0031771,Binding to a type 1 orexin receptor.,type 1 orexin receptor binding,molecular_function
69046,GO:0031772,Binding to a type 2 orexin receptor.,type 2 orexin receptor binding,molecular_function
69047,GO:0031773,Binding to a kisspeptin receptor.,kisspeptin receptor binding,molecular_function
69048,GO:0031774,Binding to a leukotriene receptor.,leukotriene receptor binding,molecular_function
69049,GO:0031775,Binding to a lutropin-choriogonadotropic hormone receptor.,lutropin-choriogonadotropic hormone receptor binding,molecular_function
69050,GO:0031776,Binding to a melanin-concentrating hormone receptor.,melanin-concentrating hormone receptor binding,molecular_function
69051,GO:0031777,Binding to a type 1 melanin-concentrating hormone receptor.,type 1 melanin-concentrating hormone receptor binding,molecular_function
69052,GO:0031778,Binding to a type 2 melanin-concentrating hormone receptor.,type 2 melanin-concentrating hormone receptor binding,molecular_function
69053,GO:0031779,Binding to a melanocortin receptor.,melanocortin receptor binding,molecular_function
69054,GO:0031780,Binding to a corticotropin hormone receptor.,corticotropin hormone receptor binding,molecular_function
69055,GO:0031781,Binding to a type 3 melanocortin receptor.,type 3 melanocortin receptor binding,molecular_function
69056,GO:0031782,Binding to a type 4 melanocortin receptor.,type 4 melanocortin receptor binding,molecular_function
69057,GO:0031783,Binding to a type 5 melanocortin receptor.,type 5 melanocortin receptor binding,molecular_function
69058,GO:0031784,Binding to a melatonin receptor.,melatonin receptor binding,molecular_function
69059,GO:0031785,Binding to a type 1A melatonin receptor.,type 1A melatonin receptor binding,molecular_function
69060,GO:0031786,Binding to a type 1B melatonin receptor.,type 1B melatonin receptor binding,molecular_function
69061,GO:0031787,Binding to a H9 melatonin receptor.,H9 melatonin receptor binding,molecular_function
69062,GO:0031788,Binding to a motilin receptor.,motilin receptor binding,molecular_function
69063,GO:0031789,Binding to a G protein-coupled acetylcholine receptor.,G protein-coupled acetylcholine receptor binding,molecular_function
69064,GO:0031795,Binding to a G protein-coupled (metabotropic) GABA receptor.,G protein-coupled GABA receptor binding,molecular_function
69065,GO:0031796,Binding to a type 1 metabotropic GABA receptor.,type 1 metabotropic GABA receptor binding,molecular_function
69066,GO:0031797,Binding to a type 2 metabotropic GABA receptor.,type 2 metabotropic GABA receptor binding,molecular_function
69067,GO:0031798,Binding to a type 1 metabotropic glutamate receptor.,type 1 metabotropic glutamate receptor binding,molecular_function
69068,GO:0031799,Binding to a type 2 metabotropic glutamate receptor.,type 2 metabotropic glutamate receptor binding,molecular_function
69069,GO:0031800,Binding to a type 3 metabotropic glutamate receptor.,type 3 metabotropic glutamate receptor binding,molecular_function
69070,GO:0031801,Binding to a type 4 metabotropic glutamate receptor.,type 4 metabotropic glutamate receptor binding,molecular_function
69071,GO:0031802,Binding to a type 5 metabotropic glutamate receptor.,type 5 metabotropic glutamate receptor binding,molecular_function
69072,GO:0031803,Binding to a type 6 metabotropic glutamate receptor.,type 6 metabotropic glutamate receptor binding,molecular_function
69073,GO:0031804,Binding to a type 7 metabotropic glutamate receptor.,type 7 metabotropic glutamate receptor binding,molecular_function
69074,GO:0031805,Binding to a type 8 metabotropic glutamate receptor.,type 8 metabotropic glutamate receptor binding,molecular_function
69075,GO:0031806,Binding to a G protein-coupled (metabotropic) histamine receptor.,G protein-coupled histamine receptor binding,molecular_function
69076,GO:0031807,Binding to a H1 histamine receptor.,H1 histamine receptor binding,molecular_function
69077,GO:0031808,Binding to a H2 histamine receptor.,H2 histamine receptor binding,molecular_function
69078,GO:0031809,Binding to a H3 histamine receptor.,H3 histamine receptor binding,molecular_function
69079,GO:0031810,Binding to a H4 histamine receptor.,H4 histamine receptor binding,molecular_function
69080,GO:0031811,Binding to a G protein-coupled (metabotropic) nucleotide receptor.,G protein-coupled nucleotide receptor binding,molecular_function
69081,GO:0031812,Binding to a P2Y1 nucleotide receptor.,P2Y1 nucleotide receptor binding,molecular_function
69082,GO:0031813,Binding to a P2Y2 nucleotide receptor.,P2Y2 nucleotide receptor binding,molecular_function
69083,GO:0031814,Binding to a P2Y4 nucleotide receptor.,P2Y4 nucleotide receptor binding,molecular_function
69084,GO:0031815,Binding to a P2Y5 nucleotide receptor.,P2Y5 nucleotide receptor binding,molecular_function
69085,GO:0031816,Binding to a P2Y6 nucleotide receptor.,P2Y6 nucleotide receptor binding,molecular_function
69086,GO:0031817,Binding to a P2Y8 nucleotide receptor.,P2Y8 nucleotide receptor binding,molecular_function
69087,GO:0031818,Binding to a P2Y9 nucleotide receptor.,P2Y9 nucleotide receptor binding,molecular_function
69088,GO:0031819,Binding to a P2Y10 nucleotide receptor.,P2Y10 nucleotide receptor binding,molecular_function
69089,GO:0031820,Binding to a P2Y11 nucleotide receptor.,P2Y11 nucleotide receptor binding,molecular_function
69090,GO:0031821,Binding to a metabotropic serotonin receptor.,G protein-coupled serotonin receptor binding,molecular_function
69091,GO:0031822,Binding to a type 1B serotonin receptor.,type 1B serotonin receptor binding,molecular_function
69092,GO:0031823,Binding to a type 1D serotonin receptor.,type 1D serotonin receptor binding,molecular_function
69093,GO:0031824,Binding to a type 1E serotonin receptor.,type 1E serotonin receptor binding,molecular_function
69094,GO:0031825,Binding to a type 1F serotonin receptor.,type 1F serotonin receptor binding,molecular_function
69095,GO:0031826,Binding to a type 2A serotonin receptor.,type 2A serotonin receptor binding,molecular_function
69096,GO:0031827,Binding to a type 2B serotonin receptor.,type 2B serotonin receptor binding,molecular_function
69097,GO:0031828,Binding to a type 2C serotonin receptor.,type 2C serotonin receptor binding,molecular_function
69098,GO:0031829,Binding to a type 4 serotonin receptor.,type 4 serotonin receptor binding,molecular_function
69099,GO:0031830,Binding to a type 5A serotonin receptor.,type 5A serotonin receptor binding,molecular_function
69100,GO:0031831,Binding to a type 5B serotonin receptor.,type 5B serotonin receptor binding,molecular_function
69101,GO:0031832,Binding to a type 6 serotonin receptor.,type 6 serotonin receptor binding,molecular_function
69102,GO:0031833,Binding to a type 7 serotonin receptor.,type 7 serotonin receptor binding,molecular_function
69103,GO:0031834,Binding to a neurokinin receptor.,neurokinin receptor binding,molecular_function
69104,GO:0031835,Binding to a substance P receptor.,substance P receptor binding,molecular_function
69105,GO:0031836,Binding to a neuromedin K receptor.,neuromedin K receptor binding,molecular_function
69106,GO:0031837,Binding to a substance K receptor.,substance K receptor binding,molecular_function
69107,GO:0031838,A protein complex formed by the stable binding of a haptoglobin to hemoglobin.,haptoglobin-hemoglobin complex,cellular_component
69108,GO:0031839,Binding to a type 1 neuromedin U receptor.,type 1 neuromedin U receptor binding,molecular_function
69109,GO:0031840,Binding to a type 2 neuromedin U receptor.,type 2 neuromedin U receptor binding,molecular_function
69110,GO:0031841,Binding to a neuropeptide Y receptor.,neuropeptide Y receptor binding,molecular_function
69111,GO:0031842,Binding to a type 1 neuropeptide Y receptor.,type 1 neuropeptide Y receptor binding,molecular_function
69112,GO:0031843,Binding to a type 2 neuropeptide Y receptor.,type 2 neuropeptide Y receptor binding,molecular_function
69113,GO:0031844,Binding to a type 4 neuropeptide Y receptor.,type 4 neuropeptide Y receptor binding,molecular_function
69114,GO:0031845,Binding to a type 5 neuropeptide Y receptor.,type 5 neuropeptide Y receptor binding,molecular_function
69115,GO:0031846,Binding to a neurotensin receptor.,neurotensin receptor binding,molecular_function
69116,GO:0031847,Binding to a type 1 neurotensin receptor.,type 1 neurotensin receptor binding,molecular_function
69117,GO:0031848,"A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.",protection from non-homologous end joining at telomere,biological_process
69118,GO:0031849,Binding to an olfactory receptor.,olfactory receptor binding,molecular_function
69119,GO:0031850,Binding to a delta-type opioid receptor.,delta-type opioid receptor binding,molecular_function
69120,GO:0031851,Binding to a kappa-type opioid receptor.,kappa-type opioid receptor binding,molecular_function
69121,GO:0031852,Binding to a mu-type opioid receptor.,mu-type opioid receptor binding,molecular_function
69122,GO:0031853,Binding to a nociceptin receptor.,nociceptin receptor binding,molecular_function
69123,GO:0031854,Binding to an orexigenic neuropeptide QRFP receptor.,orexigenic neuropeptide QRFP receptor binding,molecular_function
69124,GO:0031855,Binding to an oxytocin receptor.,oxytocin receptor binding,molecular_function
69125,GO:0031856,Binding to a parathyroid hormone receptor.,parathyroid hormone receptor binding,molecular_function
69126,GO:0031857,Binding to a type 1 parathyroid hormone receptor.,type 1 parathyroid hormone receptor binding,molecular_function
69127,GO:0031858,Binding to a pituitary adenylate cyclase-activating polypeptide receptor.,pituitary adenylate cyclase-activating polypeptide receptor binding,molecular_function
69128,GO:0031859,Binding to a platelet activating factor receptor.,platelet activating factor receptor binding,molecular_function
69129,GO:0031860,"The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.",telomeric 3' overhang formation,biological_process
69130,GO:0031861,Binding to a prolactin-releasing peptide receptor.,prolactin-releasing peptide receptor binding,molecular_function
69131,GO:0031862,Binding to a prostanoid receptor.,prostanoid receptor binding,molecular_function
69132,GO:0031863,Binding to a prostaglandin D2 receptor.,prostaglandin D2 receptor binding,molecular_function
69133,GO:0031864,Binding to an EP1 subtype prostaglandin E2 receptor.,EP1 subtype prostaglandin E2 receptor binding,molecular_function
69134,GO:0031865,Binding to an EP2 subtype prostaglandin E2 receptor.,EP2 subtype prostaglandin E2 receptor binding,molecular_function
69135,GO:0031866,Binding to an EP3 subtype prostaglandin E2 receptor.,EP3 subtype prostaglandin E2 receptor binding,molecular_function
69136,GO:0031867,Binding to an EP4 subtype prostaglandin E2 receptor.,EP4 subtype prostaglandin E2 receptor binding,molecular_function
69137,GO:0031868,Binding to a prostaglandin F2-alpha receptor.,prostaglandin F2-alpha receptor binding,molecular_function
69138,GO:0031869,Binding to a prostacyclin receptor.,prostacyclin receptor binding,molecular_function
69139,GO:0031870,Binding to a thromboxane A2 receptor.,thromboxane A2 receptor binding,molecular_function
69140,GO:0031871,Binding to a proteinase activated receptor.,proteinase activated receptor binding,molecular_function
69141,GO:0031872,Binding to a type 1 proteinase activated receptor.,type 1 proteinase activated receptor binding,molecular_function
69142,GO:0031873,Binding to a type 2 proteinase activated receptor.,type 2 proteinase activated receptor binding,molecular_function
69143,GO:0031874,Binding to a type 3 proteinase activated receptor.,type 3 proteinase activated receptor binding,molecular_function
69144,GO:0031875,Binding to a type 4 proteinase activated receptor.,type 4 proteinase activated receptor binding,molecular_function
69145,GO:0031876,Binding to a secretin receptor.,secretin receptor binding,molecular_function
69146,GO:0031877,Binding to a somatostatin receptor.,somatostatin receptor binding,molecular_function
69147,GO:0031878,Binding to a type 1 somatostatin receptor.,type 1 somatostatin receptor binding,molecular_function
69148,GO:0031879,Binding to a type 2 somatostatin receptor.,type 2 somatostatin receptor binding,molecular_function
69149,GO:0031880,Binding to a type 3 somatostatin receptor.,type 3 somatostatin receptor binding,molecular_function
69150,GO:0031881,Binding to a type 4 somatostatin receptor.,type 4 somatostatin receptor binding,molecular_function
69151,GO:0031882,Binding to a type 5 somatostatin receptor.,type 5 somatostatin receptor binding,molecular_function
69152,GO:0031883,Binding to a taste receptor.,taste receptor binding,molecular_function
69153,GO:0031884,Binding to a type 1 member 1 taste receptor.,type 1 member 1 taste receptor binding,molecular_function
69154,GO:0031885,Binding to a type 1 member 2 taste receptor.,type 1 member 2 taste receptor binding,molecular_function
69155,GO:0031886,Binding to a type 1 member 3 taste receptor.,type 1 member 3 taste receptor binding,molecular_function
69156,GO:0031887,"The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.",lipid droplet transport along microtubule,biological_process
69157,GO:0031889,Binding to a urotensin receptor.,urotensin receptor binding,molecular_function
69158,GO:0031890,Binding to a vasoactive intestinal polypeptide receptor.,vasoactive intestinal polypeptide receptor binding,molecular_function
69159,GO:0031891,Binding to a type 1 vasoactive intestinal polypeptide receptor.,type 1 vasoactive intestinal polypeptide receptor binding,molecular_function
69160,GO:0031892,Binding to a type 2 vasoactive intestinal polypeptide receptor.,type 2 vasoactive intestinal polypeptide receptor binding,molecular_function
69161,GO:0031893,Binding to a vasopressin receptor.,vasopressin receptor binding,molecular_function
69162,GO:0031894,Binding to a V1A vasopressin receptor.,V1A vasopressin receptor binding,molecular_function
69163,GO:0031895,Binding to a V1B vasopressin receptor.,V1B vasopressin receptor binding,molecular_function
69164,GO:0031896,Binding to a V2 vasopressin receptor.,V2 vasopressin receptor binding,molecular_function
69165,GO:0031897,"The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.",Tic complex,cellular_component
69166,GO:0031898,The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,chromoplast envelope,cellular_component
69167,GO:0031899,"The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.",chromoplast inner membrane,cellular_component
69168,GO:0031900,"The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.",chromoplast outer membrane,cellular_component
69169,GO:0031901,The lipid bilayer surrounding an early endosome.,early endosome membrane,cellular_component
69170,GO:0031902,The lipid bilayer surrounding a late endosome.,late endosome membrane,cellular_component
69171,GO:0031903,The lipid bilayer surrounding a microbody.,microbody membrane,cellular_component
69172,GO:0031904,The volume enclosed by the membrane of an endosome.,endosome lumen,cellular_component
69173,GO:0031905,The volume enclosed by the membrane of an early endosome.,early endosome lumen,cellular_component
69174,GO:0031906,The volume enclosed by the membrane of a late endosome.,late endosome lumen,cellular_component
69175,GO:0031907,The volume enclosed by the membranes of a microbody.,microbody lumen,cellular_component
69176,GO:0031908,The volume enclosed by the membranes of a glyoxysome.,glyoxysomal lumen,cellular_component
69177,GO:0031910,"Stable, specialized structure for the ingestion of food by the cell into phagosomes.",cytostome,cellular_component
69178,GO:0031911,"Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.",cytoproct,cellular_component
69179,GO:0031912,Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.,oral apparatus,cellular_component
69180,GO:0031913,Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.,contractile vacuole pore,cellular_component
69181,GO:0031914,"A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.",negative regulation of synaptic plasticity,biological_process
69182,GO:0031915,"A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.",positive regulation of synaptic plasticity,biological_process
69183,GO:0031916,A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.,regulation of synaptic metaplasticity,biological_process
69184,GO:0031917,A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.,negative regulation of synaptic metaplasticity,biological_process
69185,GO:0031918,A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.,positive regulation of synaptic metaplasticity,biological_process
69186,GO:0031919,"The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",vitamin B6 transport,biological_process
69187,GO:0031920,"The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxal transport,biological_process
69188,GO:0031921,"The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.",pyridoxal phosphate transport,biological_process
69189,GO:0031922,"The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxamine transport,biological_process
69190,GO:0031923,"The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxine transport,biological_process
69191,GO:0031924,"Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other.",vitamin B6 transmembrane transporter activity,molecular_function
69192,GO:0031925,"Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxal transmembrane transporter activity,molecular_function
69193,GO:0031926,"Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.",pyridoxal phosphate transmembrane transporter activity,molecular_function
69194,GO:0031927,"Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxamine transmembrane transporter activity,molecular_function
69195,GO:0031928,"Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxine transmembrane transporter activity,molecular_function
69196,GO:0031929,"The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.",TOR signaling,biological_process
69197,GO:0031930,The series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.,mitochondria-nucleus signaling pathway,biological_process
69198,GO:0031931,"A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.",TORC1 complex,cellular_component
69199,GO:0031932,"A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.",TORC2 complex,cellular_component
69200,GO:0031934,Heterochromatic regions of the chromosome found at silenced mating-type loci.,mating-type region heterochromatin,cellular_component
69201,GO:0031941,A two-stranded helical polymer of the protein actin.,filamentous actin,cellular_component
69202,GO:0031942,Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.,i-AAA complex,cellular_component
69203,GO:0031943,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.",regulation of glucocorticoid metabolic process,biological_process
69204,GO:0031946,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.",regulation of glucocorticoid biosynthetic process,biological_process
69205,GO:0031947,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.",negative regulation of glucocorticoid biosynthetic process,biological_process
69206,GO:0031948,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.",positive regulation of glucocorticoid biosynthetic process,biological_process
69207,GO:0031949,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.",regulation of glucocorticoid catabolic process,biological_process
69208,GO:0031950,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.",negative regulation of glucocorticoid catabolic process,biological_process
69209,GO:0031951,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.",positive regulation of glucocorticoid catabolic process,biological_process
69210,GO:0031952,"Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.",regulation of protein autophosphorylation,biological_process
69211,GO:0031953,"Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.",negative regulation of protein autophosphorylation,biological_process
69212,GO:0031954,"Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.",positive regulation of protein autophosphorylation,biological_process
69213,GO:0031955,Catalysis of the reaction: a short-chain fatty acid + ATP + CoA = a short-chain fatty acyl-CoA + AMP + diphosphate. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid-CoA ligase activity,molecular_function
69214,GO:0031956,Catalysis of the reaction: a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid-CoA ligase activity,molecular_function
69215,GO:0031957,Catalysis of the reaction: a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acid-CoA ligase activity,molecular_function
69216,GO:0031958,"A nuclear receptor-mediated signaling pathway initiated by a corticosteroid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated corticosteroid signaling pathway,biological_process
69217,GO:0031959,"A nuclear receptor-mediated signaling pathway initiated by a mineralocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated mineralocorticoid signaling pathway,biological_process
69218,GO:0031960,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels...",response to corticosteroid,biological_process
69219,GO:0031961,Binding to a nuclear cortisol receptor.,nuclear cortisol receptor binding,molecular_function
69220,GO:0031962,Binding to a nuclear mineralocorticoid receptor.,nuclear mineralocorticoid receptor binding,molecular_function
69221,GO:0031963,A nuclear receptor activity regulated by cortisol binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.,nuclear cortisol receptor activity,molecular_function
69222,GO:0031964,Catalysis of the reaction: carcinine + H2O = histamine + beta-alanine. Carcinine is also known as N-beta-alanyl histamine.,beta-alanyl-histamine hydrolase activity,molecular_function
69223,GO:0031965,Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.,nuclear membrane,cellular_component
69224,GO:0031966,Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.,mitochondrial membrane,cellular_component
69225,GO:0031967,"A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.",organelle envelope,cellular_component
69226,GO:0031968,"The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.",organelle outer membrane,cellular_component
69227,GO:0031969,Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.,chloroplast membrane,cellular_component
69228,GO:0031970,The region between the inner and outer lipid bilayers of an organelle envelope.,organelle envelope lumen,cellular_component
69229,GO:0031972,The region between the inner and outer lipid bilayers of a chloroplast envelope.,chloroplast intermembrane space,cellular_component
69230,GO:0031973,The region between the inner and outer lipid bilayers of a chromoplast envelope.,chromoplast intermembrane space,cellular_component
69231,GO:0031974,"The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.",membrane-enclosed lumen,cellular_component
69232,GO:0031976,Any thylakoid within a plastid.,plastid thylakoid,cellular_component
69233,GO:0031977,The volume enclosed by a thylakoid membrane.,thylakoid lumen,cellular_component
69234,GO:0031978,The volume enclosed by a plastid thylakoid membrane.,plastid thylakoid lumen,cellular_component
69235,GO:0031979,The volume enclosed by a plasma membrane-derived thylakoid.,plasma membrane-derived thylakoid lumen,cellular_component
69236,GO:0031981,The volume enclosed by the nuclear inner membrane.,nuclear lumen,cellular_component
69237,GO:0031982,"Any small, fluid-filled, spherical organelle enclosed by membrane.",vesicle,cellular_component
69238,GO:0031983,The volume enclosed by the membrane or protein that forms a vesicle.,vesicle lumen,cellular_component
69239,GO:0031984,"A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.",organelle subcompartment,cellular_component
69240,GO:0031985,"Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.",Golgi cisterna,cellular_component
69241,GO:0031986,A leucoplast in which protein is stored.,proteinoplast,cellular_component
69242,GO:0031987,Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.,locomotion involved in locomotory behavior,biological_process
69243,GO:0031989,"A G protein-coupled receptor signaling pathway initiated by a bombesin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",bombesin receptor signaling pathway,biological_process
69244,GO:0031990,"The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.",mRNA export from nucleus in response to heat stress,biological_process
69245,GO:0031991,"Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.",regulation of actomyosin contractile ring contraction,biological_process
69246,GO:0031992,"The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.",energy transducer activity,molecular_function
69247,GO:0031993,"Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.",light transducer activity,molecular_function
69248,GO:0031994,Binding to insulin-like growth factor I.,insulin-like growth factor I binding,molecular_function
69249,GO:0031995,Binding to insulin-like growth factor II.,insulin-like growth factor II binding,molecular_function
69250,GO:0031996,Binding to a thioesterase.,thioesterase binding,molecular_function
69251,GO:0031998,"Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.",regulation of fatty acid beta-oxidation,biological_process
69252,GO:0031999,"Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.",negative regulation of fatty acid beta-oxidation,biological_process
69253,GO:0032000,"Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.",positive regulation of fatty acid beta-oxidation,biological_process
69254,GO:0032001,"Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.","1,4-alpha-glucan 6-alpha-glucosyltransferase activity",molecular_function
69255,GO:0032002,A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).,interleukin-28 receptor complex,cellular_component
69256,GO:0032003,Binding to an interleukin-28 receptor.,interleukin-28 receptor binding,molecular_function
69257,GO:0032006,"Any process that modulates the frequency, rate or extent of TOR signaling.",regulation of TOR signaling,biological_process
69258,GO:0032007,"Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.",negative regulation of TOR signaling,biological_process
69259,GO:0032008,"Any process that activates or increases the frequency, rate or extent of TOR signaling.",positive regulation of TOR signaling,biological_process
69260,GO:0032009,A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.,early phagosome,cellular_component
69261,GO:0032010,"A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.",phagolysosome,cellular_component
69262,GO:0032011,An intracellular signaling cassette in which a small monomeric GTPase of the ARF subfamily relays a signal.,ARF protein signal transduction,biological_process
69263,GO:0032012,"Any process that modulates the frequency, rate or extent of ARF protein signal transduction.",regulation of ARF protein signal transduction,biological_process
69264,GO:0032013,"Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.",negative regulation of ARF protein signal transduction,biological_process
69265,GO:0032014,"Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.",positive regulation of ARF protein signal transduction,biological_process
69266,GO:0032018,Catalysis of the reaction: 2-methylbutan-1-ol + NADP+ = 2-methylbutanal + NADPH + H+.,2-methylbutanal reductase (NADPH) activity,molecular_function
69267,GO:0032019,A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.,mitochondrial cloud,cellular_component
69268,GO:0032020,"The covalent addition to a protein of ISG15, a ubiquitin-like protein.",ISG15-protein conjugation,biological_process
69269,GO:0032021,"A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.",NELF complex,cellular_component
69270,GO:0032023,"The proteolytic processing of trypsinogen to the active form, trypsin.",trypsinogen activation,biological_process
69271,GO:0032024,"Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.",positive regulation of insulin secretion,biological_process
69272,GO:0032025,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion (Co2+) stimulus.",response to cobalt ion,biological_process
69273,GO:0032026,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.",response to magnesium ion,biological_process
69274,GO:0032027,Binding to a light chain of a myosin complex.,myosin light chain binding,molecular_function
69275,GO:0032028,Binding to the head/neck region of a myosin heavy chain.,myosin head/neck binding,molecular_function
69276,GO:0032029,Binding to the tail region of a myosin heavy chain.,myosin tail binding,molecular_function
69277,GO:0032030,Binding to a light chain of a myosin I complex.,myosin I light chain binding,molecular_function
69278,GO:0032031,Binding to the head/neck region of a myosin I heavy chain.,myosin I head/neck binding,molecular_function
69279,GO:0032032,Binding to the tail region of a myosin I heavy chain.,myosin I tail binding,molecular_function
69280,GO:0032033,Binding to a light chain of a myosin II complex.,myosin II light chain binding,molecular_function
69281,GO:0032034,Binding to the head/neck region of a myosin II heavy chain.,myosin II head/neck binding,molecular_function
69282,GO:0032035,Binding to the tail region of a myosin II heavy chain.,myosin II tail binding,molecular_function
69283,GO:0032036,Binding to a heavy chain of a myosin complex.,myosin heavy chain binding,molecular_function
69284,GO:0032037,Binding to a heavy chain of a myosin I complex.,myosin I heavy chain binding,molecular_function
69285,GO:0032038,Binding to a heavy chain of a myosin II complex.,myosin II heavy chain binding,molecular_function
69286,GO:0032039,A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.,integrator complex,cellular_component
69287,GO:0032040,"A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.",small-subunit processome,cellular_component
69288,GO:0032041,"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + NAD+ + H2O = histone H3 L-lysine (position 14) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K14 to NAD, producing nicotinamide.","histone H3K14 deacetylase activity, NAD-dependent",molecular_function
69289,GO:0032042,The chemical reactions and pathways involving mitochondrial DNA.,mitochondrial DNA metabolic process,biological_process
69290,GO:0032043,The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.,mitochondrial DNA catabolic process,biological_process
69291,GO:0032044,"A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.",DSIF complex,cellular_component
69292,GO:0032045,A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.,guanyl-nucleotide exchange factor complex,cellular_component
69293,GO:0032046,"A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.",micropexophagy-specific membrane apparatus,cellular_component
69294,GO:0032047,"A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.",mitosome,cellular_component
69295,GO:0032048,"The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.",cardiolipin metabolic process,biological_process
69296,GO:0032049,"The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.",cardiolipin biosynthetic process,biological_process
69297,GO:0032050,Binding to a clathrin heavy chain.,clathrin heavy chain binding,molecular_function
69298,GO:0032051,Binding to a clathrin light chain.,clathrin light chain binding,molecular_function
69299,GO:0032052,"Binding to a bile acid, a steroid carboxylic acids occurring in bile.",bile acid binding,molecular_function
69300,GO:0032053,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).",ciliary basal body organization,biological_process
69301,GO:0032055,"Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.",negative regulation of translation in response to stress,biological_process
69302,GO:0032056,"Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.",positive regulation of translation in response to stress,biological_process
69303,GO:0032057,"Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.",negative regulation of translational initiation in response to stress,biological_process
69304,GO:0032058,"Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.",positive regulation of translational initiation in response to stress,biological_process
69305,GO:0032059,"A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.",bleb,cellular_component
69306,GO:0032060,"The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.",bleb assembly,biological_process
69307,GO:0032061,"Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",negative regulation of translation in response to osmotic stress,biological_process
69308,GO:0032062,"Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",positive regulation of translation in response to osmotic stress,biological_process
69309,GO:0032063,"Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",negative regulation of translational initiation in response to osmotic stress,biological_process
69310,GO:0032064,"Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",positive regulation of translational initiation in response to osmotic stress,biological_process
69311,GO:0032065,A process in which a protein or protein complex is maintained in a specific location in the cell cortex.,maintenance of protein location in cell cortex,biological_process
69312,GO:0032067,"Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).",type IV site-specific deoxyribonuclease activity,molecular_function
69313,GO:0032068,"A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.",type IV site-specific deoxyribonuclease complex,cellular_component
69314,GO:0032071,"Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.",regulation of endodeoxyribonuclease activity,biological_process
69315,GO:0032077,"Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.",positive regulation of deoxyribonuclease activity,biological_process
69316,GO:0032079,"Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.",positive regulation of endodeoxyribonuclease activity,biological_process
69317,GO:0032089,"Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg2+-binding site and five more specific motifs.",NACHT domain binding,molecular_function
69318,GO:0032090,"Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.",Pyrin domain binding,molecular_function
69319,GO:0032091,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.",negative regulation of protein binding,biological_process
69320,GO:0032092,"Any process that activates or increases the frequency, rate or extent of protein binding.",positive regulation of protein binding,biological_process
69321,GO:0032093,"Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.",SAM domain binding,molecular_function
69322,GO:0032094,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.",response to food,biological_process
69323,GO:0032095,"Any process that modulates the frequency, rate or extent of a response to a food stimulus.",regulation of response to food,biological_process
69324,GO:0032096,"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.",negative regulation of response to food,biological_process
69325,GO:0032097,"Any process that activates, maintains, or increases the rate of a response to a food stimulus.",positive regulation of response to food,biological_process
69326,GO:0032098,"Any process which modulates appetite, the desire or physical craving for food.",regulation of appetite,biological_process
69327,GO:0032099,Any process that reduces appetite.,negative regulation of appetite,biological_process
69328,GO:0032100,Any process that increases appetite.,positive regulation of appetite,biological_process
69329,GO:0032101,"Any process that modulates the frequency, rate or extent of a response to an external stimulus.",regulation of response to external stimulus,biological_process
69330,GO:0032102,"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.",negative regulation of response to external stimulus,biological_process
69331,GO:0032103,"Any process that activates, maintains or increases the rate of a response to an external stimulus.",positive regulation of response to external stimulus,biological_process
69332,GO:0032107,"Any process that modulates the frequency, rate or extent of a response to nutrient levels.",regulation of response to nutrient levels,biological_process
69333,GO:0032108,"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.",negative regulation of response to nutrient levels,biological_process
69334,GO:0032109,"Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.",positive regulation of response to nutrient levels,biological_process
69335,GO:0032115,"Catalysis of the reaction: D-glucitol + NADP+ = L-sorbose + H+ + NADPH. The reaction may occur, to a minor extent, in the reverse direction.",sorbose reductase activity,molecular_function
69336,GO:0032116,"A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.",SMC loading complex,cellular_component
69337,GO:0032117,An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.,horsetail-astral microtubule array,cellular_component
69338,GO:0032118,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.",horsetail-astral microtubule organization,biological_process
69339,GO:0032120,"The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.",ascospore-type prospore membrane formation,biological_process
69340,GO:0032121,"The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.",meiotic attachment of telomeric heterochromatin to spindle pole body,biological_process
69341,GO:0032122,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.",oral apparatus organization,biological_process
69342,GO:0032123,"Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.",deep fiber,cellular_component
69343,GO:0032124,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.",macronucleus organization,biological_process
69344,GO:0032125,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.",micronucleus organization,biological_process
69345,GO:0032126,"A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.",eisosome,cellular_component
69346,GO:0032127,The lipid bilayer surrounding a dense core granule.,dense core granule membrane,cellular_component
69347,GO:0032129,Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.,"histone H3K9 deacetylase activity, hydrolytic mechanism",molecular_function
69348,GO:0032130,The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.,medial membrane band assembly,biological_process
69349,GO:0032131,Binding to an alkylated residue in DNA.,alkylated DNA binding,molecular_function
69350,GO:0032132,Binding to an O6-alkylguanine adduct in DNA.,O6-alkylguanine-DNA binding,molecular_function
69351,GO:0032133,"A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.",chromosome passenger complex,cellular_component
69352,GO:0032135,Binding to a double-stranded DNA region containing an insertion or a deletion.,DNA insertion or deletion binding,molecular_function
69353,GO:0032136,Binding to a double-stranded DNA region containing an A/C mispair.,adenine/cytosine mispair binding,molecular_function
69354,GO:0032137,Binding to a double-stranded DNA region containing a G/T mispair.,guanine/thymine mispair binding,molecular_function
69355,GO:0032138,Binding to a double-stranded DNA region containing a single base insertion or deletion.,single base insertion or deletion binding,molecular_function
69356,GO:0032139,Binding to a double-stranded DNA region containing a dinucleotide insertion or deletion.,dinucleotide insertion or deletion binding,molecular_function
69357,GO:0032140,Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine.,single adenine insertion binding,molecular_function
69358,GO:0032141,Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine.,single cytosine insertion binding,molecular_function
69359,GO:0032142,Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine.,single guanine insertion binding,molecular_function
69360,GO:0032143,Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine.,single thymine insertion binding,molecular_function
69361,GO:0032144,A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity.,4-aminobutyrate transaminase complex,cellular_component
69362,GO:0032145,Binding to succinate-semialdehyde dehydrogenase.,succinate-semialdehyde dehydrogenase binding,molecular_function
69363,GO:0032147,Any process that initiates the activity of an inactive protein kinase.,activation of protein kinase activity,biological_process
69364,GO:0032148,Any process that initiates the activity of the inactive enzyme protein kinase B.,activation of protein kinase B activity,biological_process
69365,GO:0032149,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.",response to rhamnose,biological_process
69366,GO:0032151,A heterooligomeric septin complex that acts during mitotic cell division.,mitotic septin complex,cellular_component
69367,GO:0032152,A heterooligomeric septin complex that acts during meiotic cell division.,meiotic septin complex,cellular_component
69368,GO:0032153,"The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.",cell division site,cellular_component
69369,GO:0032154,The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.,cleavage furrow,cellular_component
69370,GO:0032156,The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.,septin cytoskeleton,cellular_component
69371,GO:0032157,"A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.",prospore contractile ring,cellular_component
69372,GO:0032158,"A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.",septin band,cellular_component
69373,GO:0032159,A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.,septin cap,cellular_component
69374,GO:0032160,"Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.",septin filament array,cellular_component
69375,GO:0032161,Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.,cleavage apparatus septin structure,cellular_component
69376,GO:0032162,"A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).",mating projection septin band,cellular_component
69377,GO:0032163,"A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.",hyphal septin band,cellular_component
69378,GO:0032164,A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.,hyphal septin cap,cellular_component
69379,GO:0032165,"Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.",prospore septin filament array,cellular_component
69380,GO:0032166,"Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.",chlamydospore septin filament array,cellular_component
69381,GO:0032168,A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.,hyphal septin ring,cellular_component
69382,GO:0032169,A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.,prospore septin ring,cellular_component
69383,GO:0032170,A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.,pseudohyphal septin ring,cellular_component
69384,GO:0032171,A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.,germ tube septin cap,cellular_component
69385,GO:0032172,A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.,germ tube septin ring,cellular_component
69386,GO:0032173,"A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.",septin collar,cellular_component
69387,GO:0032174,"A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.",cellular bud neck septin collar,cellular_component
69388,GO:0032175,"A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.",mating projection septin ring,cellular_component
69389,GO:0032176,"A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.",split septin rings,cellular_component
69390,GO:0032177,Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.,cellular bud neck split septin rings,cellular_component
69391,GO:0032178,A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.,medial membrane band,cellular_component
69392,GO:0032179,The slender tubular outgrowth first produced by most spores in germination.,germ tube,cellular_component
69393,GO:0032181,Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.,dinucleotide repeat insertion binding,molecular_function
69394,GO:0032182,Binding to a small conjugating protein such as ubiquitin or a ubiquitin-like protein.,ubiquitin-like protein binding,molecular_function
69395,GO:0032183,Binding to the small ubiquitin-like protein SUMO.,SUMO binding,molecular_function
69396,GO:0032184,Binding to a polymer of the small ubiquitin-like protein SUMO.,SUMO polymer binding,molecular_function
69397,GO:0032185,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.",septin cytoskeleton organization,biological_process
69398,GO:0032186,"Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.",cellular bud neck septin ring organization,biological_process
69399,GO:0032190,"Binding to acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.",acrosin binding,molecular_function
69400,GO:0032195,A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.,post-lysosomal vacuole,cellular_component
69401,GO:0032196,"Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site.",transposition,biological_process
69402,GO:0032197,A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription.,retrotransposition,biological_process
69403,GO:0032200,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.",telomere organization,biological_process
69404,GO:0032201,The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.,telomere maintenance via semi-conservative replication,biological_process
69405,GO:0032202,"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.",telomere assembly,biological_process
69406,GO:0032203,A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.,telomere formation via telomerase,biological_process
69407,GO:0032204,"Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.",regulation of telomere maintenance,biological_process
69408,GO:0032205,"Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.",negative regulation of telomere maintenance,biological_process
69409,GO:0032206,"Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.",positive regulation of telomere maintenance,biological_process
69410,GO:0032207,"Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.",regulation of telomere maintenance via recombination,biological_process
69411,GO:0032208,"Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.",negative regulation of telomere maintenance via recombination,biological_process
69412,GO:0032209,"Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.",positive regulation of telomere maintenance via recombination,biological_process
69413,GO:0032210,"Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.",regulation of telomere maintenance via telomerase,biological_process
69414,GO:0032211,"Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.",negative regulation of telomere maintenance via telomerase,biological_process
69415,GO:0032212,"Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.",positive regulation of telomere maintenance via telomerase,biological_process
69416,GO:0032213,"Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.",regulation of telomere maintenance via semi-conservative replication,biological_process
69417,GO:0032214,"Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.",negative regulation of telomere maintenance via semi-conservative replication,biological_process
69418,GO:0032215,"Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.",positive regulation of telomere maintenance via semi-conservative replication,biological_process
69419,GO:0032216,"Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + fatty acyl-CoA = 2-acyl-6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + CoA.",glucosaminyl-phosphatidylinositol O-acyltransferase activity,molecular_function
69420,GO:0032217,"Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.",riboflavin transmembrane transporter activity,molecular_function
69421,GO:0032218,"The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.",riboflavin transport,biological_process
69422,GO:0032221,"A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).",Rpd3S complex,cellular_component
69423,GO:0032222,"Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.","regulation of synaptic transmission, cholinergic",biological_process
69424,GO:0032223,"Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.","negative regulation of synaptic transmission, cholinergic",biological_process
69425,GO:0032224,"Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.","positive regulation of synaptic transmission, cholinergic",biological_process
69426,GO:0032225,"Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.","regulation of synaptic transmission, dopaminergic",biological_process
69427,GO:0032226,"Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.","positive regulation of synaptic transmission, dopaminergic",biological_process
69428,GO:0032227,"Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.","negative regulation of synaptic transmission, dopaminergic",biological_process
69429,GO:0032228,"Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).","regulation of synaptic transmission, GABAergic",biological_process
69430,GO:0032229,"Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).","negative regulation of synaptic transmission, GABAergic",biological_process
69431,GO:0032230,"Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).","positive regulation of synaptic transmission, GABAergic",biological_process
69432,GO:0032231,"Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.",regulation of actin filament bundle assembly,biological_process
69433,GO:0032232,"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.",negative regulation of actin filament bundle assembly,biological_process
69434,GO:0032233,"Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.",positive regulation of actin filament bundle assembly,biological_process
69435,GO:0032237,A process that initiates the activity of an inactive store-operated calcium channel.,activation of store-operated calcium channel activity,biological_process
69436,GO:0032238,"The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",adenosine transport,biological_process
69437,GO:0032239,"Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of nucleobase-containing compound transport,biological_process
69438,GO:0032240,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of nucleobase-containing compound transport,biological_process
69439,GO:0032241,"Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of nucleobase-containing compound transport,biological_process
69440,GO:0032242,"Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of nucleoside transport,biological_process
69441,GO:0032243,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of nucleoside transport,biological_process
69442,GO:0032244,"Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of nucleoside transport,biological_process
69443,GO:0032245,"Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of purine nucleoside transport,biological_process
69444,GO:0032246,"Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of pyrimidine nucleoside transport,biological_process
69445,GO:0032247,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of purine nucleoside transport,biological_process
69446,GO:0032248,"Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of purine nucleoside transport,biological_process
69447,GO:0032249,"Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of adenosine transport,biological_process
69448,GO:0032250,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of adenosine transport,biological_process
69449,GO:0032251,"Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of adenosine transport,biological_process
69450,GO:0032252,"Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.",secretory granule localization,biological_process
69451,GO:0032253,"Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.",dense core granule localization,biological_process
69452,GO:0032254,The directed movement of a secretory granule to a specific location.,establishment of secretory granule localization,biological_process
69453,GO:0032255,Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of secretory granule location,biological_process
69454,GO:0032256,The directed movement of a dense core granule to a specific location.,establishment of dense core granule localization,biological_process
69455,GO:0032257,Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of dense core granule location,biological_process
69456,GO:0032258,"A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.",cytoplasm to vacuole targeting by the Cvt pathway,biological_process
69457,GO:0032259,The process in which a methyl group is covalently attached to a molecule.,methylation,biological_process
69458,GO:0032260,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.",response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance,biological_process
69459,GO:0032261,"Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.",purine nucleotide salvage,biological_process
69460,GO:0032262,"Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.",pyrimidine nucleotide salvage,biological_process
69461,GO:0032263,"Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.",GMP salvage,biological_process
69462,GO:0032264,"Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.",IMP salvage,biological_process
69463,GO:0032265,"Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.",XMP salvage,biological_process
69464,GO:0032266,"Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.",phosphatidylinositol-3-phosphate binding,molecular_function
69465,GO:0032267,Catalysis of the reaction: ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H+ + lysidine(34) in tRNA(Ile2). This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.,tRNA(Ile)-lysidine synthase activity,molecular_function
69466,GO:0032271,"Any process that modulates the frequency, rate or extent of the process of creating protein polymers.",regulation of protein polymerization,biological_process
69467,GO:0032272,"Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.",negative regulation of protein polymerization,biological_process
69468,GO:0032273,"Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.",positive regulation of protein polymerization,biological_process
69469,GO:0032274,"The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.",gonadotropin secretion,biological_process
69470,GO:0032275,"The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.",luteinizing hormone secretion,biological_process
69471,GO:0032276,"Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.",regulation of gonadotropin secretion,biological_process
69472,GO:0032277,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.",negative regulation of gonadotropin secretion,biological_process
69473,GO:0032278,"Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.",positive regulation of gonadotropin secretion,biological_process
69474,GO:0032279,"A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.",asymmetric synapse,cellular_component
69475,GO:0032280,"A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typically inhibitory.",symmetric synapse,cellular_component
69476,GO:0032281,"An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate ...",AMPA glutamate receptor complex,cellular_component
69477,GO:0032282,An acetyl-CoA carboxylase complex located in the stroma of a plastid.,plastid acetyl-CoA carboxylase complex,cellular_component
69478,GO:0032283,An acetate CoA-transferase complex located in the stroma of a plastid.,plastid acetate CoA-transferase complex,cellular_component
69479,GO:0032285,The process in which a non-myelinating glial cell membrane closes around an axon.,non-myelinated axon ensheathment,biological_process
69480,GO:0032286,The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.,central nervous system myelin maintenance,biological_process
69481,GO:0032287,The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.,peripheral nervous system myelin maintenance,biological_process
69482,GO:0032288,The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.,myelin assembly,biological_process
69483,GO:0032289,The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.,central nervous system myelin formation,biological_process
69484,GO:0032290,The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.,peripheral nervous system myelin formation,biological_process
69485,GO:0032291,The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.,axon ensheathment in central nervous system,biological_process
69486,GO:0032292,The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.,peripheral nervous system axon ensheathment,biological_process
69487,GO:0032293,The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.,non-myelinated axon ensheathment in central nervous system,biological_process
69488,GO:0032294,The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.,peripheral nervous system non-myelinated axon ensheathment,biological_process
69489,GO:0032295,The process in which satellite glial cells isolate neuronal cell bodies.,ensheathment of neuronal cell bodies,biological_process
69490,GO:0032296,Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.,double-stranded RNA-specific ribonuclease activity,molecular_function
69491,GO:0032297,"Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.",negative regulation of DNA-templated DNA replication initiation,biological_process
69492,GO:0032298,"Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.",positive regulation of DNA-templated DNA replication initiation,biological_process
69493,GO:0032299,"A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.",ribonuclease H2 complex,cellular_component
69494,GO:0032300,Any complex formed of proteins that act in mismatch repair.,mismatch repair complex,cellular_component
69495,GO:0032301,"A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.",MutSalpha complex,cellular_component
69496,GO:0032302,"A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.",MutSbeta complex,cellular_component
69497,GO:0032303,"Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.",regulation of icosanoid secretion,biological_process
69498,GO:0032304,"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.",negative regulation of icosanoid secretion,biological_process
69499,GO:0032305,"Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.",positive regulation of icosanoid secretion,biological_process
69500,GO:0032306,"Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.",regulation of prostaglandin secretion,biological_process
69501,GO:0032307,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.",negative regulation of prostaglandin secretion,biological_process
69502,GO:0032308,"Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.",positive regulation of prostaglandin secretion,biological_process
69503,GO:0032309,"The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.",icosanoid secretion,biological_process
69504,GO:0032310,"The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.",prostaglandin secretion,biological_process
69505,GO:0032311,A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.,angiogenin-PRI complex,cellular_component
69506,GO:0032322,"The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.",ubiquinone catabolic process,biological_process
69507,GO:0032323,The chemical reactions and pathways resulting in the breakdown of lipoate.,lipoate catabolic process,biological_process
69508,GO:0032324,"The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.",molybdopterin cofactor biosynthetic process,biological_process
69509,GO:0032325,"The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.",molybdopterin cofactor catabolic process,biological_process
69510,GO:0032326,"The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.",Mo-molybdopterin cofactor catabolic process,biological_process
69511,GO:0032327,"The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.",W-molybdopterin cofactor catabolic process,biological_process
69512,GO:0032328,"The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",alanine transport,biological_process
69513,GO:0032329,"The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",serine transport,biological_process
69514,GO:0032330,"Any process that modulates the frequency, rate or extent of chondrocyte differentiation.",regulation of chondrocyte differentiation,biological_process
69515,GO:0032331,"Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.",negative regulation of chondrocyte differentiation,biological_process
69516,GO:0032332,"Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.",positive regulation of chondrocyte differentiation,biological_process
69517,GO:0032333,"The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.",activin secretion,biological_process
69518,GO:0032334,"The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.",inhibin secretion,biological_process
69519,GO:0032335,"Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.",regulation of activin secretion,biological_process
69520,GO:0032336,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.",negative regulation of activin secretion,biological_process
69521,GO:0032337,"Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.",positive regulation of activin secretion,biological_process
69522,GO:0032338,"Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.",regulation of inhibin secretion,biological_process
69523,GO:0032339,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.",negative regulation of inhibin secretion,biological_process
69524,GO:0032340,"Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.",positive regulation of inhibin secretion,biological_process
69525,GO:0032341,"The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.",aldosterone metabolic process,biological_process
69526,GO:0032342,"The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.",aldosterone biosynthetic process,biological_process
69527,GO:0032343,"The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.",aldosterone catabolic process,biological_process
69528,GO:0032344,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.",regulation of aldosterone metabolic process,biological_process
69529,GO:0032347,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.",regulation of aldosterone biosynthetic process,biological_process
69530,GO:0032348,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.",negative regulation of aldosterone biosynthetic process,biological_process
69531,GO:0032349,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.",positive regulation of aldosterone biosynthetic process,biological_process
69532,GO:0032350,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.",regulation of hormone metabolic process,biological_process
69533,GO:0032351,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.",negative regulation of hormone metabolic process,biological_process
69534,GO:0032352,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.",positive regulation of hormone metabolic process,biological_process
69535,GO:0032353,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.",negative regulation of hormone biosynthetic process,biological_process
69536,GO:0032354,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.",response to follicle-stimulating hormone,biological_process
69537,GO:0032355,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.",response to estradiol,biological_process
69538,GO:0032356,Binding to a DNA region containing an oxidized residue.,oxidized DNA binding,molecular_function
69539,GO:0032357,Binding to a DNA region containing an oxidized purine residue.,oxidized purine DNA binding,molecular_function
69540,GO:0032358,Binding to a DNA region containing an oxidized pyrimidine residue.,oxidized pyrimidine DNA binding,molecular_function
69541,GO:0032359,The molecular events that lead to the excision of a viral genome from the host genome.,provirus excision,biological_process
69542,GO:0032361,"The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.",pyridoxal 5'-phosphate catabolic process,biological_process
69543,GO:0032363,"The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.",FMN catabolic process,biological_process
69544,GO:0032364,A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.,intracellular oxygen homeostasis,biological_process
69545,GO:0032365,The directed movement of lipids within cells.,intracellular lipid transport,biological_process
69546,GO:0032366,The directed movement of sterols within cells.,intracellular sterol transport,biological_process
69547,GO:0032367,"The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.",intracellular cholesterol transport,biological_process
69548,GO:0032368,"Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of lipid transport,biological_process
69549,GO:0032369,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of lipid transport,biological_process
69550,GO:0032370,"Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of lipid transport,biological_process
69551,GO:0032371,"Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of sterol transport,biological_process
69552,GO:0032372,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of sterol transport,biological_process
69553,GO:0032373,"Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of sterol transport,biological_process
69554,GO:0032374,"Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of cholesterol transport,biological_process
69555,GO:0032375,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of cholesterol transport,biological_process
69556,GO:0032376,"Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of cholesterol transport,biological_process
69557,GO:0032377,"Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.",regulation of intracellular lipid transport,biological_process
69558,GO:0032378,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.",negative regulation of intracellular lipid transport,biological_process
69559,GO:0032379,"Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.",positive regulation of intracellular lipid transport,biological_process
69560,GO:0032380,"Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.",regulation of intracellular sterol transport,biological_process
69561,GO:0032381,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.",negative regulation of intracellular sterol transport,biological_process
69562,GO:0032382,"Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.",positive regulation of intracellular sterol transport,biological_process
69563,GO:0032383,"Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.",regulation of intracellular cholesterol transport,biological_process
69564,GO:0032384,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.",negative regulation of intracellular cholesterol transport,biological_process
69565,GO:0032385,"Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.",positive regulation of intracellular cholesterol transport,biological_process
69566,GO:0032386,"Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.",regulation of intracellular transport,biological_process
69567,GO:0032387,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.",negative regulation of intracellular transport,biological_process
69568,GO:0032388,"Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.",positive regulation of intracellular transport,biological_process
69569,GO:0032389,"A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.",MutLalpha complex,cellular_component
69570,GO:0032390,"A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.",MutLbeta complex,cellular_component
69571,GO:0032391,The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.,photoreceptor connecting cilium,cellular_component
69572,GO:0032392,"The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.",DNA geometric change,biological_process
69573,GO:0032393,Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.,MHC class I receptor activity,molecular_function
69574,GO:0032394,"Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.",MHC class Ib receptor activity,molecular_function
69575,GO:0032395,Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,MHC class II receptor activity,molecular_function
69576,GO:0032396,Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.,inhibitory MHC class I receptor activity,molecular_function
69577,GO:0032397,Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.,activating MHC class I receptor activity,molecular_function
69578,GO:0032398,"A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.",MHC class Ib protein complex,cellular_component
69579,GO:0032399,"Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein.",HECT domain binding,molecular_function
69580,GO:0032400,"Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.",melanosome localization,biological_process
69581,GO:0032401,The directed movement of a melanosome to a specific location.,establishment of melanosome localization,biological_process
69582,GO:0032402,"The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",melanosome transport,biological_process
69583,GO:0032404,Binding to a mismatch repair complex.,mismatch repair complex binding,molecular_function
69584,GO:0032405,Binding to a MutLalpha mismatch repair complex.,MutLalpha complex binding,molecular_function
69585,GO:0032406,Binding to a MutLbeta mismatch repair complex.,MutLbeta complex binding,molecular_function
69586,GO:0032407,Binding to a MutSalpha mismatch repair complex.,MutSalpha complex binding,molecular_function
69587,GO:0032408,Binding to a MutSbeta mismatch repair complex.,MutSbeta complex binding,molecular_function
69588,GO:0032410,Any process that stops or reduces the activity of a transporter.,negative regulation of transporter activity,biological_process
69589,GO:0032411,Any process that activates or increases the activity of a transporter.,positive regulation of transporter activity,biological_process
69590,GO:0032413,Any process that stops or reduces the activity of an ion transporter.,negative regulation of ion transmembrane transporter activity,biological_process
69591,GO:0032414,Any process that activates or increases the activity of an ion transporter.,positive regulation of ion transmembrane transporter activity,biological_process
69592,GO:0032417,"Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).",positive regulation of sodium:proton antiporter activity,biological_process
69593,GO:0032418,"Any process in which a lysosome is transported to, and/or maintained in, a specific location.",lysosome localization,biological_process
69594,GO:0032420,"An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.",stereocilium,cellular_component
69595,GO:0032421,"A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.",stereocilium bundle,cellular_component
69596,GO:0032422,"Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.",purine-rich negative regulatory element binding,molecular_function
69597,GO:0032423,"Any process that modulates the frequency, rate or extent of mismatch repair.",regulation of mismatch repair,biological_process
69598,GO:0032424,"Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.",negative regulation of mismatch repair,biological_process
69599,GO:0032425,"Any process that activates or increases the frequency, rate or extent of mismatch repair.",positive regulation of mismatch repair,biological_process
69600,GO:0032426,"A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.",stereocilium tip,cellular_component
69601,GO:0032427,"Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.",GBD domain binding,molecular_function
69602,GO:0032428,Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.,beta-N-acetylgalactosaminidase activity,molecular_function
69603,GO:0032432,An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.,actin filament bundle,cellular_component
69604,GO:0032433,The end of a filopodium distal to the body of the cell.,filopodium tip,cellular_component
69605,GO:0032434,"Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",regulation of proteasomal ubiquitin-dependent protein catabolic process,biological_process
69606,GO:0032435,"Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",negative regulation of proteasomal ubiquitin-dependent protein catabolic process,biological_process
69607,GO:0032436,"Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",positive regulation of proteasomal ubiquitin-dependent protein catabolic process,biological_process
69608,GO:0032437,"A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.",cuticular plate,cellular_component
69609,GO:0032438,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.",melanosome organization,biological_process
69610,GO:0032440,Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.,2-alkenal reductase [NAD(P)H] activity,molecular_function
69611,GO:0032441,Catalysis of the reaction: pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = red chlorophyll catabolite + 2 oxidized [2Fe-2S]-[ferredoxin].,pheophorbide a oxygenase activity,molecular_function
69612,GO:0032442,"Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.",phenylcoumaran benzylic ether reductase activity,molecular_function
69613,GO:0032443,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.",regulation of ergosterol biosynthetic process,biological_process
69614,GO:0032444,"A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.",activin responsive factor complex,cellular_component
69615,GO:0032446,"A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.",protein modification by small protein conjugation,biological_process
69616,GO:0032447,Covalent attachment of the ubiquitin-like protein URM1 to another protein.,protein urmylation,biological_process
69617,GO:0032448,Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.,DNA hairpin binding,molecular_function
69618,GO:0032449,"A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation.",CBM complex,cellular_component
69619,GO:0032451,Catalysis of the removal of a methyl group from a substrate.,demethylase activity,molecular_function
69620,GO:0032452,Catalysis of the removal of a methyl group from a histone.,histone demethylase activity,molecular_function
69621,GO:0032453,Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein.,histone H3K4 demethylase activity,molecular_function
69622,GO:0032454,Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.,histone H3K9 demethylase activity,molecular_function
69623,GO:0032455,The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.,nerve growth factor processing,biological_process
69624,GO:0032456,"The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.",endocytic recycling,biological_process
69625,GO:0032457,The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.,fast endocytic recycling,biological_process
69626,GO:0032458,The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.,slow endocytic recycling,biological_process
69627,GO:0032459,"Any process that modulates the frequency, rate or extent of protein oligomerization.",regulation of protein oligomerization,biological_process
69628,GO:0032460,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.",negative regulation of protein oligomerization,biological_process
69629,GO:0032461,"Any process that activates or increases the frequency, rate or extent of protein oligomerization.",positive regulation of protein oligomerization,biological_process
69630,GO:0032462,"Any process that modulates the frequency, rate or extent of protein homooligomerization.",regulation of protein homooligomerization,biological_process
69631,GO:0032463,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.",negative regulation of protein homooligomerization,biological_process
69632,GO:0032464,"Any process that activates or increases the frequency, rate or extent of protein homooligomerization.",positive regulation of protein homooligomerization,biological_process
69633,GO:0032465,"Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.",regulation of cytokinesis,biological_process
69634,GO:0032466,"Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.",negative regulation of cytokinesis,biological_process
69635,GO:0032467,"Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.",positive regulation of cytokinesis,biological_process
69636,GO:0032468,Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.,Golgi calcium ion homeostasis,biological_process
69637,GO:0032469,Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.,endoplasmic reticulum calcium ion homeostasis,biological_process
69638,GO:0032470,Any process that increases the concentration of calcium ions in the endoplasmic reticulum.,positive regulation of endoplasmic reticulum calcium ion concentration,biological_process
69639,GO:0032471,Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.,negative regulation of endoplasmic reticulum calcium ion concentration,biological_process
69640,GO:0032472,"The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.",Golgi calcium ion transport,biological_process
69641,GO:0032473,"The leaflet of the mitochondrial outer membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of mitochondrial outer membrane,cellular_component
69642,GO:0032474,The process in which the anatomical structures of an otolith are generated and organized.,otolith morphogenesis,biological_process
69643,GO:0032475,The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.,otolith formation,biological_process
69644,GO:0032476,A complex that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms.,polyprenyl diphosphate synthase complex,cellular_component
69645,GO:0032477,A homodimeric complex that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms.,homodimeric polyprenyl diphosphate synthase complex,cellular_component
69646,GO:0032478,A heterotetrameric complex located in the mitochondrial inner membrane that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms. In S. pombe it is a heterotetramer of Dlp1 and Dps1.,heterotetrameric polyprenyl diphosphate synthase complex,cellular_component
69647,GO:0032479,"Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",regulation of type I interferon production,biological_process
69648,GO:0032480,"Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",negative regulation of type I interferon production,biological_process
69649,GO:0032481,"Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",positive regulation of type I interferon production,biological_process
69650,GO:0032482,An intracellular signaling cassette in which a small monomeric GTPase of the Rab subfamily relays a signal.,Rab protein signal transduction,biological_process
69651,GO:0032483,"Any process that modulates the frequency, rate or extent of Rab protein signal transduction.",regulation of Rab protein signal transduction,biological_process
69652,GO:0032484,An intracellular signaling cassette in which a small monomeric GTPase of the RaI subfamily relays a signal.,Ral protein signal transduction,biological_process
69653,GO:0032485,"Any process that modulates the frequency, rate or extent of Ral protein signal transduction.",regulation of Ral protein signal transduction,biological_process
69654,GO:0032486,An intracellular signaling cassette in which a small monomeric GTPase of the Rap subfamily relays a signal.,Rap protein signal transduction,biological_process
69655,GO:0032487,"Any process that modulates the frequency, rate or extent of Rap protein signal transduction.",regulation of Rap protein signal transduction,biological_process
69656,GO:0032488,An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal.,Cdc42 protein signal transduction,biological_process
69657,GO:0032489,"Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.",regulation of Cdc42 protein signal transduction,biological_process
69658,GO:0032490,The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.,detection of molecule of bacterial origin,biological_process
69659,GO:0032491,The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.,detection of molecule of fungal origin,biological_process
69660,GO:0032492,The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.,detection of molecule of oomycetes origin,biological_process
69661,GO:0032493,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.",response to bacterial lipoprotein,biological_process
69662,GO:0032494,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.",response to peptidoglycan,biological_process
69663,GO:0032495,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.",response to muramyl dipeptide,biological_process
69664,GO:0032496,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.",response to lipopolysaccharide,biological_process
69665,GO:0032497,The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.,detection of lipopolysaccharide,biological_process
69666,GO:0032498,The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.,detection of muramyl dipeptide,biological_process
69667,GO:0032499,The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.,detection of peptidoglycan,biological_process
69668,GO:0032500,"Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.",muramyl dipeptide binding,molecular_function
69669,GO:0032501,"Any biological process, occurring at the level of a multicellular organism, pertinent to its function.",multicellular organismal process,biological_process
69670,GO:0032502,"A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.",developmental process,biological_process
69671,GO:0032506,A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).,cytokinetic process,biological_process
69672,GO:0032507,"Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.",maintenance of protein location in cell,biological_process
69673,GO:0032509,"The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.",endosome transport via multivesicular body sorting pathway,biological_process
69674,GO:0032510,"The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.",endosome to lysosome transport via multivesicular body sorting pathway,biological_process
69675,GO:0032511,"The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.",late endosome to vacuole transport via multivesicular body sorting pathway,biological_process
69676,GO:0032517,A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.,SOD1-calcineurin complex,cellular_component
69677,GO:0032523,Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.,silicon efflux transmembrane transporter activity,molecular_function
69678,GO:0032525,"The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.",somite rostral/caudal axis specification,biological_process
69679,GO:0032526,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.",response to retinoic acid,biological_process
69680,GO:0032528,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.",microvillus organization,biological_process
69681,GO:0032529,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.",follicle cell microvillus organization,biological_process
69682,GO:0032530,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.",regulation of microvillus organization,biological_process
69683,GO:0032531,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.",regulation of follicle cell microvillus organization,biological_process
69684,GO:0032532,A process that modulates the length of a microvillus.,regulation of microvillus length,biological_process
69685,GO:0032533,A process that modulates the length of a microvillus on a follicle cell.,regulation of follicle cell microvillus length,biological_process
69686,GO:0032534,A process that modulates the formation of a microvillus.,regulation of microvillus assembly,biological_process
69687,GO:0032535,A process that modulates the size of a cellular component.,regulation of cellular component size,biological_process
69688,GO:0032536,A process that modulates the size of a cell projection.,regulation of cell projection size,biological_process
69689,GO:0032537,"The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.",host-seeking behavior,biological_process
69690,GO:0032538,"Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.",regulation of host-seeking behavior,biological_process
69691,GO:0032539,"Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.",negative regulation of host-seeking behavior,biological_process
69692,GO:0032540,"Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.",positive regulation of host-seeking behavior,biological_process
69693,GO:0032541,A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.,cortical endoplasmic reticulum,cellular_component
69694,GO:0032542,Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.,sulfiredoxin activity,molecular_function
69695,GO:0032543,"The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.",mitochondrial translation,biological_process
69696,GO:0032544,"The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.",plastid translation,biological_process
69697,GO:0032545,"A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.",CURI complex,cellular_component
69698,GO:0032546,"Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.",deoxyribonucleoside binding,molecular_function
69699,GO:0032547,"Binding to a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.",purine deoxyribonucleoside binding,molecular_function
69700,GO:0032548,"Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.",pyrimidine deoxyribonucleoside binding,molecular_function
69701,GO:0032549,"Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.",ribonucleoside binding,molecular_function
69702,GO:0032550,"Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.",purine ribonucleoside binding,molecular_function
69703,GO:0032551,"Binding to a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.",pyrimidine ribonucleoside binding,molecular_function
69704,GO:0032552,"Binding to a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.",deoxyribonucleotide binding,molecular_function
69705,GO:0032553,"Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.",ribonucleotide binding,molecular_function
69706,GO:0032554,"Binding to a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.",purine deoxyribonucleotide binding,molecular_function
69707,GO:0032555,"Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.",purine ribonucleotide binding,molecular_function
69708,GO:0032556,"Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.",pyrimidine deoxyribonucleotide binding,molecular_function
69709,GO:0032557,"Binding to a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.",pyrimidine ribonucleotide binding,molecular_function
69710,GO:0032558,"Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.",adenyl deoxyribonucleotide binding,molecular_function
69711,GO:0032559,"Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.",adenyl ribonucleotide binding,molecular_function
69712,GO:0032560,"Binding to a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.",guanyl deoxyribonucleotide binding,molecular_function
69713,GO:0032561,"Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.",guanyl ribonucleotide binding,molecular_function
69714,GO:0032562,"Binding to dAMP, deoxyadenosine monophosphate.",dAMP binding,molecular_function
69715,GO:0032563,"Binding to dADP, deoxyadenosine diphosphate.",dADP binding,molecular_function
69716,GO:0032564,"Binding to dATP, deoxyadenosine triphosphate.",dATP binding,molecular_function
69717,GO:0032565,"Binding to dGMP, deoxyguanosine monophosphate.",dGMP binding,molecular_function
69718,GO:0032566,"Binding to dGDP, deoxyguanosine diphosphate.",dGDP binding,molecular_function
69719,GO:0032567,"Binding to dGTP, deoxyguanosine triphosphate.",dGTP binding,molecular_function
69720,GO:0032570,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.",response to progesterone,biological_process
69721,GO:0032571,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.",response to vitamin K,biological_process
69722,GO:0032572,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.",response to menaquinone,biological_process
69723,GO:0032573,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.",response to phylloquinone,biological_process
69724,GO:0032574,"Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.",5'-3' RNA helicase activity,molecular_function
69725,GO:0032576,"Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.",O-linoleoyltransferase activity,molecular_function
69726,GO:0032577,"Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.",phosphatidylcholine:cardiolipin O-linoleoyltransferase activity,molecular_function
69727,GO:0032578,The lipid bilayer surrounding an aleurone grain.,aleurone grain membrane,cellular_component
69728,GO:0032579,A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.,apical lamina of hyaline layer,cellular_component
69729,GO:0032580,"The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.",Golgi cisterna membrane,cellular_component
69730,GO:0032581,A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.,ER-dependent peroxisome organization,biological_process
69731,GO:0032584,The portion of the plasma membrane surrounding a growth cone.,growth cone membrane,cellular_component
69732,GO:0032585,The lipid bilayer surrounding a multivesicular body.,multivesicular body membrane,cellular_component
69733,GO:0032586,The lipid bilayer surrounding a protein storage vacuole.,protein storage vacuole membrane,cellular_component
69734,GO:0032587,The portion of the plasma membrane surrounding a ruffle.,ruffle membrane,cellular_component
69735,GO:0032588,The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.,trans-Golgi network membrane,cellular_component
69736,GO:0032589,The portion of the plasma membrane surrounding a neuron projection.,neuron projection membrane,cellular_component
69737,GO:0032590,The portion of the plasma membrane surrounding a dendrite.,dendrite membrane,cellular_component
69738,GO:0032591,The portion of the plasma membrane surrounding a dendritic spine.,dendritic spine membrane,cellular_component
69739,GO:0032593,"A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.",insulin-responsive compartment,cellular_component
69740,GO:0032594,The directed movement of a protein from one location to another within a lipid bilayer.,protein transport within lipid bilayer,biological_process
69741,GO:0032595,The directed movement of a B cell receptor within a lipid bilayer.,B cell receptor transport within lipid bilayer,biological_process
69742,GO:0032596,"The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.",protein transport into membrane raft,biological_process
69743,GO:0032597,The directed movement of a B cell receptor into a membrane raft.,B cell receptor transport into membrane raft,biological_process
69744,GO:0032598,The directed movement of a B cell receptor into an immunological synapse.,B cell receptor transport into immunological synapse,biological_process
69745,GO:0032599,"The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.",protein transport out of membrane raft,biological_process
69746,GO:0032600,The directed movement of a chemokine receptor out of a membrane raft.,chemokine receptor transport out of membrane raft,biological_process
69747,GO:0032601,"The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",connective tissue growth factor production,biological_process
69748,GO:0032602,"The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in c...",chemokine production,biological_process
69749,GO:0032603,"The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",fractalkine production,biological_process
69750,GO:0032604,"The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",granulocyte macrophage colony-stimulating factor production,biological_process
69751,GO:0032605,"The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",hepatocyte growth factor production,biological_process
69752,GO:0032606,"The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",type I interferon production,biological_process
69753,GO:0032607,"The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-alpha production,biological_process
69754,GO:0032608,"The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-beta production,biological_process
69755,GO:0032609,"The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.",type II interferon production,biological_process
69756,GO:0032610,"The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-1 alpha production,biological_process
69757,GO:0032611,"The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-1 beta production,biological_process
69758,GO:0032612,"The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-1 production,biological_process
69759,GO:0032613,"The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-10 production,biological_process
69760,GO:0032614,"The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-11 production,biological_process
69761,GO:0032615,"The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-12 production,biological_process
69762,GO:0032616,"The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-13 production,biological_process
69763,GO:0032618,"The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-15 production,biological_process
69764,GO:0032619,"The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-16 production,biological_process
69765,GO:0032620,"The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-17 production,biological_process
69766,GO:0032621,"The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-18 production,biological_process
69767,GO:0032622,"The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-19 production,biological_process
69768,GO:0032623,"The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-2 production,biological_process
69769,GO:0032624,"The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-20 production,biological_process
69770,GO:0032625,"The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-21 production,biological_process
69771,GO:0032626,"The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-22 production,biological_process
69772,GO:0032627,"The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-23 production,biological_process
69773,GO:0032628,"The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-24 production,biological_process
69774,GO:0032629,"The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-25 production,biological_process
69775,GO:0032630,"The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-26 production,biological_process
69776,GO:0032631,"The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-27 production,biological_process
69777,GO:0032632,"The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-3 production,biological_process
69778,GO:0032633,"The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-4 production,biological_process
69779,GO:0032634,"The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-5 production,biological_process
69780,GO:0032635,"The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-6 production,biological_process
69781,GO:0032636,"The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-7 production,biological_process
69782,GO:0032637,"The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-8 production,biological_process
69783,GO:0032638,"The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-9 production,biological_process
69784,GO:0032639,"The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",TRAIL production,biological_process
69785,GO:0032640,"The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.",tumor necrosis factor production,biological_process
69786,GO:0032641,The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.,lymphotoxin A production,biological_process
69787,GO:0032642,"Any process that modulates the frequency, rate, or extent of chemokine production.",regulation of chemokine production,biological_process
69788,GO:0032643,"Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.",regulation of connective tissue growth factor production,biological_process
69789,GO:0032644,"Any process that modulates the frequency, rate, or extent of fractalkine production.",regulation of fractalkine production,biological_process
69790,GO:0032645,"Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.",regulation of granulocyte macrophage colony-stimulating factor production,biological_process
69791,GO:0032646,"Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production.",regulation of hepatocyte growth factor production,biological_process
69792,GO:0032647,"Any process that modulates the frequency, rate, or extent of interferon-alpha production.",regulation of interferon-alpha production,biological_process
69793,GO:0032648,"Any process that modulates the frequency, rate, or extent of interferon-beta production.",regulation of interferon-beta production,biological_process
69794,GO:0032649,"Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.",regulation of type II interferon production,biological_process
69795,GO:0032650,"Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production.",regulation of interleukin-1 alpha production,biological_process
69796,GO:0032651,"Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.",regulation of interleukin-1 beta production,biological_process
69797,GO:0032652,"Any process that modulates the frequency, rate, or extent of interleukin-1 production.",regulation of interleukin-1 production,biological_process
69798,GO:0032653,"Any process that modulates the frequency, rate, or extent of interleukin-10 production.",regulation of interleukin-10 production,biological_process
69799,GO:0032654,"Any process that modulates the frequency, rate, or extent of interleukin-11 production.",regulation of interleukin-11 production,biological_process
69800,GO:0032655,"Any process that modulates the frequency, rate, or extent of interleukin-12 production.",regulation of interleukin-12 production,biological_process
69801,GO:0032656,"Any process that modulates the frequency, rate, or extent of interleukin-13 production.",regulation of interleukin-13 production,biological_process
69802,GO:0032658,"Any process that modulates the frequency, rate, or extent of interleukin-15 production.",regulation of interleukin-15 production,biological_process
69803,GO:0032659,"Any process that modulates the frequency, rate, or extent of interleukin-16 production.",regulation of interleukin-16 production,biological_process
69804,GO:0032660,"Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.",regulation of interleukin-17 production,biological_process
69805,GO:0032661,"Any process that modulates the frequency, rate, or extent of interleukin-18 production.",regulation of interleukin-18 production,biological_process
69806,GO:0032662,"Any process that modulates the frequency, rate, or extent of interleukin-19 production.",regulation of interleukin-19 production,biological_process
69807,GO:0032663,"Any process that modulates the frequency, rate, or extent of interleukin-2 production.",regulation of interleukin-2 production,biological_process
69808,GO:0032664,"Any process that modulates the frequency, rate, or extent of interleukin-20 production.",regulation of interleukin-20 production,biological_process
69809,GO:0032665,"Any process that modulates the frequency, rate, or extent of interleukin-21 production.",regulation of interleukin-21 production,biological_process
69810,GO:0032666,"Any process that modulates the frequency, rate, or extent of interleukin-22 production.",regulation of interleukin-22 production,biological_process
69811,GO:0032667,"Any process that modulates the frequency, rate, or extent of interleukin-23 production.",regulation of interleukin-23 production,biological_process
69812,GO:0032668,"Any process that modulates the frequency, rate, or extent of interleukin-24 production.",regulation of interleukin-24 production,biological_process
69813,GO:0032669,"Any process that modulates the frequency, rate, or extent of interleukin-25 production.",regulation of interleukin-25 production,biological_process
69814,GO:0032670,"Any process that modulates the frequency, rate, or extent of interleukin-26 production.",regulation of interleukin-26 production,biological_process
69815,GO:0032671,"Any process that modulates the frequency, rate, or extent of interleukin-27 production.",regulation of interleukin-27 production,biological_process
69816,GO:0032672,"Any process that modulates the frequency, rate, or extent of interleukin-3 production.",regulation of interleukin-3 production,biological_process
69817,GO:0032673,"Any process that modulates the frequency, rate, or extent of interleukin-4 production.",regulation of interleukin-4 production,biological_process
69818,GO:0032674,"Any process that modulates the frequency, rate, or extent of interleukin-5 production.",regulation of interleukin-5 production,biological_process
69819,GO:0032675,"Any process that modulates the frequency, rate, or extent of interleukin-6 production.",regulation of interleukin-6 production,biological_process
69820,GO:0032676,"Any process that modulates the frequency, rate, or extent of interleukin-7 production.",regulation of interleukin-7 production,biological_process
69821,GO:0032677,"Any process that modulates the frequency, rate, or extent of interleukin-8 production.",regulation of interleukin-8 production,biological_process
69822,GO:0032678,"Any process that modulates the frequency, rate, or extent of interleukin-9 production.",regulation of interleukin-9 production,biological_process
69823,GO:0032679,"Any process that modulates the frequency, rate, or extent of TRAIL production.",regulation of TRAIL production,biological_process
69824,GO:0032680,"Any process that modulates the frequency, rate or extent of tumor necrosis factor production.",regulation of tumor necrosis factor production,biological_process
69825,GO:0032681,"Any process that modulates the frequency, rate, or extent of lymphotoxin A production.",regulation of lymphotoxin A production,biological_process
69826,GO:0032682,"Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.",negative regulation of chemokine production,biological_process
69827,GO:0032683,"Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.",negative regulation of connective tissue growth factor production,biological_process
69828,GO:0032684,"Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.",negative regulation of fractalkine production,biological_process
69829,GO:0032685,"Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.",negative regulation of granulocyte macrophage colony-stimulating factor production,biological_process
69830,GO:0032686,"Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.",negative regulation of hepatocyte growth factor production,biological_process
69831,GO:0032687,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.",negative regulation of interferon-alpha production,biological_process
69832,GO:0032688,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.",negative regulation of interferon-beta production,biological_process
69833,GO:0032689,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.",negative regulation of type II interferon production,biological_process
69834,GO:0032690,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.",negative regulation of interleukin-1 alpha production,biological_process
69835,GO:0032691,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.",negative regulation of interleukin-1 beta production,biological_process
69836,GO:0032692,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.",negative regulation of interleukin-1 production,biological_process
69837,GO:0032693,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.",negative regulation of interleukin-10 production,biological_process
69838,GO:0032694,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.",negative regulation of interleukin-11 production,biological_process
69839,GO:0032695,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.",negative regulation of interleukin-12 production,biological_process
69840,GO:0032696,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.",negative regulation of interleukin-13 production,biological_process
69841,GO:0032698,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.",negative regulation of interleukin-15 production,biological_process
69842,GO:0032699,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.",negative regulation of interleukin-16 production,biological_process
69843,GO:0032700,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.",negative regulation of interleukin-17 production,biological_process
69844,GO:0032701,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.",negative regulation of interleukin-18 production,biological_process
69845,GO:0032702,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.",negative regulation of interleukin-19 production,biological_process
69846,GO:0032703,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.",negative regulation of interleukin-2 production,biological_process
69847,GO:0032704,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.",negative regulation of interleukin-20 production,biological_process
69848,GO:0032705,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.",negative regulation of interleukin-21 production,biological_process
69849,GO:0032706,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.",negative regulation of interleukin-22 production,biological_process
69850,GO:0032707,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.",negative regulation of interleukin-23 production,biological_process
69851,GO:0032708,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.",negative regulation of interleukin-24 production,biological_process
69852,GO:0032709,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.",negative regulation of interleukin-25 production,biological_process
69853,GO:0032710,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.",negative regulation of interleukin-26 production,biological_process
69854,GO:0032711,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.",negative regulation of interleukin-27 production,biological_process
69855,GO:0032712,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.",negative regulation of interleukin-3 production,biological_process
69856,GO:0032713,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.",negative regulation of interleukin-4 production,biological_process
69857,GO:0032714,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.",negative regulation of interleukin-5 production,biological_process
69858,GO:0032715,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.",negative regulation of interleukin-6 production,biological_process
69859,GO:0032716,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.",negative regulation of interleukin-7 production,biological_process
69860,GO:0032717,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.",negative regulation of interleukin-8 production,biological_process
69861,GO:0032718,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.",negative regulation of interleukin-9 production,biological_process
69862,GO:0032719,"Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production.",negative regulation of TRAIL production,biological_process
69863,GO:0032720,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.",negative regulation of tumor necrosis factor production,biological_process
69864,GO:0032721,"Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.",negative regulation of lymphotoxin A production,biological_process
69865,GO:0032722,"Any process that activates or increases the frequency, rate, or extent of chemokine production.",positive regulation of chemokine production,biological_process
69866,GO:0032723,"Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.",positive regulation of connective tissue growth factor production,biological_process
69867,GO:0032724,"Any process that activates or increases the frequency, rate, or extent of fractalkine production.",positive regulation of fractalkine production,biological_process
69868,GO:0032725,"Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.",positive regulation of granulocyte macrophage colony-stimulating factor production,biological_process
69869,GO:0032726,"Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.",positive regulation of hepatocyte growth factor production,biological_process
69870,GO:0032727,"Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.",positive regulation of interferon-alpha production,biological_process
69871,GO:0032728,"Any process that activates or increases the frequency, rate, or extent of interferon-beta production.",positive regulation of interferon-beta production,biological_process
69872,GO:0032729,"Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.",positive regulation of type II interferon production,biological_process
69873,GO:0032730,"Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.",positive regulation of interleukin-1 alpha production,biological_process
69874,GO:0032731,"Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.",positive regulation of interleukin-1 beta production,biological_process
69875,GO:0032732,"Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.",positive regulation of interleukin-1 production,biological_process
69876,GO:0032733,"Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.",positive regulation of interleukin-10 production,biological_process
69877,GO:0032734,"Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.",positive regulation of interleukin-11 production,biological_process
69878,GO:0032735,"Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.",positive regulation of interleukin-12 production,biological_process
69879,GO:0032736,"Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.",positive regulation of interleukin-13 production,biological_process
69880,GO:0032738,"Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.",positive regulation of interleukin-15 production,biological_process
69881,GO:0032739,"Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.",positive regulation of interleukin-16 production,biological_process
69882,GO:0032740,"Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.",positive regulation of interleukin-17 production,biological_process
69883,GO:0032741,"Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.",positive regulation of interleukin-18 production,biological_process
69884,GO:0032742,"Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.",positive regulation of interleukin-19 production,biological_process
69885,GO:0032743,"Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.",positive regulation of interleukin-2 production,biological_process
69886,GO:0032744,"Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.",positive regulation of interleukin-20 production,biological_process
69887,GO:0032745,"Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.",positive regulation of interleukin-21 production,biological_process
69888,GO:0032746,"Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.",positive regulation of interleukin-22 production,biological_process
69889,GO:0032747,"Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.",positive regulation of interleukin-23 production,biological_process
69890,GO:0032748,"Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.",positive regulation of interleukin-24 production,biological_process
69891,GO:0032749,"Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.",positive regulation of interleukin-25 production,biological_process
69892,GO:0032750,"Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.",positive regulation of interleukin-26 production,biological_process
69893,GO:0032751,"Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.",positive regulation of interleukin-27 production,biological_process
69894,GO:0032752,"Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.",positive regulation of interleukin-3 production,biological_process
69895,GO:0032753,"Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.",positive regulation of interleukin-4 production,biological_process
69896,GO:0032754,"Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.",positive regulation of interleukin-5 production,biological_process
69897,GO:0032755,"Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.",positive regulation of interleukin-6 production,biological_process
69898,GO:0032756,"Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.",positive regulation of interleukin-7 production,biological_process
69899,GO:0032757,"Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.",positive regulation of interleukin-8 production,biological_process
69900,GO:0032758,"Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.",positive regulation of interleukin-9 production,biological_process
69901,GO:0032759,"Any process that activates or increases the frequency, rate, or extent of TRAIL production.",positive regulation of TRAIL production,biological_process
69902,GO:0032760,"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production.",positive regulation of tumor necrosis factor production,biological_process
69903,GO:0032761,"Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.",positive regulation of lymphotoxin A production,biological_process
69904,GO:0032762,Any process that contributes to cytokine production by a mast cell.,mast cell cytokine production,biological_process
69905,GO:0032763,"Any process that modulates the frequency, rate, or extent of mast cell cytokine production.",regulation of mast cell cytokine production,biological_process
69906,GO:0032764,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.",negative regulation of mast cell cytokine production,biological_process
69907,GO:0032765,"Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.",positive regulation of mast cell cytokine production,biological_process
69908,GO:0032766,"A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.",NHE3/E3KARP/ACTN4 complex,cellular_component
69909,GO:0032767,"Binding to a protein or protein complex, in the presence of copper.",copper-dependent protein binding,molecular_function
69910,GO:0032774,"The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.",RNA biosynthetic process,biological_process
69911,GO:0032777,"A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.",piccolo histone acetyltransferase complex,cellular_component
69912,GO:0032778,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Co2+(out) = ADP + phosphate + Co2+(in).,P-type cobalt transporter activity,molecular_function
69913,GO:0032780,Any process that stops or reduces the rate of an ATP-dependent activity.,negative regulation of ATP-dependent activity,biological_process
69914,GO:0032781,Any process that activates or increases the rate of an ATP-dependent activity.,positive regulation of ATP-dependent activity,biological_process
69915,GO:0032782,"The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.",bile acid secretion,biological_process
69916,GO:0032783,"A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.",super elongation complex,cellular_component
69917,GO:0032784,"Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.",regulation of DNA-templated transcription elongation,biological_process
69918,GO:0032785,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.","negative regulation of DNA-templated transcription, elongation",biological_process
69919,GO:0032786,"Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.","positive regulation of DNA-templated transcription, elongation",biological_process
69920,GO:0032787,"The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).",monocarboxylic acid metabolic process,biological_process
69921,GO:0032788,"The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.",saturated monocarboxylic acid metabolic process,biological_process
69922,GO:0032789,"The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.",unsaturated monocarboxylic acid metabolic process,biological_process
69923,GO:0032790,The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.,ribosome disassembly,biological_process
69924,GO:0032791,Binding to lead (Pb) ions.,lead ion binding,molecular_function
69925,GO:0032794,Binding to a GTPase activating protein.,GTPase activating protein binding,molecular_function
69926,GO:0032795,Binding to a heterotrimeric G-protein.,heterotrimeric G-protein binding,molecular_function
69927,GO:0032796,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.",uropod organization,biological_process
69928,GO:0032797,"A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.",SMN complex,cellular_component
69929,GO:0032798,"A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).",Swi5-Sfr1 complex,cellular_component
69930,GO:0032799,The chemical reactions and pathways involving low-density lipoprotein receptors.,low-density lipoprotein receptor particle metabolic process,biological_process
69931,GO:0032801,"The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.",receptor catabolic process,biological_process
69932,GO:0032802,"The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.",low-density lipoprotein particle receptor catabolic process,biological_process
69933,GO:0032803,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.",regulation of low-density lipoprotein particle receptor catabolic process,biological_process
69934,GO:0032804,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.",negative regulation of low-density lipoprotein particle receptor catabolic process,biological_process
69935,GO:0032805,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.",positive regulation of low-density lipoprotein particle receptor catabolic process,biological_process
69936,GO:0032806,A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.,carboxy-terminal domain protein kinase complex,cellular_component
69937,GO:0032807,"A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.",DNA ligase IV complex,cellular_component
69938,GO:0032808,"The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.",lacrimal gland development,biological_process
69939,GO:0032809,The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.,neuronal cell body membrane,cellular_component
69940,GO:0032810,"Binding to a sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.",sterol response element binding,molecular_function
69941,GO:0032811,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.",negative regulation of epinephrine secretion,biological_process
69942,GO:0032812,"Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.",positive regulation of epinephrine secretion,biological_process
69943,GO:0032813,Binding to a member of the tumor necrosis factor receptor superfamily.,tumor necrosis factor receptor superfamily binding,molecular_function
69944,GO:0032814,"Any process that modulates the frequency, rate or extent of natural killer cell activation.",regulation of natural killer cell activation,biological_process
69945,GO:0032815,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.",negative regulation of natural killer cell activation,biological_process
69946,GO:0032816,"Any process that activates or increases the frequency, rate or extent of natural killer cell activation.",positive regulation of natural killer cell activation,biological_process
69947,GO:0032817,"Any process that modulates the frequency, rate or extent of natural killer cell proliferation.",regulation of natural killer cell proliferation,biological_process
69948,GO:0032818,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.",negative regulation of natural killer cell proliferation,biological_process
69949,GO:0032819,"Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.",positive regulation of natural killer cell proliferation,biological_process
69950,GO:0032823,"Any process that modulates the frequency, rate or extent of natural killer cell differentiation.",regulation of natural killer cell differentiation,biological_process
69951,GO:0032824,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.",negative regulation of natural killer cell differentiation,biological_process
69952,GO:0032825,"Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.",positive regulation of natural killer cell differentiation,biological_process
69953,GO:0032829,"Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.","regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation",biological_process
69954,GO:0032830,"Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.","negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation",biological_process
69955,GO:0032831,"Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.","positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation",biological_process
69956,GO:0032835,The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.,glomerulus development,biological_process
69957,GO:0032836,"The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.",glomerular basement membrane development,biological_process
69958,GO:0032837,"The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila me...",distributive segregation,biological_process
69959,GO:0032838,"All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.",plasma membrane bounded cell projection cytoplasm,cellular_component
69960,GO:0032839,"All of the contents of a dendrite, excluding the surrounding plasma membrane.",dendrite cytoplasm,cellular_component
69961,GO:0032841,"Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.",calcitonin binding,molecular_function
69962,GO:0032865,A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.,ERMES complex,cellular_component
69963,GO:0032866,Catalysis of the reaction: xylitol + NADP+ = D-xylose + NADPH + H+.,D-xylose reductase (NADPH) activity,molecular_function
69964,GO:0032867,Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+.,L-arabinose reductase (NADPH) activity,molecular_function
69965,GO:0032868,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.",response to insulin,biological_process
69966,GO:0032869,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.",cellular response to insulin stimulus,biological_process
69967,GO:0032870,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.",cellular response to hormone stimulus,biological_process
69968,GO:0032871,"Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.",regulation of karyogamy,biological_process
69969,GO:0032872,"Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.",regulation of stress-activated MAPK cascade,biological_process
69970,GO:0032873,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.",negative regulation of stress-activated MAPK cascade,biological_process
69971,GO:0032874,"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.",positive regulation of stress-activated MAPK cascade,biological_process
69972,GO:0032875,"Any process that modulates the frequency, rate or extent of DNA endoreduplication.",regulation of DNA endoreduplication,biological_process
69973,GO:0032876,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.",negative regulation of DNA endoreduplication,biological_process
69974,GO:0032877,"Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.",positive regulation of DNA endoreduplication,biological_process
69975,GO:0032878,"Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.",regulation of establishment or maintenance of cell polarity,biological_process
69976,GO:0032879,"Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.",regulation of localization,biological_process
69977,GO:0032880,"Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.",regulation of protein localization,biological_process
69978,GO:0032881,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.",regulation of polysaccharide metabolic process,biological_process
69979,GO:0032882,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.",regulation of chitin metabolic process,biological_process
69980,GO:0032883,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.",regulation of chitin biosynthetic process,biological_process
69981,GO:0032885,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.",regulation of polysaccharide biosynthetic process,biological_process
69982,GO:0032886,"Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.",regulation of microtubule-based process,biological_process
69983,GO:0032887,"Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.",regulation of spindle elongation,biological_process
69984,GO:0032888,"Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.",regulation of mitotic spindle elongation,biological_process
69985,GO:0032889,"Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.","regulation of vacuole fusion, non-autophagic",biological_process
69986,GO:0032890,"Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of organic acid transport,biological_process
69987,GO:0032891,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of organic acid transport,biological_process
69988,GO:0032892,"Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of organic acid transport,biological_process
69989,GO:0032896,Catalysis of the reaction: hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.,palmitoyl-CoA 9-desaturase activity,molecular_function
69990,GO:0032897,"Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.",negative regulation of viral transcription,biological_process
69991,GO:0032898,"The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.",neurotrophin production,biological_process
69992,GO:0032899,"Any process that modulates the frequency, rate, or extent of production of a neurotrophin.",regulation of neurotrophin production,biological_process
69993,GO:0032900,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.",negative regulation of neurotrophin production,biological_process
69994,GO:0032901,"Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.",positive regulation of neurotrophin production,biological_process
69995,GO:0032902,"The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.",nerve growth factor production,biological_process
69996,GO:0032903,"Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).",regulation of nerve growth factor production,biological_process
69997,GO:0032904,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).",negative regulation of nerve growth factor production,biological_process
69998,GO:0032905,"The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",transforming growth factor beta1 production,biological_process
69999,GO:0032906,"The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",transforming growth factor beta2 production,biological_process
70000,GO:0032907,"The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",transforming growth factor beta3 production,biological_process
70001,GO:0032908,"Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.",regulation of transforming growth factor beta1 production,biological_process
70002,GO:0032909,"Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.",regulation of transforming growth factor beta2 production,biological_process
70003,GO:0032910,"Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.",regulation of transforming growth factor beta3 production,biological_process
70004,GO:0032911,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.",negative regulation of transforming growth factor beta1 production,biological_process
70005,GO:0032912,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.",negative regulation of transforming growth factor beta2 production,biological_process
70006,GO:0032913,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.",negative regulation of transforming growth factor beta3 production,biological_process
70007,GO:0032914,"Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.",positive regulation of transforming growth factor beta1 production,biological_process
70008,GO:0032915,"Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.",positive regulation of transforming growth factor beta2 production,biological_process
70009,GO:0032916,"Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.",positive regulation of transforming growth factor beta3 production,biological_process
70010,GO:0032921,"A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.",sarcosine oxidase complex,cellular_component
70011,GO:0032922,"Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.",circadian regulation of gene expression,biological_process
70012,GO:0032923,"The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.",organic phosphonate biosynthetic process,biological_process
70013,GO:0032924,"The series of molecular signals initiated by an extracellular ligand binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",activin receptor signaling pathway,biological_process
70014,GO:0032925,"Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.",regulation of activin receptor signaling pathway,biological_process
70015,GO:0032926,"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.",negative regulation of activin receptor signaling pathway,biological_process
70016,GO:0032927,"Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.",positive regulation of activin receptor signaling pathway,biological_process
70017,GO:0032928,"Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.",regulation of superoxide anion generation,biological_process
70018,GO:0032929,"Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.",negative regulation of superoxide anion generation,biological_process
70019,GO:0032930,"Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.",positive regulation of superoxide anion generation,biological_process
70020,GO:0032931,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).,histone H3K56 acetyltransferase activity,molecular_function
70021,GO:0032932,"Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.",negative regulation of astral microtubule depolymerization,biological_process
70022,GO:0032933,"The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.",SREBP signaling pathway,biological_process
70023,GO:0032934,"Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.",sterol binding,molecular_function
70024,GO:0032935,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of a sterol.",sterol sensor activity,molecular_function
70025,GO:0032936,"A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.",SREBP-SCAP complex,cellular_component
70026,GO:0032937,"A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.",SREBP-SCAP-Insig complex,cellular_component
70027,GO:0032938,"Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.",negative regulation of translation in response to oxidative stress,biological_process
70028,GO:0032939,"Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.",positive regulation of translation in response to oxidative stress,biological_process
70029,GO:0032940,The controlled release of a substance by a cell.,secretion by cell,biological_process
70030,GO:0032941,The controlled release of a substance by a tissue.,secretion by tissue,biological_process
70031,GO:0032942,"Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + ADP + H+.","inositol-1,4,5,6-tetrakisphosphate 2-kinase activity",molecular_function
70032,GO:0032943,The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.,mononuclear cell proliferation,biological_process
70033,GO:0032944,"Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.",regulation of mononuclear cell proliferation,biological_process
70034,GO:0032945,"Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.",negative regulation of mononuclear cell proliferation,biological_process
70035,GO:0032946,"Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.",positive regulation of mononuclear cell proliferation,biological_process
70036,GO:0032948,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.",regulation of alpha-glucan metabolic process,biological_process
70037,GO:0032949,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.",regulation of alpha-glucan biosynthetic process,biological_process
70038,GO:0032950,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.",regulation of beta-glucan metabolic process,biological_process
70039,GO:0032951,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.",regulation of beta-glucan biosynthetic process,biological_process
70040,GO:0032953,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.",regulation of (1->3)-beta-D-glucan biosynthetic process,biological_process
70041,GO:0032954,"Any process that modulates the frequency, rate or extent of a cytokinetic process.",regulation of cytokinetic process,biological_process
70042,GO:0032955,"Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",regulation of division septum assembly,biological_process
70043,GO:0032956,"Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.",regulation of actin cytoskeleton organization,biological_process
70044,GO:0032957,"The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.",inositol trisphosphate metabolic process,biological_process
70045,GO:0032958,"The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",inositol phosphate biosynthetic process,biological_process
70046,GO:0032959,"The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.",inositol trisphosphate biosynthetic process,biological_process
70047,GO:0032960,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.",regulation of inositol trisphosphate biosynthetic process,biological_process
70048,GO:0032961,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.",negative regulation of inositol trisphosphate biosynthetic process,biological_process
70049,GO:0032962,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.",positive regulation of inositol trisphosphate biosynthetic process,biological_process
70050,GO:0032963,"The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).",collagen metabolic process,biological_process
70051,GO:0032964,"The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).",collagen biosynthetic process,biological_process
70052,GO:0032965,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",regulation of collagen biosynthetic process,biological_process
70053,GO:0032966,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",negative regulation of collagen biosynthetic process,biological_process
70054,GO:0032967,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.",positive regulation of collagen biosynthetic process,biological_process
70055,GO:0032968,"Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.",positive regulation of transcription elongation by RNA polymerase II,biological_process
70056,GO:0032969,"A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.",endosomal scaffold complex,cellular_component
70057,GO:0032970,"Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.",regulation of actin filament-based process,biological_process
70058,GO:0032971,"Any process that modulates the frequency, rate or extent of muscle filament sliding.",regulation of muscle filament sliding,biological_process
70059,GO:0032972,Any process that modulates the velocity of muscle filament sliding.,regulation of muscle filament sliding speed,biological_process
70060,GO:0032973,"The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.",amino acid export across plasma membrane,biological_process
70061,GO:0032974,"The directed movement of amino acids out of the vacuole, across the vacuolar membrane.",amino acid transmembrane export from vacuole,biological_process
70062,GO:0032975,The directed movement of amino acids into the vacuole across the vacuolar membrane.,amino acid transmembrane import into vacuole,biological_process
70063,GO:0032976,"The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.",release of matrix enzymes from mitochondria,biological_process
70064,GO:0032977,Binds transmembrane domain-containing proteins and mediates their integration into a membrane.,membrane insertase activity,molecular_function
70065,GO:0032979,"The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.",protein insertion into mitochondrial inner membrane from matrix,biological_process
70066,GO:0032980,"A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.",keratinocyte activation,biological_process
70067,GO:0032981,"The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.",mitochondrial respiratory chain complex I assembly,biological_process
70068,GO:0032982,"A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.",myosin filament,cellular_component
70069,GO:0032983,"An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.",kainate selective glutamate receptor complex,cellular_component
70070,GO:0032984,The disaggregation of a protein-containing macromolecular complex into its constituent components.,protein-containing complex disassembly,biological_process
70071,GO:0032985,The disaggregation of a protein-carbohydrate complex into its constituent components.,protein-carbohydrate complex disassembly,biological_process
70072,GO:0032986,The disaggregation of a protein-DNA complex into its constituent components.,protein-DNA complex disassembly,biological_process
70073,GO:0032987,The disaggregation of a protein-lipid complex into its constituent components.,protein-lipid complex disassembly,biological_process
70074,GO:0032988,The disaggregation of a protein-RNA complex into its constituent components.,protein-RNA complex disassembly,biological_process
70075,GO:0032989,The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system.,cellular anatomical entity morphogenesis,biological_process
70076,GO:0032991,"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.",protein-containing complex,cellular_component
70077,GO:0032992,A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other.,protein-carbohydrate complex,cellular_component
70078,GO:0032993,A macromolecular complex containing both protein and DNA molecules.,protein-DNA complex,cellular_component
70079,GO:0032994,A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other.,protein-lipid complex,cellular_component
70080,GO:0032995,"Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.",regulation of fungal-type cell wall biogenesis,biological_process
70081,GO:0032996,"A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.",Bcl3-Bcl10 complex,cellular_component
70082,GO:0032997,A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.,Fc receptor complex,cellular_component
70083,GO:0032998,A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.,Fc-epsilon receptor I complex,cellular_component
70084,GO:0032999,A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.,Fc-alpha receptor I complex,cellular_component
70085,GO:0033000,A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.,Fc-gamma receptor I complex,cellular_component
70086,GO:0033001,A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.,Fc-gamma receptor III complex,cellular_component
70087,GO:0033002,The expansion of a muscle cell population by cell division.,muscle cell proliferation,biological_process
70088,GO:0033003,"Any process that modulates the frequency, rate, or extent of mast cell activation.",regulation of mast cell activation,biological_process
70089,GO:0033004,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.",negative regulation of mast cell activation,biological_process
70090,GO:0033005,"Any process that activates or increases the frequency, rate, or extent of mast cell activation.",positive regulation of mast cell activation,biological_process
70091,GO:0033007,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.",negative regulation of mast cell activation involved in immune response,biological_process
70092,GO:0033008,"Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.",positive regulation of mast cell activation involved in immune response,biological_process
70093,GO:0033009,"A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.",nucleomorph,cellular_component
70094,GO:0033010,"A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.",paranodal junction,cellular_component
70095,GO:0033011,"A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are...",perinuclear theca,cellular_component
70096,GO:0033012,"A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.",porosome,cellular_component
70097,GO:0033013,"The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.",tetrapyrrole metabolic process,biological_process
70098,GO:0033014,"The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.",tetrapyrrole biosynthetic process,biological_process
70099,GO:0033015,"The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.",tetrapyrrole catabolic process,biological_process
70100,GO:0033016,The lipid bilayer surrounding a rhoptry.,rhoptry membrane,cellular_component
70101,GO:0033017,The lipid bilayer surrounding the sarcoplasmic reticulum.,sarcoplasmic reticulum membrane,cellular_component
70102,GO:0033018,The volume enclosed by the membranes of the sarcoplasmic reticulum.,sarcoplasmic reticulum lumen,cellular_component
70103,GO:0033021,The chemical reactions and pathways resulting in the formation of cyclopentanol.,cyclopentanol biosynthetic process,biological_process
70104,GO:0033022,The chemical reactions and pathways resulting in the breakdown of cyclopentanol.,cyclopentanol catabolic process,biological_process
70105,GO:0033023,The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,mast cell homeostasis,biological_process
70106,GO:0033024,"Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.",mast cell apoptotic process,biological_process
70107,GO:0033025,"Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.",regulation of mast cell apoptotic process,biological_process
70108,GO:0033026,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.",negative regulation of mast cell apoptotic process,biological_process
70109,GO:0033027,"Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.",positive regulation of mast cell apoptotic process,biological_process
70110,GO:0033028,"Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.",myeloid cell apoptotic process,biological_process
70111,GO:0033029,"Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.",regulation of neutrophil apoptotic process,biological_process
70112,GO:0033030,"Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.",negative regulation of neutrophil apoptotic process,biological_process
70113,GO:0033031,"Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.",positive regulation of neutrophil apoptotic process,biological_process
70114,GO:0033032,"Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.",regulation of myeloid cell apoptotic process,biological_process
70115,GO:0033033,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.",negative regulation of myeloid cell apoptotic process,biological_process
70116,GO:0033034,"Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.",positive regulation of myeloid cell apoptotic process,biological_process
70117,GO:0033036,"Any process in which a macromolecule is transported to, or maintained in, a specific location.",macromolecule localization,biological_process
70118,GO:0033037,"Any process in which a polysaccharide is transported to, or maintained in, a specific location.",polysaccharide localization,biological_process
70119,GO:0033038,Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.,bitter taste receptor activity,molecular_function
70120,GO:0033039,Enables the transmembrane transfer of an ion by a channel that opens when a soluble salty compound has been bound by the channel complex or one of its constituent parts.,ionotropic salty taste receptor activity,molecular_function
70121,GO:0033040,Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.,sour taste receptor activity,molecular_function
70122,GO:0033041,Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.,sweet taste receptor activity,molecular_function
70123,GO:0033042,"Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.",umami taste receptor activity,molecular_function
70124,GO:0033043,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.",regulation of organelle organization,biological_process
70125,GO:0033044,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.",regulation of chromosome organization,biological_process
70126,GO:0033045,"Any process that modulates the frequency, rate or extent of sister chromatid segregation.",regulation of sister chromatid segregation,biological_process
70127,GO:0033046,"Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.",negative regulation of sister chromatid segregation,biological_process
70128,GO:0033047,"Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.",regulation of mitotic sister chromatid segregation,biological_process
70129,GO:0033048,"Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.",negative regulation of mitotic sister chromatid segregation,biological_process
70130,GO:0033050,"The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.",clavulanic acid biosynthetic process,biological_process
70131,GO:0033051,"The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.",aminophosphonate metabolic process,biological_process
70132,GO:0033058,Self-propelled movement of a cell or organism from one location to another along an axis.,directional locomotion,biological_process
70133,GO:0033059,The deposition or aggregation of coloring matter in a cell.,cellular pigmentation,biological_process
70134,GO:0033060,"The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.",ocellus pigmentation,biological_process
70135,GO:0033061,"A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange.",DNA recombinase mediator complex,cellular_component
70136,GO:0033063,"A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.",Rad51B-Rad51C-Rad51D-XRCC2 complex,cellular_component
70137,GO:0033064,"A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.",XRCC2-RAD51D complex,cellular_component
70138,GO:0033065,"A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.",Rad51C-XRCC3 complex,cellular_component
70139,GO:0033066,"A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.",Rad51B-Rad51C complex,cellular_component
70140,GO:0033067,"The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.",macrolide metabolic process,biological_process
70141,GO:0033068,"The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.",macrolide biosynthetic process,biological_process
70142,GO:0033070,"The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.",ansamycin biosynthetic process,biological_process
70143,GO:0033072,"The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazac...",vancomycin biosynthetic process,biological_process
70144,GO:0033073,"The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.",pinene metabolic process,biological_process
70145,GO:0033074,"The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.",pinene catabolic process,biological_process
70146,GO:0033075,"The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.",isoquinoline alkaloid biosynthetic process,biological_process
70147,GO:0033076,"The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.",isoquinoline alkaloid metabolic process,biological_process
70148,GO:0033077,The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.,T cell differentiation in thymus,biological_process
70149,GO:0033078,The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.,extrathymic T cell differentiation,biological_process
70150,GO:0033079,The expansion of an immature T cell population by cell division.,immature T cell proliferation,biological_process
70151,GO:0033080,The expansion of an immature T cell population by cell division in the thymus.,immature T cell proliferation in thymus,biological_process
70152,GO:0033081,"Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.",regulation of T cell differentiation in thymus,biological_process
70153,GO:0033082,"Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.",regulation of extrathymic T cell differentiation,biological_process
70154,GO:0033083,"Any process that modulates the frequency, rate or extent of immature T cell proliferation.",regulation of immature T cell proliferation,biological_process
70155,GO:0033084,"Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.",regulation of immature T cell proliferation in thymus,biological_process
70156,GO:0033085,"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.",negative regulation of T cell differentiation in thymus,biological_process
70157,GO:0033086,"Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.",negative regulation of extrathymic T cell differentiation,biological_process
70158,GO:0033087,"Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.",negative regulation of immature T cell proliferation,biological_process
70159,GO:0033088,"Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.",negative regulation of immature T cell proliferation in thymus,biological_process
70160,GO:0033089,"Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.",positive regulation of T cell differentiation in thymus,biological_process
70161,GO:0033090,"Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.",positive regulation of extrathymic T cell differentiation,biological_process
70162,GO:0033091,"Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.",positive regulation of immature T cell proliferation,biological_process
70163,GO:0033092,"Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.",positive regulation of immature T cell proliferation in thymus,biological_process
70164,GO:0033093,"A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exoc...",Weibel-Palade body,cellular_component
70165,GO:0033094,Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline.,putrescine:2-oxoglutarate transaminase activity,molecular_function
70166,GO:0033095,"A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.",aleurone grain,cellular_component
70167,GO:0033096,The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,amyloplast envelope,cellular_component
70168,GO:0033097,Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.,amyloplast membrane,cellular_component
70169,GO:0033098,"The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.",amyloplast inner membrane,cellular_component
70170,GO:0033099,"A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.",attachment organelle,cellular_component
70171,GO:0033100,"A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.",NuA3 histone acetyltransferase complex,cellular_component
70172,GO:0033101,The portion of the plasma membrane surrounding a cellular bud.,cellular bud membrane,cellular_component
70173,GO:0033102,The lipid bilayer surrounding an acidocalcisome.,acidocalcisome membrane,cellular_component
70174,GO:0033103,The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.,protein secretion by the type VI secretion system,biological_process
70175,GO:0033104,A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.,type VI protein secretion system complex,cellular_component
70176,GO:0033105,"The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.",chlorosome envelope,cellular_component
70177,GO:0033106,The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network.,cis-Golgi network membrane,cellular_component
70178,GO:0033107,"A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).",Cvt vesicle,cellular_component
70179,GO:0033108,"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex or between respiratory chain complexes to form high-order structures.",mitochondrial respiratory chain complex assembly,biological_process
70180,GO:0033110,"Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.",Cvt vesicle membrane,cellular_component
70181,GO:0033111,"The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.",attachment organelle membrane,cellular_component
70182,GO:0033112,The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,cyanelle envelope,cellular_component
70183,GO:0033113,Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.,cyanelle membrane,cellular_component
70184,GO:0033114,The volume enclosed by a cyanelle thylakoid membrane.,cyanelle thylakoid lumen,cellular_component
70185,GO:0033115,The lipid bilayer membrane of any thylakoid within a cyanelle.,cyanelle thylakoid membrane,cellular_component
70186,GO:0033116,The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.,endoplasmic reticulum-Golgi intermediate compartment membrane,cellular_component
70187,GO:0033117,A vesicle filled with crystalline protein that shows sequence similarities with various esterases.,esterosome,cellular_component
70188,GO:0033118,The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.,esterosome membrane,cellular_component
70189,GO:0033119,"Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.",negative regulation of RNA splicing,biological_process
70190,GO:0033120,"Any process that activates or increases the frequency, rate or extent of RNA splicing.",positive regulation of RNA splicing,biological_process
70191,GO:0033121,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.",regulation of purine nucleotide catabolic process,biological_process
70192,GO:0033122,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.",negative regulation of purine nucleotide catabolic process,biological_process
70193,GO:0033123,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.",positive regulation of purine nucleotide catabolic process,biological_process
70194,GO:0033130,Binding to an acetylcholine receptor.,acetylcholine receptor binding,molecular_function
70195,GO:0033132,"Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.",negative regulation of glucokinase activity,biological_process
70196,GO:0033134,"Binding to a ubiquitin activating enzyme, any of the E1 proteins.",ubiquitin activating enzyme binding,molecular_function
70197,GO:0033135,"Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.",regulation of peptidyl-serine phosphorylation,biological_process
70198,GO:0033137,"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.",negative regulation of peptidyl-serine phosphorylation,biological_process
70199,GO:0033138,"Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.",positive regulation of peptidyl-serine phosphorylation,biological_process
70200,GO:0033139,"Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",regulation of peptidyl-serine phosphorylation of STAT protein,biological_process
70201,GO:0033140,"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",negative regulation of peptidyl-serine phosphorylation of STAT protein,biological_process
70202,GO:0033141,"Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",positive regulation of peptidyl-serine phosphorylation of STAT protein,biological_process
70203,GO:0033142,Binding to a nuclear progesterone receptor.,nuclear progesterone receptor binding,molecular_function
70204,GO:0033143,"Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.",regulation of intracellular steroid hormone receptor signaling pathway,biological_process
70205,GO:0033144,"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.",negative regulation of intracellular steroid hormone receptor signaling pathway,biological_process
70206,GO:0033145,"Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.",positive regulation of intracellular steroid hormone receptor signaling pathway,biological_process
70207,GO:0033146,"Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.",regulation of intracellular estrogen receptor signaling pathway,biological_process
70208,GO:0033147,"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.",negative regulation of intracellular estrogen receptor signaling pathway,biological_process
70209,GO:0033148,"Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.",positive regulation of intracellular estrogen receptor signaling pathway,biological_process
70210,GO:0033149,"Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.",FFAT motif binding,molecular_function
70211,GO:0033150,"A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.",cytoskeletal calyx,cellular_component
70212,GO:0033151,"The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).",V(D)J recombination,biological_process
70213,GO:0033152,"The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.",immunoglobulin V(D)J recombination,biological_process
70214,GO:0033153,"The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).",T cell receptor V(D)J recombination,biological_process
70215,GO:0033154,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).,ABC-type oligogalacturonide transporter activity,molecular_function
70216,GO:0033156,"The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",oligogalacturonide transport,biological_process
70217,GO:0033157,"Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.",regulation of intracellular protein transport,biological_process
70218,GO:0033161,"Binding to a mitogen-activated protein kinase kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase kinase.",mitogen-activated protein kinase kinase kinase kinase binding,molecular_function
70219,GO:0033162,The lipid bilayer surrounding a melanosome.,melanosome membrane,cellular_component
70220,GO:0033163,The lipid bilayer surrounding a microneme.,microneme membrane,cellular_component
70221,GO:0033164,"Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose to Man(8)GlcNAc or Man(9)GlcNAc via an alpha-(1->6)-D-mannosyl-D-mannose linkage to form Man(9)GlcNAc or Man(10)GlcNAc, respectively. This is the first step specific to the biosynthesis of the outer chain of yeast mannoproteins.","initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity",molecular_function
70222,GO:0033165,A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.,interphotoreceptor matrix,cellular_component
70223,GO:0033166,"A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.",hyaline layer,cellular_component
70224,GO:0033167,"A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.",ARC complex,cellular_component
70225,GO:0033172,The proteinaceous structure surrounding a gas vesicle.,gas vesicle shell,cellular_component
70226,GO:0033173,"Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineu...",calcineurin-NFAT signaling cascade,biological_process
70227,GO:0033176,A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hy...,proton-transporting V-type ATPase complex,cellular_component
70228,GO:0033177,"A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.","proton-transporting two-sector ATPase complex, proton-transporting domain",cellular_component
70229,GO:0033178,"A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.","proton-transporting two-sector ATPase complex, catalytic domain",cellular_component
70230,GO:0033179,"A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.","proton-transporting V-type ATPase, V0 domain",cellular_component
70231,GO:0033180,"A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.","proton-transporting V-type ATPase, V1 domain",cellular_component
70232,GO:0033181,A proton-transporting two-sector ATPase complex found in the plasma membrane.,plasma membrane proton-transporting V-type ATPase complex,cellular_component
70233,GO:0033185,"A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.",dolichol-phosphate-mannose synthase complex,cellular_component
70234,GO:0033186,"A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.",CAF-1 complex,cellular_component
70235,GO:0033188,"Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.",sphingomyelin synthase activity,molecular_function
70236,GO:0033189,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.",response to vitamin A,biological_process
70237,GO:0033190,Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.,solanapyrone synthase activity,molecular_function
70238,GO:0033191,Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate.,macrophomate synthase activity,molecular_function
70239,GO:0033192,"Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.",calmodulin-dependent protein phosphatase activity,molecular_function
70240,GO:0033193,"A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.",Lsd1/2 complex,cellular_component
70241,GO:0033194,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.",response to hydroperoxide,biological_process
70242,GO:0033195,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.",response to alkyl hydroperoxide,biological_process
70243,GO:0033196,Catalysis of the reaction: tryparedoxin + H2O2 = tryparedoxin disulfide + H2O.,tryparedoxin peroxidase activity,molecular_function
70244,GO:0033197,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.",response to vitamin E,biological_process
70245,GO:0033198,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.",response to ATP,biological_process
70246,GO:0033200,"Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = ADP + 4,5-bisdiphosphoinositol-1D-myo-inositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = ADP + 5,6-bisdiphosphoinositol-1D-myo-inositol (1,2,3,4)tetrakisphosphate.",diphosphoinositol pentakisphosphate 5-kinase activity,molecular_function
70247,GO:0033202,A protein complex that possesses DNA helicase activity.,DNA helicase complex,cellular_component
70248,GO:0033203,A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.,DNA helicase A complex,cellular_component
70249,GO:0033204,Binding to RNA subunit of ribonuclease P.,ribonuclease P RNA binding,molecular_function
70250,GO:0033206,"A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.",meiotic cytokinesis,biological_process
70251,GO:0033209,"The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",tumor necrosis factor-mediated signaling pathway,biological_process
70252,GO:0033210,"The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.",leptin-mediated signaling pathway,biological_process
70253,GO:0033211,"The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",adiponectin-activated signaling pathway,biological_process
70254,GO:0033212,The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.,iron import into cell,biological_process
70255,GO:0033214,"A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores is imported into the cell by transmembrane transport or endocytosis.",siderophore-iron import into cell,biological_process
70256,GO:0033215,A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.,reductive iron assimilation,biological_process
70257,GO:0033219,"Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2.",urea binding,molecular_function
70258,GO:0033221,Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).,ATPase-coupled urea transmembrane transporter activity,molecular_function
70259,GO:0033222,Binding to the D- or L-enantiomer of xylose.,xylose binding,molecular_function
70260,GO:0033223,"The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",2-aminoethylphosphonate transport,biological_process
70261,GO:0033225,Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).,ATPase-coupled 2-aminoethylphosphonate transporter activity,molecular_function
70262,GO:0033226,Binding to 2-aminoethylphosphonate.,2-aminoethylphosphonate binding,molecular_function
70263,GO:0033227,"The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",dsRNA transport,biological_process
70264,GO:0033228,"The directed movement of L-cysteine from inside of a cell, across the plasma membrane and into the extracellular region.",L-cysteine export across plasma membrane,biological_process
70265,GO:0033229,Enables the transfer of L-cysteine from one side of a membrane to the other.,L-cysteine transmembrane transporter activity,molecular_function
70266,GO:0033230,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-cysteine(in) = ADP + H+ + L-cysteine(out) + phosphate.,ABC-type L-cysteine transporter activity,molecular_function
70267,GO:0033231,The directed movement of carbohydrates out of a cell or organelle.,carbohydrate export,biological_process
70268,GO:0033232,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).,ABC-type D-methionine transporter activity,molecular_function
70269,GO:0033233,"Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.",regulation of protein sumoylation,biological_process
70270,GO:0033234,"Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.",negative regulation of protein sumoylation,biological_process
70271,GO:0033235,"Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.",positive regulation of protein sumoylation,biological_process
70272,GO:0033238,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.",regulation of amine metabolic process,biological_process
70273,GO:0033239,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.",negative regulation of amine metabolic process,biological_process
70274,GO:0033240,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.",positive regulation of amine metabolic process,biological_process
70275,GO:0033241,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.",regulation of amine catabolic process,biological_process
70276,GO:0033242,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.",negative regulation of amine catabolic process,biological_process
70277,GO:0033243,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.",positive regulation of amine catabolic process,biological_process
70278,GO:0033246,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.",positive regulation of penicillin metabolic process,biological_process
70279,GO:0033247,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.",regulation of penicillin catabolic process,biological_process
70280,GO:0033248,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.",negative regulation of penicillin catabolic process,biological_process
70281,GO:0033249,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.",positive regulation of penicillin catabolic process,biological_process
70282,GO:0033252,"Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.",regulation of beta-lactamase activity,biological_process
70283,GO:0033254,"A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1...",vacuolar transporter chaperone complex,cellular_component
70284,GO:0033255,"A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.",SAS acetyltransferase complex,cellular_component
70285,GO:0033256,"A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.",I-kappaB/NF-kappaB complex,cellular_component
70286,GO:0033257,"A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.",Bcl3/NF-kappaB2 complex,cellular_component
70287,GO:0033258,The chemical reactions and pathways involving plastid DNA.,plastid DNA metabolic process,biological_process
70288,GO:0033259,The process in which new strands of DNA are synthesized in a plastid.,plastid DNA replication,biological_process
70289,GO:0033260,The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.,nuclear DNA replication,biological_process
70290,GO:0033262,"Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.",regulation of nuclear cell cycle DNA replication,biological_process
70291,GO:0033263,"A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.",CORVET complex,cellular_component
70292,GO:0033265,"Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.",choline binding,molecular_function
70293,GO:0033266,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.",ABC-type choline transporter activity,molecular_function
70294,GO:0033268,An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.,node of Ranvier,cellular_component
70295,GO:0033269,An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.,internode region of axon,cellular_component
70296,GO:0033270,An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.,paranode region of axon,cellular_component
70297,GO:0033271,"The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",myo-inositol phosphate transport,biological_process
70298,GO:0033272,"The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",myo-inositol hexakisphosphate transport,biological_process
70299,GO:0033273,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.",response to vitamin,biological_process
70300,GO:0033274,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.",response to vitamin B2,biological_process
70301,GO:0033275,The sliding movement of actin thin filaments and myosin thick filaments past each other.,actin-myosin filament sliding,biological_process
70302,GO:0033276,"A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.",transcription factor TFTC complex,cellular_component
70303,GO:0033278,"The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.",cell proliferation in midbrain,biological_process
70304,GO:0033280,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.",response to vitamin D,biological_process
70305,GO:0033281,A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.,TAT protein transport complex,cellular_component
70306,GO:0033282,A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.,protein C inhibitor-acrosin complex,cellular_component
70307,GO:0033284,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).,ATPase-coupled carboxylic acid transmembrane transporter activity,molecular_function
70308,GO:0033285,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).,ATPase-coupled monocarboxylic acid transmembrane transporter activity,molecular_function
70309,GO:0033286,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).,ATPase-coupled ectoine transmembrane transporter activity,molecular_function
70310,GO:0033288,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).,ATPase-coupled hydroxyectoine transmembrane transporter activity,molecular_function
70311,GO:0033289,A microtubule located such that it threads through the conoid and projects through the polar ring.,intraconoid microtubule,cellular_component
70312,GO:0033290,"The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC.",eukaryotic 48S preinitiation complex,cellular_component
70313,GO:0033291,"A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.",eukaryotic 80S initiation complex,cellular_component
70314,GO:0033292,"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.",T-tubule organization,biological_process
70315,GO:0033293,"Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).",monocarboxylic acid binding,molecular_function
70316,GO:0033294,"Binding to ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.",ectoine binding,molecular_function
70317,GO:0033295,Binding to hydroxyectoine.,hydroxyectoine binding,molecular_function
70318,GO:0033296,Binding to the D- or L-enantiomer of rhamnose.,rhamnose binding,molecular_function
70319,GO:0033298,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.",contractile vacuole organization,biological_process
70320,GO:0033299,The controlled release of lysosomal enzymes by a cell.,secretion of lysosomal enzymes,biological_process
70321,GO:0033300,"Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.",dehydroascorbic acid transmembrane transporter activity,molecular_function
70322,GO:0033301,"A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).",cell cycle comprising mitosis without cytokinesis,biological_process
70323,GO:0033303,The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.,quercetin O-glucoside biosynthetic process,biological_process
70324,GO:0033305,The chemical reactions and pathways leading to the formation of chlorophyll a.,chlorophyll a biosynthetic process,biological_process
70325,GO:0033306,"The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.",phytol metabolic process,biological_process
70326,GO:0033307,"A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.",phytol salvage,biological_process
70327,GO:0033308,The directed movement of hydroxyectoine across a membrane by means of some agent such as a transporter or a pore.,hydroxyectoine transmembrane transport,biological_process
70328,GO:0033309,"A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p.",SBF transcription complex,cellular_component
70329,GO:0033310,The chemical reactions and pathways leading to the breakdown of chlorophyll a.,chlorophyll a catabolic process,biological_process
70330,GO:0033313,A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.,meiotic cell cycle checkpoint signaling,biological_process
70331,GO:0033314,A signal transduction process that contributes to a mitotic DNA replication checkpoint.,mitotic DNA replication checkpoint signaling,biological_process
70332,GO:0033315,A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete.,meiotic G2/MI DNA replication checkpoint signaling,biological_process
70333,GO:0033316,"A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.",meiotic spindle assembly checkpoint signaling,biological_process
70334,GO:0033319,"The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.",UDP-D-xylose metabolic process,biological_process
70335,GO:0033320,"The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.",UDP-D-xylose biosynthetic process,biological_process
70336,GO:0033322,"The chemical reactions and pathways resulting in the formation of L-homomethionine, a non-protein amino acid synthesized from L-methionine via chain elongation.",L-homomethionine biosynthetic process,biological_process
70337,GO:0033326,"The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.",cerebrospinal fluid secretion,biological_process
70338,GO:0033327,"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.",Leydig cell differentiation,biological_process
70339,GO:0033330,The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.,kaempferol O-glucoside biosynthetic process,biological_process
70340,GO:0033331,"The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.",ent-kaurene metabolic process,biological_process
70341,GO:0033332,"The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.",ent-kaurene biosynthetic process,biological_process
70342,GO:0033333,"The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.",fin development,biological_process
70343,GO:0033334,The process in which the anatomical structures of a fin are generated and organized.,fin morphogenesis,biological_process
70344,GO:0033335,"The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.",anal fin development,biological_process
70345,GO:0033336,"The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.",caudal fin development,biological_process
70346,GO:0033337,"The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.",dorsal fin development,biological_process
70347,GO:0033338,"The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.",medial fin development,biological_process
70348,GO:0033339,"The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.",pectoral fin development,biological_process
70349,GO:0033340,"The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.",pelvic fin development,biological_process
70350,GO:0033344,"The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.",cholesterol efflux,biological_process
70351,GO:0033347,"The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.",tetrose metabolic process,biological_process
70352,GO:0033348,"The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.",tetrose biosynthetic process,biological_process
70353,GO:0033350,"The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.",apiose biosynthetic process,biological_process
70354,GO:0033352,"The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.",UDP-D-apiose biosynthetic process,biological_process
70355,GO:0033353,"A cyclic series of interconversions involving S-adenosyl-L-homocysteine, L-homocysteine, L-methionine and S-adenosyl-L-methionine (SAM). Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of L-methionine.",L-methionine cycle,biological_process
70356,GO:0033354,"A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.",chlorophyll cycle,biological_process
70357,GO:0033355,"A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges H2O2 and reduces it to water, with concomitant oxidation of NADPH.",ascorbate glutathione cycle,biological_process
70358,GO:0033356,"The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.",UDP-L-arabinose metabolic process,biological_process
70359,GO:0033357,"The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.",L-arabinose biosynthetic process,biological_process
70360,GO:0033358,"The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.",UDP-L-arabinose biosynthetic process,biological_process
70361,GO:0033363,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.",secretory granule organization,biological_process
70362,GO:0033364,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.",mast cell secretory granule organization,biological_process
70363,GO:0033365,"A process in which a protein is transported to, or maintained in, a location within an organelle.",protein localization to organelle,biological_process
70364,GO:0033366,"A process in which a protein is transported to, or maintained in, a location within a secretory granule.",protein localization to secretory granule,biological_process
70365,GO:0033367,"A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.",protein localization to mast cell secretory granule,biological_process
70366,GO:0033368,"Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.",protease localization to mast cell secretory granule,biological_process
70367,GO:0033369,The directed movement of a protein to a location within a secretory granule in a mast cell.,establishment of protein localization to mast cell secretory granule,biological_process
70368,GO:0033370,A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.,maintenance of protein location in mast cell secretory granule,biological_process
70369,GO:0033371,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.",T cell secretory granule organization,biological_process
70370,GO:0033372,The directed movement of a protease to a location within a secretory granule in a mast cell.,establishment of protease localization to mast cell secretory granule,biological_process
70371,GO:0033373,A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.,maintenance of protease location in mast cell secretory granule,biological_process
70372,GO:0033374,"A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.",protein localization to T cell secretory granule,biological_process
70373,GO:0033375,"Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.",protease localization to T cell secretory granule,biological_process
70374,GO:0033376,The directed movement of a protein to a location within a secretory granule in a T cell.,establishment of protein localization to T cell secretory granule,biological_process
70375,GO:0033377,A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.,maintenance of protein location in T cell secretory granule,biological_process
70376,GO:0033378,The directed movement of a protease to a location within a secretory granule in a T cell.,establishment of protease localization to T cell secretory granule,biological_process
70377,GO:0033379,A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.,maintenance of protease location in T cell secretory granule,biological_process
70378,GO:0033380,"Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.",granzyme B localization to T cell secretory granule,biological_process
70379,GO:0033381,The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.,establishment of granzyme B localization to T cell secretory granule,biological_process
70380,GO:0033382,A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.,maintenance of granzyme B location in T cell secretory granule,biological_process
70381,GO:0033383,"The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.",geranyl diphosphate metabolic process,biological_process
70382,GO:0033384,The chemical reactions and pathways resulting in the formation of geranyl diphosphate.,geranyl diphosphate biosynthetic process,biological_process
70383,GO:0033385,"The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.",geranylgeranyl diphosphate metabolic process,biological_process
70384,GO:0033386,The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.,geranylgeranyl diphosphate biosynthetic process,biological_process
70385,GO:0033391,"A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).",chromatoid body,cellular_component
70386,GO:0033398,"The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.",zeatin biosynthetic process,biological_process
70387,GO:0033401,A triplet codon-amino acid adaptor activity that recognizes a UUU codon.,UUU codon-amino acid adaptor activity,molecular_function
70388,GO:0033402,A triplet codon-amino acid adaptor activity that recognizes a UUC codon.,UUC codon-amino acid adaptor activity,molecular_function
70389,GO:0033403,A triplet codon-amino acid adaptor activity that recognizes a UUA codon.,UUA codon-amino acid adaptor activity,molecular_function
70390,GO:0033404,A triplet codon-amino acid adaptor activity that recognizes a UUG codon.,UUG codon-amino acid adaptor activity,molecular_function
70391,GO:0033405,A triplet codon-amino acid adaptor activity that recognizes a UCU codon.,UCU codon-amino acid adaptor activity,molecular_function
70392,GO:0033406,A triplet codon-amino acid adaptor activity that recognizes a UCC codon.,UCC codon-amino acid adaptor activity,molecular_function
70393,GO:0033407,A triplet codon-amino acid adaptor activity that recognizes a UCA codon.,UCA codon-amino acid adaptor activity,molecular_function
70394,GO:0033408,A triplet codon-amino acid adaptor activity that recognizes a UCG codon.,UCG codon-amino acid adaptor activity,molecular_function
70395,GO:0033409,A triplet codon-amino acid adaptor activity that recognizes a UAU codon.,UAU codon-amino acid adaptor activity,molecular_function
70396,GO:0033410,A triplet codon-amino acid adaptor activity that recognizes a UAC codon.,UAC codon-amino acid adaptor activity,molecular_function
70397,GO:0033411,A triplet codon-amino acid adaptor activity that recognizes a UAA codon.,UAA codon-amino acid adaptor activity,molecular_function
70398,GO:0033412,A triplet codon-amino acid adaptor activity that recognizes a UAG codon.,UAG codon-amino acid adaptor activity,molecular_function
70399,GO:0033413,A triplet codon-amino acid adaptor activity that recognizes a UGU codon.,UGU codon-amino acid adaptor activity,molecular_function
70400,GO:0033414,A triplet codon-amino acid adaptor activity that recognizes a UGC codon.,UGC codon-amino acid adaptor activity,molecular_function
70401,GO:0033415,A triplet codon-amino acid adaptor activity that recognizes a UGA codon.,UGA codon-amino acid adaptor activity,molecular_function
70402,GO:0033416,A triplet codon-amino acid adaptor activity that recognizes a UGG codon.,UGG codon-amino acid adaptor activity,molecular_function
70403,GO:0033417,A triplet codon-amino acid adaptor activity that recognizes a CUU codon.,CUU codon-amino acid adaptor activity,molecular_function
70404,GO:0033418,A triplet codon-amino acid adaptor activity that recognizes a CUC codon.,CUC codon-amino acid adaptor activity,molecular_function
70405,GO:0033419,A triplet codon-amino acid adaptor activity that recognizes a CUA codon.,CUA codon-amino acid adaptor activity,molecular_function
70406,GO:0033420,A triplet codon-amino acid adaptor activity that recognizes a CUG codon.,CUG codon-amino acid adaptor activity,molecular_function
70407,GO:0033421,A triplet codon-amino acid adaptor activity that recognizes a CCU codon.,CCU codon-amino acid adaptor activity,molecular_function
70408,GO:0033422,A triplet codon-amino acid adaptor activity that recognizes a CCC codon.,CCC codon-amino acid adaptor activity,molecular_function
70409,GO:0033423,A triplet codon-amino acid adaptor activity that recognizes a CCA codon.,CCA codon-amino acid adaptor activity,molecular_function
70410,GO:0033424,A triplet codon-amino acid adaptor activity that recognizes a CCG codon.,CCG codon-amino acid adaptor activity,molecular_function
70411,GO:0033425,A triplet codon-amino acid adaptor activity that recognizes a CAU codon.,CAU codon-amino acid adaptor activity,molecular_function
70412,GO:0033426,A triplet codon-amino acid adaptor activity that recognizes a CAC codon.,CAC codon-amino acid adaptor activity,molecular_function
70413,GO:0033427,A triplet codon-amino acid adaptor activity that recognizes a CAA codon.,CAA codon-amino acid adaptor activity,molecular_function
70414,GO:0033428,A triplet codon-amino acid adaptor activity that recognizes a CAG codon.,CAG codon-amino acid adaptor activity,molecular_function
70415,GO:0033429,A triplet codon-amino acid adaptor activity that recognizes a CGU codon.,CGU codon-amino acid adaptor activity,molecular_function
70416,GO:0033430,A triplet codon-amino acid adaptor activity that recognizes a CGC codon.,CGC codon-amino acid adaptor activity,molecular_function
70417,GO:0033431,A triplet codon-amino acid adaptor activity that recognizes a CGA codon.,CGA codon-amino acid adaptor activity,molecular_function
70418,GO:0033432,A triplet codon-amino acid adaptor activity that recognizes a CGG codon.,CGG codon-amino acid adaptor activity,molecular_function
70419,GO:0033433,A triplet codon-amino acid adaptor activity that recognizes an AUU codon.,AUU codon-amino acid adaptor activity,molecular_function
70420,GO:0033434,A triplet codon-amino acid adaptor activity that recognizes an AUC codon.,AUC codon-amino acid adaptor activity,molecular_function
70421,GO:0033435,A triplet codon-amino acid adaptor activity that recognizes an AUA codon.,AUA codon-amino acid adaptor activity,molecular_function
70422,GO:0033436,A triplet codon-amino acid adaptor activity that recognizes an AUG codon.,AUG codon-amino acid adaptor activity,molecular_function
70423,GO:0033437,A triplet codon-amino acid adaptor activity that recognizes an ACU codon.,ACU codon-amino acid adaptor activity,molecular_function
70424,GO:0033438,A triplet codon-amino acid adaptor activity that recognizes an ACC codon.,ACC codon-amino acid adaptor activity,molecular_function
70425,GO:0033439,A triplet codon-amino acid adaptor activity that recognizes an ACA codon.,ACA codon-amino acid adaptor activity,molecular_function
70426,GO:0033440,A triplet codon-amino acid adaptor activity that recognizes an ACG codon.,ACG codon-amino acid adaptor activity,molecular_function
70427,GO:0033441,A triplet codon-amino acid adaptor activity that recognizes an AAU codon.,AAU codon-amino acid adaptor activity,molecular_function
70428,GO:0033442,A triplet codon-amino acid adaptor activity that recognizes an AAC codon.,AAC codon-amino acid adaptor activity,molecular_function
70429,GO:0033443,A triplet codon-amino acid adaptor activity that recognizes an AAA codon.,AAA codon-amino acid adaptor activity,molecular_function
70430,GO:0033444,A triplet codon-amino acid adaptor activity that recognizes an AAG codon.,AAG codon-amino acid adaptor activity,molecular_function
70431,GO:0033445,A triplet codon-amino acid adaptor activity that recognizes an AGU codon.,AGU codon-amino acid adaptor activity,molecular_function
70432,GO:0033446,A triplet codon-amino acid adaptor activity that recognizes an AGC codon.,AGC codon-amino acid adaptor activity,molecular_function
70433,GO:0033447,A triplet codon-amino acid adaptor activity that recognizes an AGA codon.,AGA codon-amino acid adaptor activity,molecular_function
70434,GO:0033448,A triplet codon-amino acid adaptor activity that recognizes an AGG codon.,AGG codon-amino acid adaptor activity,molecular_function
70435,GO:0033449,A triplet codon-amino acid adaptor activity that recognizes a GUU codon.,GUU codon-amino acid adaptor activity,molecular_function
70436,GO:0033450,A triplet codon-amino acid adaptor activity that recognizes a GUC codon.,GUC codon-amino acid adaptor activity,molecular_function
70437,GO:0033451,A triplet codon-amino acid adaptor activity that recognizes a GUA codon.,GUA codon-amino acid adaptor activity,molecular_function
70438,GO:0033452,A triplet codon-amino acid adaptor activity that recognizes a GUG codon.,GUG codon-amino acid adaptor activity,molecular_function
70439,GO:0033453,A triplet codon-amino acid adaptor activity that recognizes a GCU codon.,GCU codon-amino acid adaptor activity,molecular_function
70440,GO:0033454,A triplet codon-amino acid adaptor activity that recognizes a GCC codon.,GCC codon-amino acid adaptor activity,molecular_function
70441,GO:0033455,A triplet codon-amino acid adaptor activity that recognizes a GCA codon.,GCA codon-amino acid adaptor activity,molecular_function
70442,GO:0033456,A triplet codon-amino acid adaptor activity that recognizes a GCG codon.,GCG codon-amino acid adaptor activity,molecular_function
70443,GO:0033457,A triplet codon-amino acid adaptor activity that recognizes a GAU codon.,GAU codon-amino acid adaptor activity,molecular_function
70444,GO:0033458,A triplet codon-amino acid adaptor activity that recognizes a GAC codon.,GAC codon-amino acid adaptor activity,molecular_function
70445,GO:0033459,A triplet codon-amino acid adaptor activity that recognizes a GAA codon.,GAA codon-amino acid adaptor activity,molecular_function
70446,GO:0033460,A triplet codon-amino acid adaptor activity that recognizes a GAG codon.,GAG codon-amino acid adaptor activity,molecular_function
70447,GO:0033461,A triplet codon-amino acid adaptor activity that recognizes a GGU codon.,GGU codon-amino acid adaptor activity,molecular_function
70448,GO:0033462,A triplet codon-amino acid adaptor activity that recognizes a GGC codon.,GGC codon-amino acid adaptor activity,molecular_function
70449,GO:0033463,A triplet codon-amino acid adaptor activity that recognizes a GGA codon.,GGA codon-amino acid adaptor activity,molecular_function
70450,GO:0033464,A triplet codon-amino acid adaptor activity that recognizes a GGG codon.,GGG codon-amino acid adaptor activity,molecular_function
70451,GO:0033465,"The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.",cis-zeatin biosynthetic process,biological_process
70452,GO:0033466,"The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.",trans-zeatin biosynthetic process,biological_process
70453,GO:0033468,"The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.",CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process,biological_process
70454,GO:0033470,"The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.",gibberellin 12 biosynthetic process,biological_process
70455,GO:0033472,"The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.",GDP-L-galactose biosynthetic process,biological_process
70456,GO:0033473,"The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.",indoleacetic acid conjugate metabolic process,biological_process
70457,GO:0033474,"The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.",indoleacetic acid conjugate biosynthetic process,biological_process
70458,GO:0033475,"The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.",indoleacetic acid amide conjugate biosynthetic process,biological_process
70459,GO:0033477,"The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.",S-methylmethionine metabolic process,biological_process
70460,GO:0033480,"The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.",UDP-D-galacturonate biosynthetic process,biological_process
70461,GO:0033481,"The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.",galacturonate biosynthetic process,biological_process
70462,GO:0033482,"The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.",D-galacturonate biosynthetic process,biological_process
70463,GO:0033484,A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell.,intracellular nitric oxide homeostasis,biological_process
70464,GO:0033485,"The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.",cyanidin 3-O-glucoside biosynthetic process,biological_process
70465,GO:0033486,"The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.",delphinidin 3-O-glucoside biosynthetic process,biological_process
70466,GO:0033487,"The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.",pelargonidin 3-O-glucoside biosynthetic process,biological_process
70467,GO:0033491,"The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.",coniferin metabolic process,biological_process
70468,GO:0033493,"The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.",esculetin biosynthetic process,biological_process
70469,GO:0033494,"The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.",ferulate metabolic process,biological_process
70470,GO:0033495,"The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.",ferulate biosynthetic process,biological_process
70471,GO:0033497,"The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.",sinapate biosynthetic process,biological_process
70472,GO:0033498,"The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.",galactose catabolic process via D-galactonate,biological_process
70473,GO:0033499,"The chemical reactions and pathways resulting in the breakdown of beta-D-galactose, via the intermediate UDP-galactose.","beta-D-galactose catabolic process via UDP-galactose, Leloir pathway",biological_process
70474,GO:0033500,A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.,carbohydrate homeostasis,biological_process
70475,GO:0033503,"A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2.",HULC complex,cellular_component
70476,GO:0033504,The progression of the floor plate over time from its initial formation until its mature state.,floor plate development,biological_process
70477,GO:0033505,The process in which the anatomical structure of the floor plate is generated and organized.,floor plate morphogenesis,biological_process
70478,GO:0033508,"The anaerobic chemical reactions and pathways resulting in the breakdown of L-glutamate, yielding energy in the form of ATP.",L-glutamate fermentation,biological_process
70479,GO:0033511,"The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.",luteolin biosynthetic process,biological_process
70480,GO:0033520,"The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.",phytol biosynthetic process,biological_process
70481,GO:0033521,"The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.",phytyl diphosphate biosynthetic process,biological_process
70482,GO:0033525,"The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.",sinapate ester biosynthetic process,biological_process
70483,GO:0033528,"A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.",S-methylmethionine cycle,biological_process
70484,GO:0033529,"The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",raffinose biosynthetic process,biological_process
70485,GO:0033530,"The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",raffinose metabolic process,biological_process
70486,GO:0033531,"The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",stachyose metabolic process,biological_process
70487,GO:0033532,"The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",stachyose biosynthetic process,biological_process
70488,GO:0033534,"The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",verbascose biosynthetic process,biological_process
70489,GO:0033536,"The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",ajugose biosynthetic process,biological_process
70490,GO:0033539,"A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).",fatty acid beta-oxidation using acyl-CoA dehydrogenase,biological_process
70491,GO:0033540,"A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).",fatty acid beta-oxidation using acyl-CoA oxidase,biological_process
70492,GO:0033549,Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.,MAP kinase phosphatase activity,molecular_function
70493,GO:0033550,Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.,MAP kinase tyrosine phosphatase activity,molecular_function
70494,GO:0033551,"A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.",monopolin complex,cellular_component
70495,GO:0033552,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.",response to vitamin B3,biological_process
70496,GO:0033553,A region of heterochromatin located at the rDNA repeats in a chromosome.,rDNA heterochromatin,cellular_component
70497,GO:0033554,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",cellular response to stress,biological_process
70498,GO:0033555,"Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",multicellular organismal response to stress,biological_process
70499,GO:0033557,"A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.",Slx1-Slx4 complex,cellular_component
70500,GO:0033558,Catalysis of the reaction: Removal of an acetyl group from a lysine residue in a protein.,protein lysine deacetylase activity,molecular_function
70501,GO:0033559,"The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.",unsaturated fatty acid metabolic process,biological_process
70502,GO:0033560,"Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.",folate reductase activity,molecular_function
70503,GO:0033562,A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.,co-transcriptional gene silencing by RNA interference machinery,biological_process
70504,GO:0033563,The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.,dorsal/ventral axon guidance,biological_process
70505,GO:0033564,The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.,anterior/posterior axon guidance,biological_process
70506,GO:0033565,"A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.",ESCRT-0 complex,cellular_component
70507,GO:0033566,"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.",gamma-tubulin complex localization,biological_process
70508,GO:0033567,"The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.","DNA replication, Okazaki fragment processing",biological_process
70509,GO:0033568,Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.,lactoferrin receptor activity,molecular_function
70510,GO:0033569,Enables the transfer of lactoferrin from one side of a membrane to the other.,lactoferrin transmembrane transporter activity,molecular_function
70511,GO:0033571,"The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lactoferrin transport,biological_process
70512,GO:0033572,"The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",transferrin transport,biological_process
70513,GO:0033573,"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.",high-affinity iron permease complex,cellular_component
70514,GO:0033574,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.",response to testosterone,biological_process
70515,GO:0033583,The portion of the plasma membrane surrounding the rhabdomere.,rhabdomere membrane,cellular_component
70516,GO:0033588,A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA.,elongator holoenzyme complex,cellular_component
70517,GO:0033590,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.",response to cobalamin,biological_process
70518,GO:0033591,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.",response to L-ascorbic acid,biological_process
70519,GO:0033592,An activity that facilitates the formation of a complementary double-stranded RNA molecule.,RNA strand annealing activity,molecular_function
70520,GO:0033593,A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.,BRCA2-MAGE-D1 complex,cellular_component
70521,GO:0033594,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.",response to hydroxyisoflavone,biological_process
70522,GO:0033595,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.",response to genistein,biological_process
70523,GO:0033596,"A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.",TSC1-TSC2 complex,cellular_component
70524,GO:0033597,"A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.",mitotic checkpoint complex,cellular_component
70525,GO:0033598,"The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.",mammary gland epithelial cell proliferation,biological_process
70526,GO:0033599,"Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.",regulation of mammary gland epithelial cell proliferation,biological_process
70527,GO:0033600,"Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.",negative regulation of mammary gland epithelial cell proliferation,biological_process
70528,GO:0033601,Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.,positive regulation of mammary gland epithelial cell proliferation,biological_process
70529,GO:0033602,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.",negative regulation of dopamine secretion,biological_process
70530,GO:0033603,"Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.",positive regulation of dopamine secretion,biological_process
70531,GO:0033604,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.",negative regulation of catecholamine secretion,biological_process
70532,GO:0033605,"Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.",positive regulation of catecholamine secretion,biological_process
70533,GO:0033606,The directed movement of a chemokine receptor within a lipid bilayer.,chemokine receptor transport within lipid bilayer,biological_process
70534,GO:0033607,A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.,SOD1-Bcl-2 complex,cellular_component
70535,GO:0033608,Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.,formyl-CoA transferase activity,molecular_function
70536,GO:0033609,"The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.",oxalate metabolic process,biological_process
70537,GO:0033610,"The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.",oxalate biosynthetic process,biological_process
70538,GO:0033611,"The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.",oxalate catabolic process,biological_process
70539,GO:0033612,Binding to a receptor that possesses protein serine/threonine kinase activity.,receptor serine/threonine kinase binding,molecular_function
70540,GO:0033614,"The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.",chloroplast proton-transporting ATP synthase complex assembly,biological_process
70541,GO:0033615,"The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.",mitochondrial proton-transporting ATP synthase complex assembly,biological_process
70542,GO:0033616,"The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.",plasma membrane proton-transporting ATP synthase complex assembly,biological_process
70543,GO:0033617,"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.",mitochondrial respiratory chain complex IV assembly,biological_process
70544,GO:0033618,"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.",plasma membrane respiratory chain complex IV assembly,biological_process
70545,GO:0033619,The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.,membrane protein proteolysis,biological_process
70546,GO:0033620,A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.,Mei2 nuclear dot complex,cellular_component
70547,GO:0033621,"The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.",nuclear mRNA surveillance of meiosis-specific transcripts,biological_process
70548,GO:0033622,"The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.",integrin activation,biological_process
70549,GO:0033623,"Any process that modulates the frequency, rate, or extent of integrin activation.",regulation of integrin activation,biological_process
70550,GO:0033624,"Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.",negative regulation of integrin activation,biological_process
70551,GO:0033625,"Any process that activates or increases the frequency, rate, or extent of integrin activation.",positive regulation of integrin activation,biological_process
70552,GO:0033626,"Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands.",positive regulation of integrin activation by cell surface receptor linked signal transduction,biological_process
70553,GO:0033627,"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.",cell adhesion mediated by integrin,biological_process
70554,GO:0033628,"Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.",regulation of cell adhesion mediated by integrin,biological_process
70555,GO:0033629,"Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.",negative regulation of cell adhesion mediated by integrin,biological_process
70556,GO:0033630,"Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.",positive regulation of cell adhesion mediated by integrin,biological_process
70557,GO:0033631,"The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.",cell-cell adhesion mediated by integrin,biological_process
70558,GO:0033632,"Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.",regulation of cell-cell adhesion mediated by integrin,biological_process
70559,GO:0033633,"Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.",negative regulation of cell-cell adhesion mediated by integrin,biological_process
70560,GO:0033634,"Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.",positive regulation of cell-cell adhesion mediated by integrin,biological_process
70561,GO:0033635,A process in which a symbiont alters or subverts the response of its host to an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host response to abiotic stimulus,biological_process
70562,GO:0033638,A process in which a symbiont alters or subverts the response of its host to heat acclimation. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host heat acclimation,biological_process
70563,GO:0033643,Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,host cell part,cellular_component
70564,GO:0033644,"Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell membrane,cellular_component
70565,GO:0033645,"A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell endomembrane system,cellular_component
70566,GO:0033646,"Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host intracellular part,cellular_component
70567,GO:0033647,"Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host intracellular organelle,cellular_component
70568,GO:0033648,"Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host intracellular membrane-bounded organelle,cellular_component
70569,GO:0033650,"A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell mitochondrion,cellular_component
70570,GO:0033651,"Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell plastid,cellular_component
70571,GO:0033652,"A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell chloroplast,cellular_component
70572,GO:0033653,"Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell chloroplast part,cellular_component
70573,GO:0033654,"Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell chloroplast thylakoid membrane,cellular_component
70574,GO:0033655,"Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host cell cytoplasm part,cellular_component
70575,GO:0033656,The process in which an organism effects a change that impairs the structure or function of the host chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host chloroplast,biological_process
70576,GO:0033658,The process in which an organism effects a change that impairs the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host chloroplast thylakoid,biological_process
70577,GO:0033659,The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host mitochondrion,biological_process
70578,GO:0033660,A process in which a symbiont inhibits or disrupts the normal execution of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host resistance gene-dependent defense response,biological_process
70579,GO:0033661,A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated defense to host-produced reactive oxygen species,biological_process
70580,GO:0033668,"A process in which a symbiont inhibits or disrupts the normal execution of host apoptosis, leading to a decrease in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host apoptosis,biological_process
70581,GO:0033673,"Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",negative regulation of kinase activity,biological_process
70582,GO:0033674,"Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",positive regulation of kinase activity,biological_process
70583,GO:0033675,"A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.",pericanalicular vesicle,cellular_component
70584,GO:0033677,"Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.",DNA/RNA helicase activity,molecular_function
70585,GO:0033678,"Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.",5'-3' DNA/RNA helicase activity,molecular_function
70586,GO:0033679,"Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.",3'-5' DNA/RNA helicase activity,molecular_function
70587,GO:0033684,"Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.",regulation of luteinizing hormone secretion,biological_process
70588,GO:0033685,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.",negative regulation of luteinizing hormone secretion,biological_process
70589,GO:0033686,"Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.",positive regulation of luteinizing hormone secretion,biological_process
70590,GO:0033687,"The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.",osteoblast proliferation,biological_process
70591,GO:0033688,"Any process that modulates the frequency, rate or extent of osteoblast proliferation.",regulation of osteoblast proliferation,biological_process
70592,GO:0033689,"Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.",negative regulation of osteoblast proliferation,biological_process
70593,GO:0033690,Any process that activates or increases the rate or extent of osteoblast proliferation.,positive regulation of osteoblast proliferation,biological_process
70594,GO:0033691,"Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.",sialic acid binding,molecular_function
70595,GO:0033693,"The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.",neurofilament bundle assembly,biological_process
70596,GO:0033694,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor",molecular_function
70597,GO:0033695,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.,"oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor",molecular_function
70598,GO:0033696,A process that forms a boundary that limits the spreading of heterochromatin along a chromosome.,heterochromatin boundary formation,biological_process
70599,GO:0033698,"A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunit...",Rpd3L complex,cellular_component
70600,GO:0033699,"Catalysis of the reactions: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H+; and: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H+. Nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.",DNA 5'-adenosine monophosphate hydrolase activity,molecular_function
70601,GO:0033700,The directed movement of a phospholipid out of a cell or organelle.,phospholipid efflux,biological_process
70602,GO:0033701,Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.,dTDP-galactose 6-dehydrogenase activity,molecular_function
70603,GO:0033702,"Catalysis of the reaction: (1R,5S)-carveol + NAD+ = (S)-carvone + H+ + NADH.",(+)-trans-carveol dehydrogenase activity,molecular_function
70604,GO:0033703,"Catalysis of the reaction: 3-beta-hydroxy-5-beta-pregnane-20-one + NADP+ = 5-beta-pregnan-3,20-dione + H+ + NADPH.",3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity,molecular_function
70605,GO:0033704,"Catalysis of the reaction: -3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5-alpha-pregnane-3,20-dione + H+ + NADPH.",3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity,molecular_function
70606,GO:0033705,Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.,GDP-4-dehydro-6-deoxy-D-mannose reductase activity,molecular_function
70607,GO:0033707,Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.,3''-deamino-3''-oxonicotianamine reductase activity,molecular_function
70608,GO:0033708,"Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.",isocitrate-homoisocitrate dehydrogenase activity,molecular_function
70609,GO:0033709,Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. Can also produce D-ribulose.,D-arabinitol dehydrogenase (NADP+) activity,molecular_function
70610,GO:0033711,Catalysis of the reaction: 4-phospho-D-erythronate + NAD+ = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H+ + NADH.,4-phosphoerythronate dehydrogenase activity,molecular_function
70611,GO:0033712,"Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.","1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity",molecular_function
70612,GO:0033713,Catalysis of the reaction: choline + O2 = betaine aldehyde + H2O2.,choline:oxygen 1-oxidoreductase activity,molecular_function
70613,GO:0033714,Catalysis of the reaction: secondary alcohol + O2 = H2O2 + ketone.,secondary-alcohol oxidase activity,molecular_function
70614,GO:0033715,"Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.",nucleoside oxidase activity,molecular_function
70615,GO:0033716,Catalysis of the reaction: adenosine + 2 O2 + H2O = 9-riburonosyladenine + 2 H2O2 + H+.,nucleoside oxidase (hydrogen peroxide-forming) activity,molecular_function
70616,GO:0033717,Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.,gluconate 2-dehydrogenase (acceptor) activity,molecular_function
70617,GO:0033718,"Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.",pyranose dehydrogenase (acceptor) activity,molecular_function
70618,GO:0033719,Catalysis of the reaction: a (2R)-hydroxycarboxylate + acceptor = a 2-oxocarboxylate + reduced acceptor.,(2R)-oxo-acid reductase activity,molecular_function
70619,GO:0033720,Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.,(S)-mandelate dehydrogenase activity,molecular_function
70620,GO:0033721,Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.,aldehyde dehydrogenase (NADP+) activity,molecular_function
70621,GO:0033722,Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.,malonate-semialdehyde dehydrogenase [NAD(P)+] activity,molecular_function
70622,GO:0033723,Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.,fluoroacetaldehyde dehydrogenase (NAD+) activity,molecular_function
70623,GO:0033726,Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.,aldehyde ferredoxin oxidoreductase activity,molecular_function
70624,GO:0033727,Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.,aldehyde dehydrogenase (FAD-independent) activity,molecular_function
70625,GO:0033728,"Catalysis of the reaction: protochlorophyllide a + NADP+ = 3,8-divinyl protochlorophyllide a + NADPH + H+, and chlorophyllide a + NADP+ = 3,8-divinyl chlorophyllide a + NADPH + H+.","3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activity",molecular_function
70626,GO:0033729,Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.,anthocyanidin reductase activity,molecular_function
70627,GO:0033730,Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.,arogenate dehydrogenase (NADP+) activity,molecular_function
70628,GO:0033731,Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.,arogenate dehydrogenase [NAD(P)+] activity,molecular_function
70629,GO:0033732,"Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 2 H2O + 2 H2O2 + H+ + pyrroloquinoline quinone.",pyrroloquinoline-quinone synthase activity,molecular_function
70630,GO:0033734,Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.,(R)-benzylsuccinyl-CoA dehydrogenase activity,molecular_function
70631,GO:0033735,Catalysis of the reaction: Catalysis of the reaction: L-aspartate + NAD(P)+ + H2O = oxaloacetate + NH4+ + NADPH + H+.,L-aspartate dehydrogenase [NAD(P)+] activity,molecular_function
70632,GO:0033736,Catalysis of the reaction: H2O + L-lysine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + NH4+.,L-lysine 6-oxidase activity,molecular_function
70633,GO:0033738,"Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.",methylenetetrahydrofolate reductase (ferredoxin) activity,molecular_function
70634,GO:0033739,Catalysis of the reaction: 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 2 NADPH + 3 H+.,preQ1 synthase activity,molecular_function
70635,GO:0033740,Catalysis of the reaction: hydroxylamine + 3 Fe(III)-[cytochrome c] = nitric oxide + 3 Fe(II)-[cytochrome c] + 3 H+.,hydroxylamine oxidoreductase activity,molecular_function
70636,GO:0033741,Catalysis of the reaction: AMP + glutathione disulfide + H+ + sulfite = 5'-adenylyl sulfate + 2 glutathione.,adenylyl-sulfate reductase (glutathione) activity,molecular_function
70637,GO:0033743,Catalysis of the reaction: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol.,peptide-methionine (R)-S-oxide reductase activity,molecular_function
70638,GO:0033744,Catalysis of the reaction: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol.,L-methionine (S)-S-oxide reductase activity,molecular_function
70639,GO:0033745,Catalysis of the reaction: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol.,L-methionine (R)-S-oxide reductase activity,molecular_function
70640,GO:0033746,Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3R2 demethylase activity,molecular_function
70641,GO:0033748,Catalysis of the reaction: H2 + A = AH2.,hydrogenase (acceptor) activity,molecular_function
70642,GO:0033749,Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H4R3 demethylase activity,molecular_function
70643,GO:0033750,"A process in which a ribosome is transported to, and/or maintained in, a specific location.",ribosome localization,biological_process
70644,GO:0033752,"Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.",acetylacetone-cleaving enzyme activity,molecular_function
70645,GO:0033754,Catalysis of the reaction: D-tryptophan + O2 = N-formyl-D-kynurenine.,"indoleamine 2,3-dioxygenase activity",molecular_function
70646,GO:0033755,Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.,sulfur oxygenase/reductase activity,molecular_function
70647,GO:0033756,Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.,Oplophorus-luciferin 2-monooxygenase activity,molecular_function
70648,GO:0033757,Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.,glucoside 3-dehydrogenase activity,molecular_function
70649,GO:0033758,Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.,clavaminate synthase activity,molecular_function
70650,GO:0033759,Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.,flavone synthase activity,molecular_function
70651,GO:0033760,Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + H+ + mugineate + succinate.,2'-deoxymugineic-acid 2'-dioxygenase activity,molecular_function
70652,GO:0033761,Catalysis of the reaction: mugineate + 2-oxoglutarate + O2 = 3-epihydroxymugineate + CO2 + H+ + succinate. Also converts 2'-deoxymugineate to 3-epihydroxy-2'-deoxymugineate.,mugineic-acid 3-dioxygenase activity,molecular_function
70653,GO:0033762,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.",response to glucagon,biological_process
70654,GO:0033763,Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.,proline 3-hydroxylase activity,molecular_function
70655,GO:0033764,"Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.","steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",molecular_function
70656,GO:0033765,"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.","steroid dehydrogenase activity, acting on the CH-CH group of donors",molecular_function
70657,GO:0033766,"Catalysis of the reaction: H+ + NADH + O2 + quinolin-2-ol = H2O + NAD+ + quinoline-2,8-diol.",2-hydroxyquinoline 8-monooxygenase activity,molecular_function
70658,GO:0033767,Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.,4-hydroxyacetophenone monooxygenase activity,molecular_function
70659,GO:0033768,A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.,SUMO-targeted ubiquitin ligase complex,cellular_component
70660,GO:0033769,"Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin II or glyceollin III + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin I + NADP+ + 2 H2O.",glyceollin synthase activity,molecular_function
70661,GO:0033770,"Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase].",2-hydroxyisoflavanone synthase activity,molecular_function
70662,GO:0033771,Catalysis of the reaction: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,flavanone 2-hydroxylase activity,molecular_function
70663,GO:0033772,"Catalysis of the reaction: a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = a 3',5'-dihydroxyflavanone + 2 H+ + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase].","flavonoid 3',5'-hydroxylase activity",molecular_function
70664,GO:0033773,Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].,isoflavone 2'-hydroxylase activity,molecular_function
70665,GO:0033774,A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.,basal labyrinth,cellular_component
70666,GO:0033775,Catalysis of the reaction: 10-deoxysarpagine + H+ + NADPH + O2 = H2O + NADP+ + sarpagine.,deoxysarpagine hydroxylase activity,molecular_function
70667,GO:0033776,Catalysis of the reaction: H+ + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP+.,phenylacetone monooxygenase activity,molecular_function
70668,GO:0033777,Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.,lithocholate 6beta-hydroxylase activity,molecular_function
70669,GO:0033780,"Catalysis of the reaction: taurochenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] +  = taurohyocholate H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate.",taurochenodeoxycholate 6alpha-hydroxylase activity,molecular_function
70670,GO:0033781,Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.,cholesterol 24-hydroxylase activity,molecular_function
70671,GO:0033782,Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].,24S-hydroxycholesterol 7-alpha-hydroxylase activity,molecular_function
70672,GO:0033783,"Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol.",25-hydroxycholesterol 7-alpha-hydroxylase activity,molecular_function
70673,GO:0033784,Catalysis of the reaction: H+ + NADPH + O2 + senecionine = H2O + NADP+ + senecionine N-oxide.,senecionine N-oxygenase activity,molecular_function
70674,GO:0033785,"Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.",heptose 7-phosphate kinase activity,molecular_function
70675,GO:0033786,Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.,heptose-1-phosphate adenylyltransferase activity,molecular_function
70676,GO:0033787,Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP+ = cyanocob(III)alamin + H+ + NADPH.,cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity,molecular_function
70677,GO:0033788,"Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.",leucoanthocyanidin reductase activity,molecular_function
70678,GO:0033789,"Catalysis of the reaction: 2 1,4-benzoquinone + H2O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.",phenylacetyl-CoA dehydrogenase activity,molecular_function
70679,GO:0033791,"Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.","3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity",molecular_function
70680,GO:0033792,Catalysis of the reactions: a 3alpha-hydroxy bile acid CoA + NAD+ = a 3-oxo bile acid CoA + H+ + NADH.,3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity,molecular_function
70681,GO:0033793,"Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = aureusidin 6-O-beta-glucoside + H2O, 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H+ + O2 = 2 aureusidin 6-O-beta-glucoside + 2 H2O, and 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = bracteatin 6-O-beta-glucoside + H2O. This activity consists of two separate chemical transformations: 3-hydroxylation and oxidative cyclization (2',-dehydrogenation).",aureusidin synthase activity,molecular_function
70682,GO:0033794,Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.,sarcosine reductase activity,molecular_function
70683,GO:0033795,Catalysis of the reaction: [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H+ + phosphate.,betaine reductase activity,molecular_function
70684,GO:0033796,"Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide, H2 + n sulfur = H+ + hydrogen sulfide + (n-1) sulfur.",sulfur reductase activity,molecular_function
70685,GO:0033797,Catalysis of the reaction: 2 e(-) + 2 H+ + selenate = H2O + selenite.,selenate reductase activity,molecular_function
70686,GO:0033798,"Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + acceptor-H2.",thyroxine 5-deiodinase activity,molecular_function
70687,GO:0033799,Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.,myricetin 3'-O-methyltransferase activity,molecular_function
70688,GO:0033800,Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.,isoflavone 7-O-methyltransferase activity,molecular_function
70689,GO:0033801,Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.,vitexin 2''-O-rhamnoside 7-O-methyltransferase activity,molecular_function
70690,GO:0033802,Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H+.,isoliquiritigenin 2'-O-methyltransferase activity,molecular_function
70691,GO:0033803,Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H+ + kaempferide.,kaempferol 4'-O-methyltransferase activity,molecular_function
70692,GO:0033806,Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.,fluorothreonine transaldolase activity,molecular_function
70693,GO:0033808,Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.,6'-deoxychalcone synthase activity,molecular_function
70694,GO:0033809,Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).,anthocyanin 6''-O-malonyltransferase activity,molecular_function
70695,GO:0033810,Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.,anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity,molecular_function
70696,GO:0033811,Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].,flavonol-3-O-triglucoside O-coumaroyltransferase activity,molecular_function
70697,GO:0033812,Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.,3-oxoadipyl-CoA thiolase activity,molecular_function
70698,GO:0033813,Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.,deacetylcephalosporin-C acetyltransferase activity,molecular_function
70699,GO:0033814,"Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.",propanoyl-CoA C-acyltransferase activity,molecular_function
70700,GO:0033815,"Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.",biphenyl synthase activity,molecular_function
70701,GO:0033816,"Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H+.",diaminobutyrate acetyltransferase activity,molecular_function
70702,GO:0033818,Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.,beta-ketoacyl-acyl-carrier-protein synthase III activity,molecular_function
70703,GO:0033819,Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].,lipoyl(octanoyl) transferase activity,molecular_function
70704,GO:0033820,Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.,DNA alpha-glucosyltransferase activity,molecular_function
70705,GO:0033821,Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.,DNA beta-glucosyltransferase activity,molecular_function
70706,GO:0033822,Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.,glucosyl-DNA beta-glucosyltransferase activity,molecular_function
70707,GO:0033823,"Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.",procollagen glucosyltransferase activity,molecular_function
70708,GO:0033825,"Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.",oligosaccharide 4-alpha-D-glucosyltransferase activity,molecular_function
70709,GO:0033826,"Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.",xyloglucan 4-glucosyltransferase activity,molecular_function
70710,GO:0033827,"Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.","high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity",molecular_function
70711,GO:0033828,Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H+.,glucosylglycerol-phosphate synthase activity,molecular_function
70712,GO:0033829,Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.,O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity,molecular_function
70713,GO:0033830,Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.,Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity,molecular_function
70714,GO:0033831,Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.,kojibiose phosphorylase activity,molecular_function
70715,GO:0033832,"Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.","alpha,alpha-trehalose phosphorylase (configuration-retaining) activity",molecular_function
70716,GO:0033833,"Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.",hydroxymethylfurfural reductase (NADH) activity,molecular_function
70717,GO:0033834,Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.,kaempferol 3-O-galactosyltransferase activity,molecular_function
70718,GO:0033835,Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].,flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity,molecular_function
70719,GO:0033836,Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.,flavonol 7-O-beta-glucosyltransferase activity,molecular_function
70720,GO:0033837,Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.,anthocyanin 3'-O-beta-glucosyltransferase activity,molecular_function
70721,GO:0033838,Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.,flavonol-3-O-glucoside glucosyltransferase activity,molecular_function
70722,GO:0033839,Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.,flavonol-3-O-glycoside glucosyltransferase activity,molecular_function
70723,GO:0033840,"Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + an NDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + a ribonucleoside 5'-diphosphate + H+, where NDP is ADP or UDP.","alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity",molecular_function
70724,GO:0033841,Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).,6G-fructosyltransferase activity,molecular_function
70725,GO:0033842,Catalysis of the reaction: an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H+.,N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity,molecular_function
70726,GO:0033843,"Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.",xyloglucan 6-xylosyltransferase activity,molecular_function
70727,GO:0033844,"Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.",galactose-6-sulfurylase activity,molecular_function
70728,GO:0033845,"Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.",hydroxymethylfurfural reductase (NADPH) activity,molecular_function
70729,GO:0033846,Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.,adenosyl-fluoride synthase activity,molecular_function
70730,GO:0033847,Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.,O-phosphoserine sulfhydrylase activity,molecular_function
70731,GO:0033848,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H+ + phosphate.,N2-(2-carboxyethyl)arginine synthase activity,molecular_function
70732,GO:0033849,"Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.",chrysanthemyl diphosphate synthase activity,molecular_function
70733,GO:0033850,"Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.",Z-farnesyl diphosphate synthase activity,molecular_function
70734,GO:0033851,Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.,lavandulyl diphosphate synthase activity,molecular_function
70735,GO:0033852,"Catalysis of the reaction: 3,3',5-triiodo-L-thyronine + 2-oxoglutarate = 3,5,3'-triiodothyropyruvate + L-glutamate.",thyroid-hormone:2-oxoglutarate transaminase activity,molecular_function
70736,GO:0033853,Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate.,L-aspartate:prephenate transaminase activity,molecular_function
70737,GO:0033854,Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.,L-glutamate:prephenate transaminase activity,molecular_function
70738,GO:0033855,Catalysis of the reaction: nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine + L-glutamate.,nicotianamine:2-oxoglutarate transaminase activity,molecular_function
70739,GO:0033856,Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H2O + H+ + phosphate + pyridoxine 5'-phosphate.,pyridoxine 5'-phosphate synthase activity,molecular_function
70740,GO:0033857,Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.,5-diphosphoinositol pentakisphosphate 1-kinase activity,molecular_function
70741,GO:0033858,Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.,N-acetylgalactosamine kinase activity,molecular_function
70742,GO:0033859,"The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.",furaldehyde metabolic process,biological_process
70743,GO:0033862,Catalysis of the reaction: ATP + UMP = ADP + UDP.,UMP kinase activity,molecular_function
70744,GO:0033863,"Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H+.","ribose 1,5-bisphosphate phosphokinase activity",molecular_function
70745,GO:0033864,Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.,positive regulation of NAD(P)H oxidase activity,biological_process
70746,GO:0033865,"The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",nucleoside bisphosphate metabolic process,biological_process
70747,GO:0033866,"The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",nucleoside bisphosphate biosynthetic process,biological_process
70748,GO:0033867,Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.,Fas-activated serine/threonine kinase activity,molecular_function
70749,GO:0033869,"The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",nucleoside bisphosphate catabolic process,biological_process
70750,GO:0033870,"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.",thiol sulfotransferase activity,molecular_function
70751,GO:0033873,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H+.",petromyzonol sulfotransferase activity,molecular_function
70752,GO:0033874,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H+.",scymnol sulfotransferase activity,molecular_function
70753,GO:0033875,"The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",ribonucleoside bisphosphate metabolic process,biological_process
70754,GO:0033876,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H+.",glycochenodeoxycholate sulfotransferase activity,molecular_function
70755,GO:0033877,Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.,succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity,molecular_function
70756,GO:0033879,"Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.",acetylajmaline esterase activity,molecular_function
70757,GO:0033880,Catalysis of the reaction: H2O + phenylglyoxylyl-CoA = CoA + H+ + phenylglyoxylate.,phenylacetyl-CoA hydrolase activity,molecular_function
70758,GO:0033881,Catalysis of the reaction: deoxycholoyl-CoA + cholate = deoxycholate + choloyl-CoA.,bile-acid-CoA transferase activity,molecular_function
70759,GO:0033882,Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.,choloyl-CoA hydrolase activity,molecular_function
70760,GO:0033883,Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.,pyridoxal phosphatase activity,molecular_function
70761,GO:0033885,"Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.",10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,molecular_function
70762,GO:0033886,Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.,cellulose-polysulfatase activity,molecular_function
70763,GO:0033887,Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.,chondro-4-sulfatase activity,molecular_function
70764,GO:0033888,Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.,chondro-6-sulfatase activity,molecular_function
70765,GO:0033889,Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.,N-sulfoglucosamine-3-sulfatase activity,molecular_function
70766,GO:0033890,Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.,ribonuclease D activity,molecular_function
70767,GO:0033891,"Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.",CC-preferring endodeoxyribonuclease activity,molecular_function
70768,GO:0033892,Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate.,deoxyribonuclease (pyrimidine dimer) activity,molecular_function
70769,GO:0033893,Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.,ribonuclease IV activity,molecular_function
70770,GO:0033894,"Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.",ribonuclease P4 activity,molecular_function
70771,GO:0033895,Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.,ribonuclease [poly-(U)-specific] activity,molecular_function
70772,GO:0033896,Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.,ribonuclease IX activity,molecular_function
70773,GO:0033897,"Catalysis of the reaction: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H+. This reaction is a two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.",ribonuclease T2 activity,molecular_function
70774,GO:0033899,"Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.",ribonuclease U2 activity,molecular_function
70775,GO:0033900,"Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.",ribonuclease F activity,molecular_function
70776,GO:0033901,"Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.",ribonuclease V activity,molecular_function
70777,GO:0033902,Catalysis of the reaction: a 28S rRNA containing guanosine-adenosine pair + H2O = an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment].,rRNA endonuclease activity,molecular_function
70778,GO:0033904,"Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.",dextranase activity,molecular_function
70779,GO:0033905,Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.,"xylan endo-1,3-beta-xylosidase activity",molecular_function
70780,GO:0033906,"Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.",hyaluronoglucuronidase activity,molecular_function
70781,GO:0033907,Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.,beta-D-fucosidase activity,molecular_function
70782,GO:0033908,"Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.",beta-L-rhamnosidase activity,molecular_function
70783,GO:0033909,"Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.",fucoidanase activity,molecular_function
70784,GO:0033910,"Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.","glucan 1,4-alpha-maltotetraohydrolase activity",molecular_function
70785,GO:0033911,"Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.",mycodextranase activity,molecular_function
70786,GO:0033912,"Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.","2,6-beta-fructan 6-levanbiohydrolase activity",molecular_function
70787,GO:0033913,Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.,"glucan endo-1,2-beta-glucosidase activity",molecular_function
70788,GO:0033914,Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.,"xylan 1,3-beta-xylosidase activity",molecular_function
70789,GO:0033915,"Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.","mannan 1,2-(1,3)-alpha-mannosidase activity",molecular_function
70790,GO:0033916,"Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.",beta-agarase activity,molecular_function
70791,GO:0033917,"Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.",exo-poly-alpha-galacturonosidase activity,molecular_function
70792,GO:0033918,"Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.",kappa-carrageenase activity,molecular_function
70793,GO:0033919,"Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.","glucan 1,3-alpha-glucosidase activity",molecular_function
70794,GO:0033920,Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.,6-phospho-beta-galactosidase activity,molecular_function
70795,GO:0033921,Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.,"capsular-polysaccharide endo-1,3-alpha-galactosidase activity",molecular_function
70796,GO:0033922,"Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.",peptidoglycan beta-N-acetylmuramidase activity,molecular_function
70797,GO:0033923,"Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.","glucan 1,6-alpha-isomaltosidase activity",molecular_function
70798,GO:0033924,"Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.","dextran 1,6-alpha-isomaltotriosidase activity",molecular_function
70799,GO:0033925,"Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.",mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity,molecular_function
70800,GO:0033926,Catalysis of the reactions : D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine and D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-threonyl + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-threonyl.,endo-alpha-N-acetylgalactosaminidase activity,molecular_function
70801,GO:0033927,"Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.","glucan 1,4-alpha-maltohexaosidase activity",molecular_function
70802,GO:0033928,"Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.","mannan 1,4-mannobiosidase activity",molecular_function
70803,GO:0033929,Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.,"blood-group-substance endo-1,4-beta-galactosidase activity",molecular_function
70804,GO:0033930,Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.,"keratan-sulfate endo-1,4-beta-galactosidase activity",molecular_function
70805,GO:0033931,Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).,endogalactosaminidase activity,molecular_function
70806,GO:0033932,Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.,"1,3-alpha-L-fucosidase activity",molecular_function
70807,GO:0033933,"Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.","branched-dextran exo-1,2-alpha-glucosidase activity",molecular_function
70808,GO:0033934,"Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.","glucan 1,4-alpha-maltotriohydrolase activity",molecular_function
70809,GO:0033935,"Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.",oligoxyloglucan beta-glycosidase activity,molecular_function
70810,GO:0033936,Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.,polymannuronate hydrolase activity,molecular_function
70811,GO:0033937,Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.,3-deoxy-2-octulosonidase activity,molecular_function
70812,GO:0033938,Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.,"1,6-alpha-L-fucosidase activity",molecular_function
70813,GO:0033939,Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.,"xylan alpha-1,2-glucuronosidase activity",molecular_function
70814,GO:0033940,Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.,"glucuronoarabinoxylan endo-1,4-beta-xylanase activity",molecular_function
70815,GO:0033941,"Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.","mannan exo-1,2-1,6-alpha-mannosidase activity",molecular_function
70816,GO:0033942,Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.,4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity,molecular_function
70817,GO:0033943,"Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.","galactan 1,3-beta-galactosidase activity",molecular_function
70818,GO:0033944,"Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.",beta-galactofuranosidase activity,molecular_function
70819,GO:0033945,"Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.",oligoxyloglucan reducing-end-specific cellobiohydrolase activity,molecular_function
70820,GO:0033946,Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.,"xyloglucan-specific endo-beta-1,4-glucanase activity",molecular_function
70821,GO:0033947,Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.,mannosylglycoprotein endo-beta-mannosidase activity,molecular_function
70822,GO:0033948,"Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.","fructan beta-(2,1)-fructosidase activity",molecular_function
70823,GO:0033949,"Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.","fructan beta-(2,6)-fructosidase activity",molecular_function
70824,GO:0033950,"Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.","xyloglucan-specific exo-beta-1,4-glucanase activity",molecular_function
70825,GO:0033951,"Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.",oligosaccharide reducing-end xylanase activity,molecular_function
70826,GO:0033952,"Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.",iota-carrageenase activity,molecular_function
70827,GO:0033953,"Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.",alpha-agarase activity,molecular_function
70828,GO:0033954,"Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.",alpha-neoagaro-oligosaccharide hydrolase activity,molecular_function
70829,GO:0033956,Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.,beta-apiosyl-beta-glucosidase activity,molecular_function
70830,GO:0033957,"Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.",lambda-carrageenase activity,molecular_function
70831,GO:0033958,"Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine.",DNA-deoxyinosine glycosylase activity,molecular_function
70832,GO:0033959,Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.,deoxyribodipyrimidine endonucleosidase activity,molecular_function
70833,GO:0033960,Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.,N-methyl nucleosidase activity,molecular_function
70834,GO:0033961,"Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.",cis-stilbene-oxide hydrolase activity,molecular_function
70835,GO:0033962,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.",P-body assembly,biological_process
70836,GO:0033963,"Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.","cholesterol-5,6-oxide hydrolase activity",molecular_function
70837,GO:0033964,"Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.",glycosphingolipid deacylase activity,molecular_function
70838,GO:0033965,"Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.",aculeacin-A deacylase activity,molecular_function
70839,GO:0033966,Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.,N-substituted formamide deformylase activity,molecular_function
70840,GO:0033967,The chemical reactions and pathways involving box C/D type small nucleolar RNA.,box C/D sno(s)RNA metabolic process,biological_process
70841,GO:0033968,Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.,glutaryl-7-aminocephalosporanic-acid acylase activity,molecular_function
70842,GO:0033969,Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate.,gamma-glutamyl-gamma-aminobutyrate hydrolase activity,molecular_function
70843,GO:0033970,Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H2O = H+ + malonate + urea.,N-malonylurea hydrolase activity,molecular_function
70844,GO:0033971,"Catalysis of the reaction: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+.",hydroxyisourate hydrolase activity,molecular_function
70845,GO:0033972,Catalysis of the reaction: amidinoproclavaminate + H2O = proclavaminate + urea.,proclavaminate amidinohydrolase activity,molecular_function
70846,GO:0033973,Catalysis of the reaction: dCTP + 2 H2O = diphosphate + dUMP + H+ + NH4.,dCTP deaminase (dUMP-forming) activity,molecular_function
70847,GO:0033974,Catalysis of the hydrolysis of mixed phospho-anhydride bonds.,nucleoside phosphoacylhydrolase activity,molecular_function
70848,GO:0033975,Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.,(R)-2-haloacid dehalogenase activity,molecular_function
70849,GO:0033976,"Catalysis of the reactions: an (S)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H+, and an (R)-2-haloacid + H2O = a (2S)-2-hydroxycarboxylate + a halide anion + H+.",2-haloacid dehalogenase (configuration-inverting) activity,molecular_function
70850,GO:0033977,"Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.",2-haloacid dehalogenase (configuration-retaining) activity,molecular_function
70851,GO:0033978,Catalysis of the reaction: 3-phosphonopyruvate + H2O = H+ + phosphate + pyruvate.,phosphonopyruvate hydrolase activity,molecular_function
70852,GO:0033979,The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.,box H/ACA sno(s)RNA metabolic process,biological_process
70853,GO:0033980,Catalysis of the reaction: 3-phosphonopyruvate + 2 H+ = CO2 + phosphonoacetaldehyde.,phosphonopyruvate decarboxylase activity,molecular_function
70854,GO:0033981,"Catalysis of the reaction: D-dopachrome + H+ = 5,6-dihydroxyindole + CO2.",D-dopachrome decarboxylase activity,molecular_function
70855,GO:0033982,Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2.,3-dehydro-L-gulonate-6-phosphate decarboxylase activity,molecular_function
70856,GO:0033983,"Catalysis of the reaction: L-2,4-diaminobutyrate + H+ = 1,3-diaminopropane + CO2.",diaminobutyrate decarboxylase activity,molecular_function
70857,GO:0033984,"Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.",indole-3-glycerol-phosphate lyase activity,molecular_function
70858,GO:0033985,The volume enclosed by the membranes of an acidocalcisome.,acidocalcisome lumen,cellular_component
70859,GO:0033986,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.",response to methanol,biological_process
70860,GO:0033987,"Catalysis of the reactions: (2R,3S)-2,4',7-trihydroxyisoflavanone = daidzein + H+ + H2O, and 2-hydroxy-2,3-dihydrogenistein = genistein + H+ + H2O.",2-hydroxyisoflavanone dehydratase activity,molecular_function
70861,GO:0033988,"Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O.",bile-acid 7alpha-dehydratase activity,molecular_function
70862,GO:0033989,"Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.","3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity",molecular_function
70863,GO:0033990,"Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H2O.",ectoine synthase activity,molecular_function
70864,GO:0033991,"Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.",aldos-2-ulose dehydratase activity,molecular_function
70865,GO:0033992,"Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.","1,5-anhydro-D-fructose dehydratase activity",molecular_function
70866,GO:0033993,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.",response to lipid,biological_process
70867,GO:0033994,Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.,glucuronan lyase activity,molecular_function
70868,GO:0033995,"Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.",anhydrosialidase activity,molecular_function
70869,GO:0033996,"Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.",levan fructotransferase (DFA-IV-forming) activity,molecular_function
70870,GO:0033997,"Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.",inulin fructotransferase (DFA-I-forming) activity,molecular_function
70871,GO:0033998,"Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.",inulin fructotransferase (DFA-III-forming) activity,molecular_function
70872,GO:0033999,"Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.",chondroitin B lyase activity,molecular_function
70873,GO:0034000,"Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.",chondroitin-sulfate-ABC endolyase activity,molecular_function
70874,GO:0034001,Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.,chondroitin-sulfate-ABC exolyase activity,molecular_function
70875,GO:0034002,Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate.,(R)-limonene synthase activity,molecular_function
70876,GO:0034003,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.",vetispiradiene synthase activity,molecular_function
70877,GO:0034004,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.",germacradienol synthase activity,molecular_function
70878,GO:0034005,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.",germacrene-A synthase activity,molecular_function
70879,GO:0034006,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.","amorpha-4,11-diene synthase activity",molecular_function
70880,GO:0034007,Catalysis of the reaction: geranyl diphosphate + H2O = (S)-linalool + diphosphate.,S-linalool synthase activity,molecular_function
70881,GO:0034008,Catalysis of the reaction: geranyl diphosphate + H2O = (R)-linalool + diphosphate.,R-linalool synthase activity,molecular_function
70882,GO:0034009,Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.,isoprene synthase activity,molecular_function
70883,GO:0034010,Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.,sulfolactate sulfo-lyase activity,molecular_function
70884,GO:0034011,Catalysis of the reaction: L-cysteate + H2O = NH4 + pyruvate + sulfite.,L-cysteate sulfo-lyase activity,molecular_function
70885,GO:0034012,"Catalysis of the reaction: FAD = AMP + H+ + riboflavin cyclic-4',5'-phosphate.",FAD-AMP lyase (cyclizing) activity,molecular_function
70886,GO:0034013,Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.,aliphatic aldoxime dehydratase activity,molecular_function
70887,GO:0034014,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.",response to triglyceride,biological_process
70888,GO:0034015,Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.,L-ribulose-5-phosphate 3-epimerase activity,molecular_function
70889,GO:0034016,"Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.",polyenoic fatty acid isomerase activity,molecular_function
70890,GO:0034017,Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].,trans-2-decenoyl-acyl-carrier-protein isomerase activity,molecular_function
70891,GO:0034018,"Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.",ascopyrone tautomerase activity,molecular_function
70892,GO:0034020,Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.,neoxanthin synthase activity,molecular_function
70893,GO:0034021,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.",response to silicon dioxide,biological_process
70894,GO:0034022,Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.,3-(hydroxyamino)phenol mutase activity,molecular_function
70895,GO:0034023,Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.,5-(carboxyamino)imidazole ribonucleotide mutase activity,molecular_function
70896,GO:0034024,Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H+ + phosphate.,glutamate-putrescine ligase activity,molecular_function
70897,GO:0034025,Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.,D-aspartate ligase activity,molecular_function
70898,GO:0034026,Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.,L-amino-acid alpha-ligase activity,molecular_function
70899,GO:0034027,Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H+.,(carboxyethyl)arginine beta-lactam-synthase activity,molecular_function
70900,GO:0034028,Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H+ + phosphate.,5-(carboxyamino)imidazole ribonucleotide synthase activity,molecular_function
70901,GO:0034029,Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H+ + oxalosuccinate + phosphate.,2-oxoglutarate carboxylase activity,molecular_function
70902,GO:0034030,"The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",ribonucleoside bisphosphate biosynthetic process,biological_process
70903,GO:0034031,"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",ribonucleoside bisphosphate catabolic process,biological_process
70904,GO:0034032,"The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine nucleoside bisphosphate metabolic process,biological_process
70905,GO:0034033,"The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine nucleoside bisphosphate biosynthetic process,biological_process
70906,GO:0034034,"The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine nucleoside bisphosphate catabolic process,biological_process
70907,GO:0034035,"The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine ribonucleoside bisphosphate metabolic process,biological_process
70908,GO:0034036,"The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine ribonucleoside bisphosphate biosynthetic process,biological_process
70909,GO:0034037,"The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.",purine ribonucleoside bisphosphate catabolic process,biological_process
70910,GO:0034038,"Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enz...",deoxyhypusine synthase activity,molecular_function
70911,GO:0034039,"Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.","8-oxo-7,8-dihydroguanine DNA N-glycosylase activity",molecular_function
70912,GO:0034040,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).,ATPase-coupled lipid transmembrane transporter activity,molecular_function
70913,GO:0034041,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).,ABC-type sterol transporter activity,molecular_function
70914,GO:0034042,Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.,5-formyluracil DNA N-glycosylase activity,molecular_function
70915,GO:0034043,Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.,5-hydroxymethyluracil DNA N-glycosylase activity,molecular_function
70916,GO:0034044,A protein complex that acts as a selective cargo adaptor mediating the selective transport of specific membrane proteins from the trans-Golgi network (TGN) to the plasma membrane.,exomer complex,cellular_component
70917,GO:0034045,A cellular membrane associated with the phagophore assembly site.,phagophore assembly site membrane,cellular_component
70918,GO:0034046,Binding to a sequence of guanine residues in an RNA molecule.,poly(G) binding,molecular_function
70919,GO:0034050,"Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.",symbiont-induced defense-related programmed cell death,biological_process
70920,GO:0034051,"Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.",negative regulation of plant-type hypersensitive response,biological_process
70921,GO:0034052,"Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.",positive regulation of plant-type hypersensitive response,biological_process
70922,GO:0034055,A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated activation of host programmed cell death by symbiont,biological_process
70923,GO:0034056,"Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.",estrogen response element binding,molecular_function
70924,GO:0034057,Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.,RNA strand-exchange activity,molecular_function
70925,GO:0034058,The homotypic fusion of endocytic vesicles to form or add to an early endosome.,endosomal vesicle fusion,biological_process
70926,GO:0034059,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.",response to anoxia,biological_process
70927,GO:0034060,The space enclosed by the double membrane of a cyanelle.,cyanelle stroma,cellular_component
70928,GO:0034061,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).,DNA polymerase activity,molecular_function
70929,GO:0034062,"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.",5'-3' RNA polymerase activity,molecular_function
70930,GO:0034063,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic stress granule.",cytoplasmic stress granule assembly,biological_process
70931,GO:0034064,A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.,Tor2-Mei2-Ste11 complex,cellular_component
70932,GO:0034066,"A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.",Ric1-Rgp1 guanyl-nucleotide exchange factor complex,cellular_component
70933,GO:0034067,"A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.",protein localization to Golgi apparatus,biological_process
70934,GO:0034068,Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.,aminoglycoside nucleotidyltransferase activity,molecular_function
70935,GO:0034069,Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.,aminoglycoside N-acetyltransferase activity,molecular_function
70936,GO:0034071,Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.,aminoglycoside phosphotransferase activity,molecular_function
70937,GO:0034072,Catalysis of the reaction: squalene = triterpene.,squalene cyclase activity,molecular_function
70938,GO:0034073,Catalysis of the reaction: tetrahymanol = squalene + H2O.,tetrahymanol synthase activity,molecular_function
70939,GO:0034074,"Catalysis of the reaction: (S)-2,3-epoxysqualene = marneral.",marneral synthase activity,molecular_function
70940,GO:0034075,"Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).",arabidiol synthase activity,molecular_function
70941,GO:0034076,"Catalysis of the reaction: (S)-2,3-epoxysqualene = cucurbitadienol.",cucurbitadienol synthase activity,molecular_function
70942,GO:0034077,"The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.",butanediol metabolic process,biological_process
70943,GO:0034078,"The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.",butanediol catabolic process,biological_process
70944,GO:0034079,"The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol.",butanediol biosynthetic process,biological_process
70945,GO:0034080,"The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.",CENP-A containing chromatin assembly,biological_process
70946,GO:0034081,"A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.",polyketide synthase complex,cellular_component
70947,GO:0034082,"A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.",type II polyketide synthase complex,cellular_component
70948,GO:0034083,A polyketide synthase complex that consists of two identical ketosynthase polypeptides.,type III polyketide synthase complex,cellular_component
70949,GO:0034084,Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.,steryl deacetylase activity,molecular_function
70950,GO:0034085,The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.,establishment of sister chromatid cohesion,biological_process
70951,GO:0034086,"The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.",maintenance of sister chromatid cohesion,biological_process
70952,GO:0034087,The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.,establishment of mitotic sister chromatid cohesion,biological_process
70953,GO:0034088,"The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.",maintenance of mitotic sister chromatid cohesion,biological_process
70954,GO:0034089,The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.,establishment of meiotic sister chromatid cohesion,biological_process
70955,GO:0034090,"The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.",maintenance of meiotic sister chromatid cohesion,biological_process
70956,GO:0034091,Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.,regulation of maintenance of sister chromatid cohesion,biological_process
70957,GO:0034092,Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.,negative regulation of maintenance of sister chromatid cohesion,biological_process
70958,GO:0034093,Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.,positive regulation of maintenance of sister chromatid cohesion,biological_process
70959,GO:0034094,Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.,regulation of maintenance of meiotic sister chromatid cohesion,biological_process
70960,GO:0034095,Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.,negative regulation of maintenance of meiotic sister chromatid cohesion,biological_process
70961,GO:0034096,Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.,positive regulation of maintenance of meiotic sister chromatid cohesion,biological_process
70962,GO:0034097,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.",response to cytokine,biological_process
70963,GO:0034098,"A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).",VCP-NPL4-UFD1 AAA ATPase complex,cellular_component
70964,GO:0034099,"A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.",luminal surveillance complex,cellular_component
70965,GO:0034101,Any process of regulating the production and elimination of erythrocytes within an organism.,erythrocyte homeostasis,biological_process
70966,GO:0034102,The selective elimination of erythrocytes from the body by autoregulatory mechanisms.,erythrocyte clearance,biological_process
70967,GO:0034103,"Any process that modulates the frequency, rate, or extent of tissue remodeling.",regulation of tissue remodeling,biological_process
70968,GO:0034104,"Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.",negative regulation of tissue remodeling,biological_process
70969,GO:0034105,"Any process that activates or increases the frequency, rate, or extent of tissue remodeling.",positive regulation of tissue remodeling,biological_process
70970,GO:0034106,"Any process that modulates the frequency, rate, or extent of erythrocyte clearance.",regulation of erythrocyte clearance,biological_process
70971,GO:0034107,"Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.",negative regulation of erythrocyte clearance,biological_process
70972,GO:0034108,"Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.",positive regulation of erythrocyte clearance,biological_process
70973,GO:0034109,The attachment of a cell to a second cell of the identical type via adhesion molecules.,homotypic cell-cell adhesion,biological_process
70974,GO:0034110,"Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.",regulation of homotypic cell-cell adhesion,biological_process
70975,GO:0034111,"Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.",negative regulation of homotypic cell-cell adhesion,biological_process
70976,GO:0034112,"Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.",positive regulation of homotypic cell-cell adhesion,biological_process
70977,GO:0034113,The attachment of a cell to a cell of a different type via adhesion molecules.,heterotypic cell-cell adhesion,biological_process
70978,GO:0034114,"Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.",regulation of heterotypic cell-cell adhesion,biological_process
70979,GO:0034115,"Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.",negative regulation of heterotypic cell-cell adhesion,biological_process
70980,GO:0034116,"Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.",positive regulation of heterotypic cell-cell adhesion,biological_process
70981,GO:0034117,The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.,erythrocyte aggregation,biological_process
70982,GO:0034118,"Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.",regulation of erythrocyte aggregation,biological_process
70983,GO:0034119,"Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.",negative regulation of erythrocyte aggregation,biological_process
70984,GO:0034120,"Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.",positive regulation of erythrocyte aggregation,biological_process
70985,GO:0034121,"Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.",regulation of toll-like receptor signaling pathway,biological_process
70986,GO:0034122,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.",negative regulation of toll-like receptor signaling pathway,biological_process
70987,GO:0034123,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.",positive regulation of toll-like receptor signaling pathway,biological_process
70988,GO:0034124,"Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.",regulation of MyD88-dependent toll-like receptor signaling pathway,biological_process
70989,GO:0034125,"Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.",negative regulation of MyD88-dependent toll-like receptor signaling pathway,biological_process
70990,GO:0034126,"Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.",positive regulation of MyD88-dependent toll-like receptor signaling pathway,biological_process
70991,GO:0034127,"Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.",regulation of MyD88-independent toll-like receptor signaling pathway,biological_process
70992,GO:0034128,"Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.",negative regulation of MyD88-independent toll-like receptor signaling pathway,biological_process
70993,GO:0034129,"Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.",positive regulation of MyD88-independent toll-like receptor signaling pathway,biological_process
70994,GO:0034130,The series of molecular signals initiated by a ligand binding to toll-like receptor 1.,toll-like receptor 1 signaling pathway,biological_process
70995,GO:0034131,"Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.",regulation of toll-like receptor 1 signaling pathway,biological_process
70996,GO:0034132,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.",negative regulation of toll-like receptor 1 signaling pathway,biological_process
70997,GO:0034133,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.",positive regulation of toll-like receptor 1 signaling pathway,biological_process
70998,GO:0034134,The series of molecular signals initiated by a ligand binding to toll-like receptor 2.,toll-like receptor 2 signaling pathway,biological_process
70999,GO:0034135,"Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.",regulation of toll-like receptor 2 signaling pathway,biological_process
71000,GO:0034136,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.",negative regulation of toll-like receptor 2 signaling pathway,biological_process
71001,GO:0034137,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.",positive regulation of toll-like receptor 2 signaling pathway,biological_process
71002,GO:0034138,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3.,toll-like receptor 3 signaling pathway,biological_process
71003,GO:0034139,"Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.",regulation of toll-like receptor 3 signaling pathway,biological_process
71004,GO:0034140,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.",negative regulation of toll-like receptor 3 signaling pathway,biological_process
71005,GO:0034141,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.",positive regulation of toll-like receptor 3 signaling pathway,biological_process
71006,GO:0034142,The series of molecular signals initiated by a ligand binding to toll-like receptor 4.,toll-like receptor 4 signaling pathway,biological_process
71007,GO:0034143,"Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.",regulation of toll-like receptor 4 signaling pathway,biological_process
71008,GO:0034144,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.",negative regulation of toll-like receptor 4 signaling pathway,biological_process
71009,GO:0034145,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.",positive regulation of toll-like receptor 4 signaling pathway,biological_process
71010,GO:0034146,The series of molecular signals initiated by a ligand binding to toll-like receptor 5.,toll-like receptor 5 signaling pathway,biological_process
71011,GO:0034147,"Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.",regulation of toll-like receptor 5 signaling pathway,biological_process
71012,GO:0034148,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.",negative regulation of toll-like receptor 5 signaling pathway,biological_process
71013,GO:0034149,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.",positive regulation of toll-like receptor 5 signaling pathway,biological_process
71014,GO:0034150,The series of molecular signals initiated by a ligand binding to toll-like receptor 6.,toll-like receptor 6 signaling pathway,biological_process
71015,GO:0034151,"Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.",regulation of toll-like receptor 6 signaling pathway,biological_process
71016,GO:0034152,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.",negative regulation of toll-like receptor 6 signaling pathway,biological_process
71017,GO:0034153,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.",positive regulation of toll-like receptor 6 signaling pathway,biological_process
71018,GO:0034154,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 7.,toll-like receptor 7 signaling pathway,biological_process
71019,GO:0034155,"Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.",regulation of toll-like receptor 7 signaling pathway,biological_process
71020,GO:0034156,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.",negative regulation of toll-like receptor 7 signaling pathway,biological_process
71021,GO:0034157,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.",positive regulation of toll-like receptor 7 signaling pathway,biological_process
71022,GO:0034158,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 8.,toll-like receptor 8 signaling pathway,biological_process
71023,GO:0034159,"Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.",regulation of toll-like receptor 8 signaling pathway,biological_process
71024,GO:0034160,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.",negative regulation of toll-like receptor 8 signaling pathway,biological_process
71025,GO:0034161,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.",positive regulation of toll-like receptor 8 signaling pathway,biological_process
71026,GO:0034162,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 9.,toll-like receptor 9 signaling pathway,biological_process
71027,GO:0034163,"Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.",regulation of toll-like receptor 9 signaling pathway,biological_process
71028,GO:0034164,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.",negative regulation of toll-like receptor 9 signaling pathway,biological_process
71029,GO:0034165,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.",positive regulation of toll-like receptor 9 signaling pathway,biological_process
71030,GO:0034166,The series of molecular signals initiated by a ligand binding to toll-like receptor 10.,toll-like receptor 10 signaling pathway,biological_process
71031,GO:0034167,"Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.",regulation of toll-like receptor 10 signaling pathway,biological_process
71032,GO:0034168,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.",negative regulation of toll-like receptor 10 signaling pathway,biological_process
71033,GO:0034169,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.",positive regulation of toll-like receptor 10 signaling pathway,biological_process
71034,GO:0034170,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 11.,toll-like receptor 11 signaling pathway,biological_process
71035,GO:0034171,"Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.",regulation of toll-like receptor 11 signaling pathway,biological_process
71036,GO:0034172,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.",negative regulation of toll-like receptor 11 signaling pathway,biological_process
71037,GO:0034173,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.",positive regulation of toll-like receptor 11 signaling pathway,biological_process
71038,GO:0034174,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 12.,toll-like receptor 12 signaling pathway,biological_process
71039,GO:0034175,"Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.",regulation of toll-like receptor 12 signaling pathway,biological_process
71040,GO:0034176,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.",negative regulation of toll-like receptor 12 signaling pathway,biological_process
71041,GO:0034177,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.",positive regulation of toll-like receptor 12 signaling pathway,biological_process
71042,GO:0034178,The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 13.,toll-like receptor 13 signaling pathway,biological_process
71043,GO:0034179,"Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.",regulation of toll-like receptor 13 signaling pathway,biological_process
71044,GO:0034180,"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.",negative regulation of toll-like receptor 13 signaling pathway,biological_process
71045,GO:0034181,"Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.",positive regulation of toll-like receptor 13 signaling pathway,biological_process
71046,GO:0034182,Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.,regulation of maintenance of mitotic sister chromatid cohesion,biological_process
71047,GO:0034183,Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.,negative regulation of maintenance of mitotic sister chromatid cohesion,biological_process
71048,GO:0034184,Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.,positive regulation of maintenance of mitotic sister chromatid cohesion,biological_process
71049,GO:0034185,"Binding to an apolipoprotein, the protein component of a lipoprotein complex.",apolipoprotein binding,molecular_function
71050,GO:0034186,Binding to apolipoprotein A-I.,apolipoprotein A-I binding,molecular_function
71051,GO:0034188,Combining with an apolipoprotein A-I receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,apolipoprotein A-I receptor activity,molecular_function
71052,GO:0034189,"Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.",very-low-density lipoprotein particle binding,molecular_function
71053,GO:0034190,Binding to an apolipoprotein receptor.,apolipoprotein receptor binding,molecular_function
71054,GO:0034191,Binding to an apolipoprotein A-I receptor.,apolipoprotein A-I receptor binding,molecular_function
71055,GO:0034194,"The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.",D-galactonate catabolic process,biological_process
71056,GO:0034195,"The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.",L-galactonate catabolic process,biological_process
71057,GO:0034196,"The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.",acylglycerol transport,biological_process
71058,GO:0034197,"The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.",triglyceride transport,biological_process
71059,GO:0034198,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.",cellular response to amino acid starvation,biological_process
71060,GO:0034199,Any process that initiates the activity of the inactive enzyme protein kinase A.,activation of protein kinase A activity,biological_process
71061,GO:0034200,"Catalysis of the reaction: D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-beta-D-manno-heptose 1-phosphate + phosphate.","D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity",molecular_function
71062,GO:0034201,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.",response to oleic acid,biological_process
71063,GO:0034202,"Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",glycolipid floppase activity,molecular_function
71064,GO:0034203,"The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.",glycolipid translocation,biological_process
71065,GO:0034204,"The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.",lipid translocation,biological_process
71066,GO:0034205,The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).,amyloid-beta formation,biological_process
71067,GO:0034206,A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.,enhanceosome,cellular_component
71068,GO:0034211,GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.,GTP-dependent protein kinase activity,molecular_function
71069,GO:0034212,"Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.",protein N-acetyltransferase activity,molecular_function
71070,GO:0034213,"The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.",quinolinate catabolic process,biological_process
71071,GO:0034214,"The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.",protein hexamerization,biological_process
71072,GO:0034215,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).,thiamine:proton symporter activity,molecular_function
71073,GO:0034216,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity thiamine:proton symporter activity,molecular_function
71074,GO:0034219,The process in which a carbohydrate is transported across a membrane.,carbohydrate transmembrane transport,biological_process
71075,GO:0034220,A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.,monoatomic ion transmembrane transport,biological_process
71076,GO:0034224,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.",cellular response to zinc ion starvation,biological_process
71077,GO:0034227,The addition a sulfur atom to a nucleotide in a tRNA molecule.,tRNA thio-modification,biological_process
71078,GO:0034228,"Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.",ethanolamine transmembrane transporter activity,molecular_function
71079,GO:0034229,"The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.",ethanolamine transport,biological_process
71080,GO:0034230,"The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.",enkephalin processing,biological_process
71081,GO:0034231,The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).,islet amyloid polypeptide processing,biological_process
71082,GO:0034235,Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.,GPI anchor binding,molecular_function
71083,GO:0034236,Binding to one or both of the catalytic subunits of protein kinase A.,protein kinase A catalytic subunit binding,molecular_function
71084,GO:0034237,Binding to one or both of the regulatory subunits of protein kinase A.,protein kinase A regulatory subunit binding,molecular_function
71085,GO:0034238,The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.,macrophage fusion,biological_process
71086,GO:0034239,"Any process that modulates the frequency, rate or extent of macrophage fusion.",regulation of macrophage fusion,biological_process
71087,GO:0034240,"Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.",negative regulation of macrophage fusion,biological_process
71088,GO:0034241,"Any process that activates or increases the frequency, rate or extent of macrophage fusion.",positive regulation of macrophage fusion,biological_process
71089,GO:0034242,"Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.",negative regulation of syncytium formation by plasma membrane fusion,biological_process
71090,GO:0034243,"Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.",regulation of transcription elongation by RNA polymerase II,biological_process
71091,GO:0034244,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.",negative regulation of transcription elongation by RNA polymerase II,biological_process
71092,GO:0034245,"A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in...",mitochondrial DNA-directed RNA polymerase complex,cellular_component
71093,GO:0034246,Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase.,mitochondrial transcription factor activity,molecular_function
71094,GO:0034247,The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.,snoRNA splicing,biological_process
71095,GO:0034254,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.",regulation of urea catabolic process,biological_process
71096,GO:0034256,Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.,chlorophyll(ide) b reductase activity,molecular_function
71097,GO:0034257,"Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.",nicotinamide riboside transmembrane transporter activity,molecular_function
71098,GO:0034258,"The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nicotinamide riboside transport,biological_process
71099,GO:0034260,Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.,negative regulation of GTPase activity,biological_process
71100,GO:0034263,The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.,positive regulation of autophagy in response to ER overload,biological_process
71101,GO:0034265,The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.,isopentenyl adenine biosynthetic process,biological_process
71102,GO:0034266,The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.,isopentenyl adenine catabolic process,biological_process
71103,GO:0034270,"A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p.",Cvt complex,cellular_component
71104,GO:0034271,"A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.","phosphatidylinositol 3-kinase complex, class III, type I",cellular_component
71105,GO:0034272,"A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.","phosphatidylinositol 3-kinase complex, class III, type II",cellular_component
71106,GO:0034274,"A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.",Atg12-Atg5-Atg16 complex,cellular_component
71107,GO:0034275,"The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.",kynurenic acid metabolic process,biological_process
71108,GO:0034276,"The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.",kynurenic acid biosynthetic process,biological_process
71109,GO:0034277,"Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.","ent-cassa-12,15-diene synthase activity",molecular_function
71110,GO:0034278,Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.,stemar-13-ene synthase activity,molecular_function
71111,GO:0034279,"Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.","syn-pimara-7,15-diene synthase activity",molecular_function
71112,GO:0034280,"Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.",ent-sandaracopimaradiene synthase activity,molecular_function
71113,GO:0034281,Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.,ent-isokaurene synthase activity,molecular_function
71114,GO:0034282,"Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.","ent-pimara-8(14),15-diene synthase activity",molecular_function
71115,GO:0034283,Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.,syn-stemod-13(17)-ene synthase activity,molecular_function
71116,GO:0034284,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.",response to monosaccharide,biological_process
71117,GO:0034285,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.",response to disaccharide,biological_process
71118,GO:0034286,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.",response to maltose,biological_process
71119,GO:0034287,The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.,detection of monosaccharide stimulus,biological_process
71120,GO:0034288,The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.,detection of disaccharide stimulus,biological_process
71121,GO:0034289,The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.,detection of maltose stimulus,biological_process
71122,GO:0034293,The formation of spores derived from the products of meiosis.,sexual sporulation,biological_process
71123,GO:0034294,"The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.",sexual spore wall assembly,biological_process
71124,GO:0034295,"The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.",basidiospore formation,biological_process
71125,GO:0034296,"The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.",zygospore formation,biological_process
71126,GO:0034297,"The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.",oidium formation,biological_process
71127,GO:0034298,The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.,arthrospore formation,biological_process
71128,GO:0034299,"The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.",reproductive blastospore formation,biological_process
71129,GO:0034300,"The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.",sporangiospore formation,biological_process
71130,GO:0034301,"The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.",endospore formation,biological_process
71131,GO:0034302,"The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.",akinete formation,biological_process
71132,GO:0034303,"The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, desiccation, and UV than vegetative myxobacteria.",myxospore formation,biological_process
71133,GO:0034304,"The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.",actinomycete-type spore formation,biological_process
71134,GO:0034305,"Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.",regulation of asexual sporulation,biological_process
71135,GO:0034306,"Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.",regulation of sexual sporulation,biological_process
71136,GO:0034307,"Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.",regulation of ascospore formation,biological_process
71137,GO:0034308,"The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.",primary alcohol metabolic process,biological_process
71138,GO:0034309,"The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.",primary alcohol biosynthetic process,biological_process
71139,GO:0034310,"The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.",primary alcohol catabolic process,biological_process
71140,GO:0034311,"The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.",diol metabolic process,biological_process
71141,GO:0034312,"The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.",diol biosynthetic process,biological_process
71142,GO:0034313,"The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.",diol catabolic process,biological_process
71143,GO:0034314,The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.,Arp2/3 complex-mediated actin nucleation,biological_process
71144,GO:0034315,"Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.",regulation of Arp2/3 complex-mediated actin nucleation,biological_process
71145,GO:0034316,"Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.",negative regulation of Arp2/3 complex-mediated actin nucleation,biological_process
71146,GO:0034318,Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.,alcohol O-acyltransferase activity,molecular_function
71147,GO:0034329,"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.",cell junction assembly,biological_process
71148,GO:0034330,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.",cell junction organization,biological_process
71149,GO:0034331,The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.,cell junction maintenance,biological_process
71150,GO:0034332,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.",adherens junction organization,biological_process
71151,GO:0034333,"The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.",adherens junction assembly,biological_process
71152,GO:0034334,The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.,adherens junction maintenance,biological_process
71153,GO:0034335,"Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not represe...",DNA negative supercoiling activity,molecular_function
71154,GO:0034336,Binding to an RNA molecule that has assumed an incorrect conformation.,misfolded RNA binding,molecular_function
71155,GO:0034337,The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.,RNA folding,biological_process
71156,GO:0034338,"Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.",short-chain carboxylesterase activity,molecular_function
71157,GO:0034340,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",response to type I interferon,biological_process
71158,GO:0034341,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.",response to type II interferon,biological_process
71159,GO:0034342,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.",response to type III interferon,biological_process
71160,GO:0034343,"The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.",type III interferon production,biological_process
71161,GO:0034344,"Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.",regulation of type III interferon production,biological_process
71162,GO:0034345,"Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.",negative regulation of type III interferon production,biological_process
71163,GO:0034346,"Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.",positive regulation of type III interferon production,biological_process
71164,GO:0034347,Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.,type III interferon binding,molecular_function
71165,GO:0034348,Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.,type III interferon receptor activity,molecular_function
71166,GO:0034349,"Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.",glial cell apoptotic process,biological_process
71167,GO:0034350,"Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.",regulation of glial cell apoptotic process,biological_process
71168,GO:0034351,"Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.",negative regulation of glial cell apoptotic process,biological_process
71169,GO:0034352,"Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.",positive regulation of glial cell apoptotic process,biological_process
71170,GO:0034353,"Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end.",mRNA 5'-diphosphatase activity,molecular_function
71171,GO:0034354,"The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), beginning with the catabolism of L-tryptophan into the precursor quinolinate. NAD+ is a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.",'de novo' NAD+ biosynthetic process from L-tryptophan,biological_process
71172,GO:0034355,"The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide (NAD+) from vitamin B3 derivatives (including nicotinic acid (NA) and nicotinamide (NAM)), beta-nicotinamide D-ribonucleotide (NMN), nicotinamide riboside (NR) or nicotinate riboside (NAR), without de novo synthesis.",NAD+ biosynthetic process via the salvage pathway,biological_process
71173,GO:0034357,"A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.",photosynthetic membrane,cellular_component
71174,GO:0034358,"A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.",plasma lipoprotein particle,cellular_component
71175,GO:0034359,"A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.",mature chylomicron,cellular_component
71176,GO:0034360,A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.,chylomicron remnant,cellular_component
71177,GO:0034361,"A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.",very-low-density lipoprotein particle,cellular_component
71178,GO:0034362,"A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.",low-density lipoprotein particle,cellular_component
71179,GO:0034363,"A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).",intermediate-density lipoprotein particle,cellular_component
71180,GO:0034364,A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.,high-density lipoprotein particle,cellular_component
71181,GO:0034365,A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).,discoidal high-density lipoprotein particle,cellular_component
71182,GO:0034366,"A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).",spherical high-density lipoprotein particle,cellular_component
71183,GO:0034367,"The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.",protein-containing complex remodeling,biological_process
71184,GO:0034368,"The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.",protein-lipid complex remodeling,biological_process
71185,GO:0034369,"The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).",plasma lipoprotein particle remodeling,biological_process
71186,GO:0034370,"The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.",triglyceride-rich lipoprotein particle remodeling,biological_process
71187,GO:0034371,"The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.",chylomicron remodeling,biological_process
71188,GO:0034372,"The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.",very-low-density lipoprotein particle remodeling,biological_process
71189,GO:0034373,"The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.",intermediate-density lipoprotein particle remodeling,biological_process
71190,GO:0034374,"The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.",low-density lipoprotein particle remodeling,biological_process
71191,GO:0034375,"The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.",high-density lipoprotein particle remodeling,biological_process
71192,GO:0034376,"The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.",conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle,biological_process
71193,GO:0034377,The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.,plasma lipoprotein particle assembly,biological_process
71194,GO:0034378,The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.,chylomicron assembly,biological_process
71195,GO:0034379,The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.,very-low-density lipoprotein particle assembly,biological_process
71196,GO:0034380,The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.,high-density lipoprotein particle assembly,biological_process
71197,GO:0034381,The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,plasma lipoprotein particle clearance,biological_process
71198,GO:0034382,The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.,chylomicron remnant clearance,biological_process
71199,GO:0034383,The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,low-density lipoprotein particle clearance,biological_process
71200,GO:0034384,The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,high-density lipoprotein particle clearance,biological_process
71201,GO:0034385,"A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.",triglyceride-rich plasma lipoprotein particle,cellular_component
71202,GO:0034386,Catalysis of the reaction: 2-oxoglutarate + 4-aminobutanoate = L-glutamate + succinate semialdehyde.,4-aminobutyrate:2-oxoglutarate transaminase activity,molecular_function
71203,GO:0034387,Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine. Also converts glyoxylate to glycine.,4-aminobutyrate:pyruvate transaminase activity,molecular_function
71204,GO:0034388,"A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.",Pwp2p-containing subcomplex of 90S preribosome,cellular_component
71205,GO:0034389,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.",lipid droplet organization,biological_process
71206,GO:0034390,"Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.",smooth muscle cell apoptotic process,biological_process
71207,GO:0034391,"Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.",regulation of smooth muscle cell apoptotic process,biological_process
71208,GO:0034392,"Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.",negative regulation of smooth muscle cell apoptotic process,biological_process
71209,GO:0034393,"Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.",positive regulation of smooth muscle cell apoptotic process,biological_process
71210,GO:0034394,"A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.",protein localization to cell surface,biological_process
71211,GO:0034397,"Any process in which a telomere is transported to, and/or maintained in, a specific location.",telomere localization,biological_process
71212,GO:0034398,The process in which a telomere is maintained in a specific location at the nuclear periphery.,telomere tethering at nuclear periphery,biological_process
71213,GO:0034399,The portion of the nuclear lumen proximal to the inner nuclear membrane.,nuclear periphery,cellular_component
71214,GO:0034400,"A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.",gerontoplast,cellular_component
71215,GO:0034403,Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.,alignment of 3' and 5' splice sites of mRNA,biological_process
71216,GO:0034404,"The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.",nucleobase-containing small molecule biosynthetic process,biological_process
71217,GO:0034405,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.",response to fluid shear stress,biological_process
71218,GO:0034406,"The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.",cell wall beta-glucan metabolic process,biological_process
71219,GO:0034407,"The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.",cell wall (1->3)-beta-D-glucan metabolic process,biological_process
71220,GO:0034408,"The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.",ascospore wall beta-glucan metabolic process,biological_process
71221,GO:0034409,"The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.",ascospore wall (1->3)-beta-D-glucan metabolic process,biological_process
71222,GO:0034410,"The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.",cell wall beta-glucan biosynthetic process,biological_process
71223,GO:0034411,"The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.",cell wall (1->3)-beta-D-glucan biosynthetic process,biological_process
71224,GO:0034412,"The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.",ascospore wall beta-glucan biosynthetic process,biological_process
71225,GO:0034413,"The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.",ascospore wall (1->3)-beta-D-glucan biosynthetic process,biological_process
71226,GO:0034417,"Catalysis of the reaction: (2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate.",bisphosphoglycerate 3-phosphatase activity,molecular_function
71227,GO:0034418,"The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.",urate biosynthetic process,biological_process
71228,GO:0034421,"The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.",post-translational protein acetylation,biological_process
71229,GO:0034422,The volume enclosed by the membrane of an aleurone grain.,aleurone grain lumen,cellular_component
71230,GO:0034423,The volume enclosed within the autophagosome double-membrane.,autophagosome lumen,cellular_component
71231,GO:0034424,"A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.",Vps55/Vps68 complex,cellular_component
71232,GO:0034425,The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.,etioplast envelope,cellular_component
71233,GO:0034426,Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.,etioplast membrane,cellular_component
71234,GO:0034429,"Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.",tectobulbar tract morphogenesis,biological_process
71235,GO:0034430,The single layer of phopholipids surrounding a lipid storage body.,monolayer-surrounded lipid storage body outer lipid monolayer,cellular_component
71236,GO:0034431,Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.,bis(5'-adenosyl)-hexaphosphatase activity,molecular_function
71237,GO:0034432,Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.,bis(5'-adenosyl)-pentaphosphatase activity,molecular_function
71238,GO:0034436,"The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycoprotein transport,biological_process
71239,GO:0034439,The modification of a lipoprotein by oxidation of the lipid group.,lipoprotein lipid oxidation,biological_process
71240,GO:0034440,"The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.",lipid oxidation,biological_process
71241,GO:0034441,The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids.,plasma lipoprotein particle oxidation,biological_process
71242,GO:0034442,"Any process that modulates the frequency, rate or extent of lipoprotein oxidation.",regulation of lipoprotein oxidation,biological_process
71243,GO:0034443,"Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.",negative regulation of lipoprotein oxidation,biological_process
71244,GO:0034444,"Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.",regulation of plasma lipoprotein oxidation,biological_process
71245,GO:0034445,"Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.",negative regulation of plasma lipoprotein oxidation,biological_process
71246,GO:0034446,The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.,substrate adhesion-dependent cell spreading,biological_process
71247,GO:0034447,The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,very-low-density lipoprotein particle clearance,biological_process
71248,GO:0034450,"Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.",ubiquitin-ubiquitin ligase activity,molecular_function
71249,GO:0034451,A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.,centriolar satellite,cellular_component
71250,GO:0034452,Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity.,dynactin binding,molecular_function
71251,GO:0034453,Any process in which a microtubule is maintained in a specific location in a cell.,microtubule anchoring,biological_process
71252,GO:0034454,Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.,microtubule anchoring at centrosome,biological_process
71253,GO:0034455,"A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.",t-UTP complex,cellular_component
71254,GO:0034456,"A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.",UTP-C complex,cellular_component
71255,GO:0034457,"A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.",Mpp10 complex,cellular_component
71256,GO:0034458,"Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.",3'-5' RNA helicase activity,molecular_function
71257,GO:0034460,The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.,uropod assembly,biological_process
71258,GO:0034461,The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.,uropod retraction,biological_process
71259,GO:0034462,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.",small-subunit processome assembly,biological_process
71260,GO:0034463,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.",90S preribosome assembly,biological_process
71261,GO:0034464,"A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.",BBSome,cellular_component
71262,GO:0034465,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.",response to carbon monoxide,biological_process
71263,GO:0034466,The volume enclosed by the membrane of a chromaffin granule.,chromaffin granule lumen,cellular_component
71264,GO:0034467,The volume enclosed by the membrane of an esterosome.,esterosome lumen,cellular_component
71265,GO:0034468,The volume enclosed by the membrane of a glycosome.,glycosome lumen,cellular_component
71266,GO:0034469,"The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.",Golgi stack lumen,cellular_component
71267,GO:0034472,Any process involved in forming the mature 3' end of an snRNA molecule.,snRNA 3'-end processing,biological_process
71268,GO:0034473,Any process involved in forming the mature 3' end of a U1 snRNA molecule.,U1 snRNA 3'-end processing,biological_process
71269,GO:0034474,Any process involved in forming the mature 3' end of a U2 snRNA molecule.,U2 snRNA 3'-end processing,biological_process
71270,GO:0034475,Any process involved in forming the mature 3' end of a U4 snRNA molecule.,U4 snRNA 3'-end processing,biological_process
71271,GO:0034476,Any process involved in forming the mature 3' end of a U5 snRNA molecule.,U5 snRNA 3'-end processing,biological_process
71272,GO:0034477,Any process involved in forming the mature 3' end of a U6 snRNA molecule.,U6 snRNA 3'-end processing,biological_process
71273,GO:0034478,"The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.",phosphatidylglycerol catabolic process,biological_process
71274,GO:0034479,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycerol 3-phosphate + a 1,2-diacyl-sn-glycerol + H+.",phosphatidylglycerol phospholipase C activity,molecular_function
71275,GO:0034480,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.",phosphatidylcholine phospholipase C activity,molecular_function
71276,GO:0034481,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.",chondroitin sulfotransferase activity,molecular_function
71277,GO:0034482,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.",chondroitin 2-sulfotransferase activity,molecular_function
71278,GO:0034483,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.",heparan sulfate sulfotransferase activity,molecular_function
71279,GO:0034484,"The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.",raffinose catabolic process,biological_process
71280,GO:0034485,"1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.","phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity",molecular_function
71281,GO:0034486,The process in which a solute is transported from one side of the vacuolar membrane to the other.,vacuolar transmembrane transport,biological_process
71282,GO:0034487,The process in which an amino acid is transported from one side of the vacuolar membrane to the other.,vacuolar amino acid transmembrane transport,biological_process
71283,GO:0034488,"The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.",basic amino acid transmembrane export from vacuole,biological_process
71284,GO:0034489,"The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.",neutral amino acid transmembrane export from vacuole,biological_process
71285,GO:0034490,The directed movement of basic amino acids into the vacuole across the vacuolar membrane.,basic amino acid transmembrane import into vacuole,biological_process
71286,GO:0034491,The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.,neutral amino acid transmembrane import into vacuole,biological_process
71287,GO:0034492,The volume enclosed by the hydrogenosome membrane.,hydrogenosome lumen,cellular_component
71288,GO:0034493,The volume enclosed by the melanosome membrane.,melanosome lumen,cellular_component
71289,GO:0034494,The volume enclosed by the microneme membrane.,microneme lumen,cellular_component
71290,GO:0034495,The volume enclosed by the protein storage vacuole membrane.,protein storage vacuole lumen,cellular_component
71291,GO:0034496,The controlled breakdown of the membranes of multivesicular bodies.,multivesicular body membrane disassembly,biological_process
71292,GO:0034497,"Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).",protein localization to phagophore assembly site,biological_process
71293,GO:0034498,The directed movement of substances from early endosomes to the Golgi.,early endosome to Golgi transport,biological_process
71294,GO:0034499,The directed movement of substances from late endosomes to the Golgi.,late endosome to Golgi transport,biological_process
71295,GO:0034501,"Any process in which a protein is transported to, or maintained at, the kinetochore.",protein localization to kinetochore,biological_process
71296,GO:0034502,"Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.",protein localization to chromosome,biological_process
71297,GO:0034503,"Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.",protein localization to nucleolar rDNA repeats,biological_process
71298,GO:0034504,A process in which a protein transports or maintains the localization of another protein to the nucleus.,protein localization to nucleus,biological_process
71299,GO:0034505,"The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.",tooth mineralization,biological_process
71300,GO:0034506,"The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.","chromosome, centromeric core domain",cellular_component
71301,GO:0034510,The cell cycle process in which centromeres are physically detached from each other during chromosome separation.,centromere separation,biological_process
71302,GO:0034511,Binding to a U3 small nucleolar RNA.,U3 snoRNA binding,molecular_function
71303,GO:0034512,Binding to a box C/D small nucleolar RNA.,box C/D sno(s)RNA binding,molecular_function
71304,GO:0034513,Binding to a box H/ACA small nucleolar RNA.,box H/ACA snoRNA binding,molecular_function
71305,GO:0034514,The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.,mitochondrial unfolded protein response,biological_process
71306,GO:0034515,An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.,proteasome storage granule,cellular_component
71307,GO:0034516,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.",response to vitamin B6,biological_process
71308,GO:0034517,The selective degradation of mature ribosomes by macroautophagy.,ribophagy,biological_process
71309,GO:0034518,A protein complex that binds to an RNA cap structure to mediate RNA processing and/or translation initiation.,RNA cap binding complex,cellular_component
71310,GO:0034545,Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.,fumarylpyruvate hydrolase activity,molecular_function
71311,GO:0034551,"The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.",mitochondrial respiratory chain complex III assembly,biological_process
71312,GO:0034552,"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.",respiratory chain complex II assembly,biological_process
71313,GO:0034553,"The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.",mitochondrial respiratory chain complex II assembly,biological_process
71314,GO:0034583,"Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.",21U-RNA binding,molecular_function
71315,GO:0034584,"Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.",piRNA binding,molecular_function
71316,GO:0034585,"The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.",21U-RNA metabolic process,biological_process
71317,GO:0034586,"The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.",21U-RNA catabolic process,biological_process
71318,GO:0034587,A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.,piRNA processing,biological_process
71319,GO:0034589,"The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hydroxyproline transport,biological_process
71320,GO:0034590,Enables the transfer of L-hydroxyproline from one side of a membrane to the other.,L-hydroxyproline transmembrane transporter activity,molecular_function
71321,GO:0034591,The volume enclosed by the rhoptry membrane.,rhoptry lumen,cellular_component
71322,GO:0034592,The volume enclosed by the synaptic vesicle membrane.,synaptic vesicle lumen,cellular_component
71323,GO:0034593,Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.,phosphatidylinositol bisphosphate phosphatase activity,molecular_function
71324,GO:0034594,Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.,phosphatidylinositol trisphosphate phosphatase activity,molecular_function
71325,GO:0034595,Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.,phosphatidylinositol phosphate 5-phosphatase activity,molecular_function
71326,GO:0034596,Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.,phosphatidylinositol phosphate 4-phosphatase activity,molecular_function
71327,GO:0034597,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.","phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity",molecular_function
71328,GO:0034598,"Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.",phosphothreonine lyase activity,molecular_function
71329,GO:0034599,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.",cellular response to oxidative stress,biological_process
71330,GO:0034605,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.",cellular response to heat,biological_process
71331,GO:0034606,"The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.",response to hermaphrodite contact,biological_process
71332,GO:0034607,"The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.",turning behavior involved in mating,biological_process
71333,GO:0034608,"Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.",vulval location,biological_process
71334,GO:0034609,"Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.",spicule insertion,biological_process
71335,GO:0034612,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.",response to tumor necrosis factor,biological_process
71336,GO:0034614,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.",cellular response to reactive oxygen species,biological_process
71337,GO:0034615,"A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.",GCH1 complex,cellular_component
71338,GO:0034616,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.",response to laminar fluid shear stress,biological_process
71339,GO:0034617,"Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.",tetrahydrobiopterin binding,molecular_function
71340,GO:0034618,Binding to 2-amino-5-(carbamimidamido)pentanoic acid.,arginine binding,molecular_function
71341,GO:0034620,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.",cellular response to unfolded protein,biological_process
71342,GO:0034625,Elongation of a fatty acid chain into which one C-C double bond has been introduced.,"fatty acid elongation, monounsaturated fatty acid",biological_process
71343,GO:0034626,Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced.,"fatty acid elongation, polyunsaturated fatty acid",biological_process
71344,GO:0034628,"The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), beginning with the catabolism of L-aspartate into the precursor quinolinate. NAD+ is a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.",'de novo' NAD+ biosynthetic process from L-aspartate,biological_process
71345,GO:0034630,"Any process in which a RITS complex is transported to, or maintained in, a specific location.",RITS complex localization,biological_process
71346,GO:0034631,Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.,microtubule anchoring at spindle pole body,biological_process
71347,GO:0034632,"Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.",retinol transmembrane transporter activity,molecular_function
71348,GO:0034633,"The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.",retinol transport,biological_process
71349,GO:0034634,"Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.",glutathione transmembrane transporter activity,molecular_function
71350,GO:0034635,"The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glutathione transport,biological_process
71351,GO:0034638,"The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.",phosphatidylcholine catabolic process,biological_process
71352,GO:0034639,Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.,L-amino acid efflux transmembrane transporter activity,molecular_function
71353,GO:0034640,"The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.",establishment of mitochondrion localization by microtubule attachment,biological_process
71354,GO:0034642,"The directed movement of a mitochondrion along a microfilament, mediated by motor proteins.",mitochondrion migration along actin filament,biological_process
71355,GO:0034643,"The directed movement of the mitochondrion to a specific location, by a process involving microtubules.","establishment of mitochondrion localization, microtubule-mediated",biological_process
71356,GO:0034644,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.",cellular response to UV,biological_process
71357,GO:0034646,A lipid monolayer that surrounds and encloses an organelle.,organelle-enclosing lipid monolayer,cellular_component
71358,GO:0034647,"Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.",histone H3K4me/H3K4me2/H3K4me3 demethylase activity,molecular_function
71359,GO:0034650,"The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.",cortisol metabolic process,biological_process
71360,GO:0034651,"The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.",cortisol biosynthetic process,biological_process
71361,GO:0034653,"The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.",retinoic acid catabolic process,biological_process
71362,GO:0034654,"The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.",nucleobase-containing compound biosynthetic process,biological_process
71363,GO:0034655,"The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.",nucleobase-containing compound catabolic process,biological_process
71364,GO:0034656,"The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.",nucleobase-containing small molecule catabolic process,biological_process
71365,GO:0034657,"A protein complex with ubiquitin ligase activity that, in Saccharomyces cerevisiae, is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. It appears to play a broader role in cellular homeostasis and development in other species.",GID complex,cellular_component
71366,GO:0034658,Enables the transfer of isopropylmalate from one side of a membrane to the other.,isopropylmalate transmembrane transporter activity,molecular_function
71367,GO:0034659,"The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",isopropylmalate transport,biological_process
71368,GO:0034662,"A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.",CFTR-NHERF-ezrin complex,cellular_component
71369,GO:0034663,"A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.",endoplasmic reticulum chaperone complex,cellular_component
71370,GO:0034664,"A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.",Ig heavy chain-bound endoplasmic reticulum chaperone complex,cellular_component
71371,GO:0034665,An integrin complex that comprises one alpha1 subunit and one beta1 subunit.,integrin alpha1-beta1 complex,cellular_component
71372,GO:0034666,An integrin complex that comprises one alpha2 subunit and one beta1 subunit.,integrin alpha2-beta1 complex,cellular_component
71373,GO:0034667,An integrin complex that comprises one alpha3 subunit and one beta1 subunit.,integrin alpha3-beta1 complex,cellular_component
71374,GO:0034668,An integrin complex that comprises one alpha4 subunit and one beta1 subunit.,integrin alpha4-beta1 complex,cellular_component
71375,GO:0034669,An integrin complex that comprises one alpha4 subunit and one beta7 subunit.,integrin alpha4-beta7 complex,cellular_component
71376,GO:0034670,The directed movement of a motile cell or organism in response to the presence of arachidonic acid.,chemotaxis to arachidonate,biological_process
71377,GO:0034672,The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.,anterior/posterior pattern specification involved in pronephros development,biological_process
71378,GO:0034673,"A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.",inhibin-betaglycan-ActRII complex,cellular_component
71379,GO:0034674,An integrin complex that comprises one alpha5 subunit and one beta1 subunit.,integrin alpha5-beta1 complex,cellular_component
71380,GO:0034675,An integrin complex that comprises one alpha6 subunit and one beta1 subunit.,integrin alpha6-beta1 complex,cellular_component
71381,GO:0034676,An integrin complex that comprises one alpha6 subunit and one beta4 subunit.,integrin alpha6-beta4 complex,cellular_component
71382,GO:0034677,An integrin complex that comprises one alpha7 subunit and one beta1 subunit.,integrin alpha7-beta1 complex,cellular_component
71383,GO:0034678,An integrin complex that comprises one alpha8 subunit and one beta1 subunit.,integrin alpha8-beta1 complex,cellular_component
71384,GO:0034679,An integrin complex that comprises one alpha9 subunit and one beta1 subunit.,integrin alpha9-beta1 complex,cellular_component
71385,GO:0034680,An integrin complex that comprises one alpha10 subunit and one beta1 subunit.,integrin alpha10-beta1 complex,cellular_component
71386,GO:0034681,An integrin complex that comprises one alpha11 subunit and one beta1 subunit.,integrin alpha11-beta1 complex,cellular_component
71387,GO:0034682,An integrin complex that comprises one alphav subunit and one beta1 subunit.,integrin alphav-beta1 complex,cellular_component
71388,GO:0034683,An integrin complex that comprises one alphav subunit and one beta3 subunit.,integrin alphav-beta3 complex,cellular_component
71389,GO:0034684,An integrin complex that comprises one alphav subunit and one beta5 subunit.,integrin alphav-beta5 complex,cellular_component
71390,GO:0034685,An integrin complex that comprises one alphav subunit and one beta6 subunit.,integrin alphav-beta6 complex,cellular_component
71391,GO:0034686,An integrin complex that comprises one alphav subunit and one beta8 subunit.,integrin alphav-beta8 complex,cellular_component
71392,GO:0034687,An integrin complex that comprises one alphaL subunit and one beta2 subunit.,integrin alphaL-beta2 complex,cellular_component
71393,GO:0034688,An integrin complex that comprises one alphaM subunit and one beta2 subunit.,integrin alphaM-beta2 complex,cellular_component
71394,GO:0034689,An integrin complex that comprises one alphaX subunit and one beta2 subunit.,integrin alphaX-beta2 complex,cellular_component
71395,GO:0034690,An integrin complex that comprises one alphaD subunit and one beta2 subunit.,integrin alphaD-beta2 complex,cellular_component
71396,GO:0034691,An integrin complex that comprises one alphaE subunit and one beta7 subunit.,integrin alphaE-beta7 complex,cellular_component
71397,GO:0034692,"A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.",E.F.G complex,cellular_component
71398,GO:0034693,A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.,U11/U12 snRNP,cellular_component
71399,GO:0034694,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.",response to prostaglandin,biological_process
71400,GO:0034695,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.",response to prostaglandin E,biological_process
71401,GO:0034696,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.",response to prostaglandin F,biological_process
71402,GO:0034697,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.",response to prostaglandin I,biological_process
71403,GO:0034698,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.",response to gonadotropin,biological_process
71404,GO:0034699,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.",response to luteinizing hormone,biological_process
71405,GO:0034700,Catalysis of the reaction: D-allulose 6-phosphate = keto-D-fructose 6-phosphate.,allulose 6-phosphate 3-epimerase activity,molecular_function
71406,GO:0034701,Catalysis of the hydrolysis of a tripeptide.,tripeptidase activity,molecular_function
71407,GO:0034702,A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient.,monoatomic ion channel complex,cellular_component
71408,GO:0034703,An ion channel complex through which cations pass.,cation channel complex,cellular_component
71409,GO:0034704,An ion channel complex through which calcium ions pass.,calcium channel complex,cellular_component
71410,GO:0034705,An ion channel complex through which potassium ions pass.,potassium channel complex,cellular_component
71411,GO:0034706,An ion channel complex through which sodium ions pass.,sodium channel complex,cellular_component
71412,GO:0034707,An ion channel complex through which chloride ions pass.,chloride channel complex,cellular_component
71413,GO:0034708,A protein complex that possesses methyltransferase activity.,methyltransferase complex,cellular_component
71414,GO:0034709,"A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethyl...",methylosome,cellular_component
71415,GO:0034710,"Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.",inhibin complex binding,molecular_function
71416,GO:0034711,"Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.",inhibin binding,molecular_function
71417,GO:0034713,Binding to a type I transforming growth factor beta receptor.,type I transforming growth factor beta receptor binding,molecular_function
71418,GO:0034714,Binding to a type III transforming growth factor beta receptor.,type III transforming growth factor beta receptor binding,molecular_function
71419,GO:0034715,"A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.",pICln-Sm protein complex,cellular_component
71420,GO:0034716,"A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.",Gemin3-Gemin4-Gemin5 complex,cellular_component
71421,GO:0034717,"A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.",Gemin6-Gemin7-unrip complex,cellular_component
71422,GO:0034718,A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.,SMN-Gemin2 complex,cellular_component
71423,GO:0034719,"A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.",SMN-Sm protein complex,cellular_component
71424,GO:0034722,Catalysis of the cleavage of a gamma-linked glutamate bond.,gamma-glutamyl-peptidase activity,molecular_function
71425,GO:0034727,Degradation of a cell nucleus by microautophagy.,piecemeal microautophagy of the nucleus,biological_process
71426,GO:0034728,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.",nucleosome organization,biological_process
71427,GO:0034730,"An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.",SmD-containing SMN-Sm protein complex,cellular_component
71428,GO:0034731,"An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.",Lsm-containing SMN-Sm protein complex,cellular_component
71429,GO:0034732,"A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.",transcription factor TFIIIB-alpha complex,cellular_component
71430,GO:0034733,"A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.",transcription factor TFIIIB-beta complex,cellular_component
71431,GO:0034734,"A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.",transcription factor TFIIIC1 complex,cellular_component
71432,GO:0034735,"A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.",transcription factor TFIIIC2 complex,cellular_component
71433,GO:0034736,Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.,cholesterol O-acyltransferase activity,molecular_function
71434,GO:0034737,Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester.,ergosterol O-acyltransferase activity,molecular_function
71435,GO:0034738,Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.,lanosterol O-acyltransferase activity,molecular_function
71436,GO:0034739,Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.,"histone H4K16 deacetylase activity, hydrolytic mechanism",molecular_function
71437,GO:0034740,"A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.",TFIIIC-TOP1-SUB1 complex,cellular_component
71438,GO:0034741,"A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.",APC-tubulin-IQGAP1 complex,cellular_component
71439,GO:0034743,A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.,APC-IQGAP complex,cellular_component
71440,GO:0034744,"A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.",APC-IQGAP1-Cdc42 complex,cellular_component
71441,GO:0034745,"A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.",APC-IQGAP1-Rac1 complex,cellular_component
71442,GO:0034746,"A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.",APC-IQGAP1-CLIP-170 complex,cellular_component
71443,GO:0034748,"A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.",Par3-APC-KIF3A complex,cellular_component
71444,GO:0034749,A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.,Scrib-APC complex,cellular_component
71445,GO:0034750,"A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.",Scrib-APC-beta-catenin complex,cellular_component
71446,GO:0034751,"A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.",aryl hydrocarbon receptor complex,cellular_component
71447,GO:0034752,"An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.",cytosolic aryl hydrocarbon receptor complex,cellular_component
71448,GO:0034753,An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).,nuclear aryl hydrocarbon receptor complex,cellular_component
71449,GO:0034755,A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,iron ion transmembrane transport,biological_process
71450,GO:0034756,"Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of iron ion transport,biological_process
71451,GO:0034757,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of iron ion transport,biological_process
71452,GO:0034758,"Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of iron ion transport,biological_process
71453,GO:0034759,"Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.",regulation of iron ion transmembrane transport,biological_process
71454,GO:0034760,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.",negative regulation of iron ion transmembrane transport,biological_process
71455,GO:0034761,"Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.",positive regulation of iron ion transmembrane transport,biological_process
71456,GO:0034762,"Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.",regulation of transmembrane transport,biological_process
71457,GO:0034763,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.",negative regulation of transmembrane transport,biological_process
71458,GO:0034764,"Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.",positive regulation of transmembrane transport,biological_process
71459,GO:0034765,"Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.",regulation of monoatomic ion transmembrane transport,biological_process
71460,GO:0034766,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.",negative regulation of monoatomic ion transmembrane transport,biological_process
71461,GO:0034767,"Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.",positive regulation of monoatomic ion transmembrane transport,biological_process
71462,GO:0034768,Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.,(E)-beta-ocimene synthase activity,molecular_function
71463,GO:0034769,The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.,basement membrane disassembly,biological_process
71464,GO:0034774,The volume enclosed by the membrane of a secretory granule.,secretory granule lumen,cellular_component
71465,GO:0034775,A process in which glutathione is transported across a membrane.,glutathione transmembrane transport,biological_process
71466,GO:0034776,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.",response to histamine,biological_process
71467,GO:0034777,The volume enclosed by the membranes of a recycling endosome.,recycling endosome lumen,cellular_component
71468,GO:0034784,"Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.",pivalyl-CoA mutase activity,molecular_function
71469,GO:0034785,"Catalysis of the reaction: salicylate + NADH + O2 + H+ = 2,5-dihydroxybenzoate + NAD+ + H2O.",salicylate 5-hydroxylase (NADH) activity,molecular_function
71470,GO:0034824,Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.,citronellyl-CoA dehydrogenase activity,molecular_function
71471,GO:0034832,Catalysis of the reaction: (2E)-geranial + H2O + NAD+ = geranate + 2 H+ + NADH.,geranial dehydrogenase (NAD+) activity,molecular_function
71472,GO:0034856,"Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.","2-hydroxyhexa-2,4-dienoate hydratase activity",molecular_function
71473,GO:0034875,"Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.",caffeine oxidase activity,molecular_function
71474,GO:0034899,"Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.",trimethylamine monooxygenase activity,molecular_function
71475,GO:0034909,Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.,6-hydroxypseudooxynicotine dehydrogenase activity,molecular_function
71476,GO:0034938,Catalysis of the reaction: H+ + NADH + O2 + pyrrole-2-carboxylate = 5-hydroxypyrrole-2-carboxylate + H2O + NAD+.,pyrrole-2-carboxylate monooxygenase (NADH) activity,molecular_function
71477,GO:0034941,Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2.,pyrrole-2-carboxylate decarboxylase activity,molecular_function
71478,GO:0034959,The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.,endothelin maturation,biological_process
71479,GO:0034963,Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.,box C/D sno(s)RNA processing,biological_process
71480,GO:0034964,Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.,box H/ACA sno(s)RNA processing,biological_process
71481,GO:0034965,"Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.",intronic box C/D snoRNA processing,biological_process
71482,GO:0034966,"Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.",intronic box H/ACA snoRNA processing,biological_process
71483,GO:0034967,"A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.",Set3 complex,cellular_component
71484,GO:0034973,A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.,Sid2-Mob1 complex,cellular_component
71485,GO:0034974,"A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.",Swi5-Swi2 complex,cellular_component
71486,GO:0034975,"A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).",protein folding in endoplasmic reticulum,biological_process
71487,GO:0034976,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.",response to endoplasmic reticulum stress,biological_process
71488,GO:0034977,"A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.",ABIN2-NFKB1-MAP3K8 complex,cellular_component
71489,GO:0034978,"A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.",PDX1-PBX1b-MRG1 complex,cellular_component
71490,GO:0034979,"Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide.",NAD-dependent protein lysine deacetylase activity,molecular_function
71491,GO:0034980,"A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation.",FHL2-CREB complex,cellular_component
71492,GO:0034981,"A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation.",FHL3-CREB complex,cellular_component
71493,GO:0034982,"The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.",mitochondrial protein processing,biological_process
71494,GO:0034983,The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.,peptidyl-lysine deacetylation,biological_process
71495,GO:0034985,"Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.",Ecsit-NDUFAF1 complex,cellular_component
71496,GO:0034986,Directly binding to and delivering iron ions to a target protein.,iron chaperone activity,molecular_function
71497,GO:0034987,Binding to one or more specific sites on an immunoglobulin receptor molecule.,immunoglobulin receptor binding,molecular_function
71498,GO:0034988,Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.,Fc-gamma receptor I complex binding,molecular_function
71499,GO:0034992,A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.,microtubule organizing center attachment site,cellular_component
71500,GO:0034993,"A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.",meiotic nuclear membrane microtubule tethering complex,cellular_component
71501,GO:0034994,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.",microtubule organizing center attachment site organization,biological_process
71502,GO:0034995,A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.,SC5b-7 complex,cellular_component
71503,GO:0034996,"A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.",RasGAP-Fyn-Lyn-Yes complex,cellular_component
71504,GO:0034997,"A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.",alphav-beta5 integrin-vitronectin complex,cellular_component
71505,GO:0035001,Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.,"dorsal trunk growth, open tracheal system",biological_process
71506,GO:0035002,"The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.","liquid clearance, open tracheal system",biological_process
71507,GO:0035003,"The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.",subapical complex,cellular_component
71508,GO:0035005,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+.",1-phosphatidylinositol-4-phosphate 3-kinase activity,molecular_function
71509,GO:0035006,"The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.",melanization defense response,biological_process
71510,GO:0035007,"Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.",regulation of melanization defense response,biological_process
71511,GO:0035008,Any process that increases the rate or extent of the melanization defense response during injury or invasion.,positive regulation of melanization defense response,biological_process
71512,GO:0035009,Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.,negative regulation of melanization defense response,biological_process
71513,GO:0035010,"Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.",encapsulation of foreign target,biological_process
71514,GO:0035011,"Formation of a multilayered, melanized sheath of cells around a foreign invader.",melanotic encapsulation of foreign target,biological_process
71515,GO:0035013,Combining with the peptide myosuppressin to initiate a change in cell activity.,myosuppressin receptor activity,molecular_function
71516,GO:0035014,Modulates the activity of a phosphatidylinositol 3-kinase (PI3K). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.,phosphatidylinositol 3-kinase regulator activity,molecular_function
71517,GO:0035015,The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.,elongation of arista core,biological_process
71518,GO:0035016,The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.,elongation of arista lateral,biological_process
71519,GO:0035017,The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.,cuticle pattern formation,biological_process
71520,GO:0035018,The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.,adult chitin-based cuticle pattern formation,biological_process
71521,GO:0035019,"Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.",somatic stem cell population maintenance,biological_process
71522,GO:0035020,"Any process that modulates the frequency, rate or extent of Rac protein signal transduction.",regulation of Rac protein signal transduction,biological_process
71523,GO:0035021,"Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.",negative regulation of Rac protein signal transduction,biological_process
71524,GO:0035022,"Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.",positive regulation of Rac protein signal transduction,biological_process
71525,GO:0035023,"Any process that modulates the frequency, rate or extent of Rho protein signal transduction.",regulation of Rho protein signal transduction,biological_process
71526,GO:0035024,"Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.",negative regulation of Rho protein signal transduction,biological_process
71527,GO:0035025,"Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.",positive regulation of Rho protein signal transduction,biological_process
71528,GO:0035026,"The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.",leading edge cell differentiation,biological_process
71529,GO:0035027,The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.,leading edge cell fate commitment,biological_process
71530,GO:0035028,"The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.",leading edge cell fate determination,biological_process
71531,GO:0035029,The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.,"dorsal closure, leading edge cell fate commitment",biological_process
71532,GO:0035032,A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).,"phosphatidylinositol 3-kinase complex, class III",cellular_component
71533,GO:0035033,Binds to and modulates the activity of histone deacetylase.,histone deacetylase regulator activity,molecular_function
71534,GO:0035034,Binds to and modulates the activity of histone acetyltransferase.,histone acetyltransferase regulator activity,molecular_function
71535,GO:0035035,Binding to an histone acetyltransferase.,histone acetyltransferase binding,molecular_function
71536,GO:0035036,The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.,sperm-egg recognition,biological_process
71537,GO:0035037,"An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.",sperm entry,biological_process
71538,GO:0035038,Assembly of the haploid nucleus of the unfertilized egg.,female pronucleus assembly,biological_process
71539,GO:0035039,The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.,male pronucleus assembly,biological_process
71540,GO:0035040,"Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.",sperm nuclear envelope removal,biological_process
71541,GO:0035041,Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization.,sperm DNA decondensation,biological_process
71542,GO:0035043,"Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.",male pronuclear envelope synthesis,biological_process
71543,GO:0035044,Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.,sperm aster formation,biological_process
71544,GO:0035045,"The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.",sperm plasma membrane disassembly,biological_process
71545,GO:0035046,The directed movement of the male and female pronuclei towards each other prior to their fusion.,pronuclear migration,biological_process
71546,GO:0035047,"The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.",centrosomal and pronuclear rotation,biological_process
71547,GO:0035050,"The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.",embryonic heart tube development,biological_process
71548,GO:0035051,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.,cardiocyte differentiation,biological_process
71549,GO:0035052,The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.,dorsal vessel aortic cell fate commitment,biological_process
71550,GO:0035053,The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.,dorsal vessel heart proper cell fate commitment,biological_process
71551,GO:0035054,"The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.",embryonic heart tube anterior/posterior pattern specification,biological_process
71552,GO:0035059,"A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.",RCAF complex,cellular_component
71553,GO:0035060,"A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.",brahma complex,cellular_component
71554,GO:0035061,"A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).",interchromatin granule,cellular_component
71555,GO:0035062,A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).,omega speckle,cellular_component
71556,GO:0035063,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.",nuclear speck organization,biological_process
71557,GO:0035069,"The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.",larval midgut histolysis,biological_process
71558,GO:0035070,"The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.",salivary gland histolysis,biological_process
71559,GO:0035073,"The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.",pupariation,biological_process
71560,GO:0035074,"The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.",pupation,biological_process
71561,GO:0035075,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.",response to ecdysone,biological_process
71562,GO:0035076,"A nuclear receptor-mediated signaling pathway initiated by an ecdysone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",ecdysone receptor signaling pathway,biological_process
71563,GO:0035077,The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.,ecdysone-mediated polytene chromosome puffing,biological_process
71564,GO:0035078,Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.,induction of programmed cell death by ecdysone,biological_process
71565,GO:0035079,"The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.",polytene chromosome puffing,biological_process
71566,GO:0035080,The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.,heat shock-mediated polytene chromosome puffing,biological_process
71567,GO:0035081,Any process induced by hormones that directly activates any of the steps required for programmed cell death.,induction of programmed cell death by hormones,biological_process
71568,GO:0035082,"The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.",axoneme assembly,biological_process
71569,GO:0035088,"Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.",establishment or maintenance of apical/basal cell polarity,biological_process
71570,GO:0035089,The specification and formation of the polarity of a cell along its apical/basal axis.,establishment of apical/basal cell polarity,biological_process
71571,GO:0035090,Retaining the established polarization of a cell along its apical/basal axis.,maintenance of apical/basal cell polarity,biological_process
71572,GO:0035091,"Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.",phosphatidylinositol binding,molecular_function
71573,GO:0035092,The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.,sperm DNA condensation,biological_process
71574,GO:0035094,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.",response to nicotine,biological_process
71575,GO:0035095,Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.,behavioral response to nicotine,biological_process
71576,GO:0035096,"The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.",larval midgut cell programmed cell death,biological_process
71577,GO:0035097,A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.,histone methyltransferase complex,cellular_component
71578,GO:0035098,"A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.",ESC/E(Z) complex,cellular_component
71579,GO:0035099,"The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the...",hemocyte migration,biological_process
71580,GO:0035100,"Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.",ecdysone binding,molecular_function
71581,GO:0035101,A histone chaperone complex that facilitates nucleosome disassembly and reassembly upon DNA or RNA polymerase passage.,FACT complex,cellular_component
71582,GO:0035102,A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.,PRC1 complex,cellular_component
71583,GO:0035106,Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.,operant conditioning,biological_process
71584,GO:0035107,"The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.",appendage morphogenesis,biological_process
71585,GO:0035108,The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.,limb morphogenesis,biological_process
71586,GO:0035112,"The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.",genitalia morphogenesis,biological_process
71587,GO:0035113,"The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.",embryonic appendage morphogenesis,biological_process
71588,GO:0035114,The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.,imaginal disc-derived appendage morphogenesis,biological_process
71589,GO:0035115,"The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.",embryonic forelimb morphogenesis,biological_process
71590,GO:0035116,"The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.",embryonic hindlimb morphogenesis,biological_process
71591,GO:0035118,"The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.",embryonic pectoral fin morphogenesis,biological_process
71592,GO:0035119,"The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.",embryonic pelvic fin morphogenesis,biological_process
71593,GO:0035120,"The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.",post-embryonic appendage morphogenesis,biological_process
71594,GO:0035122,"The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.",embryonic medial fin morphogenesis,biological_process
71595,GO:0035123,"The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.",embryonic dorsal fin morphogenesis,biological_process
71596,GO:0035124,"The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.",embryonic caudal fin morphogenesis,biological_process
71597,GO:0035125,"The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.",embryonic anal fin morphogenesis,biological_process
71598,GO:0035126,"The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.",post-embryonic genitalia morphogenesis,biological_process
71599,GO:0035127,"The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.",post-embryonic limb morphogenesis,biological_process
71600,GO:0035128,"The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.",post-embryonic forelimb morphogenesis,biological_process
71601,GO:0035129,"The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.",post-embryonic hindlimb morphogenesis,biological_process
71602,GO:0035130,"The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.",post-embryonic pectoral fin morphogenesis,biological_process
71603,GO:0035131,"The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.",post-embryonic pelvic fin morphogenesis,biological_process
71604,GO:0035132,"The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.",post-embryonic medial fin morphogenesis,biological_process
71605,GO:0035133,"The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.",post-embryonic caudal fin morphogenesis,biological_process
71606,GO:0035134,"The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.",post-embryonic dorsal fin morphogenesis,biological_process
71607,GO:0035135,"The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.",post-embryonic anal fin morphogenesis,biological_process
71608,GO:0035136,"The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.",forelimb morphogenesis,biological_process
71609,GO:0035137,The process in which the anatomical structures of the hindlimb are generated and organized.,hindlimb morphogenesis,biological_process
71610,GO:0035138,The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.,pectoral fin morphogenesis,biological_process
71611,GO:0035139,The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.,pelvic fin morphogenesis,biological_process
71612,GO:0035141,"The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.",medial fin morphogenesis,biological_process
71613,GO:0035142,The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.,dorsal fin morphogenesis,biological_process
71614,GO:0035143,"The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.",caudal fin morphogenesis,biological_process
71615,GO:0035144,"The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.",anal fin morphogenesis,biological_process
71616,GO:0035145,A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.,exon-exon junction complex,cellular_component
71617,GO:0035146,The joining of specific branches of a tubular system to form a continuous network.,tube fusion,biological_process
71618,GO:0035147,"Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.","branch fusion, open tracheal system",biological_process
71619,GO:0035148,Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.,tube formation,biological_process
71620,GO:0035149,Creation of the central hole of a tube in an open tracheal system through which gases flow.,"lumen formation, open tracheal system",biological_process
71621,GO:0035150,"Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.",regulation of tube size,biological_process
71622,GO:0035151,"Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.","regulation of tube size, open tracheal system",biological_process
71623,GO:0035152,Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.,"regulation of tube architecture, open tracheal system",biological_process
71624,GO:0035153,"Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.","epithelial cell type specification, open tracheal system",biological_process
71625,GO:0035154,"The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.","terminal cell fate specification, open tracheal system",biological_process
71626,GO:0035155,"Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.","negative regulation of terminal cell fate specification, open tracheal system",biological_process
71627,GO:0035156,"The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.",fusion cell fate specification,biological_process
71628,GO:0035157,"Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.",negative regulation of fusion cell fate specification,biological_process
71629,GO:0035158,Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.,"regulation of tube diameter, open tracheal system",biological_process
71630,GO:0035159,Ensuring that a tube in an open tracheal system is of the correct length.,"regulation of tube length, open tracheal system",biological_process
71631,GO:0035160,Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.,"maintenance of epithelial integrity, open tracheal system",biological_process
71632,GO:0035161,"Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.",imaginal disc lineage restriction,biological_process
71633,GO:0035162,The stages of blood cell formation that take place within the embryo.,embryonic hemopoiesis,biological_process
71634,GO:0035163,"The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.",embryonic hemocyte differentiation,biological_process
71635,GO:0035164,"The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.",embryonic plasmatocyte differentiation,biological_process
71636,GO:0035165,The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.,embryonic crystal cell differentiation,biological_process
71637,GO:0035166,The stages of blood cell formation that take place after completion of embryonic development.,post-embryonic hemopoiesis,biological_process
71638,GO:0035167,"The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.",larval lymph gland hemopoiesis,biological_process
71639,GO:0035168,"The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but n...",larval lymph gland hemocyte differentiation,biological_process
71640,GO:0035169,"The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.",lymph gland plasmatocyte differentiation,biological_process
71641,GO:0035170,The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.,lymph gland crystal cell differentiation,biological_process
71642,GO:0035171,"The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.",lamellocyte differentiation,biological_process
71643,GO:0035172,"The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.",hemocyte proliferation,biological_process
71644,GO:0035173,Catalysis of the transfer of a phosphate group to a histone.,histone kinase activity,molecular_function
71645,GO:0035175,Catalysis of the reaction: histone H3-serine (position 10) + ATP = histone H3-phosphoserine (position 10) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 10 of histone H3.,histone H3S10 kinase activity,molecular_function
71646,GO:0035176,"Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.",social behavior,biological_process
71647,GO:0035177,The movement of a larva through a feeding substrate whilst feeding on food.,larval foraging behavior,biological_process
71648,GO:0035178,"Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.",turning behavior,biological_process
71649,GO:0035180,"The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.",larval wandering behavior,biological_process
71650,GO:0035181,Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.,larval burrowing behavior,biological_process
71651,GO:0035182,"An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.",female germline ring canal outer rim,cellular_component
71652,GO:0035183,"A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.",female germline ring canal inner rim,cellular_component
71653,GO:0035185,"The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.",preblastoderm mitotic cell cycle,biological_process
71654,GO:0035186,"Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.",syncytial blastoderm mitotic cell cycle,biological_process
71655,GO:0035187,"The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.",hatching behavior,biological_process
71656,GO:0035188,The emergence of an immature organism from a protective structure.,hatching,biological_process
71657,GO:0035189,A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.,Rb-E2F complex,cellular_component
71658,GO:0035190,The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.,syncytial nuclear migration,biological_process
71659,GO:0035191,The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.,nuclear axial expansion,biological_process
71660,GO:0035192,"The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.",nuclear cortical migration,biological_process
71661,GO:0035193,"Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.",larval central nervous system remodeling,biological_process
71662,GO:0035194,"A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.",regulatory ncRNA-mediated post-transcriptional gene silencing,biological_process
71663,GO:0035195,"A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly...",miRNA-mediated post-transcriptional gene silencing,biological_process
71664,GO:0035196,"A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.",miRNA processing,biological_process
71665,GO:0035197,"Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.",siRNA binding,molecular_function
71666,GO:0035198,"Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.",miRNA binding,molecular_function
71667,GO:0035199,The specific avoidance actions or reactions of an organism in response to the perception of salt.,salt aversion,biological_process
71668,GO:0035200,"The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.",leg disc anterior/posterior pattern formation,biological_process
71669,GO:0035201,"Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.",leg disc anterior/posterior lineage restriction,biological_process
71670,GO:0035202,"Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.",tracheal pit formation in open tracheal system,biological_process
71671,GO:0035203,"Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.",regulation of lamellocyte differentiation,biological_process
71672,GO:0035204,"Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.",negative regulation of lamellocyte differentiation,biological_process
71673,GO:0035205,"Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.",positive regulation of lamellocyte differentiation,biological_process
71674,GO:0035206,"Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.",regulation of hemocyte proliferation,biological_process
71675,GO:0035207,"Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.",negative regulation of hemocyte proliferation,biological_process
71676,GO:0035208,"Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.",positive regulation of hemocyte proliferation,biological_process
71677,GO:0035209,"The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.",pupal development,biological_process
71678,GO:0035210,"The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.",prepupal development,biological_process
71679,GO:0035211,"The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.",spermathecum morphogenesis,biological_process
71680,GO:0035212,"Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.",cell competition in a multicellular organism,biological_process
71681,GO:0035213,"The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.",clypeo-labral disc development,biological_process
71682,GO:0035214,"Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.",eye-antennal disc development,biological_process
71683,GO:0035215,"Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming eit...",genital disc development,biological_process
71684,GO:0035216,"Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.",haltere disc development,biological_process
71685,GO:0035217,"Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.",labial disc development,biological_process
71686,GO:0035218,"Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.",leg disc development,biological_process
71687,GO:0035219,"Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.",prothoracic disc development,biological_process
71688,GO:0035220,"Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.",wing disc development,biological_process
71689,GO:0035221,The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.,genital disc pattern formation,biological_process
71690,GO:0035222,The process giving rise to the pattern of cell differentiation in the wing imaginal disc.,wing disc pattern formation,biological_process
71691,GO:0035223,The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.,leg disc pattern formation,biological_process
71692,GO:0035224,"The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).",genital disc anterior/posterior pattern formation,biological_process
71693,GO:0035225,"Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.",determination of genital disc primordium,biological_process
71694,GO:0035226,Binding to the catalytic subunit of glutamate-cysteine ligase.,glutamate-cysteine ligase catalytic subunit binding,molecular_function
71695,GO:0035230,"A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.",cytoneme,cellular_component
71696,GO:0035231,"Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.",cytoneme assembly,biological_process
71697,GO:0035232,"The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.",germ cell attraction,biological_process
71698,GO:0035233,"The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.",germ cell repulsion,biological_process
71699,GO:0035234,Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.,ectopic germ cell programmed cell death,biological_process
71700,GO:0035235,"The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.",ionotropic glutamate receptor signaling pathway,biological_process
71701,GO:0035236,"Combining with the neuropeptide proctolin, to initiate a change in cell activity.",proctolin receptor activity,molecular_function
71702,GO:0035237,Combining with the neuropeptide corazonin to initiate a change in cell activity.,corazonin receptor activity,molecular_function
71703,GO:0035238,"The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.",vitamin A biosynthetic process,biological_process
71704,GO:0035239,"The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.",tube morphogenesis,biological_process
71705,GO:0035240,"Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.",dopamine binding,molecular_function
71706,GO:0035241,Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.,protein-arginine omega-N monomethyltransferase activity,molecular_function
71707,GO:0035242,"Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.",protein-arginine omega-N asymmetric methyltransferase activity,molecular_function
71708,GO:0035243,"Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.",protein-arginine omega-N symmetric methyltransferase activity,molecular_function
71709,GO:0035244,Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein. This modification has been detected in anaerobic bacteria.,protein-arginine C-methyltransferase activity,molecular_function
71710,GO:0035246,The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein.,peptidyl-arginine N-methylation,biological_process
71711,GO:0035247,The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.,peptidyl-arginine omega-N-methylation,biological_process
71712,GO:0035248,Catalysis of the reaction: an N-acetyl-beta-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-beta-D-galactosaminyl derivative + UDP + H+.,"alpha-1,4-N-acetylgalactosaminyltransferase activity",molecular_function
71713,GO:0035249,"The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival...","synaptic transmission, glutamatergic",biological_process
71714,GO:0035250,Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule.,UDP-galactosyltransferase activity,molecular_function
71715,GO:0035251,Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.,UDP-glucosyltransferase activity,molecular_function
71716,GO:0035252,Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.,UDP-xylosyltransferase activity,molecular_function
71717,GO:0035253,"A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.",ciliary rootlet,cellular_component
71718,GO:0035254,Binding to a glutamate receptor.,glutamate receptor binding,molecular_function
71719,GO:0035255,Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.,ionotropic glutamate receptor binding,molecular_function
71720,GO:0035256,Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor).,G protein-coupled glutamate receptor binding,molecular_function
71721,GO:0035259,Binding to a nuclear glucocorticoid receptor.,nuclear glucocorticoid receptor binding,molecular_function
71722,GO:0035260,"The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.",internal genitalia morphogenesis,biological_process
71723,GO:0035261,"The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.",external genitalia morphogenesis,biological_process
71724,GO:0035262,"The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.",gonad morphogenesis,biological_process
71725,GO:0035263,"The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium de...",genital disc sexually dimorphic development,biological_process
71726,GO:0035264,"The increase in size or mass of an entire multicellular organism, as opposed to cell growth.",multicellular organism growth,biological_process
71727,GO:0035265,"The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.",organ growth,biological_process
71728,GO:0035266,"The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.",meristem growth,biological_process
71729,GO:0035267,"A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).",NuA4 histone acetyltransferase complex,cellular_component
71730,GO:0035269,"A glycoprotein biosynthetic process starting with the covalent linkage of a mannose via an alpha-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation via mannose,biological_process
71731,GO:0035270,"Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include ...",endocrine system development,biological_process
71732,GO:0035271,"Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.",ring gland development,biological_process
71733,GO:0035272,"Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.",exocrine system development,biological_process
71734,GO:0035273,"Binding to a phthalate, any ester or salt of phthalic acid.",phthalate binding,molecular_function
71735,GO:0035274,"Binding to diphenyl phthalate, C(20)H(14)O(4).",diphenyl phthalate binding,molecular_function
71736,GO:0035275,"Binding to dibutyl phthalate, C(16)H(22)O(4).",dibutyl phthalate binding,molecular_function
71737,GO:0035276,"Binding to ethanol, CH(3)-CH(2)-OH.",ethanol binding,molecular_function
71738,GO:0035277,The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.,"spiracle morphogenesis, open tracheal system",biological_process
71739,GO:0035278,"An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.",miRNA-mediated gene silencing by inhibition of translation,biological_process
71740,GO:0035279,"An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.",miRNA-mediated gene silencing by mRNA destabilization,biological_process
71741,GO:0035281,"Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.",pre-miRNA export from nucleus,biological_process
71742,GO:0035282,"The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.",segmentation,biological_process
71743,GO:0035283,Division of the central nervous system into a series of semi-repetitive parts or segments.,central nervous system segmentation,biological_process
71744,GO:0035284,Division of the brain into a series of semi-repetitive parts or segments.,brain segmentation,biological_process
71745,GO:0035285,"Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.",appendage segmentation,biological_process
71746,GO:0035287,"Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).",head segmentation,biological_process
71747,GO:0035288,"Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.",anterior head segmentation,biological_process
71748,GO:0035289,"Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.",posterior head segmentation,biological_process
71749,GO:0035290,"Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.",trunk segmentation,biological_process
71750,GO:0035291,"The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.","specification of segmental identity, intercalary segment",biological_process
71751,GO:0035292,"The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.","specification of segmental identity, trunk",biological_process
71752,GO:0035293,The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.,chitin-based larval cuticle pattern formation,biological_process
71753,GO:0035294,"Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.",determination of wing disc primordium,biological_process
71754,GO:0035295,"The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.",tube development,biological_process
71755,GO:0035296,Any process that modulates the diameter of a tube.,regulation of tube diameter,biological_process
71756,GO:0035297,"Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producing tubes with a cirumference of two cells.",regulation of Malpighian tubule diameter,biological_process
71757,GO:0035298,Ensuring that a Malpighian tubule is the correct length and diameter.,regulation of Malpighian tubule size,biological_process
71758,GO:0035299,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H+.","inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity",molecular_function
71759,GO:0035301,"A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).",Hedgehog signaling complex,cellular_component
71760,GO:0035302,Catalysis of the hydroxylation of an ecdysteroid at carbon position 25.,ecdysteroid 25-hydroxylase activity,molecular_function
71761,GO:0035303,"Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.",regulation of dephosphorylation,biological_process
71762,GO:0035305,"Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.",negative regulation of dephosphorylation,biological_process
71763,GO:0035306,"Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.",positive regulation of dephosphorylation,biological_process
71764,GO:0035309,"The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.",wing and notum subfield formation,biological_process
71765,GO:0035310,"The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.",notum cell fate specification,biological_process
71766,GO:0035311,"The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.",wing cell fate specification,biological_process
71767,GO:0035312,Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.,5'-3' DNA exonuclease activity,molecular_function
71768,GO:0035313,The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.,"wound healing, spreading of epidermal cells",biological_process
71769,GO:0035314,"Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.",scab formation,biological_process
71770,GO:0035315,The process in which a relatively unspecialized cell acquires specialized features of a hair cell.,hair cell differentiation,biological_process
71771,GO:0035316,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.",non-sensory hair organization,biological_process
71772,GO:0035317,"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.",imaginal disc-derived wing hair organization,biological_process
71773,GO:0035318,"Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.",imaginal disc-derived wing hair outgrowth,biological_process
71774,GO:0035319,Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.,imaginal disc-derived wing hair elongation,biological_process
71775,GO:0035320,Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.,imaginal disc-derived wing hair site selection,biological_process
71776,GO:0035321,"Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.",maintenance of imaginal disc-derived wing hair orientation,biological_process
71777,GO:0035323,An intercellular bridge that connects the germline cells of a male cyst.,male germline ring canal,cellular_component
71778,GO:0035324,An intercellular bridge that connects the germline cells of a female cyst.,female germline ring canal,cellular_component
71779,GO:0035325,"Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.",Toll-like receptor binding,molecular_function
71780,GO:0035329,"An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation.",hippo signaling,biological_process
71781,GO:0035330,"Any process that modulates the frequency, rate or extent of hippo signaling.",regulation of hippo signaling,biological_process
71782,GO:0035331,"Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.",negative regulation of hippo signaling,biological_process
71783,GO:0035332,"Any process that activates or increases the frequency, rate or extent of hippo signaling.",positive regulation of hippo signaling,biological_process
71784,GO:0035333,"The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).","Notch receptor processing, ligand-dependent",biological_process
71785,GO:0035334,"The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.","Notch receptor processing, ligand-independent",biological_process
71786,GO:0035335,The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.,peptidyl-tyrosine dephosphorylation,biological_process
71787,GO:0035336,"The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty-acyl-CoA metabolic process,biological_process
71788,GO:0035337,"The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.",fatty-acyl-CoA metabolic process,biological_process
71789,GO:0035338,The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty-acyl-CoA biosynthetic process,biological_process
71790,GO:0035340,"The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",inosine transport,biological_process
71791,GO:0035341,"Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of inosine transport,biological_process
71792,GO:0035342,"Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of inosine transport,biological_process
71793,GO:0035343,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of inosine transport,biological_process
71794,GO:0035344,"The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hypoxanthine transport,biological_process
71795,GO:0035345,"Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of hypoxanthine transport,biological_process
71796,GO:0035346,"Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of hypoxanthine transport,biological_process
71797,GO:0035347,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of hypoxanthine transport,biological_process
71798,GO:0035348,"The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.",acetyl-CoA transmembrane transport,biological_process
71799,GO:0035349,"The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A transmembrane transport,biological_process
71800,GO:0035350,"The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.",FAD transmembrane transport,biological_process
71801,GO:0035351,"The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.",heme transmembrane transport,biological_process
71802,GO:0035352,"The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.",NAD transmembrane transport,biological_process
71803,GO:0035353,"The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.",nicotinamide mononucleotide transmembrane transport,biological_process
71804,GO:0035354,A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).,Toll-like receptor 1-Toll-like receptor 2 protein complex,cellular_component
71805,GO:0035355,A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).,Toll-like receptor 2-Toll-like receptor 6 protein complex,cellular_component
71806,GO:0035356,A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell.,intracellular triglyceride homeostasis,biological_process
71807,GO:0035357,"A nuclear receptor-mediated signaling pathway initiated by a ligand binding to an intracellular peroxisome proliferator activated receptor (alpha, beta or gamma) of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",peroxisome proliferator activated receptor signaling pathway,biological_process
71808,GO:0035358,"Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.",regulation of peroxisome proliferator activated receptor signaling pathway,biological_process
71809,GO:0035359,"Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.",negative regulation of peroxisome proliferator activated receptor signaling pathway,biological_process
71810,GO:0035360,"Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.",positive regulation of peroxisome proliferator activated receptor signaling pathway,biological_process
71811,GO:0035361,"A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.",Cul8-RING ubiquitin ligase complex,cellular_component
71812,GO:0035362,"The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.",protein-DNA ISRE complex assembly,biological_process
71813,GO:0035363,"A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.",histone locus body,cellular_component
71814,GO:0035364,"The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",thymine transport,biological_process
71815,GO:0035365,"Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of thymine transport,biological_process
71816,GO:0035366,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of thymine transport,biological_process
71817,GO:0035367,"Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of thymine transport,biological_process
71818,GO:0035368,"Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.",selenocysteine insertion sequence binding,molecular_function
71819,GO:0035369,"An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",pre-B cell receptor complex,cellular_component
71820,GO:0035371,"The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.",microtubule plus-end,cellular_component
71821,GO:0035372,"A process in which a protein is transported to, or maintained at, a microtubule.",protein localization to microtubule,biological_process
71822,GO:0035373,"Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.",chondroitin sulfate proteoglycan binding,molecular_function
71823,GO:0035374,"Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).",chondroitin sulfate binding,molecular_function
71824,GO:0035375,"Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.",zymogen binding,molecular_function
71825,GO:0035376,The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.,sterol import,biological_process
71826,GO:0035377,The directed movement of water (H2O) from one side of an epithelium to the other.,transepithelial water transport,biological_process
71827,GO:0035378,The process in which carbon dioxide (CO2) is transported across a membrane.,carbon dioxide transmembrane transport,biological_process
71828,GO:0035379,Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.,carbon dioxide transmembrane transporter activity,molecular_function
71829,GO:0035380,"Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.",very long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase activity,molecular_function
71830,GO:0035381,Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.,ATP-gated ion channel activity,molecular_function
71831,GO:0035382,The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.,sterol transmembrane transport,biological_process
71832,GO:0035385,"The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",Roundabout signaling pathway,biological_process
71833,GO:0035386,"Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.",regulation of Roundabout signaling pathway,biological_process
71834,GO:0035387,"Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.",negative regulation of Roundabout signaling pathway,biological_process
71835,GO:0035388,"Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.",positive regulation of Roundabout signaling pathway,biological_process
71836,GO:0035393,"The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 9 production,biological_process
71837,GO:0035394,"Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.",regulation of chemokine (C-X-C motif) ligand 9 production,biological_process
71838,GO:0035395,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.",negative regulation of chemokine (C-X-C motif) ligand 9 production,biological_process
71839,GO:0035396,"Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.",positive regulation of chemokine (C-X-C motif) ligand 9 production,biological_process
71840,GO:0035397,Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.,helper T cell enhancement of adaptive immune response,biological_process
71841,GO:0035398,Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.,helper T cell enhancement of T cell mediated immune response,biological_process
71842,GO:0035399,Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.,helper T cell enhancement of B cell mediated immune response,biological_process
71843,GO:0035401,Catalysis of the reaction: histone H3-tyrosine (position 41) + ATP = histone H3-phosphotyrosine (position 41) + ADP. This reaction is the addition of a phosphate group to the tyrosine residue at position 41 of histone H3.,histone H3Y41 kinase activity,molecular_function
71844,GO:0035402,Catalysis of the reaction: histone H3-threonine (position 11) + ATP = histone H3-phosphothreonine (position 11) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 11 of histone H3.,histone H3T11 kinase activity,molecular_function
71845,GO:0035403,Catalysis of the reaction: histone H3-threonine (position 6) + ATP = histone H3-phosphothreonine (position 6) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 6 of histone H3.,histone H3T6 kinase activity,molecular_function
71846,GO:0035418,"Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.",protein localization to synapse,biological_process
71847,GO:0035425,"Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.",autocrine signaling,biological_process
71848,GO:0035426,Any process that mediates the transfer of information between the extracellular matrix and a cell.,extracellular matrix-cell signaling,biological_process
71849,GO:0035429,The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.,gluconate transmembrane transport,biological_process
71850,GO:0035430,"Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.",regulation of gluconate transmembrane transport,biological_process
71851,GO:0035431,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.",negative regulation of gluconate transmembrane transport,biological_process
71852,GO:0035432,"Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.",positive regulation of gluconate transmembrane transport,biological_process
71853,GO:0035433,The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.,acetate transmembrane transport,biological_process
71854,GO:0035434,The directed movement of copper cation across a membrane.,copper ion transmembrane transport,biological_process
71855,GO:0035435,The process in which a phosphate is transported across a membrane.,phosphate ion transmembrane transport,biological_process
71856,GO:0035436,The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.,triose phosphate transmembrane transport,biological_process
71857,GO:0035437,"Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.",maintenance of protein localization in endoplasmic reticulum,biological_process
71858,GO:0035438,"Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate.",cyclic-di-GMP binding,molecular_function
71859,GO:0035439,"Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.",halimadienyl-diphosphate synthase activity,molecular_function
71860,GO:0035440,"The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.",tuberculosinol biosynthetic process,biological_process
71861,GO:0035441,The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.,cell migration involved in vasculogenesis,biological_process
71862,GO:0035442,The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.,dipeptide transmembrane transport,biological_process
71863,GO:0035443,The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.,tripeptide transmembrane transport,biological_process
71864,GO:0035444,The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.,nickel cation transmembrane transport,biological_process
71865,GO:0035445,"The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.",borate transmembrane transport,biological_process
71866,GO:0035446,"Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.",cysteine-glucosaminylinositol ligase activity,molecular_function
71867,GO:0035447,Catalysis of the reaction: 1D-myo-inositol-2-(L-cysteinylamido)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coA + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.,mycothiol synthase activity,molecular_function
71868,GO:0035448,"The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of thylakoid membrane,cellular_component
71869,GO:0035449,"The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of plastid thylakoid membrane,cellular_component
71870,GO:0035450,"The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.",extrinsic component of lumenal side of plastid thylakoid membrane,cellular_component
71871,GO:0035451,"The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.",extrinsic component of stromal side of plastid thylakoid membrane,cellular_component
71872,GO:0035452,"The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of plastid membrane,cellular_component
71873,GO:0035453,"The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of plastid inner membrane,cellular_component
71874,GO:0035454,"The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.",extrinsic component of stromal side of plastid inner membrane,cellular_component
71875,GO:0035455,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.",response to interferon-alpha,biological_process
71876,GO:0035456,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.",response to interferon-beta,biological_process
71877,GO:0035457,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.",cellular response to interferon-alpha,biological_process
71878,GO:0035458,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.",cellular response to interferon-beta,biological_process
71879,GO:0035459,The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.,vesicle cargo loading,biological_process
71880,GO:0035460,Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.,L-ascorbate 6-phosphate lactonase activity,molecular_function
71881,GO:0035461,The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.,vitamin transmembrane transport,biological_process
71882,GO:0035462,The establishment of the diencephalon with respect to the left and right halves.,determination of left/right asymmetry in diencephalon,biological_process
71883,GO:0035469,Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.,determination of pancreatic left/right asymmetry,biological_process
71884,GO:0035470,"Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.",positive regulation of vascular wound healing,biological_process
71885,GO:0035471,"The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.",luteinizing hormone signaling pathway involved in ovarian follicle development,biological_process
71886,GO:0035472,Combining with the choriogonadotropin hormone to initiate a change in cell activity.,choriogonadotropin hormone receptor activity,molecular_function
71887,GO:0035473,Binding to a lipase.,lipase binding,molecular_function
71888,GO:0035474,The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.,selective angioblast sprouting,biological_process
71889,GO:0035475,"The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.",angioblast cell migration involved in selective angioblast sprouting,biological_process
71890,GO:0035476,"The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.",angioblast cell migration,biological_process
71891,GO:0035477,"Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.",regulation of angioblast cell migration involved in selective angioblast sprouting,biological_process
71892,GO:0035478,"Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.",chylomicron binding,molecular_function
71893,GO:0035479,The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.,angioblast cell migration from lateral mesoderm to midline,biological_process
71894,GO:0035482,"The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.",gastric motility,biological_process
71895,GO:0035483,The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.,gastric emptying,biological_process
71896,GO:0035484,Binding to a double-stranded DNA region containing an A/A mispair.,adenine/adenine mispair binding,molecular_function
71897,GO:0035485,Binding to a double-stranded DNA region containing an A/G mispair.,adenine/guanine mispair binding,molecular_function
71898,GO:0035486,Binding to a double-stranded DNA region containing a C/C mispair.,cytosine/cytosine mispair binding,molecular_function
71899,GO:0035487,Binding to a double-stranded DNA region containing a T/T mispair.,thymine/thymine mispair binding,molecular_function
71900,GO:0035488,Binding to a double-stranded DNA region containing a C/T mispair.,cytosine/thymine mispair binding,molecular_function
71901,GO:0035489,Binding to a double-stranded DNA region containing a G/G mispair.,guanine/guanine mispair binding,molecular_function
71902,GO:0035490,"Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.",regulation of leukotriene production involved in inflammatory response,biological_process
71903,GO:0035491,"Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.",positive regulation of leukotriene production involved in inflammatory response,biological_process
71904,GO:0035493,"The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",SNARE complex assembly,biological_process
71905,GO:0035494,"The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",SNARE complex disassembly,biological_process
71906,GO:0035495,"Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",regulation of SNARE complex disassembly,biological_process
71907,GO:0035496,"Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.","lipopolysaccharide-1,5-galactosyltransferase activity",molecular_function
71908,GO:0035497,"Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.",cAMP response element binding,molecular_function
71909,GO:0035498,The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).,carnosine metabolic process,biological_process
71910,GO:0035499,The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).,carnosine biosynthetic process,biological_process
71911,GO:0035500,Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.,MH2 domain binding,molecular_function
71912,GO:0035501,Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.,MH1 domain binding,molecular_function
71913,GO:0035502,The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.,metanephric part of ureteric bud development,biological_process
71914,GO:0035503,The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.,ureter part of ureteric bud development,biological_process
71915,GO:0035510,The removal of an alkyl group from one or more nucleotides within an DNA molecule.,DNA dealkylation,biological_process
71916,GO:0035513,The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.,oxidative RNA demethylation,biological_process
71917,GO:0035514,Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.,DNA demethylase activity,molecular_function
71918,GO:0035515,Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.,oxidative RNA demethylase activity,molecular_function
71919,GO:0035516,"Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2. Catalyzes oxidative demethylation of the DNA base lesions N1- methyladenine, N3-methylcytosine, N1-methylguanine, and N3- methylthymine. Can also act of RNA.",broad specificity oxidative DNA demethylase activity,molecular_function
71920,GO:0035517,"A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.",PR-DUB complex,cellular_component
71921,GO:0035519,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.",protein K29-linked ubiquitination,biological_process
71922,GO:0035520,The removal of the ubiquitin group from a monoubiquitinated protein.,monoubiquitinated protein deubiquitination,biological_process
71923,GO:0035523,"A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.",protein K29-linked deubiquitination,biological_process
71924,GO:0035524,"The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.",proline transmembrane transport,biological_process
71925,GO:0035525,A heterodimer of NF-kappa B p50 and p65 subunits.,NF-kappaB p50/p65 complex,cellular_component
71926,GO:0035526,"The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.","retrograde transport, plasma membrane to Golgi",biological_process
71927,GO:0035527,Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.,3-hydroxypropionate dehydrogenase (NADP+) activity,molecular_function
71928,GO:0035529,Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.,NADH pyrophosphatase activity,molecular_function
71929,GO:0035530,"The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 6 production,biological_process
71930,GO:0035531,"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).",regulation of chemokine (C-C motif) ligand 6 production,biological_process
71931,GO:0035532,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).",negative regulation of chemokine (C-C motif) ligand 6 production,biological_process
71932,GO:0035533,"Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).",positive regulation of chemokine (C-C motif) ligand 6 production,biological_process
71933,GO:0035538,"Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.",carbohydrate response element binding,molecular_function
71934,GO:0035539,"Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.","8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity",molecular_function
71935,GO:0035540,"Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",positive regulation of SNARE complex disassembly,biological_process
71936,GO:0035541,"Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",negative regulation of SNARE complex disassembly,biological_process
71937,GO:0035542,"Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",regulation of SNARE complex assembly,biological_process
71938,GO:0035543,"Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",positive regulation of SNARE complex assembly,biological_process
71939,GO:0035544,"Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.",negative regulation of SNARE complex assembly,biological_process
71940,GO:0035545,The establishment of the nervous system with respect to the left and right halves.,determination of left/right asymmetry in nervous system,biological_process
71941,GO:0035550,A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).,urease complex,cellular_component
71942,GO:0035554,"The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.",termination of Roundabout signal transduction,biological_process
71943,GO:0035556,"The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.",intracellular signal transduction,biological_process
71944,GO:0035560,"Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.",pheophorbidase activity,molecular_function
71945,GO:0035562,"Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.",negative regulation of chromatin binding,biological_process
71946,GO:0035563,"Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.",positive regulation of chromatin binding,biological_process
71947,GO:0035564,Any process that modulates the size of a kidney.,regulation of kidney size,biological_process
71948,GO:0035565,Any process that modulates the size of a pronephric kidney.,regulation of pronephros size,biological_process
71949,GO:0035566,Any process that modulates the size of a metanephric kidney.,regulation of metanephros size,biological_process
71950,GO:0035567,A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via effectors other than beta-catenin.,non-canonical Wnt signaling pathway,biological_process
71951,GO:0035572,"The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.",N-terminal peptidyl-serine dimethylation,biological_process
71952,GO:0035573,"The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.",N-terminal peptidyl-serine trimethylation,biological_process
71953,GO:0035575,Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H4K20 demethylase activity,molecular_function
71954,GO:0035577,"The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.",azurophil granule membrane,cellular_component
71955,GO:0035578,"The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.",azurophil granule lumen,cellular_component
71956,GO:0035579,"The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.",specific granule membrane,cellular_component
71957,GO:0035580,"The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.",specific granule lumen,cellular_component
71958,GO:0035588,"A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.",G protein-coupled purinergic receptor signaling pathway,biological_process
71959,GO:0035589,"A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process.",G protein-coupled purinergic nucleotide receptor signaling pathway,biological_process
71960,GO:0035590,"The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",purinergic nucleotide receptor signaling pathway,biological_process
71961,GO:0035591,"The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.",signaling adaptor activity,molecular_function
71962,GO:0035592,The directed movement of a protein to a specific location within the extracellular region.,establishment of protein localization to extracellular region,biological_process
71963,GO:0035594,"Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.",ganglioside binding,molecular_function
71964,GO:0035595,Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.,N-acetylglucosaminylinositol deacetylase activity,molecular_function
71965,GO:0035596,Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.,methylthiotransferase activity,molecular_function
71966,GO:0035597,Catalysis of the reaction: N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H+.,tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity,molecular_function
71967,GO:0035598,Catalysis of the reaction: N(6)-L-threonylcarbamoyladenosine(37) in tRNA + [sulfur carrier]-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + [sulfur carrier]-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H+.,tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity,molecular_function
71968,GO:0035599,Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.,aspartic acid methylthiotransferase activity,molecular_function
71969,GO:0035600,The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.,tRNA methylthiolation,biological_process
71970,GO:0035601,"The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.",protein deacylation,biological_process
71971,GO:0035602,"The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.",fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell,biological_process
71972,GO:0035603,"The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.",fibroblast growth factor receptor signaling pathway involved in hemopoiesis,biological_process
71973,GO:0035604,"The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.",fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow,biological_process
71974,GO:0035605,Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.,peptidyl-cysteine S-nitrosylase activity,molecular_function
71975,GO:0035606,Transfer of a nitric oxide (NO) group from one cysteine residue to another.,peptidyl-cysteine S-trans-nitrosylation,biological_process
71976,GO:0035607,"The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.",fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development,biological_process
71977,GO:0035608,"The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.",protein deglutamylation,biological_process
71978,GO:0035609,"The removal of a C-terminal, gene-encoded glutamate residue from a protein.",C-terminal protein deglutamylation,biological_process
71979,GO:0035610,The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.,protein side chain deglutamylation,biological_process
71980,GO:0035612,"Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).",AP-2 adaptor complex binding,molecular_function
71981,GO:0035613,Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.,RNA stem-loop binding,molecular_function
71982,GO:0035614,Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.,snRNA stem-loop binding,molecular_function
71983,GO:0035615,"Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.",clathrin-cargo adaptor activity,molecular_function
71984,GO:0035617,The disaggregation of a cytoplasmic stress granule into its constituent protein and RNA parts.,cytoplasmic stress granule disassembly,biological_process
71985,GO:0035618,"A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.",root hair,cellular_component
71986,GO:0035619,The tip portion of an outgrowth of a root epidermal cell.,root hair tip,cellular_component
71987,GO:0035621,The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.,ER to Golgi ceramide transport,biological_process
71988,GO:0035622,"The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).",intrahepatic bile duct development,biological_process
71989,GO:0035623,"A renal system process in which D-glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.",renal D-glucose absorption,biological_process
71990,GO:0035626,"The series of molecular signals initiated by a juvenile hormone binding to its receptor, a bHLH-PAS transcription factor, to regulate gene expression.",juvenile hormone mediated signaling pathway,biological_process
71991,GO:0035627,"The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.",ceramide transport,biological_process
71992,GO:0035628,"The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct.",cystic duct development,biological_process
71993,GO:0035630,"The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.",bone mineralization involved in bone maturation,biological_process
71994,GO:0035631,"A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.",CD40 receptor complex,cellular_component
71995,GO:0035632,"A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence,...",mitochondrial prohibitin complex,cellular_component
71996,GO:0035633,"Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.",maintenance of blood-brain barrier,biological_process
71997,GO:0035634,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.",response to stilbenoid,biological_process
71998,GO:0035635,The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,entry of bacterium into host cell,biological_process
71999,GO:0035639,"Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.",purine ribonucleoside triphosphate binding,molecular_function
72000,GO:0035640,The specific behavior of an organism in response to a novel environment or stimulus.,exploration behavior,biological_process
72001,GO:0035641,The specific movement from place to place of an organism in response to a novel environment.,locomotory exploration behavior,biological_process
72002,GO:0035642,Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.,histone H3R17 methyltransferase activity,molecular_function
72003,GO:0035643,"Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.",L-DOPA receptor activity,molecular_function
72004,GO:0035644,The process of removing one or more phosphate groups from a phosphorylated anandamide.,phosphoanandamide dephosphorylation,biological_process
72005,GO:0035645,The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.,enteric smooth muscle cell differentiation,biological_process
72006,GO:0035646,"The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.",endosome to melanosome transport,biological_process
72007,GO:0035648,The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.,circadian mating behavior,biological_process
72008,GO:0035649,"A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.",Nrd1 complex,cellular_component
72009,GO:0035650,"Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).",AP-1 adaptor complex binding,molecular_function
72010,GO:0035651,"Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).",AP-3 adaptor complex binding,molecular_function
72011,GO:0035652,Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.,clathrin-coated vesicle cargo loading,biological_process
72012,GO:0035653,"Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.","clathrin-coated vesicle cargo loading, AP-1-mediated",biological_process
72013,GO:0035654,"Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.","clathrin-coated vesicle cargo loading, AP-3-mediated",biological_process
72014,GO:0035655,"The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-18-mediated signaling pathway,biological_process
72015,GO:0035657,"A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.",eRF1 methyltransferase complex,cellular_component
72016,GO:0035658,"A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.",Mon1-Ccz1 complex,cellular_component
72017,GO:0035660,"The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.",MyD88-dependent toll-like receptor 4 signaling pathway,biological_process
72018,GO:0035661,The series of molecular signals initiated by a ligand binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.,MyD88-dependent toll-like receptor 2 signaling pathway,biological_process
72019,GO:0035662,"Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.",Toll-like receptor 4 binding,molecular_function
72020,GO:0035663,"Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.",Toll-like receptor 2 binding,molecular_function
72021,GO:0035664,The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.,TIRAP-dependent toll-like receptor signaling pathway,biological_process
72022,GO:0035665,The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.,TIRAP-dependent toll-like receptor 4 signaling pathway,biological_process
72023,GO:0035666,The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.,TRIF-dependent toll-like receptor signaling pathway,biological_process
72024,GO:0035667,The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.,TRIF-dependent toll-like receptor 4 signaling pathway,biological_process
72025,GO:0035668,The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.,TRAM-dependent toll-like receptor signaling pathway,biological_process
72026,GO:0035669,The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.,TRAM-dependent toll-like receptor 4 signaling pathway,biological_process
72027,GO:0035670,"The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.",plant-type ovary development,biological_process
72028,GO:0035671,Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.,enone reductase activity,molecular_function
72029,GO:0035672,The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.,oligopeptide transmembrane transport,biological_process
72030,GO:0035673,Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.,oligopeptide transmembrane transporter activity,molecular_function
72031,GO:0035674,The process in which a tricarboxylic acid is transported across a membrane.,tricarboxylic acid transmembrane transport,biological_process
72032,GO:0035675,"The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.",neuromast hair cell development,biological_process
72033,GO:0035676,"The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.",anterior lateral line neuromast hair cell development,biological_process
72034,GO:0035677,"The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.",posterior lateral line neuromast hair cell development,biological_process
72035,GO:0035678,The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.,neuromast hair cell morphogenesis,biological_process
72036,GO:0035679,The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.,anterior lateral line neuromast hair cell morphogenesis,biological_process
72037,GO:0035680,The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.,posterior lateral line neuromast hair cell morphogenesis,biological_process
72038,GO:0035681,The series of molecular signals initiated by a ligand binding to toll-like receptor 15.,toll-like receptor 15 signaling pathway,biological_process
72039,GO:0035682,The series of molecular signals initiated by a ligand binding to toll-like receptor 21.,toll-like receptor 21 signaling pathway,biological_process
72040,GO:0035683,The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.,memory T cell extravasation,biological_process
72041,GO:0035684,The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.,helper T cell extravasation,biological_process
72042,GO:0035685,"The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.",helper T cell diapedesis,biological_process
72043,GO:0035686,"A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.",sperm fibrous sheath,cellular_component
72044,GO:0035687,"The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.",T-helper 1 cell extravasation,biological_process
72045,GO:0035688,"The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.",T-helper 1 cell diapedesis,biological_process
72046,GO:0035689,"The series of molecular signals initiated by chemokine CCL5 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine (C-C motif) ligand 5 signaling pathway,biological_process
72047,GO:0035691,"The series of molecular signals initiated by macrophage migration inhibitory factor binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",macrophage migration inhibitory factor signaling pathway,biological_process
72048,GO:0035692,A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.,macrophage migration inhibitory factor receptor complex,cellular_component
72049,GO:0035693,A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.,NOS2-CD74 complex,cellular_component
72050,GO:0035694,The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.,mitochondrial protein catabolic process,biological_process
72051,GO:0035695,The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.,mitophagy by internal vacuole formation,biological_process
72052,GO:0035696,The migration of a monocyte from the blood vessels into the surrounding tissue.,monocyte extravasation,biological_process
72053,GO:0035697,"The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.","CD8-positive, alpha-beta T cell extravasation",biological_process
72054,GO:0035698,"The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.","CD8-positive, alpha-beta cytotoxic T cell extravasation",biological_process
72055,GO:0035699,The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.,T-helper 17 cell extravasation,biological_process
72056,GO:0035700,The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,astrocyte chemotaxis,biological_process
72057,GO:0035701,"The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.",hematopoietic stem cell migration,biological_process
72058,GO:0035702,The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.,monocyte homeostasis,biological_process
72059,GO:0035703,The movement of a monocyte from the bone marrow to the blood stream.,monocyte migration into blood stream,biological_process
72060,GO:0035704,The directed movement of a helper T cell in response to an external stimulus.,helper T cell chemotaxis,biological_process
72061,GO:0035705,The directed movement of a T-helper 17 cell in response to an external stimulus.,T-helper 17 cell chemotaxis,biological_process
72062,GO:0035706,The directed movement of a T-helper 1 cell in response to an external stimulus.,T-helper 1 cell chemotaxis,biological_process
72063,GO:0035707,The directed movement of a T-helper 2 cell in response to an external stimulus.,T-helper 2 cell chemotaxis,biological_process
72064,GO:0035708,"The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).",interleukin-4-dependent isotype switching to IgE isotypes,biological_process
72065,GO:0035709,"The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",memory T cell activation,biological_process
72066,GO:0035710,"The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.","CD4-positive, alpha-beta T cell activation",biological_process
72067,GO:0035711,"The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",T-helper 1 cell activation,biological_process
72068,GO:0035712,"The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",T-helper 2 cell activation,biological_process
72069,GO:0035713,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.",response to nitrogen dioxide,biological_process
72070,GO:0035714,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.",cellular response to nitrogen dioxide,biological_process
72071,GO:0035715,Binding to chemokine (C-C motif) ligand 2.,chemokine (C-C motif) ligand 2 binding,molecular_function
72072,GO:0035716,Binding to chemokine (C-C motif) ligand 12.,chemokine (C-C motif) ligand 12 binding,molecular_function
72073,GO:0035717,Binding to chemokine (C-C motif) ligand 7.,chemokine (C-C motif) ligand 7 binding,molecular_function
72074,GO:0035718,"Binding to the cytokine, macrophage migration inhibitory factor.",macrophage migration inhibitory factor binding,molecular_function
72075,GO:0035719,The directed movement of tRNA from the cytoplasm to the nucleus.,tRNA import into nucleus,biological_process
72076,GO:0035720,"The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.",intraciliary anterograde transport,biological_process
72077,GO:0035721,"The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.",intraciliary retrograde transport,biological_process
72078,GO:0035722,"The series of molecular signals initiated by interleukin-12 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-12-mediated signaling pathway,biological_process
72079,GO:0035723,"The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-15-mediated signaling pathway,biological_process
72080,GO:0035725,A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,sodium ion transmembrane transport,biological_process
72081,GO:0035726,"The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.",common myeloid progenitor cell proliferation,biological_process
72082,GO:0035727,"Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.",lysophosphatidic acid binding,molecular_function
72083,GO:0035728,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.",response to hepatocyte growth factor,biological_process
72084,GO:0035729,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.",cellular response to hepatocyte growth factor stimulus,biological_process
72085,GO:0035730,"Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.",S-nitrosoglutathione binding,molecular_function
72086,GO:0035731,"Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.",dinitrosyl-iron complex binding,molecular_function
72087,GO:0035732,"The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.",nitric oxide storage,biological_process
72088,GO:0035733,"A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.",hepatic stellate cell activation,biological_process
72089,GO:0035735,The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.,intraciliary transport involved in cilium assembly,biological_process
72090,GO:0035736,"The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.",cell proliferation involved in compound eye morphogenesis,biological_process
72091,GO:0035738,A process by which an organism alters or subverts a biological process in another organism via the action of a venom. Venoms are injected into the prey by a bite or a sting. Venoms cause their biological effects via the many toxins that they contain; some venoms are complex mixtures of toxins of differing types. Venoms can serve as predation mechanisms or defense responses.,venom-mediated perturbation of biological process,biological_process
72092,GO:0035739,"The expansion of a CD4-positive, alpha-beta T cell population by cell division.","CD4-positive, alpha-beta T cell proliferation",biological_process
72093,GO:0035740,"The expansion of a CD8-positive, alpha-beta T cell population by cell division.","CD8-positive, alpha-beta T cell proliferation",biological_process
72094,GO:0035741,"The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.","activated CD4-positive, alpha-beta T cell proliferation",biological_process
72095,GO:0035742,"The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.","activated CD8-positive, alpha-beta T cell proliferation",biological_process
72096,GO:0035743,"Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.","CD4-positive, alpha-beta T cell cytokine production",biological_process
72097,GO:0035744,Any process that contributes to cytokine production by a T-helper 1 cell.,T-helper 1 cell cytokine production,biological_process
72098,GO:0035745,Any process that contributes to cytokine production by a T-helper 2 cell.,T-helper 2 cell cytokine production,biological_process
72099,GO:0035746,"The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",granzyme A production,biological_process
72100,GO:0035747,The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,natural killer cell chemotaxis,biological_process
72101,GO:0035748,The region of the myelin sheath furthest from the axon.,myelin sheath abaxonal region,cellular_component
72102,GO:0035749,The region of the myelin sheath nearest to the axon.,myelin sheath adaxonal region,cellular_component
72103,GO:0035750,"Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.",protein localization to myelin sheath abaxonal region,biological_process
72104,GO:0035752,"Any process that increases the pH of the lysosomal lumen, corresponding to a decrease in hydrogen ion concentration.",lysosomal lumen pH elevation,biological_process
72105,GO:0035753,Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.,maintenance of DNA trinucleotide repeats,biological_process
72106,GO:0035754,The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,B cell chemotaxis,biological_process
72107,GO:0035755,"Catalysis of the reaction: a cardiolipin + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+).",cardiolipin phospholipase D activity,molecular_function
72108,GO:0035756,A process in which a symbiont moves from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated migration across host transepithelium,biological_process
72109,GO:0035757,Binding to chemokine (C-C motif) ligand 19.,chemokine (C-C motif) ligand 19 binding,molecular_function
72110,GO:0035758,Binding to chemokine (C-C motif) ligand 21.,chemokine (C-C motif) ligand 21 binding,molecular_function
72111,GO:0035759,The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.,mesangial cell-matrix adhesion,biological_process
72112,GO:0035760,"The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.",cytoplasmic polyadenylation-dependent rRNA catabolic process,biological_process
72113,GO:0035761,"A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.",dorsal motor nucleus of vagus nerve maturation,biological_process
72114,GO:0035762,The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.,dorsal motor nucleus of vagus nerve morphogenesis,biological_process
72115,GO:0035763,The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.,dorsal motor nucleus of vagus nerve structural organization,biological_process
72116,GO:0035764,The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.,dorsal motor nucleus of vagus nerve formation,biological_process
72117,GO:0035766,The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).,cell chemotaxis to fibroblast growth factor,biological_process
72118,GO:0035767,The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,endothelial cell chemotaxis,biological_process
72119,GO:0035768,The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).,endothelial cell chemotaxis to fibroblast growth factor,biological_process
72120,GO:0035769,The movement of a B cell to cross a high endothelial venule in response to an external stimulus.,B cell chemotaxis across high endothelial venule,biological_process
72121,GO:0035770,"A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.",ribonucleoprotein granule,cellular_component
72122,GO:0035771,"The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-4-mediated signaling pathway,biological_process
72123,GO:0035772,"The series of molecular signals initiated by interleukin-13 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-13-mediated signaling pathway,biological_process
72124,GO:0035773,"The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.",insulin secretion involved in cellular response to glucose stimulus,biological_process
72125,GO:0035774,"Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.",positive regulation of insulin secretion involved in cellular response to glucose stimulus,biological_process
72126,GO:0035775,The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.,pronephric glomerulus morphogenesis,biological_process
72127,GO:0035776,"The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.",pronephric proximal tubule development,biological_process
72128,GO:0035777,"The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.",pronephric distal tubule development,biological_process
72129,GO:0035778,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.,pronephric nephron tubule epithelial cell differentiation,biological_process
72130,GO:0035779,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).,angioblast cell differentiation,biological_process
72131,GO:0035782,The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.,mature natural killer cell chemotaxis,biological_process
72132,GO:0035783,"The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.","CD4-positive, alpha-beta T cell costimulation",biological_process
72133,GO:0035785,A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell.,intracellular nickel ion homeostasis,biological_process
72134,GO:0035787,"The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.",cell migration involved in kidney development,biological_process
72135,GO:0035788,"The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.",cell migration involved in metanephros development,biological_process
72136,GO:0035789,"The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.",metanephric mesenchymal cell migration,biological_process
72137,GO:0035790,"The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",platelet-derived growth factor receptor-alpha signaling pathway,biological_process
72138,GO:0035791,"The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",platelet-derived growth factor receptor-beta signaling pathway,biological_process
72139,GO:0035792,A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.,host cell postsynaptic membrane,cellular_component
72140,GO:0035793,"Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration resulting from the platelet-derived growth factor receptor-beta signaling pathway.",positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway,biological_process
72141,GO:0035794,"Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.",positive regulation of mitochondrial membrane permeability,biological_process
72142,GO:0035795,"Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.",negative regulation of mitochondrial membrane permeability,biological_process
72143,GO:0035796,"A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.","ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing",cellular_component
72144,GO:0035797,Catalysis of the reaction: tellurite + S-adenosyl-L-methionine = methanetellurite + S-adenosyl-L-homocysteine.,tellurite methyltransferase activity,molecular_function
72145,GO:0035798,Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.,2-alkenal reductase (NADPH) activity,molecular_function
72146,GO:0035799,"A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.",ureter maturation,biological_process
72147,GO:0035800,Binds to and increases the activity of a deubiquitinase.,deubiquitinase activator activity,molecular_function
72148,GO:0035801,"The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).",adrenal cortex development,biological_process
72149,GO:0035802,The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).,adrenal cortex formation,biological_process
72150,GO:0035803,"Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.",egg coat formation,biological_process
72151,GO:0035804,"The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.",structural constituent of egg coat,molecular_function
72152,GO:0035805,"A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.",egg coat,cellular_component
72153,GO:0035808,"A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins.",meiotic recombination initiation complex,cellular_component
72154,GO:0035809,Any process that modulates the amount of urine excreted from the body over a unit of time.,regulation of urine volume,biological_process
72155,GO:0035810,Any process that increases the amount of urine excreted from the body over a unit of time.,positive regulation of urine volume,biological_process
72156,GO:0035811,Any process that decreases the amount of urine excreted from the body over a unit of time.,negative regulation of urine volume,biological_process
72157,GO:0035812,The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.,renal sodium excretion,biological_process
72158,GO:0035813,Any process that modulates the amount of sodium excreted in urine over a unit of time.,regulation of renal sodium excretion,biological_process
72159,GO:0035814,Any process that decreases the amount of sodium excreted in urine over a unit of time.,negative regulation of renal sodium excretion,biological_process
72160,GO:0035815,Any process that increases the amount of sodium excreted in urine over a unit of time.,positive regulation of renal sodium excretion,biological_process
72161,GO:0035818,"An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.",positive regulation of urine volume by pressure natriuresis,biological_process
72162,GO:0035819,"An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.",positive regulation of renal sodium excretion by pressure natriuresis,biological_process
72163,GO:0035820,The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.,negative regulation of renal sodium excretion by angiotensin,biological_process
72164,GO:0035821,A process in which an organism effects a change in a biological process in another organism.,modulation of process of another organism,biological_process
72165,GO:0035822,A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor.,gene conversion,biological_process
72166,GO:0035823,A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor.,short tract gene conversion,biological_process
72167,GO:0035824,A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor.,long tract gene conversion,biological_process
72168,GO:0035825,A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules.,homologous recombination,biological_process
72169,GO:0035831,"The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.",palmatine biosynthetic process,biological_process
72170,GO:0035833,"The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.",berbamunine biosynthetic process,biological_process
72171,GO:0035834,"The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.",indole alkaloid metabolic process,biological_process
72172,GO:0035835,"The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.",indole alkaloid biosynthetic process,biological_process
72173,GO:0035837,The chemical reactions and pathways resulting in the formation of an ergot alkaloid.,ergot alkaloid biosynthetic process,biological_process
72174,GO:0035838,"The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.",growing cell tip,cellular_component
72175,GO:0035839,"A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.",non-growing cell tip,cellular_component
72176,GO:0035840,"A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.",old growing cell tip,cellular_component
72177,GO:0035841,"A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.",new growing cell tip,cellular_component
72178,GO:0035843,"A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope.",endonuclear canal,cellular_component
72179,GO:0035844,"The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.",cloaca development,biological_process
72180,GO:0035845,"A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.",photoreceptor cell outer segment organization,biological_process
72181,GO:0035846,"The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.",oviduct epithelium development,biological_process
72182,GO:0035847,The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.,uterine epithelium development,biological_process
72183,GO:0035848,"The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.",oviduct morphogenesis,biological_process
72184,GO:0035849,The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney.,nephric duct elongation,biological_process
72185,GO:0035850,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.,epithelial cell differentiation involved in kidney development,biological_process
72186,GO:0035851,"Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.",Krueppel-associated box domain binding,molecular_function
72187,GO:0035852,"Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.",horizontal cell localization,biological_process
72188,GO:0035853,"A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of th...",chromosome passenger complex localization to spindle midzone,biological_process
72189,GO:0035854,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.",eosinophil fate commitment,biological_process
72190,GO:0035855,"The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.",megakaryocyte development,biological_process
72191,GO:0035857,"The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.",eosinophil fate specification,biological_process
72192,GO:0035858,"The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.",eosinophil fate determination,biological_process
72193,GO:0035859,"A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.",Seh1-associated complex,cellular_component
72194,GO:0035860,The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.,glial cell-derived neurotrophic factor receptor signaling pathway,biological_process
72195,GO:0035861,A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.,site of double-strand break,cellular_component
72196,GO:0035863,"The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.",dITP catabolic process,biological_process
72197,GO:0035864,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.",response to potassium ion,biological_process
72198,GO:0035865,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.",cellular response to potassium ion,biological_process
72199,GO:0035866,A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.,alphav-beta3 integrin-PKCalpha complex,cellular_component
72200,GO:0035867,A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.,alphav-beta3 integrin-IGF-1-IGF1R complex,cellular_component
72201,GO:0035868,A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.,alphav-beta3 integrin-HMGB1 complex,cellular_component
72202,GO:0035869,A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.,ciliary transition zone,cellular_component
72203,GO:0035870,Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.,dITP diphosphatase activity,molecular_function
72204,GO:0035871,"A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.",protein K11-linked deubiquitination,biological_process
72205,GO:0035872,"The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number.","nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",biological_process
72206,GO:0035873,"The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.",lactate transmembrane transport,biological_process
72207,GO:0035874,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.",cellular response to copper ion starvation,biological_process
72208,GO:0035875,"The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.","maintenance of meiotic sister chromatid cohesion, centromeric",biological_process
72209,GO:0035877,"Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).",death effector domain binding,molecular_function
72210,GO:0035878,"The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.",nail development,biological_process
72211,GO:0035879,The directed movement of lactate across a plasma membrane.,plasma membrane lactate transport,biological_process
72212,GO:0035880,"The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.",embryonic nail plate morphogenesis,biological_process
72213,GO:0035881,"The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.",amacrine cell differentiation,biological_process
72214,GO:0035882,"The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.",defecation rhythm,biological_process
72215,GO:0035883,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.,enteroendocrine cell differentiation,biological_process
72216,GO:0035884,"The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.",arabinan biosynthetic process,biological_process
72217,GO:0035885,"Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.",exochitinase activity,molecular_function
72218,GO:0035886,The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.,vascular associated smooth muscle cell differentiation,biological_process
72219,GO:0035887,The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.,aortic smooth muscle cell differentiation,biological_process
72220,GO:0035888,Catalysis of the reaction: H+ + H2O + isoguanine = NH4+ + xanthine.,isoguanine deaminase activity,molecular_function
72221,GO:0035889,The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.,otolith tethering,biological_process
72222,GO:0035891,The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,exit from host cell,biological_process
72223,GO:0035898,The regulated release of parathyroid hormone into the circulatory system.,parathyroid hormone secretion,biological_process
72224,GO:0035900,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.",response to isolation stress,biological_process
72225,GO:0035902,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.",response to immobilization stress,biological_process
72226,GO:0035903,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.",cellular response to immobilization stress,biological_process
72227,GO:0035904,"The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.",aorta development,biological_process
72228,GO:0035905,"The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.",ascending aorta development,biological_process
72229,GO:0035906,"The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.",descending aorta development,biological_process
72230,GO:0035907,"The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.",dorsal aorta development,biological_process
72231,GO:0035908,"The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.",ventral aorta development,biological_process
72232,GO:0035909,The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.,aorta morphogenesis,biological_process
72233,GO:0035910,The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.,ascending aorta morphogenesis,biological_process
72234,GO:0035911,The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.,descending aorta morphogenesis,biological_process
72235,GO:0035912,The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.,dorsal aorta morphogenesis,biological_process
72236,GO:0035913,The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.,ventral aorta morphogenesis,biological_process
72237,GO:0035914,"The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.",skeletal muscle cell differentiation,biological_process
72238,GO:0035915,"The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism.",pore formation in membrane of another organism,biological_process
72239,GO:0035921,"The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.",desmosome disassembly,biological_process
72240,GO:0035922,"The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.",foramen ovale closure,biological_process
72241,GO:0035923,Binding to flurbiprofen.,flurbiprofen binding,molecular_function
72242,GO:0035924,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.",cellular response to vascular endothelial growth factor stimulus,biological_process
72243,GO:0035925,Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.,mRNA 3'-UTR AU-rich region binding,molecular_function
72244,GO:0035927,"The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix.",RNA import into mitochondrion,biological_process
72245,GO:0035928,"The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix.",rRNA import into mitochondrion,biological_process
72246,GO:0035929,The regulated release of any steroid that acts as a hormone into the circulatory system.,steroid hormone secretion,biological_process
72247,GO:0035930,The regulated release of any corticosteroid hormone into the circulatory system.,corticosteroid hormone secretion,biological_process
72248,GO:0035931,The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.,mineralocorticoid secretion,biological_process
72249,GO:0035932,"The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.",aldosterone secretion,biological_process
72250,GO:0035933,"The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.",glucocorticoid secretion,biological_process
72251,GO:0035934,The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.,corticosterone secretion,biological_process
72252,GO:0035935,The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.,androgen secretion,biological_process
72253,GO:0035936,"The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.",testosterone secretion,biological_process
72254,GO:0035937,The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.,estrogen secretion,biological_process
72255,GO:0035938,The regulated release of estradiol into the circulatory system.,estradiol secretion,biological_process
72256,GO:0035939,"Binding to a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem.",microsatellite binding,molecular_function
72257,GO:0035941,"The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.",androstenedione secretion,biological_process
72258,GO:0035942,The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.,dehydroepiandrosterone secretion,biological_process
72259,GO:0035943,The regulated release of estrone into the circulatory system.,estrone secretion,biological_process
72260,GO:0035944,"The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",perforin production,biological_process
72261,GO:0035945,The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.,mitochondrial ncRNA surveillance,biological_process
72262,GO:0035946,The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.,mitochondrial mRNA surveillance,biological_process
72263,GO:0035962,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.",response to interleukin-13,biological_process
72264,GO:0035963,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.",cellular response to interleukin-13,biological_process
72265,GO:0035964,"The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.",COPI-coated vesicle budding,biological_process
72266,GO:0035965,"Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.",cardiolipin acyl-chain remodeling,biological_process
72267,GO:0035966,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.",response to topologically incorrect protein,biological_process
72268,GO:0035967,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.",cellular response to topologically incorrect protein,biological_process
72269,GO:0035970,The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.,peptidyl-threonine dephosphorylation,biological_process
72270,GO:0035971,The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.,peptidyl-histidine dephosphorylation,biological_process
72271,GO:0035973,The selective degradation of protein aggregates by macroautophagy.,aggrephagy,biological_process
72272,GO:0035974,The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.,meiotic spindle pole body,cellular_component
72273,GO:0035976,"A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.",transcription factor AP-1 complex,cellular_component
72274,GO:0035977,The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.,protein deglycosylation involved in glycoprotein catabolic process,biological_process
72275,GO:0035979,Catalysis of the reaction: histone H2AX-serine (position 139) + ATP = histone H2AX-phosphoserine (position 139) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 139 of histone variant H2AX.,histone H2AXS139 kinase activity,molecular_function
72276,GO:0035981,The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.,tongue muscle cell differentiation,biological_process
72277,GO:0035983,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.",response to trichostatin A,biological_process
72278,GO:0035984,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.",cellular response to trichostatin A,biological_process
72279,GO:0035985,A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.,senescence-associated heterochromatin focus,cellular_component
72280,GO:0035987,"The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.",endodermal cell differentiation,biological_process
72281,GO:0035988,"The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.",chondrocyte proliferation,biological_process
72282,GO:0035989,"The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.",tendon development,biological_process
72283,GO:0035990,"The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.",tendon cell differentiation,biological_process
72284,GO:0035991,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO).",nitric oxide sensor activity,molecular_function
72285,GO:0035992,The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.,tendon formation,biological_process
72286,GO:0035993,"The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.",deltoid tuberosity development,biological_process
72287,GO:0035994,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.",response to muscle stretch,biological_process
72288,GO:0035995,The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.,detection of muscle stretch,biological_process
72289,GO:0035996,Thin cylindrical membrane-covered projection on the surface of a rhabdomere.,rhabdomere microvillus,cellular_component
72290,GO:0035997,The portion of the plasma membrane surrounding a microvillus of a rhabdomere.,rhabdomere microvillus membrane,cellular_component
72291,GO:0035999,"The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.",tetrahydrofolate interconversion,biological_process
72292,GO:0036000,"A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.",mucocyst,cellular_component
72293,GO:0036001,"The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.",'de novo' pyridoxal 5'-phosphate biosynthetic process,biological_process
72294,GO:0036002,"Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.",pre-mRNA binding,molecular_function
72295,GO:0036004,Binding to a GAF protein domain.,GAF domain binding,molecular_function
72296,GO:0036005,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.",response to macrophage colony-stimulating factor,biological_process
72297,GO:0036006,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.",cellular response to macrophage colony-stimulating factor stimulus,biological_process
72298,GO:0036007,"A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.",scintillon,cellular_component
72299,GO:0036009,Catalysis of the reaction: L-glutaminyl-[protein] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine + H+.,protein-glutamine N-methyltransferase activity,molecular_function
72300,GO:0036010,"A process in which a protein is transported to, or maintained in, a location within an endosome.",protein localization to endosome,biological_process
72301,GO:0036011,"Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.",imaginal disc-derived leg segmentation,biological_process
72302,GO:0036012,"The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma.",cyanelle inner membrane,cellular_component
72303,GO:0036013,"The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.",cyanelle outer membrane,cellular_component
72304,GO:0036014,The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer.,cyanelle intermembrane space,cellular_component
72305,GO:0036015,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.",response to interleukin-3,biological_process
72306,GO:0036016,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.",cellular response to interleukin-3,biological_process
72307,GO:0036017,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.",response to erythropoietin,biological_process
72308,GO:0036018,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.",cellular response to erythropoietin,biological_process
72309,GO:0036019,"An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.",endolysosome,cellular_component
72310,GO:0036020,The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.,endolysosome membrane,cellular_component
72311,GO:0036021,The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.,endolysosome lumen,cellular_component
72312,GO:0036022,The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.,limb joint morphogenesis,biological_process
72313,GO:0036023,"The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.",embryonic skeletal limb joint morphogenesis,biological_process
72314,GO:0036024,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.,protein C inhibitor-TMPRSS7 complex,cellular_component
72315,GO:0036025,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E.,protein C inhibitor-TMPRSS11E complex,cellular_component
72316,GO:0036026,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator.,protein C inhibitor-PLAT complex,cellular_component
72317,GO:0036027,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.,protein C inhibitor-PLAU complex,cellular_component
72318,GO:0036028,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin.,protein C inhibitor-thrombin complex,cellular_component
72319,GO:0036029,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen.,protein C inhibitor-KLK3 complex,cellular_component
72320,GO:0036030,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.,protein C inhibitor-plasma kallikrein complex,cellular_component
72321,GO:0036032,The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.,neural crest cell delamination,biological_process
72322,GO:0036033,"Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1...",mediator complex binding,molecular_function
72323,GO:0036034,"The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins...",mediator complex assembly,biological_process
72324,GO:0036035,The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.,osteoclast development,biological_process
72325,GO:0036036,The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.,cardiac neural crest cell delamination,biological_process
72326,GO:0036037,"The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.","CD8-positive, alpha-beta T cell activation",biological_process
72327,GO:0036038,"A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.",MKS complex,cellular_component
72328,GO:0036040,"The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.",curcumin catabolic process,biological_process
72329,GO:0036041,Binding to a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid binding,molecular_function
72330,GO:0036042,"Binding to a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty acyl-CoA binding,molecular_function
72331,GO:0036046,"The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.",protein demalonylation,biological_process
72332,GO:0036047,The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.,peptidyl-lysine demalonylation,biological_process
72333,GO:0036048,The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.,protein desuccinylation,biological_process
72334,GO:0036049,The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.,peptidyl-lysine desuccinylation,biological_process
72335,GO:0036051,"A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.",protein localization to trailing edge,biological_process
72336,GO:0036052,"A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell.",protein localization to uropod,biological_process
72337,GO:0036053,"A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.",glomerular endothelium fenestra,cellular_component
72338,GO:0036054,Catalysis of the reaction: N(6)-malonyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-malonyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].,protein-malonyllysine demalonylase activity,molecular_function
72339,GO:0036055,Catalysis of the reaction: N(6)-succinyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-succinyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].,protein-succinyllysine desuccinylase activity,molecular_function
72340,GO:0036056,"A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.",filtration diaphragm,cellular_component
72341,GO:0036057,"A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.",slit diaphragm,cellular_component
72342,GO:0036058,"The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.",filtration diaphragm assembly,biological_process
72343,GO:0036059,"The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.",nephrocyte diaphragm assembly,biological_process
72344,GO:0036060,"The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.",slit diaphragm assembly,biological_process
72345,GO:0036061,"The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.",muscle cell chemotaxis toward tendon cell,biological_process
72346,GO:0036062,"A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.",presynaptic periactive zone,cellular_component
72347,GO:0036063,"A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle.",acroblast,cellular_component
72348,GO:0036064,"A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar trans...",ciliary basal body,cellular_component
72349,GO:0036066,"A glycoprotein biosynthetic process starting with the covalent linkage of a fucose via an alpha-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. This modification typically occurs within specific motifs, such as EGF-like or thrombospondin type-1 repeats.",protein O-linked glycosylation via fucose,biological_process
72350,GO:0036067,"The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.",light-dependent chlorophyll biosynthetic process,biological_process
72351,GO:0036068,"The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.",light-independent chlorophyll biosynthetic process,biological_process
72352,GO:0036069,"The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.",light-dependent bacteriochlorophyll biosynthetic process,biological_process
72353,GO:0036070,"The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.",light-independent bacteriochlorophyll biosynthetic process,biological_process
72354,GO:0036072,"The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.",direct ossification,biological_process
72355,GO:0036073,"Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.",perichondral ossification,biological_process
72356,GO:0036074,Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.,metaplastic ossification,biological_process
72357,GO:0036075,Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.,replacement ossification,biological_process
72358,GO:0036076,Ossification wherein bone tissue forms within ligamentous tissue.,ligamentous ossification,biological_process
72359,GO:0036077,Ossification wherein bone tissue forms within tendonous tissue.,intratendonous ossification,biological_process
72360,GO:0036078,The removal of tubulin heterodimers from the minus end of a microtubule.,minus-end specific microtubule depolymerization,biological_process
72361,GO:0036080,Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.,purine nucleotide-sugar transmembrane transporter activity,molecular_function
72362,GO:0036081,Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH4+) has been bound by the channel complex or one of its constituent parts.,extracellular ammonia-gated monoatomic ion channel activity,molecular_function
72363,GO:0036082,Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.,extracellular phenylacetaldehyde-gated monoatomic ion channel activity,molecular_function
72364,GO:0036084,The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.,GDP-fucose import into endoplasmic reticulum lumen,biological_process
72365,GO:0036085,The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.,GDP-fucose import into Golgi lumen,biological_process
72366,GO:0036087,"A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer.",glutathione synthase complex,cellular_component
72367,GO:0036088,The chemical reactions and pathways resulting in the breakdown of D-serine.,D-serine catabolic process,biological_process
72368,GO:0036089,"Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.",cleavage furrow formation,biological_process
72369,GO:0036090,Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.,cleavage furrow ingression,biological_process
72370,GO:0036092,"The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.",phosphatidylinositol-3-phosphate biosynthetic process,biological_process
72371,GO:0036093,"The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.",germ cell proliferation,biological_process
72372,GO:0036094,"Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.",small molecule binding,molecular_function
72373,GO:0036098,The process by which an organism or tissue maintains a population of male germ-line stem cells.,male germ-line stem cell population maintenance,biological_process
72374,GO:0036099,The process by which an organism or tissue maintains a population of female germ-line stem cells.,female germ-line stem cell population maintenance,biological_process
72375,GO:0036100,"The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.",leukotriene catabolic process,biological_process
72376,GO:0036101,"The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.",leukotriene B4 catabolic process,biological_process
72377,GO:0036102,"The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.",leukotriene B4 metabolic process,biological_process
72378,GO:0036104,"The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.",Kdo2-lipid A biosynthetic process,biological_process
72379,GO:0036108,"The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).",4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process,biological_process
72380,GO:0036109,"The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.",alpha-linolenic acid metabolic process,biological_process
72381,GO:0036110,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.",cellular response to inositol starvation,biological_process
72382,GO:0036111,"The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.",very long-chain fatty-acyl-CoA metabolic process,biological_process
72383,GO:0036112,"The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.",medium-chain fatty-acyl-CoA metabolic process,biological_process
72384,GO:0036113,"The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.",very long-chain fatty-acyl-CoA catabolic process,biological_process
72385,GO:0036114,"The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.",medium-chain fatty-acyl-CoA catabolic process,biological_process
72386,GO:0036115,"The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.",fatty-acyl-CoA catabolic process,biological_process
72387,GO:0036116,"The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.",long-chain fatty-acyl-CoA catabolic process,biological_process
72388,GO:0036117,"A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.",hyaluranon cable,cellular_component
72389,GO:0036118,"A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.",hyaluranon cable assembly,biological_process
72390,GO:0036119,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.",response to platelet-derived growth factor,biological_process
72391,GO:0036120,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.",cellular response to platelet-derived growth factor stimulus,biological_process
72392,GO:0036121,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.",double-stranded DNA helicase activity,molecular_function
72393,GO:0036122,Binding to a member of the bone morphogenetic protein (BMP) family.,BMP binding,molecular_function
72394,GO:0036125,"A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).",fatty acid beta-oxidation multienzyme complex,cellular_component
72395,GO:0036126,"A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.",sperm flagellum,cellular_component
72396,GO:0036127,Binding to 3-sulfino-L-alanine (cysteine sulfinate).,3-sulfino-L-alanine binding,molecular_function
72397,GO:0036128,"A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.",CatSper complex,cellular_component
72398,GO:0036130,Catalysis of the reaction: prostaglandin F2alpha + NADP+ = prostaglandin H2 + NADPH + H+.,prostaglandin H2 endoperoxidase reductase activity,molecular_function
72399,GO:0036131,Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+.,prostaglandin D2 11-ketoreductase activity,molecular_function
72400,GO:0036133,Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.,11-hydroxythromboxane B2 dehydrogenase activity,molecular_function
72401,GO:0036134,Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).,12-hydroxyheptadecatrienoic acid synthase activity,molecular_function
72402,GO:0036135,The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function.,Schwann cell migration,biological_process
72403,GO:0036139,Catalysis of the reaction: L-histidyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + succinate + CO2.,peptidyl-histidine dioxygenase activity,molecular_function
72404,GO:0036140,Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.,[protein]-asparagine 3-dioxygenase activity,molecular_function
72405,GO:0036143,"Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.",kringle domain binding,molecular_function
72406,GO:0036145,The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,dendritic cell homeostasis,biological_process
72407,GO:0036146,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.",cellular response to mycotoxin,biological_process
72408,GO:0036147,"A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.",rumination,biological_process
72409,GO:0036148,"Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.",phosphatidylglycerol acyl-chain remodeling,biological_process
72410,GO:0036149,"Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.",phosphatidylinositol acyl-chain remodeling,biological_process
72411,GO:0036150,"Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.",phosphatidylserine acyl-chain remodeling,biological_process
72412,GO:0036151,"Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.",phosphatidylcholine acyl-chain remodeling,biological_process
72413,GO:0036152,"Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.",phosphatidylethanolamine acyl-chain remodeling,biological_process
72414,GO:0036153,"Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.",triglyceride acyl-chain remodeling,biological_process
72415,GO:0036154,"Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.",diacylglycerol acyl-chain remodeling,biological_process
72416,GO:0036155,"Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.",acylglycerol acyl-chain remodeling,biological_process
72417,GO:0036156,"Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.",inner dynein arm,cellular_component
72418,GO:0036157,"Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.",outer dynein arm,cellular_component
72419,GO:0036158,"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.",outer dynein arm assembly,biological_process
72420,GO:0036159,"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.",inner dynein arm assembly,biological_process
72421,GO:0036160,"The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.",melanocyte-stimulating hormone secretion,biological_process
72422,GO:0036161,"The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.",calcitonin secretion,biological_process
72423,GO:0036162,"The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.",oxytocin production,biological_process
72424,GO:0036164,The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.,cell-abiotic substrate adhesion,biological_process
72425,GO:0036165,The growth of colonies in filamentous chains of cells as a result of an increase in temperature.,invasive growth in response to heat,biological_process
72426,GO:0036166,"A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.",phenotypic switching,biological_process
72427,GO:0036168,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.",filamentous growth of a population of unicellular organisms in response to heat,biological_process
72428,GO:0036170,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.",filamentous growth of a population of unicellular organisms in response to starvation,biological_process
72429,GO:0036171,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.",filamentous growth of a population of unicellular organisms in response to chemical stimulus,biological_process
72430,GO:0036172,A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.,thiamine salvage,biological_process
72431,GO:0036173,"Binding to a thiosulfate, a sulfur oxide that has formula O3S2.",thiosulfate binding,molecular_function
72432,GO:0036174,Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.,butane monooxygenase activity,molecular_function
72433,GO:0036175,Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O = ribonucleoside diphosphate + glutaredoxin.,"ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor",molecular_function
72434,GO:0036176,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.",response to neutral pH,biological_process
72435,GO:0036177,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.",filamentous growth of a population of unicellular organisms in response to pH,biological_process
72436,GO:0036178,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.",filamentous growth of a population of unicellular organisms in response to neutral pH,biological_process
72437,GO:0036179,"A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.",osteoclast maturation,biological_process
72438,GO:0036180,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.",filamentous growth of a population of unicellular organisms in response to biotic stimulus,biological_process
72439,GO:0036181,"A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.",protein localization to linear element,biological_process
72440,GO:0036182,"The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.",asperthecin metabolic process,biological_process
72441,GO:0036183,"The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.",asperthecin catabolic process,biological_process
72442,GO:0036184,"The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.",asperthecin biosynthetic process,biological_process
72443,GO:0036185,"Catalysis of the reaction: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H+ = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD+.",13-lipoxin reductase activity,molecular_function
72444,GO:0036186,The lipid bilayer surrounding an early phagosome.,early phagosome membrane,cellular_component
72445,GO:0036187,The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.,"cell growth mode switching, budding to filamentous",biological_process
72446,GO:0036188,"Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.","abieta-7,13-dien-18-al (NAD+) dehydrogenase activity",molecular_function
72447,GO:0036189,"Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.","abieta-7,13-diene hydroxylase activity",molecular_function
72448,GO:0036190,Catalysis of the reaction: indole + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase].,indole-2-monooxygenase activity,molecular_function
72449,GO:0036191,Catalysis of the reaction: ndolin-2-one + reduced [NADPH-hemoprotein reductase] + O2 = 3-hydroxyindolin-2-one + oxidized [NADPH-hemoprotein reductase] + H2O + H+.,indolin-2-one monooxygenase activity,molecular_function
72450,GO:0036192,"Catalysis of the reaction: 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",3-hydroxyindolin-2-one monooxygenase activity,molecular_function
72451,GO:0036193,"Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase] = DIBOA + H+ + H2O + oxidized [NADPH--hemoprotein reductase].","2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity",molecular_function
72452,GO:0036194,"A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.",muscle cell projection,cellular_component
72453,GO:0036195,The portion of the plasma membrane surrounding a muscle cell projection.,muscle cell projection membrane,cellular_component
72454,GO:0036196,"The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).",zymosterol metabolic process,biological_process
72455,GO:0036197,"The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).",zymosterol biosynthetic process,biological_process
72456,GO:0036198,"Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.",dTMP salvage,biological_process
72457,GO:0036199,"Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.",cholest-4-en-3-one 26-monooxygenase activity,molecular_function
72458,GO:0036200,"Catalysis of the reaction: androsta-1,4-diene-3,17-dione + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].",3-ketosteroid 9-alpha-monooxygenase activity,molecular_function
72459,GO:0036201,Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.,ent-isokaurene C2-hydroxylase activity,molecular_function
72460,GO:0036202,"Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.","ent-cassa-12,15-diene 11-hydroxylase activity",molecular_function
72461,GO:0036203,"Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.",taxoid 14-beta-hydroxylase activity,molecular_function
72462,GO:0036204,"Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.","abieta-7,13-dien-18-ol hydroxylase activity",molecular_function
72463,GO:0036205,The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.,histone catabolic process,biological_process
72464,GO:0036209,"Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].","9beta-pimara-7,15-diene oxidase activity",molecular_function
72465,GO:0036211,"The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).",protein modification process,biological_process
72466,GO:0036213,The process of an actomyosin ring getting smaller in diameter.,contractile ring contraction,biological_process
72467,GO:0036215,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.",response to stem cell factor,biological_process
72468,GO:0036216,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.",cellular response to stem cell factor stimulus,biological_process
72469,GO:0036217,Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.,dGTP diphosphatase activity,molecular_function
72470,GO:0036218,Catalysis of the reaction: dTTP + H2O = dTMP + H+ + diphosphate.,dTTP diphosphatase activity,molecular_function
72471,GO:0036219,Catalysis of the reaction: GTP + H2O = GMP + H+ + diphosphate.,GTP diphosphatase activity,molecular_function
72472,GO:0036220,Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.,ITP diphosphatase activity,molecular_function
72473,GO:0036221,Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.,UTP diphosphatase activity,molecular_function
72474,GO:0036222,Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.,XTP diphosphatase activity,molecular_function
72475,GO:0036223,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.",cellular response to adenine starvation,biological_process
72476,GO:0036224,"A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.",pairing center,cellular_component
72477,GO:0036225,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).",cellular response to vitamin B1 starvation,biological_process
72478,GO:0036227,The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.,mitotic G2 cell cycle arrest in response to glucose starvation,biological_process
72479,GO:0036228,"A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane.",protein localization to nuclear inner membrane,biological_process
72480,GO:0036230,"The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",granulocyte activation,biological_process
72481,GO:0036237,Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.,acyl-glucuronidase activity,molecular_function
72482,GO:0036238,"Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.",gallate dioxygenase activity,molecular_function
72483,GO:0036239,"Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O. Also converts 2alpha-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin.",taxoid 7beta-hydroxylase activity,molecular_function
72484,GO:0036240,"The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.",septal periplasm,cellular_component
72485,GO:0036243,Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.,succinate-semialdehyde dehydrogenase (NADP+) activity,molecular_function
72486,GO:0036244,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.",cellular response to neutral pH,biological_process
72487,GO:0036245,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.",cellular response to menadione,biological_process
72488,GO:0036246,"The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.",phytochelatin 2 import into vacuole,biological_process
72489,GO:0036247,"The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.",phytochelatin 3 import into vacuole,biological_process
72490,GO:0036248,"The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.",phytochelatin 4 import into vacuole,biological_process
72491,GO:0036249,The directed movement of cadmium ions into the vacuole.,cadmium ion import into vacuole,biological_process
72492,GO:0036250,"The directed movement of a peroxisome along a microtubule, mediated by motor proteins.",peroxisome transport along microtubule,biological_process
72493,GO:0036255,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.",response to methylamine,biological_process
72494,GO:0036256,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.",cellular response to methylamine,biological_process
72495,GO:0036257,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.",multivesicular body organization,biological_process
72496,GO:0036258,"The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.",multivesicular body assembly,biological_process
72497,GO:0036259,The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.,aerobic raffinose catabolic process,biological_process
72498,GO:0036260,"The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts.",RNA capping,biological_process
72499,GO:0036261,"Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.",7-methylguanosine cap hypermethylation,biological_process
72500,GO:0036262,"The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",granulysin production,biological_process
72501,GO:0036265,The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.,RNA (guanine-N7)-methylation,biological_process
72502,GO:0036266,"A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p.",Cdc48p-Npl4p-Vms1p AAA ATPase complex,cellular_component
72503,GO:0036267,The growth of colonies in filamentous chains of cells into a substrate.,invasive filamentous growth,biological_process
72504,GO:0036268,"Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.",swimming,biological_process
72505,GO:0036269,The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.,swimming behavior,biological_process
72506,GO:0036270,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.",response to diuretic,biological_process
72507,GO:0036271,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.",response to methylphenidate,biological_process
72508,GO:0036272,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.",response to gemcitabine,biological_process
72509,GO:0036273,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.",response to statin,biological_process
72510,GO:0036274,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.",response to lapatinib,biological_process
72511,GO:0036275,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.",response to 5-fluorouracil,biological_process
72512,GO:0036276,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.",response to antidepressant,biological_process
72513,GO:0036277,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.",response to anticonvulsant,biological_process
72514,GO:0036279,"Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.",positive regulation of protein export from nucleus in response to glucose starvation,biological_process
72515,GO:0036280,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.",cellular response to L-canavanine,biological_process
72516,GO:0036284,Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.,tubulobulbar complex,cellular_component
72517,GO:0036285,"The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.",SAGA complex assembly,biological_process
72518,GO:0036286,"A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.",eisosome filament,cellular_component
72519,GO:0036287,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.",response to iloperidone,biological_process
72520,GO:0036288,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.",response to ximelagatran,biological_process
72521,GO:0036289,"The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.",peptidyl-serine autophosphorylation,biological_process
72522,GO:0036290,"The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.",protein trans-autophosphorylation,biological_process
72523,GO:0036293,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.",response to decreased oxygen levels,biological_process
72524,GO:0036294,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.",cellular response to decreased oxygen levels,biological_process
72525,GO:0036295,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.",cellular response to increased oxygen levels,biological_process
72526,GO:0036296,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.",response to increased oxygen levels,biological_process
72527,GO:0036297,"Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.",interstrand cross-link repair,biological_process
72528,GO:0036298,"Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.",recombinational interstrand cross-link repair,biological_process
72529,GO:0036299,Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.,non-recombinational interstrand cross-link repair,biological_process
72530,GO:0036300,A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.,B cell receptor internalization,biological_process
72531,GO:0036301,"The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",macrophage colony-stimulating factor production,biological_process
72532,GO:0036302,"The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.",atrioventricular canal development,biological_process
72533,GO:0036303,The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.,lymph vessel morphogenesis,biological_process
72534,GO:0036304,The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.,umbilical cord morphogenesis,biological_process
72535,GO:0036305,"The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.",ameloblast differentiation,biological_process
72536,GO:0036306,The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.,embryonic heart tube elongation,biological_process
72537,GO:0036307,Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.,23S rRNA (adenine(2030)-N(6))-methyltransferase activity,molecular_function
72538,GO:0036308,Catalysis of the reaction: guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine + H+.,16S rRNA (guanine(1516)-N(2))-methyltransferase activity,molecular_function
72539,GO:0036309,"Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.",protein localization to M-band,biological_process
72540,GO:0036310,An ATP-dependent activity that facilitates the formation of a complementary double-stranded DNA molecule.,ATP-dependent DNA/DNA annealing activity,molecular_function
72541,GO:0036311,"Catalysis of the reaction: H2O + N,N'-diacetylchitobiose = acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine.",chitin disaccharide deacetylase activity,molecular_function
72542,GO:0036312,Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.,phosphatidylinositol 3-kinase regulatory subunit binding,molecular_function
72543,GO:0036313,Binding to the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.,phosphatidylinositol 3-kinase catalytic subunit binding,molecular_function
72544,GO:0036314,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.",response to sterol,biological_process
72545,GO:0036315,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.",cellular response to sterol,biological_process
72546,GO:0036316,"Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which ...",SREBP-SCAP complex retention in endoplasmic reticulum,biological_process
72547,GO:0036317,"Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.",tyrosyl-RNA phosphodiesterase activity,molecular_function
72548,GO:0036318,"Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.",peptide pheromone receptor activity,molecular_function
72549,GO:0036319,"Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus.",mating-type M-factor pheromone receptor activity,molecular_function
72550,GO:0036320,"Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.",mating-type P-factor pheromone receptor activity,molecular_function
72551,GO:0036321,The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone.,ghrelin secretion,biological_process
72552,GO:0036322,The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.,pancreatic polypeptide secretion,biological_process
72553,GO:0036323,"The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-1 (VEGFR-1) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",vascular endothelial growth factor receptor-1 signaling pathway,biological_process
72554,GO:0036324,"The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",vascular endothelial growth factor receptor-2 signaling pathway,biological_process
72555,GO:0036325,"The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-3 (VEGFR-3) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",vascular endothelial growth factor receptor-3 signaling pathway,biological_process
72556,GO:0036331,"The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.",avascular cornea development in camera-type eye,biological_process
72557,GO:0036332,Combining with placental growth factor (PlGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.,placental growth factor receptor activity,molecular_function
72558,GO:0036333,Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.,hepatocyte homeostasis,biological_process
72559,GO:0036334,Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.,epidermal stem cell homeostasis,biological_process
72560,GO:0036335,Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.,intestinal stem cell homeostasis,biological_process
72561,GO:0036336,The movement of a dendritic cell within or between different tissues and organs of the body.,dendritic cell migration,biological_process
72562,GO:0036337,"The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.",Fas signaling pathway,biological_process
72563,GO:0036338,"The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.",viral membrane,cellular_component
72564,GO:0036339,"The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.",lymphocyte adhesion to endothelial cell of high endothelial venule,biological_process
72565,GO:0036340,"The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate.",chitin-based cuticle sclerotization by biomineralization,biological_process
72566,GO:0036341,"The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.",chitin-based cuticle sclerotization by protein cross-linking,biological_process
72567,GO:0036342,The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.,post-anal tail morphogenesis,biological_process
72568,GO:0036343,"The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.",psychomotor behavior,biological_process
72569,GO:0036344,"Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.",platelet morphogenesis,biological_process
72570,GO:0036345,"A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.",platelet maturation,biological_process
72571,GO:0036346,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.",cellular response to L-cysteine,biological_process
72572,GO:0036348,Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.,hydantoin racemase activity,molecular_function
72573,GO:0036349,The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.,galactose-specific flocculation,biological_process
72574,GO:0036350,The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.,mannose-specific flocculation,biological_process
72575,GO:0036354,Catalysis of the reaction: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD+ = bacteriochlorophyllide a + NADH + H+.,bacteriochlorophyllide-a dehydrogenase activity,molecular_function
72576,GO:0036355,Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.,2-iminoacetate synthase activity,molecular_function
72577,GO:0036356,"Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate.","cyclic 2,3-diphosphoglycerate synthetase activity",molecular_function
72578,GO:0036358,The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).,lipoteichoic acid D-alanylation,biological_process
72579,GO:0036359,The elimination of potassium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.,renal potassium excretion,biological_process
72580,GO:0036360,The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.,sorocarp stalk morphogenesis,biological_process
72581,GO:0036362,"A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.",ascus membrane,cellular_component
72582,GO:0036367,The ability of a photoreceptor to adjust to varying levels of light.,light adaption,biological_process
72583,GO:0036368,"The processes required for a photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Photoreceptor recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.",photoresponse recovery,biological_process
72584,GO:0036370,Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG).,D-alanyl carrier activity,molecular_function
72585,GO:0036371,"A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.",protein localization to T-tubule,biological_process
72586,GO:0036372,"The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.",opsin transport,biological_process
72587,GO:0036373,Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.,L-fucose mutarotase activity,molecular_function
72588,GO:0036374,Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.,glutathione gamma-glutamate hydrolase,molecular_function
72589,GO:0036375,"An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.",Kibra-Ex-Mer complex,cellular_component
72590,GO:0036376,"The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.",sodium ion export across plasma membrane,biological_process
72591,GO:0036377,"A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.",arbuscular mycorrhizal association,biological_process
72592,GO:0036379,Any of the smallest contractile units of a myofibril (striated muscle fiber).,myofilament,cellular_component
72593,GO:0036380,"Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.",UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity,molecular_function
72594,GO:0036381,"Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH4+, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH4+ = pyridoxal 5'-phosphate + 4 H2O + phosphate.",pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity,molecular_function
72595,GO:0036382,Catalysis of the reaction: a reduced flavin + NAD+ = an oxidized flavin + 2 H+ + NADH.,flavin reductase (NADH) activity,molecular_function
72596,GO:0036383,"Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.","3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity",molecular_function
72597,GO:0036384,Catalysis of the reaction: CDP + H2O = CMP + phosphate.,CDP phosphatase activity,molecular_function
72598,GO:0036386,"A process in which chromosomal DNA and associated proteins organize into a compact, orderly bacterial nucleoid. Often resulting in DNA supercoiling.",bacterial nucleoid DNA packaging,biological_process
72599,GO:0036387,"A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.",pre-replicative complex,cellular_component
72600,GO:0036388,"The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.",pre-replicative complex assembly,biological_process
72601,GO:0036389,"A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.",bacterial pre-replicative complex,cellular_component
72602,GO:0036391,A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.,medial cortex septin ring,cellular_component
72603,GO:0036392,"The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 20 production,biological_process
72604,GO:0036393,Catalysis of the reaction: thiocyanate + H2O2 + H+ = hypothiocyanous acid + H2O.,thiocyanate peroxidase activity,molecular_function
72605,GO:0036394,The controlled release of amylase from a cell.,amylase secretion,biological_process
72606,GO:0036395,The controlled release of amylase from a cell of the pancreas.,pancreatic amylase secretion,biological_process
72607,GO:0036396,"A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).",RNA N6-methyladenosine methyltransferase complex,cellular_component
72608,GO:0036397,Catalysis of the reaction: formate + a quinone = CO2 + a quinol.,formate dehydrogenase (quinone) activity,molecular_function
72609,GO:0036398,"A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.",TCR signalosome,cellular_component
72610,GO:0036399,"The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.",TCR signalosome assembly,biological_process
72611,GO:0036400,Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide.,short neuropeptide F receptor activity,molecular_function
72612,GO:0036401,"Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.",pyrokinin receptor activity,molecular_function
72613,GO:0036402,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.",proteasome-activating activity,molecular_function
72614,GO:0036403,"Catalysis of the reaction: arachidonate + O2 = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.",arachidonate 8(S)-lipoxygenase activity,molecular_function
72615,GO:0036407,A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria).,mycolate outer membrane,cellular_component
72616,GO:0036408,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).,histone H3K14 acetyltransferase activity,molecular_function
72617,GO:0036409,A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.,histone H3-K14 acetyltransferase complex,cellular_component
72618,GO:0036410,"A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.",Mst2 histone acetyltransferase complex,cellular_component
72619,GO:0036411,"A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.",H-NS-Cnu complex,cellular_component
72620,GO:0036412,Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.,acetyl-CoA:oxalate CoA-transferase activity,molecular_function
72621,GO:0036415,Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.,regulation of tRNA stability,biological_process
72622,GO:0036416,Prevention of degradation of tRNA molecules.,tRNA stabilization,biological_process
72623,GO:0036417,"Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.",tRNA destabilization,biological_process
72624,GO:0036420,"The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of mycolate outer membrane,cellular_component
72625,GO:0036421,"The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.",extrinsic component of external side of mycolate outer membrane,cellular_component
72626,GO:0036423,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.","hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity",molecular_function
72627,GO:0036424,"Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid.",L-phosphoserine phosphatase activity,molecular_function
72628,GO:0036427,Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.,all-trans-undecaprenyl-phosphate mannosyltransferase activity,molecular_function
72629,GO:0036430,Catalysis of the reaction: ATP + CMP = ADP + CDP.,CMP kinase activity,molecular_function
72630,GO:0036431,Catalysis of the reaction: ATP + dCMP = ADP + dCDP.,dCMP kinase activity,molecular_function
72631,GO:0036432,Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.,all-trans undecaprenol kinase activity,molecular_function
72632,GO:0036433,"Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.","di-trans, poly-cis-undecaprenol kinase activity",molecular_function
72633,GO:0036434,Catalysis of the reaction: ethylnitronate + FMNH(2) + O2 = acetaldehyde + FMN + H2O + H+ + nitrite.,nitronate monooxygenase (FMN-linked) activity,molecular_function
72634,GO:0036435,Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.,K48-linked polyubiquitin modification-dependent protein binding,molecular_function
72635,GO:0036436,"An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.",Isw1a complex,cellular_component
72636,GO:0036437,"An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.",Isw1b complex,cellular_component
72637,GO:0036438,"A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina.",maintenance of lens transparency,biological_process
72638,GO:0036440,Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.,citrate synthase activity,molecular_function
72639,GO:0036441,Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.,2-dehydropantolactone reductase activity,molecular_function
72640,GO:0036444,A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix.,calcium import into the mitochondrion,biological_process
72641,GO:0036445,The self-renewing division of a neuronal stem cell.,neuronal stem cell division,biological_process
72642,GO:0036446,The process in which an undifferentiated cell acquires the features of a myofibroblast cell.,myofibroblast differentiation,biological_process
72643,GO:0036447,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.",cellular response to sugar-phosphate stress,biological_process
72644,GO:0036448,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.",cellular response to glucose-phosphate stress,biological_process
72645,GO:0036449,The end of a microtubule that does not preferentially grow (polymerize).,microtubule minus-end,cellular_component
72646,GO:0036450,Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.,polyuridylation-dependent decapping of nuclear-transcribed mRNA,biological_process
72647,GO:0036452,"An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.",ESCRT complex,cellular_component
72648,GO:0036453,"An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.",transitive RNA interference,biological_process
72649,GO:0036454,A protein complex that has growth factor activity.,growth factor complex,cellular_component
72650,GO:0036455,Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).,iron-sulfur transferase activity,molecular_function
72651,GO:0036457,"A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.",keratohyalin granule,cellular_component
72652,GO:0036458,Binding to a hepatocyte growth factor.,hepatocyte growth factor binding,molecular_function
72653,GO:0036460,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.",cellular response to cell envelope stress,biological_process
72654,GO:0036461,"Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.",BLOC-2 complex binding,molecular_function
72655,GO:0036462,An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.,TRAIL-activated apoptotic signaling pathway,biological_process
72656,GO:0036463,Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.,TRAIL receptor activity,molecular_function
72657,GO:0036464,A ribonucleoprotein granule located in the cytoplasm.,cytoplasmic ribonucleoprotein granule,cellular_component
72658,GO:0036465,"The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic me...",synaptic vesicle recycling,biological_process
72659,GO:0036466,Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate.,synaptic vesicle recycling via endosome,biological_process
72660,GO:0036467,Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.,5-hydroxy-L-tryptophan decarboxylase activity,molecular_function
72661,GO:0036468,Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.,L-dopa decarboxylase activity,molecular_function
72662,GO:0036469,Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.,L-tryptophan decarboxylase activity,molecular_function
72663,GO:0036470,Binds to and increases the activity of tyrosine 3-monooxygenase (tyrosine hydroxylase).,tyrosine 3-monooxygenase activator activity,molecular_function
72664,GO:0036471,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.",cellular response to glyoxal,biological_process
72665,GO:0036477,"The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.",somatodendritic compartment,cellular_component
72666,GO:0036478,Interacts with and increases L-dopa decarboxylase activity.,L-dopa decarboxylase activator activity,molecular_function
72667,GO:0036479,"Binds to and stops, prevents or reduces the activity of peroxidase.",peroxidase inhibitor activity,molecular_function
72668,GO:0036480,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.",neuron intrinsic apoptotic signaling pathway in response to oxidative stress,biological_process
72669,GO:0036481,The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).,intrinsic apoptotic signaling pathway in response to hydrogen peroxide,biological_process
72670,GO:0036482,The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide.,neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide,biological_process
72671,GO:0036483,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.",neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,biological_process
72672,GO:0036484,The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.,trunk neural crest cell migration,biological_process
72673,GO:0036485,"The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells.",dorsolateral trunk neural crest cell migration,biological_process
72674,GO:0036486,"The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta.",ventral trunk neural crest cell migration,biological_process
72675,GO:0036487,"Binds to and stops, prevents or reduces the activity of nitric oxide synthase.",nitric-oxide synthase inhibitor activity,molecular_function
72676,GO:0036488,A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.,CHOP-C/EBP complex,cellular_component
72677,GO:0036489,"The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers.",neuromelanin biosynthetic process,biological_process
72678,GO:0036490,"Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.",regulation of translation in response to endoplasmic reticulum stress,biological_process
72679,GO:0036491,"Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress.",regulation of translation initiation in response to endoplasmic reticulum stress,biological_process
72680,GO:0036492,"The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.",eiF2alpha phosphorylation in response to endoplasmic reticulum stress,biological_process
72681,GO:0036493,"Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.",positive regulation of translation in response to endoplasmic reticulum stress,biological_process
72682,GO:0036494,"Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.",positive regulation of translation initiation in response to endoplasmic reticulum stress,biological_process
72683,GO:0036495,"Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.",negative regulation of translation initiation in response to endoplasmic reticulum stress,biological_process
72684,GO:0036496,"Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.",regulation of translational initiation by eIF2 alpha dephosphorylation,biological_process
72685,GO:0036497,"The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.",eIF2alpha dephosphorylation in response to endoplasmic reticulum stress,biological_process
72686,GO:0036498,"The series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcripti...",IRE1-mediated unfolded protein response,biological_process
72687,GO:0036499,"The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylat...",PERK-mediated unfolded protein response,biological_process
72688,GO:0036500,"The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator...",ATF6-mediated unfolded protein response,biological_process
72689,GO:0036501,"A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p.",UFD1-NPL4 complex,cellular_component
72690,GO:0036502,"A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.",Derlin-1-VIMP complex,cellular_component
72691,GO:0036503,"The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.",ERAD pathway,biological_process
72692,GO:0036504,The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.,Golgi membrane fusion,biological_process
72693,GO:0036505,"Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D).",prosaposin receptor activity,molecular_function
72694,GO:0036507,The removal of one or more mannose residues from a mannosylated protein.,protein demannosylation,biological_process
72695,GO:0036508,"The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.","protein alpha-1,2-demannosylation",biological_process
72696,GO:0036510,"The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.",trimming of terminal mannose on C branch,biological_process
72697,GO:0036513,"A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.",Derlin-1 retrotranslocation complex,cellular_component
72698,GO:0036514,The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.,dopaminergic neuron axon guidance,biological_process
72699,GO:0036515,The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.,serotonergic neuron axon guidance,biological_process
72700,GO:0036516,The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.,chemoattraction of dopaminergic neuron axon,biological_process
72701,GO:0036517,The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.,chemoattraction of serotonergic neuron axon,biological_process
72702,GO:0036518,The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.,chemorepulsion of dopaminergic neuron axon,biological_process
72703,GO:0036519,The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.,chemorepulsion of serotonergic neuron axon,biological_process
72704,GO:0036520,Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.,astrocyte-dopaminergic neuron signaling,biological_process
72705,GO:0036522,A process in which a symbiont inhibits or disrupts the normal localization of a protein to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host protein localization to phagocytic vesicle,biological_process
72706,GO:0036524,"Catalysis of the removal of a sugar or dicarbonyl from a glycated L-arginine, L-lysine or L-cysteine residue within proteins that have been attacked and modified by glyoxal or 2-oxopropanal.",protein deglycase activity,molecular_function
72707,GO:0036525,The removal of a sugar or dicarbonyl from a glycated protein.,protein deglycation,biological_process
72708,GO:0036528,The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.,peptidyl-lysine deglycation,biological_process
72709,GO:0036529,"The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.","protein deglycation, glyoxal removal",biological_process
72710,GO:0036530,"The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.","protein deglycation, methylglyoxal removal",biological_process
72711,GO:0038001,"The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.",paracrine signaling,biological_process
72712,GO:0038002,"The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.",endocrine signaling,biological_process
72713,GO:0038003,"A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",G protein-coupled opioid receptor signaling pathway,biological_process
72714,GO:0038004,Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.,epidermal growth factor receptor ligand maturation,biological_process
72715,GO:0038006,Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.,netrin receptor activity involved in chemoattraction,molecular_function
72716,GO:0038007,"The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.",netrin-activated signaling pathway,biological_process
72717,GO:0038009,"Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.",regulation of signal transduction by receptor internalization,biological_process
72718,GO:0038010,"Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.",positive regulation of signal transduction by receptor internalization,biological_process
72719,GO:0038011,"Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.",negative regulation of signal transduction by receptor internalization,biological_process
72720,GO:0038014,"Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.",negative regulation of insulin receptor signaling pathway by insulin receptor internalization,biological_process
72721,GO:0038015,"Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.",positive regulation of insulin receptor signaling pathway by insulin receptor internalization,biological_process
72722,GO:0038016,A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.,insulin receptor internalization,biological_process
72723,GO:0038017,A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell.,Wnt receptor internalization,biological_process
72724,GO:0038018,The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.,Wnt receptor catabolic process,biological_process
72725,GO:0038019,The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.,Wnt receptor recycling,biological_process
72726,GO:0038020,The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.,insulin receptor recycling,biological_process
72727,GO:0038021,Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,leptin receptor activity,molecular_function
72728,GO:0038022,Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled olfactory receptor activity,molecular_function
72729,GO:0038023,Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.,signaling receptor activity,molecular_function
72730,GO:0038024,"Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span membranes (for instance the plasma membrane or the endoplasmic reticulum membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit the cargo molecules to nascent vesicles.",cargo receptor activity,molecular_function
72731,GO:0038025,"Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",reelin receptor activity,molecular_function
72732,GO:0038026,"The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",reelin-mediated signaling pathway,biological_process
72733,GO:0038027,"The series of molecular signals initiated by apolipoprotein A-I binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",apolipoprotein A-I-mediated signaling pathway,biological_process
72734,GO:0038032,"The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.",termination of G protein-coupled receptor signaling pathway,biological_process
72735,GO:0038033,"The series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.",positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway,biological_process
72736,GO:0038034,The series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.,signal transduction in absence of ligand,biological_process
72737,GO:0038035,"A G protein-coupled receptor signaling pathway in which the receptor constitutively activates adenylate cyclase, without binding to an agonist.",ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway,biological_process
72738,GO:0038036,"Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.",sphingosine-1-phosphate receptor activity,molecular_function
72739,GO:0038037,A protein complex that contains two G protein-coupled receptors.,G protein-coupled receptor dimeric complex,cellular_component
72740,GO:0038038,"A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.",G protein-coupled receptor homodimeric complex,cellular_component
72741,GO:0038039,A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR.,G protein-coupled receptor heterodimeric complex,cellular_component
72742,GO:0038041,"Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.",cross-receptor inhibition within G protein-coupled receptor heterodimer,biological_process
72743,GO:0038043,"The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-5-mediated signaling pathway,biological_process
72744,GO:0038045,"A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors.",large latent transforming growth factor-beta complex,cellular_component
72745,GO:0038046,"Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body.",G protein-coupled enkephalin receptor activity,molecular_function
72746,GO:0038047,"Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein.",morphine receptor activity,molecular_function
72747,GO:0038048,"Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.",dynorphin receptor activity,molecular_function
72748,GO:0038054,Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled estrogen receptor activity,molecular_function
72749,GO:0038055,The controlled release of a member of the BMP family of proteins from a cell.,BMP secretion,biological_process
72750,GO:0038057,"Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.",TNFSF11 binding,molecular_function
72751,GO:0038059,A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.,IKKalpha-IKKalpha complex,cellular_component
72752,GO:0038060,"An intracellular signaling cassette in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.",nitric oxide-cGMP-mediated signaling,biological_process
72753,GO:0038061,"An intracellular signaling cassette characterized by the NIK-dependent processing and activation of NF-kappaB. Begins with activation of the NF-kappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-kappa B2 protein (p100) leading to p100 processing and release of an active NF-kappaB (p52). The non-canonical NF-kappaB signaling pathway is generally activated by ligands of the TNF receptor superfamily, including ...",non-canonical NF-kappaB signal transduction,biological_process
72754,GO:0038062,Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.,protein tyrosine kinase collagen receptor activity,molecular_function
72755,GO:0038063,"The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.",collagen-activated tyrosine kinase receptor signaling pathway,biological_process
72756,GO:0038064,Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,collagen receptor activity,molecular_function
72757,GO:0038065,"The series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",collagen-activated signaling pathway,biological_process
72758,GO:0038066,"A MAPK cascade containing at least the p38MAPK (MAPK14) MAP kinase, or Hog1 in yeast. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of p38MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The p38MAPK cascade is activated by stress signals, including hyperosmolarity, as well as by G protein-coupled receptors, growth factors, and cytokines, a...",p38MAPK cascade,biological_process
72759,GO:0038083,"The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.",peptidyl-tyrosine autophosphorylation,biological_process
72760,GO:0038084,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",vascular endothelial growth factor signaling pathway,biological_process
72761,GO:0038085,Binding to a vascular endothelial growth factor.,vascular endothelial growth factor binding,molecular_function
72762,GO:0038086,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",VEGF-activated platelet-derived growth factor receptor signaling pathway,biological_process
72763,GO:0038087,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway,biological_process
72764,GO:0038088,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",VEGF-activated platelet-derived growth factor receptor-beta signaling pathway,biological_process
72765,GO:0038089,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.",positive regulation of cell migration by vascular endothelial growth factor signaling pathway,biological_process
72766,GO:0038090,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.",positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway,biological_process
72767,GO:0038091,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.",positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway,biological_process
72768,GO:0038092,"The series of molecular signals initiated by nodal protein binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",nodal signaling pathway,biological_process
72769,GO:0038093,"The series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.",Fc receptor signaling pathway,biological_process
72770,GO:0038094,"The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.",Fc-gamma receptor signaling pathway,biological_process
72771,GO:0038095,"The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.",Fc-epsilon receptor signaling pathway,biological_process
72772,GO:0038096,An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.,Fc-gamma receptor signaling pathway involved in phagocytosis,biological_process
72773,GO:0038097,"An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.",positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway,biological_process
72774,GO:0038099,"The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals).",nodal receptor complex assembly,biological_process
72775,GO:0038100,"Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.",nodal binding,molecular_function
72776,GO:0038102,"Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.",activin receptor antagonist activity,molecular_function
72777,GO:0038104,"A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.",nodal receptor complex,cellular_component
72778,GO:0038106,"Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.",choriogonadotropin hormone binding,molecular_function
72779,GO:0038108,"The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.",negative regulation of appetite by leptin-mediated signaling pathway,biological_process
72780,GO:0038109,"The series of molecular signals initiated by the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling c...",Kit signaling pathway,biological_process
72781,GO:0038110,"The series of molecular signals initiated by interleukin-2 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-2-mediated signaling pathway,biological_process
72782,GO:0038111,"The series of molecular signals initiated by interleukin-7 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-7-mediated signaling pathway,biological_process
72783,GO:0038112,"The series of molecular signals initiated by interleukin-8 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-8-mediated signaling pathway,biological_process
72784,GO:0038113,"The series of molecular signals initiated by interleukin-9 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-9-mediated signaling pathway,biological_process
72785,GO:0038114,"The series of molecular signals initiated by interleukin-21 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-21-mediated signaling pathway,biological_process
72786,GO:0038115,"The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine (C-C motif) ligand 19 signaling pathway,biological_process
72787,GO:0038116,"The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine (C-C motif) ligand 21 signaling pathway,biological_process
72788,GO:0038117,Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,C-C motif chemokine 19 receptor activity,molecular_function
72789,GO:0038118,"The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.",C-C chemokine receptor CCR7 signaling pathway,biological_process
72790,GO:0038119,"The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",CCL19-activated CCR7 signaling pathway,biological_process
72791,GO:0038120,"The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",CCL21-activated CCR7 signaling pathway,biological_process
72792,GO:0038121,Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,C-C motif chemokine 21 receptor activity,molecular_function
72793,GO:0038122,Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,C-C motif chemokine 5 receptor activity,molecular_function
72794,GO:0038123,"The series of molecular signals initiated by a ligand binding of a heterodimeric TLR1:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",toll-like receptor TLR1:TLR2 signaling pathway,biological_process
72795,GO:0038124,"The series of molecular signals initiated by a ligand binding of a heterodimeric TLR6:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",toll-like receptor TLR6:TLR2 signaling pathway,biological_process
72796,GO:0038127,"The series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",ERBB signaling pathway,biological_process
72797,GO:0038128,"The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.",ERBB2 signaling pathway,biological_process
72798,GO:0038129,"The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.",ERBB3 signaling pathway,biological_process
72799,GO:0038130,"The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",ERBB4 signaling pathway,biological_process
72800,GO:0038131,"Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.",neuregulin receptor activity,molecular_function
72801,GO:0038132,"Binding to a neuregulin, a member of the EGF family of growth factors.",neuregulin binding,molecular_function
72802,GO:0038133,"The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.",ERBB2-ERBB3 signaling pathway,biological_process
72803,GO:0038134,"The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.",ERBB2-EGFR signaling pathway,biological_process
72804,GO:0038135,"The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.",ERBB2-ERBB4 signaling pathway,biological_process
72805,GO:0038136,"The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.",ERBB3-ERBB4 signaling pathway,biological_process
72806,GO:0038137,"The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.",ERBB4-EGFR signaling pathway,biological_process
72807,GO:0038138,"The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.",ERBB4-ERBB4 signaling pathway,biological_process
72808,GO:0038139,A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1).,ERBB4-EGFR complex,cellular_component
72809,GO:0038140,A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.,ERBB4-ERBB3 complex,cellular_component
72810,GO:0038141,A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).,ERBB4-ERBB4 complex,cellular_component
72811,GO:0038142,"A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.",EGFR:ERBB2 complex,cellular_component
72812,GO:0038143,"A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.",ERBB3:ERBB2 complex,cellular_component
72813,GO:0038144,"A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.",ERBB4:ERBB2 complex,cellular_component
72814,GO:0038145,"The series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",macrophage colony-stimulating factor signaling pathway,biological_process
72815,GO:0038146,"The series of molecular signals initiated by the binding of the chemokine CXCL12 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine (C-X-C motif) ligand 12 signaling pathway,biological_process
72816,GO:0038147,Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,C-X-C motif chemokine 12 receptor activity,molecular_function
72817,GO:0038148,"The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine (C-C motif) ligand 2 signaling pathway,biological_process
72818,GO:0038149,Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,C-C motif chemokine 2 receptor activity,molecular_function
72819,GO:0038150,"The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.",C-C chemokine receptor CCR2 signaling pathway,biological_process
72820,GO:0038151,"The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",CCL2-activated CCR2 signaling pathway,biological_process
72821,GO:0038152,"The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.",C-C chemokine receptor CCR4 signaling pathway,biological_process
72822,GO:0038153,"The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",CCL2-activated CCR4 signaling pathway,biological_process
72823,GO:0038154,"The series of molecular signals initiated by the binding of interleukin-11 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-11-mediated signaling pathway,biological_process
72824,GO:0038155,"The series of molecular signals initiated by interleukin-23 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-23-mediated signaling pathway,biological_process
72825,GO:0038156,"The series of molecular signals initiated by interleukin-3 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-3-mediated signaling pathway,biological_process
72826,GO:0038157,"The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.",granulocyte-macrophage colony-stimulating factor signaling pathway,biological_process
72827,GO:0038158,"The series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).",granulocyte colony-stimulating factor signaling pathway,biological_process
72828,GO:0038159,"The series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.",C-X-C chemokine receptor CXCR4 signaling pathway,biological_process
72829,GO:0038160,"The series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",CXCL12-activated CXCR4 signaling pathway,biological_process
72830,GO:0038161,"The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",prolactin signaling pathway,biological_process
72831,GO:0038162,"The series of molecular signals initiated by erythropoietin (EPO) binding to the erythropoietin receptor (EPO-R) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",erythropoietin-mediated signaling pathway,biological_process
72832,GO:0038163,"The series of molecular signals initiated by thrombopoietin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",thrombopoietin-mediated signaling pathway,biological_process
72833,GO:0038164,Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,thrombopoietin receptor activity,molecular_function
72834,GO:0038165,"The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.",oncostatin-M-mediated signaling pathway,biological_process
72835,GO:0038166,"A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",angiotensin-activated signaling pathway,biological_process
72836,GO:0038169,"A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.",somatostatin receptor signaling pathway,biological_process
72837,GO:0038170,"A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription.",somatostatin signaling pathway,biological_process
72838,GO:0038171,"A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.",cannabinoid signaling pathway,biological_process
72839,GO:0038172,"The series of molecular signals initiated by interleukin-33 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-33-mediated signaling pathway,biological_process
72840,GO:0038173,"The series of molecular signals initiated by interleukin-17A binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-17A-mediated signaling pathway,biological_process
72841,GO:0038174,Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-17A receptor activity,molecular_function
72842,GO:0038175,"Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.",negative regulation of SREBP signaling pathway in response to increased oxygen levels,biological_process
72843,GO:0038176,"Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.",positive regulation of SREBP signaling pathway in response to decreased oxygen levels,biological_process
72844,GO:0038177,Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.,death receptor agonist activity,molecular_function
72845,GO:0038178,"A G protein-coupled receptor signaling pathway initiated by a C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.",complement component C5a signaling pathway,biological_process
72846,GO:0038179,"The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.",neurotrophin signaling pathway,biological_process
72847,GO:0038180,"The series of molecular signals initiated by nerve growth factor (NGF) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",nerve growth factor signaling pathway,biological_process
72848,GO:0038182,Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled bile acid receptor activity,molecular_function
72849,GO:0038183,"The series of molecular signals initiated by bile acid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",bile acid signaling pathway,biological_process
72850,GO:0038184,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to a bile acid receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway,biological_process
72851,GO:0038185,"A nuclear receptor-mediated signaling pathway initiated by a bile acid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated bile acid signaling pathway,biological_process
72852,GO:0038186,A nuclear receptor activity regulated by a bile acid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II.,bile acid nuclear receptor activity,molecular_function
72853,GO:0038187,"Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.",pattern recognition receptor activity,molecular_function
72854,GO:0038188,"A G protein-coupled receptor signaling pathway initiated by cholecystokinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",cholecystokinin signaling pathway,biological_process
72855,GO:0038189,"The series of molecular signals initiated by an extracellular ligand binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",neuropilin signaling pathway,biological_process
72856,GO:0038190,"The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",VEGF-activated neuropilin signaling pathway,biological_process
72857,GO:0038191,Binding to a member of the neuropilin family.,neuropilin binding,molecular_function
72858,GO:0038192,"A G protein-coupled receptor signaling pathway initiated by gastric inhibitory peptide (GIP) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",gastric inhibitory peptide signaling pathway,biological_process
72859,GO:0038193,"A G protein-coupled receptor signaling pathway initiated by thromboxane A2 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",thromboxane A2 signaling pathway,biological_process
72860,GO:0038194,"A G protein-coupled receptor signaling pathway initiated by thyroid-stimulating hormone (thyrotropin) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",thyroid-stimulating hormone signaling pathway,biological_process
72861,GO:0038195,"The series of molecular signals initiated by urokinase plasminogen activator binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",urokinase plasminogen activator signaling pathway,biological_process
72862,GO:0038196,"The series of molecular signals initiated by type III interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far.",type III interferon-mediated signaling pathway,biological_process
72863,GO:0038197,A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).,type I interferon receptor complex,cellular_component
72864,GO:0038198,Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).,auxin receptor activity,molecular_function
72865,GO:0038199,Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.,ethylene receptor activity,molecular_function
72866,GO:0038200,Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.,ethylene receptor histidine kinase activity,molecular_function
72867,GO:0038201,A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.,TOR complex,cellular_component
72868,GO:0038202,"A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.",TORC1 signaling,biological_process
72869,GO:0038203,"A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.",TORC2 signaling,biological_process
72870,GO:0039003,The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.,pronephric field specification,biological_process
72871,GO:0039004,The process in which the proximal tubule of the pronephric nephron acquires its identity.,specification of pronephric proximal tubule identity,biological_process
72872,GO:0039005,The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.,specification of pronephric tubule identity,biological_process
72873,GO:0039006,The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.,pronephric nephron tubule formation,biological_process
72874,GO:0039007,The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.,pronephric nephron morphogenesis,biological_process
72875,GO:0039008,The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.,pronephric nephron tubule morphogenesis,biological_process
72876,GO:0039009,"The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.",rectal diverticulum development,biological_process
72877,GO:0039010,The process in which the distal tubule of the pronephric nephron acquires its identity.,specification of pronephric distal tubule identity,biological_process
72878,GO:0039011,The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.,pronephric proximal tubule morphogenesis,biological_process
72879,GO:0039012,"The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.",pronephric sinus development,biological_process
72880,GO:0039013,The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.,pronephric distal tubule morphogenesis,biological_process
72881,GO:0039015,"The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.",cell proliferation involved in pronephros development,biological_process
72882,GO:0039018,"The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.",nephrostome development,biological_process
72883,GO:0039019,"The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.",pronephric nephron development,biological_process
72884,GO:0039020,"The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.",pronephric nephron tubule development,biological_process
72885,GO:0039021,The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.,pronephric glomerulus development,biological_process
72886,GO:0039022,"The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.",pronephric duct development,biological_process
72887,GO:0039023,The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.,pronephric duct morphogenesis,biological_process
72888,GO:0039502,"A process in which a symbiont interferes with, inhibits or disrupts a type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",symbiont-mediated suppression of host type I interferon-mediated signaling pathway,biological_process
72889,GO:0039504,"A process by which a symbiont inhibits or disrupts the normal execution of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).",symbiont-mediated suppression of host adaptive immune response,biological_process
72890,GO:0039505,A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class II protein complex.,symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II,biological_process
72891,GO:0039514,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host JAK-STAT cascade,biological_process
72892,GO:0039520,"A process in which a symbiont initiates, promotes, or enhances the normal execution of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. For example, some viruses are able to activate host autophagy as a cellular survival mechanism, hence delaying or inhibiting apoptosis.",symbiont-mediated activation of host autophagy,biological_process
72893,GO:0039522,"A process in which a symbiont inhibits or disrupts the normal movement of mRNA from the nucleus to the cytoplasm of the host cell, leading to shutoff of host protein expression. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host mRNA export from nucleus,biological_process
72894,GO:0039523,A process in which a symbiont inhibits or disrupts the transcription of genes into mRNA in its host by directly inhibiting host RNA polymerase II activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity,biological_process
72895,GO:0039524,A process in which a symbiont inhibits or disrupts mRNA processing in its host. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host mRNA processing,biological_process
72896,GO:0039525,A process in which a symbiont alters or subverts the organization of chromatin in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host chromatin organization,biological_process
72897,GO:0039529,"The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.",RIG-I signaling pathway,biological_process
72898,GO:0039530,"The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.",MDA-5 signaling pathway,biological_process
72899,GO:0039531,"Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway.",regulation of cytoplasmic pattern recognition receptor signaling pathway,biological_process
72900,GO:0039532,"Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway.",negative regulation of cytoplasmic pattern recognition receptor signaling pathway,biological_process
72901,GO:0039533,"Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.",regulation of MDA-5 signaling pathway,biological_process
72902,GO:0039534,"Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway.",negative regulation of MDA-5 signaling pathway,biological_process
72903,GO:0039535,"Any process that modulates the frequency, rate or extent of the RIG-I signaling pathway.",regulation of RIG-I signaling pathway,biological_process
72904,GO:0039536,"Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway.",negative regulation of RIG-I signaling pathway,biological_process
72905,GO:0039537,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway. This is a mechanism by which the virus evades the host innate immune response.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway,biological_process
72906,GO:0039540,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity,biological_process
72907,GO:0039545,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity,biological_process
72908,GO:0039548,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity,biological_process
72909,GO:0039552,"Binding to RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA.",RIG-I binding,molecular_function
72910,GO:0039554,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity,biological_process
72911,GO:0039556,"Binding to MDA-5, a cytoplasmic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA.",MDA-5 binding,molecular_function
72912,GO:0039557,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity,biological_process
72913,GO:0039560,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. For example, viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host IRF9 activity,biological_process
72914,GO:0039562,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity,biological_process
72915,GO:0039563,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1).",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity,biological_process
72916,GO:0039564,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT2 activity,biological_process
72917,GO:0039574,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits.",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity,biological_process
72918,GO:0039576,"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host JAK1 (Janus Kinase 1).",symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity,biological_process
72919,GO:0039579,"Any process in which a symbiont inhibits or disrupts a host ubiquitin-like protein ISG15 conjugation to a substrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. For example, some viruses escape the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15, while the papain-like protease from the coronavirus cl...",symbiont-mediated suppression of host ISG15-protein conjugation,biological_process
72920,GO:0039580,A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host PKR/eIFalpha signaling,biological_process
72921,GO:0039585,"An intracellular signaling cassette that starts with activation and autophosphorylation of PKR (also known as EIF2AK2), which phosphorylates proteins including the translation initiation factor eIF2 to inhibit translation. PKR is activated by stress signals and during the antiviral response, activated by binding to viral double-stranded RNA (dsRNA) leading to inhibition of protein synthesis during viral infection.",PKR/eIFalpha signaling,biological_process
72922,GO:0039587,"Any process in which a symbiont stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.",symbiont-mediated-mediated suppression of host tetherin activity,biological_process
72923,GO:0039588,A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC protein complex.,symbiont-mediated suppression of host antigen processing and presentation,biological_process
72924,GO:0039592,"A process in which a symbiont interferes with the progression of the host mitotic cell cycle from G2 phase to M phase, leading to arrest in G2 phase. The arrest in G2/M allows some viruses to replicate their genome before cells enter mitosis. Alternatively, it can inhibit the antiviral immune response by preventing the clonal expansion of infected lymphocytes.",symbiont-mediated arrest of host cell cycle during G2/M transition,biological_process
72925,GO:0039593,A process in which a virus interferes with the host cell completing the M phase of the cell cycle.,symbiont-mediated perturbation of host exit from mitosis,biological_process
72926,GO:0039595,"The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).",symbiont-mediated degradation of host mRNA,biological_process
72927,GO:0039602,"Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter,biological_process
72928,GO:0039604,"A process in which a symbiont inhibits or disrupts the translation of host mRNA into protein, for example by cleavage of the host mRNAs. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host translation,biological_process
72929,GO:0039606,A process in which a symbiont inhibits or disrupts translation initiation in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host translation initiation,biological_process
72930,GO:0039615,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.,T=1 icosahedral viral capsid,cellular_component
72931,GO:0039616,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.,T=2 icosahedral viral capsid,cellular_component
72932,GO:0039617,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.,T=3 icosahedral viral capsid,cellular_component
72933,GO:0039618,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.,T=pseudo3 icosahedral viral capsid,cellular_component
72934,GO:0039619,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.,T=4 icosahedral viral capsid,cellular_component
72935,GO:0039620,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.,T=7 icosahedral viral capsid,cellular_component
72936,GO:0039621,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres.,T=13 icosahedral viral capsid,cellular_component
72937,GO:0039622,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.,T=16 icosahedral viral capsid,cellular_component
72938,GO:0039623,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.,T=25 icosahedral viral capsid,cellular_component
72939,GO:0039624,The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.,viral outer capsid,cellular_component
72940,GO:0039625,The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.,viral inner capsid,cellular_component
72941,GO:0039626,The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions.,viral intermediate capsid,cellular_component
72942,GO:0039627,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins.,T=147 icosahedral capsid,cellular_component
72943,GO:0039628,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins.,T=169 icosahedral viral capsid,cellular_component
72944,GO:0039629,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins.,T=219 icosahedral capsid,cellular_component
72945,GO:0039630,"Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis.",RNA translocase activity,molecular_function
72946,GO:0039634,The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus.,killing by virus of host cell during superinfection exclusion,biological_process
72947,GO:0039635,"Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls, and phages have mechanisms to disrupt their host's cell walls.",symbiont-mediated suppression of host peptidoglycan biosynthetic process,biological_process
72948,GO:0039636,"Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.",symbiont-mediated suppression of host cell wall biogenesis,biological_process
72949,GO:0039638,The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface.,lipopolysaccharide-mediated virion attachment to host cell,biological_process
72950,GO:0039639,The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.,suppression by virus of host cell lysis in response to superinfection,biological_process
72951,GO:0039640,"The dissemination of mature viral particles from a host cell, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.",viral release via suppression of host peptidoglycan biosynthetic process,biological_process
72952,GO:0039641,The lipid bilayer of a virion contained inside the protein capsid.,viral inner membrane,cellular_component
72953,GO:0039642,The region of a virion in which the nucleic acid is confined.,virion nucleoid,cellular_component
72954,GO:0039643,The region of a host cell that contains the viral genome.,host cell viral nucleoid,cellular_component
72955,GO:0039645,A process in which a symbiont interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint,biological_process
72956,GO:0039646,"A process in which a symbiont interferes with the normal execution of the host cell G0/G1 transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction. Some viruses benefit from keeping cells in resting state (G0), while others favor entry through G1 and subsequent cell division to replicate more efficiently.",symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint,biological_process
72957,GO:0039648,"A process by which a symbiont alters ubiquitin-like protein modification of target proteins of either host or symbiont proteins. This includes ubiquitination, SUMOylation, NEDDylation, and ISG15ylation. The ubiquitination status of a protein  affects whether it is targeted to the proteasome for degradation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host ubiquitin-like protein modification,biological_process
72958,GO:0039653,"A process in which a symbiont inhibits or disrupts transcription of genes into mRNA in its host. For example, symbiont proteins can interfere with host RNA polymerase or with transcription factors. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host transcription,biological_process
72959,GO:0039654,"Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.",fusion of virus membrane with host endosome membrane,biological_process
72960,GO:0039656,A process in which a symbiont alters or subverts the normal execution of host gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to ...,symbiont-mediated perturbation of host gene expression,biological_process
72961,GO:0039657,A process in which a symbiont inhibits or disrupts expression of genes in its host. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an act...,symbiont-mediated suppression of host gene expression,biological_process
72962,GO:0039658,"A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3.",TBK1-IKKE-DDX3 complex,cellular_component
72963,GO:0039660,The action of a molecule that contributes to the structural integrity of a virion.,structural constituent of virion,molecular_function
72964,GO:0039661,"The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.",host organelle outer membrane,cellular_component
72965,GO:0039662,"A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell.",host cell outer membrane,cellular_component
72966,GO:0039663,Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.,membrane fusion involved in viral entry into host cell,biological_process
72967,GO:0039664,"The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm.",lysis of host organelle involved in viral entry into host cell,biological_process
72968,GO:0039665,Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.,permeabilization of host organelle membrane involved in viral entry into host cell,biological_process
72969,GO:0039666,"The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.",virion attachment to host cell pilus,biological_process
72970,GO:0039670,A turret-like appendage formed at the vertices of an icosahedral capsid.,"viral capsid, turret",cellular_component
72971,GO:0039671,A process in which a symbiont alters or subverts the natural killer cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host natural killer cell mediated immune response,biological_process
72972,GO:0039672,"A process in which a symbiont interferes with, inhibits or disrupts natural killer cell activation in the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host natural killer cell activation,biological_process
72973,GO:0039673,A process in which a symbiont inhibits or disrupts the dendritic cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host dendritic cell mediated immune response,biological_process
72974,GO:0039674,The directed movement of the viral genome or a viral particle out of the host cell nucleus.,exit of virus from host cell nucleus,biological_process
72975,GO:0039675,The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.,exit of virus from host cell nucleus through nuclear pore,biological_process
72976,GO:0039677,The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.,exit of virus from host cell nucleus via nuclear envelope disassembly,biological_process
72977,GO:0039678,"Entry of a symbiont's genome into the host cell through the host cell envelope. Occurs in non-enveloped prokaryotic viruses. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.",symbiont genome ejection through host cell envelope,biological_process
72978,GO:0039679,"A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.",viral occlusion body,cellular_component
72979,GO:0039680,"The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.",actin-dependent intracellular transport of virus towards nucleus,biological_process
72980,GO:0039682,"A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.",rolling circle viral DNA replication,biological_process
72981,GO:0039683,A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.,rolling circle double-stranded viral DNA replication,biological_process
72982,GO:0039684,A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.,rolling circle single-stranded viral DNA replication,biological_process
72983,GO:0039685,A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.,rolling hairpin viral DNA replication,biological_process
72984,GO:0039686,"A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.",bidirectional double-stranded viral DNA replication,biological_process
72985,GO:0039687,"A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).",viral DNA strand displacement replication,biological_process
72986,GO:0039688,A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.,viral double stranded DNA replication via reverse transcription,biological_process
72987,GO:0039689,"A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).",negative stranded viral RNA replication,biological_process
72988,GO:0039690,"A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.",positive stranded viral RNA replication,biological_process
72989,GO:0039691,"A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.",double stranded viral RNA replication,biological_process
72990,GO:0039692,"A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.",single stranded viral RNA replication via double stranded DNA intermediate,biological_process
72991,GO:0039693,The replication of a viral DNA genome.,viral DNA genome replication,biological_process
72992,GO:0039694,The replication of a viral RNA genome.,viral RNA genome replication,biological_process
72993,GO:0039695,A transcription process that uses a viral DNA as a template.,DNA-templated viral transcription,biological_process
72994,GO:0039696,A transcription process that uses viral RNA as a template.,RNA-templated viral transcription,biological_process
72995,GO:0039697,A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.,negative stranded viral RNA transcription,biological_process
72996,GO:0039698,"Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.",polyadenylation of viral mRNA by polymerase stuttering,biological_process
72997,GO:0039699,"An innate immune response evasion mechanism in which a symbiont methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. This mechanism of immune evasion is used by viruses.",symbiont-mediated evasion of mRNA degradation by host via mRNA cap methylation,biological_process
72998,GO:0039700,Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.,fusion of viral membrane with host outer nuclear membrane,biological_process
72999,GO:0039701,The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.,microtubule-dependent intracellular transport of viral material towards cell periphery,biological_process
73000,GO:0039702,"Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.",viral budding via host ESCRT complex,biological_process
73001,GO:0039703,The cellular metabolic process in which a cell duplicates one or more molecules of RNA.,RNA replication,biological_process
73002,GO:0039704,A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.,viral translational shunt,biological_process
73003,GO:0039705,"The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.",viral translational readthrough,biological_process
73004,GO:0039706,Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.,co-receptor binding,molecular_function
73005,GO:0039708,The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.,nuclear capsid assembly,biological_process
73006,GO:0039709,The assembly of a virus capsid that occurs in the cytoplasm.,cytoplasmic capsid assembly,biological_process
73007,GO:0039710,The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.,cytoplasmic icosahedral capsid assembly,biological_process
73008,GO:0039711,The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.,cytoplasmic helical capsid assembly,biological_process
73009,GO:0039713,"An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.",viral factory,cellular_component
73010,GO:0039714,A viral factory located in the cytoplasm of a host cell.,cytoplasmic viral factory,cellular_component
73011,GO:0039715,A viral factory located in the nucleus of a host cell.,nuclear viral factory,cellular_component
73012,GO:0039716,"A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.",viroplasm viral factory,cellular_component
73013,GO:0039717,A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus.,spherule viral factory,cellular_component
73014,GO:0039718,"A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae.",double membrane vesicle viral factory,cellular_component
73015,GO:0039719,"A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.",tube viral factory,cellular_component
73016,GO:0039720,A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.,virogenic stroma,cellular_component
73017,GO:0039721,A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.,peristromal region viral factory,cellular_component
73018,GO:0039722,"A process in which a symbiont interferes with, inhibits or disrupts a toll-like receptor signaling pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host toll-like receptor signaling pathway,biological_process
73019,GO:0039723,"Any process in which a symbiont stops, prevents, or reduces a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity,biological_process
73020,GO:0039724,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity,biological_process
73021,GO:0040001,The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.,establishment of mitotic spindle localization,biological_process
73022,GO:0040002,"Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.",collagen and cuticulin-based cuticle development,biological_process
73023,GO:0040003,"Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.",chitin-based cuticle development,biological_process
73024,GO:0040004,Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.,collagen and cuticulin-based cuticle attachment to epithelium,biological_process
73025,GO:0040005,Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.,chitin-based cuticle attachment to epithelium,biological_process
73026,GO:0040007,"The increase in size or mass of an entire organism, a part of an organism or a cell.",growth,biological_process
73027,GO:0040008,"Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.",regulation of growth,biological_process
73028,GO:0040009,Any process that modulates the rate of growth of all or part of an organism.,regulation of growth rate,biological_process
73029,GO:0040010,Any process that increases the rate of growth of all or part of an organism.,positive regulation of growth rate,biological_process
73030,GO:0040011,Self-propelled movement of a cell or organism from one location to another.,locomotion,biological_process
73031,GO:0040012,"Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.",regulation of locomotion,biological_process
73032,GO:0040013,"Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.",negative regulation of locomotion,biological_process
73033,GO:0040014,"Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.",regulation of multicellular organism growth,biological_process
73034,GO:0040015,"Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.",negative regulation of multicellular organism growth,biological_process
73035,GO:0040016,The first few specialized divisions of an activated animal egg.,embryonic cleavage,biological_process
73036,GO:0040017,"Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.",positive regulation of locomotion,biological_process
73037,GO:0040018,"Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.",positive regulation of multicellular organism growth,biological_process
73038,GO:0040019,"Any process that activates or increases the frequency, rate or extent of embryonic development.",positive regulation of embryonic development,biological_process
73039,GO:0040020,"Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.",regulation of meiotic nuclear division,biological_process
73040,GO:0040021,The determination of sex and sexual phenotype in the germ line of a hermaphrodite.,hermaphrodite germ-line sex determination,biological_process
73041,GO:0040022,The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.,feminization of hermaphroditic germ-line,biological_process
73042,GO:0040024,"The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.",dauer larval development,biological_process
73043,GO:0040025,"The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.",vulval development,biological_process
73044,GO:0040026,"Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.",positive regulation of vulval development,biological_process
73045,GO:0040027,"Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.",negative regulation of vulval development,biological_process
73046,GO:0040028,"Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.",regulation of vulval development,biological_process
73047,GO:0040029,"A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal.",epigenetic regulation of gene expression,biological_process
73048,GO:0040031,"The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.",snRNA modification,biological_process
73049,GO:0040032,The process in which the anatomical structures of the post-embryonic soma are generated and organized.,post-embryonic body morphogenesis,biological_process
73050,GO:0040033,A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria.,sRNA-mediated post-transcriptional gene silencing,biological_process
73051,GO:0040034,Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.,"regulation of development, heterochronic",biological_process
73052,GO:0040036,"Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.",regulation of fibroblast growth factor receptor signaling pathway,biological_process
73053,GO:0040037,"Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.",negative regulation of fibroblast growth factor receptor signaling pathway,biological_process
73054,GO:0040038,"The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the...",polar body extrusion after meiotic divisions,biological_process
73055,GO:0040039,"Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.",inductive cell migration,biological_process
73056,GO:0040040,Behavior that is dependent upon the sensation of temperature.,thermosensory behavior,biological_process
73057,GO:0042000,The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,translocation of peptides or proteins into host,biological_process
73058,GO:0042001,The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.,hermaphrodite somatic sex determination,biological_process
73059,GO:0042003,Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.,masculinization of hermaphrodite soma,biological_process
73060,GO:0042004,Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.,feminization of hermaphrodite soma,biological_process
73061,GO:0042006,The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.,masculinization of hermaphroditic germ-line,biological_process
73062,GO:0042007,Binding to interleukin-18.,interleukin-18 binding,molecular_function
73063,GO:0042008,Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-18 receptor activity,molecular_function
73064,GO:0042009,Binding to interleukin-15.,interleukin-15 binding,molecular_function
73065,GO:0042010,Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-15 receptor activity,molecular_function
73066,GO:0042011,Binding to interleukin-16.,interleukin-16 binding,molecular_function
73067,GO:0042012,Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-16 receptor activity,molecular_function
73068,GO:0042013,Binding to interleukin-19.,interleukin-19 binding,molecular_function
73069,GO:0042014,Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-19 receptor activity,molecular_function
73070,GO:0042015,Binding to interleukin-20.,interleukin-20 binding,molecular_function
73071,GO:0042016,Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-20 receptor activity,molecular_function
73072,GO:0042017,Binding to interleukin-22.,interleukin-22 binding,molecular_function
73073,GO:0042018,Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-22 receptor activity,molecular_function
73074,GO:0042019,Binding to interleukin-23.,interleukin-23 binding,molecular_function
73075,GO:0042020,Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-23 receptor activity,molecular_function
73076,GO:0042021,Binding to a granulocyte macrophage colony-stimulating factor complex.,granulocyte macrophage colony-stimulating factor complex binding,molecular_function
73077,GO:0042022,"A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.",interleukin-12 receptor complex,cellular_component
73078,GO:0042023,"Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.",DNA endoreduplication,biological_process
73079,GO:0042025,A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.,host cell nucleus,cellular_component
73080,GO:0042026,"The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.",protein refolding,biological_process
73081,GO:0042030,"Binds to and stops, prevents or reduces an ATP hydrolysis activity.",ATPase inhibitor activity,molecular_function
73082,GO:0042038,"The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine).","peptidyl-histidine methylation, to form tele-methylhistidine",biological_process
73083,GO:0042040,The incorporation of a metal into a metallo-molybdopterin complex.,metal incorporation into metallo-molybdopterin complex,biological_process
73084,GO:0042042,The incorporation of tungsten into a tungsten-molybdopterin complex.,tungsten incorporation into tungsten-molybdopterin complex,biological_process
73085,GO:0042043,"Binding to a neurexin, a synaptic cell surface protein related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.",neurexin family protein binding,molecular_function
73086,GO:0042044,"The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",fluid transport,biological_process
73087,GO:0042045,The directed movement of fluid across epithelia.,epithelial fluid transport,biological_process
73088,GO:0042047,"The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.",W-molybdopterin cofactor biosynthetic process,biological_process
73089,GO:0042048,The behavior of an organism in response to an odor.,olfactory behavior,biological_process
73090,GO:0042049,A homeostatic process involved in the maintenance of a steady state level of acyl-CoA within a cell.,intracellular acyl-CoA homeostasis,biological_process
73091,GO:0042051,"The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.",compound eye photoreceptor development,biological_process
73092,GO:0042052,The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.,rhabdomere development,biological_process
73093,GO:0042053,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.",regulation of dopamine metabolic process,biological_process
73094,GO:0042054,Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or a lysine residue.,histone methyltransferase activity,molecular_function
73095,GO:0042056,Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.,chemoattractant activity,molecular_function
73096,GO:0042058,"Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.",regulation of epidermal growth factor receptor signaling pathway,biological_process
73097,GO:0042059,"Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.",negative regulation of epidermal growth factor receptor signaling pathway,biological_process
73098,GO:0042060,"The series of events that restore integrity to a damaged tissue, following an injury.",wound healing,biological_process
73099,GO:0042062,Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.,long-term strengthening of neuromuscular junction,biological_process
73100,GO:0042063,The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.,gliogenesis,biological_process
73101,GO:0042065,"Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.",glial cell growth,biological_process
73102,GO:0042066,"Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.",perineurial glial growth,biological_process
73103,GO:0042067,The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.,establishment of ommatidial planar polarity,biological_process
73104,GO:0042069,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.",regulation of catecholamine metabolic process,biological_process
73105,GO:0042071,"Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.",leucokinin receptor activity,molecular_function
73106,GO:0042073,"The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.",intraciliary transport,biological_process
73107,GO:0042074,"The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).",cell migration involved in gastrulation,biological_process
73108,GO:0042076,"The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.",protein phosphate-linked glycosylation,biological_process
73109,GO:0042078,"The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.",germ-line stem cell division,biological_process
73110,GO:0042083,"Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.","5,10-methylenetetrahydrofolate-dependent methyltransferase activity",molecular_function
73111,GO:0042086,"Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.","5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity",molecular_function
73112,GO:0042088,"An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.",T-helper 1 type immune response,biological_process
73113,GO:0042092,"An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.",type 2 immune response,biological_process
73114,GO:0042093,The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.,T-helper cell differentiation,biological_process
73115,GO:0042098,The expansion of a T cell population by cell division. Follows T cell activation.,T cell proliferation,biological_process
73116,GO:0042100,The expansion of a B cell population by cell division. Follows B cell activation.,B cell proliferation,biological_process
73117,GO:0042101,"A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.",T cell receptor complex,cellular_component
73118,GO:0042102,Any process that activates or increases the rate or extent of T cell proliferation.,positive regulation of T cell proliferation,biological_process
73119,GO:0042103,Any process that activates or increases the rate or extent of resting T cell proliferation.,positive regulation of T cell homeostatic proliferation,biological_process
73120,GO:0042104,Any process that activates or increases the rate or extent of activated T cell proliferation.,positive regulation of activated T cell proliferation,biological_process
73121,GO:0042105,"A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.",alpha-beta T cell receptor complex,cellular_component
73122,GO:0042106,"A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein.",gamma-delta T cell receptor complex,cellular_component
73123,GO:0042110,"The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",T cell activation,biological_process
73124,GO:0042113,"The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",B cell activation,biological_process
73125,GO:0042116,"A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",macrophage activation,biological_process
73126,GO:0042117,"The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",monocyte activation,biological_process
73127,GO:0042118,"The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",endothelial cell activation,biological_process
73128,GO:0042119,"The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",neutrophil activation,biological_process
73129,GO:0042121,"The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).",alginic acid biosynthetic process,biological_process
73130,GO:0042122,"The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).",alginic acid catabolic process,biological_process
73131,GO:0042123,"Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.",glucanosyltransferase activity,molecular_function
73132,GO:0042124,"Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.","1,3-beta-glucanosyltransferase activity",molecular_function
73133,GO:0042126,"The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.",nitrate metabolic process,biological_process
73134,GO:0042127,"Any process that modulates the frequency, rate or extent of cell proliferation.",regulation of cell population proliferation,biological_process
73135,GO:0042128,"The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.",nitrate assimilation,biological_process
73136,GO:0042129,"Any process that modulates the frequency, rate or extent of T cell proliferation.",regulation of T cell proliferation,biological_process
73137,GO:0042130,"Any process that stops, prevents or reduces the rate or extent of T cell proliferation.",negative regulation of T cell proliferation,biological_process
73138,GO:0042131,Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.,thiamine phosphate phosphatase activity,molecular_function
73139,GO:0042132,"Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.","fructose 1,6-bisphosphate 1-phosphatase activity",molecular_function
73140,GO:0042134,Binding to an unprocessed ribosomal RNA transcript.,rRNA primary transcript binding,molecular_function
73141,GO:0042138,The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.,meiotic DNA double-strand break formation,biological_process
73142,GO:0042139,"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene.",early meiotic recombination nodule assembly,biological_process
73143,GO:0042140,"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over.",late meiotic recombination nodule assembly,biological_process
73144,GO:0042144,The fusion of two vacuole membranes to form a single vacuole.,"vacuole fusion, non-autophagic",biological_process
73145,GO:0042147,The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.,"retrograde transport, endosome to Golgi",biological_process
73146,GO:0042148,"The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.",DNA strand invasion,biological_process
73147,GO:0042149,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.",cellular response to glucose starvation,biological_process
73148,GO:0042150,A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.,plasmid recombination,biological_process
73149,GO:0042151,"An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.",nematocyst,cellular_component
73150,GO:0042152,The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele.,RNA-mediated DNA recombination,biological_process
73151,GO:0042157,"The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.",lipoprotein metabolic process,biological_process
73152,GO:0042158,"The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.",lipoprotein biosynthetic process,biological_process
73153,GO:0042159,"The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.",lipoprotein catabolic process,biological_process
73154,GO:0042160,"The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.",lipoprotein modification,biological_process
73155,GO:0042161,The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group.,lipoprotein oxidation,biological_process
73156,GO:0042162,Any molecular function by which a gene product interacts selectively and non-covalently with a telomeric DNA repeat sequence.,telomeric repeat DNA binding,molecular_function
73157,GO:0042163,Binding to the beta subunit of interleukin-12.,interleukin-12 beta subunit binding,molecular_function
73158,GO:0042164,Binding to the alpha subunit of interleukin-12.,interleukin-12 alpha subunit binding,molecular_function
73159,GO:0042166,"Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.",acetylcholine binding,molecular_function
73160,GO:0042167,"The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.",heme catabolic process,biological_process
73161,GO:0042168,"The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.",heme metabolic process,biological_process
73162,GO:0042169,"Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.",SH2 domain binding,molecular_function
73163,GO:0042170,"Any lipid bilayer that surrounds a plastid or is part of the plastid envelope. Primary plastids (in plants, green algae, red algae, and glaucophytes) are surrounded by two membranes; complex plastids derived from secondary endosymbiosis are surrounded by three or four membranes.",plastid membrane,cellular_component
73164,GO:0042171,Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.,lysophosphatidic acid acyltransferase activity,molecular_function
73165,GO:0042173,"Any process that modulates the frequency, rate or extent of spore formation.",regulation of sporulation resulting in formation of a cellular spore,biological_process
73166,GO:0042174,"Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.",negative regulation of sporulation resulting in formation of a cellular spore,biological_process
73167,GO:0042175,The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.,nuclear outer membrane-endoplasmic reticulum membrane network,cellular_component
73168,GO:0042176,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.",regulation of protein catabolic process,biological_process
73169,GO:0042177,"Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process.",negative regulation of protein catabolic process,biological_process
73170,GO:0042178,"The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organism exposed to it, carried out by individual cells. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",xenobiotic catabolic process,biological_process
73171,GO:0042179,"The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.",nicotine biosynthetic process,biological_process
73172,GO:0042180,"The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.",ketone metabolic process,biological_process
73173,GO:0042181,"The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.",ketone biosynthetic process,biological_process
73174,GO:0042182,"The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.",ketone catabolic process,biological_process
73175,GO:0042183,"The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.",formate catabolic process,biological_process
73176,GO:0042184,"The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.",xylene catabolic process,biological_process
73177,GO:0042185,"The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.",m-xylene catabolic process,biological_process
73178,GO:0042186,"The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.",o-xylene catabolic process,biological_process
73179,GO:0042187,"The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.",p-xylene catabolic process,biological_process
73180,GO:0042188,"The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.","1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process",biological_process
73181,GO:0042189,"The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.",vanillin biosynthetic process,biological_process
73182,GO:0042190,"The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.",vanillin catabolic process,biological_process
73183,GO:0042192,"The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.",methylmercury biosynthetic process,biological_process
73184,GO:0042193,"The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal.",methylmercury catabolic process,biological_process
73185,GO:0042194,"The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid.",quinate biosynthetic process,biological_process
73186,GO:0042197,"The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine.",halogenated hydrocarbon metabolic process,biological_process
73187,GO:0042200,"The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.",cyanuric acid catabolic process,biological_process
73188,GO:0042202,"The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.",N-cyclopropylmelamine catabolic process,biological_process
73189,GO:0042203,"The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.",toluene catabolic process,biological_process
73190,GO:0042204,"The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.",s-triazine compound catabolic process,biological_process
73191,GO:0042205,"The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.",chlorinated hydrocarbon catabolic process,biological_process
73192,GO:0042206,"The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.",halogenated hydrocarbon catabolic process,biological_process
73193,GO:0042207,"The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.",styrene catabolic process,biological_process
73194,GO:0042208,"The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.",propylene catabolic process,biological_process
73195,GO:0042209,"The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.",orcinol catabolic process,biological_process
73196,GO:0042213,"The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.",m-cresol catabolic process,biological_process
73197,GO:0042214,"The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.",terpene metabolic process,biological_process
73198,GO:0042215,"The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.",anaerobic phenol-containing compound metabolic process,biological_process
73199,GO:0042216,"The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.",phenanthrene catabolic process,biological_process
73200,GO:0042217,"The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.",1-aminocyclopropane-1-carboxylate catabolic process,biological_process
73201,GO:0042219,"The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.",modified amino acid catabolic process,biological_process
73202,GO:0042220,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.",response to cocaine,biological_process
73203,GO:0042221,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.",response to chemical,biological_process
73204,GO:0042242,"Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.","cobyrinic acid a,c-diamide synthase activity",molecular_function
73205,GO:0042243,"The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.",asexual spore wall assembly,biological_process
73206,GO:0042244,"The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.",spore wall assembly,biological_process
73207,GO:0042245,Any process that results in the repair of damaged RNA.,RNA repair,biological_process
73208,GO:0042246,The regrowth of lost or destroyed tissues.,tissue regeneration,biological_process
73209,GO:0042247,"Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.",establishment of planar polarity of follicular epithelium,biological_process
73210,GO:0042248,The maintenance of an established polarized follicular epithelial sheet.,maintenance of polarity of follicular epithelium,biological_process
73211,GO:0042249,"Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.",establishment of planar polarity of embryonic epithelium,biological_process
73212,GO:0042250,The maintenance of an established polarized embryonic epithelial sheet.,maintenance of polarity of embryonic epithelium,biological_process
73213,GO:0042251,The maintenance of an established polarized larval imaginal disc epithelium.,maintenance of polarity of larval imaginal disc epithelium,biological_process
73214,GO:0042252,"Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.",establishment of planar polarity of larval imaginal disc epithelium,biological_process
73215,GO:0042254,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.",ribosome biogenesis,biological_process
73216,GO:0042255,"The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.",ribosome assembly,biological_process
73217,GO:0042256,"The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol.",cytosolic ribosome assembly,biological_process
73218,GO:0042262,"Any process in which DNA is protected from damage by, for example, oxidative stress.",DNA protection,biological_process
73219,GO:0042263,"Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.",neuropeptide F receptor activity,molecular_function
73220,GO:0042264,The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.,peptidyl-aspartic acid hydroxylation,biological_process
73221,GO:0042267,The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.,natural killer cell mediated cytotoxicity,biological_process
73222,GO:0042268,"Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.",regulation of cytolysis,biological_process
73223,GO:0042269,"Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.",regulation of natural killer cell mediated cytotoxicity,biological_process
73224,GO:0042270,The process of protecting a cell from natural killer cell mediated cytotoxicity.,protection from natural killer cell mediated cytotoxicity,biological_process
73225,GO:0042271,The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.,susceptibility to natural killer cell mediated cytotoxicity,biological_process
73226,GO:0042272,"A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.",nuclear RNA export factor complex,cellular_component
73227,GO:0042273,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.",ribosomal large subunit biogenesis,biological_process
73228,GO:0042274,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.",ribosomal small subunit biogenesis,biological_process
73229,GO:0042275,"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.",error-free postreplication DNA repair,biological_process
73230,GO:0042276,"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically target...",error-prone translesion synthesis,biological_process
73231,GO:0042277,"Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.",peptide binding,molecular_function
73232,GO:0042278,The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).,purine nucleoside metabolic process,biological_process
73233,GO:0042279,Catalysis of the reaction: 6 Fe(III)-[cytochrome c] + NH4+ + 2 H2O = 6 Fe(II)-[cytochrome c] + nitrite + 8 H+.,"nitrite reductase (cytochrome, ammonia-forming) activity",molecular_function
73234,GO:0042281,Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.,"dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity",molecular_function
73235,GO:0042283,Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.,"dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity",molecular_function
73236,GO:0042284,Catalysis of the reaction: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H+ = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.,sphingolipid delta-4 desaturase activity,molecular_function
73237,GO:0042285,"Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",xylosyltransferase activity,molecular_function
73238,GO:0042286,Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.,"glutamate-1-semialdehyde 2,1-aminomutase activity",molecular_function
73239,GO:0042287,Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.,MHC protein binding,molecular_function
73240,GO:0042288,Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.,MHC class I protein binding,molecular_function
73241,GO:0042289,Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.,MHC class II protein binding,molecular_function
73242,GO:0042292,"Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.",URM1 activating enzyme activity,molecular_function
73243,GO:0042293,"Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.",Hub1 activating enzyme activity,molecular_function
73244,GO:0042294,"Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y = Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages.",URM1 transferase activity,molecular_function
73245,GO:0042296,"Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.",ISG15 transferase activity,molecular_function
73246,GO:0042297,A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.,vocal learning,biological_process
73247,GO:0042299,"Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.",lupeol synthase activity,molecular_function
73248,GO:0042300,"Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin.",beta-amyrin synthase activity,molecular_function
73249,GO:0042301,Binding to a phosphate ion.,phosphate ion binding,molecular_function
73250,GO:0042302,The action of a molecule that contributes to the structural integrity of a cuticle.,structural constituent of cuticle,molecular_function
73251,GO:0042303,"The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.",molting cycle,biological_process
73252,GO:0042304,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.",regulation of fatty acid biosynthetic process,biological_process
73253,GO:0042305,The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,"specification of segmental identity, mandibular segment",biological_process
73254,GO:0042306,"Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.",regulation of protein import into nucleus,biological_process
73255,GO:0042307,"Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.",positive regulation of protein import into nucleus,biological_process
73256,GO:0042308,"Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.",negative regulation of protein import into nucleus,biological_process
73257,GO:0042309,Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment.,homoiothermy,biological_process
73258,GO:0042310,"A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.",vasoconstriction,biological_process
73259,GO:0042311,"An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.",vasodilation,biological_process
73260,GO:0042313,Any process resulting in the inhibition or termination of the activity of protein kinase C.,protein kinase C deactivation,biological_process
73261,GO:0042314,"Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.",bacteriochlorophyll binding,molecular_function
73262,GO:0042316,The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus.,penicillin metabolic process,biological_process
73263,GO:0042317,The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.,penicillin catabolic process,biological_process
73264,GO:0042318,The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.,penicillin biosynthetic process,biological_process
73265,GO:0042320,"Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.","regulation of circadian sleep/wake cycle, REM sleep",biological_process
73266,GO:0042321,"Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.","negative regulation of circadian sleep/wake cycle, sleep",biological_process
73267,GO:0042322,"Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.","negative regulation of circadian sleep/wake cycle, REM sleep",biological_process
73268,GO:0042323,"Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.","negative regulation of circadian sleep/wake cycle, non-REM sleep",biological_process
73269,GO:0042324,Binding to an orexin receptor.,orexin receptor binding,molecular_function
73270,GO:0042325,"Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.",regulation of phosphorylation,biological_process
73271,GO:0042326,"Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.",negative regulation of phosphorylation,biological_process
73272,GO:0042327,"Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.",positive regulation of phosphorylation,biological_process
73273,GO:0042328,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.,heparan sulfate N-acetylglucosaminyltransferase activity,molecular_function
73274,GO:0042329,The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans.,structural constituent of collagen and cuticulin-based cuticle,molecular_function
73275,GO:0042330,The directed movement of a motile cell or organism in response to an external stimulus.,taxis,biological_process
73276,GO:0042331,The directed movement of a motile cell or organism in response to light.,phototaxis,biological_process
73277,GO:0042332,The directed movement of a motile cell or organism in response to gravity.,gravitaxis,biological_process
73278,GO:0042333,"The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.",chemotaxis to oxidizable substrate,biological_process
73279,GO:0042334,"The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.",taxis to electron acceptor,biological_process
73280,GO:0042335,"The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.",cuticle development,biological_process
73281,GO:0042337,"The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.",cuticle development involved in chitin-based cuticle molting cycle,biological_process
73282,GO:0042338,"Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.",cuticle development involved in collagen and cuticulin-based cuticle molting cycle,biological_process
73283,GO:0042339,"The chemical reactions and pathways involving keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated.",keratan sulfate proteoglycan metabolic process,biological_process
73284,GO:0042340,"The chemical reactions and pathways resulting in the breakdown of keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated.",keratan sulfate proteoglycan catabolic process,biological_process
73285,GO:0042342,"The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.",cyanogenic glycoside catabolic process,biological_process
73286,GO:0042343,"The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.",indole glucosinolate metabolic process,biological_process
73287,GO:0042344,"The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.",indole glucosinolate catabolic process,biological_process
73288,GO:0042349,The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.,guiding stereospecific synthesis activity,molecular_function
73289,GO:0042350,"The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.",GDP-L-fucose biosynthetic process,biological_process
73290,GO:0042351,"The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).",'de novo' GDP-L-fucose biosynthetic process,biological_process
73291,GO:0042352,"The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).",GDP-L-fucose salvage,biological_process
73292,GO:0042353,The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).,fucose biosynthetic process,biological_process
73293,GO:0042354,"The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.",L-fucose metabolic process,biological_process
73294,GO:0042355,The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).,L-fucose catabolic process,biological_process
73295,GO:0042356,"Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.",GDP-4-dehydro-D-rhamnose reductase activity,molecular_function
73296,GO:0042357,"The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.",thiamine diphosphate metabolic process,biological_process
73297,GO:0042358,"The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.",thiamine diphosphate catabolic process,biological_process
73298,GO:0042359,"The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",vitamin D metabolic process,biological_process
73299,GO:0042360,"The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.",vitamin E metabolic process,biological_process
73300,GO:0042361,"The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.",menaquinone catabolic process,biological_process
73301,GO:0042362,The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.,fat-soluble vitamin biosynthetic process,biological_process
73302,GO:0042363,The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.,fat-soluble vitamin catabolic process,biological_process
73303,GO:0042364,The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.,water-soluble vitamin biosynthetic process,biological_process
73304,GO:0042365,The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.,water-soluble vitamin catabolic process,biological_process
73305,GO:0042366,"The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.",cobalamin catabolic process,biological_process
73306,GO:0042367,"The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.",biotin catabolic process,biological_process
73307,GO:0042368,"The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",vitamin D biosynthetic process,biological_process
73308,GO:0042369,"The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",vitamin D catabolic process,biological_process
73309,GO:0042370,"The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.",thiamine diphosphate dephosphorylation,biological_process
73310,GO:0042371,"The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.",vitamin K biosynthetic process,biological_process
73311,GO:0042372,"The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.",phylloquinone biosynthetic process,biological_process
73312,GO:0042373,"The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.",vitamin K metabolic process,biological_process
73313,GO:0042376,"The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.",phylloquinone catabolic process,biological_process
73314,GO:0042377,"The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.",vitamin K catabolic process,biological_process
73315,GO:0042379,Binding to a chemokine receptor.,chemokine receptor binding,molecular_function
73316,GO:0042381,"Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.",hemolymph coagulation,biological_process
73317,GO:0042382,"Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.",paraspeckles,cellular_component
73318,GO:0042383,"The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.",sarcolemma,cellular_component
73319,GO:0042385,"A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.",myosin III complex,cellular_component
73320,GO:0042386,"The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.",hemocyte differentiation,biological_process
73321,GO:0042387,"The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.",plasmatocyte differentiation,biological_process
73322,GO:0042388,The series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.,"gibberellic acid mediated signaling pathway, G-alpha-dependent",biological_process
73323,GO:0042389,Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.,omega-3 fatty acid desaturase activity,molecular_function
73324,GO:0042390,The series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.,"gibberellic acid mediated signaling pathway, G-alpha-independent",biological_process
73325,GO:0042391,"Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",regulation of membrane potential,biological_process
73326,GO:0042392,Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.,sphingosine-1-phosphate phosphatase activity,molecular_function
73327,GO:0042393,"Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.",histone binding,molecular_function
73328,GO:0042395,The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.,"ecdysis, collagen and cuticulin-based cuticle",biological_process
73329,GO:0042396,"The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.",phosphagen biosynthetic process,biological_process
73330,GO:0042397,"The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.",phosphagen catabolic process,biological_process
73331,GO:0042398,"The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.",modified amino acid biosynthetic process,biological_process
73332,GO:0042400,"The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.",ectoine catabolic process,biological_process
73333,GO:0042401,"The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.",biogenic amine biosynthetic process,biological_process
73334,GO:0042402,"The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.",biogenic amine catabolic process,biological_process
73335,GO:0042403,"The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.",thyroid hormone metabolic process,biological_process
73336,GO:0042404,"The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.",thyroid hormone catabolic process,biological_process
73337,GO:0042405,An intranuclear focus at which aggregated proteins have been sequestered.,nuclear inclusion body,cellular_component
73338,GO:0042406,"The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of endoplasmic reticulum membrane,cellular_component
73339,GO:0042407,"The assembly of cristae, the inwards folds of the inner mitochondrial membrane.",cristae formation,biological_process
73340,GO:0042409,Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.,caffeoyl-CoA O-methyltransferase activity,molecular_function
73341,GO:0042410,Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H+ + pimelyl-CoA.,6-carboxyhexanoate-CoA ligase activity,molecular_function
73342,GO:0042412,"The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.",taurine biosynthetic process,biological_process
73343,GO:0042413,"The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.",carnitine catabolic process,biological_process
73344,GO:0042414,"The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.",epinephrine metabolic process,biological_process
73345,GO:0042415,"The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.",norepinephrine metabolic process,biological_process
73346,GO:0042416,"The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.",dopamine biosynthetic process,biological_process
73347,GO:0042417,"The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.",dopamine metabolic process,biological_process
73348,GO:0042418,"The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.",epinephrine biosynthetic process,biological_process
73349,GO:0042419,"The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.",epinephrine catabolic process,biological_process
73350,GO:0042420,"The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.",dopamine catabolic process,biological_process
73351,GO:0042421,"The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.",norepinephrine biosynthetic process,biological_process
73352,GO:0042422,"The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.",norepinephrine catabolic process,biological_process
73353,GO:0042423,"The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.",catecholamine biosynthetic process,biological_process
73354,GO:0042424,"The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.",catecholamine catabolic process,biological_process
73355,GO:0042425,"The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.",choline biosynthetic process,biological_process
73356,GO:0042426,"The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.",choline catabolic process,biological_process
73357,GO:0042427,"The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.",serotonin biosynthetic process,biological_process
73358,GO:0042428,"The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.",serotonin metabolic process,biological_process
73359,GO:0042429,"The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.",serotonin catabolic process,biological_process
73360,GO:0042430,"The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.",indole-containing compound metabolic process,biological_process
73361,GO:0042431,"The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).",indole metabolic process,biological_process
73362,GO:0042432,"The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).",indole biosynthetic process,biological_process
73363,GO:0042433,"The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).",indole catabolic process,biological_process
73364,GO:0042435,"The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.",indole-containing compound biosynthetic process,biological_process
73365,GO:0042436,"The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.",indole-containing compound catabolic process,biological_process
73366,GO:0042437,"The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants.",indoleacetic acid catabolic process,biological_process
73367,GO:0042438,"The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.",melanin biosynthetic process,biological_process
73368,GO:0042440,"The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.",pigment metabolic process,biological_process
73369,GO:0042441,"The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.",eye pigment metabolic process,biological_process
73370,GO:0042442,The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).,melatonin catabolic process,biological_process
73371,GO:0042443,"The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.",phenylethylamine metabolic process,biological_process
73372,GO:0042444,"The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.",phenylethylamine biosynthetic process,biological_process
73373,GO:0042445,"The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.",hormone metabolic process,biological_process
73374,GO:0042446,"The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.",hormone biosynthetic process,biological_process
73375,GO:0042447,"The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.",hormone catabolic process,biological_process
73376,GO:0042448,"The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.",progesterone metabolic process,biological_process
73377,GO:0042451,"The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).",purine nucleoside biosynthetic process,biological_process
73378,GO:0042452,"The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.",deoxyguanosine biosynthetic process,biological_process
73379,GO:0042454,"The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",ribonucleoside catabolic process,biological_process
73380,GO:0042455,"The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",ribonucleoside biosynthetic process,biological_process
73381,GO:0042457,"The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.",ethylene catabolic process,biological_process
73382,GO:0042461,"Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.",photoreceptor cell development,biological_process
73383,GO:0042462,"Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.",eye photoreceptor cell development,biological_process
73384,GO:0042463,"Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.",ocellus photoreceptor cell development,biological_process
73385,GO:0042464,"Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.",dosage compensation by hypoactivation of X chromosome,biological_process
73386,GO:0042465,The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus.,kinesis,biological_process
73387,GO:0042466,A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis).,chemokinesis,biological_process
73388,GO:0042467,The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.,orthokinesis,biological_process
73389,GO:0042468,The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered.,klinokinesis,biological_process
73390,GO:0042469,Catalysis of the reduction of versicolorin A to sterigmatocystin.,versicolorin reductase activity,molecular_function
73391,GO:0042470,"A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.",melanosome,cellular_component
73392,GO:0042471,"The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.",ear morphogenesis,biological_process
73393,GO:0042472,"The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.",inner ear morphogenesis,biological_process
73394,GO:0042473,"The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.",outer ear morphogenesis,biological_process
73395,GO:0042474,"The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).",middle ear morphogenesis,biological_process
73396,GO:0042475,"The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.",odontogenesis of dentin-containing tooth,biological_process
73397,GO:0042476,"The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.",odontogenesis,biological_process
73398,GO:0042478,"Any process that modulates the frequency, rate or extent of eye photoreceptor development.",regulation of eye photoreceptor cell development,biological_process
73399,GO:0042479,"Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.",positive regulation of eye photoreceptor cell development,biological_process
73400,GO:0042480,"Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.",negative regulation of eye photoreceptor cell development,biological_process
73401,GO:0042481,"Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.",regulation of odontogenesis,biological_process
73402,GO:0042482,"Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.",positive regulation of odontogenesis,biological_process
73403,GO:0042483,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.",negative regulation of odontogenesis,biological_process
73404,GO:0042487,"Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.",regulation of odontogenesis of dentin-containing tooth,biological_process
73405,GO:0042488,"Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.",positive regulation of odontogenesis of dentin-containing tooth,biological_process
73406,GO:0042489,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.",negative regulation of odontogenesis of dentin-containing tooth,biological_process
73407,GO:0042490,"The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.",mechanoreceptor differentiation,biological_process
73408,GO:0042491,The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.,inner ear auditory receptor cell differentiation,biological_process
73409,GO:0042492,The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.,gamma-delta T cell differentiation,biological_process
73410,GO:0042494,The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs).,detection of bacterial lipoprotein,biological_process
73411,GO:0042495,The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups.,detection of triacyl bacterial lipopeptide,biological_process
73412,GO:0042496,The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups.,detection of diacyl bacterial lipopeptide,biological_process
73413,GO:0042497,Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups.,triacyl lipopeptide binding,molecular_function
73414,GO:0042498,Binding to a lipopeptide containing a nonprotein moiety consisting of two acyl groups.,diacyl lipopeptide binding,molecular_function
73415,GO:0042500,"Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.","aspartic endopeptidase activity, intramembrane cleaving",molecular_function
73416,GO:0042501,The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.,serine phosphorylation of STAT protein,biological_process
73417,GO:0042509,"Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",regulation of tyrosine phosphorylation of STAT protein,biological_process
73418,GO:0042531,"Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",positive regulation of tyrosine phosphorylation of STAT protein,biological_process
73419,GO:0042532,"Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.",negative regulation of tyrosine phosphorylation of STAT protein,biological_process
73420,GO:0042537,"The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.",benzene-containing compound metabolic process,biological_process
73421,GO:0042538,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",hyperosmotic salinity response,biological_process
73422,GO:0042539,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",hypotonic salinity response,biological_process
73423,GO:0042540,"The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids.",hemoglobin catabolic process,biological_process
73424,GO:0042541,"The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.",hemoglobin biosynthetic process,biological_process
73425,GO:0042542,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.",response to hydrogen peroxide,biological_process
73426,GO:0042544,"The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.",melibiose biosynthetic process,biological_process
73427,GO:0042545,"The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.",cell wall modification,biological_process
73428,GO:0042546,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape an...",cell wall biogenesis,biological_process
73429,GO:0042547,The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.,cell wall modification involved in multidimensional cell growth,biological_process
73430,GO:0042548,"Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.","regulation of photosynthesis, light reaction",biological_process
73431,GO:0042549,"The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.",photosystem II stabilization,biological_process
73432,GO:0042550,"The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.",photosystem I stabilization,biological_process
73433,GO:0042551,"A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.",neuron maturation,biological_process
73434,GO:0042552,The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.,myelination,biological_process
73435,GO:0042554,"The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.",superoxide anion generation,biological_process
73436,GO:0042555,A hexameric protein complex required for the initiation and regulation of DNA replication.,MCM complex,cellular_component
73437,GO:0042556,Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.,eukaryotic elongation factor-2 kinase regulator activity,molecular_function
73438,GO:0042557,Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.,eukaryotic elongation factor-2 kinase activator activity,molecular_function
73439,GO:0042558,"The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.",pteridine-containing compound metabolic process,biological_process
73440,GO:0042559,"The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.",pteridine-containing compound biosynthetic process,biological_process
73441,GO:0042560,"The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.",pteridine-containing compound catabolic process,biological_process
73442,GO:0042561,"Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin.",alpha-amyrin synthase activity,molecular_function
73443,GO:0042562,"Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.",hormone binding,molecular_function
73444,GO:0042564,A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.,NLS-dependent protein nuclear import complex,cellular_component
73445,GO:0042565,"A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore.",RNA nuclear export complex,cellular_component
73446,GO:0042566,"A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation.",hydrogenosome,cellular_component
73447,GO:0042567,"A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.",insulin-like growth factor ternary complex,cellular_component
73448,GO:0042568,"A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.",insulin-like growth factor binary complex,cellular_component
73449,GO:0042571,"An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.","immunoglobulin complex, circulating",cellular_component
73450,GO:0042572,"The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.",retinol metabolic process,biological_process
73451,GO:0042573,"The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.",retinoic acid metabolic process,biological_process
73452,GO:0042574,"The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.",retinal metabolic process,biological_process
73453,GO:0042575,A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.,DNA polymerase complex,cellular_component
73454,GO:0042577,Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.,lipid phosphatase activity,molecular_function
73455,GO:0042578,"Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.",phosphoric ester hydrolase activity,molecular_function
73456,GO:0042579,"Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).",microbody,cellular_component
73457,GO:0042580,"A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction.",mannosome,cellular_component
73458,GO:0042581,"Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.",specific granule,cellular_component
73459,GO:0042582,Primary lysosomal granule readily stainable with a Romanowsky stain.,azurophil granule,cellular_component
73460,GO:0042583,"Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.",chromaffin granule,cellular_component
73461,GO:0042584,"The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.",chromaffin granule membrane,cellular_component
73462,GO:0042585,"The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.",germinal vesicle,cellular_component
73463,GO:0042586,Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.,peptide deformylase activity,molecular_function
73464,GO:0042587,"Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.",glycogen granule,cellular_component
73465,GO:0042588,"A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.",zymogen granule,cellular_component
73466,GO:0042589,The lipid bilayer surrounding a zymogen granule.,zymogen granule membrane,cellular_component
73467,GO:0042590,"The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.",antigen processing and presentation of exogenous peptide antigen via MHC class I,biological_process
73468,GO:0042592,Any biological process involved in the maintenance of an internal steady state. Homeostasis allows cells and organisms to maintain stable internal conditions despite varying external conditions.,homeostatic process,biological_process
73469,GO:0042593,Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.,glucose homeostasis,biological_process
73470,GO:0042594,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.",response to starvation,biological_process
73471,GO:0042595,Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.,behavioral response to starvation,biological_process
73472,GO:0042596,The response of an organism to a perceived external threat.,fear response,biological_process
73473,GO:0042597,The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).,periplasmic space,cellular_component
73474,GO:0042599,"A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.",lamellar body,cellular_component
73475,GO:0042600,"A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.",egg chorion,cellular_component
73476,GO:0042601,Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions.,endospore-forming forespore,cellular_component
73477,GO:0042602,Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.,riboflavin reductase (NADPH) activity,molecular_function
73478,GO:0042603,"A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherence, and resistance to desiccation.",capsule,cellular_component
73479,GO:0042605,Binding to an antigen peptide.,peptide antigen binding,molecular_function
73480,GO:0042608,"Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells.",T cell receptor binding,molecular_function
73481,GO:0042609,"Binding to a CD4, a receptor found on the surface of T cells, monocytes and macrophages.",CD4 receptor binding,molecular_function
73482,GO:0042610,"Binding to a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes.",CD8 receptor binding,molecular_function
73483,GO:0042611,"A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.",MHC protein complex,cellular_component
73484,GO:0042612,"A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.",MHC class I protein complex,cellular_component
73485,GO:0042613,"A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.",MHC class II protein complex,cellular_component
73486,GO:0042614,"Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.",CD70 receptor binding,molecular_function
73487,GO:0042615,"Binding to CD154, a receptor found on the surface of some activated lymphocytes.",CD154 receptor binding,molecular_function
73488,GO:0042617,"The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.",paclitaxel biosynthetic process,biological_process
73489,GO:0042618,"The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.",poly-hydroxybutyrate metabolic process,biological_process
73490,GO:0042619,"The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.",poly-hydroxybutyrate biosynthetic process,biological_process
73491,GO:0042620,"The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.",poly(3-hydroxyalkanoate) metabolic process,biological_process
73492,GO:0042621,"The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.",poly(3-hydroxyalkanoate) biosynthetic process,biological_process
73493,GO:0042622,The membrane surrounding the outer segment of a vertebrate photoreceptor.,photoreceptor outer segment membrane,cellular_component
73494,GO:0042625,"Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.",ATPase-coupled ion transmembrane transporter activity,molecular_function
73495,GO:0042626,"Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.",ATPase-coupled transmembrane transporter activity,molecular_function
73496,GO:0042627,"A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.",chylomicron,cellular_component
73497,GO:0042628,The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.,mating plug formation,biological_process
73498,GO:0042629,"Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase.",mast cell granule,cellular_component
73499,GO:0042630,Any process that results in a change in the behavior of an organism as a result of deprivation of water.,behavioral response to water deprivation,biological_process
73500,GO:0042631,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.",cellular response to water deprivation,biological_process
73501,GO:0042632,Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.,cholesterol homeostasis,biological_process
73502,GO:0042633,"The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.",hair cycle,biological_process
73503,GO:0042634,"Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.",regulation of hair cycle,biological_process
73504,GO:0042635,"Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.",positive regulation of hair cycle,biological_process
73505,GO:0042636,"Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.",negative regulation of hair cycle,biological_process
73506,GO:0042637,"The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.",catagen,biological_process
73507,GO:0042638,The shedding phase of the hair cycle.,exogen,biological_process
73508,GO:0042639,The resting phase of hair cycle.,telogen,biological_process
73509,GO:0042640,"The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.",anagen,biological_process
73510,GO:0042641,"Any complex of actin, myosin, and accessory proteins.",actomyosin,cellular_component
73511,GO:0042642,"The myosin part of any complex of actin, myosin, and accessory proteins.","actomyosin, myosin complex part",cellular_component
73512,GO:0042644,The region of a chloroplast to which the DNA is confined.,chloroplast nucleoid,cellular_component
73513,GO:0042645,The region of a mitochondrion to which the DNA is confined.,mitochondrial nucleoid,cellular_component
73514,GO:0042646,The region of a plastid to which the DNA is confined.,plastid nucleoid,cellular_component
73515,GO:0042647,The region of a proplastid to which the DNA is confined.,proplastid nucleoid,cellular_component
73516,GO:0042648,A circular DNA molecule containing chloroplast encoded genes.,chloroplast chromosome,cellular_component
73517,GO:0042649,"Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light.",prothylakoid,cellular_component
73518,GO:0042650,"The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes.",prothylakoid membrane,cellular_component
73519,GO:0042651,The pigmented membrane of any thylakoid.,thylakoid membrane,cellular_component
73520,GO:0042654,Combining with ecdysis-triggering hormone to initiate a change in cell activity.,ecdysis-triggering hormone receptor activity,molecular_function
73521,GO:0042656,Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).,JUN kinase kinase kinase kinase activity,molecular_function
73522,GO:0042657,Binding to the lateral surface of major histocompatibility complex class II molecules.,"MHC class II protein binding, via lateral surface",molecular_function
73523,GO:0042658,Binding to the antigen binding groove of major histocompatibility complex class II molecules.,"MHC class II protein binding, via antigen binding groove",molecular_function
73524,GO:0042659,Any process that mediates the adoption of a specific fate by a cell.,regulation of cell fate specification,biological_process
73525,GO:0042660,Any process that activates or enables a cell to adopt a specific fate.,positive regulation of cell fate specification,biological_process
73526,GO:0042661,"Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.",regulation of mesodermal cell fate specification,biological_process
73527,GO:0042662,"Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.",negative regulation of mesodermal cell fate specification,biological_process
73528,GO:0042663,Any process that mediates the specification of a cell into an endoderm cell.,regulation of endodermal cell fate specification,biological_process
73529,GO:0042664,"Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.",negative regulation of endodermal cell fate specification,biological_process
73530,GO:0042665,Any process that mediates the specification of a cell into an ectoderm cell.,regulation of ectodermal cell fate specification,biological_process
73531,GO:0042666,"Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.",negative regulation of ectodermal cell fate specification,biological_process
73532,GO:0042667,"The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",auditory receptor cell fate specification,biological_process
73533,GO:0042668,"The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.",auditory receptor cell fate determination,biological_process
73534,GO:0042669,Any process that mediates the specification of a cell into an auditory hair cell.,regulation of inner ear auditory receptor cell fate specification,biological_process
73535,GO:0042670,The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.,retinal cone cell differentiation,biological_process
73536,GO:0042671,"The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.",retinal cone cell fate determination,biological_process
73537,GO:0042672,"The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",retinal cone cell fate specification,biological_process
73538,GO:0042673,Any process that mediates the specification of a cell into a retinal cone cell.,regulation of retinal cone cell fate specification,biological_process
73539,GO:0042675,"The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.",compound eye cone cell differentiation,biological_process
73540,GO:0042676,"The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.",compound eye cone cell fate commitment,biological_process
73541,GO:0042679,"The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",compound eye cone cell fate specification,biological_process
73542,GO:0042680,"The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.",compound eye cone cell fate determination,biological_process
73543,GO:0042682,Any process that mediates the specification of a cell into a compound eye cone cell.,regulation of compound eye cone cell fate specification,biological_process
73544,GO:0042683,"Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.",negative regulation of compound eye cone cell fate specification,biological_process
73545,GO:0042684,"The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast cell fate commitment,biological_process
73546,GO:0042685,"The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast cell fate specification,biological_process
73547,GO:0042686,"Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",regulation of cardioblast cell fate specification,biological_process
73548,GO:0042688,"The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.",crystal cell differentiation,biological_process
73549,GO:0042689,"Any process that modulates the frequency, rate or extent of crystal cell differentiation.",regulation of crystal cell differentiation,biological_process
73550,GO:0042690,"Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.",negative regulation of crystal cell differentiation,biological_process
73551,GO:0042691,"Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.",positive regulation of crystal cell differentiation,biological_process
73552,GO:0042692,The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.,muscle cell differentiation,biological_process
73553,GO:0042693,The process in which the cellular identity of muscle cells is acquired and determined.,muscle cell fate commitment,biological_process
73554,GO:0042694,"The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",muscle cell fate specification,biological_process
73555,GO:0042695,The beginning of development of the breasts in the female.,thelarche,biological_process
73556,GO:0042696,The beginning of the menstrual cycle; the first menstrual cycle in an individual.,menarche,biological_process
73557,GO:0042697,"Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.",menopause,biological_process
73558,GO:0042698,"The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.",ovulation cycle,biological_process
73559,GO:0042699,"A G protein-coupled receptor signaling pathway initiated by follicle-stimulating hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",follicle-stimulating hormone signaling pathway,biological_process
73560,GO:0042700,"A G protein-coupled receptor signaling pathway initiated by luteinizing hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",luteinizing hormone signaling pathway,biological_process
73561,GO:0042701,"The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.",progesterone secretion,biological_process
73562,GO:0042702,"The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.",uterine wall growth,biological_process
73563,GO:0042703,"The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.",menstruation,biological_process
73564,GO:0042704,The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.,uterine wall breakdown,biological_process
73565,GO:0042705,The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.,ocellus photoreceptor cell differentiation,biological_process
73566,GO:0042706,The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.,eye photoreceptor cell fate commitment,biological_process
73567,GO:0042707,The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.,ocellus photoreceptor cell fate commitment,biological_process
73568,GO:0042709,"A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.",succinate-CoA ligase complex,cellular_component
73569,GO:0042710,"A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",biofilm formation,biological_process
73570,GO:0042711,Female behaviors associated with the care and rearing of offspring.,maternal behavior,biological_process
73571,GO:0042712,Male behaviors associated with the care and rearing offspring.,paternal behavior,biological_process
73572,GO:0042713,"The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.",sperm ejaculation,biological_process
73573,GO:0042714,"The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.",dosage compensation complex assembly,biological_process
73574,GO:0042716,"A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria.",plasma membrane-derived chromatophore,cellular_component
73575,GO:0042717,The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles.,plasma membrane-derived chromatophore membrane,cellular_component
73576,GO:0042718,"Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.",yolk granule,cellular_component
73577,GO:0042719,mitochondrial protein-containing complex localised in the mitochondrial inner membrane space that chaperones proteins to the TIM22 complex for insertion into the mitochondrial inner membrane.,mitochondrial intermembrane space chaperone complex,cellular_component
73578,GO:0042720,"Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.",mitochondrial inner membrane peptidase complex,cellular_component
73579,GO:0042721,"A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.",TIM22 mitochondrial import inner membrane insertion complex,cellular_component
73580,GO:0042722,"The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.",alpha-beta T cell activation by superantigen,biological_process
73581,GO:0042723,"The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.",thiamine-containing compound metabolic process,biological_process
73582,GO:0042724,"The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.",thiamine-containing compound biosynthetic process,biological_process
73583,GO:0042725,"The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.",thiamine-containing compound catabolic process,biological_process
73584,GO:0042726,"The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.",flavin-containing compound metabolic process,biological_process
73585,GO:0042727,"The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.",flavin-containing compound biosynthetic process,biological_process
73586,GO:0042728,"The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.",flavin-containing compound catabolic process,biological_process
73587,GO:0042729,"A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.",DASH complex,cellular_component
73588,GO:0042730,"A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.",fibrinolysis,biological_process
73589,GO:0042731,"Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.",PH domain binding,molecular_function
73590,GO:0042732,"The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.",D-xylose metabolic process,biological_process
73591,GO:0042733,"The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.",embryonic digit morphogenesis,biological_process
73592,GO:0042734,"A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.",presynaptic membrane,cellular_component
73593,GO:0042735,"A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins.",endosperm protein body,cellular_component
73594,GO:0042736,Catalysis of the reaction: ATP + NADH = ADP + 2 H+ + NADPH.,NADH kinase activity,molecular_function
73595,GO:0042740,The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.,exogenous antibiotic catabolic process,biological_process
73596,GO:0042741,The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.,endogenous antibiotic catabolic process,biological_process
73597,GO:0042742,Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.,defense response to bacterium,biological_process
73598,GO:0042743,"The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.",hydrogen peroxide metabolic process,biological_process
73599,GO:0042744,The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).,hydrogen peroxide catabolic process,biological_process
73600,GO:0042745,The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.,circadian sleep/wake cycle,biological_process
73601,GO:0042746,The part of the circadian sleep/wake cycle where the organism is not asleep.,"circadian sleep/wake cycle, wakefulness",biological_process
73602,GO:0042747,"A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.","circadian sleep/wake cycle, REM sleep",biological_process
73603,GO:0042748,All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.,"circadian sleep/wake cycle, non-REM sleep",biological_process
73604,GO:0042749,"Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.",regulation of circadian sleep/wake cycle,biological_process
73605,GO:0042750,Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.,hibernation,biological_process
73606,GO:0042751,"Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.",estivation,biological_process
73607,GO:0042752,"Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.",regulation of circadian rhythm,biological_process
73608,GO:0042753,"Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.",positive regulation of circadian rhythm,biological_process
73609,GO:0042754,"Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.",negative regulation of circadian rhythm,biological_process
73610,GO:0042755,"The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.",eating behavior,biological_process
73611,GO:0042756,"The specific behavior of an organism relating to the intake of liquids, especially water.",drinking behavior,biological_process
73612,GO:0042757,"Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses.",giant axon,cellular_component
73613,GO:0042758,The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid catabolic process,biological_process
73614,GO:0042759,The chemical reactions and pathways resulting in the formation of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid biosynthetic process,biological_process
73615,GO:0042760,The chemical reactions and pathways resulting in the breakdown of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acid catabolic process,biological_process
73616,GO:0042761,The chemical reactions and pathways resulting in the formation of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acid biosynthetic process,biological_process
73617,GO:0042762,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.",regulation of sulfur metabolic process,biological_process
73618,GO:0042763,"A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants.",intracellular immature spore,cellular_component
73619,GO:0042764,"An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.",ascospore-type prospore,cellular_component
73620,GO:0042765,"An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.",GPI-anchor transamidase complex,cellular_component
73621,GO:0042767,"Catalysis of the reaction: 3-dehydro-2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H+ = 3-dehydro-2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O. Other substrates include 3-dehydro-2,22,25-deoxyecdysone and 2,22-dideoxyecdysone.",ecdysteroid 22-hydroxylase activity,molecular_function
73622,GO:0042768,Catalysis of the hydroxylation of an ecdysteroid at carbon position 2.,ecdysteroid 2-hydroxylase activity,molecular_function
73623,GO:0042770,A cascade of processes induced by the detection of DNA damage within a cell.,signal transduction in response to DNA damage,biological_process
73624,GO:0042771,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,biological_process
73625,GO:0042772,"A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.","DNA damage response, signal transduction resulting in transcription",biological_process
73626,GO:0042773,"The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.",ATP synthesis coupled electron transport,biological_process
73627,GO:0042774,"The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane.",plasma membrane ATP synthesis coupled electron transport,biological_process
73628,GO:0042775,"The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.",mitochondrial ATP synthesis coupled electron transport,biological_process
73629,GO:0042776,The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force).,proton motive force-driven mitochondrial ATP synthesis,biological_process
73630,GO:0042777,The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a plasma membrane to generate an electrochemical gradient (proton-motive force).,proton motive force-driven plasma membrane ATP synthesis,biological_process
73631,GO:0042778,The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.,tRNA end turnover,biological_process
73632,GO:0042780,The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.,tRNA 3'-end processing,biological_process
73633,GO:0042781,"Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.",3'-tRNA processing endoribonuclease activity,molecular_function
73634,GO:0042783,A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated evasion of host immune response,biological_process
73635,GO:0042784,A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host complement activation,biological_process
73636,GO:0042789,"The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.",mRNA transcription by RNA polymerase II,biological_process
73637,GO:0042790,"The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.",nucleolar large rRNA transcription by RNA polymerase I,biological_process
73638,GO:0042791,"The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.",5S class rRNA transcription by RNA polymerase III,biological_process
73639,GO:0042793,"The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.",plastid transcription,biological_process
73640,GO:0042794,"The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.",plastid rRNA transcription,biological_process
73641,GO:0042795,"The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.",snRNA transcription by RNA polymerase II,biological_process
73642,GO:0042796,"The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.",snRNA transcription by RNA polymerase III,biological_process
73643,GO:0042797,"The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.",tRNA transcription by RNA polymerase III,biological_process
73644,GO:0042799,Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.,histone H4K20 methyltransferase activity,molecular_function
73645,GO:0042800,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of up to three methyl groups to the lysine residue at position 4 of the histone H3 protein.,histone H3K4 methyltransferase activity,molecular_function
73646,GO:0042802,Binding to an identical protein or proteins.,identical protein binding,molecular_function
73647,GO:0042803,Binding to an identical protein to form a homodimer.,protein homodimerization activity,molecular_function
73648,GO:0042805,"Binding to actinin, any member of a family of proteins that crosslink F-actin.",actinin binding,molecular_function
73649,GO:0042806,"Binding to fucose, the pentose 6-deoxygalactose.",fucose binding,molecular_function
73650,GO:0042807,"A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.",central vacuole,cellular_component
73651,GO:0042809,"Binding to a nuclear vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.",nuclear vitamin D receptor binding,molecular_function
73652,GO:0042810,"The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.",pheromone metabolic process,biological_process
73653,GO:0042811,"The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.",pheromone biosynthetic process,biological_process
73654,GO:0042812,"The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.",pheromone catabolic process,biological_process
73655,GO:0042813,Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.,Wnt receptor activity,molecular_function
73656,GO:0042814,Polarized growth from one end of a cell.,monopolar cell growth,biological_process
73657,GO:0042815,"The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.",bipolar cell growth,biological_process
73658,GO:0042816,"The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.",vitamin B6 metabolic process,biological_process
73659,GO:0042817,"The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxal metabolic process,biological_process
73660,GO:0042818,"The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.",pyridoxamine metabolic process,biological_process
73661,GO:0042819,"The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.",vitamin B6 biosynthetic process,biological_process
73662,GO:0042820,"The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.",vitamin B6 catabolic process,biological_process
73663,GO:0042821,"The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.",pyridoxal biosynthetic process,biological_process
73664,GO:0042822,"The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.",pyridoxal 5'-phosphate metabolic process,biological_process
73665,GO:0042823,"The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.",pyridoxal 5'-phosphate biosynthetic process,biological_process
73666,GO:0042824,"A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.",MHC class I peptide loading complex,cellular_component
73667,GO:0042825,A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.,TAP complex,cellular_component
73668,GO:0042826,Binding to histone deacetylase.,histone deacetylase binding,molecular_function
73669,GO:0042827,"Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.",platelet dense granule,cellular_component
73670,GO:0042832,Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.,defense response to protozoan,biological_process
73671,GO:0042834,"Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.",peptidoglycan binding,molecular_function
73672,GO:0042835,Binding to a BRE RNA element (Bruno response element).,BRE binding,molecular_function
73673,GO:0042836,"The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.",D-glucarate metabolic process,biological_process
73674,GO:0042837,"The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.",D-glucarate biosynthetic process,biological_process
73675,GO:0042838,"The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.",D-glucarate catabolic process,biological_process
73676,GO:0042840,"The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.",D-glucuronate catabolic process,biological_process
73677,GO:0042841,"The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.",D-glucuronate biosynthetic process,biological_process
73678,GO:0042842,"The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.",D-xylose biosynthetic process,biological_process
73679,GO:0042843,"The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.",D-xylose catabolic process,biological_process
73680,GO:0042844,"The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.",glycol metabolic process,biological_process
73681,GO:0042845,"The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.",glycol biosynthetic process,biological_process
73682,GO:0042846,"The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.",glycol catabolic process,biological_process
73683,GO:0042849,"The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.",L-sorbose biosynthetic process,biological_process
73684,GO:0042850,"The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.",L-sorbose catabolic process,biological_process
73685,GO:0042852,"The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.",L-alanine biosynthetic process,biological_process
73686,GO:0042853,The chemical reactions and pathways resulting in the breakdown of L-alanine.,L-alanine catabolic process,biological_process
73687,GO:0042854,"The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.",eugenol metabolic process,biological_process
73688,GO:0042855,"The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.",eugenol biosynthetic process,biological_process
73689,GO:0042856,"The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.",eugenol catabolic process,biological_process
73690,GO:0042858,"The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).",chrysobactin biosynthetic process,biological_process
73691,GO:0042859,"The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).",chrysobactin catabolic process,biological_process
73692,GO:0042861,"The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.",achromobactin biosynthetic process,biological_process
73693,GO:0042862,"The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.",achromobactin catabolic process,biological_process
73694,GO:0042864,The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).,pyochelin biosynthetic process,biological_process
73695,GO:0042865,The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).,pyochelin catabolic process,biological_process
73696,GO:0042866,"The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.",pyruvate biosynthetic process,biological_process
73697,GO:0042867,"The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.",pyruvate catabolic process,biological_process
73698,GO:0042868,"The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.",antisense RNA metabolic process,biological_process
73699,GO:0042869,"The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other.",aldarate transmembrane transport,biological_process
73700,GO:0042870,"The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other.",D-glucarate transmembrane transport,biological_process
73701,GO:0042873,"The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other.",aldonate transmembrane transport,biological_process
73702,GO:0042874,"The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other.",D-glucuronate transmembrane transport,biological_process
73703,GO:0042875,"The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other.",D-galactonate transmembrane transport,biological_process
73704,GO:0042876,Enables the transfer of aldarate from one side of a membrane to the other.,aldarate transmembrane transporter activity,molecular_function
73705,GO:0042878,"Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other.",D-glucarate transmembrane transporter activity,molecular_function
73706,GO:0042879,Enables the transfer of aldonate from one side of a membrane to the other.,aldonate transmembrane transporter activity,molecular_function
73707,GO:0042880,"Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.",D-glucuronate transmembrane transporter activity,molecular_function
73708,GO:0042881,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-galactonate(out) + H+(out) = D-galactonate(in) + H+(in).,D-galactonate:proton symporter activity,molecular_function
73709,GO:0042882,"The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.",L-arabinose transmembrane transport,biological_process
73710,GO:0042883,"The directed movement of L-cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-cysteine transport,biological_process
73711,GO:0042884,"The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",microcin transport,biological_process
73712,GO:0042885,"The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",microcin B17 transport,biological_process
73713,GO:0042888,Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other.,molybdenum ion transmembrane transporter activity,molecular_function
73714,GO:0042892,"The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other.",chloramphenicol transmembrane transport,biological_process
73715,GO:0042893,"The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",polymyxin transport,biological_process
73716,GO:0042894,"The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",fosmidomycin transport,biological_process
73717,GO:0042896,"Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other.",chloramphenicol transmembrane transporter activity,molecular_function
73718,GO:0042897,"Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.",polymyxin transmembrane transporter activity,molecular_function
73719,GO:0042898,"Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.",fosmidomycin transmembrane transporter activity,molecular_function
73720,GO:0042899,"The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other.",arabinan transmembrane transport,biological_process
73721,GO:0042900,"Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other.",arabinose transmembrane transporter activity,molecular_function
73722,GO:0042901,"Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other.",arabinan transmembrane transporter activity,molecular_function
73723,GO:0042903,Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.,tubulin deacetylase activity,molecular_function
73724,GO:0042904,"The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.",9-cis-retinoic acid biosynthetic process,biological_process
73725,GO:0042905,"The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.",9-cis-retinoic acid metabolic process,biological_process
73726,GO:0042906,"The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.",xanthine transport,biological_process
73727,GO:0042907,"Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.",xanthine transmembrane transporter activity,molecular_function
73728,GO:0042908,"The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",xenobiotic transport,biological_process
73729,GO:0042910,Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.,xenobiotic transmembrane transporter activity,molecular_function
73730,GO:0042912,"Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.",colicin transmembrane transporter activity,molecular_function
73731,GO:0042913,"Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other.",group A colicin transmembrane transporter activity,molecular_function
73732,GO:0042914,"The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.",colicin transport,biological_process
73733,GO:0042915,"The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",group A colicin transport,biological_process
73734,GO:0042918,"The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical.",alkanesulfonate transmembrane transport,biological_process
73735,GO:0042919,"The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",benzoate transport,biological_process
73736,GO:0042920,"The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other.",3-hydroxyphenylpropionic acid transmembrane transport,biological_process
73737,GO:0042921,"A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated glucocorticoid signaling pathway,biological_process
73738,GO:0042922,Binding to one or more specific sites on a neuromedin U receptor.,neuromedin U receptor binding,molecular_function
73739,GO:0042923,"Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).",neuropeptide binding,molecular_function
73740,GO:0042924,"Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.",neuromedin U binding,molecular_function
73741,GO:0042925,"Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.",benzoate transmembrane transporter activity,molecular_function
73742,GO:0042926,Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other.,3-hydroxyphenylpropionic acid transmembrane transporter activity,molecular_function
73743,GO:0042928,A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.,ferrichrome import into cell,biological_process
73744,GO:0042929,Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.,ferrichrome transmembrane transporter activity,molecular_function
73745,GO:0042930,"The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",enterobactin transport,biological_process
73746,GO:0042931,"Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.",enterobactin transmembrane transporter activity,molecular_function
73747,GO:0042932,"The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",chrysobactin transport,biological_process
73748,GO:0042933,"Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.",chrysobactin transmembrane transporter activity,molecular_function
73749,GO:0042934,"Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other.",achromobactin transmembrane transporter activity,molecular_function
73750,GO:0042935,"The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",achromobactin transport,biological_process
73751,GO:0042937,"Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.",tripeptide transmembrane transporter activity,molecular_function
73752,GO:0042938,"The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",dipeptide transport,biological_process
73753,GO:0042939,"The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tripeptide transport,biological_process
73754,GO:0042940,"The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",D-amino acid transport,biological_process
73755,GO:0042941,"The process in which D-alanine, the D-enantiomer of 2-aminopropanoic acid,  is transported across a lipid bilayer, from one side of a membrane to the other by means of some agent such as a transporter or pore.",D-alanine transmembrane transport,biological_process
73756,GO:0042942,"The process in which of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore.",D-serine transmembrane transport,biological_process
73757,GO:0042943,Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.,D-amino acid transmembrane transporter activity,molecular_function
73758,GO:0042944,Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.,D-alanine transmembrane transporter activity,molecular_function
73759,GO:0042945,Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.,D-serine transmembrane transporter activity,molecular_function
73760,GO:0042946,"The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.",glucoside transport,biological_process
73761,GO:0042947,Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.,glucoside transmembrane transporter activity,molecular_function
73762,GO:0042948,"The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",salicin transport,biological_process
73763,GO:0042949,"The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",arbutin transport,biological_process
73764,GO:0042950,"Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other.",salicin transmembrane transporter activity,molecular_function
73765,GO:0042951,"Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.",arbutin transmembrane transporter activity,molecular_function
73766,GO:0042952,"A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.",beta-ketoadipate pathway,biological_process
73767,GO:0042953,"The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lipoprotein transport,biological_process
73768,GO:0042955,"The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",dextrin transport,biological_process
73769,GO:0042956,"The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane.",maltodextrin transmembrane transport,biological_process
73770,GO:0042957,"Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.",dextrin transmembrane transporter activity,molecular_function
73771,GO:0042958,"Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other.",maltodextrin transmembrane transporter activity,molecular_function
73772,GO:0042959,Enables the transfer of an alkanesulfonate from one side of a membrane to the other according to the reaction: ATP + H2O + alkanesulfonate(out) = ADP + phosphate + alkanesulfonate(in).,ABC-type alkanesulfonate transporter transporter activity,molecular_function
73773,GO:0042960,"Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",antimonite secondary active transmembrane transporter activity,molecular_function
73774,GO:0042961,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).,ATPase-coupled antimonite transmembrane transporter activity,molecular_function
73775,GO:0042962,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).,acridine:proton antiporter activity,molecular_function
73776,GO:0042966,"The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase.",biotin carboxyl carrier protein biosynthetic process,biological_process
73777,GO:0042968,"The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-homoserine transmembrane transport,biological_process
73778,GO:0042970,"Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.",L-homoserine transmembrane transporter activity,molecular_function
73779,GO:0042972,Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.,licheninase activity,molecular_function
73780,GO:0042973,Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.,"glucan endo-1,3-beta-D-glucosidase activity",molecular_function
73781,GO:0042974,"Binding to a nuclear retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.",nuclear retinoic acid receptor binding,molecular_function
73782,GO:0042975,"Binding to a peroxisome proliferator activated receptor, alpha, beta or gamma.",peroxisome proliferator activated receptor binding,molecular_function
73783,GO:0042976,"The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.",activation of Janus kinase activity,biological_process
73784,GO:0042978,Binds to and increases ornithine decarboxylase activity.,ornithine decarboxylase activator activity,molecular_function
73785,GO:0042979,Binds to and modulates the activity of the enzyme ornithine decarboxylase.,ornithine decarboxylase regulator activity,molecular_function
73786,GO:0042981,Any process that modulates the occurrence or rate of cell death by apoptotic process.,regulation of apoptotic process,biological_process
73787,GO:0042982,"The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.",amyloid precursor protein metabolic process,biological_process
73788,GO:0042983,"The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.",amyloid precursor protein biosynthetic process,biological_process
73789,GO:0042984,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.",regulation of amyloid precursor protein biosynthetic process,biological_process
73790,GO:0042985,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.",negative regulation of amyloid precursor protein biosynthetic process,biological_process
73791,GO:0042986,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.",positive regulation of amyloid precursor protein biosynthetic process,biological_process
73792,GO:0042987,"The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.",amyloid precursor protein catabolic process,biological_process
73793,GO:0042988,"Binding to X11-like protein, a neuron-specific adaptor protein.",X11-like protein binding,molecular_function
73794,GO:0042995,"A prolongation or process extending from a cell, e.g. a flagellum or axon.",cell projection,cellular_component
73795,GO:0042996,"Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.",regulation of Golgi to plasma membrane protein transport,biological_process
73796,GO:0042997,"Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.",negative regulation of Golgi to plasma membrane protein transport,biological_process
73797,GO:0042998,"Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.",positive regulation of Golgi to plasma membrane protein transport,biological_process
73798,GO:0043001,The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. Golgi to plasma membrane transport precedes exocytosis.,Golgi to plasma membrane protein transport,biological_process
73799,GO:0043005,"A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.",neuron projection,cellular_component
73800,GO:0043007,Any process involved in sustaining the fidelity and copy number of rDNA repeats.,maintenance of rDNA,biological_process
73801,GO:0043008,Binding to a protein or protein complex using energy from ATP hydrolysis.,ATP-dependent protein binding,molecular_function
73802,GO:0043009,"The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.",chordate embryonic development,biological_process
73803,GO:0043010,"The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.",camera-type eye development,biological_process
73804,GO:0043011,"The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.",myeloid dendritic cell differentiation,biological_process
73805,GO:0043012,Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.,regulation of fusion of sperm to egg plasma membrane,biological_process
73806,GO:0043013,Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.,negative regulation of fusion of sperm to egg plasma membrane,biological_process
73807,GO:0043014,Binding to the microtubule constituent protein alpha-tubulin.,alpha-tubulin binding,molecular_function
73808,GO:0043015,Binding to the microtubule constituent protein gamma-tubulin.,gamma-tubulin binding,molecular_function
73809,GO:0043020,"A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.",NADPH oxidase complex,cellular_component
73810,GO:0043021,Binding to a complex of RNA and protein.,ribonucleoprotein complex binding,molecular_function
73811,GO:0043022,Binding to a ribosome.,ribosome binding,molecular_function
73812,GO:0043023,Binding to a large ribosomal subunit.,ribosomal large subunit binding,molecular_function
73813,GO:0043024,Binding to a small ribosomal subunit.,ribosomal small subunit binding,molecular_function
73814,GO:0043025,"The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.",neuronal cell body,cellular_component
73815,GO:0043027,"Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.",cysteine-type endopeptidase inhibitor activity involved in apoptotic process,molecular_function
73816,GO:0043028,Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.,cysteine-type endopeptidase regulator activity involved in apoptotic process,molecular_function
73817,GO:0043029,The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,T cell homeostasis,biological_process
73818,GO:0043030,Any process that modulates the frequency or rate of macrophage activation.,regulation of macrophage activation,biological_process
73819,GO:0043031,"Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.",negative regulation of macrophage activation,biological_process
73820,GO:0043032,"Any process that stimulates, induces or increases the rate of macrophage activation.",positive regulation of macrophage activation,biological_process
73821,GO:0043033,"A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages.",isoamylase complex,cellular_component
73822,GO:0043034,"Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.",costamere,cellular_component
73823,GO:0043035,"Binding to a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.",chromatin insulator sequence binding,molecular_function
73824,GO:0043036,"Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.",starch grain,cellular_component
73825,GO:0043038,"The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.",amino acid activation,biological_process
73826,GO:0043039,"The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.",tRNA aminoacylation,biological_process
73827,GO:0043040,"The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis.",tRNA aminoacylation for nonribosomal peptide biosynthetic process,biological_process
73828,GO:0043041,Activation of an amino acid for incorporation into a peptide by a nonribosomal process.,amino acid activation for nonribosomal peptide biosynthetic process,biological_process
73829,GO:0043042,"Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.",amino acid adenylylation by nonribosomal peptide synthase,biological_process
73830,GO:0043043,"The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.",peptide biosynthetic process,biological_process
73831,GO:0043045,"A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation.",epigenetic programming of gene expression,biological_process
73832,GO:0043047,Binding to single-stranded telomere-associated DNA.,single-stranded telomeric DNA binding,molecular_function
73833,GO:0043048,"The chemical reactions and pathways resulting in the formation of dolichyl monophosphate, a phosphorylated dolichol derivative.",dolichyl monophosphate biosynthetic process,biological_process
73834,GO:0043049,The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.,otic placode formation,biological_process
73835,GO:0043050,The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.,nematode pharyngeal pumping,biological_process
73836,GO:0043051,Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.,regulation of nematode pharyngeal pumping,biological_process
73837,GO:0043052,The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.,thermotaxis,biological_process
73838,GO:0043053,Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.,dauer entry,biological_process
73839,GO:0043054,Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.,dauer exit,biological_process
73840,GO:0043055,Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development.,maintenance of dauer,biological_process
73841,GO:0043056,"Anterior movement of an organism, following the direction of the head of the animal.",forward locomotion,biological_process
73842,GO:0043057,"Posterior movement of an organism, e.g. following the direction of the tail of an animal.",backward locomotion,biological_process
73843,GO:0043058,"Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.",regulation of backward locomotion,biological_process
73844,GO:0043059,"Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.",regulation of forward locomotion,biological_process
73845,GO:0043060,A cell cycle process whereby homlogous chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator) by the spindle machinery and centromere/kinetochore arrangement during meiosis I chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.,meiotic metaphase I homologous chromosome alignment,biological_process
73846,GO:0043061,"A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiosis II chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.",meiotic metaphase II chromosome alignment,biological_process
73847,GO:0043062,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.",extracellular structure organization,biological_process
73848,GO:0043063,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.",intercellular bridge organization,biological_process
73849,GO:0043065,"Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.",positive regulation of apoptotic process,biological_process
73850,GO:0043066,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.",negative regulation of apoptotic process,biological_process
73851,GO:0043067,"Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.",regulation of programmed cell death,biological_process
73852,GO:0043068,"Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.",positive regulation of programmed cell death,biological_process
73853,GO:0043069,"Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.",negative regulation of programmed cell death,biological_process
73854,GO:0043073,"The nucleus of a germ cell, a reproductive cell in multicellular organisms.",germ cell nucleus,cellular_component
73855,GO:0043076,"The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.",megasporocyte nucleus,cellular_component
73856,GO:0043078,Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus.,polar nucleus,cellular_component
73857,GO:0043079,"The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents.",antipodal cell nucleus,cellular_component
73858,GO:0043082,The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo.,megagametophyte egg cell nucleus,cellular_component
73859,GO:0043083,"The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.",synaptic cleft,cellular_component
73860,GO:0043084,"The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.",penile erection,biological_process
73861,GO:0043085,Any process that activates or increases the activity of an enzyme.,positive regulation of catalytic activity,biological_process
73862,GO:0043086,Any process that stops or reduces the activity of an enzyme.,negative regulation of catalytic activity,biological_process
73863,GO:0043087,Any process that modulates the rate of GTP hydrolysis by a GTPase.,regulation of GTPase activity,biological_process
73864,GO:0043090,The directed movement of amino acids into a cell or organelle.,amino acid import,biological_process
73865,GO:0043093,"A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.",FtsZ-dependent cytokinesis,biological_process
73866,GO:0043094,"Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells.",metabolic compound salvage,biological_process
73867,GO:0043096,"Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.",purine nucleobase salvage,biological_process
73868,GO:0043097,"Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.",pyrimidine nucleoside salvage,biological_process
73869,GO:0043098,"Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.",purine deoxyribonucleoside salvage,biological_process
73870,GO:0043099,"Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis.",pyrimidine deoxyribonucleoside salvage,biological_process
73871,GO:0043100,"Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.",pyrimidine nucleobase salvage,biological_process
73872,GO:0043101,"Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.",purine-containing compound salvage,biological_process
73873,GO:0043102,"Any process which produces an amino acid from derivatives of it, without de novo synthesis.",amino acid salvage,biological_process
73874,GO:0043103,"Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.",hypoxanthine salvage,biological_process
73875,GO:0043107,Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.,type IV pilus-dependent motility,biological_process
73876,GO:0043108,The process of withdrawing a pilus back into a cell.,pilus retraction,biological_process
73877,GO:0043110,"Binding to replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.",rDNA spacer replication fork barrier binding,molecular_function
73878,GO:0043111,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.",replication fork arrest,biological_process
73879,GO:0043112,"The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.",receptor metabolic process,biological_process
73880,GO:0043113,"The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.",receptor clustering,biological_process
73881,GO:0043114,Any process that modulates the extent to which blood vessels can be pervaded by fluid.,regulation of vascular permeability,biological_process
73882,GO:0043115,Catalysis of the reaction: NAD+ + precorrin-2 = 2 H+ + NADH + sirohydrochlorin.,precorrin-2 dehydrogenase activity,molecular_function
73883,GO:0043116,Any process that reduces the extent to which blood vessels can be pervaded by fluid.,negative regulation of vascular permeability,biological_process
73884,GO:0043117,Any process that increases the extent to which blood vessels can be pervaded by fluid.,positive regulation of vascular permeability,biological_process
73885,GO:0043120,"Binding to tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.",tumor necrosis factor binding,molecular_function
73886,GO:0043121,"Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.",neurotrophin binding,molecular_function
73887,GO:0043122,Any process that modulates the canonical NF-kappaB signaling cascade.,regulation of canonical NF-kappaB signal transduction,biological_process
73888,GO:0043123,"Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade.",positive regulation of canonical NF-kappaB signal transduction,biological_process
73889,GO:0043124,"Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade.",negative regulation of canonical NF-kappaB signal transduction,biological_process
73890,GO:0043125,Binding to the protein-tyrosine kinase receptor ErbB-3/HER3.,ErbB-3 class receptor binding,molecular_function
73891,GO:0043129,Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid.,surfactant homeostasis,biological_process
73892,GO:0043130,"Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.",ubiquitin binding,molecular_function
73893,GO:0043131,The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.,erythrocyte enucleation,biological_process
73894,GO:0043132,"The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.",NAD transport,biological_process
73895,GO:0043133,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.",hindgut contraction,biological_process
73896,GO:0043134,"Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.",regulation of hindgut contraction,biological_process
73897,GO:0043135,"Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.",5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity,molecular_function
73898,GO:0043136,Catalysis of the reaction: H2O + sn-glycerol 3-phosphate = glycerol + phosphate.,sn-glycerol 3-phosphatase activity,molecular_function
73899,GO:0043137,"Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.","DNA replication, removal of RNA primer",biological_process
73900,GO:0043138,"Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.",3'-5' DNA helicase activity,molecular_function
73901,GO:0043139,"Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.",5'-3' DNA helicase activity,molecular_function
73902,GO:0043143,"Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.",regulation of translation by machinery localization,biological_process
73903,GO:0043144,Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea).,sno(s)RNA processing,biological_process
73904,GO:0043145,"The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.",sno(s)RNA 3'-end cleavage,biological_process
73905,GO:0043149,"The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.",stress fiber assembly,biological_process
73906,GO:0043150,The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.,DNA synthesis involved in double-strand break repair via homologous recombination,biological_process
73907,GO:0043152,Any process in which infecting bacteria are clumped together by a host organism.,induction of bacterial agglutination,biological_process
73908,GO:0043153,"The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).",entrainment of circadian clock by photoperiod,biological_process
73909,GO:0043155,"Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.","negative regulation of photosynthesis, light reaction",biological_process
73910,GO:0043157,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.",response to cation stress,biological_process
73911,GO:0043158,"The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria.",heterocyst development,biological_process
73912,GO:0043159,"A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.",acrosomal matrix,cellular_component
73913,GO:0043160,The volume enclosed within the acrosome membrane.,acrosomal lumen,cellular_component
73914,GO:0043161,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",proteasome-mediated ubiquitin-dependent protein catabolic process,biological_process
73915,GO:0043162,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.",ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,biological_process
73916,GO:0043163,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.",cell envelope organization,biological_process
73917,GO:0043164,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.",Gram-negative-bacterium-type cell wall biogenesis,biological_process
73918,GO:0043165,"The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.",Gram-negative-bacterium-type cell outer membrane assembly,biological_process
73919,GO:0043167,"Binding to an ion, a charged atoms or groups of atoms.",ion binding,molecular_function
73920,GO:0043168,"Binding to an anion, a charged atom or group of atoms with a net negative charge.",anion binding,molecular_function
73921,GO:0043169,"Binding to a cation, a charged atom or group of atoms with a net positive charge.",cation binding,molecular_function
73922,GO:0043170,"The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",macromolecule metabolic process,biological_process
73923,GO:0043171,"The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.",peptide catabolic process,biological_process
73924,GO:0043173,"Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.",nucleotide salvage,biological_process
73925,GO:0043174,"Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.",nucleoside salvage,biological_process
73926,GO:0043175,"Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.",RNA polymerase core enzyme binding,molecular_function
73927,GO:0043176,"Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.",amine binding,molecular_function
73928,GO:0043177,"Binding to an organic acid, any acidic compound containing carbon in covalent linkage.",organic acid binding,molecular_function
73929,GO:0043178,"Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.",alcohol binding,molecular_function
73930,GO:0043179,"Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.",rhythmic excitation,biological_process
73931,GO:0043180,"Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.",rhythmic inhibition,biological_process
73932,GO:0043183,Binding to a vascular endothelial growth factor receptor 1.,vascular endothelial growth factor receptor 1 binding,molecular_function
73933,GO:0043184,Binding to a vascular endothelial growth factor receptor 2.,vascular endothelial growth factor receptor 2 binding,molecular_function
73934,GO:0043185,Binding to a vascular endothelial growth factor receptor 3.,vascular endothelial growth factor receptor 3 binding,molecular_function
73935,GO:0043186,"A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.",P granule,cellular_component
73936,GO:0043188,The cell wall material that surrounds the septum in fungal cells.,cell septum edging,cellular_component
73937,GO:0043189,A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.,H4/H2A histone acetyltransferase complex,cellular_component
73938,GO:0043190,"A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate b...",ATP-binding cassette (ABC) transporter complex,cellular_component
73939,GO:0043194,"Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.",axon initial segment,cellular_component
73940,GO:0043195,"Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.",terminal bouton,cellular_component
73941,GO:0043196,"Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.",varicosity,cellular_component
73942,GO:0043197,"A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.",dendritic spine,cellular_component
73943,GO:0043198,"Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.",dendritic shaft,cellular_component
73944,GO:0043199,"Binding to sulfate, SO4(2-), a negatively charged small molecule.",sulfate binding,molecular_function
73945,GO:0043200,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.",response to amino acid,biological_process
73946,GO:0043201,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus.",response to L-leucine,biological_process
73947,GO:0043202,The volume enclosed within the lysosomal membrane.,lysosomal lumen,cellular_component
73948,GO:0043203,Portion of the neuronal cell soma from which the axon originates.,axon hillock,cellular_component
73949,GO:0043204,The portion of the cell soma (neuronal cell body) that excludes the nucleus.,perikaryon,cellular_component
73950,GO:0043207,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.",response to external biotic stimulus,biological_process
73951,GO:0043208,"Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.",glycosphingolipid binding,molecular_function
73952,GO:0043209,An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.,myelin sheath,cellular_component
73953,GO:0043210,"Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.",alkanesulfonate binding,molecular_function
73954,GO:0043211,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates and their derivatives across a membrane.",ABC-type carbohydrate transporter activity,molecular_function
73955,GO:0043213,"The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.",bacteriocin transport,biological_process
73956,GO:0043214,Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate.,ABC-type bacteriocin transporter activity,molecular_function
73957,GO:0043215,"The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",daunorubicin transport,biological_process
73958,GO:0043217,"The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.",myelin maintenance,biological_process
73959,GO:0043218,"The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.",compact myelin,cellular_component
73960,GO:0043219,"Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.",lateral loop,cellular_component
73961,GO:0043220,"Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.",Schmidt-Lanterman incisure,cellular_component
73962,GO:0043221,"Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.",SMC family protein binding,molecular_function
73963,GO:0043223,"A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).",cytoplasmic SCF ubiquitin ligase complex,cellular_component
73964,GO:0043224,"A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).",nuclear SCF ubiquitin ligase complex,cellular_component
73965,GO:0043226,"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.",organelle,cellular_component
73966,GO:0043227,"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",membrane-bounded organelle,cellular_component
73967,GO:0043228,"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.",membraneless organelle,cellular_component
73968,GO:0043229,"Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",intracellular organelle,cellular_component
73969,GO:0043230,"Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.",extracellular organelle,cellular_component
73970,GO:0043231,"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",intracellular membrane-bounded organelle,cellular_component
73971,GO:0043232,"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.",intracellular membraneless organelle,cellular_component
73972,GO:0043233,"The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.",organelle lumen,cellular_component
73973,GO:0043235,"Any protein complex that binds a signaling molecule such as a hormone, neurotransmitter, molecular pattern recognition receptor (PAMPs and DAMPS), or an intracellular messenger to initiate a change in cell function.",signaling receptor complex,cellular_component
73974,GO:0043236,"Binding to a laminin, a major glycoprotein constituent of the basement membrane of cells.",laminin binding,molecular_function
73975,GO:0043237,"Binding to laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.",laminin-1 binding,molecular_function
73976,GO:0043240,"A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.",Fanconi anaemia nuclear complex,cellular_component
73977,GO:0043242,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.",negative regulation of protein-containing complex disassembly,biological_process
73978,GO:0043243,"Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.",positive regulation of protein-containing complex disassembly,biological_process
73979,GO:0043244,"Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.",regulation of protein-containing complex disassembly,biological_process
73980,GO:0043245,The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms.,extraorganismal space,cellular_component
73981,GO:0043246,"Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.",megasome,cellular_component
73982,GO:0043247,Any process that occur in response to the presence of critically short or damaged telomeres.,telomere maintenance in response to DNA damage,biological_process
73983,GO:0043248,"The aggregation, arrangement and bonding together of a mature, active proteasome complex.",proteasome assembly,biological_process
73984,GO:0043249,"A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.",erythrocyte maturation,biological_process
73985,GO:0043251,"The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sodium-dependent organic anion transport,biological_process
73986,GO:0043252,"The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sodium-independent organic anion transport,biological_process
73987,GO:0043253,A ribosome contained within a chloroplast.,chloroplast ribosome,cellular_component
73988,GO:0043254,"Any process that modulates the frequency, rate or extent of protein complex assembly.",regulation of protein-containing complex assembly,biological_process
73989,GO:0043255,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.",regulation of carbohydrate biosynthetic process,biological_process
73990,GO:0043256,"A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.",laminin trimer,cellular_component
73991,GO:0043257,"A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.",laminin-411 trimer,cellular_component
73992,GO:0043258,"A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.",laminin-421 trimer,cellular_component
73993,GO:0043259,"A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.",laminin-511 trimer,cellular_component
73994,GO:0043260,"A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.",laminin-521 trimer,cellular_component
73995,GO:0043261,"A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.",laminin-213 trimer,cellular_component
73996,GO:0043262,Catalysis of the reaction: ADP + H2O = AMP + phosphate + H+.,ADP phosphatase activity,molecular_function
73997,GO:0043263,An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose.,cellulosome,cellular_component
73998,GO:0043264,"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.",extracellular membraneless organelle,cellular_component
73999,GO:0043266,"Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of potassium ion transport,biological_process
74000,GO:0043267,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of potassium ion transport,biological_process
74001,GO:0043268,"Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of potassium ion transport,biological_process
74002,GO:0043269,"Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of monoatomic ion transport,biological_process
74003,GO:0043270,"Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of monoatomic ion transport,biological_process
74004,GO:0043271,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of monoatomic ion transport,biological_process
74005,GO:0043273,Catalysis of the reaction: CTP + H2O = CDP + H+ + phosphate. May or may not be coupled to another reaction.,CTPase activity,molecular_function
74006,GO:0043274,Binding to a phospholipase.,phospholipase binding,molecular_function
74007,GO:0043276,Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.,anoikis,biological_process
74008,GO:0043277,The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.,apoptotic cell clearance,biological_process
74009,GO:0043278,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.",response to morphine,biological_process
74010,GO:0043279,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.",response to alkaloid,biological_process
74011,GO:0043282,"The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.",chordate pharyngeal muscle development,biological_process
74012,GO:0043286,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.",regulation of poly(3-hydroxyalkanoate) biosynthetic process,biological_process
74013,GO:0043287,"Binding to a poly(3-hydroxyalkanoate), a polyester of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.",poly(3-hydroxyalkanoate) binding,molecular_function
74014,GO:0043289,The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.,apocarotenoid biosynthetic process,biological_process
74015,GO:0043290,"The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.",apocarotenoid catabolic process,biological_process
74016,GO:0043291,"A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.",RAVE complex,cellular_component
74017,GO:0043292,"Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.",contractile muscle fiber,cellular_component
74018,GO:0043293,A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.,apoptosome,cellular_component
74019,GO:0043294,"A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.",mitochondrial glutamate synthase complex (NADH),cellular_component
74020,GO:0043295,"Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.",glutathione binding,molecular_function
74021,GO:0043296,"A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.",apical junction complex,cellular_component
74022,GO:0043297,"The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.",apical junction assembly,biological_process
74023,GO:0043299,The regulated exocytosis of secretory granules by a leukocyte.,leukocyte degranulation,biological_process
74024,GO:0043300,"Any process that modulates the frequency, rate, or extent of leukocyte degranulation.",regulation of leukocyte degranulation,biological_process
74025,GO:0043301,"Any process that stops, prevents, or reduces the rate of leukocyte degranulation.",negative regulation of leukocyte degranulation,biological_process
74026,GO:0043302,"Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.",positive regulation of leukocyte degranulation,biological_process
74027,GO:0043303,"The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.",mast cell degranulation,biological_process
74028,GO:0043304,"Any process that modulates the frequency, rate, or extent of mast cell degranulation.",regulation of mast cell degranulation,biological_process
74029,GO:0043305,"Any process that stops, prevents, or reduces the rate of mast cell degranulation.",negative regulation of mast cell degranulation,biological_process
74030,GO:0043306,"Any process that activates or increases the frequency, rate or extent of mast cell degranulation.",positive regulation of mast cell degranulation,biological_process
74031,GO:0043307,"The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",eosinophil activation,biological_process
74032,GO:0043308,"The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.",eosinophil degranulation,biological_process
74033,GO:0043309,"Any process that modulates the frequency, rate, or extent of eosinophil degranulation.",regulation of eosinophil degranulation,biological_process
74034,GO:0043310,"Any process that stops, prevents, or reduces the rate of eosinophil degranulation.",negative regulation of eosinophil degranulation,biological_process
74035,GO:0043311,"Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.",positive regulation of eosinophil degranulation,biological_process
74036,GO:0043312,"The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.",neutrophil degranulation,biological_process
74037,GO:0043313,"Any process that modulates the frequency, rate, or extent of neutrophil degranulation.",regulation of neutrophil degranulation,biological_process
74038,GO:0043314,"Any process that stops, prevents, or reduces the rate of neutrophil degranulation.",negative regulation of neutrophil degranulation,biological_process
74039,GO:0043315,"Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.",positive regulation of neutrophil degranulation,biological_process
74040,GO:0043316,The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.,cytotoxic T cell degranulation,biological_process
74041,GO:0043317,"Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.",regulation of cytotoxic T cell degranulation,biological_process
74042,GO:0043318,"Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation.",negative regulation of cytotoxic T cell degranulation,biological_process
74043,GO:0043319,"Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.",positive regulation of cytotoxic T cell degranulation,biological_process
74044,GO:0043320,The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.,natural killer cell degranulation,biological_process
74045,GO:0043321,"Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.",regulation of natural killer cell degranulation,biological_process
74046,GO:0043322,"Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.",negative regulation of natural killer cell degranulation,biological_process
74047,GO:0043323,"Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.",positive regulation of natural killer cell degranulation,biological_process
74048,GO:0043324,"The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.",pigment metabolic process involved in developmental pigmentation,biological_process
74049,GO:0043325,"Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.","phosphatidylinositol-3,4-bisphosphate binding",molecular_function
74050,GO:0043326,The directed movement of a motile cell or organism in response to the presence of folate.,chemotaxis to folate,biological_process
74051,GO:0043327,"The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.",chemotaxis to cAMP,biological_process
74052,GO:0043328,The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.,protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,biological_process
74053,GO:0043330,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.",response to exogenous dsRNA,biological_process
74054,GO:0043331,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.",response to dsRNA,biological_process
74055,GO:0043332,The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.,mating projection tip,cellular_component
74056,GO:0043335,"The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.",protein unfolding,biological_process
74057,GO:0043336,Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.,site-specific telomere resolvase activity,molecular_function
74058,GO:0043337,"Catalysis of the reaction: a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H+.",cardiolipin synthase (CMP-forming) activity,molecular_function
74059,GO:0043338,"Catalysis of the reaction: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H+ = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate.","CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase activity",molecular_function
74060,GO:0043353,The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.,enucleate erythrocyte differentiation,biological_process
74061,GO:0043354,"A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.",enucleate erythrocyte maturation,biological_process
74062,GO:0043362,"A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.",nucleate erythrocyte maturation,biological_process
74063,GO:0043363,"The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.",nucleate erythrocyte differentiation,biological_process
74064,GO:0043364,Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).,glycyl-radical enzyme activating activity,molecular_function
74065,GO:0043365,Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.,[formate-C-acetyltransferase]-activating enzyme activity,molecular_function
74066,GO:0043366,The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.,beta selection,biological_process
74067,GO:0043367,"The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.","CD4-positive, alpha-beta T cell differentiation",biological_process
74068,GO:0043368,The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.,positive T cell selection,biological_process
74069,GO:0043369,The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.,"CD4-positive or CD8-positive, alpha-beta T cell lineage commitment",biological_process
74070,GO:0043370,"Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.","regulation of CD4-positive, alpha-beta T cell differentiation",biological_process
74071,GO:0043371,"Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.","negative regulation of CD4-positive, alpha-beta T cell differentiation",biological_process
74072,GO:0043372,"Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.","positive regulation of CD4-positive, alpha-beta T cell differentiation",biological_process
74073,GO:0043373,"The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.","CD4-positive, alpha-beta T cell lineage commitment",biological_process
74074,GO:0043374,"The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.","CD8-positive, alpha-beta T cell differentiation",biological_process
74075,GO:0043375,"The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.","CD8-positive, alpha-beta T cell lineage commitment",biological_process
74076,GO:0043376,"Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.","regulation of CD8-positive, alpha-beta T cell differentiation",biological_process
74077,GO:0043377,"Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.","negative regulation of CD8-positive, alpha-beta T cell differentiation",biological_process
74078,GO:0043378,"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.","positive regulation of CD8-positive, alpha-beta T cell differentiation",biological_process
74079,GO:0043379,The process in which a newly activated T cell acquires specialized features of a memory T cell.,memory T cell differentiation,biological_process
74080,GO:0043380,"Any process that modulates the frequency, rate, or extent of memory T cell differentiation.",regulation of memory T cell differentiation,biological_process
74081,GO:0043381,"Any process that stops, prevents, or reduces the rate of memory T cell differentiation.",negative regulation of memory T cell differentiation,biological_process
74082,GO:0043382,"Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.",positive regulation of memory T cell differentiation,biological_process
74083,GO:0043383,The process of elimination of immature T cells which react strongly with self-antigens.,negative T cell selection,biological_process
74084,GO:0043384,"A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.",pre-T cell receptor complex,cellular_component
74085,GO:0043385,"The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.",mycotoxin metabolic process,biological_process
74086,GO:0043386,"The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.",mycotoxin biosynthetic process,biological_process
74087,GO:0043387,"The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.",mycotoxin catabolic process,biological_process
74088,GO:0043388,"Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).",positive regulation of DNA binding,biological_process
74089,GO:0043392,"Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).",negative regulation of DNA binding,biological_process
74090,GO:0043393,"Any process that modulates the frequency, rate or extent of protein binding.",regulation of protein binding,biological_process
74091,GO:0043394,"Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",proteoglycan binding,molecular_function
74092,GO:0043395,"Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.",heparan sulfate proteoglycan binding,molecular_function
74093,GO:0043396,"The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.",corticotropin-releasing hormone secretion,biological_process
74094,GO:0043397,"Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.",regulation of corticotropin-releasing hormone secretion,biological_process
74095,GO:0043398,"Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.",HLH domain binding,molecular_function
74096,GO:0043399,Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.,tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity,molecular_function
74097,GO:0043400,"The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.",cortisol secretion,biological_process
74098,GO:0043401,The series of molecular signals mediated by a steroid hormone binding to a receptor.,steroid hormone receptor signaling pathway,biological_process
74099,GO:0043403,The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.,skeletal muscle tissue regeneration,biological_process
74100,GO:0043404,Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.,corticotropin-releasing hormone receptor activity,molecular_function
74101,GO:0043405,"Any process that modulates the frequency, rate or extent of MAP kinase activity.",regulation of MAP kinase activity,biological_process
74102,GO:0043406,"Any process that activates or increases the frequency, rate or extent of MAP kinase activity.",positive regulation of MAP kinase activity,biological_process
74103,GO:0043407,"Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.",negative regulation of MAP kinase activity,biological_process
74104,GO:0043408,"Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.",regulation of MAPK cascade,biological_process
74105,GO:0043409,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.",negative regulation of MAPK cascade,biological_process
74106,GO:0043410,"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.",positive regulation of MAPK cascade,biological_process
74107,GO:0043412,"The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.",macromolecule modification,biological_process
74108,GO:0043414,"The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.",macromolecule methylation,biological_process
74109,GO:0043415,Any process that activates or increase the rate of skeletal muscle regeneration.,positive regulation of skeletal muscle tissue regeneration,biological_process
74110,GO:0043416,"Any process that modulates the frequency, rate or extent of skeletal muscle.",regulation of skeletal muscle tissue regeneration,biological_process
74111,GO:0043417,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.",negative regulation of skeletal muscle tissue regeneration,biological_process
74112,GO:0043418,"The chemical reactions and pathways resulting in the breakdown of L-homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.",L-homocysteine catabolic process,biological_process
74113,GO:0043419,"The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.",urea catabolic process,biological_process
74114,GO:0043421,The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).,anthranilate catabolic process,biological_process
74115,GO:0043422,"Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.",protein kinase B binding,molecular_function
74116,GO:0043423,Binding to a 3-phosphoinositide-dependent protein kinase.,3-phosphoinositide-dependent protein kinase binding,molecular_function
74117,GO:0043424,Binding to a protein histidine kinase.,protein histidine kinase binding,molecular_function
74118,GO:0043425,"Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.",bHLH transcription factor binding,molecular_function
74119,GO:0043426,"Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.",MRF binding,molecular_function
74120,GO:0043427,"An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.",carbon fixation by 3-hydroxypropionate cycle,biological_process
74121,GO:0043434,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.",response to peptide hormone,biological_process
74122,GO:0043435,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.",response to corticotropin-releasing hormone,biological_process
74123,GO:0043436,"The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).",oxoacid metabolic process,biological_process
74124,GO:0043447,"The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.",alkane biosynthetic process,biological_process
74125,GO:0043448,"The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.",alkane catabolic process,biological_process
74126,GO:0043450,"The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.",alkene biosynthetic process,biological_process
74127,GO:0043451,"The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.",alkene catabolic process,biological_process
74128,GO:0043453,"The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.",alkyne biosynthetic process,biological_process
74129,GO:0043454,"The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.",alkyne catabolic process,biological_process
74130,GO:0043455,"Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.",regulation of secondary metabolic process,biological_process
74131,GO:0043456,"Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.",regulation of pentose-phosphate shunt,biological_process
74132,GO:0043457,"Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.",regulation of cellular respiration,biological_process
74133,GO:0043461,"The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.",proton-transporting ATP synthase complex assembly,biological_process
74134,GO:0043462,Any process that modulates the rate of an ATP-dependent activity.,regulation of ATP-dependent activity,biological_process
74135,GO:0043463,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.",regulation of rhamnose catabolic process,biological_process
74136,GO:0043464,The chemical reactions and pathways resulting in the breakdown of L-malate.,L-malate catabolic process,biological_process
74137,GO:0043465,"Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).",regulation of fermentation,biological_process
74138,GO:0043467,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.",regulation of generation of precursor metabolites and energy,biological_process
74139,GO:0043468,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of L-fucose.",regulation of L-fucose catabolic process,biological_process
74140,GO:0043469,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.",regulation of D-xylose catabolic process,biological_process
74141,GO:0043470,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.",regulation of carbohydrate catabolic process,biological_process
74142,GO:0043472,Binding to an immunoglobulin of a D isotype.,IgD binding,molecular_function
74143,GO:0043473,"The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.",pigmentation,biological_process
74144,GO:0043474,"The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.",pigment metabolic process involved in pigmentation,biological_process
74145,GO:0043476,"The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.",pigment accumulation,biological_process
74146,GO:0043477,"The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.",pigment biosynthetic process involved in pigment accumulation,biological_process
74147,GO:0043478,"The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.",pigment accumulation in response to UV light,biological_process
74148,GO:0043479,"The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.",pigment accumulation in tissues in response to UV light,biological_process
74149,GO:0043480,"The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.",pigment accumulation in tissues,biological_process
74150,GO:0043481,"The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.",anthocyanin accumulation in tissues in response to UV light,biological_process
74151,GO:0043482,"The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.",cellular pigment accumulation,biological_process
74152,GO:0043484,"Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.",regulation of RNA splicing,biological_process
74153,GO:0043485,The directed movement of substances from endosomes to pigment granules.,endosome to pigment granule transport,biological_process
74154,GO:0043487,Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.,regulation of RNA stability,biological_process
74155,GO:0043488,Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.,regulation of mRNA stability,biological_process
74156,GO:0043489,Prevention of degradation of RNA molecules.,RNA stabilization,biological_process
74157,GO:0043490,"The process of transferring reducing equivalents from NADH in the cytosol to the mitochondria via malate. Cytosolic aspartate aminotransferase converts aspartate to oxaloacetate, and cytosolic malate dehydrogenase uses NADH to convert oxaloacetate to malate in the cytosol; the malate-alpha-ketoglutarate carrier then transports the malate into the mitochondria where mitochondrial malate dehydrogenase uses NAD to convert malate back to oxaloacetate; the electrons on the reduced NADH are then av...",malate-aspartate shuttle,biological_process
74158,GO:0043491,"An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.",phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process
74159,GO:0043493,"A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.",viral terminase complex,cellular_component
74160,GO:0043494,An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.,CLRC complex,cellular_component
74161,GO:0043495,"The binding activity of a molecule that brings together a protein or a protein complex with a membrane, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.",protein-membrane adaptor activity,molecular_function
74162,GO:0043500,"A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.",muscle adaptation,biological_process
74163,GO:0043501,Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.,skeletal muscle adaptation,biological_process
74164,GO:0043502,"Any process that modulates the frequency, rate or extent of muscle adaptation.",regulation of muscle adaptation,biological_process
74165,GO:0043503,"Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.",skeletal muscle fiber adaptation,biological_process
74166,GO:0043504,The process of restoring mitochondrial DNA after damage.,mitochondrial DNA repair,biological_process
74167,GO:0043505,"A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).",CENP-A containing nucleosome,cellular_component
74168,GO:0043506,"Any process that modulates the frequency, rate or extent of JUN kinase activity.",regulation of JUN kinase activity,biological_process
74169,GO:0043507,"Any process that activates or increases the frequency, rate or extent of JUN kinase activity.",positive regulation of JUN kinase activity,biological_process
74170,GO:0043508,"Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.",negative regulation of JUN kinase activity,biological_process
74171,GO:0043509,"A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).",activin A complex,cellular_component
74172,GO:0043510,"A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B).",activin B complex,cellular_component
74173,GO:0043511,"Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B.",inhibin complex,cellular_component
74174,GO:0043512,Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.,inhibin A complex,cellular_component
74175,GO:0043513,Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.,inhibin B complex,cellular_component
74176,GO:0043514,"A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.",interleukin-12 complex,cellular_component
74177,GO:0043515,"Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.",kinetochore binding,molecular_function
74178,GO:0043516,"Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.","regulation of DNA damage response, signal transduction by p53 class mediator",biological_process
74179,GO:0043517,"Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.","positive regulation of DNA damage response, signal transduction by p53 class mediator",biological_process
74180,GO:0043518,"Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.","negative regulation of DNA damage response, signal transduction by p53 class mediator",biological_process
74181,GO:0043519,"Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.",regulation of myosin II filament organization,biological_process
74182,GO:0043520,"Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.",regulation of myosin II filament assembly,biological_process
74183,GO:0043521,"Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.",regulation of myosin II filament disassembly,biological_process
74184,GO:0043522,"Binding to a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.",leucine zipper domain binding,molecular_function
74185,GO:0043523,Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.,regulation of neuron apoptotic process,biological_process
74186,GO:0043524,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.",negative regulation of neuron apoptotic process,biological_process
74187,GO:0043525,"Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.",positive regulation of neuron apoptotic process,biological_process
74188,GO:0043527,A multimeric protein complex involved in the methylation of specific nucleotides in tRNA.,tRNA methyltransferase complex,cellular_component
74189,GO:0043528,"A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.",tRNA (m2G10) methyltransferase complex,cellular_component
74190,GO:0043529,"An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins.",GET complex,cellular_component
74191,GO:0043530,"Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.",adenosine 5'-monophosphoramidase activity,molecular_function
74192,GO:0043531,"Binding to ADP, adenosine 5'-diphosphate.",ADP binding,molecular_function
74193,GO:0043532,"Binding to angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.",angiostatin binding,molecular_function
74194,GO:0043533,"Binding to inositol 1,3,4,5 tetrakisphosphate.","inositol 1,3,4,5 tetrakisphosphate binding",molecular_function
74195,GO:0043534,The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.,blood vessel endothelial cell migration,biological_process
74196,GO:0043535,"Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.",regulation of blood vessel endothelial cell migration,biological_process
74197,GO:0043536,"Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.",positive regulation of blood vessel endothelial cell migration,biological_process
74198,GO:0043537,"Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.",negative regulation of blood vessel endothelial cell migration,biological_process
74199,GO:0043539,Binds to and increases the activity of a protein serine/threonine kinase.,protein serine/threonine kinase activator activity,molecular_function
74200,GO:0043540,"A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex",cellular_component
74201,GO:0043541,"A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis.",UDP-N-acetylglucosamine transferase complex,cellular_component
74202,GO:0043542,The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.,endothelial cell migration,biological_process
74203,GO:0043543,"The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.",protein acylation,biological_process
74204,GO:0043544,"Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.",lipoamide binding,molecular_function
74205,GO:0043545,"The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.",molybdopterin cofactor metabolic process,biological_process
74206,GO:0043546,"Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.",molybdopterin cofactor binding,molecular_function
74207,GO:0043547,Any process that activates or increases the activity of a GTPase.,positive regulation of GTPase activity,biological_process
74208,GO:0043548,"Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.",phosphatidylinositol 3-kinase binding,molecular_function
74209,GO:0043549,"Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.",regulation of kinase activity,biological_process
74210,GO:0043550,"Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.",regulation of lipid kinase activity,biological_process
74211,GO:0043554,"The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems.","aerobic respiration, using arsenite as electron donor",biological_process
74212,GO:0043555,"Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",regulation of translation in response to stress,biological_process
74213,GO:0043556,"Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.",regulation of translation in response to oxidative stress,biological_process
74214,GO:0043557,"Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",regulation of translation in response to osmotic stress,biological_process
74215,GO:0043558,"Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.",regulation of translational initiation in response to stress,biological_process
74216,GO:0043559,"Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.",insulin binding,molecular_function
74217,GO:0043560,"Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.",insulin receptor substrate binding,molecular_function
74218,GO:0043561,"Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",regulation of translational initiation in response to osmotic stress,biological_process
74219,GO:0043562,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.",cellular response to nitrogen levels,biological_process
74220,GO:0043564,"Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.",Ku70:Ku80 complex,cellular_component
74221,GO:0043565,"Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",sequence-specific DNA binding,molecular_function
74222,GO:0043567,"Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.",regulation of insulin-like growth factor receptor signaling pathway,biological_process
74223,GO:0043568,"Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.",positive regulation of insulin-like growth factor receptor signaling pathway,biological_process
74224,GO:0043569,"Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.",negative regulation of insulin-like growth factor receptor signaling pathway,biological_process
74225,GO:0043570,Any process involved in sustaining the fidelity and copy number of DNA repeat elements.,maintenance of DNA repeat elements,biological_process
74226,GO:0043571,"Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a fam...",maintenance of CRISPR repeat elements,biological_process
74227,GO:0043572,"The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.",plastid fission,biological_process
74228,GO:0043573,The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.,leucoplast fission,biological_process
74229,GO:0043574,"Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.",peroxisomal transport,biological_process
74230,GO:0043575,The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.,detection of osmotic stimulus,biological_process
74231,GO:0043576,"Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.",regulation of respiratory gaseous exchange,biological_process
74232,GO:0043577,"The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.",chemotropism,biological_process
74233,GO:0043578,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.",nuclear matrix organization,biological_process
74234,GO:0043579,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.",elaioplast organization,biological_process
74235,GO:0043580,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.",periplasmic space organization,biological_process
74236,GO:0043582,"The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.",sporangium development,biological_process
74237,GO:0043583,"The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.",ear development,biological_process
74238,GO:0043584,"The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).",nose development,biological_process
74239,GO:0043585,The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).,nose morphogenesis,biological_process
74240,GO:0043586,"The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.",tongue development,biological_process
74241,GO:0043587,"The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.",tongue morphogenesis,biological_process
74242,GO:0043588,"The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true s...",skin development,biological_process
74243,GO:0043589,"The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed most...",skin morphogenesis,biological_process
74244,GO:0043590,The region of a bacterial cell to which the DNA is confined.,bacterial nucleoid,cellular_component
74245,GO:0043591,The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.,endospore external encapsulating structure,cellular_component
74246,GO:0043592,"The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.",exosporium,cellular_component
74247,GO:0043593,"The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination.",endospore coat,cellular_component
74248,GO:0043594,"The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.",outer endospore membrane,cellular_component
74249,GO:0043595,"A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.",endospore cortex,cellular_component
74250,GO:0043596,"The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.",nuclear replication fork,cellular_component
74251,GO:0043597,"The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.",cytoplasmic replication fork,cellular_component
74252,GO:0043598,"A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species.",cytoplasmic DNA replication factor C complex,cellular_component
74253,GO:0043599,"A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.",nuclear DNA replication factor C complex,cellular_component
74254,GO:0043600,"A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.",cytoplasmic replisome,cellular_component
74255,GO:0043601,"A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.",nuclear replisome,cellular_component
74256,GO:0043602,"The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.",nitrate catabolic process,biological_process
74257,GO:0043609,"Any process that modulates the frequency, rate, or extent of carbon utilization.",regulation of carbon utilization,biological_process
74258,GO:0043610,"Any process that modulates the frequency, rate or extent of carbohydrate utilization.",regulation of carbohydrate utilization,biological_process
74259,GO:0043613,"The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8.",isoprene catabolic process,biological_process
74260,GO:0043614,"A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.",multi-eIF complex,cellular_component
74261,GO:0043615,"The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.",astrocyte cell migration,biological_process
74262,GO:0043616,"The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.",keratinocyte proliferation,biological_process
74263,GO:0043617,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose.",cellular response to sucrose starvation,biological_process
74264,GO:0043622,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.",cortical microtubule organization,biological_process
74265,GO:0043625,"A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.",delta DNA polymerase complex,cellular_component
74266,GO:0043626,"A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragme...",PCNA complex,cellular_component
74267,GO:0043627,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.",response to estrogen,biological_process
74268,GO:0043628,Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule.,regulatory ncRNA 3'-end processing,biological_process
74269,GO:0043632,"The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.",modification-dependent macromolecule catabolic process,biological_process
74270,GO:0043633,"The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.",polyadenylation-dependent RNA catabolic process,biological_process
74271,GO:0043634,"The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.",polyadenylation-dependent ncRNA catabolic process,biological_process
74272,GO:0043635,"The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.",methylnaphthalene catabolic process,biological_process
74273,GO:0043636,"The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.",bisphenol A catabolic process,biological_process
74274,GO:0043638,"The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.",puromycin biosynthetic process,biological_process
74275,GO:0043639,"The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.",benzoate catabolic process,biological_process
74276,GO:0043642,"The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.",novobiocin biosynthetic process,biological_process
74277,GO:0043644,"The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).",tetracycline biosynthetic process,biological_process
74278,GO:0043646,"The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.",cephalosporin biosynthetic process,biological_process
74279,GO:0043647,"The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",inositol phosphate metabolic process,biological_process
74280,GO:0043648,"The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).",dicarboxylic acid metabolic process,biological_process
74281,GO:0043649,"The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.",dicarboxylic acid catabolic process,biological_process
74282,GO:0043650,"The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.",dicarboxylic acid biosynthetic process,biological_process
74283,GO:0043651,"The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.",linoleic acid metabolic process,biological_process
74284,GO:0043652,"The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.",engulfment of apoptotic cell,biological_process
74285,GO:0043653,The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.,mitochondrial fragmentation involved in apoptotic process,biological_process
74286,GO:0043654,The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.,recognition of apoptotic cell,biological_process
74287,GO:0043655,"The space within a host but external to the plasma membrane of host cells, e.g. host bloodstream.",host extracellular region,cellular_component
74288,GO:0043656,That space within the plasma membrane of a host cell.,host intracellular region,cellular_component
74289,GO:0043657,A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.,host cell,cellular_component
74290,GO:0043658,"A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.",host symbiosome,cellular_component
74291,GO:0043659,"A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane).",symbiosome,cellular_component
74292,GO:0043660,"A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants.",bacteroid-containing symbiosome,cellular_component
74293,GO:0043661,A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).,peribacteroid membrane,cellular_component
74294,GO:0043662,"The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome.",peribacteroid fluid,cellular_component
74295,GO:0043663,"A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.",host bacteroid-containing symbiosome,cellular_component
74296,GO:0043664,A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).,host peribacteroid membrane,cellular_component
74297,GO:0043665,"The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell.",host peribacteroid fluid,cellular_component
74298,GO:0043667,"The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.",pollen wall,cellular_component
74299,GO:0043668,The outer layer of the pollen grain wall which is composed primarily of sporopollenin.,exine,cellular_component
74300,GO:0043669,"The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections.",ectexine,cellular_component
74301,GO:0043670,The inner layer of the ectexine.,foot layer,cellular_component
74302,GO:0043671,"The inner part of the exine, which stains.",endexine,cellular_component
74303,GO:0043672,"The inner, non-sculptured part of the exine which lies below the sexine.",nexine,cellular_component
74304,GO:0043673,"The outer, sculptured layer of the exine, which lies above the nexine.",sexine,cellular_component
74305,GO:0043674,"A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella).",columella,cellular_component
74306,GO:0043675,The third layer of the sexine.,sculpture element,cellular_component
74307,GO:0043676,"The layer of sexine which forms a roof over the columella, granules or other infratectal elements.",tectum,cellular_component
74308,GO:0043678,The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm.,intine,cellular_component
74309,GO:0043679,"Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.",axon terminus,cellular_component
74310,GO:0043680,"A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells.",filiform apparatus,cellular_component
74311,GO:0043682,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) = ADP + phosphate + Cu2+(out).,P-type divalent copper transporter activity,molecular_function
74312,GO:0043683,The assembly from its constituent parts of a type IV pilus.,type IV pilus assembly,biological_process
74313,GO:0043684,"A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s).",type IV secretion system complex,cellular_component
74314,GO:0043685,The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.,conversion of glutamyl-tRNA to glutaminyl-tRNA,biological_process
74315,GO:0043687,The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.,post-translational protein modification,biological_process
74316,GO:0043688,The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA.,conversion of aspartyl-tRNA to asparaginyl-tRNA,biological_process
74317,GO:0043691,"The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism.",reverse cholesterol transport,biological_process
74318,GO:0043692,"The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.",monoterpene metabolic process,biological_process
74319,GO:0043693,"The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.",monoterpene biosynthetic process,biological_process
74320,GO:0043694,"The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.",monoterpene catabolic process,biological_process
74321,GO:0043695,The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.,detection of pheromone,biological_process
74322,GO:0043696,"The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.",dedifferentiation,biological_process
74323,GO:0043697,"The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.",cell dedifferentiation,biological_process
74324,GO:0043698,"A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance.",iridosome,cellular_component
74325,GO:0043699,"A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast.",leucosome,cellular_component
74326,GO:0043700,"A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.",pterinosome,cellular_component
74327,GO:0043701,"A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance.",cyanosome,cellular_component
74328,GO:0043702,"A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.",carotenoid vesicle,cellular_component
74329,GO:0043703,"The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.",photoreceptor cell fate determination,biological_process
74330,GO:0043704,"The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",photoreceptor cell fate specification,biological_process
74331,GO:0043707,"The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.",cell adhesion involved in single-species biofilm formation in or on host organism,biological_process
74332,GO:0043708,"The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.",cell adhesion involved in biofilm formation,biological_process
74333,GO:0043709,"The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.",cell adhesion involved in single-species biofilm formation,biological_process
74334,GO:0043710,"The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.",cell adhesion involved in multi-species biofilm formation,biological_process
74335,GO:0043711,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.",pilus organization,biological_process
74336,GO:0043712,Catalysis of the reaction: 4-methylpentanoyl-CoA + (2R)-hydroxy-4-methylpentanoate = (R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate.,(R)-2-hydroxy-4-methylpentanoate CoA-transferase activity,molecular_function
74337,GO:0043714,Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA.,(R)-citramalate synthase activity,molecular_function
74338,GO:0043715,"Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.","2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity",molecular_function
74339,GO:0043716,"Catalysis of the reaction: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate.",2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity,molecular_function
74340,GO:0043717,Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.,2-hydroxyglutaryl-CoA dehydratase activity,molecular_function
74341,GO:0043718,Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD+ = 2-formylglutarate + H+ + NADH.,2-hydroxymethylglutarate dehydrogenase activity,molecular_function
74342,GO:0043720,Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.,3-keto-5-aminohexanoate cleavage activity,molecular_function
74343,GO:0043721,Catalysis of the reaction: 4-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O.,4-hydroxybutanoyl-CoA dehydratase activity,molecular_function
74344,GO:0043722,Catalysis of the reaction: (4-hydroxyphenyl)acetate + H+ = 4-cresol + CO2.,4-hydroxyphenylacetate decarboxylase activity,molecular_function
74345,GO:0043724,Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.,2-keto-3-deoxygalactonate aldolase activity,molecular_function
74346,GO:0043726,Catalysis of the reaction: 5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O = 5-amino-6-(D-ribitylamino)uracil + phosphate.,5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity,molecular_function
74347,GO:0043729,"Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate + H+.",2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity,molecular_function
74348,GO:0043731,"Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.",6-hydroxynicotinate 3-monooxygenase activity,molecular_function
74349,GO:0043732,"Catalysis of the reaction: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2.",6-hydroxynicotinate dehydrogenase activity,molecular_function
74350,GO:0043733,"Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.",DNA-3-methylbase glycosylase activity,molecular_function
74351,GO:0043737,Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.,deoxyribonuclease V activity,molecular_function
74352,GO:0043738,Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.,reduced coenzyme F420 dehydrogenase activity,molecular_function
74353,GO:0043739,"Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free uracil and leaving an apyrimidinic (AP) site.",G/U mismatch-specific uracil-DNA glycosylase activity,molecular_function
74354,GO:0043740,Catalysis of the reaction: GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H+ + 2 phosphate.,GTP cyclohydrolase IIa activity,molecular_function
74355,GO:0043741,Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.,alpha-aminoadipate acetyltransferase activity,molecular_function
74356,GO:0043743,"Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP.",LPPG:FO 2-phospho-L-lactate transferase activity,molecular_function
74357,GO:0043744,Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate.,N2-acetyl-L-aminoadipate kinase activity,molecular_function
74358,GO:0043748,"Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.",O-succinylbenzoate synthase activity,molecular_function
74359,GO:0043750,"Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.",phosphatidylinositol alpha-mannosyltransferase activity,molecular_function
74360,GO:0043751,Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP.,polyphosphate:AMP phosphotransferase activity,molecular_function
74361,GO:0043752,Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).,adenosylcobinamide kinase activity,molecular_function
74362,GO:0043754,"Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA. In addition to transferring the 2-methylpropanoyl group when acting on the oxoacid corresponding with valine, this activity also transfers the 3-methylbutanoyl and S-2-methylbutanoyl groups when acting on the oxo acids corresponding with leucine and isoleucine.",dihydrolipoamide branched chain acyltransferase activity,molecular_function
74363,GO:0043755,Catalysis of the reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate.,alpha-ribazole phosphatase activity,molecular_function
74364,GO:0043756,Catalysis of the reaction: adenosylcobinamide + H2O = (R)-1-aminopropan-2-ol + adenosylcobyrate.,adenosylcobinamide hydrolase activity,molecular_function
74365,GO:0043757,"Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.",adenosylcobinamide-phosphate synthase activity,molecular_function
74366,GO:0043758,Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.,acetate-CoA ligase (ADP-forming) activity,molecular_function
74367,GO:0043759,Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP + diphosphate + 2-methylbutanoyl-CoA.,2-methylbutanoate-CoA ligase activity,molecular_function
74368,GO:0043761,Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP.,archaetidylserine synthase activity,molecular_function
74369,GO:0043763,Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.,UTP:glucose-1-phosphate uridylyltransferase regulator activity,molecular_function
74370,GO:0043765,"Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.",T/G mismatch-specific endonuclease activity,molecular_function
74371,GO:0043766,Catalysis of the reaction: H+ + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys) = L-cysteinyl-tRNA(Cys) + phosphate.,Sep-tRNA:Cys-tRNA synthase activity,molecular_function
74372,GO:0043767,Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).,pyrrolysyl-tRNA synthetase activity,molecular_function
74373,GO:0043768,"Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.",S-ribosylhomocysteine lyase activity,molecular_function
74374,GO:0043769,"A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.",Tpg-containing telomere binding complex,cellular_component
74375,GO:0043770,Catalysis of the reaction: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H+ + S-adenosyl-L-homocysteine. Reaction substrates can have varying polyprenyl side chain length.,demethylmenaquinone methyltransferase activity,molecular_function
74376,GO:0043771,Catalysis of the reaction: ATP + cytidine = ADP + CMP.,cytidine kinase activity,molecular_function
74377,GO:0043772,Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.,acyl-phosphate glycerol-3-phosphate acyltransferase activity,molecular_function
74378,GO:0043773,"Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.",coenzyme F420-0 gamma-glutamyl ligase activity,molecular_function
74379,GO:0043774,Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate.,coenzyme F420-2 alpha-glutamyl ligase activity,molecular_function
74380,GO:0043776,Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.,cobalt-precorrin-6B C5-methyltransferase activity,molecular_function
74381,GO:0043777,Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2.,cobalt-precorrin-7 C15-methyltransferase activity,molecular_function
74382,GO:0043778,Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.,cobalt-precorrin-8 methylmutase activity,molecular_function
74383,GO:0043779,Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde + H+.,cobalt-precorrin-5A acetaldehyde-lyase activity,molecular_function
74384,GO:0043780,Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.,cobalt-precorrin-5B C1-methyltransferase activity,molecular_function
74385,GO:0043781,Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III.,cobalt-factor II C20-methyltransferase activity,molecular_function
74386,GO:0043782,Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.,cobalt-precorrin-3 C17-methyltransferase activity,molecular_function
74387,GO:0043785,Catalysis of the reaction: (E)-cinnamoyl-CoA + (R)-3-phenyllactate = (R)-3-phenyllactoyl-CoA + (E)-cinnamate.,cinnamoyl-CoA:phenyllactate CoA-transferase activity,molecular_function
74388,GO:0043786,Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.,cinnamate reductase activity,molecular_function
74389,GO:0043791,Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.,dimethylamine methyltransferase activity,molecular_function
74390,GO:0043792,"Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O = 2-formylglutarate + NH4.",enamidase activity,molecular_function
74391,GO:0043793,"Catalysis of the reaction: 4-hydroxybenzoate + 5-phospho-alpha-D-ribose 1-diphosphate + H+ = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate. Both 4-hydroxybenzoate and 4-aminobenzoate may be used as substrates, but only the former is known to be produced by methanogenic archaea.",beta-ribofuranosylaminobenzene 5'-phosphate synthase activity,molecular_function
74392,GO:0043794,Catalysis of the reaction: formate + 2 H+ + oxidized coenzyme F420-(gamma-L-Glu)(n) = CO2 + reduced coenzyme F420-(gamma-L-Glu)(n).,formate dehydrogenase (coenzyme F420) activity,molecular_function
74393,GO:0043795,Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H+.,glyceraldehyde oxidoreductase activity,molecular_function
74394,GO:0043796,Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.,glyceraldehyde dehydrogenase (NADP+) activity,molecular_function
74395,GO:0043797,Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin.,glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity,molecular_function
74396,GO:0043798,Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.,glycerate 2-kinase activity,molecular_function
74397,GO:0043799,Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH4+ + H2O2; (2) D-alanine + H2O + O2 = pyruvate + NH4+ + H2O2; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + H2O2; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + H2O2.,glycine oxidase activity,molecular_function
74398,GO:0043800,Catalysis of the reaction: D-arabino-hex-3-ulose 6-phosphate = beta-D-fructose 6-phosphate.,6-phospho-3-hexuloisomerase activity,molecular_function
74399,GO:0043801,Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.,hexulose-6-phosphate synthase activity,molecular_function
74400,GO:0043802,"Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H2O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H+ + hydrogenobyrinate a,c-diamide + 2 phosphate.","hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity",molecular_function
74401,GO:0043803,Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + spheroidene.,hydroxyneurosporene-O-methyltransferase activity,molecular_function
74402,GO:0043804,Catalysis of the reaction: imidazol-4-one + H2O = N-formimidoylglycine.,imidazolone hydrolase activity,molecular_function
74403,GO:0043805,Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.,indolepyruvate ferredoxin oxidoreductase activity,molecular_function
74404,GO:0043807,Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.,3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity,molecular_function
74405,GO:0043808,Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].,lyso-ornithine lipid acyltransferase activity,molecular_function
74406,GO:0043810,"Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.",ornithine-acyl [acyl carrier protein] N-acyltransferase activity,molecular_function
74407,GO:0043811,Catalysis of the reaction: a fatty acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].,phosphate:acyl-[acyl carrier protein] acyltransferase activity,molecular_function
74408,GO:0043812,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.",phosphatidylinositol-4-phosphate phosphatase activity,molecular_function
74409,GO:0043813,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate.","phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity",molecular_function
74410,GO:0043814,Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.,phospholactate guanylyltransferase activity,molecular_function
74411,GO:0043815,Catalysis of the reaction: ATP + formate + N1-(5-phospho-beta-D-ribosyl)glycinamide = ADP + H+ + N2-formyl-N1-(5-phospho-beta-D-ribosyl)glycinamide + phosphate.,phosphoribosylglycinamide formyltransferase 2 activity,molecular_function
74412,GO:0043816,Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).,phosphoserine-tRNA(Cys) ligase activity,molecular_function
74413,GO:0043817,Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite.,phosphosulfolactate synthase activity,molecular_function
74414,GO:0043818,Catalysis of the reaction: H+ + NADH + O2 + precorrin-3A = H2O + NAD+ + precorrin-3B.,precorrin-3B synthase activity,molecular_function
74415,GO:0043819,Catalysis of the reaction: S-adenosyl-L-methionine + H2O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H+ + precorrin-6X.,precorrin-6A synthase (deacetylating) activity,molecular_function
74416,GO:0043821,Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.,propionyl-CoA:succinate CoA-transferase activity,molecular_function
74417,GO:0043822,"Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.",ribonuclease M5 activity,molecular_function
74418,GO:0043823,Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.,spheroidene monooxygenase activity,molecular_function
74419,GO:0043824,Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H2O + NAD+ = N-succinyl-L-glutamate + 2 H+ + NADH.,succinylglutamate-semialdehyde dehydrogenase (NAD+) activity,molecular_function
74420,GO:0043825,Catalysis of the reaction: N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.,succinylornithine:2-oxoglutarate transaminase activity,molecular_function
74421,GO:0043827,Catalysis of the reaction: adenosine57/adenosine58 in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N1-methyladenosine57/N1-methyladenosine58 in tRNA + 2 S-adenosyl-L-homocysteine.,tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity,molecular_function
74422,GO:0043828,Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).,tRNA 2-selenouridine synthase activity,molecular_function
74423,GO:0043829,"Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH4+, in a tRNA-Ala molecule.",tRNA-specific adenosine-37 deaminase activity,molecular_function
74424,GO:0043831,Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.,thiosulfate dehydrogenase (quinone) activity,molecular_function
74425,GO:0043833,Catalysis of the reaction: [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M = [Co(I) methylamine-specific corrinoid protein] + H+ + methyl-coenzyme M. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.,[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase activity,molecular_function
74426,GO:0043834,Catalysis of the reaction: Co(I)-[trimethylamine-specific corrinoid protein] + H+ + trimethylamine = dimethylamine + methyl-Co(III)-[trimethylamine-specific corrinoid protein].,trimethylamine methyltransferase activity,molecular_function
74427,GO:0043836,Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate.,xanthine hydrolase activity,molecular_function
74428,GO:0043837,Catalysis of the reaction: L-valine + NAD+ + H2O = 3-methyl-2-oxobutanoate + NH4+ + NADH + H+.,L-valine dehydrogenase (NAD+) activity,molecular_function
74429,GO:0043838,Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.,phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity,molecular_function
74430,GO:0043839,Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.,lipid A phosphate methyltransferase activity,molecular_function
74431,GO:0043842,"Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.",Kdo transferase activity,molecular_function
74432,GO:0043843,Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.,ADP-specific glucokinase activity,molecular_function
74433,GO:0043844,"Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.",ADP-specific phosphofructokinase activity,molecular_function
74434,GO:0043845,"A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.","DNA polymerase III, proofreading complex",cellular_component
74435,GO:0043846,A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.,"DNA polymerase III, clamp loader complex",cellular_component
74436,GO:0043847,A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB).,"DNA polymerase III, clamp loader chi/psi subcomplex",cellular_component
74437,GO:0043849,"Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.",Ras palmitoyltransferase activity,molecular_function
74438,GO:0043850,"A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair.",RecFOR complex,cellular_component
74439,GO:0043852,Catalysis of the reaction: Co(I)-[methylamine-specific corrinoid protein] + methylamine + H+ = methyl-Co(III)-[methylamine-specific corrinoid protein] + NH4+.,monomethylamine methyltransferase activity,molecular_function
74440,GO:0043853,"A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol.",methanol-CoM methyltransferase complex,cellular_component
74441,GO:0043854,Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.,cyclic nucleotide-gated mechanosensitive monoatomic ion channel activity,molecular_function
74442,GO:0043855,Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.,cyclic nucleotide-activated monoatomic ion channel activity,molecular_function
74443,GO:0043856,"The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.",anti-sigma factor antagonist activity,molecular_function
74444,GO:0043857,Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H+ + phosphate.,N-acetylornithine carbamoyltransferase activity,molecular_function
74445,GO:0043858,Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out).,arginine:ornithine antiporter activity,molecular_function
74446,GO:0043860,Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).,cyanophycin synthetase activity,molecular_function
74447,GO:0043861,Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out).,agmatine:putrescine antiporter activity,molecular_function
74448,GO:0043862,Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).,arginine:agmatine antiporter activity,molecular_function
74449,GO:0043863,Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.,4-hydroxy-2-ketopimelate aldolase activity,molecular_function
74450,GO:0043864,Catalysis of the reaction: iH2O + indole-3-acetamide = (indol-3-yl)acetate + NH4+. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.,indoleacetamide hydrolase activity,molecular_function
74451,GO:0043865,Enables the transfer of methionine from one side of a membrane to the other.,methionine transmembrane transporter activity,molecular_function
74452,GO:0043866,Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin.,adenylyl-sulfate reductase (thioredoxin) activity,molecular_function
74453,GO:0043867,Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.,7-cyano-7-deazaguanine tRNA-ribosyltransferase activity,molecular_function
74454,GO:0043870,Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH.,N-acetyl-gamma-aminoadipyl-phosphate reductase (NADP+) activity,molecular_function
74455,GO:0043872,Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out).,lysine:cadaverine antiporter activity,molecular_function
74456,GO:0043873,Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.,pyruvate-flavodoxin oxidoreductase activity,molecular_function
74457,GO:0043874,"Catalysis of the reactions:5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate.",acireductone synthase activity,molecular_function
74458,GO:0043875,Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.,2-ketobutyrate formate-lyase activity,molecular_function
74459,GO:0043876,Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.,D-threonine aldolase activity,molecular_function
74460,GO:0043877,Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH4+.,galactosamine-6-phosphate isomerase activity,molecular_function
74461,GO:0043878,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.,glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity,molecular_function
74462,GO:0043879,Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).,glycolate transmembrane transporter activity,molecular_function
74463,GO:0043880,Catalysis of the reaction: butanoyl-CoA + NADP+ = (2E)-butenoyl-CoA + NADPH + H+. (2E)-butenoyl-CoA is also called crotonyl-CoA.,crotonyl-CoA reductase activity,molecular_function
74464,GO:0043881,Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.,mesaconyl-CoA hydratase activity,molecular_function
74465,GO:0043882,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).,malate:sodium symporter activity,molecular_function
74466,GO:0043883,Catalysis of the reaction: (S)-malate + H+ = (S)-lactate + CO2.,malolactic enzyme activity,molecular_function
74467,GO:0043884,Catalysis of the reaction: Co(I)-[corrinoid Fe-S protein] + acetyl-CoA + H+ = methyl-Co(III)-[corrinoid Fe-S protein] + CO + CoA.,CO-methylating acetyl-CoA synthase activity,molecular_function
74468,GO:0043885,Catalysis of the reaction: CO + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + 2 H+.,anaerobic carbon-monoxide dehydrogenase activity,molecular_function
74469,GO:0043886,"The action of a molecule that contributes to the structural integrity of a carboxysome shell, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO2.",structural constituent of carboxysome shell,molecular_function
74470,GO:0043887,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).,melibiose:sodium symporter activity,molecular_function
74471,GO:0043890,Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.,N-acetylgalactosamine-6-sulfatase activity,molecular_function
74472,GO:0043891,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.,"glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity",molecular_function
74473,GO:0043892,Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.,methylglyoxal reductase (NADPH) activity,molecular_function
74474,GO:0043893,Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).,acetate:monoatomic cation symporter activity,molecular_function
74475,GO:0043894,"Catalysis of the acetylation of a lysine of the enzyme acetyl-CoA ligase, using acetyl-CoA as substrate. In Bacillus subtilis, this is Lys609, but it may correspond to another position in orthologs. This acetylation results in inhibition of acetyl-CoA synthetase.",acetyl-CoA synthetase acetyltransferase activity,molecular_function
74476,GO:0043895,"Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.",cyclomaltodextrin glucanotransferase activity,molecular_function
74477,GO:0043896,Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.,"glucan 1,6-alpha-glucosidase activity",molecular_function
74478,GO:0043897,Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.,"glucan 1,4-alpha-maltohydrolase activity",molecular_function
74479,GO:0043898,"Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.","2,3-dihydroxybiphenyl 1,2-dioxygenase activity",molecular_function
74480,GO:0043899,Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.,phosphoserine:homoserine phosphotransferase activity,molecular_function
74481,GO:0043903,"Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.",regulation of biological process involved in symbiotic interaction,biological_process
74482,GO:0043904,Catalysis of the reaction: isochorismate = salicylate + pyruvate.,isochorismate pyruvate lyase activity,molecular_function
74483,GO:0043905,Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).,L-seryl-tRNA(Thr) hydrolase activity,molecular_function
74484,GO:0043906,Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).,Ala-tRNA(Pro) deacylase activity,molecular_function
74485,GO:0043907,Catalysis of the reaction: L-cysteinyl-tRNA(Pro) + H2O = tRNA(Pro) + L-cysteine + H+.,Cys-tRNA(Pro) deacylase activity,molecular_function
74486,GO:0043908,Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).,Ser(Gly)-tRNA(Ala) hydrolase activity,molecular_function
74487,GO:0043909,Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.,N-acetylcitrulline deacetylase activity,molecular_function
74488,GO:0043910,Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.,ATP:coenzyme F420 adenylyltransferase activity,molecular_function
74489,GO:0043911,Catalysis of the reaction: D-lysine + 2-oxoglutarate = 6-amino-2-oxohexanoate + L-glutamate.,D-lysine:2-oxoglutarate transaminase activity,molecular_function
74490,GO:0043914,Catalysis of the reaction: hydrogen sulfide + NAD(P)+ = sulfur + NAD(P)H.,NAD(P)H sulfur oxidoreductase (CoA-dependent) activity,molecular_function
74491,GO:0043915,Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).,L-seryl-tRNA(Sec) kinase activity,molecular_function
74492,GO:0043916,"Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.",DNA-7-methylguanine glycosylase activity,molecular_function
74493,GO:0043917,"Catalysis of the reaction: alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.","ribose 1,5-bisphosphate isomerase activity",molecular_function
74494,GO:0043918,Catalysis of the reaction: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine = aminopropylcadaverine + H+ + S-methyl-5'-thioadenosine.,cadaverine aminopropyltransferase activity,molecular_function
74495,GO:0043919,Catalysis of the reaction: agmatine + S-adenosyl 3-(methylsulfanyl)propylamine = H+ + N1-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine.,agmatine aminopropyltransferase activity,molecular_function
74496,GO:0043920,Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.,aminopropylagmatine ureohydrolase activity,molecular_function
74497,GO:0043921,A process in which a host organism alters or subverts viral transcription.,host-mediated perturbation of viral transcription,biological_process
74498,GO:0043922,"A process in which a host organism interferes with, inhibits or disrupts viral transcription.",host-mediated suppression of viral transcription,biological_process
74499,GO:0043923,"A process in which a host organism initiates, promotes, or enhances the normal execution of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.",host-mediated activation of viral transcription,biological_process
74500,GO:0043924,"Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.",suramin binding,molecular_function
74501,GO:0043931,"The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.",ossification involved in bone maturation,biological_process
74502,GO:0043932,"The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.",ossification involved in bone remodeling,biological_process
74503,GO:0043933,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.",protein-containing complex organization,biological_process
74504,GO:0043934,"The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.",sporulation,biological_process
74505,GO:0043935,"The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.",sexual sporulation resulting in formation of a cellular spore,biological_process
74506,GO:0043936,"The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.",asexual sporulation resulting in formation of a cellular spore,biological_process
74507,GO:0043937,"Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.",regulation of sporulation,biological_process
74508,GO:0043938,"Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.",positive regulation of sporulation,biological_process
74509,GO:0043939,"Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.",negative regulation of sporulation,biological_process
74510,GO:0043940,"Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.",regulation of sexual sporulation resulting in formation of a cellular spore,biological_process
74511,GO:0043941,"Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.",positive regulation of sexual sporulation resulting in formation of a cellular spore,biological_process
74512,GO:0043942,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.",negative regulation of sexual sporulation resulting in formation of a cellular spore,biological_process
74513,GO:0043943,"Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.",regulation of asexual sporulation resulting in formation of a cellular spore,biological_process
74514,GO:0043944,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.",negative regulation of asexual sporulation resulting in formation of a cellular spore,biological_process
74515,GO:0043945,"Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.",positive regulation of asexual sporulation resulting in formation of a cellular spore,biological_process
74516,GO:0043952,"The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.",protein transport by the Sec complex,biological_process
74517,GO:0043953,The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.,protein transport by the Tat complex,biological_process
74518,GO:0043954,The organization process that preserves a cellular component in a stable functional or structural state.,cellular component maintenance,biological_process
74519,GO:0043955,Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.,3-hydroxypropionyl-CoA synthetase activity,molecular_function
74520,GO:0043956,Catalysis of the reaction: 3-hydroxypropionyl-CoA = acryloyl-CoA + H2O.,3-hydroxypropionyl-CoA dehydratase activity,molecular_function
74521,GO:0043957,Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.,acryloyl-CoA reductase (NADPH) activity,molecular_function
74522,GO:0043958,Catalysis of the reaction: propanoyl-CoA + NAD+ = acryloyl-CoA + H+ + NADH.,acryloyl-CoA reductase (NADH) activity,molecular_function
74523,GO:0043959,"Catalysis of the reaction: (2R,3S)-beta-methylmalyl-CoA = glyoxylate + propanoyl-CoA.",L-erythro-3-methylmalyl-CoA lyase activity,molecular_function
74524,GO:0043961,Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.,succinyl-CoA:(R)-citramalate CoA-transferase activity,molecular_function
74525,GO:0043992,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).,histone H3K9 acetyltransferase activity,molecular_function
74526,GO:0043993,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).,histone H3K18 acetyltransferase activity,molecular_function
74527,GO:0043994,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).,histone H3K23 acetyltransferase activity,molecular_function
74528,GO:0043995,Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).,histone H4K5 acetyltransferase activity,molecular_function
74529,GO:0043996,Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).,histone H4K8 acetyltransferase activity,molecular_function
74530,GO:0043997,Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).,histone H4K12 acetyltransferase activity,molecular_function
74531,GO:0043998,Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.,histone H2A acetyltransferase activity,molecular_function
74532,GO:0043999,Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).,histone H2AK5 acetyltransferase activity,molecular_function
74533,GO:0044001,The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,migration in host,biological_process
74534,GO:0044002,"The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.",acquisition of nutrients from host,biological_process
74535,GO:0044003,A process in which a symbiont alters or subverts a biological process in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host process,biological_process
74536,GO:0044010,"A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",single-species biofilm formation,biological_process
74537,GO:0044011,"A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.",single-species biofilm formation on inanimate substrate,biological_process
74538,GO:0044012,Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).,histone H2AK9 acetyltransferase activity,molecular_function
74539,GO:0044013,Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.,histone H2B acetyltransferase activity,molecular_function
74540,GO:0044014,Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).,histone H2BK5 acetyltransferase activity,molecular_function
74541,GO:0044015,Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12).,histone H2BK12 acetyltransferase activity,molecular_function
74542,GO:0044016,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).,histone H3K4 acetyltransferase activity,molecular_function
74543,GO:0044017,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).,histone H3K27 acetyltransferase activity,molecular_function
74544,GO:0044018,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).,histone H3K36 acetyltransferase activity,molecular_function
74545,GO:0044020,"Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H4, producing histone H4R3me.",histone H4R3 methyltransferase activity,molecular_function
74546,GO:0044022,Catalysis of the reaction: histone H3-serine (position 28) + ATP = histone H3-phosphoserine (position 28) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 28 of histone H3.,histone H3S28 kinase activity,molecular_function
74547,GO:0044023,Catalysis of the reaction: histone H4-serine (position 1) + ATP = histone H4-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H4.,histone H4S1 kinase activity,molecular_function
74548,GO:0044024,Catalysis of the reaction: histone H2A-serine (position 1) + ATP = histone H2A-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H2A.,histone H2AS1 kinase activity,molecular_function
74549,GO:0044025,Catalysis of the reaction: histone H2B-serine (position 14) + ATP = histone H2B-phosphoserine (position 14) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 14 of histone H2B.,histone H2BS14 kinase activity,molecular_function
74550,GO:0044027,An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes.,negative regulation of gene expression via chromosomal CpG island methylation,biological_process
74551,GO:0044029,An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.,positive regulation of gene expression via chromosomal CpG island demethylation,biological_process
74552,GO:0044036,"The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.",cell wall macromolecule metabolic process,biological_process
74553,GO:0044038,The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.,cell wall macromolecule biosynthetic process,biological_process
74554,GO:0044042,"The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.",glucan metabolic process,biological_process
74555,GO:0044053,The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm.,translocation of peptides or proteins into host cell cytoplasm,biological_process
74556,GO:0044057,"Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.",regulation of system process,biological_process
74557,GO:0044058,"Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",regulation of digestive system process,biological_process
74558,GO:0044060,"Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.",regulation of endocrine process,biological_process
74559,GO:0044062,"Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.",regulation of excretion,biological_process
74560,GO:0044065,"Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.",regulation of respiratory system process,biological_process
74561,GO:0044066,The process in which an organism effects a change that impairs the structure or function of the host cell nucleus.,symbiont-mediated disruption of host cell nucleus,biological_process
74562,GO:0044067,The process in which an organism effects a change that impairs the structure or temporarily subverts the host intercellular junction. Intercellular junction include tight junctions and adherens junctions.,symbiont-mediated perturbation of host cell-cell junction,biological_process
74563,GO:0044068,A process in which a symbiont alters or subverts a cellular biological process in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cellular process,biological_process
74564,GO:0044070,"Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of monoatomic anion transport,biological_process
74565,GO:0044071,A process in which a symbiont interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cell cycle progression,biological_process
74566,GO:0044075,A process in which a symbiont alters or subverts vacuole organization in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host vacuole organization,biological_process
74567,GO:0044077,"A process in which a symbiont initiates, promotes, or enhances host receptor-mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host receptor-mediated endocytosis,biological_process
74568,GO:0044079,A process in which a symbiont alters or subverts the regulated release of a neurotransmitter from a cell in its host organism.,symbiont-mediated perturbation of host neurotransmitter secretion,biological_process
74569,GO:0044082,A process in which a symbiont alters or subverts a small GTPase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host small GTPase-mediated signal transduction,biological_process
74570,GO:0044083,A process in which a symbiont alters a Rho protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host Rho small GTPase signal transduction,biological_process
74571,GO:0044084,"Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins.",host cell membrane pore complex,cellular_component
74572,GO:0044085,"A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.",cellular component biogenesis,biological_process
74573,GO:0044087,"Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.",regulation of cellular component biogenesis,biological_process
74574,GO:0044088,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.",regulation of vacuole organization,biological_process
74575,GO:0044089,"Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.",positive regulation of cellular component biogenesis,biological_process
74576,GO:0044090,"Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.",positive regulation of vacuole organization,biological_process
74577,GO:0044091,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.",membrane biogenesis,biological_process
74578,GO:0044092,"Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.",negative regulation of molecular function,biological_process
74579,GO:0044093,"Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.",positive regulation of molecular function,biological_process
74580,GO:0044094,"Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.",host cell nuclear part,cellular_component
74581,GO:0044095,That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.,host cell nucleoplasm,cellular_component
74582,GO:0044096,A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers.,type IV pilus,cellular_component
74583,GO:0044097,"The controlled release of proteins or DNA by a cell, via the type IV secretion system.",secretion by the type IV secretion system,biological_process
74584,GO:0044098,"The controlled release of DNA by a cell, via the type IV secretion system.",DNA secretion by the type IV secretion system,biological_process
74585,GO:0044099,"A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell.",polar tube,cellular_component
74586,GO:0044100,The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms.,sporoplasm,cellular_component
74587,GO:0044101,Catalysis of the reaction: (3R)-citramalyl-CoA = pyruvate + acetyl-CoA.,(3R)-citramalyl-CoA lyase activity,molecular_function
74588,GO:0044102,Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor.,purine deoxyribosyltransferase activity,molecular_function
74589,GO:0044103,"Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.",L-arabinose 1-dehydrogenase (NADP+) activity,molecular_function
74590,GO:0044104,"Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + 2 H+.","2,5-dioxovalerate dehydrogenase (NAD+) activity",molecular_function
74591,GO:0044105,Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.,L-xylulose reductase (NADH) activity,molecular_function
74592,GO:0044111,"The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.",formation of structure involved in a symbiotic process,biological_process
74593,GO:0044114,"The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.",development of symbiont in host,biological_process
74594,GO:0044127,"Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.",regulation of development of symbiont in host,biological_process
74595,GO:0044129,"Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.",positive regulation of development of symbiont in host,biological_process
74596,GO:0044145,"Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.",modulation of formation of structure involved in a symbiotic process,biological_process
74597,GO:0044155,"A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host caveola,cellular_component
74598,GO:0044156,"A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.",host cell junction,cellular_component
74599,GO:0044157,"A prolongation or process extending from a host cell, e.g. a flagellum or axon.",host cell projection,cellular_component
74600,GO:0044158,"The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.",host cell wall,cellular_component
74601,GO:0044159,"A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynt...",host thylakoid,cellular_component
74602,GO:0044160,The pigmented membrane of any host thylakoid.,host thylakoid membrane,cellular_component
74603,GO:0044161,"A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.",host cell cytoplasmic vesicle,cellular_component
74604,GO:0044162,The lipid bilayer surrounding a host cell cytoplasmic vesicle.,host cell cytoplasmic vesicle membrane,cellular_component
74605,GO:0044163,"A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division...",host cytoskeleton,cellular_component
74606,GO:0044164,"The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",host cell cytosol,cellular_component
74607,GO:0044165,"The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).",host cell endoplasmic reticulum,cellular_component
74608,GO:0044166,The volume enclosed by the membranes of the host cell endoplasmic reticulum.,host cell endoplasmic reticulum lumen,cellular_component
74609,GO:0044167,The lipid bilayer surrounding the host cell endoplasmic reticulum.,host cell endoplasmic reticulum membrane,cellular_component
74610,GO:0044168,"The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.",host cell rough endoplasmic reticulum,cellular_component
74611,GO:0044169,The lipid bilayer surrounding the host cell rough endoplasmic reticulum.,host cell rough endoplasmic reticulum membrane,cellular_component
74612,GO:0044170,"The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface.",host cell smooth endoplasmic reticulum,cellular_component
74613,GO:0044171,The lipid bilayer surrounding the host cell smooth endoplasmic reticulum.,host cell smooth endoplasmic reticulum membrane,cellular_component
74614,GO:0044172,"A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.",host cell endoplasmic reticulum-Golgi intermediate compartment,cellular_component
74615,GO:0044173,The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system.,host cell endoplasmic reticulum-Golgi intermediate compartment membrane,cellular_component
74616,GO:0044174,A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.,host cell endosome,cellular_component
74617,GO:0044175,The lipid bilayer surrounding a host cell endosome.,host cell endosome membrane,cellular_component
74618,GO:0044176,"Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.",host cell filopodium,cellular_component
74619,GO:0044177,"A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.",host cell Golgi apparatus,cellular_component
74620,GO:0044178,The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.,host cell Golgi membrane,cellular_component
74621,GO:0044179,"The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.",hemolysis in another organism,biological_process
74622,GO:0044180,"The process in which a unicellular organism grows in a threadlike, filamentous shape.",filamentous growth of a unicellular organism,biological_process
74623,GO:0044181,"The process in which a multicellular organism grows in a threadlike, filamentous shape.",filamentous growth of a multicellular organism,biological_process
74624,GO:0044182,"The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.",filamentous growth of a population of unicellular organisms,biological_process
74625,GO:0044183,Binding to a protein or a protein-containing complex to assist the protein folding process.,protein folding chaperone,molecular_function
74626,GO:0044184,"A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.",host cell late endosome,cellular_component
74627,GO:0044185,The lipid bilayer surrounding a host cell late endosome.,host cell late endosome membrane,cellular_component
74628,GO:0044186,Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins.,host cell lipid droplet,cellular_component
74629,GO:0044187,"A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.",host cell lysosome,cellular_component
74630,GO:0044188,The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm.,host cell lysosomal membrane,cellular_component
74631,GO:0044190,The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.,host cell mitochondrial envelope,cellular_component
74632,GO:0044191,Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.,host cell mitochondrial membrane,cellular_component
74633,GO:0044192,"The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.",host cell mitochondrial inner membrane,cellular_component
74634,GO:0044193,"The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope.",host cell mitochondrial outer membrane,cellular_component
74635,GO:0044194,A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.,cytolytic granule,cellular_component
74636,GO:0044195,"Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.",nucleoplasmic reticulum,cellular_component
74637,GO:0044196,"A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.",host cell nucleolus,cellular_component
74638,GO:0044197,"Binding to a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT.",Rel homology domain binding,molecular_function
74639,GO:0044198,Binding to a TRAF-type zinc finger domain of a protein.,zf-TRAF domain binding,molecular_function
74640,GO:0044199,"The double lipid bilayer that encloses the host cell nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport.",host cell nuclear envelope,cellular_component
74641,GO:0044200,Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.,host cell nuclear membrane,cellular_component
74642,GO:0044201,"The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.",host cell nuclear inner membrane,cellular_component
74643,GO:0044202,"The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.",host cell nuclear outer membrane,cellular_component
74644,GO:0044203,"The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.",host cell nuclear lamina,cellular_component
74645,GO:0044204,"A dynamic, proteinaceous framework within the nucleus of host eukaryotic cells, composed of proteins and RNA, that provides structural support for chromatin organization, gene regulation, and nuclear processes.",host cell nuclear matrix,cellular_component
74646,GO:0044205,"The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.",'de novo' UMP biosynthetic process,biological_process
74647,GO:0044206,"Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.",UMP salvage,biological_process
74648,GO:0044207,"A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).",translation initiation ternary complex,cellular_component
74649,GO:0044208,The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).,'de novo' AMP biosynthetic process,biological_process
74650,GO:0044209,"The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.",AMP salvage,biological_process
74651,GO:0044210,The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.,'de novo' CTP biosynthetic process,biological_process
74652,GO:0044211,"Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.",CTP salvage,biological_process
74653,GO:0044217,Any constituent part of a secondary organism with which the first organism is interacting.,other organism part,cellular_component
74654,GO:0044218,The cell membrane of a secondary organism with which the first organism is interacting.,other organism cell membrane,cellular_component
74655,GO:0044219,"A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.",host cell plasmodesma,cellular_component
74656,GO:0044220,"The host cell cytoplasm situated near, or occurring around, the host nucleus.",host cell perinuclear region of cytoplasm,cellular_component
74657,GO:0044221,The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.,host cell synapse,cellular_component
74658,GO:0044222,"An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.",anammoxosome,cellular_component
74659,GO:0044223,"A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.",pirellulosome,cellular_component
74660,GO:0044224,A region of an axon near a node of Ranvier that is between the paranode and internode regions.,juxtaparanode region of axon,cellular_component
74661,GO:0044225,Portion of a neuron cell soma closest to the point where the apical dendrite emerges.,apical pole of neuron,cellular_component
74662,GO:0044226,Portion of a neuron cell soma closest to the point where the basilar dendrite emerges.,basal pole of neuron,cellular_component
74663,GO:0044227,"A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.",methane-oxidizing organelle,cellular_component
74664,GO:0044228,The external part of the host cell wall and/or host plasma membrane.,host cell surface,cellular_component
74665,GO:0044229,The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).,host cell periplasmic space,cellular_component
74666,GO:0044230,"An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.",host cell envelope,cellular_component
74667,GO:0044231,"A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.",host cell presynaptic membrane,cellular_component
74668,GO:0044232,"A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.",organelle membrane contact site,cellular_component
74669,GO:0044233,"A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.",mitochondria-associated endoplasmic reticulum membrane contact site,cellular_component
74670,GO:0044238,"The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.",primary metabolic process,biological_process
74671,GO:0044241,"The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.",lipid digestion,biological_process
74672,GO:0044245,"The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.",polysaccharide digestion,biological_process
74673,GO:0044256,"The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.",protein digestion,biological_process
74674,GO:0044258,The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.,intestinal lipid catabolic process,biological_process
74675,GO:0044269,"The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.",glycerol ether catabolic process,biological_process
74676,GO:0044272,"The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.",sulfur compound biosynthetic process,biological_process
74677,GO:0044273,"The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.",sulfur compound catabolic process,biological_process
74678,GO:0044277,A process that results in the breakdown of the cell wall.,cell wall disassembly,biological_process
74679,GO:0044278,"The disruption of the cell wall of another organism by a venom, leading to damage or temporary subversion of the cell wall.",venom-mediated disruption of cell wall in another organism,biological_process
74680,GO:0044280,"Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.",subplasmalemmal coating,cellular_component
74681,GO:0044281,"The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.",small molecule metabolic process,biological_process
74682,GO:0044282,"The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.",small molecule catabolic process,biological_process
74683,GO:0044283,"The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.",small molecule biosynthetic process,biological_process
74684,GO:0044284,A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.,mitochondrial crista junction,cellular_component
74685,GO:0044286,"A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.",peg and socket contact,cellular_component
74686,GO:0044288,"A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.",puncta adhaerentia,cellular_component
74687,GO:0044289,Sites of close apposition of the inner and outer mitochondrial membrane.,mitochondrial inner-outer membrane contact site,cellular_component
74688,GO:0044290,"The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.",mitochondrial intracristal space,cellular_component
74689,GO:0044291,"Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.",cell-cell contact zone,cellular_component
74690,GO:0044292,"A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.",dendrite terminus,cellular_component
74691,GO:0044293,Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).,dendriole,cellular_component
74692,GO:0044294,The migrating motile tip of a growing nerve cell dendrite.,dendritic growth cone,cellular_component
74693,GO:0044295,The migrating motile tip of a growing nerve cell axon.,axonal growth cone,cellular_component
74694,GO:0044296,"The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.",dendritic tuft,cellular_component
74695,GO:0044297,"The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.",cell body,cellular_component
74696,GO:0044298,"The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.",cell body membrane,cellular_component
74697,GO:0044299,The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.,C-fiber,cellular_component
74698,GO:0044300,"An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enla...",cerebellar mossy fiber,cellular_component
74699,GO:0044301,"The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single cli...",climbing fiber,cellular_component
74700,GO:0044302,Hippocampal mossy fiber produced by dentate gyrus granule cells.,dentate gyrus mossy fiber,cellular_component
74701,GO:0044303,Any of the smaller branches of an axon that emanate from the main axon cylinder.,axon collateral,cellular_component
74702,GO:0044304,"The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.",main axon,cellular_component
74703,GO:0044305,The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.,calyx of Held,cellular_component
74704,GO:0044306,"The specialized, terminal region of a neuron projection such as an axon or a dendrite.",neuron projection terminus,cellular_component
74705,GO:0044307,A dendrite arising from another dendrite.,dendritic branch,cellular_component
74706,GO:0044308,"A spine that originates from the axon, usually from the initial segment.",axonal spine,cellular_component
74707,GO:0044309,"A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.",neuron spine,cellular_component
74708,GO:0044310,"A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.",osmiophilic body,cellular_component
74709,GO:0044311,"A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.",exoneme,cellular_component
74710,GO:0044312,"A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation.",crystalloid,cellular_component
74711,GO:0044313,"A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein.",protein K6-linked deubiquitination,biological_process
74712,GO:0044314,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.",protein K27-linked ubiquitination,biological_process
74713,GO:0044315,"The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system.",protein secretion by the type VII secretion system,biological_process
74714,GO:0044316,"A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).",cone cell pedicle,cellular_component
74715,GO:0044317,A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.,rod spherule,cellular_component
74716,GO:0044319,The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.,"wound healing, spreading of cells",biological_process
74717,GO:0044320,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.",cellular response to leptin stimulus,biological_process
74718,GO:0044321,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism].",response to leptin,biological_process
74719,GO:0044322,"A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.",endoplasmic reticulum quality control compartment,cellular_component
74720,GO:0044323,"Binding to a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.",retinoic acid-responsive element binding,molecular_function
74721,GO:0044325,"Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.",transmembrane transporter binding,molecular_function
74722,GO:0044326,Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.,dendritic spine neck,cellular_component
74723,GO:0044327,"Distal part of the dendritic spine, that carries the post-synaptic density.",dendritic spine head,cellular_component
74724,GO:0044331,"The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.",cell-cell adhesion mediated by cadherin,biological_process
74725,GO:0044336,"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process.",canonical Wnt signaling pathway involved in negative regulation of apoptotic process,biological_process
74726,GO:0044337,"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process.",canonical Wnt signaling pathway involved in positive regulation of apoptotic process,biological_process
74727,GO:0044338,"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.",canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation,biological_process
74728,GO:0044341,"The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.",sodium-dependent phosphate transport,biological_process
74729,GO:0044342,"The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.",type B pancreatic cell proliferation,biological_process
74730,GO:0044344,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.",cellular response to fibroblast growth factor stimulus,biological_process
74731,GO:0044345,"The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.",stromal-epithelial cell signaling involved in prostate gland development,biological_process
74732,GO:0044346,"Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.",fibroblast apoptotic process,biological_process
74733,GO:0044347,The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.,cell wall polysaccharide catabolic process,biological_process
74734,GO:0044348,"The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.",plant-type cell wall cellulose catabolic process,biological_process
74735,GO:0044350,"An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm.",micropinocytosis,biological_process
74736,GO:0044351,"An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.",macropinocytosis,biological_process
74737,GO:0044352,"A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis.",pinosome,cellular_component
74738,GO:0044353,"A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis.",micropinosome,cellular_component
74739,GO:0044354,"A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.",macropinosome,cellular_component
74740,GO:0044355,A defense process that protects an organism from invading foreign DNA.,clearance of foreign intracellular DNA,biological_process
74741,GO:0044357,Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.,regulation of rRNA stability,biological_process
74742,GO:0044358,A process in which an organism causes vascular damage and hemorrhage in another organism via the action of a venom.,venom-mediated hemorrhage,biological_process
74743,GO:0044373,"Binding to a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators.",cytokinin binding,molecular_function
74744,GO:0044374,"The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.","sequence-specific DNA binding, bending",molecular_function
74745,GO:0044375,"Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.",regulation of peroxisome size,biological_process
74746,GO:0044377,"Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.","RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending",molecular_function
74747,GO:0044378,"The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.","non-sequence-specific DNA binding, bending",molecular_function
74748,GO:0044379,"A process in which a protein is transported to, or maintained in, an actin cortical patch.",protein localization to actin cortical patch,biological_process
74749,GO:0044380,"A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.",protein localization to cytoskeleton,biological_process
74750,GO:0044381,The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.,glucose import in response to insulin stimulus,biological_process
74751,GO:0044382,"The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation.",CLRC complex localization to heterochromatin,biological_process
74752,GO:0044383,"A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell.",host chromosome,cellular_component
74753,GO:0044384,"The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell.",host outer membrane,cellular_component
74754,GO:0044387,"The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.",negative regulation of protein kinase activity by regulation of protein phosphorylation,biological_process
74755,GO:0044388,"Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme.",small protein activating enzyme binding,molecular_function
74756,GO:0044389,"Binding to a ubiquitin-like protein ligase, such as ubiquitin-ligase.",ubiquitin-like protein ligase binding,molecular_function
74757,GO:0044390,Binding to a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.,ubiquitin-like protein conjugating enzyme binding,molecular_function
74758,GO:0044391,Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.,ribosomal subunit,cellular_component
74759,GO:0044393,"A dynamic, actin-rich projection extending from the surface of a migrating animal cell.",microspike,cellular_component
74760,GO:0044394,The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.,protein malonylation,biological_process
74761,GO:0044395,The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.,protein targeting to vacuolar membrane,biological_process
74762,GO:0044396,"A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.",actin cortical patch organization,biological_process
74763,GO:0044398,A process by which an organism causes swelling of soft tissues in another organism via the action of a venom. Edema is the result of excess water accumulation in tissues.,venom-mediated edema,biological_process
74764,GO:0044399,"A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",multi-species biofilm formation,biological_process
74765,GO:0044403,"A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits whil...",biological process involved in symbiotic interaction,biological_process
74766,GO:0044406,"The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.",adhesion of symbiont to host,biological_process
74767,GO:0044407,"A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.",single-species biofilm formation in or on host organism,biological_process
74768,GO:0044409,"Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont entry into host,biological_process
74769,GO:0044414,"A process in which a symbiont interferes with, inhibits or disrupts the normal execution of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host defenses,biological_process
74770,GO:0044417,The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,translocation of molecules into host,biological_process
74771,GO:0044419,Any process evolved to enable an interaction with an organism of a different species.,biological process involved in interspecies interaction between organisms,biological_process
74772,GO:0044423,"Any constituent part of a virion, a complete fully infectious extracellular virus particle.",virion component,cellular_component
74773,GO:0044458,"The aggregation, arrangement and bonding together of a set of components to form a motile cilium.",motile cilium assembly,biological_process
74774,GO:0044467,"The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.",glial cell-derived neurotrophic factor production,biological_process
74775,GO:0044468,A process in which an organism alters or subverts blood coagulation in another organism via the action of a venom.,venom-mediated perturbation of blood coagulation,biological_process
74776,GO:0044469,"A process in which an organism initiates, promotes, or enhances blood coagulation in another organism via the action of a venom.",venom-mediated blood coagulation,biological_process
74777,GO:0044470,A process in which an organism inhibits or disrupts blood coagulation in another organism via the action of a venom.,venom-mediated suppression of blood coagulation,biological_process
74778,GO:0044471,"A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism.",venom-mediated pore formation in membrane of another organism,biological_process
74779,GO:0044472,A process in which an organism alters or subverts the activity of a calcium channel in another organism via the action of a venom.,venom-mediated perturbation of calcium channel activity,biological_process
74780,GO:0044473,A process in which an organism inhibits or disrupts the activity of a calcium channel in another organism via the action of a venom.,venom-mediated inhibition of calcium channel activity,biological_process
74781,GO:0044474,A process in which an organism inhibits or disrupts the activity of a voltage-gated calcium channel in another organism via the action of a venom.,venom-mediated inhibition of voltage-gated calcium channel activity,biological_process
74782,GO:0044475,A process in which an organism inhibits or disrupts the activity of a high voltage-gated calcium channel in another organism via the action of a venom.,venom-mediated inhibition of high voltage-gated calcium channel activity,biological_process
74783,GO:0044476,A process in which an organism inhibits or disrupts the activity of a low voltage-gated calcium channel in another organism via the action of a venom.,venom-mediated inhibition of low voltage-gated calcium channel activity,biological_process
74784,GO:0044477,A process in which an organism inhibits or disrupts platelet aggregation in another organism via the action of a venom.,venom-mediated suppression of platelet aggregation,biological_process
74785,GO:0044478,"A process in which an organism initiates, promotes, or enhances platelet aggregation in another organism via the action of a venom.",venom-mediated platelet aggregation,biological_process
74786,GO:0044479,A process in which an organism alters or subverts mast cell degranulation in another organism via the action of a venom.,venom-mediated perturbation of mast cell degranulation,biological_process
74787,GO:0044480,"A process in which an organism initiates, promotes, or enhances mast cell degranulation in another organism via the action of a venom.",venom-mediated mast cell degranulation,biological_process
74788,GO:0044483,A process in which an organism alters or subverts hemostasis in another organism via the action of a venom. Hemostasis is the mechanism that leads to cessation of bleeding from a blood vessel.,venom-mediated perturbation of hemostasis,biological_process
74789,GO:0044484,"A process in which an organism causes fibrinolysis in another organism via the action of a venom. Fibrinolysis is a process that solubilizes fibrin in the blood, chiefly by the proteolytic action of plasmin.",venom-mediated fibrinolysis,biological_process
74790,GO:0044485,"A process in which an organism initiates, promotes, or enhances fibrinogenolysis in another organism via the action of a venom. Fibrinogenolysis is the degradation of fibrinogen by proteolytic cleavage.",venom-mediated fibrinogenolysis,biological_process
74791,GO:0044487,A process in which an organism alters or subverts the transmission of a nerve impulse in another organism via the action of a venom.,venom-mediated perturbation of transmission of nerve impulse,biological_process
74792,GO:0044492,A process in which an organism alters or subverts the activity of a voltage-gated sodium channel in another organism via the action of a venom.,venom-mediated perturbation of voltage-gated sodium channel activity,biological_process
74793,GO:0044493,A process in which an organism inhibits or disrupts the activity of a voltage-gated sodium channel in another organism via the action of a venom.,venom-mediated inhibition of voltage-gated sodium channel activity,biological_process
74794,GO:0044494,"A process in which an organism initiates, promotes, or enhances the activity of a voltage-gated sodium channel in another organism via the action of a venom.",venom-mediated activation of voltage-gated sodium channel activity,biological_process
74795,GO:0044499,"A process in which an organism initiates, promotes, or enhances the narrowing (constriction) of blood vessels by small muscles in their walls in another organism via the action of a venom, concomittantly increasing blood pressure in the bitten/stung organism.",venom-mediated vasoconstriction,biological_process
74796,GO:0044508,Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.,glucagon-like peptide 1 receptor activity,molecular_function
74797,GO:0044509,A process in which an organism alters or subverts a signal transduction pathway in another organism via the action of a venom.,venom-mediated perturbation of signal transduction,biological_process
74798,GO:0044513,A process in which an organism alters or subverts a G protein-coupled receptor signaling pathway in another organism via the action of a venom.,venom-mediated perturbation of G protein-coupled receptor signaling pathway,biological_process
74799,GO:0044514,"A process in which an organism initiates, promotes, or enhances a G protein-coupled receptor signaling pathway in another organism via the action of a venom.",venom-mediated activation of G protein-coupled receptor signaling pathway,biological_process
74800,GO:0044521,"A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.",venom-mediated muscle damage in another organism,biological_process
74801,GO:0044522,"A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism.",venom-mediated myocyte killing in another organism,biological_process
74802,GO:0044523,"A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of a cell.",venom-mediated disruption of extracellular matrix in another organism,biological_process
74803,GO:0044524,The modification of a protein amino acid by the addition of sulfur.,protein sulfhydration,biological_process
74804,GO:0044525,"The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.",peptidyl-cystine sulfhydration,biological_process
74805,GO:0044528,Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.,regulation of mitochondrial mRNA stability,biological_process
74806,GO:0044529,Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs.,regulation of mitochondrial rRNA stability,biological_process
74807,GO:0044530,"Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.",supraspliceosomal complex,cellular_component
74808,GO:0044535,"Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + O2 = a very-long-chain (2E)-enoyl-CoA + H2O2.",very-long-chain fatty acyl-CoA oxidase activity,molecular_function
74809,GO:0044536,"The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism.",venom-mediated depletion of circulating fibrinogen,biological_process
74810,GO:0044537,Any process that modulates the quantity of fibrinogen circulating in the bloodstream.,regulation of circulating fibrinogen levels,biological_process
74811,GO:0044538,"The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.",host cell periphery,cellular_component
74812,GO:0044539,The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid import into cell,biological_process
74813,GO:0044540,Catalysis of the reaction: L-cystine + H2O = S-sulfanyl-L-cysteine + pyruvate + NH4+.,L-cystine L-cysteine-lyase (deaminating) activity,molecular_function
74814,GO:0044542,"A process in which a symbiont initiates, promotes, or enhances the normal activation of plasminogen, the pathway resulting in the processing of inactive plasminogen to active plasmin in the host organism. This can facilitate the dissemination of the symbiont into host tissues. It can also be used to destroy complement, opsonins as well as antibacterial proteins like histones.",symbiont-mediated activation of host plasminogen,biological_process
74815,GO:0044544,"A process in which an organism initiates, promotes, or enhances the activation of plasminogen into plasmin in another organism via the action of a venom. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.",venom-mediated plasminogen activation,biological_process
74816,GO:0044545,"A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.",NSL complex,cellular_component
74817,GO:0044546,"The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.",NLRP3 inflammasome complex assembly,biological_process
74818,GO:0044547,Binding to a DNA topoisomerase.,DNA topoisomerase binding,molecular_function
74819,GO:0044548,"Binding to a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.",S100 protein binding,molecular_function
74820,GO:0044549,Binding to a GTP cyclohydrolase.,GTP cyclohydrolase binding,molecular_function
74821,GO:0044550,"The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.",secondary metabolite biosynthetic process,biological_process
74822,GO:0044551,"A process in which an organism initiates, promotes, or enhances the widening of blood vessels by small muscles in their walls in another organism via the action of a venom, concomittantly reducing blood pressure in the bitten/stung organism.",venom-mediated vasodilation,biological_process
74823,GO:0044556,A process in which an organism slows down the heart rate in another organism via the action of a venom.,venom-mediated reduction of heart rate,biological_process
74824,GO:0044557,"A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.",relaxation of smooth muscle,biological_process
74825,GO:0044558,A process in which the extent of smooth muscle contraction is reduced in the uterus.,uterine smooth muscle relaxation,biological_process
74826,GO:0044559,A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.,venom-mediated perturbation of voltage-gated potassium channel activity,biological_process
74827,GO:0044560,A process in which an organism alters or subverts the activity of an ion channel in another organism via the action of a venom.,venom-mediated perturbation of ion channel activity,biological_process
74828,GO:0044562,A process in which an organism inhibits or disrupts the activity of a  voltage-gated potassium channel in another organism via the action of a venom.,venom-mediated inhibition of voltage-gated potassium channel activity,biological_process
74829,GO:0044565,"The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.",dendritic cell proliferation,biological_process
74830,GO:0044566,A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.,chondrocyte activation,biological_process
74831,GO:0044567,"A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.",primary cell wall cellulose synthase complex,cellular_component
74832,GO:0044568,"A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.",secondary cell wall cellulose synthase complex,cellular_component
74833,GO:0044569,A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.,[Ni-Fe] hydrogenase complex,cellular_component
74834,GO:0044570,"A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.",starch utilization system complex,cellular_component
74835,GO:0044571,The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.,[2Fe-2S] cluster assembly,biological_process
74836,GO:0044572,The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.,[4Fe-4S] cluster assembly,biological_process
74837,GO:0044573,"The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.",nitrogenase P cluster assembly,biological_process
74838,GO:0044574,"The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.",starch utilization system complex assembly,biological_process
74839,GO:0044575,"The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.",cellulosome assembly,biological_process
74840,GO:0044577,"The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, into ethanol.",D-xylose fermentation,biological_process
74841,GO:0044578,The chemical reactions and pathway resulting in the formation of butyryl-CoA.,butyryl-CoA biosynthetic process,biological_process
74842,GO:0044580,The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.,butyryl-CoA catabolic process,biological_process
74843,GO:0044583,Binding to cellotriose.,cellotriose binding,molecular_function
74844,GO:0044584,"Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers.",cellodextrin binding,molecular_function
74845,GO:0044585,"Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.",cellobiose binding,molecular_function
74846,GO:0044586,"Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.",cellotetraose binding,molecular_function
74847,GO:0044587,"Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.",cellopentaose binding,molecular_function
74848,GO:0044588,"Binding to laminaribiose, a disaccharide.",laminaribiose binding,molecular_function
74849,GO:0044589,Binding to pectin.,pectin binding,molecular_function
74850,GO:0044590,"Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.",iron-sulfur-molybdenum cofactor binding,molecular_function
74851,GO:0044591,"A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.",response to amylopectin,biological_process
74852,GO:0044592,"A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.",response to pullulan,biological_process
74853,GO:0044593,"The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.",iron-sulfur-molybdenum cofactor assembly,biological_process
74854,GO:0044594,Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.,17-beta-hydroxysteroid dehydrogenase (NAD+) activity,molecular_function
74855,GO:0044597,"The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.",daunorubicin metabolic process,biological_process
74856,GO:0044598,"The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.",doxorubicin metabolic process,biological_process
74857,GO:0044599,"An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.",AP-5 adaptor complex,cellular_component
74858,GO:0044600,Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.,protein guanylyltransferase activity,molecular_function
74859,GO:0044601,The removal of a nucleotide from a protein amino acid.,protein denucleotidylation,biological_process
74860,GO:0044602,The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.,protein deadenylylation,biological_process
74861,GO:0044603,Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.,protein adenylylhydrolase activity,molecular_function
74862,GO:0044604,"Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.",ABC-type phytochelatin transporter activity,molecular_function
74863,GO:0044605,Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.,phosphocholine transferase activity,molecular_function
74864,GO:0044606,Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.,phosphocholine hydrolase activity,molecular_function
74865,GO:0044609,A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.,DBIRD complex,cellular_component
74866,GO:0044610,Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other.,FMN transmembrane transporter activity,molecular_function
74867,GO:0044611,"A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referre...",nuclear pore inner ring,cellular_component
74868,GO:0044612,"A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are someti...",nuclear pore linkers,cellular_component
74869,GO:0044613,"The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucle...",nuclear pore central transport channel,cellular_component
74870,GO:0044614,"Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.",nuclear pore cytoplasmic filaments,cellular_component
74871,GO:0044615,"A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.",nuclear pore nuclear basket,cellular_component
74872,GO:0044616,A process in which an organism induces paralysis in another organism via the action of a venom. Paralysis is the loss of the ability to voluntarily control muscles. This can occur by blocking nerve signals at the neuromuscular junction or by directly interfering with muscle contraction.,venom-mediated paralysis,biological_process
74873,GO:0044617,"A process in which an organism initiates, promotes, or enhances the relaxation of smooth muscle in another organism via the action of a venom.",venom-mediated smooth muscle relaxation,biological_process
74874,GO:0044620,Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).,ACP phosphopantetheine attachment site binding,molecular_function
74875,GO:0044646,A process in which an organism activates or inhibits the complement system in another organism via the action of a venom.,venom-mediated perturbation of complement activation,biological_process
74876,GO:0044647,"An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.",host-symbiont bicellular tight junction,cellular_component
74877,GO:0044650,"The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.",adhesion of symbiont to host cell,biological_process
74878,GO:0044651,"The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.",adhesion of symbiont to host epithelial cell,biological_process
74879,GO:0044652,"The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.",adhesion of symbiont to host endothelial cell,biological_process
74880,GO:0044655,"Any process that increases the pH of the phagosome, corresponding to a decrease in hydrogen ion concentration, as part of the process of phagosome maturation.",phagosome reneutralization,biological_process
74881,GO:0044656,"Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.",regulation of post-lysosomal vacuole size,biological_process
74882,GO:0044658,"The disruption of host plasma membrane integrity by formation of a pore, resulting in deregulated ion homeostasis, and cellular dysfunction that can result in cell death.",symbiont-mediated pore formation in host plasma membrane,biological_process
74883,GO:0044659,The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm.,viral release from host cell by cytolysis,biological_process
74884,GO:0044660,The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane.,viral release via pore formation in host cell membrane,biological_process
74885,GO:0044663,"A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.",establishment or maintenance of cell type involved in phenotypic switching,biological_process
74886,GO:0044665,"A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.",MLL1/2 complex,cellular_component
74887,GO:0044666,"A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.",MLL3/4 complex,cellular_component
74888,GO:0044667,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).,(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity,molecular_function
74889,GO:0044668,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).,sodium:malonate symporter activity,molecular_function
74890,GO:0044669,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).,sodium:galactoside symporter activity,molecular_function
74891,GO:0044671,"The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).",sorocarp spore cell differentiation,biological_process
74892,GO:0044672,"A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis.",acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex,cellular_component
74893,GO:0044673,"A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.","7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex",cellular_component
74894,GO:0044674,"A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.",methyl coenzyme M reductase complex,cellular_component
74895,GO:0044675,"A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.",formyl-methanofuran dehydrogenase (tungsten enzyme) complex,cellular_component
74896,GO:0044676,"A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.",formyl-methanofuran dehydrogenase (molybdenum enzyme) complex,cellular_component
74897,GO:0044677,A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.,methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex,cellular_component
74898,GO:0044678,"A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.",CoB-CoM heterodisulfide reductase complex,cellular_component
74899,GO:0044679,A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.,methanophenazine reducing hydrogenase complex,cellular_component
74900,GO:0044680,A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis.,methylthiol:coenzyme M methyltransferase complex,cellular_component
74901,GO:0044681,A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.,sulfopyruvate decarboxylase complex,cellular_component
74902,GO:0044682,"Catalysis of the reaction: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.",GTP cyclohydrolase IV activity,molecular_function
74903,GO:0044683,Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.,methylthiol:coenzyme M methyltransferase activity,molecular_function
74904,GO:0044684,"Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + acceptor = 7,8-dihydromethanopterin + reduced acceptor.",dihydromethanopterin reductase activity,molecular_function
74905,GO:0044686,Catalysis of the reaction: O-phospho-L-serine + sulfite + H+ = L-cysteate + phosphate.,cysteate synthase activity,molecular_function
74906,GO:0044687,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.",geranylfarnesyl diphosphate synthase activity,molecular_function
74907,GO:0044688,"Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate or 7,8-dihydroneopterin 2'-phosphate + H+.","7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity",molecular_function
74908,GO:0044689,"Catalysis of the reaction: 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 5'-deoxyadenosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin + H+ + L-methionine + NH4+.","7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity",molecular_function
74909,GO:0044691,The tooth development process in which the teeth enter the mouth and become visible.,tooth eruption,biological_process
74910,GO:0044692,Binds to and increases the activity of an exoribonuclease.,exoribonuclease activator activity,molecular_function
74911,GO:0044693,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).,trehalose:proton symporter activity,molecular_function
74912,GO:0044694,"Entry of a symbiont's genome into a host cell by a pore formed by the symbiont in the host cell. Examples of this process include injection by a non-enveloped virus of the viral genome into the host cytoplasm, usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.",symbiont genome entry into host cell via pore formation in plasma membrane,biological_process
74913,GO:0044695,"An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.",Dsc E3 ubiquitin ligase complex,cellular_component
74914,GO:0044696,"The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells...",killing by virus of host cell by post-segregational killing,biological_process
74915,GO:0044697,"A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.",HICS complex,cellular_component
74916,GO:0044703,"A biological process that directly contributes to the process of producing new individuals, involving another organism.",multi-organism reproductive process,biological_process
74917,GO:0044706,A multicellular organism process which involves another multicellular organism of the same or different species.,multi-multicellular organism process,biological_process
74918,GO:0044715,Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.,8-oxo-dGDP phosphatase activity,molecular_function
74919,GO:0044716,Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.,8-oxo-GDP phosphatase activity,molecular_function
74920,GO:0044717,Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate.,8-hydroxy-dADP phosphatase activity,molecular_function
74921,GO:0044718,"The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.",siderophore transmembrane transport,biological_process
74922,GO:0044719,Any process that modulates the size of an imaginal disc-derived wing.,regulation of imaginal disc-derived wing size,biological_process
74923,GO:0044720,Any process that reduces the size of an imaginal disc-derived wing.,negative regulation of imaginal disc-derived wing size,biological_process
74924,GO:0044721,"The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.","protein import into peroxisome matrix, substrate release",biological_process
74925,GO:0044722,The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.,renal phosphate excretion,biological_process
74926,GO:0044725,"The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.",epigenetic programming in the zygotic pronuclei,biological_process
74927,GO:0044726,"The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.",epigenetic programing of female pronucleus,biological_process
74928,GO:0044727,"The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division.",epigenetic programing of male pronucleus,biological_process
74929,GO:0044729,"Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.",hemi-methylated DNA-binding,molecular_function
74930,GO:0044730,"Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.",bone sialoprotein binding,molecular_function
74931,GO:0044731,A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.,Ost-alpha/Ost-beta complex,cellular_component
74932,GO:0044732,The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.,mitotic spindle pole body,cellular_component
74933,GO:0044733,A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.,venom-mediated perturbation of pH-gated ion channel activity,biological_process
74934,GO:0044734,"A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.",venom-mediated activation of pH-gated ion channel activity,biological_process
74935,GO:0044735,A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.,venom-mediated inhibition of pH-gated ion channel activity,biological_process
74936,GO:0044741,A process in which an organism inhibits or disrupts sensory perception of pain in another organism via the action of a venom.,venom-mediated suppression of sensory perception of pain,biological_process
74937,GO:0044742,"A process in which an organism initiates, promotes, or enhances sensory perception of pain in another organism via the action of a venom. Can manifest as allodynia, a condition that causes pain when a stimulus that normally wouldn't cause pain, or hyperalgesia, an increased sensitivity to feeling pain and an extreme response to pain.",venom-mediated increase of sensory perception of pain,biological_process
74938,GO:0044743,"The directed movement of proteins into an intracellular organelle, across a membrane.",protein transmembrane import into intracellular organelle,biological_process
74939,GO:0044747,Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.,pre-miRNA 3'-end processing,biological_process
74940,GO:0044748,Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.,3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing,molecular_function
74941,GO:0044750,Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity nickel cation transmembrane transporter activity,molecular_function
74942,GO:0044751,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.",cellular response to human chorionic gonadotropin stimulus,biological_process
74943,GO:0044752,"Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.",response to human chorionic gonadotropin,biological_process
74944,GO:0044753,Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.,amphisome,cellular_component
74945,GO:0044754,A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.,autolysosome,cellular_component
74946,GO:0044758,"A process in which a symbiont alters or subverts synaptic transmission, the communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.",symbiont-mediated perturbation of host synaptic transmission,biological_process
74947,GO:0044759,"A process in which a symbiont inhibits or disrupts the normal execution of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.",symbiont-mediated suppression of host synaptic transmission,biological_process
74948,GO:0044760,"A process in which a symbiont alters or subverts cholinergic synaptic transmission, the communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.",symbiont-mediated perturbation of host cholinergic synaptic transmission,biological_process
74949,GO:0044761,"A process in which a symbiont inhibits or disrupts the normal execution of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.",symbiont-mediated suppression of host cholinergic synaptic transmission,biological_process
74950,GO:0044762,A process in which a symbiont inhibits or disrupts the regulated release of a neurotransmitter from a cell in its host organism.,symbiont-mediated suppression of host neurotransmitter secretion,biological_process
74951,GO:0044769,"Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.","ATPase activity, coupled to transmembrane movement of ions, rotational mechanism",molecular_function
74952,GO:0044770,The cell cycle process by which a cell commits to entering the next cell cycle phase.,cell cycle phase transition,biological_process
74953,GO:0044771,The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.,meiotic cell cycle phase transition,biological_process
74954,GO:0044772,The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.,mitotic cell cycle phase transition,biological_process
74955,GO:0044773,A signal transduction process involved in mitotic DNA damage checkpoint.,mitotic DNA damage checkpoint signaling,biological_process
74956,GO:0044774,"A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.",mitotic DNA integrity checkpoint signaling,biological_process
74957,GO:0044775,"A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.","DNA polymerase III, beta sliding clamp processivity factor complex",cellular_component
74958,GO:0044776,"The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.","DNA polymerase III, core complex",cellular_component
74959,GO:0044777,A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.,single-stranded DNA-binding protein complex,cellular_component
74960,GO:0044778,"A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.",meiotic DNA integrity checkpoint signaling,biological_process
74961,GO:0044779,A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.,meiotic spindle checkpoint signaling,biological_process
74962,GO:0044780,"The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.",bacterial-type flagellum assembly,biological_process
74963,GO:0044781,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.",bacterial-type flagellum organization,biological_process
74964,GO:0044782,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.",cilium organization,biological_process
74965,GO:0044784,The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.,metaphase/anaphase transition of cell cycle,biological_process
74966,GO:0044785,The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.,metaphase/anaphase transition of meiotic cell cycle,biological_process
74967,GO:0044786,The DNA-dependent DNA replication that takes place as part of the cell cycle.,cell cycle DNA replication,biological_process
74968,GO:0044787,"The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.",bacterial-type DNA replication,biological_process
74969,GO:0044788,A process in which a host organism alters or subverts a biological process being mediated by a virus with which it is infected.,host-mediated perturbation of viral process,biological_process
74970,GO:0044790,"A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.",suppression of viral release by host,biological_process
74971,GO:0044793,"A process in which a host organism interferes with, inhibits or disrupts a process being mediated by a virus with which it is infected.",host-mediated suppression of viral proces,biological_process
74972,GO:0044794,"A process in which a host organism initiates, promotes, or enhances the normal execution of a biological process being mediated by a virus with which it is infected.",host-mediated activation of viral process,biological_process
74973,GO:0044795,"The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes.",trans-Golgi network to recycling endosome transport,biological_process
74974,GO:0044796,A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.,DNA polymerase processivity factor complex,cellular_component
74975,GO:0044799,"A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG ...",NarGHI complex,cellular_component
74976,GO:0044804,"A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.",nucleophagy,biological_process
74977,GO:0044807,"The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",macrophage migration inhibitory factor production,biological_process
74978,GO:0044808,"The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",oncostatin M production,biological_process
74979,GO:0044809,"The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 17 production,biological_process
74980,GO:0044813,The anaerobic chemical reactions and pathways resulting in the breakdown of pyruvate into butanoate. This pathway is found in strict anaerobes such as Clostridia species.,pyruvate fermentation to butanoate,biological_process
74981,GO:0044816,"A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation.",Nsk1-Dlc1 complex,cellular_component
74982,GO:0044817,The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae.,hydrogen generation via biophotolysis,biological_process
74983,GO:0044818,A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.,mitotic G2/M transition checkpoint,biological_process
74984,GO:0044819,A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.,mitotic G1/S transition checkpoint signaling,biological_process
74985,GO:0044820,"The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.",mitotic telomere tethering at nuclear periphery,biological_process
74986,GO:0044821,"The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.",meiotic telomere tethering at nuclear periphery,biological_process
74987,GO:0044823,"Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.",retroviral integrase activity,molecular_function
74988,GO:0044824,"The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.",retroviral 3' processing activity,molecular_function
74989,GO:0044826,"The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.",viral genome integration into host DNA,biological_process
74990,GO:0044827,A process in which a host organism alters or subverts viral genome replication.,host-mediated perturbation of viral genome replication,biological_process
74991,GO:0044828,"A process in which a host organism interferes with, inhibits or disrupts viral genome replication.",host-mediated suppression of viral genome replication,biological_process
74992,GO:0044829,"A process in which a host organism initiates, promotes, or enhances the normal execution of viral genome replication.",host-mediated activation of viral genome replication,biological_process
74993,GO:0044830,A process in which a host organism alters or subverts viral RNA genome replication.,host-mediated perturbation of viral RNA genome replication,biological_process
74994,GO:0044834,A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome.,retroviral intasome,cellular_component
74995,GO:0044835,The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.,hydrogen generation via nitrogenase,biological_process
74996,GO:0044837,"A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.",actomyosin contractile ring organization,biological_process
74997,GO:0044838,"A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.",cell quiescence,biological_process
74998,GO:0044839,The cell cycle process by which a cell in G2 phase commits to M phase.,cell cycle G2/M phase transition,biological_process
74999,GO:0044840,"A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.",gut granule,cellular_component
75000,GO:0044841,"The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.",gut granule membrane,cellular_component
75001,GO:0044842,"The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.",gut granule lumen,cellular_component
75002,GO:0044843,The cell cycle process by which a cell in G1 phase commits to S phase.,cell cycle G1/S phase transition,biological_process
75003,GO:0044844,"The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.",meiotic interphase II,biological_process
75004,GO:0044847,"The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbion...",iron acquisition from host,biological_process
75005,GO:0044848,A distinct period or stage in a biological process or cycle.,biological phase,biological_process
75006,GO:0044849,"A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.",estrous cycle,biological_process
75007,GO:0044850,A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.,menstrual cycle,biological_process
75008,GO:0044851,"The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.",hair cycle phase,biological_process
75009,GO:0044853,A membrane raft that is part of the plasma membrane.,plasma membrane raft,cellular_component
75010,GO:0044854,"The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.",plasma membrane raft assembly,biological_process
75011,GO:0044855,The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.,plasma membrane raft distribution,biological_process
75012,GO:0044856,"Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.",plasma membrane raft localization,biological_process
75013,GO:0044857,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.",plasma membrane raft organization,biological_process
75014,GO:0044858,The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.,plasma membrane raft polarization,biological_process
75015,GO:0044859,The process in which a protein is incorporated into a plasma membrane raft.,protein insertion into plasma membrane raft,biological_process
75016,GO:0044860,"A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.",protein localization to plasma membrane raft,biological_process
75017,GO:0044861,The directed movement of a protein into a plasma membrane raft.,protein transport into plasma membrane raft,biological_process
75018,GO:0044862,The directed movement of a protein out of a plasma membrane raft.,protein transport out of plasma membrane raft,biological_process
75019,GO:0044865,A process in which a symbiont inhibits or disrupts the normal execution of cell division in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host cell division,biological_process
75020,GO:0044866,"The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.",modulation by host of viral exo-alpha-sialidase activity,biological_process
75021,GO:0044867,The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.,modulation by host of viral catalytic activity,biological_process
75022,GO:0044868,"A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.",modulation by host of viral molecular function,biological_process
75023,GO:0044870,"A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.",modulation by host of viral glycoprotein metabolic process,biological_process
75024,GO:0044871,"A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process.",negative regulation by host of viral glycoprotein metabolic process,biological_process
75025,GO:0044872,"Any process in which a lipoprotein is transported to, or maintained in, a specific location.",lipoprotein localization,biological_process
75026,GO:0044873,"A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.",lipoprotein localization to membrane,biological_process
75027,GO:0044874,"A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.",lipoprotein localization to outer membrane,biological_process
75028,GO:0044875,Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 = gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.,gamma-glutamyl hercynylcysteine sulfoxide synthase activity,molecular_function
75029,GO:0044877,Binding to a macromolecular complex.,protein-containing complex binding,molecular_function
75030,GO:0044878,A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.,mitotic cytokinesis checkpoint signaling,biological_process
75031,GO:0044879,"A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.",mitotic morphogenesis checkpoint signaling,biological_process
75032,GO:0045002,"Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.",double-strand break repair via single-strand annealing,biological_process
75033,GO:0045003,"SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the do...",double-strand break repair via synthesis-dependent strand annealing,biological_process
75034,GO:0045004,Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.,DNA replication proofreading,biological_process
75035,GO:0045005,A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.,DNA-templated DNA replication maintenance of fidelity,biological_process
75036,GO:0045006,The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.,DNA deamination,biological_process
75037,GO:0045007,"The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar.",depurination,biological_process
75038,GO:0045008,"The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.",depyrimidination,biological_process
75039,GO:0045009,An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.,chitosome,cellular_component
75040,GO:0045010,"The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.",actin nucleation,biological_process
75041,GO:0045013,"A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.",carbon catabolite repression of transcription,biological_process
75042,GO:0045014,"A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.",carbon catabolite repression of transcription by glucose,biological_process
75043,GO:0045016,"The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial magnesium ion transmembrane transport,biological_process
75044,GO:0045017,"The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.",glycerolipid biosynthetic process,biological_process
75045,GO:0045018,The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment.,"retrograde transport, vacuole to Golgi",biological_process
75046,GO:0045019,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.",negative regulation of nitric oxide biosynthetic process,biological_process
75047,GO:0045022,"The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes.",early endosome to late endosome transport,biological_process
75048,GO:0045023,"The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.",G0 to G1 transition,biological_process
75049,GO:0045025,"A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.",mitochondrial degradosome,cellular_component
75050,GO:0045027,Binding to DNA ends exposed by the creation of double-strand breaks (DSBs).,DNA end binding,molecular_function
75051,GO:0045028,Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled purinergic nucleotide receptor activity,molecular_function
75052,GO:0045029,"Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.",G protein-coupled UDP receptor activity,molecular_function
75053,GO:0045030,"Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.",G protein-coupled UTP receptor activity,molecular_function
75054,GO:0045031,Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled ATP receptor activity,molecular_function
75055,GO:0045033,"The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.",peroxisome inheritance,biological_process
75056,GO:0045035,"The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).",sensory organ precursor cell division,biological_process
75057,GO:0045036,"The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.",protein targeting to chloroplast,biological_process
75058,GO:0045037,"The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.",protein import into chloroplast stroma,biological_process
75059,GO:0045038,"The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma.",protein import into chloroplast thylakoid membrane,biological_process
75060,GO:0045039,"The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the m...",protein insertion into mitochondrial inner membrane,biological_process
75061,GO:0045040,"The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.",protein insertion into mitochondrial outer membrane,biological_process
75062,GO:0045041,The import of proteins from the cytosol across the outer mitochondrial membrane into the intermembrane space.,protein import into mitochondrial intermembrane space,biological_process
75063,GO:0045046,"The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.",protein import into peroxisome membrane,biological_process
75064,GO:0045047,"The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.",protein targeting to ER,biological_process
75065,GO:0045048,The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.,protein insertion into ER membrane,biological_process
75066,GO:0045049,A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.,protein insertion into ER membrane by N-terminal cleaved signal sequence,biological_process
75067,GO:0045050,A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix.,protein insertion into ER membrane by stop-transfer membrane-anchor sequence,biological_process
75068,GO:0045051,A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences.,protein insertion into ER membrane by internal uncleaved signal-anchor sequence,biological_process
75069,GO:0045053,"The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.",protein retention in Golgi apparatus,biological_process
75070,GO:0045054,"A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.",constitutive secretory pathway,biological_process
75071,GO:0045055,"A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.",regulated exocytosis,biological_process
75072,GO:0045056,The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.,transcytosis,biological_process
75073,GO:0045057,"The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna.",cisternal progression,biological_process
75074,GO:0045058,The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.,T cell selection,biological_process
75075,GO:0045059,The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death.,positive thymic T cell selection,biological_process
75076,GO:0045060,The process of elimination of immature T cells in the thymus which react strongly with self-antigens.,negative thymic T cell selection,biological_process
75077,GO:0045061,The process of T cell selection that occurs in the thymus.,thymic T cell selection,biological_process
75078,GO:0045062,"The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus.",extrathymic T cell selection,biological_process
75079,GO:0045063,"The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.",T-helper 1 cell differentiation,biological_process
75080,GO:0045064,"The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.",T-helper 2 cell differentiation,biological_process
75081,GO:0045065,The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.,cytotoxic T cell differentiation,biological_process
75082,GO:0045066,The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.,regulatory T cell differentiation,biological_process
75083,GO:0045067,The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.,positive extrathymic T cell selection,biological_process
75084,GO:0045068,The process of elimination of extrathymically maturing T cells which react strongly with self-antigens.,negative extrathymic T cell selection,biological_process
75085,GO:0045069,"Any process that modulates the frequency, rate or extent of viral genome replication.",regulation of viral genome replication,biological_process
75086,GO:0045070,"Any process that activates or increases the frequency, rate or extent of viral genome replication.",positive regulation of viral genome replication,biological_process
75087,GO:0045071,"Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.",negative regulation of viral genome replication,biological_process
75088,GO:0045087,Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.,innate immune response,biological_process
75089,GO:0045088,"Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.",regulation of innate immune response,biological_process
75090,GO:0045089,"Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.",positive regulation of innate immune response,biological_process
75091,GO:0045091,"Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.",regulation of single stranded viral RNA replication via double stranded DNA intermediate,biological_process
75092,GO:0045092,A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.,interleukin-18 receptor complex,cellular_component
75093,GO:0045095,"A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.",keratin filament,cellular_component
75094,GO:0045098,"A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments.",type III intermediate filament,cellular_component
75095,GO:0045103,"Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.",intermediate filament-based process,biological_process
75096,GO:0045104,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.",intermediate filament cytoskeleton organization,biological_process
75097,GO:0045105,Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.,intermediate filament polymerization or depolymerization,biological_process
75098,GO:0045106,Disassembly of intermediate filaments by the removal of component monomers from a filament.,intermediate filament depolymerization,biological_process
75099,GO:0045107,Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermedi...,intermediate filament polymerization,biological_process
75100,GO:0045108,"Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.",regulation of intermediate filament polymerization or depolymerization,biological_process
75101,GO:0045109,"Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.",intermediate filament organization,biological_process
75102,GO:0045110,"The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.",intermediate filament bundle assembly,biological_process
75103,GO:0045111,"Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.",intermediate filament cytoskeleton,cellular_component
75104,GO:0045112,"The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.",integrin biosynthetic process,biological_process
75105,GO:0045113,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.",regulation of integrin biosynthetic process,biological_process
75106,GO:0045114,"The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.",beta 2 integrin biosynthetic process,biological_process
75107,GO:0045115,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.",regulation of beta 2 integrin biosynthetic process,biological_process
75108,GO:0045116,Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.,protein neddylation,biological_process
75109,GO:0045117,"The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.",azole transmembrane transport,biological_process
75110,GO:0045119,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances.,azole:proton antiporter activity,molecular_function
75111,GO:0045120,"The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.",pronucleus,cellular_component
75112,GO:0045121,"Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.",membrane raft,cellular_component
75113,GO:0045122,"The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.",aflatoxin biosynthetic process,biological_process
75114,GO:0045123,The migration of a leukocyte from the blood vessels into the surrounding tissue.,cellular extravasation,biological_process
75115,GO:0045124,"Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).",regulation of bone resorption,biological_process
75116,GO:0045125,Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.,bioactive lipid receptor activity,molecular_function
75117,GO:0045127,Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+.,N-acetylglucosamine kinase activity,molecular_function
75118,GO:0045128,"Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.",negative regulation of reciprocal meiotic recombination,biological_process
75119,GO:0045130,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.",keratan sulfotransferase activity,molecular_function
75120,GO:0045131,"Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site.",pre-mRNA branch point binding,molecular_function
75121,GO:0045132,"The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.",meiotic chromosome segregation,biological_process
75122,GO:0045133,"Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.","2,3-dihydroxybenzoate 3,4-dioxygenase activity",molecular_function
75123,GO:0045134,Catalysis of the reaction: UDP + H2O = UMP + phosphate.,UDP phosphatase activity,molecular_function
75124,GO:0045135,Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.,poly(beta-D-mannuronate) lyase activity,molecular_function
75125,GO:0045136,"The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In mammals, examples include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.",development of animal secondary sexual characteristics,biological_process
75126,GO:0045137,"The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.",development of primary sexual characteristics,biological_process
75127,GO:0045138,"The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.",nematode male tail tip morphogenesis,biological_process
75128,GO:0045140,Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol.,inositol phosphoceramide synthase activity,molecular_function
75129,GO:0045141,"The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.",meiotic telomere clustering,biological_process
75130,GO:0045142,"Binding to a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination.",triplex DNA binding,molecular_function
75131,GO:0045143,"The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome ...",homologous chromosome segregation,biological_process
75132,GO:0045144,The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.,meiotic sister chromatid segregation,biological_process
75133,GO:0045145,Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.,single-stranded DNA 5'-3' DNA exonuclease activity,molecular_function
75134,GO:0045148,Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.,tripeptide aminopeptidase activity,molecular_function
75135,GO:0045149,"The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.",acetoin metabolic process,biological_process
75136,GO:0045150,"The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.",acetoin catabolic process,biological_process
75137,GO:0045151,"The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.",acetoin biosynthetic process,biological_process
75138,GO:0045152,"Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.",antisigma factor binding,molecular_function
75139,GO:0045159,"Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.",myosin II binding,molecular_function
75140,GO:0045160,"A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.",myosin I complex,cellular_component
75141,GO:0045161,"The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.",neuronal ion channel clustering,biological_process
75142,GO:0045162,"The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.",clustering of voltage-gated sodium channels,biological_process
75143,GO:0045163,"The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.",clustering of voltage-gated potassium channels,biological_process
75144,GO:0045165,The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.,cell fate commitment,biological_process
75145,GO:0045167,"Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.",asymmetric protein localization involved in cell fate determination,biological_process
75146,GO:0045168,Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.,cell-cell signaling involved in cell fate commitment,biological_process
75147,GO:0045169,"A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.",fusome,cellular_component
75148,GO:0045170,"A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.",spectrosome,cellular_component
75149,GO:0045171,"A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.",intercellular bridge,cellular_component
75150,GO:0045172,"Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.",germline ring canal,cellular_component
75151,GO:0045173,"The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.",O-sialoglycoprotein catabolic process,biological_process
75152,GO:0045174,Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.,glutathione dehydrogenase (ascorbate) activity,molecular_function
75153,GO:0045175,"Any process in which a protein is transported to, or maintained in, basal regions of the cell.",basal protein localization,biological_process
75154,GO:0045176,"Any process in which a protein is transported to, or maintained in, apical regions of the cell.",apical protein localization,biological_process
75155,GO:0045177,"The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.",apical part of cell,cellular_component
75156,GO:0045178,"The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.",basal part of cell,cellular_component
75157,GO:0045179,The region that lies just beneath the plasma membrane on the apical edge of a cell.,apical cortex,cellular_component
75158,GO:0045180,The region that lies just beneath the plasma membrane on the basal edge of a cell.,basal cortex,cellular_component
75159,GO:0045182,"Any molecular function involved in the regulation of initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.",translation regulator activity,molecular_function
75160,GO:0045183,A translation regulator activity that does not involve binding to nucleic acids.,"translation factor activity, non-nucleic acid binding",molecular_function
75161,GO:0045184,The directed movement of a protein to a specific location.,establishment of protein localization,biological_process
75162,GO:0045185,"Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.",maintenance of protein location,biological_process
75163,GO:0045186,"Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.",zonula adherens assembly,biological_process
75164,GO:0045187,"Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.","regulation of circadian sleep/wake cycle, sleep",biological_process
75165,GO:0045188,"Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.","regulation of circadian sleep/wake cycle, non-REM sleep",biological_process
75166,GO:0045190,"The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.",isotype switching,biological_process
75167,GO:0045191,"Any process that modulates the frequency, rate or extent of isotype switching.",regulation of isotype switching,biological_process
75168,GO:0045196,"Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.",establishment or maintenance of neuroblast polarity,biological_process
75169,GO:0045197,"Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.",establishment or maintenance of epithelial cell apical/basal polarity,biological_process
75170,GO:0045198,The specification and formation of the apicobasal polarity of an epithelial cell.,establishment of epithelial cell apical/basal polarity,biological_process
75171,GO:0045199,The maintenance of the apicobasal polarity of an epithelial cell.,maintenance of epithelial cell apical/basal polarity,biological_process
75172,GO:0045200,"The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.",establishment of neuroblast polarity,biological_process
75173,GO:0045201,"The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.",maintenance of neuroblast polarity,biological_process
75174,GO:0045202,"The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane....",synapse,cellular_component
75175,GO:0045211,A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.,postsynaptic membrane,cellular_component
75176,GO:0045214,"The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.",sarcomere organization,biological_process
75177,GO:0045216,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.",cell-cell junction organization,biological_process
75178,GO:0045217,The maintenance of junctions between cells.,cell-cell junction maintenance,biological_process
75179,GO:0045218,"Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.",zonula adherens maintenance,biological_process
75180,GO:0045227,"The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.",capsule polysaccharide biosynthetic process,biological_process
75181,GO:0045228,"The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.",slime layer polysaccharide biosynthetic process,biological_process
75182,GO:0045229,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.",external encapsulating structure organization,biological_process
75183,GO:0045230,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.",capsule organization,biological_process
75184,GO:0045231,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.",slime layer organization,biological_process
75185,GO:0045232,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria.",S-layer organization,biological_process
75186,GO:0045234,The covalent attachment of a palmitoleyl group to a protein.,protein palmitoleylation,biological_process
75187,GO:0045236,Binding to a chemokine receptor in the CXCR family.,CXCR chemokine receptor binding,molecular_function
75188,GO:0045237,Binding to a CXCR1 chemokine receptor.,CXCR1 chemokine receptor binding,molecular_function
75189,GO:0045238,Binding to a CXCR2 chemokine receptor.,CXCR2 chemokine receptor binding,molecular_function
75190,GO:0045239,Any of the heteromeric enzymes that act in the TCA cycle.,tricarboxylic acid cycle heteromeric enzyme complex,cellular_component
75191,GO:0045240,"A multi-enzyme complex that catalyzes the oxidative decarboxylation of an alpha-ketoacid - pyruvate, a branched-chain alpha-ketoacid or alpha-ketoglutarate (also known as 2-oxoglutarate). The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: a dihydrolipoyl transacylase (E2) forms the core of the complex, with an alpha-ketoacid dehydrogenase (E1) and a dihydrolipoamide dehydrogenase (E3) attached through non-covalent bonds. The E1 and E2 components are specific ...",alpha-ketoacid dehydrogenase complex,cellular_component
75192,GO:0045242,Complex that possesses isocitrate dehydrogenase (NAD+) activity.,isocitrate dehydrogenase complex (NAD+),cellular_component
75193,GO:0045244,"A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.",succinate-CoA ligase complex (GDP-forming),cellular_component
75194,GO:0045247,"A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors.",cytosolic electron transfer flavoprotein complex,cellular_component
75195,GO:0045249,A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex,cellular_component
75196,GO:0045251,A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system.,electron transfer flavoprotein complex,cellular_component
75197,GO:0045252,"A multi-enzyme complex that catalyzes the oxidative decarboxylation of alpha-ketoglutarate (also known as 2-oxoglutarate) to form succinyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.",oxoglutarate dehydrogenase complex,cellular_component
75198,GO:0045253,A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,pyruvate dehydrogenase (lipoamide) phosphatase complex,cellular_component
75199,GO:0045254,"A multi-enzyme complex that catalyzes the oxidative decarboxylation of pyruvate to form acetyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: pyruvate dehydrogenase (E1, which may be a homodimer or a heterotetramer of two alpha and two beta subunits, depending on species), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.",pyruvate dehydrogenase complex,cellular_component
75200,GO:0045259,"A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and t...",proton-transporting ATP synthase complex,cellular_component
75201,GO:0045271,"Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.",respiratory chain complex I,cellular_component
75202,GO:0045273,"A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.",respiratory chain complex II (succinate dehydrogenase),cellular_component
75203,GO:0045275,"A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.",respiratory chain complex III,cellular_component
75204,GO:0045277,"A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).",respiratory chain complex IV,cellular_component
75205,GO:0045283,"A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduct...",fumarate reductase complex,cellular_component
75206,GO:0045289,Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.,luciferin monooxygenase activity,molecular_function
75207,GO:0045290,"Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.",D-arabinose 1-dehydrogenase [NAD(P)+] activity,molecular_function
75208,GO:0045291,"The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.","mRNA trans splicing, SL addition",biological_process
75209,GO:0045292,"The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.","mRNA cis splicing, via spliceosome",biological_process
75210,GO:0045293,"A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.",mRNA editing complex,cellular_component
75211,GO:0045294,Binding to catenin complex alpha subunit.,alpha-catenin binding,molecular_function
75212,GO:0045295,Binding to catenin complex gamma subunit.,gamma-catenin binding,molecular_function
75213,GO:0045296,"Binding to cadherin, a type I membrane protein involved in cell adhesion.",cadherin binding,molecular_function
75214,GO:0045298,A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.,tubulin complex,cellular_component
75215,GO:0045299,The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.,otolith mineralization,biological_process
75216,GO:0045300,Catalysis of the reaction: 2 H+ + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin].,stearoyl-[ACP] desaturase activity,molecular_function
75217,GO:0045301,Catalysis of the reaction: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + acceptor-H2 + O2 = N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA + acceptor + H2O.,tRNA 2-(methylsulfanyl)-N(6)-isopentenyladenosine(37) hydroxylase activity,molecular_function
75218,GO:0045302,"Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.",choloylglycine hydrolase activity,molecular_function
75219,GO:0045303,"Catalysis of the reaction: L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.","L-2,4-diaminobutyrate:2-oxoglutarate transaminase activity",molecular_function
75220,GO:0045304,"Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.",regulation of establishment of competence for transformation,biological_process
75221,GO:0045309,Binding to a phosphorylated amino acid residue within a protein.,protein phosphorylated amino acid binding,molecular_function
75222,GO:0045311,The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.,invasive growth in response to pheromone,biological_process
75223,GO:0045312,"The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",nor-spermidine biosynthetic process,biological_process
75224,GO:0045313,"A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.",rhabdomere membrane biogenesis,biological_process
75225,GO:0045314,"Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.",regulation of compound eye photoreceptor development,biological_process
75226,GO:0045315,"Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.",positive regulation of compound eye photoreceptor development,biological_process
75227,GO:0045316,"Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.",negative regulation of compound eye photoreceptor development,biological_process
75228,GO:0045317,"The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.",equator specification,biological_process
75229,GO:0045321,"A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.",leukocyte activation,biological_process
75230,GO:0045322,Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters.,unmethylated CpG binding,molecular_function
75231,GO:0045323,A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.,interleukin-1 receptor complex,cellular_component
75232,GO:0045324,"The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.",late endosome to vacuole transport,biological_process
75233,GO:0045329,"The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.",carnitine biosynthetic process,biological_process
75234,GO:0045332,The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.,phospholipid translocation,biological_process
75235,GO:0045333,The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).,cellular respiration,biological_process
75236,GO:0045334,"A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.",clathrin-coated endocytic vesicle,cellular_component
75237,GO:0045335,A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.,phagocytic vesicle,cellular_component
75238,GO:0045336,"A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.",clathrin-coated phagocytic vesicle,cellular_component
75239,GO:0045337,"The chemical reactions and pathways resulting in the formation of 2-trans,6-trans-farnesyl diphosphate from prenyl diphosphate.","trans, trans-farnesyl diphosphate biosynthetic process",biological_process
75240,GO:0045338,"The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.",farnesyl diphosphate metabolic process,biological_process
75241,GO:0045339,The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.,farnesyl diphosphate catabolic process,biological_process
75242,GO:0045340,Binding to a mercury ion (Hg2+).,mercury ion binding,molecular_function
75243,GO:0045341,The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.,MHC class I biosynthetic process,biological_process
75244,GO:0045342,The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.,MHC class II biosynthetic process,biological_process
75245,GO:0045343,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.",regulation of MHC class I biosynthetic process,biological_process
75246,GO:0045344,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.",negative regulation of MHC class I biosynthetic process,biological_process
75247,GO:0045345,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.",positive regulation of MHC class I biosynthetic process,biological_process
75248,GO:0045346,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.",regulation of MHC class II biosynthetic process,biological_process
75249,GO:0045347,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.",negative regulation of MHC class II biosynthetic process,biological_process
75250,GO:0045348,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.",positive regulation of MHC class II biosynthetic process,biological_process
75251,GO:0045352,Blocks the binding of interleukin-1 to interleukin-1 type I receptors.,interleukin-1 type I receptor antagonist activity,molecular_function
75252,GO:0045353,Blocks the binding of interleukin-1 to interleukin-1 type II receptors.,interleukin-1 type II receptor antagonist activity,molecular_function
75253,GO:0045428,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.",regulation of nitric oxide biosynthetic process,biological_process
75254,GO:0045429,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.",positive regulation of nitric oxide biosynthetic process,biological_process
75255,GO:0045430,Catalysis of the reaction: a chalcone = a flavanone.,chalcone isomerase activity,molecular_function
75256,GO:0045431,Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.,flavonol synthase activity,molecular_function
75257,GO:0045433,The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.,"male courtship behavior, veined wing generated song production",biological_process
75258,GO:0045434,"Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.","negative regulation of female receptivity, post-mating",biological_process
75259,GO:0045435,"Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).",lycopene epsilon cyclase activity,molecular_function
75260,GO:0045436,"Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.",lycopene beta cyclase activity,molecular_function
75261,GO:0045437,Catalysis of the reaction: H2O + uridine = ribofuranose + uracil.,uridine nucleosidase activity,molecular_function
75262,GO:0045439,Catalysis of the reaction: isopenicillin N = penicillin N.,isopenicillin-N epimerase activity,molecular_function
75263,GO:0045442,Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate.,deacetoxycephalosporin-C hydroxylase activity,molecular_function
75264,GO:0045443,"The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.",juvenile hormone secretion,biological_process
75265,GO:0045444,"The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.",fat cell differentiation,biological_process
75266,GO:0045445,"The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.",myoblast differentiation,biological_process
75267,GO:0045446,"The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.",endothelial cell differentiation,biological_process
75268,GO:0045448,"The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.","mitotic cell cycle, embryonic",biological_process
75269,GO:0045450,Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.,bicoid mRNA localization,biological_process
75270,GO:0045451,"Any process in which oskar mRNA is transported to, or maintained in, the germ plasm.",germ plasm oskar mRNA localization,biological_process
75271,GO:0045453,"The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.",bone resorption,biological_process
75272,GO:0045454,Any process that maintains the redox environment of a cell or compartment within a cell.,cell redox homeostasis,biological_process
75273,GO:0045455,"The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.",ecdysteroid metabolic process,biological_process
75274,GO:0045456,"The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.",ecdysteroid biosynthetic process,biological_process
75275,GO:0045457,"The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.",ecdysteroid secretion,biological_process
75276,GO:0045458,Genetic recombination within the DNA of the genes coding for ribosomal RNA.,recombination within rDNA repeats,biological_process
75277,GO:0045460,"The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.",sterigmatocystin metabolic process,biological_process
75278,GO:0045461,"The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.",sterigmatocystin biosynthetic process,biological_process
75279,GO:0045462,Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.,trichothecene 3-O-acetyltransferase activity,molecular_function
75280,GO:0045463,"The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.",R8 cell development,biological_process
75281,GO:0045464,"The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",R8 cell fate specification,biological_process
75282,GO:0045465,The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.,R8 cell differentiation,biological_process
75283,GO:0045466,The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.,R7 cell differentiation,biological_process
75284,GO:0045467,"The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.",R7 cell development,biological_process
75285,GO:0045468,Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.,regulation of R8 cell spacing in compound eye,biological_process
75286,GO:0045469,Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.,negative regulation of R8 cell spacing in compound eye,biological_process
75287,GO:0045470,The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.,R8 cell-mediated photoreceptor organization,biological_process
75288,GO:0045471,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.",response to ethanol,biological_process
75289,GO:0045472,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.",response to ether,biological_process
75290,GO:0045475,The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.,locomotor rhythm,biological_process
75291,GO:0045476,"Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.",nurse cell apoptotic process,biological_process
75292,GO:0045477,"Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.",regulation of nurse cell apoptotic process,biological_process
75293,GO:0045478,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.",fusome organization,biological_process
75294,GO:0045480,Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + H2O2.,galactose oxidase activity,molecular_function
75295,GO:0045481,Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.,6-endo-hydroxycineole dehydrogenase activity,molecular_function
75296,GO:0045482,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.",trichodiene synthase activity,molecular_function
75297,GO:0045483,"Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.",aristolochene synthase activity,molecular_function
75298,GO:0045484,Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.,L-lysine:2-oxoglutarate 6-transaminase activity,molecular_function
75299,GO:0045485,Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.,omega-6 fatty acid desaturase activity,molecular_function
75300,GO:0045486,"Catalysis of the reaction: 2-oxoglutarate + a (2S)-flavan-4-one + O2 = a (2R,3R)-dihydroflavonol + CO2 + succinate.",flavanone 3-dioxygenase activity,molecular_function
75301,GO:0045487,The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.,gibberellin catabolic process,biological_process
75302,GO:0045488,"The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.",pectin metabolic process,biological_process
75303,GO:0045489,"The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.",pectin biosynthetic process,biological_process
75304,GO:0045490,"The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.",pectin catabolic process,biological_process
75305,GO:0045491,"The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.",xylan metabolic process,biological_process
75306,GO:0045492,"The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.",xylan biosynthetic process,biological_process
75307,GO:0045493,"The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.",xylan catabolic process,biological_process
75308,GO:0045494,"Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.",photoreceptor cell maintenance,biological_process
75309,GO:0045496,"The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.",male analia development,biological_process
75310,GO:0045497,"The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.",female analia development,biological_process
75311,GO:0045498,"The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.",sex comb development,biological_process
75312,GO:0045499,Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.,chemorepellent activity,molecular_function
75313,GO:0045500,"The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",sevenless signaling pathway,biological_process
75314,GO:0045501,"Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.",regulation of sevenless signaling pathway,biological_process
75315,GO:0045503,Binding to a light chain of the dynein complex.,dynein light chain binding,molecular_function
75316,GO:0045504,Binding to a heavy chain of the dynein complex.,dynein heavy chain binding,molecular_function
75317,GO:0045505,Binding to an intermediate chain of the dynein complex.,dynein intermediate chain binding,molecular_function
75318,GO:0045506,Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-24 receptor activity,molecular_function
75319,GO:0045507,Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-25 receptor activity,molecular_function
75320,GO:0045508,Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-26 receptor activity,molecular_function
75321,GO:0045509,Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-27 receptor activity,molecular_function
75322,GO:0045510,Binding to interleukin-24.,interleukin-24 binding,molecular_function
75323,GO:0045511,Binding to interleukin-25.,interleukin-25 binding,molecular_function
75324,GO:0045512,Binding to interleukin-26.,interleukin-26 binding,molecular_function
75325,GO:0045513,Binding to interleukin-27.,interleukin-27 binding,molecular_function
75326,GO:0045514,Binding to an interleukin-16 receptor.,interleukin-16 receptor binding,molecular_function
75327,GO:0045515,Binding to an interleukin-18 receptor.,interleukin-18 receptor binding,molecular_function
75328,GO:0045516,Binding to an interleukin-19 receptor.,interleukin-19 receptor binding,molecular_function
75329,GO:0045517,Binding to an interleukin-20 receptor.,interleukin-20 receptor binding,molecular_function
75330,GO:0045518,Binding to an interleukin-22 receptor.,interleukin-22 receptor binding,molecular_function
75331,GO:0045519,Binding to an interleukin-23 receptor.,interleukin-23 receptor binding,molecular_function
75332,GO:0045520,Binding to an interleukin-24 receptor.,interleukin-24 receptor binding,molecular_function
75333,GO:0045521,Binding to an interleukin-25 receptor.,interleukin-25 receptor binding,molecular_function
75334,GO:0045522,Binding to an interleukin-26 receptor.,interleukin-26 receptor binding,molecular_function
75335,GO:0045523,Binding to an interleukin-27 receptor.,interleukin-27 receptor binding,molecular_function
75336,GO:0045540,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.",regulation of cholesterol biosynthetic process,biological_process
75337,GO:0045541,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.",negative regulation of cholesterol biosynthetic process,biological_process
75338,GO:0045542,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.",positive regulation of cholesterol biosynthetic process,biological_process
75339,GO:0045543,Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.,gibberellin 2-beta-dioxygenase activity,molecular_function
75340,GO:0045544,"Catalysis of the reaction: 2 2-oxoglutarate + gibberellin A12 (GA12) + H+ + 3 O2 = 3 CO2 + gibberellin A9 (GA9) + 2 H2O + 2 succinate. This reaction results in the oxidation of C-20 gibberellins to form the corresponding C-19 lactones, via a three-step oxidation at C-20 of the GA skeleton. Also converts GA53 to GA20. GA25 is also formed as a minor product.",gibberellin 20-oxidase activity,molecular_function
75341,GO:0045545,"Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.",syndecan binding,molecular_function
75342,GO:0045547,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.","ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity",molecular_function
75343,GO:0045548,Catalysis of the reaction: L-phenylalanine = NH4 + trans-cinnamate.,phenylalanine ammonia-lyase activity,molecular_function
75344,GO:0045549,"Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.",9-cis-epoxycarotenoid dioxygenase activity,molecular_function
75345,GO:0045551,"Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+. Also acts on coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol.",cinnamyl-alcohol dehydrogenase activity,molecular_function
75346,GO:0045552,"Catalysis of the reaction: a (2R,3S,4S)-leucoanthocyanidin + NADP+ = a (2R,3R)-dihydroflavonol + NADPH + H+.",dihydroflavanol 4-reductase activity,molecular_function
75347,GO:0045569,"Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.",TRAIL binding,molecular_function
75348,GO:0045570,"Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.",regulation of imaginal disc growth,biological_process
75349,GO:0045571,"Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.",negative regulation of imaginal disc growth,biological_process
75350,GO:0045572,"Any process that activates or increases the frequency, rate or extent of imaginal disc growth.",positive regulation of imaginal disc growth,biological_process
75351,GO:0045574,"The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.",sterigmatocystin catabolic process,biological_process
75352,GO:0045575,"The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.",basophil activation,biological_process
75353,GO:0045576,"The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.",mast cell activation,biological_process
75354,GO:0045577,"Any process that modulates the frequency, rate or extent of B cell differentiation.",regulation of B cell differentiation,biological_process
75355,GO:0045578,"Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.",negative regulation of B cell differentiation,biological_process
75356,GO:0045579,"Any process that activates or increases the frequency, rate or extent of B cell differentiation.",positive regulation of B cell differentiation,biological_process
75357,GO:0045580,"Any process that modulates the frequency, rate or extent of T cell differentiation.",regulation of T cell differentiation,biological_process
75358,GO:0045581,"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.",negative regulation of T cell differentiation,biological_process
75359,GO:0045582,"Any process that activates or increases the frequency, rate or extent of T cell differentiation.",positive regulation of T cell differentiation,biological_process
75360,GO:0045583,"Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation.",regulation of cytotoxic T cell differentiation,biological_process
75361,GO:0045584,"Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.",negative regulation of cytotoxic T cell differentiation,biological_process
75362,GO:0045585,"Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.",positive regulation of cytotoxic T cell differentiation,biological_process
75363,GO:0045586,"Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.",regulation of gamma-delta T cell differentiation,biological_process
75364,GO:0045587,"Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.",negative regulation of gamma-delta T cell differentiation,biological_process
75365,GO:0045588,"Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.",positive regulation of gamma-delta T cell differentiation,biological_process
75366,GO:0045589,"Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.",regulation of regulatory T cell differentiation,biological_process
75367,GO:0045590,"Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.",negative regulation of regulatory T cell differentiation,biological_process
75368,GO:0045591,"Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.",positive regulation of regulatory T cell differentiation,biological_process
75369,GO:0045592,"Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.",regulation of cumulus cell differentiation,biological_process
75370,GO:0045593,"Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.",negative regulation of cumulus cell differentiation,biological_process
75371,GO:0045594,"Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.",positive regulation of cumulus cell differentiation,biological_process
75372,GO:0045595,"Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.",regulation of cell differentiation,biological_process
75373,GO:0045596,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.",negative regulation of cell differentiation,biological_process
75374,GO:0045597,"Any process that activates or increases the frequency, rate or extent of cell differentiation.",positive regulation of cell differentiation,biological_process
75375,GO:0045598,"Any process that modulates the frequency, rate or extent of adipocyte differentiation.",regulation of fat cell differentiation,biological_process
75376,GO:0045599,"Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.",negative regulation of fat cell differentiation,biological_process
75377,GO:0045600,"Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.",positive regulation of fat cell differentiation,biological_process
75378,GO:0045601,"Any process that modulates the frequency, rate or extent of endothelial cell differentiation.",regulation of endothelial cell differentiation,biological_process
75379,GO:0045602,"Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.",negative regulation of endothelial cell differentiation,biological_process
75380,GO:0045603,"Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.",positive regulation of endothelial cell differentiation,biological_process
75381,GO:0045604,"Any process that modulates the frequency, rate or extent of epidermal cell differentiation.",regulation of epidermal cell differentiation,biological_process
75382,GO:0045605,"Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.",negative regulation of epidermal cell differentiation,biological_process
75383,GO:0045606,"Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.",positive regulation of epidermal cell differentiation,biological_process
75384,GO:0045607,"Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.",regulation of inner ear auditory receptor cell differentiation,biological_process
75385,GO:0045608,"Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.",negative regulation of inner ear auditory receptor cell differentiation,biological_process
75386,GO:0045609,"Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.",positive regulation of inner ear auditory receptor cell differentiation,biological_process
75387,GO:0045610,"Any process that modulates the frequency, rate or extent of hemocyte differentiation.",regulation of hemocyte differentiation,biological_process
75388,GO:0045611,"Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.",negative regulation of hemocyte differentiation,biological_process
75389,GO:0045612,"Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.",positive regulation of hemocyte differentiation,biological_process
75390,GO:0045613,"Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.",regulation of plasmatocyte differentiation,biological_process
75391,GO:0045614,"Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.",negative regulation of plasmatocyte differentiation,biological_process
75392,GO:0045615,"Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.",positive regulation of plasmatocyte differentiation,biological_process
75393,GO:0045616,"Any process that modulates the frequency, rate or extent of keratinocyte differentiation.",regulation of keratinocyte differentiation,biological_process
75394,GO:0045617,"Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.",negative regulation of keratinocyte differentiation,biological_process
75395,GO:0045618,"Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.",positive regulation of keratinocyte differentiation,biological_process
75396,GO:0045619,"Any process that modulates the frequency, rate or extent of lymphocyte differentiation.",regulation of lymphocyte differentiation,biological_process
75397,GO:0045620,"Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.",negative regulation of lymphocyte differentiation,biological_process
75398,GO:0045621,"Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.",positive regulation of lymphocyte differentiation,biological_process
75399,GO:0045622,"Any process that modulates the frequency, rate or extent of T-helper cell differentiation.",regulation of T-helper cell differentiation,biological_process
75400,GO:0045623,"Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.",negative regulation of T-helper cell differentiation,biological_process
75401,GO:0045624,"Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.",positive regulation of T-helper cell differentiation,biological_process
75402,GO:0045625,"Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.",regulation of T-helper 1 cell differentiation,biological_process
75403,GO:0045626,"Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.",negative regulation of T-helper 1 cell differentiation,biological_process
75404,GO:0045627,"Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.",positive regulation of T-helper 1 cell differentiation,biological_process
75405,GO:0045628,"Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation.",regulation of T-helper 2 cell differentiation,biological_process
75406,GO:0045629,"Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.",negative regulation of T-helper 2 cell differentiation,biological_process
75407,GO:0045630,"Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.",positive regulation of T-helper 2 cell differentiation,biological_process
75408,GO:0045631,"Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.",regulation of mechanoreceptor differentiation,biological_process
75409,GO:0045632,"Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.",negative regulation of mechanoreceptor differentiation,biological_process
75410,GO:0045633,"Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.",positive regulation of mechanoreceptor differentiation,biological_process
75411,GO:0045634,"Any process that modulates the frequency, rate or extent of melanocyte differentiation.",regulation of melanocyte differentiation,biological_process
75412,GO:0045635,"Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.",negative regulation of melanocyte differentiation,biological_process
75413,GO:0045636,"Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.",positive regulation of melanocyte differentiation,biological_process
75414,GO:0045637,"Any process that modulates the frequency, rate or extent of myeloid cell differentiation.",regulation of myeloid cell differentiation,biological_process
75415,GO:0045638,"Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.",negative regulation of myeloid cell differentiation,biological_process
75416,GO:0045639,"Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.",positive regulation of myeloid cell differentiation,biological_process
75417,GO:0045640,"Any process that modulates the frequency, rate or extent of basophil differentiation.",regulation of basophil differentiation,biological_process
75418,GO:0045641,"Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.",negative regulation of basophil differentiation,biological_process
75419,GO:0045642,"Any process that activates or increases the frequency, rate or extent of basophil differentiation.",positive regulation of basophil differentiation,biological_process
75420,GO:0045643,"Any process that modulates the frequency, rate or extent of eosinophil differentiation.",regulation of eosinophil differentiation,biological_process
75421,GO:0045644,"Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.",negative regulation of eosinophil differentiation,biological_process
75422,GO:0045645,"Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.",positive regulation of eosinophil differentiation,biological_process
75423,GO:0045646,"Any process that modulates the frequency, rate or extent of erythrocyte differentiation.",regulation of erythrocyte differentiation,biological_process
75424,GO:0045647,"Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.",negative regulation of erythrocyte differentiation,biological_process
75425,GO:0045648,"Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.",positive regulation of erythrocyte differentiation,biological_process
75426,GO:0045649,"Any process that modulates the frequency, rate or extent of macrophage differentiation.",regulation of macrophage differentiation,biological_process
75427,GO:0045650,"Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.",negative regulation of macrophage differentiation,biological_process
75428,GO:0045651,"Any process that activates or increases the frequency, rate or extent of macrophage differentiation.",positive regulation of macrophage differentiation,biological_process
75429,GO:0045652,"Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.",regulation of megakaryocyte differentiation,biological_process
75430,GO:0045653,"Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.",negative regulation of megakaryocyte differentiation,biological_process
75431,GO:0045654,"Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.",positive regulation of megakaryocyte differentiation,biological_process
75432,GO:0045655,"Any process that modulates the frequency, rate or extent of monocyte differentiation.",regulation of monocyte differentiation,biological_process
75433,GO:0045656,"Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.",negative regulation of monocyte differentiation,biological_process
75434,GO:0045657,"Any process that activates or increases the frequency, rate or extent of monocyte differentiation.",positive regulation of monocyte differentiation,biological_process
75435,GO:0045658,"Any process that modulates the frequency, rate or extent of neutrophil differentiation.",regulation of neutrophil differentiation,biological_process
75436,GO:0045659,"Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.",negative regulation of neutrophil differentiation,biological_process
75437,GO:0045660,"Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.",positive regulation of neutrophil differentiation,biological_process
75438,GO:0045661,"Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",regulation of myoblast differentiation,biological_process
75439,GO:0045662,"Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",negative regulation of myoblast differentiation,biological_process
75440,GO:0045663,"Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",positive regulation of myoblast differentiation,biological_process
75441,GO:0045664,"Any process that modulates the frequency, rate or extent of neuron differentiation.",regulation of neuron differentiation,biological_process
75442,GO:0045665,"Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.",negative regulation of neuron differentiation,biological_process
75443,GO:0045666,"Any process that activates or increases the frequency, rate or extent of neuron differentiation.",positive regulation of neuron differentiation,biological_process
75444,GO:0045667,"Any process that modulates the frequency, rate or extent of osteoblast differentiation.",regulation of osteoblast differentiation,biological_process
75445,GO:0045668,"Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.",negative regulation of osteoblast differentiation,biological_process
75446,GO:0045669,"Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.",positive regulation of osteoblast differentiation,biological_process
75447,GO:0045670,"Any process that modulates the frequency, rate or extent of osteoclast differentiation.",regulation of osteoclast differentiation,biological_process
75448,GO:0045671,"Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.",negative regulation of osteoclast differentiation,biological_process
75449,GO:0045672,"Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.",positive regulation of osteoclast differentiation,biological_process
75450,GO:0045676,"Any process that modulates the frequency, rate or extent of R7 differentiation.",regulation of R7 cell differentiation,biological_process
75451,GO:0045677,"Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.",negative regulation of R7 cell differentiation,biological_process
75452,GO:0045678,"Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.",positive regulation of R7 cell differentiation,biological_process
75453,GO:0045679,"Any process that modulates the frequency, rate or extent of R8 differentiation.",regulation of R8 cell differentiation,biological_process
75454,GO:0045680,"Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation.",negative regulation of R8 cell differentiation,biological_process
75455,GO:0045681,"Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.",positive regulation of R8 cell differentiation,biological_process
75456,GO:0045682,"Any process that modulates the frequency, rate or extent of epidermis development.",regulation of epidermis development,biological_process
75457,GO:0045683,"Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.",negative regulation of epidermis development,biological_process
75458,GO:0045684,"Any process that activates or increases the frequency, rate or extent of epidermis development.",positive regulation of epidermis development,biological_process
75459,GO:0045685,"Any process that modulates the frequency, rate or extent of glia cell differentiation.",regulation of glial cell differentiation,biological_process
75460,GO:0045686,"Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.",negative regulation of glial cell differentiation,biological_process
75461,GO:0045687,"Any process that activates or increases the frequency, rate or extent of glia cell differentiation.",positive regulation of glial cell differentiation,biological_process
75462,GO:0045688,"Any process that modulates the frequency, rate or extent of antipodal cell differentiation.",regulation of antipodal cell differentiation,biological_process
75463,GO:0045689,"Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.",negative regulation of antipodal cell differentiation,biological_process
75464,GO:0045690,"Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation.",positive regulation of antipodal cell differentiation,biological_process
75465,GO:0045691,"Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation.",regulation of embryo sac central cell differentiation,biological_process
75466,GO:0045692,"Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation.",negative regulation of embryo sac central cell differentiation,biological_process
75467,GO:0045693,"Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.",positive regulation of embryo sac central cell differentiation,biological_process
75468,GO:0045694,"Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation.",regulation of embryo sac egg cell differentiation,biological_process
75469,GO:0045695,"Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.",negative regulation of embryo sac egg cell differentiation,biological_process
75470,GO:0045696,"Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.",positive regulation of embryo sac egg cell differentiation,biological_process
75471,GO:0045697,"Any process that modulates the frequency, rate or extent of synergid cell differentiation.",regulation of synergid differentiation,biological_process
75472,GO:0045698,"Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation.",negative regulation of synergid differentiation,biological_process
75473,GO:0045699,"Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.",positive regulation of synergid differentiation,biological_process
75474,GO:0045700,"Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.",regulation of spermatid nuclear differentiation,biological_process
75475,GO:0045701,"Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.",negative regulation of spermatid nuclear differentiation,biological_process
75476,GO:0045702,"Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.",positive regulation of spermatid nuclear differentiation,biological_process
75477,GO:0045703,Catalysis of the reduction of a ketone group to form the corresponding alcohol.,ketoreductase activity,molecular_function
75478,GO:0045704,"Any process that modulates the frequency, rate or extent of salivary gland determination.",regulation of salivary gland boundary specification,biological_process
75479,GO:0045705,"Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.",negative regulation of salivary gland boundary specification,biological_process
75480,GO:0045706,"Any process that activates or increases the frequency, rate or extent of salivary gland determination.",positive regulation of salivary gland boundary specification,biological_process
75481,GO:0045707,"Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism.",regulation of adult salivary gland boundary specification,biological_process
75482,GO:0045708,"Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism.",regulation of larval salivary gland boundary specification,biological_process
75483,GO:0045709,"Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.",negative regulation of adult salivary gland boundary specification,biological_process
75484,GO:0045710,"Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.",negative regulation of larval salivary gland boundary specification,biological_process
75485,GO:0045711,"Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.",positive regulation of adult salivary gland boundary specification,biological_process
75486,GO:0045712,"Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism.",positive regulation of larval salivary gland boundary specification,biological_process
75487,GO:0045717,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.",negative regulation of fatty acid biosynthetic process,biological_process
75488,GO:0045719,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.",negative regulation of glycogen biosynthetic process,biological_process
75489,GO:0045720,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.",negative regulation of integrin biosynthetic process,biological_process
75490,GO:0045721,"Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.",negative regulation of gluconeogenesis,biological_process
75491,GO:0045722,"Any process that activates or increases the frequency, rate or extent of gluconeogenesis.",positive regulation of gluconeogenesis,biological_process
75492,GO:0045723,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.",positive regulation of fatty acid biosynthetic process,biological_process
75493,GO:0045724,"Any process that activates or increases the frequency, rate or extent of the formation of a cilium.",positive regulation of cilium assembly,biological_process
75494,GO:0045725,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.",positive regulation of glycogen biosynthetic process,biological_process
75495,GO:0045726,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.",positive regulation of integrin biosynthetic process,biological_process
75496,GO:0045727,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.",positive regulation of translation,biological_process
75497,GO:0045728,"A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.",respiratory burst after phagocytosis,biological_process
75498,GO:0045729,"The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.",respiratory burst at fertilization,biological_process
75499,GO:0045730,"A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",respiratory burst,biological_process
75500,GO:0045732,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.",positive regulation of protein catabolic process,biological_process
75501,GO:0045733,"The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.",acetate catabolic process,biological_process
75502,GO:0045734,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.",regulation of acetate catabolic process,biological_process
75503,GO:0045735,Functions in the storage of nutritious substrates.,nutrient reservoir activity,molecular_function
75504,GO:0045736,"Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.",negative regulation of cyclin-dependent protein serine/threonine kinase activity,biological_process
75505,GO:0045737,"Any process that activates or increases the frequency, rate or extent of CDK activity.",positive regulation of cyclin-dependent protein serine/threonine kinase activity,biological_process
75506,GO:0045738,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.",negative regulation of DNA repair,biological_process
75507,GO:0045739,"Any process that activates or increases the frequency, rate or extent of DNA repair.",positive regulation of DNA repair,biological_process
75508,GO:0045740,"Any process that activates or increases the frequency, rate or extent of DNA replication.",positive regulation of DNA replication,biological_process
75509,GO:0045742,"Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.",positive regulation of epidermal growth factor receptor signaling pathway,biological_process
75510,GO:0045743,"Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.",positive regulation of fibroblast growth factor receptor signaling pathway,biological_process
75511,GO:0045744,"Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.",negative regulation of G protein-coupled receptor signaling pathway,biological_process
75512,GO:0045745,"Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.",positive regulation of G protein-coupled receptor signaling pathway,biological_process
75513,GO:0045746,"Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.",negative regulation of Notch signaling pathway,biological_process
75514,GO:0045747,"Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.",positive regulation of Notch signaling pathway,biological_process
75515,GO:0045748,Any process that activates or enforces the correct R8 cell spacing in a compound eye.,positive regulation of R8 cell spacing in compound eye,biological_process
75516,GO:0045751,"Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.",negative regulation of Toll signaling pathway,biological_process
75517,GO:0045752,"Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.",positive regulation of Toll signaling pathway,biological_process
75518,GO:0045753,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.",negative regulation of acetate catabolic process,biological_process
75519,GO:0045754,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.",positive regulation of acetate catabolic process,biological_process
75520,GO:0045759,"Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",negative regulation of action potential,biological_process
75521,GO:0045760,"Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",positive regulation of action potential,biological_process
75522,GO:0045761,"Any process that modulates the frequency, rate or extent of adenylate cyclase activity.",regulation of adenylate cyclase activity,biological_process
75523,GO:0045762,"Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.",positive regulation of adenylate cyclase activity,biological_process
75524,GO:0045763,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.",negative regulation of amino acid metabolic process,biological_process
75525,GO:0045764,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.",positive regulation of amino acid metabolic process,biological_process
75526,GO:0045765,"Any process that modulates the frequency, rate or extent of angiogenesis.",regulation of angiogenesis,biological_process
75527,GO:0045766,Any process that activates or increases angiogenesis.,positive regulation of angiogenesis,biological_process
75528,GO:0045769,"Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.",negative regulation of asymmetric cell division,biological_process
75529,GO:0045770,"Any process that activates or increases the frequency, rate or extent of asymmetric cell division.",positive regulation of asymmetric cell division,biological_process
75530,GO:0045771,Any process that reduces autophagosome size.,negative regulation of autophagosome size,biological_process
75531,GO:0045772,Any process that increases autophagosome size.,positive regulation of autophagosome size,biological_process
75532,GO:0045773,"Any process that activates or increases the frequency, rate or extent of axon extension.",positive regulation of axon extension,biological_process
75533,GO:0045774,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.",negative regulation of beta 2 integrin biosynthetic process,biological_process
75534,GO:0045775,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.",positive regulation of beta 2 integrin biosynthetic process,biological_process
75535,GO:0045776,Any process in which the force of blood traveling through the circulatory system is decreased.,negative regulation of blood pressure,biological_process
75536,GO:0045777,Any process in which the force of blood traveling through the circulatory system is increased.,positive regulation of blood pressure,biological_process
75537,GO:0045778,"Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.",positive regulation of ossification,biological_process
75538,GO:0045779,"Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.",negative regulation of bone resorption,biological_process
75539,GO:0045780,"Any process that activates or increases the frequency, rate or extent of bone resorption.",positive regulation of bone resorption,biological_process
75540,GO:0045781,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.",negative regulation of cell budding,biological_process
75541,GO:0045782,"Any process that activates or increases the frequency, rate or extent of cell budding.",positive regulation of cell budding,biological_process
75542,GO:0045785,"Any process that activates or increases the frequency, rate or extent of cell adhesion.",positive regulation of cell adhesion,biological_process
75543,GO:0045786,"Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.",negative regulation of cell cycle,biological_process
75544,GO:0045787,Any process that activates or increases the rate or extent of progression through the cell cycle.,positive regulation of cell cycle,biological_process
75545,GO:0045792,Any process that reduces cell size.,negative regulation of cell size,biological_process
75546,GO:0045793,Any process that increases cell size.,positive regulation of cell size,biological_process
75547,GO:0045794,Any process that decreases cell volume.,negative regulation of cell volume,biological_process
75548,GO:0045795,Any process that increases cell volume.,positive regulation of cell volume,biological_process
75549,GO:0045796,"Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.",negative regulation of intestinal cholesterol absorption,biological_process
75550,GO:0045797,"Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.",positive regulation of intestinal cholesterol absorption,biological_process
75551,GO:0045800,"Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.",negative regulation of chitin-based cuticle tanning,biological_process
75552,GO:0045801,"Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning.",positive regulation of chitin-based cuticle tanning,biological_process
75553,GO:0045804,"Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.",negative regulation of eclosion,biological_process
75554,GO:0045805,"Any process that activates or increases the frequency, rate or extent of eclosion.",positive regulation of eclosion,biological_process
75555,GO:0045806,"Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.",negative regulation of endocytosis,biological_process
75556,GO:0045807,"Any process that activates or increases the frequency, rate or extent of endocytosis.",positive regulation of endocytosis,biological_process
75557,GO:0045808,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.",negative regulation of establishment of competence for transformation,biological_process
75558,GO:0045809,"Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation.",positive regulation of establishment of competence for transformation,biological_process
75559,GO:0045812,"Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).","negative regulation of Wnt signaling pathway, calcium modulating pathway",biological_process
75560,GO:0045813,"Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).","positive regulation of Wnt signaling pathway, calcium modulating pathway",biological_process
75561,GO:0045814,"An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation.","negative regulation of gene expression, epigenetic",biological_process
75562,GO:0045815,"An epigenetic mechanism of regulation of gene expression that involves chromatin remodeling to capacitate gene expression by either modifying the chromatin fiber, the nucleosomal histones, or the DNA.",transcription initiation-coupled chromatin remodeling,biological_process
75563,GO:0045818,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.",negative regulation of glycogen catabolic process,biological_process
75564,GO:0045819,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.",positive regulation of glycogen catabolic process,biological_process
75565,GO:0045820,"Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.",negative regulation of glycolytic process,biological_process
75566,GO:0045821,"Any process that activates or increases the frequency, rate or extent of glycolysis.",positive regulation of glycolytic process,biological_process
75567,GO:0045822,"Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.",negative regulation of heart contraction,biological_process
75568,GO:0045823,"Any process that activates or increases the frequency, rate or extent of heart contraction.",positive regulation of heart contraction,biological_process
75569,GO:0045824,"Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.",negative regulation of innate immune response,biological_process
75570,GO:0045827,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.",negative regulation of isoprenoid metabolic process,biological_process
75571,GO:0045829,"Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.",negative regulation of isotype switching,biological_process
75572,GO:0045830,"Any process that activates or increases the frequency, rate or extent of isotype switching.",positive regulation of isotype switching,biological_process
75573,GO:0045833,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.",negative regulation of lipid metabolic process,biological_process
75574,GO:0045834,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.",positive regulation of lipid metabolic process,biological_process
75575,GO:0045835,"Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.",negative regulation of meiotic nuclear division,biological_process
75576,GO:0045836,"Any process that activates or increases the frequency, rate or extent of meiosis.",positive regulation of meiotic nuclear division,biological_process
75577,GO:0045837,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",negative regulation of membrane potential,biological_process
75578,GO:0045838,"Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",positive regulation of membrane potential,biological_process
75579,GO:0045839,"Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.",negative regulation of mitotic nuclear division,biological_process
75580,GO:0045840,"Any process that activates or increases the frequency, rate or extent of mitosis.",positive regulation of mitotic nuclear division,biological_process
75581,GO:0045841,"Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.",negative regulation of mitotic metaphase/anaphase transition,biological_process
75582,GO:0045842,"Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.",positive regulation of mitotic metaphase/anaphase transition,biological_process
75583,GO:0045843,"Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.",negative regulation of striated muscle tissue development,biological_process
75584,GO:0045844,"Any process that activates or increases the frequency, rate or extent of striated muscle development.",positive regulation of striated muscle tissue development,biological_process
75585,GO:0045847,"Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization.",negative regulation of nitrogen utilization,biological_process
75586,GO:0045848,"Any process that activates or increases the frequency, rate or extent of nitrogen utilization.",positive regulation of nitrogen utilization,biological_process
75587,GO:0045849,"Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process.",negative regulation of nurse cell apoptotic process,biological_process
75588,GO:0045850,"Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.",positive regulation of nurse cell apoptotic process,biological_process
75589,GO:0045851,"Any process that reduces the internal pH of an organism, part of an organism or a cell, corresponding to an increase in hydrogen ion concentration.",pH reduction,biological_process
75590,GO:0045852,"Any process that increases the internal pH of an organism, part of an organism or a cell, corresponding to a decrease in hydrogen ion concentration.",pH elevation,biological_process
75591,GO:0045853,"Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.",negative regulation of bicoid mRNA localization,biological_process
75592,GO:0045854,"Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.",positive regulation of bicoid mRNA localization,biological_process
75593,GO:0045855,"Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the germ plasm.",negative regulation of germ plasm oskar mRNA localization,biological_process
75594,GO:0045856,"Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the germ plasm.",positive regulation of germ plasm oskar mRNA localization,biological_process
75595,GO:0045859,"Any process that modulates the frequency, rate or extent of protein kinase activity.",regulation of protein kinase activity,biological_process
75596,GO:0045860,"Any process that activates or increases the frequency, rate or extent of protein kinase activity.",positive regulation of protein kinase activity,biological_process
75597,GO:0045861,"Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.",negative regulation of proteolysis,biological_process
75598,GO:0045862,"Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.",positive regulation of proteolysis,biological_process
75599,GO:0045869,"Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.",negative regulation of single stranded viral RNA replication via double stranded DNA intermediate,biological_process
75600,GO:0045870,"Any process that activates or increases the frequency, rate or extent of retroviral genome replication.",positive regulation of single stranded viral RNA replication via double stranded DNA intermediate,biological_process
75601,GO:0045873,"Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.",negative regulation of sevenless signaling pathway,biological_process
75602,GO:0045874,"Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.",positive regulation of sevenless signaling pathway,biological_process
75603,GO:0045875,"Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.",negative regulation of sister chromatid cohesion,biological_process
75604,GO:0045876,"Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.",positive regulation of sister chromatid cohesion,biological_process
75605,GO:0045879,"Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.",negative regulation of smoothened signaling pathway,biological_process
75606,GO:0045880,"Any process that activates or increases the frequency, rate or extent of smoothened signaling.",positive regulation of smoothened signaling pathway,biological_process
75607,GO:0045881,"Any process that activates or increases the frequency, rate or extent of sporulation.",positive regulation of sporulation resulting in formation of a cellular spore,biological_process
75608,GO:0045882,"Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.",negative regulation of sulfur utilization,biological_process
75609,GO:0045883,"Any process that activates or increases the frequency, rate or extent of sulfur utilization.",positive regulation of sulfur utilization,biological_process
75610,GO:0045886,"Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction.",negative regulation of synaptic assembly at neuromuscular junction,biological_process
75611,GO:0045887,"Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction.",positive regulation of synaptic assembly at neuromuscular junction,biological_process
75612,GO:0045892,"Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.",negative regulation of DNA-templated transcription,biological_process
75613,GO:0045893,"Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.",positive regulation of DNA-templated transcription,biological_process
75614,GO:0045894,"Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.","negative regulation of mating-type specific transcription, DNA-templated",biological_process
75615,GO:0045895,Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.,"positive regulation of mating-type specific transcription, DNA-templated",biological_process
75616,GO:0045898,"Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.",regulation of RNA polymerase II transcription preinitiation complex assembly,biological_process
75617,GO:0045899,"Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.",positive regulation of RNA polymerase II transcription preinitiation complex assembly,biological_process
75618,GO:0045900,"Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.",negative regulation of translational elongation,biological_process
75619,GO:0045901,"Any process that activates or increases the frequency, rate or extent of translational elongation.",positive regulation of translational elongation,biological_process
75620,GO:0045902,Any process that decreases the ability of the translational apparatus to interpret the genetic code.,negative regulation of translational fidelity,biological_process
75621,GO:0045903,Any process that increases the ability of the translational apparatus to interpret the genetic code.,positive regulation of translational fidelity,biological_process
75622,GO:0045904,"Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.",negative regulation of translational termination,biological_process
75623,GO:0045905,"Any process that activates or increases the frequency, rate or extent of translational termination.",positive regulation of translational termination,biological_process
75624,GO:0045906,"Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.",negative regulation of vasoconstriction,biological_process
75625,GO:0045907,"Any process that activates or increases the frequency, rate or extent of vasoconstriction.",positive regulation of vasoconstriction,biological_process
75626,GO:0045910,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.",negative regulation of DNA recombination,biological_process
75627,GO:0045911,"Any process that activates or increases the frequency, rate or extent of DNA recombination.",positive regulation of DNA recombination,biological_process
75628,GO:0045912,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.",negative regulation of carbohydrate metabolic process,biological_process
75629,GO:0045913,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.",positive regulation of carbohydrate metabolic process,biological_process
75630,GO:0045916,"Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.",negative regulation of complement activation,biological_process
75631,GO:0045917,"Any process that activates or increases the frequency, rate or extent of complement activation.",positive regulation of complement activation,biological_process
75632,GO:0045918,"Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis.",negative regulation of cytolysis,biological_process
75633,GO:0045919,"Any process that activates or increases the frequency, rate or extent of cytolysis.",positive regulation of cytolysis,biological_process
75634,GO:0045920,"Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.",negative regulation of exocytosis,biological_process
75635,GO:0045921,"Any process that activates or increases the frequency, rate or extent of exocytosis.",positive regulation of exocytosis,biological_process
75636,GO:0045922,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.",negative regulation of fatty acid metabolic process,biological_process
75637,GO:0045923,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.",positive regulation of fatty acid metabolic process,biological_process
75638,GO:0045924,"Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.",regulation of female receptivity,biological_process
75639,GO:0045925,Any process that activates or increases the receptiveness of a female to male advances.,positive regulation of female receptivity,biological_process
75640,GO:0045926,"Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.",negative regulation of growth,biological_process
75641,GO:0045927,"Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.",positive regulation of growth,biological_process
75642,GO:0045928,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.",negative regulation of juvenile hormone metabolic process,biological_process
75643,GO:0045930,"Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.",negative regulation of mitotic cell cycle,biological_process
75644,GO:0045931,Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.,positive regulation of mitotic cell cycle,biological_process
75645,GO:0045932,"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.",negative regulation of muscle contraction,biological_process
75646,GO:0045933,"Any process that activates or increases the frequency, rate or extent of muscle contraction.",positive regulation of muscle contraction,biological_process
75647,GO:0045934,"Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.",negative regulation of nucleobase-containing compound metabolic process,biological_process
75648,GO:0045936,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.",negative regulation of phosphate metabolic process,biological_process
75649,GO:0045937,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.",positive regulation of phosphate metabolic process,biological_process
75650,GO:0045938,"Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.","positive regulation of circadian sleep/wake cycle, sleep",biological_process
75651,GO:0045939,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.",negative regulation of steroid metabolic process,biological_process
75652,GO:0045940,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.",positive regulation of steroid metabolic process,biological_process
75653,GO:0045942,"Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.",negative regulation of phosphorus utilization,biological_process
75654,GO:0045943,"Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.",positive regulation of transcription by RNA polymerase I,biological_process
75655,GO:0045944,"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.",positive regulation of transcription by RNA polymerase II,biological_process
75656,GO:0045945,"Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.",positive regulation of transcription by RNA polymerase III,biological_process
75657,GO:0045947,"Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.",negative regulation of translational initiation,biological_process
75658,GO:0045948,"Any process that activates or increases the frequency, rate or extent of translational initiation.",positive regulation of translational initiation,biological_process
75659,GO:0045949,"Any process that activates or increases the frequency, rate or extent of phosphorus utilization.",positive regulation of phosphorus utilization,biological_process
75660,GO:0045950,Any process that inhibits or decreases the rate of DNA recombination during mitosis.,negative regulation of mitotic recombination,biological_process
75661,GO:0045951,"Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.",positive regulation of mitotic recombination,biological_process
75662,GO:0045952,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.",regulation of juvenile hormone catabolic process,biological_process
75663,GO:0045953,"Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.",negative regulation of natural killer cell mediated cytotoxicity,biological_process
75664,GO:0045954,"Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.",positive regulation of natural killer cell mediated cytotoxicity,biological_process
75665,GO:0045955,"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.",negative regulation of calcium ion-dependent exocytosis,biological_process
75666,GO:0045956,"Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.",positive regulation of calcium ion-dependent exocytosis,biological_process
75667,GO:0045957,"Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.","negative regulation of complement activation, alternative pathway",biological_process
75668,GO:0045958,"Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.","positive regulation of complement activation, alternative pathway",biological_process
75669,GO:0045959,"Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.","negative regulation of complement activation, classical pathway",biological_process
75670,GO:0045960,"Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.","positive regulation of complement activation, classical pathway",biological_process
75671,GO:0045961,Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.,"negative regulation of development, heterochronic",biological_process
75672,GO:0045962,Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.,"positive regulation of development, heterochronic",biological_process
75673,GO:0045963,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.",negative regulation of dopamine metabolic process,biological_process
75674,GO:0045964,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.",positive regulation of dopamine metabolic process,biological_process
75675,GO:0045967,Any process that reduces the rate of growth of all or part of an organism.,negative regulation of growth rate,biological_process
75676,GO:0045968,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.",negative regulation of juvenile hormone biosynthetic process,biological_process
75677,GO:0045969,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.",positive regulation of juvenile hormone biosynthetic process,biological_process
75678,GO:0045970,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.",negative regulation of juvenile hormone catabolic process,biological_process
75679,GO:0045971,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.",positive regulation of juvenile hormone catabolic process,biological_process
75680,GO:0045972,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.",negative regulation of juvenile hormone secretion,biological_process
75681,GO:0045973,"Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.",positive regulation of juvenile hormone secretion,biological_process
75682,GO:0045974,"Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.","regulation of translation, ncRNA-mediated",biological_process
75683,GO:0045975,"Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein.","positive regulation of translation, ncRNA-mediated",biological_process
75684,GO:0045976,"Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle.","negative regulation of mitotic cell cycle, embryonic",biological_process
75685,GO:0045977,"Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.","positive regulation of mitotic cell cycle, embryonic",biological_process
75686,GO:0045978,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.",negative regulation of nucleoside metabolic process,biological_process
75687,GO:0045979,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.",positive regulation of nucleoside metabolic process,biological_process
75688,GO:0045980,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.",negative regulation of nucleotide metabolic process,biological_process
75689,GO:0045981,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.",positive regulation of nucleotide metabolic process,biological_process
75690,GO:0045982,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.",negative regulation of purine nucleobase metabolic process,biological_process
75691,GO:0045983,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.",positive regulation of purine nucleobase metabolic process,biological_process
75692,GO:0045984,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.",negative regulation of pyrimidine nucleobase metabolic process,biological_process
75693,GO:0045985,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.",positive regulation of pyrimidine nucleobase metabolic process,biological_process
75694,GO:0045986,"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.",negative regulation of smooth muscle contraction,biological_process
75695,GO:0045987,"Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.",positive regulation of smooth muscle contraction,biological_process
75696,GO:0045988,"Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.",negative regulation of striated muscle contraction,biological_process
75697,GO:0045989,"Any process that activates or increases the frequency, rate or extent of striated muscle contraction.",positive regulation of striated muscle contraction,biological_process
75698,GO:0045990,"A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.",carbon catabolite regulation of transcription,biological_process
75699,GO:0045991,"A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.",carbon catabolite activation of transcription,biological_process
75700,GO:0045992,"Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.",negative regulation of embryonic development,biological_process
75701,GO:0045993,"Any process involving iron that stops, prevents or reduces the rate of translational initiation.",negative regulation of translational initiation by iron,biological_process
75702,GO:0045994,Any process involving iron that activates or increases the rate of translational initiation.,positive regulation of translational initiation by iron,biological_process
75703,GO:0045995,"Any process that modulates the frequency, rate or extent of embryonic development.",regulation of embryonic development,biological_process
75704,GO:0045997,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.",negative regulation of ecdysteroid biosynthetic process,biological_process
75705,GO:0045998,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.",positive regulation of ecdysteroid biosynthetic process,biological_process
75706,GO:0045999,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.",negative regulation of ecdysteroid secretion,biological_process
75707,GO:0046000,"Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.",positive regulation of ecdysteroid secretion,biological_process
75708,GO:0046001,"Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle.",negative regulation of preblastoderm mitotic cell cycle,biological_process
75709,GO:0046002,Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.,positive regulation of preblastoderm mitotic cell cycle,biological_process
75710,GO:0046003,"Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.",negative regulation of syncytial blastoderm mitotic cell cycle,biological_process
75711,GO:0046004,Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.,positive regulation of syncytial blastoderm mitotic cell cycle,biological_process
75712,GO:0046005,Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.,"positive regulation of circadian sleep/wake cycle, REM sleep",biological_process
75713,GO:0046006,"Any process that modulates the frequency, rate or extent of activated T cell proliferation.",regulation of activated T cell proliferation,biological_process
75714,GO:0046007,"Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.",negative regulation of activated T cell proliferation,biological_process
75715,GO:0046008,Any process that modulates the receptiveness of a female to male advances subsequent to mating.,"regulation of female receptivity, post-mating",biological_process
75716,GO:0046009,Any process that increases the receptiveness of a female to male advances subsequent to mating.,"positive regulation of female receptivity, post-mating",biological_process
75717,GO:0046010,Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.,"positive regulation of circadian sleep/wake cycle, non-REM sleep",biological_process
75718,GO:0046011,"Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.",regulation of oskar mRNA translation,biological_process
75719,GO:0046012,"Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.",positive regulation of oskar mRNA translation,biological_process
75720,GO:0046013,"Any process that modulates the frequency, rate or extent of resting T cell proliferation.",regulation of T cell homeostatic proliferation,biological_process
75721,GO:0046014,"Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.",negative regulation of T cell homeostatic proliferation,biological_process
75722,GO:0046015,"Any process involving glucose that modulates the frequency, rate or extent or transcription.",regulation of transcription by glucose,biological_process
75723,GO:0046016,Any process involving glucose that activates or increases the rate of transcription.,positive regulation of transcription by glucose,biological_process
75724,GO:0046025,Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.,"precorrin-6Y C5,15-methyltransferase (decarboxylating) activity",molecular_function
75725,GO:0046026,Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.,precorrin-4 C11-methyltransferase activity,molecular_function
75726,GO:0046027,"Catalysis of the reaction: a glycerophospholipid + a 1,2-diacyl-sn-glycerol = a monoacylglycerophospholipid + a triacyl-sn-glycerol.",phospholipid:diacylglycerol acyltransferase activity,molecular_function
75727,GO:0046029,Catalysis of the reaction: D-mannitol + NAD+ = D-mannose + H+ + NADH.,mannitol dehydrogenase activity,molecular_function
75728,GO:0046030,Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.,inositol trisphosphate phosphatase activity,molecular_function
75729,GO:0046031,"The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.",ADP metabolic process,biological_process
75730,GO:0046032,"The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.",ADP catabolic process,biological_process
75731,GO:0046033,"The chemical reactions and pathways involving AMP, adenosine monophosphate.",AMP metabolic process,biological_process
75732,GO:0046034,"The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.",ATP metabolic process,biological_process
75733,GO:0046035,"The chemical reactions and pathways involving CMP, cytidine monophosphate.",CMP metabolic process,biological_process
75734,GO:0046036,"The chemical reactions and pathways involving CTP, cytidine triphosphate.",CTP metabolic process,biological_process
75735,GO:0046037,"The chemical reactions and pathways involving GMP, guanosine monophosphate.",GMP metabolic process,biological_process
75736,GO:0046038,"The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.",GMP catabolic process,biological_process
75737,GO:0046039,"The chemical reactions and pathways involving GTP, guanosine triphosphate.",GTP metabolic process,biological_process
75738,GO:0046040,"The chemical reactions and pathways involving IMP, inosine monophosphate.",IMP metabolic process,biological_process
75739,GO:0046041,"The chemical reactions and pathways involving ITP, inosine triphosphate.",ITP metabolic process,biological_process
75740,GO:0046042,"The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate.",ITP biosynthetic process,biological_process
75741,GO:0046043,"The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.",TDP metabolic process,biological_process
75742,GO:0046044,"The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.",TMP metabolic process,biological_process
75743,GO:0046045,"The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.",TMP catabolic process,biological_process
75744,GO:0046046,"The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.",TTP metabolic process,biological_process
75745,GO:0046047,"The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.",TTP catabolic process,biological_process
75746,GO:0046048,"The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.",UDP metabolic process,biological_process
75747,GO:0046049,"The chemical reactions and pathways involving UMP, uridine monophosphate.",UMP metabolic process,biological_process
75748,GO:0046050,"The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.",UMP catabolic process,biological_process
75749,GO:0046051,"The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.",UTP metabolic process,biological_process
75750,GO:0046052,"The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.",UTP catabolic process,biological_process
75751,GO:0046053,"The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).",dAMP metabolic process,biological_process
75752,GO:0046054,"The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).",dGMP metabolic process,biological_process
75753,GO:0046055,"The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).",dGMP catabolic process,biological_process
75754,GO:0046056,"The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).",dADP metabolic process,biological_process
75755,GO:0046057,"The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).",dADP catabolic process,biological_process
75756,GO:0046058,"The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).",cAMP metabolic process,biological_process
75757,GO:0046059,"The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).",dAMP catabolic process,biological_process
75758,GO:0046060,"The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).",dATP metabolic process,biological_process
75759,GO:0046061,"The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).",dATP catabolic process,biological_process
75760,GO:0046062,"The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.",dCDP metabolic process,biological_process
75761,GO:0046063,"The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.",dCMP metabolic process,biological_process
75762,GO:0046064,"The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.",dCMP biosynthetic process,biological_process
75763,GO:0046065,"The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.",dCTP metabolic process,biological_process
75764,GO:0046066,"The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).",dGDP metabolic process,biological_process
75765,GO:0046067,"The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).",dGDP catabolic process,biological_process
75766,GO:0046068,"The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.",cGMP metabolic process,biological_process
75767,GO:0046069,"The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.",cGMP catabolic process,biological_process
75768,GO:0046070,"The chemical reactions and pathways involving dGTP, guanosine triphosphate.",dGTP metabolic process,biological_process
75769,GO:0046071,"The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate.",dGTP biosynthetic process,biological_process
75770,GO:0046072,"The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate.",dTDP metabolic process,biological_process
75771,GO:0046073,"The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).",dTMP metabolic process,biological_process
75772,GO:0046074,"The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.",dTMP catabolic process,biological_process
75773,GO:0046075,"The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.",dTTP metabolic process,biological_process
75774,GO:0046076,"The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.",dTTP catabolic process,biological_process
75775,GO:0046077,"The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.",dUDP metabolic process,biological_process
75776,GO:0046078,"The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate).",dUMP metabolic process,biological_process
75777,GO:0046079,"The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate.",dUMP catabolic process,biological_process
75778,GO:0046080,"The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.",dUTP metabolic process,biological_process
75779,GO:0046081,"The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.",dUTP catabolic process,biological_process
75780,GO:0046083,"The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.",adenine metabolic process,biological_process
75781,GO:0046084,"The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.",adenine biosynthetic process,biological_process
75782,GO:0046085,"The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.",adenosine metabolic process,biological_process
75783,GO:0046086,"The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.",adenosine biosynthetic process,biological_process
75784,GO:0046087,"The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside.",cytidine metabolic process,biological_process
75785,GO:0046090,"The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.",deoxyadenosine metabolic process,biological_process
75786,GO:0046091,"The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.",deoxyadenosine biosynthetic process,biological_process
75787,GO:0046092,"The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.",deoxycytidine metabolic process,biological_process
75788,GO:0046093,"The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.",deoxycytidine biosynthetic process,biological_process
75789,GO:0046094,"The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.",deoxyinosine metabolic process,biological_process
75790,GO:0046095,"The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside.",deoxyinosine biosynthetic process,biological_process
75791,GO:0046096,"The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.",deoxyuridine metabolic process,biological_process
75792,GO:0046097,"The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.",deoxyuridine biosynthetic process,biological_process
75793,GO:0046098,"The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.",guanine metabolic process,biological_process
75794,GO:0046099,"The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.",guanine biosynthetic process,biological_process
75795,GO:0046100,"The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.",hypoxanthine metabolic process,biological_process
75796,GO:0046101,"The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.",hypoxanthine biosynthetic process,biological_process
75797,GO:0046102,"The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.",inosine metabolic process,biological_process
75798,GO:0046103,"The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.",inosine biosynthetic process,biological_process
75799,GO:0046104,"The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.",thymidine metabolic process,biological_process
75800,GO:0046105,"The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.",thymidine biosynthetic process,biological_process
75801,GO:0046106,"The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.",thymine biosynthetic process,biological_process
75802,GO:0046107,"The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.",uracil biosynthetic process,biological_process
75803,GO:0046108,"The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.",uridine metabolic process,biological_process
75804,GO:0046109,"The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.",uridine biosynthetic process,biological_process
75805,GO:0046110,"The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.",xanthine metabolic process,biological_process
75806,GO:0046111,"The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.",xanthine biosynthetic process,biological_process
75807,GO:0046112,"The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.",nucleobase biosynthetic process,biological_process
75808,GO:0046113,"The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.",nucleobase catabolic process,biological_process
75809,GO:0046114,"The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.",guanosine biosynthetic process,biological_process
75810,GO:0046115,"The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution.",guanosine catabolic process,biological_process
75811,GO:0046118,"The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.",7-methylguanosine biosynthetic process,biological_process
75812,GO:0046119,"The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.",7-methylguanosine catabolic process,biological_process
75813,GO:0046120,The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,2'-deoxyribonucleoside biosynthetic process,biological_process
75814,GO:0046121,The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,2'-deoxyribonucleoside catabolic process,biological_process
75815,GO:0046122,The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,purine deoxyribonucleoside metabolic process,biological_process
75816,GO:0046123,"The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).",purine deoxyribonucleoside biosynthetic process,biological_process
75817,GO:0046124,The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,purine deoxyribonucleoside catabolic process,biological_process
75818,GO:0046125,The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,pyrimidine deoxyribonucleoside metabolic process,biological_process
75819,GO:0046126,The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,pyrimidine deoxyribonucleoside biosynthetic process,biological_process
75820,GO:0046127,The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).,pyrimidine deoxyribonucleoside catabolic process,biological_process
75821,GO:0046128,"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.",purine ribonucleoside metabolic process,biological_process
75822,GO:0046129,"The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.",purine ribonucleoside biosynthetic process,biological_process
75823,GO:0046130,"The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.",purine ribonucleoside catabolic process,biological_process
75824,GO:0046131,"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",pyrimidine ribonucleoside metabolic process,biological_process
75825,GO:0046132,"The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",pyrimidine ribonucleoside biosynthetic process,biological_process
75826,GO:0046133,"The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.",pyrimidine ribonucleoside catabolic process,biological_process
75827,GO:0046134,The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).,pyrimidine nucleoside biosynthetic process,biological_process
75828,GO:0046135,The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).,pyrimidine nucleoside catabolic process,biological_process
75829,GO:0046136,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",positive regulation of vitamin metabolic process,biological_process
75830,GO:0046137,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",negative regulation of vitamin metabolic process,biological_process
75831,GO:0046140,"The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.",corrin biosynthetic process,biological_process
75832,GO:0046141,"The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.",corrin catabolic process,biological_process
75833,GO:0046146,"The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.",tetrahydrobiopterin metabolic process,biological_process
75834,GO:0046147,"The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.",tetrahydrobiopterin catabolic process,biological_process
75835,GO:0046148,"The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.",pigment biosynthetic process,biological_process
75836,GO:0046149,"The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.",pigment catabolic process,biological_process
75837,GO:0046150,"The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.",melanin catabolic process,biological_process
75838,GO:0046151,"The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.",eye pigment catabolic process,biological_process
75839,GO:0046152,"The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.",ommochrome metabolic process,biological_process
75840,GO:0046153,"The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.",ommochrome catabolic process,biological_process
75841,GO:0046154,"The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.",rhodopsin metabolic process,biological_process
75842,GO:0046155,"The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.",rhodopsin catabolic process,biological_process
75843,GO:0046157,"The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.",siroheme catabolic process,biological_process
75844,GO:0046158,"The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.",ocellus pigment metabolic process,biological_process
75845,GO:0046159,"The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.",ocellus pigment catabolic process,biological_process
75846,GO:0046161,"The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.",heme a catabolic process,biological_process
75847,GO:0046163,"The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f.",heme C catabolic process,biological_process
75848,GO:0046164,"The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.",alcohol catabolic process,biological_process
75849,GO:0046165,"The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.",alcohol biosynthetic process,biological_process
75850,GO:0046166,"The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.",glyceraldehyde-3-phosphate biosynthetic process,biological_process
75851,GO:0046167,"The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.",glycerol-3-phosphate biosynthetic process,biological_process
75852,GO:0046168,"The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.",glycerol-3-phosphate catabolic process,biological_process
75853,GO:0046169,"The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.",methanol biosynthetic process,biological_process
75854,GO:0046170,"The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.",methanol catabolic process,biological_process
75855,GO:0046171,"The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.",octanol biosynthetic process,biological_process
75856,GO:0046172,"The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.",octanol catabolic process,biological_process
75857,GO:0046173,"The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.",polyol biosynthetic process,biological_process
75858,GO:0046174,"The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.",polyol catabolic process,biological_process
75859,GO:0046175,"The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.",aldonic acid biosynthetic process,biological_process
75860,GO:0046176,"The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.",aldonic acid catabolic process,biological_process
75861,GO:0046178,"The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.",D-gluconate biosynthetic process,biological_process
75862,GO:0046179,"The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.",keto-D-gluconate biosynthetic process,biological_process
75863,GO:0046182,"The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.",L-idonate biosynthetic process,biological_process
75864,GO:0046183,"The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.",L-idonate catabolic process,biological_process
75865,GO:0046184,"The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.",aldehyde biosynthetic process,biological_process
75866,GO:0046185,"The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.",aldehyde catabolic process,biological_process
75867,GO:0046186,"The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.",acetaldehyde biosynthetic process,biological_process
75868,GO:0046187,"The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.",acetaldehyde catabolic process,biological_process
75869,GO:0046188,"The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.",methane catabolic process,biological_process
75870,GO:0046189,"The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.",phenol-containing compound biosynthetic process,biological_process
75871,GO:0046190,"The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.",aerobic phenol-containing compound biosynthetic process,biological_process
75872,GO:0046191,"The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.",aerobic phenol-containing compound catabolic process,biological_process
75873,GO:0046192,"The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.",anaerobic phenol-containing compound biosynthetic process,biological_process
75874,GO:0046193,"The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.",anaerobic phenol-containing compound catabolic process,biological_process
75875,GO:0046196,"The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.",4-nitrophenol catabolic process,biological_process
75876,GO:0046197,"The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.",orcinol biosynthetic process,biological_process
75877,GO:0046199,"The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.",cresol catabolic process,biological_process
75878,GO:0046201,"The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid.",cyanate biosynthetic process,biological_process
75879,GO:0046202,"The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.",cyanide biosynthetic process,biological_process
75880,GO:0046203,"The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",spermidine catabolic process,biological_process
75881,GO:0046204,"The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",nor-spermidine metabolic process,biological_process
75882,GO:0046205,"The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.",nor-spermidine catabolic process,biological_process
75883,GO:0046206,"The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.",trypanothione metabolic process,biological_process
75884,GO:0046207,"The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.",trypanothione catabolic process,biological_process
75885,GO:0046208,"The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.",spermine catabolic process,biological_process
75886,GO:0046209,"The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.",nitric oxide metabolic process,biological_process
75887,GO:0046210,"The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.",nitric oxide catabolic process,biological_process
75888,GO:0046211,"The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone. Consists of the three reactions: (2E)-geranyl diphosphate = (2S,4R)-bornyl diphosphate, which is converted to (1R,2S,4R)-borneol + diphosphate, and then to (1R,4R)-camphor.",(+)-camphor biosynthetic process,biological_process
75889,GO:0046213,"The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor.",methyl ethyl ketone catabolic process,biological_process
75890,GO:0046214,"The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.",enterobactin catabolic process,biological_process
75891,GO:0046215,"The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.",siderophore catabolic process,biological_process
75892,GO:0046216,"The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.",indole phytoalexin catabolic process,biological_process
75893,GO:0046219,"The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.",indolalkylamine biosynthetic process,biological_process
75894,GO:0046220,"The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.",pyridine biosynthetic process,biological_process
75895,GO:0046221,"The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.",pyridine catabolic process,biological_process
75896,GO:0046222,"The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.",aflatoxin metabolic process,biological_process
75897,GO:0046223,"The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.",aflatoxin catabolic process,biological_process
75898,GO:0046224,"The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.",bacteriocin metabolic process,biological_process
75899,GO:0046225,"The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.",bacteriocin catabolic process,biological_process
75900,GO:0046226,"The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.",coumarin catabolic process,biological_process
75901,GO:0046228,"The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.","2,4,5-trichlorophenoxyacetic acid catabolic process",biological_process
75902,GO:0046230,"The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.",2-aminobenzenesulfonate catabolic process,biological_process
75903,GO:0046232,"The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.",carbazole catabolic process,biological_process
75904,GO:0046236,"The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.",mandelate biosynthetic process,biological_process
75905,GO:0046239,"The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid.",phthalate catabolic process,biological_process
75906,GO:0046244,"The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.",salicylic acid catabolic process,biological_process
75907,GO:0046246,"The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.",terpene biosynthetic process,biological_process
75908,GO:0046247,"The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.",terpene catabolic process,biological_process
75909,GO:0046248,"The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.",alpha-pinene biosynthetic process,biological_process
75910,GO:0046249,"The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.",alpha-pinene catabolic process,biological_process
75911,GO:0046250,"The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.",limonene biosynthetic process,biological_process
75912,GO:0046251,"The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.",limonene catabolic process,biological_process
75913,GO:0046252,"The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.",toluene biosynthetic process,biological_process
75914,GO:0046253,"The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.",anaerobic toluene biosynthetic process,biological_process
75915,GO:0046254,"The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.",anaerobic toluene catabolic process,biological_process
75916,GO:0046256,"The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.","2,4,6-trinitrotoluene catabolic process",biological_process
75917,GO:0046258,"The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.","anaerobic 2,4,6-trinitrotoluene catabolic process",biological_process
75918,GO:0046260,"The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.",trinitrotoluene catabolic process,biological_process
75919,GO:0046263,"The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.",nitrotoluene catabolic process,biological_process
75920,GO:0046265,"The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.",thiocyanate catabolic process,biological_process
75921,GO:0046269,"The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.",toluene-4-sulfonate catabolic process,biological_process
75922,GO:0046271,The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid.,phenylpropanoid catabolic process,biological_process
75923,GO:0046272,"The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.",stilbene catabolic process,biological_process
75924,GO:0046273,"The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.",lignan catabolic process,biological_process
75925,GO:0046274,"The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.",lignin catabolic process,biological_process
75926,GO:0046275,"The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.",flavonoid catabolic process,biological_process
75927,GO:0046276,"The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.",methylgallate catabolic process,biological_process
75928,GO:0046277,"The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.",methylgallate biosynthetic process,biological_process
75929,GO:0046278,"The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).","3,4-dihydroxybenzoate metabolic process",biological_process
75930,GO:0046279,"The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.","3,4-dihydroxybenzoate biosynthetic process",biological_process
75931,GO:0046280,"The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.",chalcone catabolic process,biological_process
75932,GO:0046281,"The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.",cinnamic acid catabolic process,biological_process
75933,GO:0046282,"The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.",cinnamic acid ester catabolic process,biological_process
75934,GO:0046283,"The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.",anthocyanin-containing compound metabolic process,biological_process
75935,GO:0046284,"The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.",anthocyanin-containing compound catabolic process,biological_process
75936,GO:0046286,"The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.",flavonoid phytoalexin catabolic process,biological_process
75937,GO:0046287,"The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.",isoflavonoid metabolic process,biological_process
75938,GO:0046288,"The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.",isoflavonoid catabolic process,biological_process
75939,GO:0046290,"The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.",isoflavonoid phytoalexin catabolic process,biological_process
75940,GO:0046292,"The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.",formaldehyde metabolic process,biological_process
75941,GO:0046293,"The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.",formaldehyde biosynthetic process,biological_process
75942,GO:0046294,"The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.",formaldehyde catabolic process,biological_process
75943,GO:0046295,"The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).",glycolate biosynthetic process,biological_process
75944,GO:0046296,"The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).",glycolate catabolic process,biological_process
75945,GO:0046298,"The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).","2,4-dichlorobenzoate catabolic process",biological_process
75946,GO:0046300,"The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.","2,4-dichlorophenoxyacetic acid catabolic process",biological_process
75947,GO:0046302,"The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.",2-chloro-N-isopropylacetanilide catabolic process,biological_process
75948,GO:0046304,"The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.",2-nitropropane catabolic process,biological_process
75949,GO:0046305,"The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.",alkanesulfonate biosynthetic process,biological_process
75950,GO:0046306,"The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.",alkanesulfonate catabolic process,biological_process
75951,GO:0046307,"The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.",Z-phenylacetaldoxime biosynthetic process,biological_process
75952,GO:0046308,"The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.",Z-phenylacetaldoxime catabolic process,biological_process
75953,GO:0046311,"The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.",prenylcysteine biosynthetic process,biological_process
75954,GO:0046314,"The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.",phosphocreatine biosynthetic process,biological_process
75955,GO:0046315,"The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.",phosphocreatine catabolic process,biological_process
75956,GO:0046316,Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H+.,gluconokinase activity,molecular_function
75957,GO:0046317,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.",regulation of glucosylceramide biosynthetic process,biological_process
75958,GO:0046318,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.",negative regulation of glucosylceramide biosynthetic process,biological_process
75959,GO:0046319,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.",positive regulation of glucosylceramide biosynthetic process,biological_process
75960,GO:0046320,"Any process that modulates the frequency, rate or extent of fatty acid oxidation.",regulation of fatty acid oxidation,biological_process
75961,GO:0046321,"Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.",positive regulation of fatty acid oxidation,biological_process
75962,GO:0046322,"Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.",negative regulation of fatty acid oxidation,biological_process
75963,GO:0046324,"Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell.",regulation of D-glucose import across plasma membrane,biological_process
75964,GO:0046325,"Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell.",negative regulation of D-glucose import across plasma membrane,biological_process
75965,GO:0046326,"Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell.",positive regulation of D-glucose import across plasma membrane,biological_process
75966,GO:0046328,"Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.",regulation of JNK cascade,biological_process
75967,GO:0046329,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.",negative regulation of JNK cascade,biological_process
75968,GO:0046330,"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.",positive regulation of JNK cascade,biological_process
75969,GO:0046331,Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.,lateral inhibition,biological_process
75970,GO:0046332,Binding to a SMAD signaling protein.,SMAD binding,molecular_function
75971,GO:0046333,"The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.",octopamine metabolic process,biological_process
75972,GO:0046334,"The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.",octopamine catabolic process,biological_process
75973,GO:0046335,"The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).",ethanolamine biosynthetic process,biological_process
75974,GO:0046336,"The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).",ethanolamine catabolic process,biological_process
75975,GO:0046337,"The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.",phosphatidylethanolamine metabolic process,biological_process
75976,GO:0046338,"The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.",phosphatidylethanolamine catabolic process,biological_process
75977,GO:0046339,"The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.",diacylglycerol metabolic process,biological_process
75978,GO:0046340,"The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.",diacylglycerol catabolic process,biological_process
75979,GO:0046341,"The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.",CDP-diacylglycerol metabolic process,biological_process
75980,GO:0046342,"The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.",CDP-diacylglycerol catabolic process,biological_process
75981,GO:0046344,"The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.",ecdysteroid catabolic process,biological_process
75982,GO:0046345,"The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.",abscisic acid catabolic process,biological_process
75983,GO:0046346,"The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.",mannosamine catabolic process,biological_process
75984,GO:0046347,"The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.",mannosamine biosynthetic process,biological_process
75985,GO:0046348,"The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.",amino sugar catabolic process,biological_process
75986,GO:0046349,"The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.",amino sugar biosynthetic process,biological_process
75987,GO:0046351,"The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.",disaccharide biosynthetic process,biological_process
75988,GO:0046352,"The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.",disaccharide catabolic process,biological_process
75989,GO:0046353,Catalysis of the reaction: a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3)-acetyl-2-deoxystreptamine antibiotic + CoA + H+.,aminoglycoside 3-N-acetyltransferase activity,molecular_function
75990,GO:0046354,"The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.",mannan biosynthetic process,biological_process
75991,GO:0046355,"The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.",mannan catabolic process,biological_process
75992,GO:0046356,"The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.",acetyl-CoA catabolic process,biological_process
75993,GO:0046357,"The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.",D-galactarate biosynthetic process,biological_process
75994,GO:0046358,"The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.",butyrate biosynthetic process,biological_process
75995,GO:0046359,"The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.",butyrate catabolic process,biological_process
75996,GO:0046360,"The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.",2-oxobutyrate biosynthetic process,biological_process
75997,GO:0046362,"The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.",ribitol biosynthetic process,biological_process
75998,GO:0046363,"The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.",ribitol catabolic process,biological_process
75999,GO:0046364,"The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.",monosaccharide biosynthetic process,biological_process
76000,GO:0046365,"The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.",monosaccharide catabolic process,biological_process
76001,GO:0046368,"The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.",GDP-L-fucose metabolic process,biological_process
76002,GO:0046369,"The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.",galactose biosynthetic process,biological_process
76003,GO:0046370,"The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.",fructose biosynthetic process,biological_process
76004,GO:0046373,"The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.",L-arabinose metabolic process,biological_process
76005,GO:0046374,"The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.",teichoic acid metabolic process,biological_process
76006,GO:0046377,"The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.",colanic acid metabolic process,biological_process
76007,GO:0046378,"The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.",enterobacterial common antigen metabolic process,biological_process
76008,GO:0046380,"The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.",N-acetylneuraminate biosynthetic process,biological_process
76009,GO:0046381,"The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.",CMP-N-acetylneuraminate metabolic process,biological_process
76010,GO:0046385,"The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.",deoxyribose phosphate biosynthetic process,biological_process
76011,GO:0046386,"The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.",deoxyribose phosphate catabolic process,biological_process
76012,GO:0046390,"The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.",ribose phosphate biosynthetic process,biological_process
76013,GO:0046391,"The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.",5-phosphoribose 1-diphosphate metabolic process,biological_process
76014,GO:0046392,"The chemical reactions and pathways resulting in the breakdown of D-galactarate, the anion of galactaric acid.",D-galactarate catabolic process,biological_process
76015,GO:0046394,"The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.",carboxylic acid biosynthetic process,biological_process
76016,GO:0046395,"The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.",carboxylic acid catabolic process,biological_process
76017,GO:0046396,"The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.",D-galacturonate metabolic process,biological_process
76018,GO:0046397,"The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.",galacturonate catabolic process,biological_process
76019,GO:0046398,"The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.",UDP-glucuronate metabolic process,biological_process
76020,GO:0046399,"The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.",glucuronate biosynthetic process,biological_process
76021,GO:0046403,Catalysis of the reaction: a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O = a 3'-end 2'-deoxyribonucleotide-DNA + phosphate.,polynucleotide 3'-phosphatase activity,molecular_function
76022,GO:0046404,Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.,ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity,molecular_function
76023,GO:0046405,Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O.,glycerol dehydratase activity,molecular_function
76024,GO:0046406,Catalysis of the reaction: Mg-protoporphyrin IX + S-adenosyl-L-methionine = Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine.,magnesium protoporphyrin IX methyltransferase activity,molecular_function
76025,GO:0046408,Catalysis of the reaction: chlorophyllide a + phytyl diphosphate + 2 H+ = chlorophyll a + diphosphate.,chlorophyll synthetase activity,molecular_function
76026,GO:0046409,Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.,p-coumarate 3-hydroxylase activity,molecular_function
76027,GO:0046411,"The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other.",2-keto-3-deoxygluconate transmembrane transport,biological_process
76028,GO:0046415,"The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.",urate metabolic process,biological_process
76029,GO:0046417,"The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.",chorismate metabolic process,biological_process
76030,GO:0046421,"Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.",methylisocitrate lyase activity,molecular_function
76031,GO:0046422,Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.,violaxanthin de-epoxidase activity,molecular_function
76032,GO:0046423,"Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.",allene-oxide cyclase activity,molecular_function
76033,GO:0046424,Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.,ferulate 5-hydroxylase activity,molecular_function
76034,GO:0046425,"Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.",regulation of receptor signaling pathway via JAK-STAT,biological_process
76035,GO:0046426,"Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.",negative regulation of receptor signaling pathway via JAK-STAT,biological_process
76036,GO:0046427,"Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.",positive regulation of receptor signaling pathway via JAK-STAT,biological_process
76037,GO:0046428,"Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H+ = a 2-demethylmenaquinol + CO2 + diphosphate.","1,4-dihydroxy-2-naphthoate polyprenyltransferase activity",molecular_function
76038,GO:0046429,"Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.",4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin),molecular_function
76039,GO:0046434,"The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.",organophosphate catabolic process,biological_process
76040,GO:0046443,"The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.",FAD metabolic process,biological_process
76041,GO:0046444,"The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.",FMN metabolic process,biological_process
76042,GO:0046446,"The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.",purine alkaloid metabolic process,biological_process
76043,GO:0046447,"The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).",terpenoid indole alkaloid metabolic process,biological_process
76044,GO:0046449,"The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.",creatinine metabolic process,biological_process
76045,GO:0046452,"The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.",dihydrofolate metabolic process,biological_process
76046,GO:0046455,"The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.",organosilicon catabolic process,biological_process
76047,GO:0046456,"The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.",icosanoid biosynthetic process,biological_process
76048,GO:0046457,"The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.",prostanoid biosynthetic process,biological_process
76049,GO:0046458,"The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.",hexadecanal metabolic process,biological_process
76050,GO:0046459,The chemical reactions and pathways involving a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid metabolic process,biological_process
76051,GO:0046460,"The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.",neutral lipid biosynthetic process,biological_process
76052,GO:0046461,"The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.",neutral lipid catabolic process,biological_process
76053,GO:0046462,"The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.",monoacylglycerol metabolic process,biological_process
76054,GO:0046463,"The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.",acylglycerol biosynthetic process,biological_process
76055,GO:0046464,"The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.",acylglycerol catabolic process,biological_process
76056,GO:0046469,"The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.",platelet activating factor metabolic process,biological_process
76057,GO:0046470,"The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.",phosphatidylcholine metabolic process,biological_process
76058,GO:0046471,"The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.",phosphatidylglycerol metabolic process,biological_process
76059,GO:0046473,"The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.",phosphatidic acid metabolic process,biological_process
76060,GO:0046474,"The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.",glycerophospholipid biosynthetic process,biological_process
76061,GO:0046475,"The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.",glycerophospholipid catabolic process,biological_process
76062,GO:0046477,"The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.",glycosylceramide catabolic process,biological_process
76063,GO:0046479,"The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.",glycosphingolipid catabolic process,biological_process
76064,GO:0046480,"Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol.",galactolipid galactosyltransferase activity,molecular_function
76065,GO:0046481,"Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H+ + UDP.",digalactosyldiacylglycerol synthase activity,molecular_function
76066,GO:0046485,"The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.",ether lipid metabolic process,biological_process
76067,GO:0046486,"The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.",glycerolipid metabolic process,biological_process
76068,GO:0046487,"The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.",glyoxylate metabolic process,biological_process
76069,GO:0046488,"The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.",phosphatidylinositol metabolic process,biological_process
76070,GO:0046490,"The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.",isopentenyl diphosphate metabolic process,biological_process
76071,GO:0046491,"The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.",L-methylmalonyl-CoA metabolic process,biological_process
76072,GO:0046493,"The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.",lipid A metabolic process,biological_process
76073,GO:0046495,"The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.",nicotinamide riboside metabolic process,biological_process
76074,GO:0046496,"The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.",nicotinamide nucleotide metabolic process,biological_process
76075,GO:0046499,"The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.",S-adenosylmethioninamine metabolic process,biological_process
76076,GO:0046500,"The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.",S-adenosylmethionine metabolic process,biological_process
76077,GO:0046502,"The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.",uroporphyrinogen III metabolic process,biological_process
76078,GO:0046503,"The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.",glycerolipid catabolic process,biological_process
76079,GO:0046504,"The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.",glycerol ether biosynthetic process,biological_process
76080,GO:0046505,"The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.",sulfolipid metabolic process,biological_process
76081,GO:0046506,"The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.",sulfolipid biosynthetic process,biological_process
76082,GO:0046507,Catalysis of the reaction: sulfite + UDP-D-glucose = H2O + UDP-6-sulfoquinovose.,UDPsulfoquinovose synthase activity,molecular_function
76083,GO:0046508,"Catalysis of the hydrolysis of any carbon-sulfur bond, C-S.","hydrolase activity, acting on carbon-sulfur bonds",molecular_function
76084,GO:0046509,"Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H+ + UDP.","1,2-diacylglycerol 3-beta-galactosyltransferase activity",molecular_function
76085,GO:0046510,"Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.",UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity,molecular_function
76086,GO:0046511,"The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.",sphinganine biosynthetic process,biological_process
76087,GO:0046512,"The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.",sphingosine biosynthetic process,biological_process
76088,GO:0046513,"The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.",ceramide biosynthetic process,biological_process
76089,GO:0046514,"The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.",ceramide catabolic process,biological_process
76090,GO:0046517,"The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.",octamethylcyclotetrasiloxane catabolic process,biological_process
76091,GO:0046519,"The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.",sphingoid metabolic process,biological_process
76092,GO:0046520,"The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.",sphingoid biosynthetic process,biological_process
76093,GO:0046521,"The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.",sphingoid catabolic process,biological_process
76094,GO:0046522,Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H+.,S-methyl-5-thioribose kinase activity,molecular_function
76095,GO:0046523,Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.,S-methyl-5-thioribose-1-phosphate isomerase activity,molecular_function
76096,GO:0046524,Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.,sucrose-phosphate synthase activity,molecular_function
76097,GO:0046525,Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.,xylosylprotein 4-beta-galactosyltransferase activity,molecular_function
76098,GO:0046526,Catalysis of the reaction: NAD+ + xylitol = D-xylulose + H+ + NADH.,D-xylulose reductase activity,molecular_function
76099,GO:0046527,"Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",glucosyltransferase activity,molecular_function
76100,GO:0046528,The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.,imaginal disc fusion,biological_process
76101,GO:0046529,"The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.","imaginal disc fusion, thorax closure",biological_process
76102,GO:0046530,"The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.",photoreceptor cell differentiation,biological_process
76103,GO:0046532,"Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.",regulation of photoreceptor cell differentiation,biological_process
76104,GO:0046533,"Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.",negative regulation of photoreceptor cell differentiation,biological_process
76105,GO:0046534,"Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.",positive regulation of photoreceptor cell differentiation,biological_process
76106,GO:0046536,"A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.",dosage compensation complex,cellular_component
76107,GO:0046539,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H+.,histamine N-methyltransferase activity,molecular_function
76108,GO:0046540,A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs.,U4/U6 x U5 tri-snRNP complex,cellular_component
76109,GO:0046541,"The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.",saliva secretion,biological_process
76110,GO:0046543,"The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female mammals, examples include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.",development of animal secondary female sexual characteristics,biological_process
76111,GO:0046544,"The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male mammals, examples include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.",development of animal secondary male sexual characteristics,biological_process
76112,GO:0046545,"The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.",development of primary female sexual characteristics,biological_process
76113,GO:0046546,"The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.",development of primary male sexual characteristics,biological_process
76114,GO:0046547,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine.,trans-aconitate 3-methyltransferase activity,molecular_function
76115,GO:0046548,"Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.",retinal rod cell development,biological_process
76116,GO:0046549,"Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.",retinal cone cell development,biological_process
76117,GO:0046551,The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.,retinal cone cell fate commitment,biological_process
76118,GO:0046552,The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.,photoreceptor cell fate commitment,biological_process
76119,GO:0046553,Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.,D-malate dehydrogenase (decarboxylating) (NAD+) activity,molecular_function
76120,GO:0046554,Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.,L-malate dehydrogenase (NADP+) activity,molecular_function
76121,GO:0046555,Catalysis of the deacetylation of xylans and xylo-oligosaccharides.,acetylxylan esterase activity,molecular_function
76122,GO:0046556,Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.,alpha-L-arabinofuranosidase activity,molecular_function
76123,GO:0046557,Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.,"glucan endo-1,6-beta-glucosidase activity",molecular_function
76124,GO:0046558,Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.,"arabinan endo-1,5-alpha-L-arabinosidase activity",molecular_function
76125,GO:0046559,Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.,alpha-glucuronidase activity,molecular_function
76126,GO:0046562,"Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.",beta-D-glucose oxidase activity,molecular_function
76127,GO:0046564,Catalysis of the reaction: H+ + oxalate = CO2 + formate.,oxalate decarboxylase activity,molecular_function
76128,GO:0046565,"Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.",3-dehydroshikimate dehydratase activity,molecular_function
76129,GO:0046567,Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate.,aphidicolan-16 beta-ol synthase activity,molecular_function
76130,GO:0046568,Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.,3-methylbutanal reductase [NAD(P)H] activity,molecular_function
76131,GO:0046569,Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2.,glyoxal oxidase activity,molecular_function
76132,GO:0046570,"Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O.",methylthioribulose 1-phosphate dehydratase activity,molecular_function
76133,GO:0046572,Catalysis of the reaction: (2S-3S)-versiconal hemiacetal = versicolorin B + H2O.,versicolorin B synthase activity,molecular_function
76134,GO:0046573,Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.,lactonohydrolase activity,molecular_function
76135,GO:0046574,"Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.",glucuronidase activity,molecular_function
76136,GO:0046575,Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.,rhamnogalacturonan acetylesterase activity,molecular_function
76137,GO:0046576,"Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.",rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity,molecular_function
76138,GO:0046577,Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.,long-chain-alcohol oxidase activity,molecular_function
76139,GO:0046578,"Any process that modulates the frequency, rate or extent of Ras protein signal transduction.",regulation of Ras protein signal transduction,biological_process
76140,GO:0046579,"Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.",positive regulation of Ras protein signal transduction,biological_process
76141,GO:0046580,"Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.",negative regulation of Ras protein signal transduction,biological_process
76142,GO:0046581,An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.,intercellular canaliculus,cellular_component
76143,GO:0046583,Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.,monoatomic cation efflux transmembrane transporter activity,molecular_function
76144,GO:0046585,"The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.",enniatin biosynthetic process,biological_process
76145,GO:0046586,"Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.",regulation of calcium-dependent cell-cell adhesion,biological_process
76146,GO:0046587,"Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.",positive regulation of calcium-dependent cell-cell adhesion,biological_process
76147,GO:0046588,"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.",negative regulation of calcium-dependent cell-cell adhesion,biological_process
76148,GO:0046589,"Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.",ribonuclease T1 activity,molecular_function
76149,GO:0046592,Catalysis of the oxidative degradation or interconversion of polyamines.,polyamine oxidase activity,molecular_function
76150,GO:0046593,Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde.,mandelonitrile lyase activity,molecular_function
76151,GO:0046594,The process of maintaining mRNA in a specific location in the germ plasm.,maintenance of germ plasm mRNA location,biological_process
76152,GO:0046595,Any process that results in the directed movement of mRNA to the germ plasm.,establishment of germ plasm mRNA localization,biological_process
76153,GO:0046596,"Any process that modulates the frequency, rate or extent of the viral entry into the host cell.",regulation of viral entry into host cell,biological_process
76154,GO:0046597,A process in which a host inhibits or disrupts the entry of a symbiont into a host cell.,host-mediated suppression of symbiont invasion,biological_process
76155,GO:0046598,"Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.",positive regulation of viral entry into host cell,biological_process
76156,GO:0046599,"Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.",regulation of centriole replication,biological_process
76157,GO:0046600,"Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.",negative regulation of centriole replication,biological_process
76158,GO:0046601,"Any process that activates or increases the frequency, rate or extent of centriole replication.",positive regulation of centriole replication,biological_process
76159,GO:0046602,"Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.",regulation of mitotic centrosome separation,biological_process
76160,GO:0046603,"Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.",negative regulation of mitotic centrosome separation,biological_process
76161,GO:0046604,"Any process that activates or increases the frequency, rate or extent of centrosome separation.",positive regulation of mitotic centrosome separation,biological_process
76162,GO:0046605,"Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.",regulation of centrosome cycle,biological_process
76163,GO:0046606,"Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.",negative regulation of centrosome cycle,biological_process
76164,GO:0046607,"Any process that activates or increases the frequency, rate or extent of the centrosome cycle.",positive regulation of centrosome cycle,biological_process
76165,GO:0046608,Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.,carotenoid isomerase activity,molecular_function
76166,GO:0046610,The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.,"lysosomal proton-transporting V-type ATPase, V0 domain",cellular_component
76167,GO:0046611,"A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen.",lysosomal proton-transporting V-type ATPase complex,cellular_component
76168,GO:0046612,The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.,"lysosomal proton-transporting V-type ATPase, V1 domain",cellular_component
76169,GO:0046618,"The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",xenobiotic export from cell,biological_process
76170,GO:0046619,"Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.",lens placode formation involved in camera-type eye formation,biological_process
76171,GO:0046620,"Any process that modulates the frequency, rate or extent of growth of an organ of an organism.",regulation of organ growth,biological_process
76172,GO:0046621,"Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.",negative regulation of organ growth,biological_process
76173,GO:0046622,"Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.",positive regulation of organ growth,biological_process
76174,GO:0046623,"Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",sphingolipid floppase activity,molecular_function
76175,GO:0046624,"Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",sphingolipid intramembrane carrier activity,molecular_function
76176,GO:0046625,"Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",sphingolipid binding,molecular_function
76177,GO:0046626,"Any process that modulates the frequency, rate or extent of insulin receptor signaling.",regulation of insulin receptor signaling pathway,biological_process
76178,GO:0046627,"Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.",negative regulation of insulin receptor signaling pathway,biological_process
76179,GO:0046628,"Any process that increases the frequency, rate or extent of insulin receptor signaling.",positive regulation of insulin receptor signaling pathway,biological_process
76180,GO:0046629,"The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",gamma-delta T cell activation,biological_process
76181,GO:0046630,The expansion of a gamma-delta T cell population by cell division.,gamma-delta T cell proliferation,biological_process
76182,GO:0046631,"The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",alpha-beta T cell activation,biological_process
76183,GO:0046632,The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.,alpha-beta T cell differentiation,biological_process
76184,GO:0046633,The expansion of an alpha-beta T cell population by cell division.,alpha-beta T cell proliferation,biological_process
76185,GO:0046634,"Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.",regulation of alpha-beta T cell activation,biological_process
76186,GO:0046635,"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.",positive regulation of alpha-beta T cell activation,biological_process
76187,GO:0046636,"Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.",negative regulation of alpha-beta T cell activation,biological_process
76188,GO:0046637,"Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation.",regulation of alpha-beta T cell differentiation,biological_process
76189,GO:0046638,"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.",positive regulation of alpha-beta T cell differentiation,biological_process
76190,GO:0046639,"Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.",negative regulation of alpha-beta T cell differentiation,biological_process
76191,GO:0046640,"Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.",regulation of alpha-beta T cell proliferation,biological_process
76192,GO:0046641,"Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.",positive regulation of alpha-beta T cell proliferation,biological_process
76193,GO:0046642,"Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.",negative regulation of alpha-beta T cell proliferation,biological_process
76194,GO:0046643,"Any process that modulates the frequency, rate or extent of gamma-delta T cell activation.",regulation of gamma-delta T cell activation,biological_process
76195,GO:0046644,"Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.",negative regulation of gamma-delta T cell activation,biological_process
76196,GO:0046645,"Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.",positive regulation of gamma-delta T cell activation,biological_process
76197,GO:0046646,"Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation.",regulation of gamma-delta T cell proliferation,biological_process
76198,GO:0046647,"Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.",negative regulation of gamma-delta T cell proliferation,biological_process
76199,GO:0046648,"Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.",positive regulation of gamma-delta T cell proliferation,biological_process
76200,GO:0046649,"A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.",lymphocyte activation,biological_process
76201,GO:0046651,The expansion of a lymphocyte population by cell division.,lymphocyte proliferation,biological_process
76202,GO:0046653,"The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.",tetrahydrofolate metabolic process,biological_process
76203,GO:0046654,"The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.",tetrahydrofolate biosynthetic process,biological_process
76204,GO:0046655,"The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.",folic acid metabolic process,biological_process
76205,GO:0046656,"The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.",folic acid biosynthetic process,biological_process
76206,GO:0046657,"The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.",folic acid catabolic process,biological_process
76207,GO:0046659,The action characteristic of a hormone that takes part in the digestion process.,digestive hormone activity,molecular_function
76208,GO:0046660,The establishment of the sex of a female organism by physical differentiation.,female sex differentiation,biological_process
76209,GO:0046661,The establishment of the sex of a male organism by physical differentiation.,male sex differentiation,biological_process
76210,GO:0046662,"Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.",regulation of egg-laying behavior,biological_process
76211,GO:0046663,"The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure.","dorsal closure, leading edge cell differentiation",biological_process
76212,GO:0046664,"The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.","dorsal closure, amnioserosa morphology change",biological_process
76213,GO:0046665,"Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.",amnioserosa maintenance,biological_process
76214,GO:0046666,Programmed cell death that occurs in the developing retina.,retinal cell programmed cell death,biological_process
76215,GO:0046667,"Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.",compound eye retinal cell programmed cell death,biological_process
76216,GO:0046668,"Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.",regulation of retinal cell programmed cell death,biological_process
76217,GO:0046669,"Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.",regulation of compound eye retinal cell programmed cell death,biological_process
76218,GO:0046670,"Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.",positive regulation of retinal cell programmed cell death,biological_process
76219,GO:0046671,"Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.",negative regulation of retinal cell programmed cell death,biological_process
76220,GO:0046672,"Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.",positive regulation of compound eye retinal cell programmed cell death,biological_process
76221,GO:0046673,"Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.",negative regulation of compound eye retinal cell programmed cell death,biological_process
76222,GO:0046676,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.",negative regulation of insulin secretion,biological_process
76223,GO:0046677,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.",response to antibiotic,biological_process
76224,GO:0046678,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative ...",response to bacteriocin,biological_process
76225,GO:0046679,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.",response to streptomycin,biological_process
76226,GO:0046680,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.",response to DDT,biological_process
76227,GO:0046681,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.",response to carbamate,biological_process
76228,GO:0046682,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring.",response to cyclodiene,biological_process
76229,GO:0046683,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.",response to organophosphorus,biological_process
76230,GO:0046684,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.",response to pyrethroid,biological_process
76231,GO:0046685,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.",response to arsenic-containing substance,biological_process
76232,GO:0046686,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.",response to cadmium ion,biological_process
76233,GO:0046687,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.",response to chromate,biological_process
76234,GO:0046688,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.",response to copper ion,biological_process
76235,GO:0046689,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.",response to mercury ion,biological_process
76236,GO:0046690,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.",response to tellurium ion,biological_process
76237,GO:0046691,"An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.",intracellular canaliculus,cellular_component
76238,GO:0046692,Any process that contributes to the success of sperm fertilization in multiply-mated females.,sperm competition,biological_process
76239,GO:0046693,The retention of sperm by a female following mating.,sperm storage,biological_process
76240,GO:0046694,The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.,sperm incapacitation,biological_process
76241,GO:0046695,"A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.",SLIK (SAGA-like) complex,cellular_component
76242,GO:0046696,"A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.",lipopolysaccharide receptor complex,cellular_component
76243,GO:0046697,"The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.",decidualization,biological_process
76244,GO:0046701,"The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects.",insecticide catabolic process,biological_process
76245,GO:0046702,"Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside.",galactoside 6-L-fucosyltransferase activity,molecular_function
76246,GO:0046703,Binding to a lectin-like natural killer cell receptor.,natural killer cell lectin-like receptor binding,molecular_function
76247,GO:0046704,"The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.",CDP metabolic process,biological_process
76248,GO:0046705,"The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.",CDP biosynthetic process,biological_process
76249,GO:0046706,"The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.",CDP catabolic process,biological_process
76250,GO:0046707,"The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.",IDP metabolic process,biological_process
76251,GO:0046708,"The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate.",IDP biosynthetic process,biological_process
76252,GO:0046709,"The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.",IDP catabolic process,biological_process
76253,GO:0046710,"The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.",GDP metabolic process,biological_process
76254,GO:0046711,"The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.",GDP biosynthetic process,biological_process
76255,GO:0046712,"The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.",GDP catabolic process,biological_process
76256,GO:0046713,"The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.",borate transport,biological_process
76257,GO:0046714,"Binding to borate, the anion (BO3)3-.",borate binding,molecular_function
76258,GO:0046716,The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.,muscle cell cellular homeostasis,biological_process
76259,GO:0046717,The controlled release of acid by a cell or a tissue.,acid secretion,biological_process
76260,GO:0046718,The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell.,symbiont entry into host cell,biological_process
76261,GO:0046719,Any virus-mediated process that modulates the levels of viral proteins in a cell.,regulation by virus of viral protein levels in host cell,biological_process
76262,GO:0046720,"The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue.",citric acid secretion,biological_process
76263,GO:0046721,"The controlled release of formic acid, HCOOH, by a cell or a tissue.",formic acid secretion,biological_process
76264,GO:0046722,"The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue.",lactic acid secretion,biological_process
76265,GO:0046723,"The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue.",malic acid secretion,biological_process
76266,GO:0046724,"The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.",oxalic acid secretion,biological_process
76267,GO:0046725,Any process where the infecting virus reduces the levels of viral proteins in a cell.,negative regulation by virus of viral protein levels in host cell,biological_process
76268,GO:0046726,Any process where the infecting virus increases the levels of viral proteins in a cell.,positive regulation by virus of viral protein levels in host cell,biological_process
76269,GO:0046727,Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.,capsomere,cellular_component
76270,GO:0046729,A stable empty viral capsid produced during the assembly of viruses.,viral procapsid,cellular_component
76271,GO:0046739,The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).,transport of virus in multicellular host,biological_process
76272,GO:0046740,The transport of a virus between adjacent cells in a multicellular organism.,"transport of virus in host, cell to cell",biological_process
76273,GO:0046741,The transport of a virus between tissues in a multicellular organism.,"transport of virus in host, tissue to tissue",biological_process
76274,GO:0046745,"The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.",viral capsid secondary envelopment,biological_process
76275,GO:0046753,The exit of a viral particle from a host cell that does not involve cell lysis.,non-lytic viral release,biological_process
76276,GO:0046754,The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle.,viral exocytosis,biological_process
76277,GO:0046755,"A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.",viral budding,biological_process
76278,GO:0046760,A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.,viral budding from Golgi membrane,biological_process
76279,GO:0046761,A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles.,viral budding from plasma membrane,biological_process
76280,GO:0046762,A viral budding that starts with formation of a membrane curvature in the host ER membrane.,viral budding from endoplasmic reticulum membrane,biological_process
76281,GO:0046765,A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.,viral budding from nuclear membrane,biological_process
76282,GO:0046771,"The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.",viral budding from inner nuclear membrane,biological_process
76283,GO:0046772,"The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.",viral budding from outer nuclear membrane,biological_process
76284,GO:0046773,A process in which a symbiont inhibits or disrupts translation termination of host mRNAs. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host translation termination,biological_process
76285,GO:0046776,"A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, some viruses can prevent presentation of their antigens at the cell...",symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I,biological_process
76286,GO:0046777,"The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).",protein autophosphorylation,biological_process
76287,GO:0046780,"A process in which a symbiont inhibits or disrupts the splicing of host mRNA, thus interfering with normal host protein production. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host mRNA splicing,biological_process
76288,GO:0046782,"Any process that modulates the frequency, rate or extent of the transcription of the viral genome.",regulation of viral transcription,biological_process
76289,GO:0046784,The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.,viral mRNA export from host cell nucleus,biological_process
76290,GO:0046785,The addition of tubulin heterodimers to one or both ends of a microtubule.,microtubule polymerization,biological_process
76291,GO:0046786,The process of organizing and assembling viral replication proteins in preparation for viral replication.,viral replication complex formation and maintenance,biological_process
76292,GO:0046787,The process of restoring viral DNA after damage or errors in replication.,viral DNA repair,biological_process
76293,GO:0046789,Binding to a receptor on the host cell surface.,host cell surface receptor binding,molecular_function
76294,GO:0046790,"Binding to a virion, either by binding to components of the capsid or the viral envelope.",virion binding,molecular_function
76295,GO:0046794,"The directed movement of a virus, or part of a virus, into, out of, or within a host cell.",transport of virus,biological_process
76296,GO:0046797,"The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.",viral procapsid maturation,biological_process
76297,GO:0046798,A multimeric ring of proteins through which the DNA enters and exits the viral capsid.,viral portal complex,cellular_component
76298,GO:0046802,"The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.",exit of virus from host cell nucleus by nuclear egress,biological_process
76299,GO:0046806,A complex of proteins that form a scaffold around which the viral capsid is constructed.,viral scaffold,cellular_component
76300,GO:0046807,The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.,viral scaffold assembly and maintenance,biological_process
76301,GO:0046809,Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.,replication compartment,cellular_component
76302,GO:0046810,Binding to the extracellular matrix of a host cell.,host cell extracellular matrix binding,molecular_function
76303,GO:0046811,"Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.",histone deacetylase inhibitor activity,molecular_function
76304,GO:0046812,Binding to the surface of a host cell.,host cell surface binding,molecular_function
76305,GO:0046813,The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.,receptor-mediated virion attachment to host cell,biological_process
76306,GO:0046814,The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.,coreceptor-mediated virion attachment to host cell,biological_process
76307,GO:0046816,A vesicle used to transport the partial or complete virion between cellular compartments.,virion transport vesicle,cellular_component
76308,GO:0046817,Interacts with chemokine receptors to reduce the action of a chemokine.,chemokine receptor antagonist activity,molecular_function
76309,GO:0046818,A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.,dense nuclear body,cellular_component
76310,GO:0046819,"The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.",protein secretion by the type V secretion system,biological_process
76311,GO:0046820,"Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.",aminodeoxychorismate synthase activity,molecular_function
76312,GO:0046821,DNA structures that are not part of a chromosome.,extrachromosomal DNA,cellular_component
76313,GO:0046822,"Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.",regulation of nucleocytoplasmic transport,biological_process
76314,GO:0046823,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.",negative regulation of nucleocytoplasmic transport,biological_process
76315,GO:0046824,"Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.",positive regulation of nucleocytoplasmic transport,biological_process
76316,GO:0046825,"Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.",regulation of protein export from nucleus,biological_process
76317,GO:0046826,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.",negative regulation of protein export from nucleus,biological_process
76318,GO:0046827,"Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.",positive regulation of protein export from nucleus,biological_process
76319,GO:0046828,"Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.",regulation of RNA import into nucleus,biological_process
76320,GO:0046829,"Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.",negative regulation of RNA import into nucleus,biological_process
76321,GO:0046830,"Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.",positive regulation of RNA import into nucleus,biological_process
76322,GO:0046831,"Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.",regulation of RNA export from nucleus,biological_process
76323,GO:0046832,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.",negative regulation of RNA export from nucleus,biological_process
76324,GO:0046833,"Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.",positive regulation of RNA export from nucleus,biological_process
76325,GO:0046834,"The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.",lipid phosphorylation,biological_process
76326,GO:0046835,"The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.",carbohydrate phosphorylation,biological_process
76327,GO:0046836,"The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycolipid transport,biological_process
76328,GO:0046839,"The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.",phospholipid dephosphorylation,biological_process
76329,GO:0046842,The chemical reactions and pathways resulting in the formation of trisporic acid.,trisporic acid biosynthetic process,biological_process
76330,GO:0046843,"Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.",dorsal appendage formation,biological_process
76331,GO:0046844,"Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization.",chorion micropyle formation,biological_process
76332,GO:0046845,"Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.","branched duct epithelial cell fate determination, open tracheal system",biological_process
76333,GO:0046847,"The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.",filopodium assembly,biological_process
76334,GO:0046848,"Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.",hydroxyapatite binding,molecular_function
76335,GO:0046849,"The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic b...",bone remodeling,biological_process
76336,GO:0046850,"Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.",regulation of bone remodeling,biological_process
76337,GO:0046851,"Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.",negative regulation of bone remodeling,biological_process
76338,GO:0046852,"Any process that activates or increases the frequency, rate or extent of bone remodeling.",positive regulation of bone remodeling,biological_process
76339,GO:0046854,The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.,phosphatidylinositol phosphate biosynthetic process,biological_process
76340,GO:0046856,The process of removing one or more phosphate groups from a phosphatidylinositol.,phosphatidylinositol dephosphorylation,biological_process
76341,GO:0046857,"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.","oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor",molecular_function
76342,GO:0046858,"A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.",chlorosome,cellular_component
76343,GO:0046859,The lipid bilayer surrounding a hydrogenosome.,hydrogenosomal membrane,cellular_component
76344,GO:0046860,The lipid bilayer surrounding a glycosome.,glycosome membrane,cellular_component
76345,GO:0046861,The lipid bilayer surrounding a glyoxysome.,glyoxysomal membrane,cellular_component
76346,GO:0046862,Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope.,chromoplast membrane,cellular_component
76347,GO:0046863,"Binds to and iincreases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.","ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity",molecular_function
76348,GO:0046864,"The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.",isoprenoid transport,biological_process
76349,GO:0046865,"The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.",terpenoid transport,biological_process
76350,GO:0046866,"The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.",tetraterpenoid transport,biological_process
76351,GO:0046867,"The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.",carotenoid transport,biological_process
76352,GO:0046868,"An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins.",mesosome,cellular_component
76353,GO:0046870,Binding to a cadmium ion (Cd).,cadmium ion binding,molecular_function
76354,GO:0046871,"Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.",N-acetylgalactosamine binding,molecular_function
76355,GO:0046872,Binding to a metal ion.,metal ion binding,molecular_function
76356,GO:0046873,Enables the transfer of metal ions from one side of a membrane to the other.,metal ion transmembrane transporter activity,molecular_function
76357,GO:0046874,"The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.",quinolinate metabolic process,biological_process
76358,GO:0046875,Binding to an ephrin receptor.,ephrin receptor binding,molecular_function
76359,GO:0046876,"Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).","3,4-didehydroretinal binding",molecular_function
76360,GO:0046877,"Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.",regulation of saliva secretion,biological_process
76361,GO:0046878,"Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.",positive regulation of saliva secretion,biological_process
76362,GO:0046879,"The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.",hormone secretion,biological_process
76363,GO:0046880,"Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.",regulation of follicle-stimulating hormone secretion,biological_process
76364,GO:0046881,"Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.",positive regulation of follicle-stimulating hormone secretion,biological_process
76365,GO:0046882,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.",negative regulation of follicle-stimulating hormone secretion,biological_process
76366,GO:0046883,"Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.",regulation of hormone secretion,biological_process
76367,GO:0046884,"The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.",follicle-stimulating hormone secretion,biological_process
76368,GO:0046885,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.",regulation of hormone biosynthetic process,biological_process
76369,GO:0046886,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.",positive regulation of hormone biosynthetic process,biological_process
76370,GO:0046887,"Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.",positive regulation of hormone secretion,biological_process
76371,GO:0046888,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.",negative regulation of hormone secretion,biological_process
76372,GO:0046889,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.",positive regulation of lipid biosynthetic process,biological_process
76373,GO:0046890,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.",regulation of lipid biosynthetic process,biological_process
76374,GO:0046898,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.",response to cycloheximide,biological_process
76375,GO:0046899,Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.,nucleoside triphosphate adenylate kinase activity,molecular_function
76376,GO:0046900,"The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.",tetrahydrofolylpolyglutamate metabolic process,biological_process
76377,GO:0046901,"The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.",tetrahydrofolylpolyglutamate biosynthetic process,biological_process
76378,GO:0046902,"Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.",regulation of mitochondrial membrane permeability,biological_process
76379,GO:0046903,The controlled release of a substance by a cell or a tissue.,secretion,biological_process
76380,GO:0046904,"Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.",calcium oxalate binding,molecular_function
76381,GO:0046905,Catalysis of the reaction: 2 geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate.,15-cis-phytoene synthase activity,molecular_function
76382,GO:0046906,"Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.",tetrapyrrole binding,molecular_function
76383,GO:0046907,The directed movement of substances within a cell.,intracellular transport,biological_process
76384,GO:0046910,"Binds to and stops, prevents or reduces the activity of pectinesterase.",pectinesterase inhibitor activity,molecular_function
76385,GO:0046911,The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.,metal chelating activity,molecular_function
76386,GO:0046912,"Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.","acyltransferase activity, acyl groups converted into alkyl on transfer",molecular_function
76387,GO:0046914,"Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.",transition metal ion binding,molecular_function
76388,GO:0046915,"Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.",transition metal ion transmembrane transporter activity,molecular_function
76389,GO:0046917,Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.,triphosphoribosyl-dephospho-CoA synthase activity,molecular_function
76390,GO:0046919,Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.,pyruvyltransferase activity,molecular_function
76391,GO:0046920,Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.,alpha-(1->3)-fucosyltransferase activity,molecular_function
76392,GO:0046921,Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.,alpha-(1->6)-fucosyltransferase activity,molecular_function
76393,GO:0046922,Catalysis of the transfer of an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor.,peptide-O-fucosyltransferase activity,molecular_function
76394,GO:0046923,"Binding to an endoplasmic reticulum (ER) retention sequence, a short stretch of amino acids found in a protein that acts as a signal to retain the protein within the ER.",ER lumen protein retrieval receptor activity,molecular_function
76395,GO:0046928,"Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.",regulation of neurotransmitter secretion,biological_process
76396,GO:0046929,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.",negative regulation of neurotransmitter secretion,biological_process
76397,GO:0046930,A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.,pore complex,cellular_component
76398,GO:0046931,"The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.",pore complex assembly,biological_process
76399,GO:0046932,Enables the transfer of a solute or solutes from one side of a membrane to the other by a rotational mechanism according to the reaction: 4 Na+(out) + ADP + phosphate + H+ => 4 Na+(in) + ATP + H2O.,"sodium-transporting ATP synthase activity, rotational mechanism",molecular_function
76400,GO:0046933,Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + phosphate + 5 H+(out) => ATP + H2O + 4 H+(in).,"proton-transporting ATP synthase activity, rotational mechanism",molecular_function
76401,GO:0046934,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+.","1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity",molecular_function
76402,GO:0046935,Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.,1-phosphatidylinositol-3-kinase regulator activity,molecular_function
76403,GO:0046936,Catalysis of the reaction: 2'-deoxyadenosine + H+ + H2O = 2'-deoxyinosine + NH4+.,2'-deoxyadenosine deaminase activity,molecular_function
76404,GO:0046937,"The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.",phytochelatin metabolic process,biological_process
76405,GO:0046938,"The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.",phytochelatin biosynthetic process,biological_process
76406,GO:0046940,The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.,nucleoside monophosphate phosphorylation,biological_process
76407,GO:0046941,Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.,azetidine-2-carboxylic acid acetyltransferase activity,molecular_function
76408,GO:0046942,"The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).",carboxylic acid transport,biological_process
76409,GO:0046943,Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).,carboxylic acid transmembrane transporter activity,molecular_function
76410,GO:0046944,The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.,protein carbamoylation,biological_process
76411,GO:0046949,"The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.",fatty-acyl-CoA biosynthetic process,biological_process
76412,GO:0046951,"The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.",ketone body biosynthetic process,biological_process
76413,GO:0046952,"The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.",ketone body catabolic process,biological_process
76414,GO:0046956,The directed movement of a cell or organism towards a source of light.,positive phototaxis,biological_process
76415,GO:0046957,The directed movement of a cell or organism away from a source of light.,negative phototaxis,biological_process
76416,GO:0046958,"A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.",nonassociative learning,biological_process
76417,GO:0046959,A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.,habituation,biological_process
76418,GO:0046960,"An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.",sensitization,biological_process
76419,GO:0046961,Enables the transfer of protons from one side of a membrane to the other by a rotational mechanism according to the reaction: ATP + H2O + 4 H+(in) => ADP + phosphate + 5 H+(out).,"proton-transporting ATPase activity, rotational mechanism",molecular_function
76420,GO:0046962,Enables the transfer of a solute or solutes from one side of a membrane to the other by a rotational mechanism according to the reaction: 4 Na+(in) + ATP + H2O => 4 Na+(out) + ADP + phosphate + H+.,"sodium-transporting ATPase activity, rotational mechanism",molecular_function
76421,GO:0046963,"The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",3'-phosphoadenosine 5'-phosphosulfate transport,biological_process
76422,GO:0046964,"Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.",3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity,molecular_function
76423,GO:0046965,Binding to a nuclear retinoid X receptor.,nuclear retinoid X receptor binding,molecular_function
76424,GO:0046966,Binding to a nuclear thyroid hormone receptor.,nuclear thyroid hormone receptor binding,molecular_function
76425,GO:0046967,The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.,cytosol to endoplasmic reticulum transport,biological_process
76426,GO:0046968,"The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.",peptide antigen transport,biological_process
76427,GO:0046969,"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + NAD+ + H2O = histone H3 L-lysine (position 9) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K9 to NAD, producing nicotinamide.","histone H3K9 deacetylase activity, NAD-dependent",molecular_function
76428,GO:0046970,"Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + NAD+ + H2O = histone H4 L-lysine (position 16) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H4K16 to NAD, producing nicotinamide.","histone H4K16 deacetylase activity, NAD-dependent",molecular_function
76429,GO:0046972,Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.,histone H4K16 acetyltransferase activity,molecular_function
76430,GO:0046974,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of up to three methyl groups to the lysine residue at position 9 of the histone H3 protein.,histone H3K9 methyltransferase activity,molecular_function
76431,GO:0046975,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group to the lysine residue at position 36 of the histone H3 protein.,histone H3K36 methyltransferase activity,molecular_function
76432,GO:0046976,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group to the lysine residue at position 27 of the histone H3 protein.,histone H3K27 methyltransferase activity,molecular_function
76433,GO:0046977,"Binding to TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2.",TAP binding,molecular_function
76434,GO:0046978,Binding to the TAP1 subunit of TAP (transporter associated with antigen processing) protein.,TAP1 binding,molecular_function
76435,GO:0046979,Binding to the TAP2 subunit of TAP (transporter associated with antigen processing) protein.,TAP2 binding,molecular_function
76436,GO:0046980,"Binding to tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.",tapasin binding,molecular_function
76437,GO:0046981,"Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.","beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity",molecular_function
76438,GO:0046982,Binding to a nonidentical protein to form a heterodimer.,protein heterodimerization activity,molecular_function
76439,GO:0046983,"The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.",protein dimerization activity,molecular_function
76440,GO:0046984,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.",regulation of hemoglobin biosynthetic process,biological_process
76441,GO:0046985,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.",positive regulation of hemoglobin biosynthetic process,biological_process
76442,GO:0046986,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.",negative regulation of hemoglobin biosynthetic process,biological_process
76443,GO:0046987,"Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).","N-acetyllactosamine beta-1,3-glucuronosyltransferase activity",molecular_function
76444,GO:0046988,"Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.","asioloorosomucoid beta-1,3-glucuronosyltransferase activity",molecular_function
76445,GO:0046989,"Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.","galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity",molecular_function
76446,GO:0046990,Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.,N-hydroxyarylamine O-acetyltransferase activity,molecular_function
76447,GO:0046992,Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.,"oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond",molecular_function
76448,GO:0046993,Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.,"oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor",molecular_function
76449,GO:0046994,Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound.,"oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor",molecular_function
76450,GO:0046995,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.","oxidoreductase activity, acting on hydrogen as donor, with other known acceptors",molecular_function
76451,GO:0046997,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.,"oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor",molecular_function
76452,GO:0046998,"Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD+ = (S)-usnate + 2 H+ + NADH.",(S)-usnate reductase activity,molecular_function
76453,GO:0047000,"Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H+ + NADPH.",2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity,molecular_function
76454,GO:0047001,"Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.",2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity,molecular_function
76455,GO:0047002,Catalysis of the reaction: L-arabinitol + NAD+ = L-ribulose + H+ + NADH.,L-arabinitol 2-dehydrogenase activity,molecular_function
76456,GO:0047003,Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + H+ + NADPH.,dTDP-6-deoxy-L-talose 4-dehydrogenase activity,molecular_function
76457,GO:0047004,Catalysis of the reaction: H2O + 2 NAD+ + UDP-N-acetyl-alpha-D-glucosamine = 3 H+ + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate.,UDP-N-acetylglucosamine 6-dehydrogenase activity,molecular_function
76458,GO:0047006,"Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.","17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity",molecular_function
76459,GO:0047007,Catalysis of the reaction: NAD+ + pregnan-21-ol = H+ + NADH + pregnan-21-al.,pregnan-21-ol dehydrogenase (NAD+) activity,molecular_function
76460,GO:0047008,Catalysis of the reaction: NADP+ + pregnan-21-ol = H+ + NADPH + pregnan-21-al.,pregnan-21-ol dehydrogenase (NADP+) activity,molecular_function
76461,GO:0047009,"Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.",3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity,molecular_function
76462,GO:0047010,"Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H+ + NADH.",hydroxycyclohexanecarboxylate dehydrogenase activity,molecular_function
76463,GO:0047011,Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.,2-dehydropantolactone reductase (A-specific) activity,molecular_function
76464,GO:0047013,"Catalysis of the reaction: cholate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + H+ + NADPH.",cholate 12-alpha dehydrogenase (NADP+) activity,molecular_function
76465,GO:0047014,Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + H+ + NADPH.,glycerol-3-phosphate 1-dehydrogenase (NADP+) activity,molecular_function
76466,GO:0047015,Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.,3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity,molecular_function
76467,GO:0047016,Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.,"cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",molecular_function
76468,GO:0047017,Catalysis of the reaction: NADP+ + prostaglandin F2alpha = H+ + NADPH + prostaglandin D2.,prostaglandin F synthase activity,molecular_function
76469,GO:0047018,Catalysis of the reaction: indole-3-ethanol + NAD+ = (indol-3-yl)acetaldehyde + H+ + NADH.,indole-3-acetaldehyde reductase (NADH) activity,molecular_function
76470,GO:0047019,Catalysis of the reaction: indole-3-ethanol + NADP+ = (indol-3-yl)acetaldehyde + H+ + NADPH.,indole-3-acetaldehyde reductase (NADPH) activity,molecular_function
76471,GO:0047020,"Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.",15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity,molecular_function
76472,GO:0047021,Catalysis of the reaction: NADP+ + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H+ + NADPH.,15-hydroxyprostaglandin dehydrogenase (NADP+) activity,molecular_function
76473,GO:0047022,Catalysis of the reaction: a 7-beta-hydroxysteroid + NADP+ = a 7-oxosteroid + NADPH + H+.,7-beta-hydroxysteroid dehydrogenase (NADP+) activity,molecular_function
76474,GO:0047023,"Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.",androsterone dehydrogenase [NAD(P)+] activity,molecular_function
76475,GO:0047024,"Catalysis of the reaction: 5-alpha-androstane-3-beta,17-beta-diol + NADP+ = 17-beta-hydroxy-5-alpha-androstan-3-one + H+ + NADPH.","5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity",molecular_function
76476,GO:0047025,Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].,3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity,molecular_function
76477,GO:0047027,"Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ = benzyl 2-methyl-3-oxobutanoate + H+ + NADPH.",benzyl-2-methyl-hydroxybutyrate dehydrogenase activity,molecular_function
76478,GO:0047028,"Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.",6-pyruvoyltetrahydropterin 2'-reductase activity,molecular_function
76479,GO:0047029,Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.,(R)-4-hydroxyphenyllactate dehydrogenase (NADP+) activity,molecular_function
76480,GO:0047030,Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + H+ + NADH.,4-hydroxycyclohexanecarboxylate dehydrogenase activity,molecular_function
76481,GO:0047031,"Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + H+ + NADPH.",diethyl 2-methyl-3-oxosuccinate reductase activity,molecular_function
76482,GO:0047032,Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + H+ + NADPH.,3-alpha-hydroxyglycyrrhetinate dehydrogenase activity,molecular_function
76483,GO:0047033,Catalysis of the reaction: NADP+ + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H+ + NADPH.,15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity,molecular_function
76484,GO:0047034,"Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.",15-hydroxyicosatetraenoate dehydrogenase activity,molecular_function
76485,GO:0047035,"Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.",testosterone dehydrogenase (NAD+) activity,molecular_function
76486,GO:0047036,Catalysis of the reaction: codeine + NADP+ = codeinone + H+ + NADPH.,codeinone reductase (NADPH) activity,molecular_function
76487,GO:0047037,Catalysis of the reaction: (7S)-salutaridinol + NADP+ = H+ + NADPH + salutaridine.,salutaridine reductase (NADPH) activity,molecular_function
76488,GO:0047038,Catalysis of the reaction: D-arabinitol + NAD+ = D-ribulose + H+ + NADH.,D-arabinitol 2-dehydrogenase activity,molecular_function
76489,GO:0047039,"Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.",tetrahydroxynaphthalene reductase activity,molecular_function
76490,GO:0047040,"Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP+ = biopterin + 2 H+ + 2 NADPH.",pteridine reductase activity,molecular_function
76491,GO:0047041,Catalysis of the reaction: (S)-carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.,(S)-carnitine 3-dehydrogenase activity,molecular_function
76492,GO:0047043,Catalysis of the reaction: lithocholate + NAD+ = 3-oxo-5beta-cholanate + H+ + NADH.,3-alpha-hydroxycholanate dehydrogenase activity,molecular_function
76493,GO:0047044,"Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.","androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity",molecular_function
76494,GO:0047045,"Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.",testosterone dehydrogenase (NADP+) activity,molecular_function
76495,GO:0047046,Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.,homoisocitrate dehydrogenase activity,molecular_function
76496,GO:0047047,Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.,oxaloglycolate reductase (decarboxylating) activity,molecular_function
76497,GO:0047048,Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP+ = 3-hydroxybenzaldehyde + H+ + NADPH.,3-hydroxybenzyl-alcohol dehydrogenase activity,molecular_function
76498,GO:0047049,Catalysis of the reaction: (R)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.,(R)-2-hydroxy-fatty acid dehydrogenase (NAD+) activity,molecular_function
76499,GO:0047050,Catalysis of the reaction: (S)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.,(S)-2-hydroxy-fatty acid dehydrogenase activity,molecular_function
76500,GO:0047051,Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.,D-lactate dehydrogenase (cytochrome c-553) activity,molecular_function
76501,GO:0047052,Catalysis of the reaction: (S)-cheilanthifoline + reduced [NADPH--hemoprotein reductase] + O2 = (S)-stylopine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+.,(S)-stylopine synthase activity,molecular_function
76502,GO:0047053,Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 = (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O.,(S)-cheilanthifoline synthase activity,molecular_function
76503,GO:0047054,Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 = berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.,berbamunine synthase activity,molecular_function
76504,GO:0047055,Catalysis of the reaction: (R)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 = salutaridine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+.,salutaridine synthase activity,molecular_function
76505,GO:0047056,Catalysis of the reaction: (S)-tetrahydrocolumbamine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-canadine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+.,(S)-canadine synthase activity,molecular_function
76506,GO:0047057,Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues.,vitamin-K-epoxide reductase (warfarin-sensitive) activity,molecular_function
76507,GO:0047058,"Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.",vitamin-K-epoxide reductase (warfarin-insensitive) activity,molecular_function
76508,GO:0047059,Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.,polyvinyl alcohol dehydrogenase (cytochrome) activity,molecular_function
76509,GO:0047060,Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).,(R)-pantolactone dehydrogenase (flavin) activity,molecular_function
76510,GO:0047061,"Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.",glucose-fructose oxidoreductase activity,molecular_function
76511,GO:0047062,"Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP+ = acenaphthene-1,2-dione + 2 H+ + 2 NADPH.","trans-acenaphthene-1,2-diol dehydrogenase activity",molecular_function
76512,GO:0047064,Catalysis of the reaction: O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O.,sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity,molecular_function
76513,GO:0047065,Catalysis of the reaction: O2 + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H2O.,sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity,molecular_function
76514,GO:0047066,Catalysis of the reaction: a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O.,phospholipid-hydroperoxide glutathione peroxidase activity,molecular_function
76515,GO:0047067,Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone.,hydrogen:quinone oxidoreductase activity,molecular_function
76516,GO:0047068,"Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H+.","N5,N10-methenyltetrahydromethanopterin hydrogenase activity",molecular_function
76517,GO:0047069,"Catalysis of the reaction: 7,8-dihydroxykynurenate + O2 = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+.","7,8-dihydroxykynurenate 8,8a-dioxygenase activity",molecular_function
76518,GO:0047070,"Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.","3-carboxyethylcatechol 2,3-dioxygenase activity",molecular_function
76519,GO:0047071,"Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H+.","3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity",molecular_function
76520,GO:0047072,"Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H+.","2,3-dihydroxybenzoate 2,3-dioxygenase activity",molecular_function
76521,GO:0047073,"Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H+.","2,4'-dihydroxyacetophenone dioxygenase activity",molecular_function
76522,GO:0047074,"Catalysis of the reaction: benzene-1,2,4-triol + O2 = maleylacetate + 2 H+.","hydroxyquinol 1,2-dioxygenase activity",molecular_function
76523,GO:0047075,"Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.","2,5-dihydroxypyridine 5,6-dioxygenase activity",molecular_function
76524,GO:0047077,Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.,Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity,molecular_function
76525,GO:0047078,Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.,"3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity",molecular_function
76526,GO:0047079,"Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil.",deoxyuridine 1'-dioxygenase activity,molecular_function
76527,GO:0047080,Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = CO2 + succinate + uridine.,deoxyuridine 2'-dioxygenase activity,molecular_function
76528,GO:0047081,Catalysis of the reaction: 3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + O2 = 2-(acetamidomethylene)succinate + NAD(P)+.,3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase [NAD(P)H] activity,molecular_function
76529,GO:0047082,"Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H+ + NADPH + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.","3,9-dihydroxypterocarpan 6a-monooxygenase activity",molecular_function
76530,GO:0047083,Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.,5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity,molecular_function
76531,GO:0047084,Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.,methyltetrahydroprotoberberine 14-monooxygenase activity,molecular_function
76532,GO:0047085,Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H+ + NADPH + O2 = 4-hydroxymandelonitrile + H2O + NADP+.,hydroxyphenylacetonitrile 2-monooxygenase activity,molecular_function
76533,GO:0047086,Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.,ketosteroid monooxygenase activity,molecular_function
76534,GO:0047087,Catalysis of the reaction: O2 + protopine + reduced [NADPH--hemoprotein reductase] = 6-hydroxyprotopine + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,protopine 6-monooxygenase activity,molecular_function
76535,GO:0047088,Catalysis of the reaction: dihydrosanguinarine + H+ + NADPH + O2 = 10-hydroxydihydrosanguinarine + H2O + NADP+.,dihydrosanguinarine 10-monooxygenase activity,molecular_function
76536,GO:0047089,Catalysis of the reaction: dihydrochelirubine + H+ + NADPH + O2 = 12-hydroxydihydrochelirubine + H2O + NADP+.,dihydrochelirubine 12-monooxygenase activity,molecular_function
76537,GO:0047090,Catalysis of the reaction: benzoyl-CoA + H+ + NADPH + O2 = 3-hydroxybenzoyl-CoA + H2O + NADP+.,benzoyl-CoA 3-monooxygenase activity,molecular_function
76538,GO:0047091,Catalysis of the reaction: L-lysine + NADPH + O2 = N(6)-hydroxy-L-lysine + H2O + NADP+.,L-lysine 6-monooxygenase (NADPH) activity,molecular_function
76539,GO:0047093,"Catalysis of the reaction: H+ + NADH + O2 + quinolin-4-ol = H2O + NAD+ + quinoline-3,4-diol.",4-hydroxyquinoline 3-monooxygenase activity,molecular_function
76540,GO:0047094,Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.,3-hydroxyphenylacetate 6-hydroxylase activity,molecular_function
76541,GO:0047095,Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + H2O + NADP+.,2-hydroxycyclohexanone 2-monooxygenase activity,molecular_function
76542,GO:0047096,"Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O2 = A + H2O + testololactone.","androst-4-ene-3,17-dione monooxygenase activity",molecular_function
76543,GO:0047097,"Catalysis of the reaction: AH2 + O2 + phylloquinone = 2,3-epoxyphylloquinone + A + H2O.","phylloquinone monooxygenase (2,3-epoxidizing) activity",molecular_function
76544,GO:0047098,Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.,Latia-luciferin monooxygenase (demethylating) activity,molecular_function
76545,GO:0047099,"Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.",CDP-4-dehydro-6-deoxyglucose reductase activity,molecular_function
76546,GO:0047100,Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.,glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity,molecular_function
76547,GO:0047102,Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.,aminomuconate-semialdehyde dehydrogenase (NAD+) activity,molecular_function
76548,GO:0047104,Catalysis of the reaction: CoA + NAD+ + palmitaldehyde = H+ + NADH + palmitoyl-CoA.,hexadecanal dehydrogenase (acylating) activity,molecular_function
76549,GO:0047105,Catalysis of the reaction: 4-(trimethylamino)butanal + NAD+ + H2O = 4-(trimethylamino)butanoate + NADH + 2 H+.,4-trimethylammoniobutyraldehyde dehydrogenase (NAD+) activity,molecular_function
76550,GO:0047106,Catalysis of the reaction: (4-hydroxyphenyl)acetaldehyde + H2O + NAD+ = 4-hydroxyphenylacetate + 2 H+ + NADH.,4-hydroxyphenylacetaldehyde dehydrogenase (NAD+) activity,molecular_function
76551,GO:0047107,Catalysis of the reaction: 4-guanidinobutanal + H2O + NAD+ = 4-guanidinobutanoate + 2 H+ + NADH.,gamma-guanidinobutyraldehyde dehydrogenase (NAD+) activity,molecular_function
76552,GO:0047108,Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.,(R)-3-hydroxyacid-ester dehydrogenase activity,molecular_function
76553,GO:0047109,Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.,(S)-3-hydroxyacid-ester dehydrogenase activity,molecular_function
76554,GO:0047110,Catalysis of the reaction: CoA + NAD+ + phenylglyoxylate = benzoyl-CoA + CO2 + NADH.,"phenylglyoxylate dehydrogenase (acylating, NAD+) activity",molecular_function
76555,GO:0047111,Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.,formate dehydrogenase (cytochrome-c-553) activity,molecular_function
76556,GO:0047112,Catalysis of the reaction: H+ + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2.,pyruvate oxidase activity,molecular_function
76557,GO:0047113,Catalysis of the reaction: a quinone + an aldehyde + H2O = a carboxylate + a quinol + H+.,aldehyde dehydrogenase (quinone) activity,molecular_function
76558,GO:0047114,"Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.","kynurenate-7,8-dihydrodiol dehydrogenase activity",molecular_function
76559,GO:0047115,"Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.","trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity",molecular_function
76560,GO:0047116,"Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.","1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity",molecular_function
76561,GO:0047118,"Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H+ + NADPH.","2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity",molecular_function
76562,GO:0047120,"Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ = 3,4-dihydroxybenzoate + CO2 + NADH.","(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity",molecular_function
76563,GO:0047121,Catalysis of the reaction: A + H2O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.,isoquinoline 1-oxidoreductase activity,molecular_function
76564,GO:0047122,Catalysis of the reaction: A + H2O + quinaldate = AH(2) + kynurenate.,quinaldate 4-oxidoreductase activity,molecular_function
76565,GO:0047123,"Catalysis of the reaction: A + H2O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2).",quinoline-4-carboxylate 2-oxidoreductase activity,molecular_function
76566,GO:0047124,"Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H2O + NAD+ = (S)-5-amino-3-oxo-hexanoate + H+ + NADH + NH4.","L-erythro-3,5-diaminohexanoate dehydrogenase activity",molecular_function
76567,GO:0047125,Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate.,delta1-piperideine-2-carboxylate reductase activity,molecular_function
76568,GO:0047126,Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H2O + NADP+ = L-ornithine + H+ + NADPH + pyruvate.,N5-(carboxyethyl)ornithine synthase activity,molecular_function
76569,GO:0047127,"Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.",thiomorpholine-carboxylate dehydrogenase activity,molecular_function
76570,GO:0047128,"Catalysis of the reaction: (R)-reticuline + NADP+ = 1,2-dehydroreticuline + H+ + NADPH.","1,2-dehydroreticulinium reductase (NADPH) activity",molecular_function
76571,GO:0047129,Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H2O + NAD+ = L-2-aminopentanoate + H+ + NADH + pyruvate.,opine dehydrogenase activity,molecular_function
76572,GO:0047130,Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH.,"saccharopine dehydrogenase (NADP+, L-lysine-forming) activity",molecular_function
76573,GO:0047131,Catalysis of the reaction: L-saccharopine + H2O + NAD+ = L-glutamate + allysine + H+ + NADH.,"saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity",molecular_function
76574,GO:0047132,Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine.,dihydrobenzophenanthridine oxidase activity,molecular_function
76575,GO:0047133,Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.,dimethylamine dehydrogenase activity,molecular_function
76576,GO:0047134,Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.,protein-disulfide reductase [NAD(P)H] activity,molecular_function
76577,GO:0047135,Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP+ = bis-gamma-glutamylcystine + H+ + NADPH.,bis-gamma-L-glutamylcystine reductase (NADPH) activity,molecular_function
76578,GO:0047136,Catalysis of the reaction: 4-(dimethylamino)azobenzene + H2O + NADP+ = 4-(dimethylamino)phenylazoxybenzene + H+ + NADPH.,4-(dimethylamino)phenylazoxybenzene reductase activity,molecular_function
76579,GO:0047137,Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.,N-hydroxy-2-acetamidofluorene reductase [NAD(P)H] activity,molecular_function
76580,GO:0047139,Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.,glutathione-homocystine transhydrogenase activity,molecular_function
76581,GO:0047140,Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.,glutathione-CoA-glutathione transhydrogenase activity,molecular_function
76582,GO:0047141,Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.,glutathione-cystine transhydrogenase activity,molecular_function
76583,GO:0047142,Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase.,enzyme-thiol transhydrogenase (glutathione-disulfide) activity,molecular_function
76584,GO:0047143,Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H2O + H+.,chlorate reductase activity,molecular_function
76585,GO:0047144,Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.,2-acylglycerol-3-phosphate O-acyltransferase activity,molecular_function
76586,GO:0047145,Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.,demethylsterigmatocystin 6-O-methyltransferase activity,molecular_function
76587,GO:0047146,Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.,sterigmatocystin 7-O-methyltransferase activity,molecular_function
76588,GO:0047147,"Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H+.",trimethylsulfonium-tetrahydrofolate N-methyltransferase activity,molecular_function
76589,GO:0047148,Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH4.,methylamine-glutamate N-methyltransferase activity,molecular_function
76590,GO:0047149,Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H+.,thetin-homocysteine S-methyltransferase activity,molecular_function
76591,GO:0047150,"Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.",betaine-homocysteine S-methyltransferase activity,molecular_function
76592,GO:0047151,"Catalysis of the reaction: uridine54 in tRNA + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(P)H + H+ = 5-methyluridine54 in tRNA + (6S)-5,6,7,8-tetrahydrofolate + NAD(P)+.","tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent",molecular_function
76593,GO:0047152,Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.,methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity,molecular_function
76594,GO:0047153,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.",deoxycytidylate 5-hydroxymethyltransferase activity,molecular_function
76595,GO:0047154,Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.,methylmalonyl-CoA carboxytransferase activity,molecular_function
76596,GO:0047155,Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.,3-hydroxymethylcephem carbamoyltransferase activity,molecular_function
76597,GO:0047156,Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde.,acetoin-ribose-5-phosphate transaldolase activity,molecular_function
76598,GO:0047157,Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.,myelin-proteolipid O-palmitoyltransferase activity,molecular_function
76599,GO:0047158,"Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.",sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity,molecular_function
76600,GO:0047159,Catalysis of the reaction: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA.,plasmalogen synthase activity,molecular_function
76601,GO:0047160,Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.,alkylglycerophosphate 2-O-acetyltransferase activity,molecular_function
76602,GO:0047161,Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.,tartronate O-hydroxycinnamoyltransferase activity,molecular_function
76603,GO:0047162,"Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.",17-O-deacetylvindoline O-acetyltransferase activity,molecular_function
76604,GO:0047163,"Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA.","3,4-dichloroaniline N-malonyltransferase activity",molecular_function
76605,GO:0047164,Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.,isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity,molecular_function
76606,GO:0047165,Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.,flavonol-3-O-beta-glucoside O-malonyltransferase activity,molecular_function
76607,GO:0047166,Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.,1-alkenylglycerophosphoethanolamine O-acyltransferase activity,molecular_function
76608,GO:0047167,Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.,1-alkyl-2-acetylglycerol O-acyltransferase activity,molecular_function
76609,GO:0047168,Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA.,isocitrate O-dihydroxycinnamoyltransferase activity,molecular_function
76610,GO:0047169,Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.,galactarate O-hydroxycinnamoyltransferase activity,molecular_function
76611,GO:0047170,Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.,glucarate O-hydroxycinnamoyltransferase activity,molecular_function
76612,GO:0047171,Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.,glucarolactone O-hydroxycinnamoyltransferase activity,molecular_function
76613,GO:0047172,Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.,shikimate O-hydroxycinnamoyltransferase activity,molecular_function
76614,GO:0047173,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein, but has higher affinity for the bound form.",phosphatidylcholine-retinol O-acyltransferase activity,molecular_function
76615,GO:0047174,Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H+.,putrescine N-hydroxycinnamoyltransferase activity,molecular_function
76616,GO:0047175,Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].,galactosylacylglycerol O-acyltransferase activity,molecular_function
76617,GO:0047176,"Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose.",beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity,molecular_function
76618,GO:0047177,Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine.,glycerophospholipid arachidonoyl-transferase (CoA-independent) activity,molecular_function
76619,GO:0047178,Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.,glycerophospholipid acyltransferase (CoA-dependent) activity,molecular_function
76620,GO:0047179,Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.,platelet-activating factor acetyltransferase activity,molecular_function
76621,GO:0047180,Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.,salutaridinol 7-O-acetyltransferase activity,molecular_function
76622,GO:0047181,"Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.",tetrahydroxybenzophenone synthase activity,molecular_function
76623,GO:0047182,Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.,alcohol O-cinnamoyltransferase activity,molecular_function
76624,GO:0047183,"Catalysis of the reaction: (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside = an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA. Caffeoyl-CoA can also act as an acyl donor.",anthocyanin 5-(6'''-hydroxycinnamoyltransferase) activity,molecular_function
76625,GO:0047184,Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.,1-acylglycerophosphocholine O-acyltransferase activity,molecular_function
76626,GO:0047185,Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.,N-acetylneuraminate 4-O-acetyltransferase activity,molecular_function
76627,GO:0047186,Catalysis of the reaction: CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA.,N-acetylneuraminate 9-O-acetyltransferase activity,molecular_function
76628,GO:0047187,Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate.,deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity,molecular_function
76629,GO:0047188,Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl.,aromatic-hydroxylamine O-acetyltransferase activity,molecular_function
76630,GO:0047189,"Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA.","2,3-diaminopropionate N-oxalyltransferase activity",molecular_function
76631,GO:0047190,"Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.",2-acylglycerophosphocholine O-acyltransferase activity,molecular_function
76632,GO:0047191,Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.,1-alkylglycerophosphocholine O-acyltransferase activity,molecular_function
76633,GO:0047192,Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.,1-alkylglycerophosphocholine O-acetyltransferase activity,molecular_function
76634,GO:0047194,Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.,indoleacetylglucose-inositol O-acyltransferase activity,molecular_function
76635,GO:0047195,"Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol.",diacylglycerol-sterol O-acyltransferase activity,molecular_function
76636,GO:0047196,Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.,long-chain-alcohol O-fatty-acyltransferase activity,molecular_function
76637,GO:0047197,"Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.",triglyceride-sterol O-acyltransferase activity,molecular_function
76638,GO:0047198,Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.,L-cysteine-S-conjugate N-acetyltransferase activity,molecular_function
76639,GO:0047199,"Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol.",phosphatidylcholine-dolichol O-acyltransferase activity,molecular_function
76640,GO:0047200,"Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6-oxopimelate + CoA.",tetrahydrodipicolinate N-acetyltransferase activity,molecular_function
76641,GO:0047201,"Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.",beta-glucogallin O-galloyltransferase activity,molecular_function
76642,GO:0047202,Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.,sinapoylglucose-choline O-sinapoyltransferase activity,molecular_function
76643,GO:0047203,Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.,13-hydroxylupinine O-tigloyltransferase activity,molecular_function
76644,GO:0047204,Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.,chlorogenate-glucarate O-hydroxycinnamoyltransferase activity,molecular_function
76645,GO:0047205,Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.,quinate O-hydroxycinnamoyltransferase activity,molecular_function
76646,GO:0047206,Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala).,UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity,molecular_function
76647,GO:0047207,Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).,"1,2-beta-fructan 1F-fructosyltransferase activity",molecular_function
76648,GO:0047208,"Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H+ + UDP.",o-dihydroxycoumarin 7-O-glucosyltransferase activity,molecular_function
76649,GO:0047209,Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.,coniferyl-alcohol glucosyltransferase activity,molecular_function
76650,GO:0047211,Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.,"alpha-1,4-glucan-protein synthase (ADP-forming) activity",molecular_function
76651,GO:0047212,Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H+ + UDP.,2-coumarate O-beta-glucosyltransferase activity,molecular_function
76652,GO:0047213,Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP.,anthocyanidin 3-O-glucosyltransferase activity,molecular_function
76653,GO:0047214,"Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP.",cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity,molecular_function
76654,GO:0047215,Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.,indole-3-acetate beta-glucosyltransferase activity,molecular_function
76655,GO:0047216,"Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.",inositol 3-alpha-galactosyltransferase activity,molecular_function
76656,GO:0047218,"Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP. Also acts on ferulate, caffeate and sinapate, forming a mixture of 4-glucosides and glucose esters.",hydroxycinnamate 4-beta-glucosyltransferase activity,molecular_function
76657,GO:0047219,Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H+ + UDP.,monoterpenol beta-glucosyltransferase activity,molecular_function
76658,GO:0047220,Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.,galactosylxylosylprotein 3-beta-galactosyltransferase activity,molecular_function
76659,GO:0047221,Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H+ + UDP.,sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity,molecular_function
76660,GO:0047222,"Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.",mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity,molecular_function
76661,GO:0047223,"Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.","beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity",molecular_function
76662,GO:0047224,"Catalysis of the reaction: 3-O-N-acetyl-D-galactosalaminyl-[protein] + UDP-N-acetyl-D-glucosamine = 3-O-N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-[protein] + UDP. Linkage of the glycan to the protein occurs via the oxygen atom in the side chain of an L-serine or L-threonine residue.","acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity",molecular_function
76663,GO:0047225,"Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.","acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity",molecular_function
76664,GO:0047227,Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H+ + UDP.,indolylacetyl-myo-inositol galactosyltransferase activity,molecular_function
76665,GO:0047228,"Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H+ + UDP.","1,2-diacylglycerol 3-glucosyltransferase activity",molecular_function
76666,GO:0047229,Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.,13-hydroxydocosanoate 13-beta-glucosyltransferase activity,molecular_function
76667,GO:0047230,Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.,flavonol-3-O-glucoside L-rhamnosyltransferase activity,molecular_function
76668,GO:0047231,Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H+ + UDP.,pyridoxine 5'-O-beta-D-glucosyltransferase activity,molecular_function
76669,GO:0047233,Catalysis of the reaction: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminyl-(2->3)]-beta-D-galactosyl derivative + UDP + H+.,"N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity",molecular_function
76670,GO:0047234,Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.,raffinose-raffinose alpha-galactotransferase activity,molecular_function
76671,GO:0047235,Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.,sucrose 6F-alpha-galactotransferase activity,molecular_function
76672,GO:0047236,Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.,methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity,molecular_function
76673,GO:0047237,"Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.",glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,molecular_function
76674,GO:0047238,"Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.",glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,molecular_function
76675,GO:0047239,Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H+ + taxiphyllin + UDP.,hydroxymandelonitrile glucosyltransferase activity,molecular_function
76676,GO:0047240,Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H+ + UDP.,"lactosylceramide beta-1,3-galactosyltransferase activity",molecular_function
76677,GO:0047241,"Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.",lipopolysaccharide N-acetylmannosaminouronosyltransferase activity,molecular_function
76678,GO:0047242,Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.,hydroxyanthraquinone glucosyltransferase activity,molecular_function
76679,GO:0047243,Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.,flavanone 7-O-beta-glucosyltransferase activity,molecular_function
76680,GO:0047244,"Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.",N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity,molecular_function
76681,GO:0047245,"Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.",N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity,molecular_function
76682,GO:0047246,Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.,luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity,molecular_function
76683,GO:0047247,Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.,luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity,molecular_function
76684,GO:0047248,Catalysis of the reaction: nuatigenin + UDP-D-glucose = H+ + nuatigenin 3-beta-D-glucopyranoside + UDP.,nuatigenin 3-beta-glucosyltransferase activity,molecular_function
76685,GO:0047249,Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H+ + UDP.,sarsapogenin 3-beta-glucosyltransferase activity,molecular_function
76686,GO:0047250,Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H+ + UDP.,4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity,molecular_function
76687,GO:0047251,Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.,thiohydroximate beta-D-glucosyltransferase activity,molecular_function
76688,GO:0047252,Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.,beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity,molecular_function
76689,GO:0047253,"Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.","alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",molecular_function
76690,GO:0047254,"Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.","2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity",molecular_function
76691,GO:0047255,"Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.",galactogen 6-beta-galactosyltransferase activity,molecular_function
76692,GO:0047256,Catalysis of the reaction: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H+ + UDP.,"lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity",molecular_function
76693,GO:0047257,"Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.",diglucosyl diacylglycerol synthase activity,molecular_function
76694,GO:0047258,Catalysis of the reaction: sphingosine + UDP-D-galactose = H+ + psychosine + UDP.,sphingosine beta-galactosyltransferase activity,molecular_function
76695,GO:0047259,Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.,glucomannan 4-beta-mannosyltransferase activity,molecular_function
76696,GO:0047260,"Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.","alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity",molecular_function
76697,GO:0047261,Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H+ + UDP.,steroid N-acetylglucosaminyltransferase activity,molecular_function
76698,GO:0047262,"Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.",polygalacturonate 4-alpha-galacturonosyltransferase activity,molecular_function
76699,GO:0047264,"Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP. 1,2- and 1,3-mannosyl bonds are formed.",heteroglycan alpha-mannosyltransferase activity,molecular_function
76700,GO:0047265,Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.,poly(glycerol-phosphate) alpha-glucosyltransferase activity,molecular_function
76701,GO:0047266,Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.,poly(ribitol-phosphate) beta-glucosyltransferase activity,molecular_function
76702,GO:0047267,Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.,undecaprenyl-phosphate mannosyltransferase activity,molecular_function
76703,GO:0047268,Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.,galactinol-raffinose galactosyltransferase activity,molecular_function
76704,GO:0047269,Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.,poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity,molecular_function
76705,GO:0047270,Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + alpha-D-glucosyl-lipopolysaccharide.,lipopolysaccharide glucosyltransferase II activity,molecular_function
76706,GO:0047271,Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.,glycosaminoglycan galactosyltransferase activity,molecular_function
76707,GO:0047272,Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.,phosphopolyprenol glucosyltransferase activity,molecular_function
76708,GO:0047273,Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.,galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity,molecular_function
76709,GO:0047274,Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.,galactinol-sucrose galactosyltransferase activity,molecular_function
76710,GO:0047276,"Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.",N-acetyllactosaminide 3-alpha-galactosyltransferase activity,molecular_function
76711,GO:0047277,"Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.",globoside alpha-N-acetylgalactosaminyltransferase activity,molecular_function
76712,GO:0047278,Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.,bilirubin-glucuronoside glucuronosyltransferase activity,molecular_function
76713,GO:0047279,Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H+ + UDP.,sn-glycerol-3-phosphate 1-galactosyltransferase activity,molecular_function
76714,GO:0047280,Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H+ + nicotinamide.,nicotinamide phosphoribosyltransferase activity,molecular_function
76715,GO:0047281,"Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.",dioxotetrahydropyrimidine phosphoribosyltransferase activity,molecular_function
76716,GO:0047282,Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H+.,dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity,molecular_function
76717,GO:0047283,Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.,dolichyl-phosphate D-xylosyltransferase activity,molecular_function
76718,GO:0047284,Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.,dolichyl-xylosyl-phosphate-protein xylosyltransferase activity,molecular_function
76719,GO:0047285,Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.,flavonol-3-O-glycoside xylosyltransferase activity,molecular_function
76720,GO:0047286,Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.,NAD+-diphthamide ADP-ribosyltransferase activity,molecular_function
76721,GO:0047288,Catalysis of the reaction: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H+.,"beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase activity",molecular_function
76722,GO:0047289,"Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H+.","galactosyldiacylglycerol alpha-2,3-sialyltransferase activity",molecular_function
76723,GO:0047290,Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.,"alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",molecular_function
76724,GO:0047291,"Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.","lactosylceramide alpha-2,3-sialyltransferase activity",molecular_function
76725,GO:0047292,"Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.",trihydroxypterocarpan dimethylallyltransferase activity,molecular_function
76726,GO:0047294,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate.",phosphoglycerol geranylgeranyltransferase activity,molecular_function
76727,GO:0047295,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate.",geranylgeranylglycerol-phosphate geranylgeranyltransferase activity,molecular_function
76728,GO:0047296,Catalysis of the reaction: 2 putrescine = sym-homospermidine + NH4+.,homospermidine synthase activity,molecular_function
76729,GO:0047297,Catalysis of the reaction: L-asparagine + a 2-oxocarboxylate = 2-oxosuccinamate + an L-alpha-amino acid.,L-asparagine:oxo-acid transaminase activity,molecular_function
76730,GO:0047298,Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.,(S)-3-amino-2-methylpropionate:2-oxoglutarate transaminase activity,molecular_function
76731,GO:0047299,Catalysis of the reaction: 3-phenylpyruvate + L-tryptophan = indole-3-pyruvate + L-phenylalanine.,L-tryptophan:phenylpyruvate transaminase activity,molecular_function
76732,GO:0047300,Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.,pyridoxamine:pyruvate transaminase activity,molecular_function
76733,GO:0047301,Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.,L-valine:3-methyl-2-oxovalerate transaminase activity,molecular_function
76734,GO:0047302,"Catalysis of the reaction: UDP-N-acetylbacillosamine + 2-oxoglutarate = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + L-glutamate.",UDP-N-acetylbacillosamine:2-oxoglutarate transaminase activity,molecular_function
76735,GO:0047303,Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.,glycine:oxaloacetate transaminase activity,molecular_function
76736,GO:0047304,Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.,2-aminoethylphosphonate:pyruvate transaminase activity,molecular_function
76737,GO:0047305,Catalysis of the reaction: (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.,(R)-3-amino-2-methylpropionate:pyruvate transaminase activity,molecular_function
76738,GO:0047306,Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.,D-methionine:pyruvate transaminase activity,molecular_function
76739,GO:0047307,"Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.","L-2,4-diaminobutyrate:pyruvate transaminase activity",molecular_function
76740,GO:0047308,Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.,L-alanine:oxomalonate transaminase activity,molecular_function
76741,GO:0047309,"Catalysis of the reaction: L-dopa + 2-oxoglutarate = 3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate.",dihydroxyphenylalanine:2-oxoglutarate transaminase activity,molecular_function
76742,GO:0047310,Catalysis of the reaction: scyllo-inosose + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.,L-glutamine:scyllo-inositol transaminase activity,molecular_function
76743,GO:0047311,"Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.","1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate transaminase activity",molecular_function
76744,GO:0047312,Catalysis of the reaction: L-phenylalanine + pyruvate = 3-phenylpyruvate + L-alanine.,L-phenylalanine:pyruvate transaminase activity,molecular_function
76745,GO:0047313,Catalysis of the reaction: an aromatic L-alpha-amino acid + glyoxylate = an aromatic oxo-acid + glycine.,aromatic-amino-acid:glyoxylate transaminase activity,molecular_function
76746,GO:0047315,"Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.",L-kynurenine:glyoxylate transaminase activity,molecular_function
76747,GO:0047316,Catalysis of the reaction: 3-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.,L-glutamine:phenylpyruvate transaminase activity,molecular_function
76748,GO:0047317,Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.,N6-acetyl-beta-lysine:2-oxoglutarate transaminase activity,molecular_function
76749,GO:0047319,Catalysis of the reaction: L-aspartate + 3-phenylpyruvate = oxaloacetate + L-phenylalanine.,L-aspartate:phenylpyruvate transaminase activity,molecular_function
76750,GO:0047320,Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.,D-4-hydroxyphenylglycine:2-oxoglutarate transaminase activity,molecular_function
76751,GO:0047321,Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.,diphosphate-protein phosphotransferase activity,molecular_function
76752,GO:0047322,Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.,[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity,molecular_function
76753,GO:0047323,Catalysis of the reaction: ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H+ + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].,[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity,molecular_function
76754,GO:0047324,Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.,phosphoenolpyruvate-glycerone phosphotransferase activity,molecular_function
76755,GO:0047325,"Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.","inositol-3,4,5,6-tetrakisphosphate 1-kinase activity",molecular_function
76756,GO:0047326,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.","inositol-1,3,4,6-tetrakisphosphate 5-kinase activity",molecular_function
76757,GO:0047327,Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.,glycerol-3-phosphate-glucose phosphotransferase activity,molecular_function
76758,GO:0047328,Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.,acyl-phosphate-hexose phosphotransferase activity,molecular_function
76759,GO:0047329,Catalysis of the reaction: phosphoramidate + a D-hexose + H+ = alpha-D-hexose 1-phosphate + NH4+.,phosphoramidate-hexose phosphotransferase activity,molecular_function
76760,GO:0047330,Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.,polyphosphate-glucose phosphotransferase activity,molecular_function
76761,GO:0047331,Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H+ + phosphate.,diphosphate-glycerol phosphotransferase activity,molecular_function
76762,GO:0047332,Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H+ + phosphate.,diphosphate-serine phosphotransferase activity,molecular_function
76763,GO:0047333,"Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H+.",dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity,molecular_function
76764,GO:0047334,"Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.",diphosphate-fructose-6-phosphate 1-phosphotransferase activity,molecular_function
76765,GO:0047335,Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.,3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity,molecular_function
76766,GO:0047336,Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H+.,5-methyldeoxycytidine-5'-phosphate kinase activity,molecular_function
76767,GO:0047337,Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.,dolichyl-diphosphate-polyphosphate phosphotransferase activity,molecular_function
76768,GO:0047338,Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.,UTP:xylose-1-phosphate uridylyltransferase activity,molecular_function
76769,GO:0047339,Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.,nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity,molecular_function
76770,GO:0047341,Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP + H+ = diphosphate + GDP-beta-L-fucose.,fucose-1-phosphate guanylyltransferase activity,molecular_function
76771,GO:0047342,Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.,galactose-1-phosphate thymidylyltransferase activity,molecular_function
76772,GO:0047343,Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.,glucose-1-phosphate cytidylyltransferase activity,molecular_function
76773,GO:0047344,Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.,glucose-1-phosphate guanylyltransferase activity,molecular_function
76774,GO:0047345,Catalysis of the reaction: D-ribose 5-phosphate + ADP + H+ = ADP-ribose + phosphate.,ribose-5-phosphate adenylyltransferase activity,molecular_function
76775,GO:0047346,Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.,aldose-1-phosphate adenylyltransferase activity,molecular_function
76776,GO:0047347,Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.,aldose-1-phosphate nucleotidyltransferase activity,molecular_function
76777,GO:0047348,Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.,glycerol-3-phosphate cytidylyltransferase activity,molecular_function
76778,GO:0047349,Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.,D-ribitol-5-phosphate cytidylyltransferase activity,molecular_function
76779,GO:0047350,Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.,glucuronate-1-phosphate uridylyltransferase activity,molecular_function
76780,GO:0047351,"Catalysis of the reaction: 2 GTP + H+ = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H+.",GTP guanylyltransferase activity,molecular_function
76781,GO:0047352,Catalysis of the reaction: 5'-adenylyl sulfate + NH4 = adenosine 5'-phosphoramidate + 2 H+ + sulfate.,adenylylsulfate-ammonia adenylyltransferase activity,molecular_function
76782,GO:0047353,Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.,N-methylphosphoethanolamine cytidylyltransferase activity,molecular_function
76783,GO:0047354,Catalysis of the reaction: CDP-choline + sphingosine = CMP + H+ + sphingosyl-phosphocholine.,sphingosine cholinephosphotransferase activity,molecular_function
76784,GO:0047355,Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.,CDP-glycerol glycerophosphotransferase activity,molecular_function
76785,GO:0047356,Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.,CDP-ribitol ribitolphosphotransferase activity,molecular_function
76786,GO:0047357,Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H+ + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.,UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity,molecular_function
76787,GO:0047358,Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.,UDP-glucose-glycoprotein glucose phosphotransferase activity,molecular_function
76788,GO:0047359,Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.,1-alkenyl-2-acylglycerol choline phosphotransferase activity,molecular_function
76789,GO:0047360,Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.,undecaprenyl-phosphate galactose phosphotransferase activity,molecular_function
76790,GO:0047361,Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.,phosphomannan mannosephosphotransferase activity,molecular_function
76791,GO:0047362,Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.,thiosulfate-dithiol sulfurtransferase activity,molecular_function
76792,GO:0047363,"Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.",triglucosylalkylacylglycerol sulfotransferase activity,molecular_function
76793,GO:0047364,"Catalysis of the reaction: (Z)-desulfoglucotropeolin + 3'-phosphoadenylyl sulfate = (Z)-glucotropeolin + adenosine 3',5'-bisphosphate + H+. Also converts (Z)-indolylmethyl desulfoglucosinolate to (Z)-glucobrassicin. This is the final step in the biosynthesis of the glucosinolate core structure.",aromatic desulfoglucosinolate sulfotransferase activity,molecular_function
76794,GO:0047365,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,3'-disulfate.",quercetin-3-sulfate 3'-sulfotransferase activity,molecular_function
76795,GO:0047366,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,4'-disulfate.",quercetin-3-sulfate 4'-sulfotransferase activity,molecular_function
76796,GO:0047367,"Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.","quercetin-3,3'-bissulfate 7-sulfotransferase activity",molecular_function
76797,GO:0047368,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H+ + UDP-N-acetyl-D-galactosamine 4,6-disulfate.",UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity,molecular_function
76798,GO:0047369,Catalysis of the reaction: 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate.,succinate-hydroxymethylglutarate CoA-transferase activity,molecular_function
76799,GO:0047370,Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.,succinate-citramalate CoA-transferase activity,molecular_function
76800,GO:0047371,Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.,butyrate-acetoacetate CoA-transferase activity,molecular_function
76801,GO:0047372,Catalysis of the reaction: a monoacylglycerol + H2O = a fatty acid + glycerol + H+.,monoacylglycerol lipase activity,molecular_function
76802,GO:0047373,"Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H+.",acetoxybutynylbithiophene deacetylase activity,molecular_function
76803,GO:0047374,Catalysis of the reaction: 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H+.,methylumbelliferyl-acetate deacetylase activity,molecular_function
76804,GO:0047375,Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.,N-acetylgalactosaminoglycan deacetylase activity,molecular_function
76805,GO:0047376,Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.,"all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity",molecular_function
76806,GO:0047377,"Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H+.","5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity",molecular_function
76807,GO:0047378,Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H2O = 1-alkyl-sn-glycerol + acetate + H+.,acetylalkylglycerol acetylhydrolase activity,molecular_function
76808,GO:0047382,Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H2O = S-methyl-1-thio-D-glycerate + phosphate.,methylphosphothioglycerate phosphatase activity,molecular_function
76809,GO:0047383,Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.,guanidinodeoxy-scyllo-inositol-4-phosphatase activity,molecular_function
76810,GO:0047384,Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].,[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity,molecular_function
76811,GO:0047385,Catalysis of the reaction: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.,[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity,molecular_function
76812,GO:0047386,"Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructofuranose 2-phosphate + phosphate.","fructose-2,6-bisphosphate 6-phosphatase activity",molecular_function
76813,GO:0047387,Catalysis of the reaction: H2O + serine phosphoethanolamine = H+ + phosphoethanolamine + serine.,serine-ethanolaminephosphate phosphodiesterase activity,molecular_function
76814,GO:0047388,Catalysis of the reaction: [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP.,[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity,molecular_function
76815,GO:0047389,Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.,glycerophosphocholine phosphodiesterase activity,molecular_function
76816,GO:0047390,Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.,glycerophosphocholine cholinephosphodiesterase activity,molecular_function
76817,GO:0047391,Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.,alkylglycerophosphoethanolamine phosphodiesterase activity,molecular_function
76818,GO:0047392,Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.,CMP-N-acylneuraminate phosphodiesterase activity,molecular_function
76819,GO:0047393,"Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H2O = glycerol 1-phosphate + H+.","glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity",molecular_function
76820,GO:0047394,Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.,glycerophosphoinositol inositolphosphodiesterase activity,molecular_function
76821,GO:0047395,Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.,glycerophosphoinositol glycerophosphodiesterase activity,molecular_function
76822,GO:0047396,"Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.",glycosylphosphatidylinositol diacylglycerol-lyase activity,molecular_function
76823,GO:0047397,Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.,dolichylphosphate-glucose phosphodiesterase activity,molecular_function
76824,GO:0047398,Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.,dolichylphosphate-mannose phosphodiesterase activity,molecular_function
76825,GO:0047399,Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.,glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity,molecular_function
76826,GO:0047400,Catalysis of the reaction: H2O + phosphonoacetate = acetate + H+ + phosphate.,phosphonoacetate hydrolase activity,molecular_function
76827,GO:0047401,Catalysis of the reaction: H2O + trithionate = H+ + sulfate + thiosulfate.,trithionate hydrolase activity,molecular_function
76828,GO:0047402,"Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.",protein-glucosylgalactosylhydroxylysine glucosidase activity,molecular_function
76829,GO:0047403,"Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.",lacto-N-biosidase activity,molecular_function
76830,GO:0047404,"Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.",glucuronosyl-disulfoglucosamine glucuronidase activity,molecular_function
76831,GO:0047405,Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.,pyrimidine-5'-nucleotide nucleosidase activity,molecular_function
76832,GO:0047406,Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-D-glucosamine + L-asparagine.,beta-aspartyl-N-acetylglucosaminidase activity,molecular_function
76833,GO:0047408,Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.,alkenylglycerophosphocholine hydrolase activity,molecular_function
76834,GO:0047411,Catalysis of the reaction: 2-(acetamidomethylene)succinate + 2 H2O + H+ = succinate semialdehyde + acetate + NH4+ + CO2.,2-(acetamidomethylene)succinate hydrolase activity,molecular_function
76835,GO:0047412,Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.,N-(long-chain-acyl)ethanolamine deacylase activity,molecular_function
76836,GO:0047413,Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H2O + H+ = L-leucine + benzyl alcohol + CO2.,N(alpha)-benzyloxycarbonylleucine hydrolase activity,molecular_function
76837,GO:0047414,Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H2O + H+ = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4.,2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity,molecular_function
76838,GO:0047415,Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H+.,D-benzoylarginine-4-nitroanilide amidase activity,molecular_function
76839,GO:0047416,Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.,arylalkyl acylamidase activity,molecular_function
76840,GO:0047417,Catalysis of the reaction: an N-carbamoyl-D-amino acid + H2O + 2 H+ = a D-alpha-amino acid + NH4+ + CO2.,N-carbamoyl-D-amino acid hydrolase activity,molecular_function
76841,GO:0047418,Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.,phthalyl amidase activity,molecular_function
76842,GO:0047419,Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.,N-acetylgalactosamine-6-phosphate deacetylase activity,molecular_function
76843,GO:0047420,Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.,N-acyl-D-amino-acid deacylase activity,molecular_function
76844,GO:0047421,Catalysis of the reaction: N-acyl-D-glutamate + H2O = D-glutamate + a carboxylate.,N-acyl-D-glutamate deacylase activity,molecular_function
76845,GO:0047422,Catalysis of the reaction: N-acyl-D-aspartate + H2O = D-aspartate + a carboxylate.,N-acyl-D-aspartate deacylase activity,molecular_function
76846,GO:0047423,Catalysis of the reaction: N-methylhydantoin + ATP + 2 H2O = N-carbamoylsarcosine + ADP + 3 H+ + phosphate.,N-methylhydantoinase (ATP-hydrolyzing) activity,molecular_function
76847,GO:0047424,Catalysis of the reaction: methylenediurea + 2 H2O + 2 H+ = N-(hydroxymethyl)urea + 2 NH4+ + CO2.,methylenediurea deaminase activity,molecular_function
76848,GO:0047425,"Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H2O + H+ = 2,5-dioxopentanoate + NH4.",1-pyrroline-4-hydroxy-2-carboxylate deaminase activity,molecular_function
76849,GO:0047426,"Catalysis of the reaction: ricinine + 2 H2O = 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4+.",ricinine nitrilase activity,molecular_function
76850,GO:0047427,Catalysis of the reaction: 3-cyano-L-alanine + 2 H2O + H+ = L-aspartate + NH4.,cyanoalanine nitrilase activity,molecular_function
76851,GO:0047428,Catalysis of the reaction: 4-chlorophenylacetonitrile + 2 H2O = 4-chlorophenylacetate + NH4+.,arylacetonitrilase activity,molecular_function
76852,GO:0047429,Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.,nucleoside triphosphate diphosphatase activity,molecular_function
76853,GO:0047430,Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.,oligosaccharide-diphosphodolichol diphosphatase activity,molecular_function
76854,GO:0047431,"Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H+ = 5-hydroxy-6-methylpyridine-3-carboxylate + CO2.","3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity",molecular_function
76855,GO:0047432,"Catalysis of the reaction: 2,2-dialkylglycine + H+ + pyruvate = L-alanine + CO2 + dialkyl ketone.","2,2-dialkylglycine decarboxylase (pyruvate) activity",molecular_function
76856,GO:0047433,Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H+ = 2-methylbutanal + CO2.,branched-chain-2-oxoacid decarboxylase activity,molecular_function
76857,GO:0047434,Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.,indolepyruvate decarboxylase activity,molecular_function
76858,GO:0047435,Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H+ = 4-guanidinobutanal + CO2.,5-guanidino-2-oxopentanoate decarboxylase activity,molecular_function
76859,GO:0047436,Catalysis of the reaction: 2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2.,arylmalonate decarboxylase activity,molecular_function
76860,GO:0047437,Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.,4-oxalocrotonate decarboxylase activity,molecular_function
76861,GO:0047438,Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.,2-dehydro-3-deoxy-L-pentonate aldolase activity,molecular_function
76862,GO:0047439,Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.,3-deoxy-D-manno-octulosonate aldolase activity,molecular_function
76863,GO:0047440,Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.,2-dehydro-3-deoxy-D-pentonate aldolase activity,molecular_function
76864,GO:0047441,Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.,5-dehydro-2-deoxyphosphogluconate aldolase activity,molecular_function
76865,GO:0047443,"Catalysis of the reactions: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate, and 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = oxaloacetate + pyruvate.",4-hydroxy-4-methyl-2-oxoglutarate aldolase activity,molecular_function
76866,GO:0047444,Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.,N-acylneuraminate-9-phosphate synthase activity,molecular_function
76867,GO:0047445,Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H+ = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.,3-hydroxy-3-isohexenylglutaryl-CoA lyase activity,molecular_function
76868,GO:0047446,Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.,(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity,molecular_function
76869,GO:0047447,Catalysis of the reaction: 3-hydroxy-L-aspartate = oxaloacetate + NH4+.,erythro-3-hydroxyaspartate ammonia-lyase activity,molecular_function
76870,GO:0047448,"Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.",5-dehydro-4-deoxyglucarate dehydratase activity,molecular_function
76871,GO:0047449,"Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O.",2-dehydro-3-deoxy-L-arabinonate dehydratase activity,molecular_function
76872,GO:0047452,Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin.,protoaphin-aglucone dehydratase (cyclizing) activity,molecular_function
76873,GO:0047453,"Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + H+ + NAD(P)H + phosphate.",ATP-dependent NAD(P)H-hydrate dehydratase activity,molecular_function
76874,GO:0047454,Catalysis of the reaction: phaseollidin hydrate = H2O + phaseollidin.,phaseollidin hydratase activity,molecular_function
76875,GO:0047455,Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.,16-alpha-hydroxyprogesterone dehydratase activity,molecular_function
76876,GO:0047456,"Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H2O.",2-methylisocitrate dehydratase activity,molecular_function
76877,GO:0047457,"Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.","exo-(1,4)-alpha-D-glucan lyase activity",molecular_function
76878,GO:0047458,Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H+.,beta-pyrazolylalanine synthase activity,molecular_function
76879,GO:0047459,Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH4.,3-aminobutyryl-CoA ammonia-lyase activity,molecular_function
76880,GO:0047460,Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H2O = 2-oxopent-4-enoate + chloride + H+ + NH4.,L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity,molecular_function
76881,GO:0047461,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.",(+)-delta-cadinene synthase activity,molecular_function
76882,GO:0047462,Catalysis of the reaction: L-phenylalanine + ATP + H2O = D-phenylalanine + AMP + diphosphate + 2 H+.,phenylalanine racemase (ATP-hydrolyzing) activity,molecular_function
76883,GO:0047463,Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.,2-aminohexano-6-lactam racemase activity,molecular_function
76884,GO:0047464,Catalysis of the reaction: (heparosan-N-sulfate)(n) = (heparan-N-sulfate)(n). Converts D-glucosyluronate residues to L-iduronate residues.,heparosan-N-sulfate-glucuronate 5-epimerase activity,molecular_function
76885,GO:0047465,Catalysis of the reaction: an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate.,N-acylglucosamine-6-phosphate 2-epimerase activity,molecular_function
76886,GO:0047466,"Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.","2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity",molecular_function
76887,GO:0047469,"Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.",4-carboxymethyl-4-methylbutenolide mutase activity,molecular_function
76888,GO:0047470,Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.,"(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity",molecular_function
76889,GO:0047471,Catalysis of the reaction: maltose = trehalose.,maltose alpha-D-glucosyltransferase activity,molecular_function
76890,GO:0047472,"Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H+.","3-carboxy-cis,cis-muconate cycloisomerase activity",molecular_function
76891,GO:0047473,"Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: holo-[D-alanyl-carrier protein] + D-alanine + ATP = D-alanyl-[D-alanyl-carrier protein] + AMP + diphosphate.",D-alanine [D-alanyl carrier protein] ligase activity,molecular_function
76892,GO:0047474,Catalysis of the reaction: a long-chain fatty acid + ATP + L-cysteinyl-[protein] = AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid--protein ligase activity,molecular_function
76893,GO:0047475,Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H+ + phenylacetyl-CoA.,phenylacetate-CoA ligase activity,molecular_function
76894,GO:0047476,"Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.","3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity",molecular_function
76895,GO:0047478,Catalysis of the reaction: L-aspartate + ATP + NH4 = L-asparagine + ADP + 2 H+ + phosphate.,aspartate-ammonia ligase (ADP-forming) activity,molecular_function
76896,GO:0047479,Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.,trypanothione synthase activity,molecular_function
76897,GO:0047480,Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.,UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity,molecular_function
76898,GO:0047481,Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.,D-alanine-alanyl-poly(glycerolphosphate) ligase activity,molecular_function
76899,GO:0047482,Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.,UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity,molecular_function
76900,GO:0047483,Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H+ + phosphate.,imidazoleacetate-phosphoribosyldiphosphate ligase activity,molecular_function
76901,GO:0047484,Any process that modulates the rate or extent of the response to osmotic stress.,regulation of response to osmotic stress,biological_process
76902,GO:0047487,Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.,oligogalacturonide lyase activity,molecular_function
76903,GO:0047488,"Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.",heparin lyase activity,molecular_function
76904,GO:0047489,"Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.",pectate disaccharide-lyase activity,molecular_function
76905,GO:0047490,Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.,pectin lyase activity,molecular_function
76906,GO:0047491,"Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.",poly(alpha-L-guluronate) lyase activity,molecular_function
76907,GO:0047492,"Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.",xanthan lyase activity,molecular_function
76908,GO:0047493,Catalysis of the reaction: CDP-choline + ceramide = CMP + H+ + sphingomyelin.,ceramide cholinephosphotransferase activity,molecular_function
76909,GO:0047494,Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H+.,serine-phosphoethanolamine synthase activity,molecular_function
76910,GO:0047495,Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.,membrane-oligosaccharide glycerophosphotransferase activity,molecular_function
76911,GO:0047496,"The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.",vesicle transport along microtubule,biological_process
76912,GO:0047497,"The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.",mitochondrion transport along microtubule,biological_process
76913,GO:0047500,"Catalysis of the reaction: (+)-borneol + NAD+ = (1R, 4R)-camphor + H+ + NADH.",(+)-borneol dehydrogenase activity,molecular_function
76914,GO:0047501,"Catalysis of the reaction: (+)-neomenthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.",(+)-neomenthol dehydrogenase activity,molecular_function
76915,GO:0047502,"Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (1S,5S)-sabinone + H+ + NADH.",(+)-sabinol dehydrogenase activity,molecular_function
76916,GO:0047503,"Catalysis of the reaction: (-)-borneol + NAD+ = (1S,4S)-camphor + H+ + NADH.",(-)-borneol dehydrogenase activity,molecular_function
76917,GO:0047504,"Catalysis of the reaction: (-)-menthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.",(-)-menthol dehydrogenase activity,molecular_function
76918,GO:0047505,"Catalysis of the reaction: (-)-menthol + H+ + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP+.",(-)-menthol monooxygenase activity,molecular_function
76919,GO:0047506,Catalysis of the reaction: dAMP + ATP = dADP + ADP.,dAMP kinase activity,molecular_function
76920,GO:0047507,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + ATP = a 2'-deoxyribonucleoside 5'-diphosphate + ADP.,"deoxynucleoside phosphate kinase activity, ATP as phosphate donor",molecular_function
76921,GO:0047508,Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H2O.,(R)-2-methylmalate dehydratase activity,molecular_function
76922,GO:0047509,"Catalysis of the reaction: (R)-4-dehydropantoate + NAD+ + H2O = (R)-3,3-dimethylmalate + NADH + 2 H+.",(R)-dehydropantoate dehydrogenase activity,molecular_function
76923,GO:0047510,Catalysis of the reaction: S-citramalate = H2O + mesaconate.,(S)-2-methylmalate dehydratase activity,molecular_function
76924,GO:0047511,Catalysis of the reaction: (S)-methylmalonyl-CoA + H2O = CoA + H+ + methylmalonate.,(S)-methylmalonyl-CoA hydrolase activity,molecular_function
76925,GO:0047512,"Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD+ = acetoin + H+ + NADH.","(S,S)-butanediol dehydrogenase activity",molecular_function
76926,GO:0047513,Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.,"1,2-alpha-L-fucosidase activity",molecular_function
76927,GO:0047514,Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.,"1,3-beta-D-glucan phosphorylase activity",molecular_function
76928,GO:0047515,Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.,"1,3-beta-oligoglucan phosphorylase activity",molecular_function
76929,GO:0047516,"Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.","1,3-propanediol dehydrogenase activity",molecular_function
76930,GO:0047517,Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).,"1,4-beta-D-xylan synthase activity",molecular_function
76931,GO:0047518,Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + ribofuranose.,1-methyladenosine nucleosidase activity,molecular_function
76932,GO:0047519,Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.,quinate dehydrogenase (quinone) activity,molecular_function
76933,GO:0047520,Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + H+ + palmitate.,11-cis-retinyl-palmitate hydrolase activity,molecular_function
76934,GO:0047521,"Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + H+ + NADPH.",12-beta-hydroxysteroid dehydrogenase (NADP+) activity,molecular_function
76935,GO:0047522,"Catalysis of the reaction: 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(P)+ = 15-oxoprostaglandin E2 + H+ + NAD(P)H.",15-oxoprostaglandin 13-reductase [NAD(P)+] activity,molecular_function
76936,GO:0047524,Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.,16-hydroxysteroid epimerase activity,molecular_function
76937,GO:0047525,Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.,2'-hydroxydaidzein reductase activity,molecular_function
76938,GO:0047526,Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.,2'-hydroxyisoflavone reductase activity,molecular_function
76939,GO:0047527,"Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.","2,3-dihydroxybenzoate-serine ligase activity",molecular_function
76940,GO:0047528,"Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2 + H+.","2,3-dihydroxyindole 2,3-dioxygenase activity",molecular_function
76941,GO:0047529,"Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.","2,3-dimethylmalate lyase activity",molecular_function
76942,GO:0047530,"Catalysis of the reaction: (2R,4S)-2,4-diaminopentanoate + NADP+ + H2O = (2R)-2-amino-4-oxopentanoate + NH4+ + NADPH + H+.","2,4-diaminopentanoate dehydrogenase activity",molecular_function
76943,GO:0047532,"Catalysis of the reaction: 2,5-dioxopiperazine + H2O = glycylglycine.","2,5-dioxopiperazine hydrolase activity",molecular_function
76944,GO:0047533,"Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.","2,5-dioxovalerate dehydrogenase (NADP+) activity",molecular_function
76945,GO:0047534,Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.,2-acetolactate mutase activity,molecular_function
76946,GO:0047535,"Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.",2-alkyn-1-ol dehydrogenase activity,molecular_function
76947,GO:0047536,Catalysis of the reaction: L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.,L-2-aminoadipate:2-oxoglutarate transaminase activity,molecular_function
76948,GO:0047537,Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.,L-2-aminohexanoate:2-oxoglutarate transaminase activity,molecular_function
76949,GO:0047538,Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate.,2-carboxy-D-arabinitol-1-phosphatase activity,molecular_function
76950,GO:0047539,Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.,2-deoxyglucosidase activity,molecular_function
76951,GO:0047540,Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.,2-enoate reductase activity,molecular_function
76952,GO:0047541,Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H+.,2-furoate-CoA ligase activity,molecular_function
76953,GO:0047542,Catalysis of the reaction: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH(2) + H+.,2-furoyl-CoA dehydrogenase activity,molecular_function
76954,GO:0047543,Catalysis of the reaction: NADP+ + palmitaldehyde = trans-hexadec-2-enal + H+ + NADPH.,2-hexadecenal reductase activity,molecular_function
76955,GO:0047544,"Catalysis of the reaction: biphenyl-2-ol + H+ + NADH + O2 = biphenyl-2,3-diol + H2O + NAD+. Also converts 2,2'-dihydroxybiphenyl into 2,2',3-trihydroxy-biphenyl.",2-hydroxybiphenyl 3-monooxygenase (NADH) activity,molecular_function
76956,GO:0047545,Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.,(S)-2-hydroxyglutarate dehydrogenase activity,molecular_function
76957,GO:0047546,"Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O2 = 2,5-dihydroxypyridine + A + H2O.",2-hydroxypyridine 5-monooxygenase activity,molecular_function
76958,GO:0047547,"Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H2O.",2-methylcitrate dehydratase activity,molecular_function
76959,GO:0047548,Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.,2-methyleneglutarate mutase activity,molecular_function
76960,GO:0047549,Catalysis of the reaction: 2-nitrophenol + 2 H+ + 2 NADPH + O2 = catechol + H2O + 2 NADP+ + nitrite.,2-nitrophenol 2-monooxygenase activity,molecular_function
76961,GO:0047550,Catalysis of the reaction: 2-hydroxyadipate + NAD+ = 2-oxoadipate + H+ + NADH.,2-oxoadipate reductase activity,molecular_function
76962,GO:0047551,Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.,2-oxoaldehyde dehydrogenase (NAD+) activity,molecular_function
76963,GO:0047552,Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.,2-oxoaldehyde dehydrogenase (NADP+) activity,molecular_function
76964,GO:0047553,Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.,2-oxoglutarate synthase activity,molecular_function
76965,GO:0047554,"Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H2O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H+.","2-pyrone-4,6-dicarboxylate lactonase activity",molecular_function
76966,GO:0047555,"Catalysis of the reaction: 3',5'-cyclic GMP + H2O = GMP + H+.","3',5'-cyclic-GMP phosphodiesterase activity",molecular_function
76967,GO:0047556,"Catalysis of the reaction: 3,4-dihydroxyphthalate + H+ = 3,4-dihydroxybenzoate + CO2.","3,4-dihydroxyphthalate decarboxylase activity",molecular_function
76968,GO:0047557,Catalysis of the reaction: 3-aci-nitropropanoate + H2O + O2 = 3-oxopropanoate + H2O2 + nitrite.,3-aci-nitropropanoate oxidase activity,molecular_function
76969,GO:0047558,Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H2O + H+.,3-cyanoalanine hydratase activity,molecular_function
76970,GO:0047559,"Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.",3-dehydro-L-gulonate 2-dehydrogenase activity,molecular_function
76971,GO:0047560,Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH.,3-dehydrosphinganine reductase activity,molecular_function
76972,GO:0047561,"Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.",3-hydroxyanthranilate oxidase activity,molecular_function
76973,GO:0047562,Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.,3-hydroxyaspartate aldolase activity,molecular_function
76974,GO:0047563,"Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O2 = 2,3-dihydroxybenzoate + A + H2O.",3-hydroxybenzoate 2-monooxygenase activity,molecular_function
76975,GO:0047564,"Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.",3-hydroxycyclohexanone dehydrogenase activity,molecular_function
76976,GO:0047565,Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + H+ + NADH.,3-hydroxypropionate dehydrogenase (NAD+) activity,molecular_function
76977,GO:0047566,"Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H+.",3-ketovalidoxylamine C-N-lyase activity,molecular_function
76978,GO:0047567,Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + H+ + NADPH.,3-methyleneoxindole reductase activity,molecular_function
76979,GO:0047568,Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.,3-oxo-5-beta-steroid 4-dehydrogenase activity,molecular_function
76980,GO:0047569,Catalysis of the reaction: 3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate.,3-oxoadipate CoA-transferase activity,molecular_function
76981,GO:0047570,Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.,3-oxoadipate enol-lactonase activity,molecular_function
76982,GO:0047571,Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.,3-oxosteroid 1-dehydrogenase activity,molecular_function
76983,GO:0047572,Catalysis of the reaction: 3-phospho-D-glycerate + H2O = D-glycerate + phosphate.,3-phosphoglycerate phosphatase activity,molecular_function
76984,GO:0047573,Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.,4-acetamidobutyrate deacetylase activity,molecular_function
76985,GO:0047574,Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate.,4-acetamidobutyryl-CoA deacetylase activity,molecular_function
76986,GO:0047575,"Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H+ = 5-oxo-4,5-dihydro-2-furylacetate + CO2.",4-carboxymuconolactone decarboxylase activity,molecular_function
76987,GO:0047576,Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+.,4-chlorobenzoate dehalogenase activity,molecular_function
76988,GO:0047577,Catalysis of the reaction: 4-hydroxybutanoate + NAD+ = H+ + NADH + succinate semialdehyde.,4-hydroxybutyrate dehydrogenase activity,molecular_function
76989,GO:0047578,Catalysis of the reaction: (4S)-4-hydroxy-L-glutamate + 2-oxoglutarate = (4R)-4-hydroxy-2-oxoglutarate + L-glutamate.,(4S)-4-hydroxy-L-glutamate:2-oxoglutarate transaminase activity,molecular_function
76990,GO:0047579,Catalysis of the reaction: (S)-4-hydroxymandelate + H+ + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2.,4-hydroxymandelate oxidase activity,molecular_function
76991,GO:0047580,Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.,4-hydroxyproline epimerase activity,molecular_function
76992,GO:0047581,Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH4 = 4-methylene-L-glutamine + AMP + diphosphate + 2 H+.,4-methyleneglutamate-ammonia ligase activity,molecular_function
76993,GO:0047582,Catalysis of the reaction: 4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH4.,4-methyleneglutaminase activity,molecular_function
76994,GO:0047583,"Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H2O = H+ + methanol + oxaloacetate.",4-methyloxaloacetate esterase activity,molecular_function
76995,GO:0047584,"Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H2O.",4-oxalmesaconate hydratase activity,molecular_function
76996,GO:0047585,Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate + H+.,4-pyridoxolactonase activity,molecular_function
76997,GO:0047586,Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.,5'-acylphosphoadenosine hydrolase activity,molecular_function
76998,GO:0047587,"Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H2O.",5-alpha-hydroxysteroid dehydratase activity,molecular_function
76999,GO:0047588,Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH4+.,5-aminopentanamidase activity,molecular_function
77000,GO:0047589,Catalysis of the reaction: 5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.,5-aminovalerate:2-oxoglutarate transaminase activity,molecular_function
77001,GO:0047590,Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.,5-dehydro-2-deoxygluconokinase activity,molecular_function
77002,GO:0047591,Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.,5-hydroxypentanoate CoA-transferase activity,molecular_function
77003,GO:0047592,Catalysis of the reaction: 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP+.,5-pyridoxate dioxygenase activity,molecular_function
77004,GO:0047593,Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate + H+.,6-acetylglucose deacetylase activity,molecular_function
77005,GO:0047594,Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H2O + H+ + scopolamine + succinate.,6-beta-hydroxyhyoscyamine epoxidase activity,molecular_function
77006,GO:0047595,"Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.",6-hydroxynicotinate reductase activity,molecular_function
77007,GO:0047596,Catalysis of the reaction: 6-methylsalicylate + H+ = 3-cresol + CO2.,6-methylsalicylate decarboxylase activity,molecular_function
77008,GO:0047597,"Catalysis of the reaction: 6-oxocineole + H+ + NADPH + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H2O + NADP+.",6-oxocineole dehydrogenase activity,molecular_function
77009,GO:0047598,Catalysis of the reaction: cholesterol + NADP+ = 7-dehydrocholesterol + H+ + NADPH.,7-dehydrocholesterol reductase activity,molecular_function
77010,GO:0047599,Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + 2 H+ + NADPH.,8-oxocoformycin reductase activity,molecular_function
77011,GO:0047600,Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.,abequosyltransferase activity,molecular_function
77012,GO:0047601,Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.,acetate kinase (diphosphate) activity,molecular_function
77013,GO:0047602,Catalysis of the reaction: acetoacetate + H+ = acetone + CO2.,acetoacetate decarboxylase activity,molecular_function
77014,GO:0047603,Catalysis of the reaction: acetoacetyl-CoA + H2O = acetoacetate + CoA + H+.,acetoacetyl-CoA hydrolase activity,molecular_function
77015,GO:0047604,Catalysis of the reaction: (S)-acetoin = (R)-acetoin.,acetoin racemase activity,molecular_function
77016,GO:0047605,Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.,acetolactate decarboxylase activity,molecular_function
77017,GO:0047606,Catalysis of the reaction: a (S)-hydroxynitrile = hydrogen cyanide + an aldehyde or ketone.,(S)-hydroxynitrile lyase activity,molecular_function
77018,GO:0047608,Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.,acetylindoxyl oxidase activity,molecular_function
77019,GO:0047609,Catalysis of the reaction: N-acetylputrescine + H2O = acetate + putrescine.,acetylputrescine deacetylase activity,molecular_function
77020,GO:0047610,Catalysis of the reaction: acetylsalicylate + H2O = acetate + H+ + salicylate.,acetylsalicylate deacetylase activity,molecular_function
77021,GO:0047611,Catalysis of the reaction: N(8)-acetylspermidine + H2O = acetate + spermidine.,acetylspermidine deacetylase activity,molecular_function
77022,GO:0047612,Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H+ + phosphate.,acid-CoA ligase (GDP-forming) activity,molecular_function
77023,GO:0047613,Catalysis of the reaction: cis-aconitate + H+ = CO2 + itaconate.,aconitate decarboxylase activity,molecular_function
77024,GO:0047614,Catalysis of the reaction: trans-aconitate = cis-aconitate.,aconitate delta-isomerase activity,molecular_function
77025,GO:0047615,Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.,actinomycin lactonase activity,molecular_function
77026,GO:0047616,"Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.",acyl-CoA dehydrogenase (NADP+) activity,molecular_function
77027,GO:0047617,Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.,fatty acyl-CoA hydrolase activity,molecular_function
77028,GO:0047618,Catalysis of the reaction: N(4)-benzoylagmatine + H2O = agmatine + benzoate.,acylagmatine amidase activity,molecular_function
77029,GO:0047619,Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.,acylcarnitine hydrolase activity,molecular_function
77030,GO:0047620,Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.,acylglycerol kinase activity,molecular_function
77031,GO:0047621,Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.,acylpyruvate hydrolase activity,molecular_function
77032,GO:0047622,Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.,adenosine nucleosidase activity,molecular_function
77033,GO:0047623,"Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH4+. Catalyzes the deamination of AMP, ADP or ATP.",adenosine-phosphate deaminase activity,molecular_function
77034,GO:0047624,Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = phosphate + ATP + H+.,adenosine-tetraphosphatase activity,molecular_function
77035,GO:0047625,Catalysis of the reaction: S-adenosyl-L-methionine = L-homoserine lactone + S-methyl-5'-thioadenosine.,S-adenosyl-L-methionine lyase activity,molecular_function
77036,GO:0047627,Catalysis of the reaction: 5'-adenylyl sulfate + H2O = AMP + 2 H+ + sulfate.,adenylylsulfatase activity,molecular_function
77037,GO:0047628,Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.,ADP-thymidine kinase activity,molecular_function
77038,GO:0047629,Catalysis of the reaction: ADP + H2O + H+ = IDP + NH4+.,ADP deaminase activity,molecular_function
77039,GO:0047630,Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H2O = 3-ADP-glycerate + phosphate.,ADP-phosphoglycerate phosphatase activity,molecular_function
77040,GO:0047631,Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.,ADP-ribose diphosphatase activity,molecular_function
77041,GO:0047632,Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH4+.,agmatine deiminase activity,molecular_function
77042,GO:0047633,Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H+.,agmatine kinase activity,molecular_function
77043,GO:0047634,Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H+.,agmatine N4-coumaroyltransferase activity,molecular_function
77044,GO:0047635,Catalysis of the reaction: L-alanine + a 2-oxocarboxylate = an L-alpha-amino acid + pyruvate.,L-alanine:oxo-acid transaminase activity,molecular_function
77045,GO:0047636,"Catalysis of the reaction: 2,2'-iminodipropanoate + H2O + NAD+ = L-alanine + H+ + NADH + pyruvate.",alanopine dehydrogenase activity,molecular_function
77046,GO:0047637,"Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala).",phosphatidylglycerol alanyltransferase activity,molecular_function
77047,GO:0047638,Catalysis of the reaction: albendazole + H+ + NADPH + O2 = albendazole S-oxide + H2O + NADP+.,albendazole monooxygenase activity,molecular_function
77048,GO:0047639,Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.,alcohol oxidase activity,molecular_function
77049,GO:0047640,Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.,aldose 1-dehydrogenase activity,molecular_function
77050,GO:0047641,Catalysis of the reaction: D-glucitol 6-phosphate + NADP+ = D-glucose 6-phosphate + H+ + NADPH.,aldose-6-phosphate reductase (NADPH) activity,molecular_function
77051,GO:0047642,Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.,aldose beta-D-fructosyltransferase activity,molecular_function
77052,GO:0047643,Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).,alginate synthase activity,molecular_function
77053,GO:0047644,"Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H+ + UDP.",alizarin 2-beta-glucosyltransferase activity,molecular_function
77054,GO:0047645,Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.,alkan-1-ol dehydrogenase (acceptor) activity,molecular_function
77055,GO:0047646,Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.,alkanal monooxygenase (FMN-linked) activity,molecular_function
77056,GO:0047647,Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H2O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.,alkylacetylglycerophosphatase activity,molecular_function
77057,GO:0047648,Catalysis of the reaction: N-methylhexanamide + H2O = hexanoate + methylammonium.,alkylamidase activity,molecular_function
77058,GO:0047649,Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H+.,alkylglycerol kinase activity,molecular_function
77059,GO:0047650,Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H+.,alkylglycerone kinase activity,molecular_function
77060,GO:0047651,Catalysis of the reaction: bromochloromethane + H2O = bromide + chloride + formaldehyde + 2 H+.,alkylhalidase activity,molecular_function
77061,GO:0047652,Catalysis of the reaction: allantoate + H2O + 2 H+ = (S)-2-ureidoglycine + NH4+ + CO2.,allantoate deiminase activity,molecular_function
77062,GO:0047653,Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.,allantoin racemase activity,molecular_function
77063,GO:0047654,Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.,alliin lyase activity,molecular_function
77064,GO:0047655,Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + H+ + NADPH.,allyl-alcohol dehydrogenase activity,molecular_function
77065,GO:0047656,"Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.","alpha,alpha-trehalose phosphorylase activity",molecular_function
77066,GO:0047657,"Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.","alpha-1,3-glucan synthase activity",molecular_function
77067,GO:0047658,Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.,alpha-amino-acid esterase activity,molecular_function
77068,GO:0047659,"Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.","alpha-santonin 1,2-reductase activity",molecular_function
77069,GO:0047660,Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea.,amidinoaspartase activity,molecular_function
77070,GO:0047661,Catalysis of the reaction: an L-amino acid = a D-amino acid.,amino-acid racemase activity,molecular_function
77071,GO:0047662,Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.,aminobenzoate decarboxylase activity,molecular_function
77072,GO:0047663,Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H+. This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.,aminoglycoside 6'-N-acetyltransferase activity,molecular_function
77073,GO:0047664,Catalysis of the reaction: 4-aminoimidazole + H2O + H+ = imidazol-4-one + NH4+.,aminoimidazolase activity,molecular_function
77074,GO:0047665,"Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.",aminolevulinate:pyruvate transaminase activity,molecular_function
77075,GO:0047666,Catalysis of the reaction: ATP + NH4 = ADP + 3 H+ + phosphoramidate.,ammonia kinase activity,molecular_function
77076,GO:0047667,Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.,AMP-thymidine kinase activity,molecular_function
77077,GO:0047668,Catalysis of the reaction: (R)-amygdalin + H2O = (R)-prunasin + D-glucose.,amygdalin beta-glucosidase activity,molecular_function
77078,GO:0047669,"Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).",amylosucrase activity,molecular_function
77079,GO:0047670,Catalysis of the reaction: anhydrotetracycline + H+ + NADPH + O2 = 12-dehydrotetracycline + H2O + NADP+.,anhydrotetracycline monooxygenase activity,molecular_function
77080,GO:0047671,Catalysis of the reaction: anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine = 2 AMP + cyclopeptine + 2 diphosphate + 2 H+ + S-adenosyl-L-homocysteine.,cyclopeptine synthase activity,molecular_function
77081,GO:0047672,Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.,anthranilate N-benzoyltransferase activity,molecular_function
77082,GO:0047673,Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.,anthranilate N-malonyltransferase activity,molecular_function
77083,GO:0047674,Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.,apiose 1-reductase activity,molecular_function
77084,GO:0047675,Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.,arabinonate dehydratase activity,molecular_function
77085,GO:0047676,Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H+.,arachidonate-CoA ligase activity,molecular_function
77086,GO:0047677,"Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.",arachidonate 8(R)-lipoxygenase activity,molecular_function
77087,GO:0047678,Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O.,arginine 2-monooxygenase activity,molecular_function
77088,GO:0047679,Catalysis of the reaction: L-arginine = D-arginine.,arginine racemase activity,molecular_function
77089,GO:0047680,Catalysis of the reaction: anilide + H2O = a carboxylate + aniline + H+.,aryl-acylamidase activity,molecular_function
77090,GO:0047681,Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.,aryl-alcohol dehydrogenase (NADP+) activity,molecular_function
77091,GO:0047682,Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.,aryl-alcohol oxidase activity,molecular_function
77092,GO:0047683,Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.,aryl-aldehyde dehydrogenase (NADP+) activity,molecular_function
77093,GO:0047684,Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.,arylamine glucosyltransferase activity,molecular_function
77094,GO:0047685,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.",amine sulfotransferase activity,molecular_function
77095,GO:0047686,Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.,arylsulfate sulfotransferase activity,molecular_function
77096,GO:0047688,Catalysis of the reaction: L-aspartate = L-alanine + CO2.,aspartate 4-decarboxylase activity,molecular_function
77097,GO:0047689,Catalysis of the reaction: L-aspartate = D-aspartate.,aspartate racemase activity,molecular_function
77098,GO:0047691,Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.,aspulvinone dimethylallyltransferase activity,molecular_function
77099,GO:0047692,Catalysis of the reaction: ATP + H2O + H+ = ITP + NH4+.,ATP deaminase activity,molecular_function
77100,GO:0047693,Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate.,ATP diphosphatase activity,molecular_function
77101,GO:0047694,Catalysis of the reaction: barbiturate + H2O = malonate + urea.,barbiturase activity,molecular_function
77102,GO:0047695,Catalysis of the reaction: benzoin = 2 benzaldehyde.,benzoin aldolase activity,molecular_function
77103,GO:0047696,Catalysis of the reaction: [beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H+.,beta-adrenergic receptor kinase activity,molecular_function
77104,GO:0047697,Catalysis of the reaction: (R)-beta-alanopine + H2O + NAD+ = beta-alanine + H+ + NADH + pyruvate.,beta-alanopine dehydrogenase activity,molecular_function
77105,GO:0047698,Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH4+.,beta-alanyl-CoA ammonia-lyase activity,molecular_function
77106,GO:0047699,"Catalysis of the reaction: H2O + nonane-4,6-dione = butanoate + H+ + pentan-2-one.",beta-diketone hydrolase activity,molecular_function
77107,GO:0047700,"Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.",beta-glucoside kinase activity,molecular_function
77108,GO:0047701,Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.,beta-L-arabinosidase activity,molecular_function
77109,GO:0047703,Catalysis of the reaction: 3-nitropropanoate + NADP+ = 3-nitroacrylate + H+ + NADPH.,beta-nitroacrylate reductase activity,molecular_function
77110,GO:0047704,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.",bile-salt sulfotransferase activity,molecular_function
77111,GO:0047705,Catalysis of the reaction: 2 bilirubin + O2 = 2 biliverdin + 2 H2O.,bilirubin oxidase activity,molecular_function
77112,GO:0047706,Catalysis of the reaction: dihydrobiochanin A + NADP+ = biochanin A + H+ + NADPH.,biochanin-A reductase activity,molecular_function
77113,GO:0047707,Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.,biotin-CoA ligase activity,molecular_function
77114,GO:0047708,Catalysis of the reaction: biotin amide + H2O = biotin + NH3.,biotinidase activity,molecular_function
77115,GO:0047709,Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H+.,bis(2-ethylhexyl)phthalate esterase activity,molecular_function
77116,GO:0047710,"Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP + 2 H+.",bis(5'-adenosyl)-triphosphatase activity,molecular_function
77117,GO:0047711,Catalysis of the reaction: blasticidin S + H2O + H+ = deaminohydroxyblasticidin S + NH4+.,blasticidin-S deaminase activity,molecular_function
77118,GO:0047712,Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.,Cypridina-luciferin 2-monooxygenase activity,molecular_function
77119,GO:0047713,Catalysis of the reaction: galactitol + NAD+ = D-tagatose + H+ + NADH.,galactitol 2-dehydrogenase activity,molecular_function
77120,GO:0047714,"Catalysis of the reaction: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H+.",galactolipase activity,molecular_function
77121,GO:0047715,Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H+.,hypotaurocyamine kinase activity,molecular_function
77122,GO:0047716,Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.,imidazole N-acetyltransferase activity,molecular_function
77123,GO:0047717,Catalysis of the reaction: H+ + imidazol-4-ylacetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD+.,imidazoleacetate 4-monooxygenase activity,molecular_function
77124,GO:0047718,Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.,indanol dehydrogenase activity,molecular_function
77125,GO:0047719,Catalysis of the reaction: indole + O2 = 2-formamidobenzaldehyde.,"indole 2,3-dioxygenase activity",molecular_function
77126,GO:0047720,Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O.,indoleacetaldoxime dehydratase activity,molecular_function
77127,GO:0047721,Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H+ + phosphate.,indoleacetate-lysine synthetase activity,molecular_function
77128,GO:0047722,Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD+ = 3-(indol-3-yl)pyruvate + H+ + NADH.,indolelactate dehydrogenase (NAD+) activity,molecular_function
77129,GO:0047723,Catalysis of the reaction: H2O + IMP = D-ribose 5-phosphate + hypoxanthine.,inosinate nucleosidase activity,molecular_function
77130,GO:0047724,Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.,inosine nucleosidase activity,molecular_function
77131,GO:0047725,"Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).",inulosucrase activity,molecular_function
77132,GO:0047726,Catalysis of the reaction: Fe3+ + Fe(II)-[cytochrome c] = Fe2+ + Fe(III)-[cytochrome c].,iron-cytochrome-c reductase activity,molecular_function
77133,GO:0047727,Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.,isobutyryl-CoA mutase activity,molecular_function
77134,GO:0047728,Catalysis of the reaction: carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.,carnitine 3-dehydrogenase activity,molecular_function
77135,GO:0047729,Catalysis of the reaction: carnitine + H+ = 2-methylcholine + CO2.,carnitine decarboxylase activity,molecular_function
77136,GO:0047730,Catalysis of the reaction: beta-alanine + L-histidine + ATP = carnosine + ADP + phosphate + H+.,carnosine synthase activity,molecular_function
77137,GO:0047731,"Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.",catechol oxidase (dimerizing) activity,molecular_function
77138,GO:0047732,"Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.",CDP-abequose epimerase activity,molecular_function
77139,GO:0047733,Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O.,"CDP-glucose 4,6-dehydratase activity",molecular_function
77140,GO:0047734,Catalysis of the reaction: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+.,CDP-glycerol diphosphatase activity,molecular_function
77141,GO:0047735,"Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.",cellobiose dehydrogenase (acceptor) activity,molecular_function
77142,GO:0047736,Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.,cellobiose epimerase activity,molecular_function
77143,GO:0047738,Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.,cellobiose phosphorylase activity,molecular_function
77144,GO:0047739,Catalysis of the reaction: cephalosporin C + H2O = acetate + deacetylcephalosporin C + H+.,cephalosporin-C deacetylase activity,molecular_function
77145,GO:0047740,Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.,cephalosporin-C:2-oxoglutarate transaminase activity,molecular_function
77146,GO:0047741,Catalysis of the reaction: benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+.,cetraxate benzylesterase activity,molecular_function
77147,GO:0047742,Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.,chenodeoxycholoyltaurine hydrolase activity,molecular_function
77148,GO:0047743,Catalysis of the reaction: chlordecone alcohol + NADP+ = chlordecone + H+ + NADPH.,chlordecone reductase activity,molecular_function
77149,GO:0047744,"Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H+.",chloridazon-catechol dioxygenase activity,molecular_function
77150,GO:0047745,Catalysis of the reaction: chlorogenate + H2O = (-)-quinate + cis-caffeate + H+.,chlorogenate hydrolase activity,molecular_function
77151,GO:0047746,Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.,chlorophyllase activity,molecular_function
77152,GO:0047747,"Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. This reaction is the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates.",cholate-CoA ligase activity,molecular_function
77153,GO:0047748,"Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 5 H+ + 3 O2 + 6 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 4 H2O + 6 oxidized [adrenodoxin].",cholestanetetraol 26-dehydrogenase activity,molecular_function
77154,GO:0047750,Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.,cholestenol delta-isomerase activity,molecular_function
77155,GO:0047751,Catalysis of the reaction: 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-delta(4)-steroid + H+ + NADPH.,3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity,molecular_function
77156,GO:0047753,Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.,choline-sulfatase activity,molecular_function
77157,GO:0047754,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H+.",choline sulfotransferase activity,molecular_function
77158,GO:0047755,Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.,isocitrate epimerase activity,molecular_function
77159,GO:0047756,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.",chondroitin 4-sulfotransferase activity,molecular_function
77160,GO:0047757,Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.,chondroitin-glucuronate 5-epimerase activity,molecular_function
77161,GO:0047758,Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H+.,ATP:2-methylpropanoate phosphotransferase activity,molecular_function
77162,GO:0047759,Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.,butanal dehydrogenase [NAD(P)+] activity,molecular_function
77163,GO:0047761,Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H+.,butyrate kinase activity,molecular_function
77164,GO:0047762,"Catalysis of the reaction: trans-caffeate + O2 = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H+.","caffeate 3,4-dioxygenase activity",molecular_function
77165,GO:0047763,"Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.",caffeate O-methyltransferase activity,molecular_function
77166,GO:0047766,Catalysis of the reaction: O-carbamoyl-L-serine + H2O + H+ = CO2 + 2 NH4 + pyruvate.,carbamoyl-serine ammonia-lyase activity,molecular_function
77167,GO:0047768,"Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.","carboxy-cis,cis-muconate cyclase activity",molecular_function
77168,GO:0047769,Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.,arogenate dehydratase activity,molecular_function
77169,GO:0047770,Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.,carboxylate reductase activity,molecular_function
77170,GO:0047771,Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H+.,carboxymethylhydantoinase activity,molecular_function
77171,GO:0047772,Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.,carboxymethyloxysuccinate lyase activity,molecular_function
77172,GO:0047773,Catalysis of the reaction: (R)-carnitinamide + H2O = (R)-carnitine + NH4.,carnitinamidase activity,molecular_function
77173,GO:0047774,"Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.",cis-2-enoyl-CoA reductase (NADPH) activity,molecular_function
77174,GO:0047775,Catalysis of the reaction: citramalate + acetyl-CoA = (3S)-citramalyl-CoA + acetate.,citramalate CoA-transferase activity,molecular_function
77175,GO:0047776,Catalysis of the reaction: S-citramalate = acetate + pyruvate.,citramalate lyase activity,molecular_function
77176,GO:0047777,Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.,(S)-citramalyl-CoA lyase activity,molecular_function
77177,GO:0047778,Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.,[citrate-(pro-3S)-lyase] thiolesterase activity,molecular_function
77178,GO:0047779,Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.,citrate-CoA ligase activity,molecular_function
77179,GO:0047781,Catalysis of the reaction: L-citrulline + H2O + 2 H+ = L-ornithine + NH4+ + CO2.,citrullinase activity,molecular_function
77180,GO:0047782,Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.,coniferin beta-glucosidase activity,molecular_function
77181,GO:0047783,Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.,corticosterone 18-monooxygenase activity,molecular_function
77182,GO:0047784,Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.,cortisol O-acetyltransferase activity,molecular_function
77183,GO:0047785,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H+.",cortisol sulfotransferase activity,molecular_function
77184,GO:0047787,"Catalysis of the reaction: a 3-oxo-5beta-steroid + NADP+ = a 3-oxo-Delta(4)-steroid + H+ + NADPH. The enzyme from human efficiently catalyzes the reduction of progesterone, androstenedione, 17alpha-hydroxyprogesterone and testosterone to 5beta-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7alpha,12alpha-dihydroxy-4-cholesten-3- one and 7alpha-hydroxy-4-cholesten-3-one can also act as substrates.",Delta4-3-oxosteroid 5beta-reductase activity,molecular_function
77185,GO:0047788,Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD+ = trans-2-coumarate + H+ + NADH.,2-coumarate reductase activity,molecular_function
77186,GO:0047789,Catalysis of the reaction: creatinine + H2O = creatine.,creatininase activity,molecular_function
77187,GO:0047790,Catalysis of the reaction: creatinine + H2O + H+ = N-methylhydantoin + NH4+.,creatinine deaminase activity,molecular_function
77188,GO:0047792,Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.,cyanohydrin beta-glucosyltransferase activity,molecular_function
77189,GO:0047793,Catalysis of the reaction: cycloeucalenol = obtusifoliol.,cycloeucalenol cycloisomerase activity,molecular_function
77190,GO:0047794,Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.,cyclohexadienyl dehydrogenase activity,molecular_function
77191,GO:0047795,"Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.","cyclohexane-1,2-diol dehydrogenase activity",molecular_function
77192,GO:0047796,"Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate + H+.","cyclohexane-1,3-dione hydrolase activity",molecular_function
77193,GO:0047797,Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.,cyclohexanone dehydrogenase activity,molecular_function
77194,GO:0047798,Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.,cyclomaltodextrinase activity,molecular_function
77195,GO:0047799,Catalysis of the reaction: cyclopentanone + H+ + NADPH + O2 = 5-valerolactone + H2O + NADP+.,cyclopentanone monooxygenase activity,molecular_function
77196,GO:0047800,Catalysis of the reaction: cysteamine + O2 = H+ + hypotaurine.,cysteamine dioxygenase activity,molecular_function
77197,GO:0047801,Catalysis of the reaction: L-cysteine + 2-oxoglutarate = 2-oxo-3-sulfanylpropanoate + L-glutamate.,L-cysteine:2-oxoglutarate transaminase activity,molecular_function
77198,GO:0047802,Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.,cysteine-conjugate:2-oxoglutarate transaminase activity,molecular_function
77199,GO:0047803,Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.,cysteine lyase activity,molecular_function
77200,GO:0047804,Catalysis of the reaction: S-substituted L-cysteine + H2O = a thiol + NH4+ + pyruvate.,cysteine-S-conjugate beta-lyase activity,molecular_function
77201,GO:0047805,"Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.",cytidylate cyclase activity,molecular_function
77202,GO:0047806,Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.,cytochrome-c3 hydrogenase activity,molecular_function
77203,GO:0047807,Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.,cytokinin 7-beta-glucosyltransferase activity,molecular_function
77204,GO:0047808,Catalysis of the reaction: D-tartrate = H2O + oxaloacetate.,D(-)-tartrate dehydratase activity,molecular_function
77205,GO:0047809,Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.,D-lactate dehydrogenase activity,molecular_function
77206,GO:0047810,Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.,D-alanine:2-oxoglutarate transaminase activity,molecular_function
77207,GO:0047811,Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4.,D-alanine gamma-glutamyltransferase activity,molecular_function
77208,GO:0047812,Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.,D-amino-acid N-acetyltransferase activity,molecular_function
77209,GO:0047813,Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.,D-arabinitol 4-dehydrogenase activity,molecular_function
77210,GO:0047814,Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.,D-arabinokinase activity,molecular_function
77211,GO:0047815,"Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate + H+.",D-arabinonolactonase activity,molecular_function
77212,GO:0047816,"Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.",D-arabinose 1-dehydrogenase (NAD+) activity,molecular_function
77213,GO:0047817,Catalysis of the reaction: D-arginine + H2O = D-ornithine + urea.,D-arginase activity,molecular_function
77214,GO:0047818,Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O.,D-fuconate dehydratase activity,molecular_function
77215,GO:0047819,"Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.",D-glutamate/D-aspartate oxidase activity,molecular_function
77216,GO:0047820,Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O.,D-glutamate cyclase activity,molecular_function
77217,GO:0047821,Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + H2O2 + NH4+.,D-glutamate oxidase activity,molecular_function
77218,GO:0047822,Catalysis of the reaction: H+ + hypotaurine + NADPH + O2 = H2O + NADP+ + taurine.,hypotaurine monooxygenase activity,molecular_function
77219,GO:0047823,"Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.",D-glutamyltransferase activity,molecular_function
77220,GO:0047824,Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.,D-iditol 2-dehydrogenase activity,molecular_function
77221,GO:0047825,Catalysis of the reaction: (R)-2-O-sulfolactate + H2O = (R)-lactate + H+ + sulfate.,D-lactate-2-sulfatase activity,molecular_function
77222,GO:0047826,"Catalysis of the reaction: D-lysine = (2R,5S)-2,5-diaminohexanoate and (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.","D-lysine 5,6-aminomutase activity",molecular_function
77223,GO:0047827,Catalysis of the reaction: D-lysopine + H2O + NADP+ = L-lysine + H+ + NADPH + pyruvate.,D-lysopine dehydrogenase activity,molecular_function
77224,GO:0047828,Catalysis of the reaction: D-lyxose = D-xylulose.,D-lyxose ketol-isomerase activity,molecular_function
77225,GO:0047829,Catalysis of the reaction: D-nopaline + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH + H+.,D-nopaline dehydrogenase activity,molecular_function
77226,GO:0047830,Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.,D-octopine dehydrogenase activity,molecular_function
77227,GO:0047831,"Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.","D-ornithine 4,5-aminomutase activity",molecular_function
77228,GO:0047832,"Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADPH.",D-pinitol dehydrogenase activity,molecular_function
77229,GO:0047833,Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.,D-sorbitol dehydrogenase (acceptor) activity,molecular_function
77230,GO:0047834,"Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.",D-threo-aldose 1-dehydrogenase activity,molecular_function
77231,GO:0047835,Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H+.,D-tryptophan N-acetyltransferase activity,molecular_function
77232,GO:0047836,Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H+.,D-tryptophan N-malonyltransferase activity,molecular_function
77233,GO:0047837,"Catalysis of the reaction: D-xylose + NADP+ = D-xylono-1,5-lactone + H+ + NADPH.",D-xylose 1-dehydrogenase (NADP+) activity,molecular_function
77234,GO:0047838,Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.,D-xylose 1-dehydrogenase (NAD+) activity,molecular_function
77235,GO:0047839,Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.,dATP(dGTP)-DNA purinetransferase activity,molecular_function
77236,GO:0047840,Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.,dCTP diphosphatase activity,molecular_function
77237,GO:0047841,Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H+.,dehydrogluconokinase activity,molecular_function
77238,GO:0047842,Catalysis of the reaction: 3-dehydro-L-gulonate + H+ = L-xylulose + CO2.,dehydro-L-gulonate decarboxylase activity,molecular_function
77239,GO:0047843,"Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).",dehydrogluconate dehydrogenase activity,molecular_function
77240,GO:0047845,Catalysis of the reaction: deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H+.,deoxylimonate A-ring-lactonase activity,molecular_function
77241,GO:0047846,Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.,deoxynucleotide 3'-phosphatase activity,molecular_function
77242,GO:0047847,Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.,deoxyuridine phosphorylase activity,molecular_function
77243,GO:0047849,Catalysis of the reaction: [(1->6)-alpha-D-glucosyl](n) + sucrose = [(1->6)-alpha-D-glucosyl](n+1) + D-fructose.,dextransucrase activity,molecular_function
77244,GO:0047850,"Catalysis of the reaction: meso-2,6-diaminopimelate + H2O + NADP+ = L-2-amino-6-oxopimelate + H+ + NADPH + NH4.",diaminopimelate dehydrogenase activity,molecular_function
77245,GO:0047851,Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA.,dicarboxylate-CoA ligase activity,molecular_function
77246,GO:0047852,Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.,diferric-transferrin reductase (NAD+) activity,molecular_function
77247,GO:0047853,"Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.",difructose-anhydride synthase activity,molecular_function
77248,GO:0047854,"Catalysis of the reaction: 1,4-diguanidinobutane + H2O = agmatine + urea.",diguanidinobutanase activity,molecular_function
77249,GO:0047855,Catalysis of the reaction: dihydrobunolol + NADP+ = bunolol + H+ + NADPH.,dihydrobunolol dehydrogenase activity,molecular_function
77250,GO:0047856,"Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.",dihydrocoumarin hydrolase activity,molecular_function
77251,GO:0047857,"Catalysis of the reaction: 5,6-dihydrouracil + O2 = H2O2 + uracil.",dihydrouracil oxidase activity,molecular_function
77252,GO:0047858,Catalysis of the reaction: dihydroxyfumarate + H+ = 2-hydroxy-3-oxopropanoate + CO2.,dihydroxyfumarate decarboxylase activity,molecular_function
77253,GO:0047860,"Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H+ + NADH.",diiodophenylpyruvate reductase (NAD+) activity,molecular_function
77254,GO:0047861,"Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.","3,5-diiodo-L-tyrosine:2-oxoglutarate transaminase activity",molecular_function
77255,GO:0047862,Catalysis of the reaction: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H+.,diisopropyl-fluorophosphatase activity,molecular_function
77256,GO:0047863,Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.,dimethylallylcistransferase activity,molecular_function
77257,GO:0047864,"Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.",dimethylaniline-N-oxide aldolase activity,molecular_function
77258,GO:0047865,"Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.",dimethylglycine dehydrogenase activity,molecular_function
77259,GO:0047866,"Catalysis of the reaction: N,N-dimethylglycine + H2O + O2 = formaldehyde + H2O2 + sarcosine.",dimethylglycine oxidase activity,molecular_function
77260,GO:0047867,"Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH.",dimethylmalate dehydrogenase activity,molecular_function
77261,GO:0047868,"Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O.",dimethylmaleate hydratase activity,molecular_function
77262,GO:0047869,"Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H+.",dimethylpropiothetin dethiomethylase activity,molecular_function
77263,GO:0047870,Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H+.,discadenine synthase activity,molecular_function
77264,GO:0047871,"Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + H+ + sulfate.",disulfoglucosamine-6-sulfatase activity,molecular_function
77265,GO:0047872,Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.,dolichol O-acyltransferase activity,molecular_function
77266,GO:0047873,Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.,dolichyl-phosphatase activity,molecular_function
77267,GO:0047874,"Catalysis of the reaction: a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H+.",dolichyldiphosphatase activity,molecular_function
77268,GO:0047875,Catalysis of the reaction: Ecdysone + O2 = 3-dehydroecdysone + H2O2.,ecdysone oxidase activity,molecular_function
77269,GO:0047876,Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.,endoglycosylceramidase activity,molecular_function
77270,GO:0047877,"Catalysis of the reaction: (1R,2S)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H+ + NADH.",ephedrine dehydrogenase activity,molecular_function
77271,GO:0047878,Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H+.,erythritol kinase activity,molecular_function
77272,GO:0047879,Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.,erythronolide synthase activity,molecular_function
77273,GO:0047880,Catalysis of the reaction: D-threitol + NADP+ = D-erythrulose + H+ + NADPH.,erythrulose reductase activity,molecular_function
77274,GO:0047881,Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.,estradiol 17-alpha-dehydrogenase [NAD(P)+] activity,molecular_function
77275,GO:0047882,Catalysis of the reaction: AH(2) + estradiol-17beta + O2 = 6beta-hydroxyestradiol-17beta + A + H2O.,estradiol 6-beta-monooxygenase activity,molecular_function
77276,GO:0047883,Catalysis of the reaction: ethanolamine + O2 + H2O = glycolaldehyde + H2O2 + NH4+.,ethanolamine oxidase activity,molecular_function
77277,GO:0047884,Catalysis of the reaction: FAD + H2O = AMP + FMN.,FAD diphosphatase activity,molecular_function
77278,GO:0047885,"Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.",farnesol 2-isomerase activity,molecular_function
77279,GO:0047886,"Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + H+ + NADPH.",farnesol dehydrogenase activity,molecular_function
77280,GO:0047887,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.",farnesyl diphosphate kinase activity,molecular_function
77281,GO:0047888,Catalysis of the reaction: 2 H2O2 + H+ + palmitate = CO2 + 3 H2O + pentadecanal.,fatty acid peroxidase activity,molecular_function
77282,GO:0047889,Catalysis of the reaction: nitrite + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = nitrate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H+.,ferredoxin-nitrate reductase activity,molecular_function
77283,GO:0047890,Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.,flavanone 4-reductase activity,molecular_function
77284,GO:0047891,"Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.",flavone 7-O-beta-glucosyltransferase activity,molecular_function
77285,GO:0047892,"Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.",flavone apiosyltransferase activity,molecular_function
77286,GO:0047893,Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.,flavonol 3-O-glucosyltransferase activity,molecular_function
77287,GO:0047894,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H+ + quercetin 3-sulfate.",flavonol 3-sulfotransferase activity,molecular_function
77288,GO:0047895,Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.,formaldehyde dismutase activity,molecular_function
77289,GO:0047896,Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.,formaldehyde transketolase activity,molecular_function
77290,GO:0047897,"Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H+ + phosphate.",formate-dihydrofolate ligase activity,molecular_function
77291,GO:0047898,Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.,formate dehydrogenase (cytochrome) activity,molecular_function
77292,GO:0047899,Catalysis of the reaction: formate + NADP+ = CO2 + NADPH.,formate dehydrogenase (NADP+) activity,molecular_function
77293,GO:0047900,Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H+.,formate kinase activity,molecular_function
77294,GO:0047902,Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.,formylaspartate deformylase activity,molecular_function
77295,GO:0047903,Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.,fructose 5-dehydrogenase (NADP+) activity,molecular_function
77296,GO:0047904,Catalysis of the reaction: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol.,fructose 5-dehydrogenase activity,molecular_function
77297,GO:0047905,Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.,fructose-6-phosphate phosphoketolase activity,molecular_function
77298,GO:0047906,"Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.",fucosterol-epoxide lyase activity,molecular_function
77299,GO:0047907,Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.,furylfuramide isomerase activity,molecular_function
77300,GO:0047908,Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.,fusarinine-C ornithinesterase activity,molecular_function
77301,GO:0047909,Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.,galactolipid O-acyltransferase activity,molecular_function
77302,GO:0047910,Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.,galactose 1-dehydrogenase (NADP+) activity,molecular_function
77303,GO:0047911,Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.,"galacturan 1,4-alpha-galacturonidase activity",molecular_function
77304,GO:0047912,Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.,galacturonokinase activity,molecular_function
77305,GO:0047913,Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.,gallate 1-beta-glucosyltransferase activity,molecular_function
77306,GO:0047914,Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.,gamma-glutamylhistamine synthase activity,molecular_function
77307,GO:0047915,"Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.",ganglioside galactosyltransferase activity,molecular_function
77308,GO:0047916,Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.,GDP-6-deoxy-D-talose 4-dehydrogenase activity,molecular_function
77309,GO:0047917,Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.,GDP-glucosidase activity,molecular_function
77310,GO:0047918,Catalysis of the reaction: GDP-mannose = GDP-L-galactose.,"GDP-mannose 3,5-epimerase activity",molecular_function
77311,GO:0047919,Catalysis of the reaction: GDP-alpha-D-mannose + H2O + 2 NAD+ = GDP-D-mannuronate + 3 H+ + 2 NADH.,GDP-mannose 6-dehydrogenase activity,molecular_function
77312,GO:0047920,"Catalysis of the reaction: geissoschizine + NADP+ = 4,21-dehydrogeissoschizine + H+ + NADPH.",geissoschizine dehydrogenase activity,molecular_function
77313,GO:0047921,Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.,aminoglycoside 2'-N-acetyltransferase activity,molecular_function
77314,GO:0047922,"Catalysis of the reaction: 2,5-dihydroxybenzoate + O2 = 3-maleylpyruvate + H+.","gentisate 1,2-dioxygenase activity",molecular_function
77315,GO:0047923,"Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.",gentisate decarboxylase activity,molecular_function
77316,GO:0047924,Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.,geraniol dehydrogenase activity,molecular_function
77317,GO:0047925,Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H+ + phosphate.,geranoyl-CoA carboxylase activity,molecular_function
77318,GO:0047926,Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.,geranyl-diphosphate cyclase activity,molecular_function
77319,GO:0047928,Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.,gibberellin beta-D-glucosyltransferase activity,molecular_function
77320,GO:0047929,Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.,gluconate dehydratase activity,molecular_function
77321,GO:0047930,Catalysis of the reaction: 2-amino-2-deoxy-D-gluconate = 2-dehydro-3-deoxy-D-gluconate + NH4+.,glucosaminate ammonia-lyase activity,molecular_function
77322,GO:0047931,Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate + H+.,glucosamine kinase activity,molecular_function
77323,GO:0047932,Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.,glucosamine N-acetyltransferase activity,molecular_function
77324,GO:0047933,"Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H+.","glucose-1,6-bisphosphate synthase activity",molecular_function
77325,GO:0047934,"Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.",glucose 1-dehydrogenase (NAD+) activity,molecular_function
77326,GO:0047935,"Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.",glucose 1-dehydrogenase (NADP+) activity,molecular_function
77327,GO:0047936,"Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.",glucose 1-dehydrogenase [NAD(P)+] activity,molecular_function
77328,GO:0047937,"Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.",glucose-1-phosphate phosphodismutase activity,molecular_function
77329,GO:0047938,Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.,glucose-6-phosphate 1-epimerase activity,molecular_function
77330,GO:0047939,Catalysis of the reaction: L-gulonate + NADP+ = D-glucuronate + H+ + NADPH.,L-glucuronate reductase activity,molecular_function
77331,GO:0047940,Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H+.,glucuronokinase activity,molecular_function
77332,GO:0047941,"Catalysis of the reaction: L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + H+ + NADPH.",glucuronolactone reductase activity,molecular_function
77333,GO:0047942,Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H+ + phosphate.,glutamate-ethylamine ligase activity,molecular_function
77334,GO:0047943,Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H+ + phosphate.,glutamate-methylamine ligase activity,molecular_function
77335,GO:0047945,Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.,L-glutamine:pyruvate transaminase activity,molecular_function
77336,GO:0047946,Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.,L-glutamine N-acyltransferase activity,molecular_function
77337,GO:0047947,Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.,glutamine N-phenylacetyltransferase activity,molecular_function
77338,GO:0047948,Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H+ + phosphate.,glutarate-CoA ligase activity,molecular_function
77339,GO:0047950,Catalysis of the reaction: 2 glutathione + O2 = glutathione disulfide + H2O2.,glutathione oxidase activity,molecular_function
77340,GO:0047951,Catalysis of the reaction: S-acylglutathione + H2O = a carboxylate + glutathione + H+.,glutathione thiolesterase activity,molecular_function
77341,GO:0047952,Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.,glycerol-3-phosphate dehydrogenase [NAD(P)+] activity,molecular_function
77342,GO:0047953,Catalysis of the reaction: glycerol + NADP+ = dihydroxyacetone + NADPH + H+.,glycerol 2-dehydrogenase (NADP+) activity,molecular_function
77343,GO:0047954,Catalysis of the reaction: glycerol 2-phosphate + H2O = glycerol + phosphate.,glycerol-2-phosphatase activity,molecular_function
77344,GO:0047955,Catalysis of the reaction: A + glycerol = AH(2) + glycerone.,glycerol dehydrogenase (acceptor) activity,molecular_function
77345,GO:0047956,Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.,glycerol dehydrogenase (NADP+) activity,molecular_function
77346,GO:0047957,Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O.,4'-methoxyisoflavone 2'-hydroxylase activity,molecular_function
77347,GO:0047958,Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.,glycine:2-oxoglutarate transaminase activity,molecular_function
77348,GO:0047959,Catalysis of the reaction: 2 Fe(III)-[cytochrome c] + glycine + H2O = 2 Fe(II)-[cytochrome c] + glyoxylate + NH4+ + 2 H+.,glycine dehydrogenase (cytochrome) activity,molecular_function
77349,GO:0047960,Catalysis of the reaction: glycine + NAD+ + H2O = glyoxylate + NH4+ + NADH + H+.,glycine dehydrogenase (NAD+) activity,molecular_function
77350,GO:0047961,Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine.,glycine N-acyltransferase activity,molecular_function
77351,GO:0047962,Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H+.,glycine N-benzoyltransferase activity,molecular_function
77352,GO:0047963,Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate.,glycine N-choloyltransferase activity,molecular_function
77353,GO:0047964,Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.,glyoxylate reductase (NADH) activity,molecular_function
77354,GO:0047965,Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.,glycoprotein O-fatty-acyltransferase activity,molecular_function
77355,GO:0047966,Catalysis of the reaction: D-glucose 6-sulfate + H2O = D-glucose + H+ + sulfate.,glycosulfatase activity,molecular_function
77356,GO:0047967,Catalysis of the reaction: glycyrrhizate + H2O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.,glycyrrhizinate beta-glucuronidase activity,molecular_function
77357,GO:0047968,Catalysis of the reaction: CoA + glyoxylate + NADP+ = H+ + NADPH + oxalyl-CoA.,"glyoxylate dehydrogenase (acylating, NADP+) activity",molecular_function
77358,GO:0047969,Catalysis of the reaction: glyoxylate + H2O + O2 = H2O2 + H+ + oxalate.,glyoxylate oxidase activity,molecular_function
77359,GO:0047970,Catalysis of the reaction: guanidinoacetate + H2O = glycine + urea.,guanidinoacetase activity,molecular_function
77360,GO:0047971,Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.,guanidinobutyrase activity,molecular_function
77361,GO:0047972,Catalysis of the reaction: 3-guanidinopropanoate + H2O = beta-alanine + urea.,guanidinopropionase activity,molecular_function
77362,GO:0047973,Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H+ + phosphoguanidinoacetate.,guanidinoacetate kinase activity,molecular_function
77363,GO:0047974,Catalysis of the reaction: guanosine + H2O + H+ = xanthosine + NH4+.,guanosine deaminase activity,molecular_function
77364,GO:0047975,Catalysis of the reaction: guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine.,guanosine phosphorylase activity,molecular_function
77365,GO:0047976,Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H+.,hamamelose kinase activity,molecular_function
77366,GO:0047977,"Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.",hepoxilin-epoxide hydrolase activity,molecular_function
77367,GO:0047978,Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.,hexadecanol dehydrogenase (NAD+) activity,molecular_function
77368,GO:0047979,"Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.",hexose oxidase activity,molecular_function
77369,GO:0047980,Catalysis of the reaction: N-benzoylglycine + H2O = benzoate + glycine.,hippurate hydrolase activity,molecular_function
77370,GO:0047981,Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.,L-histidine N-acetyltransferase activity,molecular_function
77371,GO:0047982,Catalysis of the reaction: L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4+ + H+.,homocysteine desulfhydrase activity,molecular_function
77372,GO:0047983,Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H+ + phosphate.,homoglutathione synthase activity,molecular_function
77373,GO:0047985,Catalysis of the reaction: H2 + NAD+ = H+ + NADH.,hydrogen dehydrogenase activity,molecular_function
77374,GO:0047986,Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.,hydrogen-sulfide S-acetyltransferase activity,molecular_function
77375,GO:0047988,Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.,hydroxyacid-oxoacid transhydrogenase activity,molecular_function
77376,GO:0047989,Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H2O = 2 (R)-3-hydroxybutanoate + H+.,hydroxybutyrate-dimer hydrolase activity,molecular_function
77377,GO:0047990,Catalysis of the reaction: 3-hydroxy-L-glutamate + H+ = 4-amino-3-hydroxybutanoate + CO2.,hydroxyglutamate decarboxylase activity,molecular_function
77378,GO:0047991,Catalysis of the reaction: hydroxylamine + O2 = H2O + H+ + nitrite.,hydroxylamine oxidase activity,molecular_function
77379,GO:0047992,Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H+.,hydroxylysine kinase activity,molecular_function
77380,GO:0047993,Catalysis of the reaction: hydroxymalonate + NAD+ = H+ + NADH + oxomalonate.,hydroxymalonate dehydrogenase activity,molecular_function
77381,GO:0047994,Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H+.,hydroxymethylglutaryl-CoA hydrolase activity,molecular_function
77382,GO:0047995,Catalysis of the reaction: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(P)+ = 3-(4-hydroxyphenyl)pyruvate + NAD(P)H + H+.,(2R)-hydroxyphenylpyruvate reductase [NAD(P)H] activity,molecular_function
77383,GO:0047996,Catalysis of the reaction: (2S)-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2.,(2S)-2-hydroxyphytanate oxidase activity,molecular_function
77384,GO:0047997,Catalysis of the reaction: 3-hydroxypyruvate + H+ = CO2 + glycolaldehyde.,hydroxypyruvate decarboxylase activity,molecular_function
77385,GO:0047998,Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate.,hyoscyamine (6S)-dioxygenase activity,molecular_function
77386,GO:0047999,Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = 2 H+ + hyponitrous acid + 2 NADH.,hyponitrite reductase (NADH) activity,molecular_function
77387,GO:0048000,Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.,isoflavone 3'-hydroxylase activity,molecular_function
77388,GO:0048001,Catalysis of the reaction: D-erythrose 4-phosphate + H2O + NAD+ = 4-phospho-D-erythronate + 2 H+ + NADH.,erythrose-4-phosphate dehydrogenase (NAD+) activity,molecular_function
77389,GO:0048002,"The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.",antigen processing and presentation of peptide antigen,biological_process
77390,GO:0048003,"The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.",antigen processing and presentation of lipid antigen via MHC class Ib,biological_process
77391,GO:0048006,"The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.","antigen processing and presentation, endogenous lipid antigen via MHC class Ib",biological_process
77392,GO:0048007,"The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.","antigen processing and presentation, exogenous lipid antigen via MHC class Ib",biological_process
77393,GO:0048008,"The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",platelet-derived growth factor receptor signaling pathway,biological_process
77394,GO:0048009,"The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",insulin-like growth factor receptor signaling pathway,biological_process
77395,GO:0048010,"The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",vascular endothelial growth factor receptor signaling pathway,biological_process
77396,GO:0048011,"The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.",neurotrophin TRK receptor signaling pathway,biological_process
77397,GO:0048012,"The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",hepatocyte growth factor receptor signaling pathway,biological_process
77398,GO:0048013,"The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",ephrin receptor signaling pathway,biological_process
77399,GO:0048014,"The series of molecular signals initiated by an angiopoietin binding to the Tie receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.",Tie signaling pathway,biological_process
77400,GO:0048015,The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.,phosphatidylinositol-mediated signaling,biological_process
77401,GO:0048018,The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same cell that expresses the receptor. Ligands may also be expressed at the plasma membrane of an adjacent cell (e.g. Notch ligands) or be secreted and diffuse extracellularly from their point of origin to the receiving cell (e.g. interleukins).,receptor ligand activity,molecular_function
77402,GO:0048019,The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.,receptor antagonist activity,molecular_function
77403,GO:0048020,Binding to a CCR chemokine receptor.,CCR chemokine receptor binding,molecular_function
77404,GO:0048021,"Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.",regulation of melanin biosynthetic process,biological_process
77405,GO:0048022,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.",negative regulation of melanin biosynthetic process,biological_process
77406,GO:0048023,Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.,positive regulation of melanin biosynthetic process,biological_process
77407,GO:0048024,"Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.","regulation of mRNA splicing, via spliceosome",biological_process
77408,GO:0048025,"Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.","negative regulation of mRNA splicing, via spliceosome",biological_process
77409,GO:0048026,Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.,"positive regulation of mRNA splicing, via spliceosome",biological_process
77410,GO:0048027,Binding to an mRNA molecule at its 5' untranslated region.,mRNA 5'-UTR binding,molecular_function
77411,GO:0048028,"Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.",galacturonan binding,molecular_function
77412,GO:0048029,Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.,monosaccharide binding,molecular_function
77413,GO:0048030,Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units.,disaccharide binding,molecular_function
77414,GO:0048031,Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.,trisaccharide binding,molecular_function
77415,GO:0048032,"Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.",galacturonate binding,molecular_function
77416,GO:0048034,"The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.",heme O biosynthetic process,biological_process
77417,GO:0048035,"The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.",heme O catabolic process,biological_process
77418,GO:0048036,"The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.",central complex development,biological_process
77419,GO:0048038,"Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.",quinone binding,molecular_function
77420,GO:0048039,"Binding to ubiquinone, a quinone derivative with a tail of isoprene units.",ubiquinone binding,molecular_function
77421,GO:0048040,Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = CO2 + UDP-alpha-D-xylose.,UDP-glucuronate decarboxylase activity,molecular_function
77422,GO:0048041,"The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.",focal adhesion assembly,biological_process
77423,GO:0048046,"The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.",apoplast,cellular_component
77424,GO:0048047,"The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.","mating behavior, sex discrimination",biological_process
77425,GO:0048048,The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.,embryonic eye morphogenesis,biological_process
77426,GO:0048050,"The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.",post-embryonic eye morphogenesis,biological_process
77427,GO:0048052,The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.,R1/R6 cell differentiation,biological_process
77428,GO:0048053,"The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.",R1/R6 development,biological_process
77429,GO:0048054,The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.,R2/R5 cell differentiation,biological_process
77430,GO:0048055,"The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.",R2/R5 development,biological_process
77431,GO:0048056,The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.,R3/R4 cell differentiation,biological_process
77432,GO:0048057,"The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.",R3/R4 development,biological_process
77433,GO:0048058,"The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.",compound eye corneal lens development,biological_process
77434,GO:0048060,The directed movement of a motile cell or organism away from the source of gravity.,negative gravitaxis,biological_process
77435,GO:0048061,The directed movement of a motile cell or organism towards the source of gravity.,positive gravitaxis,biological_process
77436,GO:0048065,The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.,"male courtship behavior, veined wing extension",biological_process
77437,GO:0048066,"The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.",developmental pigmentation,biological_process
77438,GO:0048067,Establishment of a pattern of pigment in the cuticle of an organism.,cuticle pigmentation,biological_process
77439,GO:0048069,Establishment of a pattern of pigment in the eye of an organism.,eye pigmentation,biological_process
77440,GO:0048070,"Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.",regulation of developmental pigmentation,biological_process
77441,GO:0048071,Establishment of a pattern of pigment in one sex that is not observed in the other sex.,sex-specific pigmentation,biological_process
77442,GO:0048072,Establishment of a pattern of pigment in the compound eye.,compound eye pigmentation,biological_process
77443,GO:0048073,"Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.",regulation of eye pigmentation,biological_process
77444,GO:0048074,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.",negative regulation of eye pigmentation,biological_process
77445,GO:0048075,"Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.",positive regulation of eye pigmentation,biological_process
77446,GO:0048076,"Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.",regulation of compound eye pigmentation,biological_process
77447,GO:0048077,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.",negative regulation of compound eye pigmentation,biological_process
77448,GO:0048078,"Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.",positive regulation of compound eye pigmentation,biological_process
77449,GO:0048079,"Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.",regulation of cuticle pigmentation,biological_process
77450,GO:0048080,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.",negative regulation of cuticle pigmentation,biological_process
77451,GO:0048081,"Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.",positive regulation of cuticle pigmentation,biological_process
77452,GO:0048082,"Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.",regulation of adult chitin-containing cuticle pigmentation,biological_process
77453,GO:0048083,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.",negative regulation of adult chitin-containing cuticle pigmentation,biological_process
77454,GO:0048084,"Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.",positive regulation of adult chitin-containing cuticle pigmentation,biological_process
77455,GO:0048085,Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.,adult chitin-containing cuticle pigmentation,biological_process
77456,GO:0048086,"Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.",negative regulation of developmental pigmentation,biological_process
77457,GO:0048087,"Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.",positive regulation of developmental pigmentation,biological_process
77458,GO:0048088,"Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.",regulation of male pigmentation,biological_process
77459,GO:0048089,"Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.",regulation of female pigmentation,biological_process
77460,GO:0048090,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.",negative regulation of female pigmentation,biological_process
77461,GO:0048091,"Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.",positive regulation of female pigmentation,biological_process
77462,GO:0048092,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.",negative regulation of male pigmentation,biological_process
77463,GO:0048093,"Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.",positive regulation of male pigmentation,biological_process
77464,GO:0048094,Establishment of a pattern of pigment in males.,male pigmentation,biological_process
77465,GO:0048095,Establishment of a pattern of pigment in females.,female pigmentation,biological_process
77466,GO:0048098,"The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.",antennal joint development,biological_process
77467,GO:0048099,"Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.","anterior/posterior lineage restriction, imaginal disc",biological_process
77468,GO:0048100,"The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.",wing disc anterior/posterior pattern formation,biological_process
77469,GO:0048101,"Catalysis of the reactions: nucleoside 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.","calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity",molecular_function
77470,GO:0048102,"A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.",autophagic cell death,biological_process
77471,GO:0048103,"The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.",somatic stem cell division,biological_process
77472,GO:0048104,"Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.",establishment of body hair or bristle planar orientation,biological_process
77473,GO:0048105,"Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.",establishment of body hair planar orientation,biological_process
77474,GO:0048106,"Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.",establishment of thoracic bristle planar orientation,biological_process
77475,GO:0048107,"The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.",4-amino-3-isothiazolidinone biosynthetic process,biological_process
77476,GO:0048132,"The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.",female germ-line stem cell asymmetric division,biological_process
77477,GO:0048133,"The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.",male germ-line stem cell asymmetric division,biological_process
77478,GO:0048134,Formation of a group of interconnected cells derived from a single gonial founder cell.,germ-line cyst formation,biological_process
77479,GO:0048135,Formation of a group of interconnected cells derived from a single female gonial founder cell.,female germ-line cyst formation,biological_process
77480,GO:0048136,Formation of a group of interconnected cells derived from a single male gonial founder cell.,male germ-line cyst formation,biological_process
77481,GO:0048137,The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.,spermatocyte division,biological_process
77482,GO:0048138,Formation of a single follicular epithelium around the germ-line derived cells of a cyst.,germ-line cyst encapsulation,biological_process
77483,GO:0048139,Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.,female germ-line cyst encapsulation,biological_process
77484,GO:0048140,Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.,male germ-line cyst encapsulation,biological_process
77485,GO:0048142,"The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.",germarium-derived cystoblast division,biological_process
77486,GO:0048143,"A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",astrocyte activation,biological_process
77487,GO:0048144,"The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.",fibroblast proliferation,biological_process
77488,GO:0048145,"Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.",regulation of fibroblast proliferation,biological_process
77489,GO:0048146,"Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.",positive regulation of fibroblast proliferation,biological_process
77490,GO:0048147,"Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.",negative regulation of fibroblast proliferation,biological_process
77491,GO:0048148,Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.,behavioral response to cocaine,biological_process
77492,GO:0048149,Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.,behavioral response to ethanol,biological_process
77493,GO:0048150,Any process that results in a change in the behavior of an organism as a result of an ether stimulus.,behavioral response to ether,biological_process
77494,GO:0048156,"Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.",tau protein binding,molecular_function
77495,GO:0048158,The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.,oogonium stage,biological_process
77496,GO:0048159,The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.,primary oocyte stage,biological_process
77497,GO:0048160,The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.,primary follicle stage,biological_process
77498,GO:0048161,The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.,double layer follicle stage,biological_process
77499,GO:0048162,The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.,multi-layer follicle stage,biological_process
77500,GO:0048163,The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.,scattered antral spaces stage,biological_process
77501,GO:0048164,The stage in oogenesis when the antral spaces become distinct and the first polar body forms.,distinct antral spaces stage,biological_process
77502,GO:0048165,The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.,fused antrum stage,biological_process
77503,GO:0048166,The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.,mature follicle stage,biological_process
77504,GO:0048167,"A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.",regulation of synaptic plasticity,biological_process
77505,GO:0048168,"A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.",regulation of neuronal synaptic plasticity,biological_process
77506,GO:0048169,"A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.",regulation of long-term neuronal synaptic plasticity,biological_process
77507,GO:0048170,"A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.",positive regulation of long-term neuronal synaptic plasticity,biological_process
77508,GO:0048171,"A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.",negative regulation of long-term neuronal synaptic plasticity,biological_process
77509,GO:0048172,"A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.",regulation of short-term neuronal synaptic plasticity,biological_process
77510,GO:0048173,"A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.",positive regulation of short-term neuronal synaptic plasticity,biological_process
77511,GO:0048174,"A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.",negative regulation of short-term neuronal synaptic plasticity,biological_process
77512,GO:0048179,"A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.",activin receptor complex,cellular_component
77513,GO:0048180,"A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.",activin complex,cellular_component
77514,GO:0048183,"A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.",activin AB complex,cellular_component
77515,GO:0048185,"Binding to activin, a dimer of inhibin-beta subunits.",activin binding,molecular_function
77516,GO:0048188,"A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.",Set1C/COMPASS complex,cellular_component
77517,GO:0048189,"A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1.",Lid2 complex,cellular_component
77518,GO:0048190,"The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.",wing disc dorsal/ventral pattern formation,biological_process
77519,GO:0048193,"The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.",Golgi vesicle transport,biological_process
77520,GO:0048194,"The evagination of the Golgi membrane, resulting in formation of a vesicle.",Golgi vesicle budding,biological_process
77521,GO:0048195,"The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.",Golgi membrane priming complex assembly,biological_process
77522,GO:0048197,"The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.",Golgi membrane coat protein complex assembly,biological_process
77523,GO:0048198,The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.,Golgi vesicle bud deformation and release,biological_process
77524,GO:0048200,The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.,Golgi transport vesicle coating,biological_process
77525,GO:0048202,"The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.",clathrin coating of Golgi vesicle,biological_process
77526,GO:0048205,"The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.",COPI coating of Golgi vesicle,biological_process
77527,GO:0048208,"The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.",COPII vesicle coat assembly,biological_process
77528,GO:0048210,The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.,Golgi vesicle fusion to target membrane,biological_process
77529,GO:0048212,"The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.",Golgi vesicle uncoating,biological_process
77530,GO:0048214,"Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.",regulation of Golgi vesicle fusion to target membrane,biological_process
77531,GO:0048215,"Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.",positive regulation of Golgi vesicle fusion to target membrane,biological_process
77532,GO:0048216,"Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.",negative regulation of Golgi vesicle fusion to target membrane,biological_process
77533,GO:0048217,"The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.",pectic matrix,cellular_component
77534,GO:0048219,"The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.",inter-Golgi cisterna vesicle-mediated transport,biological_process
77535,GO:0048222,An extracellular matrix part that consists of cross-linked glycoproteins.,glycoprotein network,cellular_component
77536,GO:0048223,"Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.",hemicellulose network,cellular_component
77537,GO:0048224,"An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, an...",lignin network,cellular_component
77538,GO:0048225,"An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.",suberin network,cellular_component
77539,GO:0048226,"Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.",Casparian strip,cellular_component
77540,GO:0048227,Transport of a vesicle from the plasma membrane to the endosome.,plasma membrane to endosome transport,biological_process
77541,GO:0048229,"The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.",gametophyte development,biological_process
77542,GO:0048232,Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.,male gamete generation,biological_process
77543,GO:0048235,The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.,pollen sperm cell differentiation,biological_process
77544,GO:0048236,The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.,plant-type sporogenesis,biological_process
77545,GO:0048237,The volume enclosed by the membranes of the rough endoplasmic reticulum.,rough endoplasmic reticulum lumen,cellular_component
77546,GO:0048238,The volume enclosed by the membranes of the smooth endoplasmic reticulum.,smooth endoplasmic reticulum lumen,cellular_component
77547,GO:0048239,"Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.",negative regulation of DNA recombination at telomere,biological_process
77548,GO:0048240,"A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.",sperm capacitation,biological_process
77549,GO:0048242,"The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.",epinephrine secretion,biological_process
77550,GO:0048243,The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.,norepinephrine secretion,biological_process
77551,GO:0048244,Catalysis of the reaction: 2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.,phytanoyl-CoA dioxygenase activity,molecular_function
77552,GO:0048245,The movement of an eosinophil in response to an external stimulus.,eosinophil chemotaxis,biological_process
77553,GO:0048246,The movement of a macrophage in response to an external stimulus.,macrophage chemotaxis,biological_process
77554,GO:0048247,The directed movement of a lymphocyte in response to an external stimulus.,lymphocyte chemotaxis,biological_process
77555,GO:0048248,Binding to a CXCR3 chemokine receptor.,CXCR3 chemokine receptor binding,molecular_function
77556,GO:0048249,Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity phosphate transmembrane transporter activity,molecular_function
77557,GO:0048250,The process in which iron is transported from the cytosol into the mitochondrial matrix.,iron import into the mitochondrion,biological_process
77558,GO:0048251,Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.,elastic fiber assembly,biological_process
77559,GO:0048252,"The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.",lauric acid metabolic process,biological_process
77560,GO:0048254,"Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.",snoRNA localization,biological_process
77561,GO:0048255,"Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.",mRNA stabilization,biological_process
77562,GO:0048256,"Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.",flap endonuclease activity,molecular_function
77563,GO:0048257,"Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.",3'-flap endonuclease activity,molecular_function
77564,GO:0048259,"Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.",regulation of receptor-mediated endocytosis,biological_process
77565,GO:0048260,"Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.",positive regulation of receptor-mediated endocytosis,biological_process
77566,GO:0048261,"Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.",negative regulation of receptor-mediated endocytosis,biological_process
77567,GO:0048262,"Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.",determination of dorsal/ventral asymmetry,biological_process
77568,GO:0048263,Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,determination of dorsal identity,biological_process
77569,GO:0048264,The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,determination of ventral identity,biological_process
77570,GO:0048265,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.",response to pain,biological_process
77571,GO:0048266,"Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.",behavioral response to pain,biological_process
77572,GO:0048268,The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.,clathrin coat assembly,biological_process
77573,GO:0048269,"A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.",methionine adenosyltransferase complex,cellular_component
77574,GO:0048270,Binds to and modulates the activity of methionine adenosyltransferase.,methionine adenosyltransferase regulator activity,molecular_function
77575,GO:0048273,"Binding to mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.",mitogen-activated protein kinase p38 binding,molecular_function
77576,GO:0048279,The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.,vesicle fusion with endoplasmic reticulum,biological_process
77577,GO:0048280,The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.,vesicle fusion with Golgi apparatus,biological_process
77578,GO:0048281,The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.,inflorescence morphogenesis,biological_process
77579,GO:0048282,The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.,determinate inflorescence morphogenesis,biological_process
77580,GO:0048283,The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.,indeterminate inflorescence morphogenesis,biological_process
77581,GO:0048284,The creation of a single organelle from two or more organelles.,organelle fusion,biological_process
77582,GO:0048285,The creation of two or more organelles by division of one organelle.,organelle fission,biological_process
77583,GO:0048286,"The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.",lung alveolus development,biological_process
77584,GO:0048288,The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.,nuclear membrane fusion involved in karyogamy,biological_process
77585,GO:0048289,"The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.",isotype switching to IgE isotypes,biological_process
77586,GO:0048290,"The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.",isotype switching to IgA isotypes,biological_process
77587,GO:0048291,"The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.",isotype switching to IgG isotypes,biological_process
77588,GO:0048292,"The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.",isotype switching to IgD isotypes,biological_process
77589,GO:0048293,"Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.",regulation of isotype switching to IgE isotypes,biological_process
77590,GO:0048294,"Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.",negative regulation of isotype switching to IgE isotypes,biological_process
77591,GO:0048295,"Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.",positive regulation of isotype switching to IgE isotypes,biological_process
77592,GO:0048296,"Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.",regulation of isotype switching to IgA isotypes,biological_process
77593,GO:0048297,"Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.",negative regulation of isotype switching to IgA isotypes,biological_process
77594,GO:0048298,"Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.",positive regulation of isotype switching to IgA isotypes,biological_process
77595,GO:0048299,"Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.",regulation of isotype switching to IgD isotypes,biological_process
77596,GO:0048300,"Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.",negative regulation of isotype switching to IgD isotypes,biological_process
77597,GO:0048301,"Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.",positive regulation of isotype switching to IgD isotypes,biological_process
77598,GO:0048302,"Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.",regulation of isotype switching to IgG isotypes,biological_process
77599,GO:0048303,"Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.",negative regulation of isotype switching to IgG isotypes,biological_process
77600,GO:0048304,"Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.",positive regulation of isotype switching to IgG isotypes,biological_process
77601,GO:0048306,Binding to a protein or protein complex in the presence of calcium.,calcium-dependent protein binding,molecular_function
77602,GO:0048307,Catalysis of the reaction: 2 H2O + NH4+ + 6 oxidized [2Fe-2S]-[ferredoxin] = 8 H+ + nitrite + 6 reduced [2Fe-2S]-[ferredoxin].,ferredoxin-nitrite reductase activity,molecular_function
77603,GO:0048308,The partitioning of organelles between daughter cells at cell division.,organelle inheritance,biological_process
77604,GO:0048309,The partitioning of endoplasmic reticulum between daughter cells at cell division.,endoplasmic reticulum inheritance,biological_process
77605,GO:0048311,Any process that establishes the spatial arrangement of mitochondria between and within cells.,mitochondrion distribution,biological_process
77606,GO:0048312,Any process that establishes the spatial arrangement of mitochondria within the cell.,intracellular distribution of mitochondria,biological_process
77607,GO:0048313,The partitioning of Golgi apparatus between daughter cells at cell division.,Golgi inheritance,biological_process
77608,GO:0048314,The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.,embryo sac morphogenesis,biological_process
77609,GO:0048315,"The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.",conidium formation,biological_process
77610,GO:0048316,"The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.",seed development,biological_process
77611,GO:0048317,The process in which the anatomical structures of the seed are generated and organized.,seed morphogenesis,biological_process
77612,GO:0048318,"The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.",axial mesoderm development,biological_process
77613,GO:0048319,The process in which the anatomical structures of the axial mesoderm are generated and organized.,axial mesoderm morphogenesis,biological_process
77614,GO:0048320,The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.,axial mesoderm formation,biological_process
77615,GO:0048321,The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.,axial mesodermal cell differentiation,biological_process
77616,GO:0048322,The process in which a cell becomes committed to become an axial mesoderm cell.,axial mesodermal cell fate commitment,biological_process
77617,GO:0048323,"The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",axial mesodermal cell fate determination,biological_process
77618,GO:0048324,"Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.",regulation of axial mesodermal cell fate determination,biological_process
77619,GO:0048325,"Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.",negative regulation of axial mesodermal cell fate determination,biological_process
77620,GO:0048326,"Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.",positive regulation of axial mesodermal cell fate determination,biological_process
77621,GO:0048327,"The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",axial mesodermal cell fate specification,biological_process
77622,GO:0048328,"Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.",regulation of axial mesodermal cell fate specification,biological_process
77623,GO:0048329,"Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.",negative regulation of axial mesodermal cell fate specification,biological_process
77624,GO:0048330,"Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.",positive regulation of axial mesodermal cell fate specification,biological_process
77625,GO:0048331,The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.,axial mesoderm structural organization,biological_process
77626,GO:0048332,The process in which the anatomical structures of the mesoderm are generated and organized.,mesoderm morphogenesis,biological_process
77627,GO:0048333,The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.,mesodermal cell differentiation,biological_process
77628,GO:0048334,"Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.",regulation of mesodermal cell fate determination,biological_process
77629,GO:0048335,"Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.",negative regulation of mesodermal cell fate determination,biological_process
77630,GO:0048336,"Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.",positive regulation of mesodermal cell fate determination,biological_process
77631,GO:0048337,"Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.",positive regulation of mesodermal cell fate specification,biological_process
77632,GO:0048338,The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.,mesoderm structural organization,biological_process
77633,GO:0048339,"The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.",paraxial mesoderm development,biological_process
77634,GO:0048340,The process in which the anatomical structures of the paraxial mesoderm are generated and organized.,paraxial mesoderm morphogenesis,biological_process
77635,GO:0048341,The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.,paraxial mesoderm formation,biological_process
77636,GO:0048342,The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.,paraxial mesodermal cell differentiation,biological_process
77637,GO:0048343,The process in which a cell becomes committed to become a paraxial mesoderm cell.,paraxial mesodermal cell fate commitment,biological_process
77638,GO:0048344,"The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",paraxial mesodermal cell fate determination,biological_process
77639,GO:0048345,"Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.",regulation of paraxial mesodermal cell fate determination,biological_process
77640,GO:0048346,"Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.",positive regulation of paraxial mesodermal cell fate determination,biological_process
77641,GO:0048347,"Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.",negative regulation of paraxial mesodermal cell fate determination,biological_process
77642,GO:0048348,"The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",paraxial mesodermal cell fate specification,biological_process
77643,GO:0048349,"Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.",regulation of paraxial mesodermal cell fate specification,biological_process
77644,GO:0048350,"Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.",positive regulation of paraxial mesodermal cell fate specification,biological_process
77645,GO:0048351,"Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.",negative regulation of paraxial mesodermal cell fate specification,biological_process
77646,GO:0048352,The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.,paraxial mesoderm structural organization,biological_process
77647,GO:0048353,Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.,primary endosperm nucleus,cellular_component
77648,GO:0048354,The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.,mucilage biosynthetic process involved in seed coat development,biological_process
77649,GO:0048355,The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.,root cap mucilage biosynthetic process,biological_process
77650,GO:0048356,The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.,root epithelial mucilage biosynthetic process,biological_process
77651,GO:0048357,The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.,pedicel mucilage biosynthetic process,biological_process
77652,GO:0048358,The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.,mucilage pectin biosynthetic process,biological_process
77653,GO:0048363,The chemical reactions and pathways involving the pectin component of mucilage.,mucilage pectin metabolic process,biological_process
77654,GO:0048364,"The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.",root development,biological_process
77655,GO:0048366,"The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.",leaf development,biological_process
77656,GO:0048367,"The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.",shoot system development,biological_process
77657,GO:0048368,"The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.",lateral mesoderm development,biological_process
77658,GO:0048369,The process in which the anatomical structures of the lateral mesoderm are generated and organized.,lateral mesoderm morphogenesis,biological_process
77659,GO:0048370,The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.,lateral mesoderm formation,biological_process
77660,GO:0048371,The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.,lateral mesodermal cell differentiation,biological_process
77661,GO:0048372,The process in which a cell becomes committed to become a lateral mesoderm cell.,lateral mesodermal cell fate commitment,biological_process
77662,GO:0048373,"The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",lateral mesodermal cell fate determination,biological_process
77663,GO:0048374,"Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.",regulation of lateral mesodermal cell fate determination,biological_process
77664,GO:0048375,"Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.",negative regulation of lateral mesodermal cell fate determination,biological_process
77665,GO:0048376,"Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.",positive regulation of lateral mesodermal cell fate determination,biological_process
77666,GO:0048377,"The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",lateral mesodermal cell fate specification,biological_process
77667,GO:0048378,"Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.",regulation of lateral mesodermal cell fate specification,biological_process
77668,GO:0048379,"Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.",positive regulation of lateral mesodermal cell fate specification,biological_process
77669,GO:0048380,"Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.",negative regulation of lateral mesodermal cell fate specification,biological_process
77670,GO:0048381,The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.,lateral mesoderm structural organization,biological_process
77671,GO:0048382,"The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.",mesendoderm development,biological_process
77672,GO:0048383,"The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.",mesectoderm development,biological_process
77673,GO:0048384,"A nuclear receptor-mediated signaling pathway initiated by a retinoic acid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",retinoic acid receptor signaling pathway,biological_process
77674,GO:0048385,"Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.",regulation of retinoic acid receptor signaling pathway,biological_process
77675,GO:0048386,"Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.",positive regulation of retinoic acid receptor signaling pathway,biological_process
77676,GO:0048387,"Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.",negative regulation of retinoic acid receptor signaling pathway,biological_process
77677,GO:0048388,"Any process that reduces the pH of the endosomal lumen, corresponding to an increase in hydrogen ion concentration.",endosomal lumen acidification,biological_process
77678,GO:0048389,"The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.",intermediate mesoderm development,biological_process
77679,GO:0048390,The process in which the anatomical structures of the intermediate mesoderm are generated and organized.,intermediate mesoderm morphogenesis,biological_process
77680,GO:0048391,The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.,intermediate mesoderm formation,biological_process
77681,GO:0048392,The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.,intermediate mesodermal cell differentiation,biological_process
77682,GO:0048393,The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.,intermediate mesodermal cell fate commitment,biological_process
77683,GO:0048394,"The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.",intermediate mesodermal cell fate determination,biological_process
77684,GO:0048395,"Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.",regulation of intermediate mesodermal cell fate determination,biological_process
77685,GO:0048396,"Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.",negative regulation of intermediate mesodermal cell fate determination,biological_process
77686,GO:0048397,"Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.",positive regulation of intermediate mesodermal cell fate determination,biological_process
77687,GO:0048398,"The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",intermediate mesodermal cell fate specification,biological_process
77688,GO:0048399,"Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.",regulation of intermediate mesodermal cell fate specification,biological_process
77689,GO:0048400,"Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.",positive regulation of intermediate mesodermal cell fate specification,biological_process
77690,GO:0048401,"Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.",negative regulation of intermediate mesodermal cell fate specification,biological_process
77691,GO:0048402,The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.,intermediate mesoderm structural organization,biological_process
77692,GO:0048403,Binding to brain-derived neurotrophic factor.,brain-derived neurotrophic factor binding,molecular_function
77693,GO:0048406,Binding to nerve growth factor (NGF).,nerve growth factor binding,molecular_function
77694,GO:0048407,Binding to platelet-derived growth factor.,platelet-derived growth factor binding,molecular_function
77695,GO:0048408,Binding to epidermal growth factor.,epidermal growth factor binding,molecular_function
77696,GO:0048437,"The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.",floral organ development,biological_process
77697,GO:0048438,"The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.",floral whorl development,biological_process
77698,GO:0048439,The process in which the anatomical structures of the flower are generated and organized.,flower morphogenesis,biological_process
77699,GO:0048440,"The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.",carpel development,biological_process
77700,GO:0048441,"The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.",petal development,biological_process
77701,GO:0048442,"The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.",sepal development,biological_process
77702,GO:0048443,"The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.",stamen development,biological_process
77703,GO:0048444,The process in which the anatomical structures of the floral organ are generated and organized.,floral organ morphogenesis,biological_process
77704,GO:0048445,The process in which the anatomical structures of the carpel are generated and organized.,carpel morphogenesis,biological_process
77705,GO:0048446,The process in which the anatomical structures of the petal are generated and organized.,petal morphogenesis,biological_process
77706,GO:0048447,The process in which the anatomical structures of the sepal are generated and organized.,sepal morphogenesis,biological_process
77707,GO:0048448,The process in which the anatomical structures of the stamen are generated and organized.,stamen morphogenesis,biological_process
77708,GO:0048449,The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.,floral organ formation,biological_process
77709,GO:0048450,The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.,floral organ structural organization,biological_process
77710,GO:0048451,The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.,petal formation,biological_process
77711,GO:0048452,The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.,petal structural organization,biological_process
77712,GO:0048453,The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.,sepal formation,biological_process
77713,GO:0048454,The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.,sepal structural organization,biological_process
77714,GO:0048455,The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.,stamen formation,biological_process
77715,GO:0048456,The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.,stamen structural organization,biological_process
77716,GO:0048457,The process in which the anatomical structures of the floral whorl are generated and organized.,floral whorl morphogenesis,biological_process
77717,GO:0048458,The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.,floral whorl formation,biological_process
77718,GO:0048459,The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.,floral whorl structural organization,biological_process
77719,GO:0048460,The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.,flower formation,biological_process
77720,GO:0048461,The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.,flower structural organization,biological_process
77721,GO:0048462,The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.,carpel formation,biological_process
77722,GO:0048463,The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.,carpel structural organization,biological_process
77723,GO:0048464,"The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.",flower calyx development,biological_process
77724,GO:0048465,"The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.",corolla development,biological_process
77725,GO:0048466,"The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.",androecium development,biological_process
77726,GO:0048467,"The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.",gynoecium development,biological_process
77727,GO:0048468,The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.,cell development,biological_process
77728,GO:0048469,"The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state.",cell maturation,biological_process
77729,GO:0048471,"Cytoplasm situated near, or occurring around, the nucleus.",perinuclear region of cytoplasm,cellular_component
77730,GO:0048472,Catalysis of the reaction: O-phospho-L-threonine + H+ = (R)-1-aminopropan-2-yl phosphate + CO2.,threonine-phosphate decarboxylase activity,molecular_function
77731,GO:0048473,"The process in which D-methionine is transported across a lipid bilayer, from one side of a membrane to the other.",D-methionine transmembrane transport,biological_process
77732,GO:0048475,"A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.",coated membrane,cellular_component
77733,GO:0048476,An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.,Holliday junction resolvase complex,cellular_component
77734,GO:0048477,The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.,oogenesis,biological_process
77735,GO:0048479,"The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.",style development,biological_process
77736,GO:0048480,"The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.",stigma development,biological_process
77737,GO:0048481,"The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.",plant ovule development,biological_process
77738,GO:0048482,"The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.",plant ovule morphogenesis,biological_process
77739,GO:0048483,"The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.",autonomic nervous system development,biological_process
77740,GO:0048484,"The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can auto...",enteric nervous system development,biological_process
77741,GO:0048485,"The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and ...",sympathetic nervous system development,biological_process
77742,GO:0048486,"The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors...",parasympathetic nervous system development,biological_process
77743,GO:0048487,Binding to the microtubule constituent protein beta-tubulin.,beta-tubulin binding,molecular_function
77744,GO:0048488,"A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.",synaptic vesicle endocytosis,biological_process
77745,GO:0048489,The directed movement of synaptic vesicles.,synaptic vesicle transport,biological_process
77746,GO:0048490,The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.,anterograde synaptic vesicle transport,biological_process
77747,GO:0048491,The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body.,retrograde synaptic vesicle transport,biological_process
77748,GO:0048492,"A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.",ribulose bisphosphate carboxylase complex,cellular_component
77749,GO:0048493,"A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.",plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex,cellular_component
77750,GO:0048494,"A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.",chromatophore ribulose bisphosphate carboxylase complex,cellular_component
77751,GO:0048495,"Binding to Roundabout (ROBO) receptor, a transmembrane receptor.",Roundabout binding,molecular_function
77752,GO:0048496,The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,maintenance of animal organ identity,biological_process
77753,GO:0048497,The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,maintenance of floral organ identity,biological_process
77754,GO:0048498,The process that determines the orientation of petals with reference to the central axis.,establishment of petal orientation,biological_process
77755,GO:0048499,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.",synaptic vesicle membrane organization,biological_process
77756,GO:0048500,A complex of protein and RNA which facilitates translocation of proteins across membranes.,signal recognition particle,cellular_component
77757,GO:0048501,A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.,"signal recognition particle, plasma membrane targeting",cellular_component
77758,GO:0048502,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H+ + phosphate + thiamine(in).,ABC-type thiamine transporter activity,molecular_function
77759,GO:0048504,"Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development.",regulation of timing of animal organ formation,biological_process
77760,GO:0048505,"The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.",regulation of timing of cell differentiation,biological_process
77761,GO:0048506,"Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.",regulation of timing of meristematic phase transition,biological_process
77762,GO:0048507,"The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.",meristem development,biological_process
77763,GO:0048508,"The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.",embryonic meristem development,biological_process
77764,GO:0048509,"Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.",regulation of meristem development,biological_process
77765,GO:0048510,"The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.",regulation of timing of transition from vegetative to reproductive phase,biological_process
77766,GO:0048511,Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.,rhythmic process,biological_process
77767,GO:0048512,The specific behavior of an organism that recurs with a regularity of approximately 24 hours.,circadian behavior,biological_process
77768,GO:0048513,"Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",animal organ development,biological_process
77769,GO:0048514,The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.,blood vessel morphogenesis,biological_process
77770,GO:0048515,"The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",spermatid differentiation,biological_process
77771,GO:0048518,"Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.",positive regulation of biological process,biological_process
77772,GO:0048519,"Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.",negative regulation of biological process,biological_process
77773,GO:0048520,"Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.",positive regulation of behavior,biological_process
77774,GO:0048521,"Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.",negative regulation of behavior,biological_process
77775,GO:0048522,"Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",positive regulation of cellular process,biological_process
77776,GO:0048523,"Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",negative regulation of cellular process,biological_process
77777,GO:0048524,"Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.",positive regulation of viral process,biological_process
77778,GO:0048525,"Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.",negative regulation of viral process,biological_process
77779,GO:0048526,"The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.",imaginal disc-derived wing expansion,biological_process
77780,GO:0048527,"The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.",lateral root development,biological_process
77781,GO:0048528,"The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.",post-embryonic root development,biological_process
77782,GO:0048529,Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.,magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity,molecular_function
77783,GO:0048530,The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.,fruit morphogenesis,biological_process
77784,GO:0048531,"Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.","beta-1,3-galactosyltransferase activity",molecular_function
77785,GO:0048532,"The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",anatomical structure arrangement,biological_process
77786,GO:0048533,"The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.",sporocyte differentiation,biological_process
77787,GO:0048534,"The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.",hematopoietic or lymphoid organ development,biological_process
77788,GO:0048535,"The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.",lymph node development,biological_process
77789,GO:0048536,"The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.",spleen development,biological_process
77790,GO:0048537,"The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.",mucosa-associated lymphoid tissue development,biological_process
77791,GO:0048538,"The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.",thymus development,biological_process
77792,GO:0048539,"The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.",bone marrow development,biological_process
77793,GO:0048540,"The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.",bursa of Fabricius development,biological_process
77794,GO:0048541,"The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.",Peyer's patch development,biological_process
77795,GO:0048542,"The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.",lymph gland development,biological_process
77796,GO:0048543,"The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.",phytochrome chromophore biosynthetic process,biological_process
77797,GO:0048544,A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma.,recognition of pollen,biological_process
77798,GO:0048545,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.",response to steroid hormone,biological_process
77799,GO:0048546,The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.,digestive tract morphogenesis,biological_process
77800,GO:0048548,"Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.",regulation of pinocytosis,biological_process
77801,GO:0048549,"Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.",positive regulation of pinocytosis,biological_process
77802,GO:0048550,"Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.",negative regulation of pinocytosis,biological_process
77803,GO:0048555,"The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.",generative cell nucleus,cellular_component
77804,GO:0048556,"The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.",microsporocyte nucleus,cellular_component
77805,GO:0048557,The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.,embryonic digestive tract morphogenesis,biological_process
77806,GO:0048559,The process that determines the orientation of the floral organs with reference to the central axis of the flower.,establishment of floral organ orientation,biological_process
77807,GO:0048560,The process that determines the orientation of an anatomical structure with reference to an axis.,establishment of anatomical structure orientation,biological_process
77808,GO:0048561,The process that determines the orientation of an animal organ or tissue with reference to an axis.,establishment of animal organ orientation,biological_process
77809,GO:0048562,"Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",embryonic organ morphogenesis,biological_process
77810,GO:0048564,"The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.",photosystem I assembly,biological_process
77811,GO:0048565,"The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.",digestive tract development,biological_process
77812,GO:0048566,"The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.",embryonic digestive tract development,biological_process
77813,GO:0048567,The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.,ectodermal digestive tract morphogenesis,biological_process
77814,GO:0048568,"Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",embryonic organ development,biological_process
77815,GO:0048570,"The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.",notochord morphogenesis,biological_process
77816,GO:0048571,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of th...",long-day photoperiodism,biological_process
77817,GO:0048572,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds t...",short-day photoperiodism,biological_process
77818,GO:0048573,"A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species.","photoperiodism, flowering",biological_process
77819,GO:0048574,"A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.","long-day photoperiodism, flowering",biological_process
77820,GO:0048575,"A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.","short-day photoperiodism, flowering",biological_process
77821,GO:0048576,"Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","positive regulation of short-day photoperiodism, flowering",biological_process
77822,GO:0048577,"Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","negative regulation of short-day photoperiodism, flowering",biological_process
77823,GO:0048578,"Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","positive regulation of long-day photoperiodism, flowering",biological_process
77824,GO:0048579,"Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","negative regulation of long-day photoperiodism, flowering",biological_process
77825,GO:0048580,"Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.",regulation of post-embryonic development,biological_process
77826,GO:0048581,"Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.",negative regulation of post-embryonic development,biological_process
77827,GO:0048582,"Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.",positive regulation of post-embryonic development,biological_process
77828,GO:0048583,"Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.",regulation of response to stimulus,biological_process
77829,GO:0048584,"Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.",positive regulation of response to stimulus,biological_process
77830,GO:0048585,"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.",negative regulation of response to stimulus,biological_process
77831,GO:0048586,"Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","regulation of long-day photoperiodism, flowering",biological_process
77832,GO:0048587,"Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","regulation of short-day photoperiodism, flowering",biological_process
77833,GO:0048588,"The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.",developmental cell growth,biological_process
77834,GO:0048589,"The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.",developmental growth,biological_process
77835,GO:0048592,The process in which the anatomical structures of the eye are generated and organized.,eye morphogenesis,biological_process
77836,GO:0048593,"The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.",camera-type eye morphogenesis,biological_process
77837,GO:0048596,The process in which the anatomical structures of the eye are generated and organized during embryonic development.,embryonic camera-type eye morphogenesis,biological_process
77838,GO:0048597,The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.,post-embryonic camera-type eye morphogenesis,biological_process
77839,GO:0048598,"The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.",embryonic morphogenesis,biological_process
77840,GO:0048599,"The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",oocyte development,biological_process
77841,GO:0048600,The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.,oocyte fate commitment,biological_process
77842,GO:0048601,The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.,oocyte morphogenesis,biological_process
77843,GO:0048608,"The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.",reproductive structure development,biological_process
77844,GO:0048609,"The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.",multicellular organismal reproductive process,biological_process
77845,GO:0048611,"The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.",embryonic ectodermal digestive tract development,biological_process
77846,GO:0048612,"The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.",post-embryonic ectodermal digestive tract development,biological_process
77847,GO:0048613,"The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.",embryonic ectodermal digestive tract morphogenesis,biological_process
77848,GO:0048614,"The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.",post-embryonic ectodermal digestive tract morphogenesis,biological_process
77849,GO:0048615,"The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.",embryonic anterior midgut (ectodermal) morphogenesis,biological_process
77850,GO:0048616,"The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.",post-embryonic anterior midgut (ectodermal) morphogenesis,biological_process
77851,GO:0048617,"The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.",embryonic foregut morphogenesis,biological_process
77852,GO:0048618,"The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.",post-embryonic foregut morphogenesis,biological_process
77853,GO:0048619,"The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.",embryonic hindgut morphogenesis,biological_process
77854,GO:0048620,"The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.",post-embryonic hindgut morphogenesis,biological_process
77855,GO:0048621,"The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.",post-embryonic digestive tract morphogenesis,biological_process
77856,GO:0048623,The process in which a seed germinates before being shed from the parent plant.,seed germination on parent plant,biological_process
77857,GO:0048624,"The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.",plantlet formation on parent plant,biological_process
77858,GO:0048625,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fate commitment,biological_process
77859,GO:0048626,"The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast fate specification,biological_process
77860,GO:0048627,"The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast development,biological_process
77861,GO:0048628,"A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast maturation,biological_process
77862,GO:0048629,The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.,trichome patterning,biological_process
77863,GO:0048630,The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.,skeletal muscle tissue growth,biological_process
77864,GO:0048631,"Any process that modulates the frequency, rate or extent of skeletal muscle growth.",regulation of skeletal muscle tissue growth,biological_process
77865,GO:0048632,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.",negative regulation of skeletal muscle tissue growth,biological_process
77866,GO:0048633,"Any process that activates, maintains or increases the rate of skeletal muscle growth.",positive regulation of skeletal muscle tissue growth,biological_process
77867,GO:0048634,"Any process that modulates the frequency, rate or extent of muscle development.",regulation of muscle organ development,biological_process
77868,GO:0048635,"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.",negative regulation of muscle organ development,biological_process
77869,GO:0048636,"Any process that activates, maintains or increases the rate of muscle development.",positive regulation of muscle organ development,biological_process
77870,GO:0048638,"Any process that modulates the frequency, rate or extent of developmental growth.",regulation of developmental growth,biological_process
77871,GO:0048639,"Any process that activates, maintains or increases the rate of developmental growth.",positive regulation of developmental growth,biological_process
77872,GO:0048640,"Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.",negative regulation of developmental growth,biological_process
77873,GO:0048641,"Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.",regulation of skeletal muscle tissue development,biological_process
77874,GO:0048642,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.",negative regulation of skeletal muscle tissue development,biological_process
77875,GO:0048643,"Any process that activates, maintains or increases the rate of skeletal muscle tissue development.",positive regulation of skeletal muscle tissue development,biological_process
77876,GO:0048644,The process in which the anatomical structures of muscle are generated and organized.,muscle organ morphogenesis,biological_process
77877,GO:0048645,"The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which ...",animal organ formation,biological_process
77878,GO:0048646,"The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",anatomical structure formation involved in morphogenesis,biological_process
77879,GO:0048647,The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.,polyphenic determination,biological_process
77880,GO:0048648,"The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.",caste determination,biological_process
77881,GO:0048649,"The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.","caste determination, influence by genetic factors",biological_process
77882,GO:0048650,"The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.","caste determination, influence by environmental factors",biological_process
77883,GO:0048651,The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.,"polyphenic determination, influence by environmental factors",biological_process
77884,GO:0048652,The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.,"polyphenic determination, influence by genetic factors",biological_process
77885,GO:0048653,"The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.",anther development,biological_process
77886,GO:0048654,The process in which the anatomical structures of the anther are generated and organized.,anther morphogenesis,biological_process
77887,GO:0048655,The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.,anther wall tapetum morphogenesis,biological_process
77888,GO:0048656,The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.,anther wall tapetum formation,biological_process
77889,GO:0048657,The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.,anther wall tapetum cell differentiation,biological_process
77890,GO:0048658,"The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.",anther wall tapetum development,biological_process
77891,GO:0048659,"The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.",smooth muscle cell proliferation,biological_process
77892,GO:0048660,"Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.",regulation of smooth muscle cell proliferation,biological_process
77893,GO:0048661,Any process that activates or increases the rate or extent of smooth muscle cell proliferation.,positive regulation of smooth muscle cell proliferation,biological_process
77894,GO:0048662,"Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.",negative regulation of smooth muscle cell proliferation,biological_process
77895,GO:0048663,The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.,neuron fate commitment,biological_process
77896,GO:0048664,"The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.",neuron fate determination,biological_process
77897,GO:0048665,"The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",neuron fate specification,biological_process
77898,GO:0048666,"The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",neuron development,biological_process
77899,GO:0048667,The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.,cell morphogenesis involved in neuron differentiation,biological_process
77900,GO:0048668,The process in which outgrowths develop from the shafts of existing axons.,collateral sprouting,biological_process
77901,GO:0048669,The process in which outgrowths develop from the axons of intact undamaged neurons.,collateral sprouting in absence of injury,biological_process
77902,GO:0048670,"Any process that modulates the frequency, rate or extent of collateral sprouting.",regulation of collateral sprouting,biological_process
77903,GO:0048671,"Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.",negative regulation of collateral sprouting,biological_process
77904,GO:0048672,"Any process that activates or increases the frequency, rate or extent of collateral sprouting.",positive regulation of collateral sprouting,biological_process
77905,GO:0048673,"The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.",collateral sprouting of intact axon in response to injury,biological_process
77906,GO:0048674,"The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.",collateral sprouting of injured axon,biological_process
77907,GO:0048675,Long distance growth of a single axon process involved in cellular development.,axon extension,biological_process
77908,GO:0048677,Long distance growth of a single axon process involved in regeneration of the neuron.,axon extension involved in regeneration,biological_process
77909,GO:0048678,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.",response to axon injury,biological_process
77910,GO:0048679,"Any process that modulates the frequency, rate or extent of axon regeneration.",regulation of axon regeneration,biological_process
77911,GO:0048680,"Any process that activates, maintains or increases the rate of axon regeneration.",positive regulation of axon regeneration,biological_process
77912,GO:0048681,"Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.",negative regulation of axon regeneration,biological_process
77913,GO:0048682,The process involved in sprouting of an injured axon.,sprouting of injured axon,biological_process
77914,GO:0048683,"Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.",regulation of collateral sprouting of intact axon in response to injury,biological_process
77915,GO:0048684,"Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.",positive regulation of collateral sprouting of intact axon in response to injury,biological_process
77916,GO:0048685,"Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.",negative regulation of collateral sprouting of intact axon in response to injury,biological_process
77917,GO:0048686,"Any process that modulates the frequency, rate or extent of sprouting of an injured axon.",regulation of sprouting of injured axon,biological_process
77918,GO:0048687,"Any process that activates, maintains or increases the rate of sprouting of an injured axon.",positive regulation of sprouting of injured axon,biological_process
77919,GO:0048688,"Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.",negative regulation of sprouting of injured axon,biological_process
77920,GO:0048689,The formation of a growth cone in an injured axon.,formation of growth cone in injured axon,biological_process
77921,GO:0048691,"Any process that activates, maintains or increases the rate of axon extension involved in regeneration.",positive regulation of axon extension involved in regeneration,biological_process
77922,GO:0048692,"Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.",negative regulation of axon extension involved in regeneration,biological_process
77923,GO:0048693,"Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.",regulation of collateral sprouting of injured axon,biological_process
77924,GO:0048694,"Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.",positive regulation of collateral sprouting of injured axon,biological_process
77925,GO:0048695,"Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.",negative regulation of collateral sprouting of injured axon,biological_process
77926,GO:0048696,"Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.",regulation of collateral sprouting in absence of injury,biological_process
77927,GO:0048697,"Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.",positive regulation of collateral sprouting in absence of injury,biological_process
77928,GO:0048698,"Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.",negative regulation of collateral sprouting in absence of injury,biological_process
77929,GO:0048699,The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.,generation of neurons,biological_process
77930,GO:0048700,"The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.",acquisition of desiccation tolerance in seed,biological_process
77931,GO:0048701,The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.,embryonic cranial skeleton morphogenesis,biological_process
77932,GO:0048702,The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.,embryonic neurocranium morphogenesis,biological_process
77933,GO:0048703,The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.,embryonic viscerocranium morphogenesis,biological_process
77934,GO:0048704,The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.,embryonic skeletal system morphogenesis,biological_process
77935,GO:0048705,The process in which the anatomical structures of the skeleton are generated and organized.,skeletal system morphogenesis,biological_process
77936,GO:0048706,"The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.",embryonic skeletal system development,biological_process
77937,GO:0048707,"The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.",instar larval or pupal morphogenesis,biological_process
77938,GO:0048708,The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.,astrocyte differentiation,biological_process
77939,GO:0048709,The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.,oligodendrocyte differentiation,biological_process
77940,GO:0048710,"Any process that modulates the frequency, rate or extent of astrocyte differentiation.",regulation of astrocyte differentiation,biological_process
77941,GO:0048711,"Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.",positive regulation of astrocyte differentiation,biological_process
77942,GO:0048712,"Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.",negative regulation of astrocyte differentiation,biological_process
77943,GO:0048713,"Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.",regulation of oligodendrocyte differentiation,biological_process
77944,GO:0048714,"Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.",positive regulation of oligodendrocyte differentiation,biological_process
77945,GO:0048715,"Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.",negative regulation of oligodendrocyte differentiation,biological_process
77946,GO:0048716,The process in which the anatomical structures of labrum are generated and organized.,labrum morphogenesis,biological_process
77947,GO:0048717,The process in which the anatomical structures of the anterior cibarial plate are generated and organized.,anterior cibarial plate morphogenesis,biological_process
77948,GO:0048718,The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.,cibarial fish-trap bristle morphogenesis,biological_process
77949,GO:0048719,The process in which the anatomical structures of the epistomal sclerite are generated and organized.,epistomal sclerite morphogenesis,biological_process
77950,GO:0048720,The process in which the anatomical structures of the posterior cibarial plate are generated and organized.,posterior cibarial plate morphogenesis,biological_process
77951,GO:0048721,The process in which the anatomical structures of the clypeus are generated and organized.,clypeus morphogenesis,biological_process
77952,GO:0048722,"The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.",anterior cibarial plate development,biological_process
77953,GO:0048723,"The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.",clypeus development,biological_process
77954,GO:0048724,"The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.",epistomal sclerite development,biological_process
77955,GO:0048725,"The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.",cibarial fish-trap bristle development,biological_process
77956,GO:0048726,"The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.",labrum development,biological_process
77957,GO:0048727,"The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.",posterior cibarial plate development,biological_process
77958,GO:0048728,"The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.",proboscis development,biological_process
77959,GO:0048729,The process in which the anatomical structures of a tissue are generated and organized.,tissue morphogenesis,biological_process
77960,GO:0048730,"The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.",epidermis morphogenesis,biological_process
77961,GO:0048731,"The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.",system development,biological_process
77962,GO:0048732,"The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.",gland development,biological_process
77963,GO:0048733,"The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.",sebaceous gland development,biological_process
77964,GO:0048734,The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.,proboscis morphogenesis,biological_process
77965,GO:0048735,The process in which the anatomical structures of a haltere are generated and organized.,haltere morphogenesis,biological_process
77966,GO:0048736,"The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.",appendage development,biological_process
77967,GO:0048737,"The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.",imaginal disc-derived appendage development,biological_process
77968,GO:0048738,"The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.",cardiac muscle tissue development,biological_process
77969,GO:0048741,"The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.",skeletal muscle fiber development,biological_process
77970,GO:0048742,"Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.",regulation of skeletal muscle fiber development,biological_process
77971,GO:0048743,"Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.",positive regulation of skeletal muscle fiber development,biological_process
77972,GO:0048744,"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.",negative regulation of skeletal muscle fiber development,biological_process
77973,GO:0048745,"The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.",smooth muscle tissue development,biological_process
77974,GO:0048749,"The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.",compound eye development,biological_process
77975,GO:0048750,The process in which the anatomical structures of the compound eye corneal lens are generated and organized.,compound eye corneal lens morphogenesis,biological_process
77976,GO:0048752,The process in which the anatomical structures of the semicircular canals are generated and organized.,semicircular canal morphogenesis,biological_process
77977,GO:0048753,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.",pigment granule organization,biological_process
77978,GO:0048754,The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.,branching morphogenesis of an epithelial tube,biological_process
77979,GO:0048755,The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).,branching morphogenesis of a nerve,biological_process
77980,GO:0048756,"The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.",sieve cell differentiation,biological_process
77981,GO:0048757,"Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.",pigment granule maturation,biological_process
77982,GO:0048758,The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.,companion cell differentiation,biological_process
77983,GO:0048759,The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.,xylem vessel member cell differentiation,biological_process
77984,GO:0048760,"The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thi...",plant parenchymal cell differentiation,biological_process
77985,GO:0048761,"The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, a...",collenchyma cell differentiation,biological_process
77986,GO:0048762,The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.,mesenchymal cell differentiation,biological_process
77987,GO:0048763,Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration.,calcium-induced calcium release activity,molecular_function
77988,GO:0048764,"A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.",trichoblast maturation,biological_process
77989,GO:0048765,The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.,root hair cell differentiation,biological_process
77990,GO:0048766,The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.,root hair initiation,biological_process
77991,GO:0048767,The process in which the root hair grows longer.,root hair elongation,biological_process
77992,GO:0048768,Localized growth of a plant root hair tip by extension of the cell wall.,root hair cell tip growth,biological_process
77993,GO:0048769,The process in which sarcomeres are added in series within a fiber.,sarcomerogenesis,biological_process
77994,GO:0048770,"A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.",pigment granule,cellular_component
77995,GO:0048771,"The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.",tissue remodeling,biological_process
77996,GO:0048772,"The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.",leucophore differentiation,biological_process
77997,GO:0048773,The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.,erythrophore differentiation,biological_process
77998,GO:0048774,The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.,cyanophore differentiation,biological_process
77999,GO:0048775,"Any process that modulates the frequency, rate or extent of leucophore differentiation.",regulation of leucophore differentiation,biological_process
78000,GO:0048776,"Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.",negative regulation of leucophore differentiation,biological_process
78001,GO:0048777,"Any process that activates or increases the frequency, rate or extent of leucophore differentiation.",positive regulation of leucophore differentiation,biological_process
78002,GO:0048778,"Any process that modulates the frequency, rate or extent of erythrophore differentiation.",regulation of erythrophore differentiation,biological_process
78003,GO:0048779,"Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.",negative regulation of erythrophore differentiation,biological_process
78004,GO:0048780,"Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.",positive regulation of erythrophore differentiation,biological_process
78005,GO:0048781,"Any process that modulates the frequency, rate or extent of cyanophore differentiation.",regulation of cyanophore differentiation,biological_process
78006,GO:0048782,"Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.",negative regulation of cyanophore differentiation,biological_process
78007,GO:0048783,"Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.",positive regulation of cyanophore differentiation,biological_process
78008,GO:0048785,"The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.",hatching gland development,biological_process
78009,GO:0048786,"A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.",presynaptic active zone,cellular_component
78010,GO:0048787,The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.,presynaptic active zone membrane,cellular_component
78011,GO:0048788,"The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.",cytoskeleton of presynaptic active zone,cellular_component
78012,GO:0048789,"The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.",cytoskeletal matrix organization at active zone,biological_process
78013,GO:0048790,A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.,maintenance of presynaptic active zone structure,biological_process
78014,GO:0048791,"The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.",calcium ion-regulated exocytosis of neurotransmitter,biological_process
78015,GO:0048792,"The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.",spontaneous exocytosis of neurotransmitter,biological_process
78016,GO:0048793,"The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.",pronephros development,biological_process
78017,GO:0048794,"The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.",swim bladder development,biological_process
78018,GO:0048795,"The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.",swim bladder morphogenesis,biological_process
78019,GO:0048796,"A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.",swim bladder maturation,biological_process
78020,GO:0048797,"The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.",swim bladder formation,biological_process
78021,GO:0048798,"The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.",swim bladder inflation,biological_process
78022,GO:0048799,"A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.",animal organ maturation,biological_process
78023,GO:0048800,The process in which the anatomical structures of the antenna are generated and organized.,antennal morphogenesis,biological_process
78024,GO:0048801,The process in which the anatomical structures of the antennal joint are generated and organized.,antennal joint morphogenesis,biological_process
78025,GO:0048802,The process in which the anatomical structures of the dorsal part of the body are generated and organized.,notum morphogenesis,biological_process
78026,GO:0048803,The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.,imaginal disc-derived male genitalia morphogenesis,biological_process
78027,GO:0048804,The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.,imaginal disc-derived female genitalia morphogenesis,biological_process
78028,GO:0048805,The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.,imaginal disc-derived genitalia morphogenesis,biological_process
78029,GO:0048806,"The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.",genitalia development,biological_process
78030,GO:0048807,The process in which the anatomical structures of female genitalia are generated and organized.,female genitalia morphogenesis,biological_process
78031,GO:0048808,The process in which the anatomical structures of male genitalia are generated and organized.,male genitalia morphogenesis,biological_process
78032,GO:0048809,The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.,analia morphogenesis,biological_process
78033,GO:0048810,The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.,female analia morphogenesis,biological_process
78034,GO:0048811,The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.,male analia morphogenesis,biological_process
78035,GO:0048812,"The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.",neuron projection morphogenesis,biological_process
78036,GO:0048813,The process in which the anatomical structures of a dendrite are generated and organized.,dendrite morphogenesis,biological_process
78037,GO:0048814,"Any process that modulates the frequency, rate or extent of dendrite morphogenesis.",regulation of dendrite morphogenesis,biological_process
78038,GO:0048816,The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.,ocellus morphogenesis,biological_process
78039,GO:0048817,"Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.",negative regulation of hair follicle maturation,biological_process
78040,GO:0048818,"Any process that activates or increases the frequency, rate or extent of hair follicle maturation.",positive regulation of hair follicle maturation,biological_process
78041,GO:0048819,"Any process that modulates the frequency, rate or extent of hair follicle maturation.",regulation of hair follicle maturation,biological_process
78042,GO:0048820,"A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.",hair follicle maturation,biological_process
78043,GO:0048821,"The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.",erythrocyte development,biological_process
78044,GO:0048822,"The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",enucleate erythrocyte development,biological_process
78045,GO:0048823,"The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",nucleate erythrocyte development,biological_process
78046,GO:0048824,The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.,pigment cell precursor differentiation,biological_process
78047,GO:0048825,"The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.",cotyledon development,biological_process
78048,GO:0048826,"The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.",cotyledon morphogenesis,biological_process
78049,GO:0048827,"The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.",phyllome development,biological_process
78050,GO:0048829,"The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.",root cap development,biological_process
78051,GO:0048830,"The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.",adventitious root development,biological_process
78052,GO:0048831,"Any process that modulates the frequency, rate or extent of shoot development.",regulation of shoot system development,biological_process
78053,GO:0048832,The regionalization process that modulates the quantity of a particular type of plant organ.,specification of plant organ number,biological_process
78054,GO:0048833,Any process that modulates the number of floral organs formed in a floral whorl.,specification of floral organ number,biological_process
78055,GO:0048834,Any process that modulates the number of petals formed in a flower.,specification of petal number,biological_process
78056,GO:0048837,"The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp.",sorocarp sorus development,biological_process
78057,GO:0048838,The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.,release of seed from dormancy,biological_process
78058,GO:0048839,"The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.",inner ear development,biological_process
78059,GO:0048840,"The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.",otolith development,biological_process
78060,GO:0048841,"Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.",regulation of axon extension involved in axon guidance,biological_process
78061,GO:0048842,"Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.",positive regulation of axon extension involved in axon guidance,biological_process
78062,GO:0048843,"Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.",negative regulation of axon extension involved in axon guidance,biological_process
78063,GO:0048844,The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.,artery morphogenesis,biological_process
78064,GO:0048845,The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.,venous blood vessel morphogenesis,biological_process
78065,GO:0048846,"The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.",axon extension involved in axon guidance,biological_process
78066,GO:0048847,The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.,adenohypophysis formation,biological_process
78067,GO:0048848,The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.,neurohypophysis morphogenesis,biological_process
78068,GO:0048849,The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.,neurohypophysis formation,biological_process
78069,GO:0048850,The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.,hypophysis morphogenesis,biological_process
78070,GO:0048851,The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.,hypophysis formation,biological_process
78071,GO:0048852,"The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.",diencephalon morphogenesis,biological_process
78072,GO:0048853,"The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).",forebrain morphogenesis,biological_process
78073,GO:0048854,"The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).",brain morphogenesis,biological_process
78074,GO:0048855,The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.,adenohypophysis morphogenesis,biological_process
78075,GO:0048856,"The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",anatomical structure development,biological_process
78076,GO:0048857,The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.,neural nucleus development,biological_process
78077,GO:0048858,The process in which the anatomical structures of a cell projection are generated and organized.,cell projection morphogenesis,biological_process
78078,GO:0048859,"The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",formation of anatomical boundary,biological_process
78079,GO:0048860,The process resulting in the physical partitioning and separation of a glioblast into daughter cells.,glioblast division,biological_process
78080,GO:0048861,"The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",leukemia inhibitory factor signaling pathway,biological_process
78081,GO:0048863,The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.,stem cell differentiation,biological_process
78082,GO:0048864,"The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.",stem cell development,biological_process
78083,GO:0048865,The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.,stem cell fate commitment,biological_process
78084,GO:0048866,"The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",stem cell fate specification,biological_process
78085,GO:0048867,"The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.",stem cell fate determination,biological_process
78086,GO:0048868,"The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.",pollen tube development,biological_process
78087,GO:0048869,A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.,cellular developmental process,biological_process
78088,GO:0048870,Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.,cell motility,biological_process
78089,GO:0048871,Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.,multicellular organismal-level homeostasis,biological_process
78090,GO:0048872,Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.,homeostasis of number of cells,biological_process
78091,GO:0048873,Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.,homeostasis of number of cells within a tissue,biological_process
78092,GO:0048874,The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.,host-mediated modulation of intestinal microbiota composition,biological_process
78093,GO:0048877,Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.,homeostasis of number of retina cells,biological_process
78094,GO:0048878,Any biological process involved in the maintenance of an internal steady state of a chemical.,chemical homeostasis,biological_process
78095,GO:0048880,The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.,sensory system development,biological_process
78096,GO:0048881,"The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory l...",mechanosensory lateral line system development,biological_process
78097,GO:0048882,"The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.",lateral line development,biological_process
78098,GO:0048883,"The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.",neuromast primordium migration,biological_process
78099,GO:0048884,"The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.",neuromast development,biological_process
78100,GO:0048885,The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.,neuromast deposition,biological_process
78101,GO:0048886,"The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell ...",neuromast hair cell differentiation,biological_process
78102,GO:0048887,"The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.",cupula development,biological_process
78103,GO:0048888,"The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.",neuromast mantle cell differentiation,biological_process
78104,GO:0048889,The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.,neuromast support cell differentiation,biological_process
78105,GO:0048890,"The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.",lateral line ganglion development,biological_process
78106,GO:0048891,The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.,lateral line ganglion neuron differentiation,biological_process
78107,GO:0048892,"The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.",lateral line nerve development,biological_process
78108,GO:0048893,The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.,afferent axon development in lateral line nerve,biological_process
78109,GO:0048894,The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.,efferent axon development in a lateral line nerve,biological_process
78110,GO:0048895,The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.,lateral line nerve glial cell differentiation,biological_process
78111,GO:0048896,The movement of a glial cell along the axons in a lateral line nerve.,lateral line nerve glial cell migration,biological_process
78112,GO:0048897,The formation of compact myelin sheaths around the axons of a lateral line nerve.,myelination of lateral line nerve axons,biological_process
78113,GO:0048898,"The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just un...",anterior lateral line system development,biological_process
78114,GO:0048899,"The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.",anterior lateral line development,biological_process
78115,GO:0048900,"The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.",anterior lateral line neuromast primordium migration,biological_process
78116,GO:0048901,"The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.",anterior lateral line neuromast development,biological_process
78117,GO:0048902,The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.,anterior lateral line neuromast deposition,biological_process
78118,GO:0048903,The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within eac...,anterior lateral line neuromast hair cell differentiation,biological_process
78119,GO:0048904,"The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is...",anterior lateral line neuromast cupula development,biological_process
78120,GO:0048905,"The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.",anterior lateral line neuromast mantle cell differentiation,biological_process
78121,GO:0048906,The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.,anterior lateral line neuromast support cell differentiation,biological_process
78122,GO:0048907,"The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.",anterior lateral line ganglion development,biological_process
78123,GO:0048908,The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.,anterior lateral line ganglion neuron differentiation,biological_process
78124,GO:0048909,"The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.",anterior lateral line nerve development,biological_process
78125,GO:0048910,The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.,afferent axon development in anterior lateral line nerve,biological_process
78126,GO:0048911,The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.,efferent axon development in anterior lateral line nerve,biological_process
78127,GO:0048912,The movement of a glial cell along the axons in the anterior lateral line nerve.,glial cell migration in anterior lateral line nerve,biological_process
78128,GO:0048913,The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.,anterior lateral line nerve glial cell differentiation,biological_process
78129,GO:0048914,The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.,myelination of anterior lateral line nerve axons,biological_process
78130,GO:0048915,"The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the s...",posterior lateral line system development,biological_process
78131,GO:0048916,"The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.",posterior lateral line development,biological_process
78132,GO:0048917,"The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.",posterior lateral line ganglion development,biological_process
78133,GO:0048918,"The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.",posterior lateral line nerve development,biological_process
78134,GO:0048919,"The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.",posterior lateral line neuromast development,biological_process
78135,GO:0048920,"The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.",posterior lateral line neuromast primordium migration,biological_process
78136,GO:0048921,"The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts i...",posterior lateral line neuromast cupula development,biological_process
78137,GO:0048922,The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.,posterior lateral line neuromast deposition,biological_process
78138,GO:0048923,The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morpholog...,posterior lateral line neuromast hair cell differentiation,biological_process
78139,GO:0048924,"The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the cilia...",posterior lateral line neuromast mantle cell differentiation,biological_process
78140,GO:0048925,"The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.",lateral line system development,biological_process
78141,GO:0048926,"The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.",electrosensory lateral line system development,biological_process
78142,GO:0048927,The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.,posterior lateral line neuromast support cell differentiation,biological_process
78143,GO:0048928,The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.,posterior lateral line ganglion neuron differentiation,biological_process
78144,GO:0048929,The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.,efferent axon development in posterior lateral line nerve,biological_process
78145,GO:0048930,The movement of a glial cell along the axons in the posterior lateral line nerve.,glial cell migration in posterior lateral line nerve,biological_process
78146,GO:0048931,The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.,posterior lateral line nerve glial cell differentiation,biological_process
78147,GO:0048932,The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.,myelination of posterior lateral line nerve axons,biological_process
78148,GO:0048933,The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.,afferent axon development in posterior lateral line nerve,biological_process
78149,GO:0048934,The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.,peripheral nervous system neuron differentiation,biological_process
78150,GO:0048935,"The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.",peripheral nervous system neuron development,biological_process
78151,GO:0048936,Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.,peripheral nervous system neuron axonogenesis,biological_process
78152,GO:0048937,"The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",lateral line nerve glial cell development,biological_process
78153,GO:0048939,"The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",anterior lateral line nerve glial cell development,biological_process
78154,GO:0048940,The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.,anterior lateral line nerve glial cell morphogenesis involved in differentiation,biological_process
78155,GO:0048941,"The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",posterior lateral line nerve glial cell development,biological_process
78156,GO:0048942,The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.,posterior lateral line nerve glial cell morphogenesis involved in differentiation,biological_process
78157,GO:0050000,"Any process in which a chromosome is transported to, or maintained in, a specific location.",chromosome localization,biological_process
78158,GO:0050001,Catalysis of the reaction: D-glutamine + H2O = D-glutamate + NH4+.,D-glutaminase activity,molecular_function
78159,GO:0050002,Catalysis of the reaction: 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline.,D-proline reductase activity,molecular_function
78160,GO:0050003,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.",deoxycytidylate C-methyltransferase activity,molecular_function
78161,GO:0050004,Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.,isoflavone 7-O-glucosyltransferase activity,molecular_function
78162,GO:0050005,Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O.,isohexenylglutaconyl-CoA hydratase activity,molecular_function
78163,GO:0050006,Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.,isomaltulose synthase activity,molecular_function
78164,GO:0050007,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H+ + isonocardicin A.,isonocardicin synthase activity,molecular_function
78165,GO:0050008,Catalysis of the reaction: isopiperitenone = piperitenone.,isopiperitenone delta-isomerase activity,molecular_function
78166,GO:0050009,Catalysis of the reaction: NADP+ + propan-2-ol = acetone + H+ + NADPH.,isopropanol dehydrogenase (NADP+) activity,molecular_function
78167,GO:0050010,Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.,isovitexin beta-glucosyltransferase activity,molecular_function
78168,GO:0050011,Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.,itaconyl-CoA hydratase activity,molecular_function
78169,GO:0050012,"Catalysis of the reaction: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H+.",juglone 3-hydroxylase activity,molecular_function
78170,GO:0050013,Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.,2-dehydropantoate aldolase activity,molecular_function
78171,GO:0050014,Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.,ketotetrose-phosphate aldolase activity,molecular_function
78172,GO:0050015,Catalysis of the reaction: kievitone hydrate = H2O + H+ + kievitone.,kievitone hydratase activity,molecular_function
78173,GO:0050016,"Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.","kynurenine 7,8-hydroxylase activity",molecular_function
78174,GO:0050017,Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.,L-3-cyanoalanine synthase activity,molecular_function
78175,GO:0050018,Catalysis of the reaction: an L-alpha-amino acid +NAD(P)+ + H2O = a 2-oxocarboxylate + NH4+ + NAD(P)H + H+.,amino-acid dehydrogenase [NAD(P)+] activity,molecular_function
78176,GO:0050019,Catalysis of the reaction: L-arabinitol + NAD+ = L-xylulose + H+ + NADH.,L-arabinitol 4-dehydrogenase activity,molecular_function
78177,GO:0050020,Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O.,L-arabinonate dehydratase activity,molecular_function
78178,GO:0050021,"Catalysis of the reaction: L-arabinono-1,4-lactone + H2O = L-arabinonate + H+.",L-arabinonolactonase activity,molecular_function
78179,GO:0050022,"Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.",L-arabinose 1-dehydrogenase (NAD+) activity,molecular_function
78180,GO:0050023,Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O.,L-fuconate dehydratase activity,molecular_function
78181,GO:0050024,"Catalysis of the reaction: L-galactono-1,4-lactone + O2 = L-ascorbate + H2O2 + H+.",L-galactonolactone oxidase activity,molecular_function
78182,GO:0050025,Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + H2O2 + NH4+.,L-glutamate oxidase activity,molecular_function
78183,GO:0050026,Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.,L-glycol dehydrogenase activity,molecular_function
78184,GO:0050028,Catalysis of the reaction: L-2-aminohexano-6-lactam + H2O = L-lysine.,L-lysine-lactamase activity,molecular_function
78185,GO:0050029,Catalysis of the reaction: H2O + L-lysine + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4+.,L-lysine oxidase activity,molecular_function
78186,GO:0050030,"Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.",L-pipecolate dehydrogenase activity,molecular_function
78187,GO:0050031,"Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.",L-pipecolate oxidase activity,molecular_function
78188,GO:0050032,Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O.,L-rhamnonate dehydratase activity,molecular_function
78189,GO:0050033,"Catalysis of the reaction: L-rhamnono-1,4-lactone + H2O = L-rhamnonate + H+.","L-rhamnono-1,4-lactonase activity",molecular_function
78190,GO:0050034,"Catalysis of the reaction: L-rhamnofuranose + NAD+ = L-rhamnono-1,4-lactone + H+ + NADH.",L-rhamnose 1-dehydrogenase activity,molecular_function
78191,GO:0050035,Catalysis of the reaction: L-sorbose + O2 = 5-dehydro-D-fructose + H2O2.,L-sorbose oxidase activity,molecular_function
78192,GO:0050036,Catalysis of the reaction: L-threonate + NAD+ = 3-dehydro-L-threonate + H+ + NADH.,L-threonate 3-dehydrogenase activity,molecular_function
78193,GO:0050037,"Catalysis of the reaction: L-xylose + NADP+ = H+ + L-xylono-1,4-lactone + NADPH.",L-xylose 1-dehydrogenase activity,molecular_function
78194,GO:0050038,Catalysis of the reaction: NADP+ + xylitol = L-xylulose + H+ + NADPH.,L-xylulose reductase (NADPH) activity,molecular_function
78195,GO:0050039,"Catalysis of the reaction: NADP+ + propane-1,2-diol = (S)-lactaldehyde + H+ + NADPH.",lactaldehyde reductase (NADPH) activity,molecular_function
78196,GO:0050040,Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O.,lactate 2-monooxygenase activity,molecular_function
78197,GO:0050041,Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.,lactate aldolase activity,molecular_function
78198,GO:0050042,Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.,lactate-malate transhydrogenase activity,molecular_function
78199,GO:0050043,Catalysis of the reaction: (S)-lactate = (R)-lactate.,lactate racemase activity,molecular_function
78200,GO:0050044,Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.,galactose-6-phosphate isomerase activity,molecular_function
78201,GO:0050045,Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.,laminaribiose phosphorylase activity,molecular_function
78202,GO:0050046,"Catalysis of the reaction: a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H+ = a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O.",delta7-sterol 5(6)-desaturase activity,molecular_function
78203,GO:0050047,Catalysis of the reaction: L-leucine = (3R)-beta-leucine.,"L-leucine 2,3-aminomutase activity",molecular_function
78204,GO:0050049,Catalysis of the reaction: L-leucine + NAD+ + H2O = 4-methyl-2-oxopentanoate + NH4+ + NADH + H+.,L-leucine dehydrogenase (NAD+) activity,molecular_function
78205,GO:0050050,Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H+.,L-leucine N-acetyltransferase activity,molecular_function
78206,GO:0050051,Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].,leukotriene-B4 20-monooxygenase activity,molecular_function
78207,GO:0050052,Catalysis of the reaction: H+ + leukotriene E(4) + NADPH + O2 = 20-hydroxy-leukotriene E(4) + H2O + NADP+.,leukotriene-E4 20-monooxygenase activity,molecular_function
78208,GO:0050053,"Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).",levansucrase activity,molecular_function
78209,GO:0050054,"Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.",lignostilbene alpha beta-dioxygenase activity,molecular_function
78210,GO:0050055,Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.,limonin-D-ring-lactonase activity,molecular_function
78211,GO:0050056,Catalysis of the reaction: linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + 2 H+ + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].,linalool 8-monooxygenase activity,molecular_function
78212,GO:0050057,Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.,linamarin synthase activity,molecular_function
78213,GO:0050058,"Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.",linoleate isomerase activity,molecular_function
78214,GO:0050059,Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.,lombricine kinase activity,molecular_function
78215,GO:0050060,Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.,long-chain-alcohol dehydrogenase activity,molecular_function
78216,GO:0050061,Catalysis of the reaction: a long-chain fatty aldehyde + H2O + NAD+ = a long-chain fatty acid + 2 H+ + NADH.,long-chain fatty aldehyde dehydrogenase (NAD+) activity,molecular_function
78217,GO:0050062,Catalysis of the reaction: a long-chain fatty aldehyde + CoA + NADP+ = a long-chain fatty acyl-CoA + NADPH.,long-chain-fatty-acyl-CoA reductase (NADP+) activity,molecular_function
78218,GO:0050064,Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.,luteolin 7-O-glucuronosyltransferase activity,molecular_function
78219,GO:0050065,Catalysis of the reaction: L-lysine + pyruvate = (S)-2-amino-6-oxohexanoate + L-alanine.,L-lysine:pyruvate 6-transaminase activity,molecular_function
78220,GO:0050066,"Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.","L-lysine 2,3-aminomutase activity",molecular_function
78221,GO:0050067,Catalysis of the reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O.,L-lysine 2-monooxygenase activity,molecular_function
78222,GO:0050068,Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H+ + phosphate.,lysine carbamoyltransferase activity,molecular_function
78223,GO:0050069,Catalysis of the reaction: L-lysine + NAD+ = delta1-piperideine-2-carboxylate + NH4+ + NADH + H+.,L-lysine dehydrogenase (NAD+) activity,molecular_function
78224,GO:0050070,Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.,lysolecithin acylmutase activity,molecular_function
78225,GO:0050071,"Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-lysyl-tRNA(Lys) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys).",phosphatidylglycerol lysyltransferase activity,molecular_function
78226,GO:0050073,"Catalysis of the reaction: ATP + a macrolide = ADP + 2 H+ + a macrolide-2'-O-phosphate. Substrates include oleandomycin, erythromycin, spiramycin and other macrolide antibiotics.",macrolide 2'-kinase activity,molecular_function
78227,GO:0050074,Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.,malate-CoA ligase activity,molecular_function
78228,GO:0050075,Catalysis of the reaction: (R)-malate = H2O + maleate.,maleate hydratase activity,molecular_function
78229,GO:0050076,Catalysis of the reaction: maleate = fumarate.,maleate isomerase activity,molecular_function
78230,GO:0050077,Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.,maleylpyruvate isomerase activity,molecular_function
78231,GO:0050078,Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.,malonate CoA-transferase activity,molecular_function
78232,GO:0050079,Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.,acetylenecarboxylate hydratase activity,molecular_function
78233,GO:0050080,Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.,malonyl-CoA decarboxylase activity,molecular_function
78234,GO:0050081,Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.,maltose-6'-phosphate glucosidase activity,molecular_function
78235,GO:0050082,Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.,maltose phosphorylase activity,molecular_function
78236,GO:0050083,Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.,malyl-CoA lyase activity,molecular_function
78237,GO:0050084,Catalysis of the reaction: D-mannitol 1-phosphate + H2O = D-mannitol + 2 H+ + phosphate.,mannitol-1-phosphatase activity,molecular_function
78238,GO:0050085,Catalysis of the reaction: D-mannitol + NADP+ = D-fructose + H+ + NADPH.,mannitol 2-dehydrogenase (NADP+) activity,molecular_function
78239,GO:0050086,Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.,mannitol 2-dehydrogenase activity,molecular_function
78240,GO:0050087,Catalysis of the reaction: 2 [Fe(III)cytochrome c] + D-mannitol = 2 [Fe(II)cytochrome c] + D-fructose + 2 H+.,mannitol dehydrogenase (cytochrome) activity,molecular_function
78241,GO:0050088,Catalysis of the reaction: D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + 3 H+ + NADPH.,mannose-6-phosphate 6-reductase activity,molecular_function
78242,GO:0050089,Catalysis of the reaction: D-mannose = D-fructose.,mannose isomerase activity,molecular_function
78243,GO:0050090,Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.,mannuronate reductase activity,molecular_function
78244,GO:0050091,"Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H+ + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+.",melilotate 3-monooxygenase activity,molecular_function
78245,GO:0050092,"Catalysis of the reaction: (2R,3S)-tartrate + NAD+ = dihydroxyfumarate + H+ + NADH.",meso-tartrate dehydrogenase activity,molecular_function
78246,GO:0050093,Catalysis of the reaction: methanol + NAD+ = formaldehyde + H+ + NADH.,methanol dehydrogenase (NAD+) activity,molecular_function
78247,GO:0050094,Catalysis of the reaction: glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine.,L-methionine:glyoxylate transaminase activity,molecular_function
78248,GO:0050095,Catalysis of the reaction: L-methionine + H+ = 3-methylthiopropanamine + CO2.,methionine decarboxylase activity,molecular_function
78249,GO:0050096,Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH4.,methylaspartate ammonia-lyase activity,molecular_function
78250,GO:0050097,Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.,methylaspartate mutase activity,molecular_function
78251,GO:0050098,Catalysis of the reaction: H2O + methylguanidine = methylammonium + urea.,methylguanidinase activity,molecular_function
78252,GO:0050099,Catalysis of the reaction: N-methyl-L-glutamate + A + H2O = L-glutamate + AH(2) + formaldehyde.,methylglutamate dehydrogenase activity,molecular_function
78253,GO:0050100,Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.,methylitaconate delta-isomerase activity,molecular_function
78254,GO:0050101,Catalysis of the reaction: L-mimosine + H2O = 3-hydroxy-4H-pyrid-4-one + L-serine.,mimosinase activity,molecular_function
78255,GO:0050102,"Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.",cellodextrin phosphorylase activity,molecular_function
78256,GO:0050103,"Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).",dextrin dextranase activity,molecular_function
78257,GO:0050104,Catalysis of the reaction: L-gulonate + NAD+ = 3-dehydro-L-gulonate + H+ + NADH.,L-gulonate 3-dehydrogenase activity,molecular_function
78258,GO:0050105,"Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.",L-gulonolactone oxidase activity,molecular_function
78259,GO:0050106,Catalysis of the reaction: H2O + monomethyl sulfate = H+ + methanol + sulfate.,monomethyl-sulfatase activity,molecular_function
78260,GO:0050107,Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.,monoterpenol O-acetyltransferase activity,molecular_function
78261,GO:0050108,"Catalysis of the reaction: (2S,4R)-bornyl diphosphate + H2O = (1R,2S,4R)-borneol + diphosphate.",monoterpenyl-diphosphatase activity,molecular_function
78262,GO:0050109,Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.,morphine 6-dehydrogenase activity,molecular_function
78263,GO:0050111,Catalysis of the reaction: acyl-CoA + 7n H+ + n methylmalonyl-CoA + 2n NADPH = n CO2 + n CoA + n H2O + multi-methyl-branched acyl-CoA + 2n NADP+.,mycocerosate synthase activity,molecular_function
78264,GO:0050112,"Catalysis of the reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + H+ + NADH.",inositol 2-dehydrogenase (NAD+) activity,molecular_function
78265,GO:0050113,Catalysis of the reaction: myo-inositol + O2 = D-glucuronate + H2O + H+.,inositol oxygenase activity,molecular_function
78266,GO:0050114,"Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O.",myo-inosose-2 dehydratase activity,molecular_function
78267,GO:0050115,Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.,myosin-light-chain-phosphatase activity,molecular_function
78268,GO:0050116,"Catalysis of the reaction: N,N-dimethylformamide + H2O = dimethylamine + formate.","N,N-dimethylformamidase activity",molecular_function
78269,GO:0050117,Catalysis of the reaction: N-acetyl-beta-alanine + H2O = beta-alanine + acetate.,N-acetyl-beta-alanine deacetylase activity,molecular_function
78270,GO:0050118,"Catalysis of the reaction: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + acetate.",N-acetyldiaminopimelate deacetylase activity,molecular_function
78271,GO:0050119,Catalysis of the reaction: N-acetyl-D-glucosamine + H2O = D-glucosamine + acetate.,N-acetylglucosamine deacetylase activity,molecular_function
78272,GO:0050120,Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + NAD+ = N-acetyl-D-glucosaminate + 2 H+ + NADH.,N-acetylhexosamine 1-dehydrogenase activity,molecular_function
78273,GO:0050121,Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.,N-acylglucosamine 2-epimerase activity,molecular_function
78274,GO:0050122,Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + O2 = N-acetyl-D-glucosaminate + H2O2 + H+.,N-acylhexosamine oxidase activity,molecular_function
78275,GO:0050123,Catalysis of the reaction: N-acyl-D-mannosamine + NAD+ = N-acyl-D-mannosaminolactone + H+ + NADH.,N-acylmannosamine 1-dehydrogenase activity,molecular_function
78276,GO:0050124,Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.,N-acylneuraminate-9-phosphatase activity,molecular_function
78277,GO:0050125,Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O + H+ = benzyl alcohol + CO2 + glycine.,N-benzyloxycarbonylglycine hydrolase activity,molecular_function
78278,GO:0050126,Catalysis of the reaction: N-carbamoylputrescine + H2O + 2 H+ = CO2 + NH4 + putrescine.,N-carbamoylputrescine amidase activity,molecular_function
78279,GO:0050127,Catalysis of the reaction: N-carbamoylsarcosine + H2O + 2 H+ = CO2 + NH4 + sarcosine.,N-carbamoylsarcosine amidase activity,molecular_function
78280,GO:0050128,Catalysis of the reaction: N-feruloylglycine + H2O = ferulate + glycine.,N-feruloylglycine deacylase activity,molecular_function
78281,GO:0050129,Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.,N-formylglutamate deformylase activity,molecular_function
78282,GO:0050130,Catalysis of the reaction: N-methyl-2-oxoglutaramate + H2O = 2-oxoglutarate + methylammonium.,N-methyl-2-oxoglutaramate hydrolase activity,molecular_function
78283,GO:0050131,Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.,N-methyl-L-amino-acid oxidase activity,molecular_function
78284,GO:0050132,Catalysis of the reaction: N-methyl-L-alanine + NADP+ + H2O = methylamine + pyruvate + NADPH + H+.,N-methyl-L-alanine dehydrogenase activity,molecular_function
78285,GO:0050133,Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.,N6-hydroxylysine O-acetyltransferase activity,molecular_function
78286,GO:0050134,Catalysis of the reaction: N(6)-methyl-L-lysine + H2O + O2 = L-lysine + formaldehyde + H2O2.,N6-methyl-lysine oxidase activity,molecular_function
78287,GO:0050135,Catalysis of the reaction: NADP+ + H2O = ADP-D-ribose 2'-phosphate + nicotinamide + H+.,NADP+ nucleosidase activity,molecular_function
78288,GO:0050136,Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.,NADH dehydrogenase (quinone) (non-electrogenic) activity,molecular_function
78289,GO:0050137,Catalysis of the reaction: H2O2 + H+ + NADPH = 2 H2O + NADP+.,NADPH peroxidase activity,molecular_function
78290,GO:0050138,Catalysis of the reaction: H2O + NADP+ + nicotinate = 6-hydroxynicotinate + H+ + NADPH.,nicotinate dehydrogenase activity,molecular_function
78291,GO:0050139,Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.,nicotinate-N-glucosyltransferase activity,molecular_function
78292,GO:0050140,Catalysis of the reaction: 2 Fe(II)-[cytochrome] + nitrate + 2 H+ = 2 Fe(III)-[cytochrome] + nitrite + H2O.,nitrate reductase (cytochrome) activity,molecular_function
78293,GO:0050142,Catalysis of the reaction: N2 + 4 reduced [flavodoxin] + 16 ATP + 16 H2O = 4 oxidized [flavodoxin] + H2 + 2 NH4+ + 16 ADP + 16 phosphate + 18 H+.,nitrogenase (flavodoxin) activity,molecular_function
78294,GO:0050143,"Catalysis of the reaction: isonocardicin A = nocardicin A. May also catalyse the epimerisation of isonocardicin C, but the in vivo substrate appears to be isonocardicin A.",nocardicin-A epimerase activity,molecular_function
78295,GO:0050144,Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.,nucleoside deoxyribosyltransferase activity,molecular_function
78296,GO:0050145,Catalysis of the reaction: a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.,nucleoside monophosphate kinase activity,molecular_function
78297,GO:0050146,Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.,nucleoside phosphotransferase activity,molecular_function
78298,GO:0050147,Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.,nucleoside ribosyltransferase activity,molecular_function
78299,GO:0050148,Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.,nucleotide diphosphokinase activity,molecular_function
78300,GO:0050149,Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.,o-aminophenol oxidase activity,molecular_function
78301,GO:0050150,"Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = catechol + CO2.",o-pyrocatechuate decarboxylase activity,molecular_function
78302,GO:0050151,Catalysis of the reaction: (R)-10-hydroxystearate = H2O + oleate.,oleate hydratase activity,molecular_function
78303,GO:0050152,"Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH4+. Substrates include 2-oxosuccinamate and 2-oxoglutaramate, which get converted to oxaloacetate and 2-oxoglutarate, respectively.",omega-amidase activity,molecular_function
78304,GO:0050153,Catalysis of the reaction: 10-hydroxydecanoate + NAD+ = 10-oxodecanoate + H+ + NADH.,omega-hydroxydecanoate dehydrogenase activity,molecular_function
78305,GO:0050154,Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H+.,opheline kinase activity,molecular_function
78306,GO:0050156,"Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.",ornithine N-benzoyltransferase activity,molecular_function
78307,GO:0050157,Catalysis of the reaction: L-ornithine = D-ornithine.,ornithine racemase activity,molecular_function
78308,GO:0050158,Catalysis of the reaction: (S)-dihydroorotate + NADP+ = H+ + NADPH + orotate.,dihydroorotate dehydrogenase (NADP+) activity,molecular_function
78309,GO:0050159,Catalysis of the reaction: o-orsellinate + H+ = CO2 + orcinol.,orsellinate decarboxylase activity,molecular_function
78310,GO:0050160,Catalysis of the reaction: H2O + orsellinate depside = 2 o-orsellinate + H+.,orsellinate-depside hydrolase activity,molecular_function
78311,GO:0050161,Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.,succinyl-CoA:oxalate CoA-transferase activity,molecular_function
78312,GO:0050162,Catalysis of the reaction: 2 H+ + O2 + oxalate = 2 CO2 + H2O2.,oxalate oxidase activity,molecular_function
78313,GO:0050163,Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.,oxaloacetate tautomerase activity,molecular_function
78314,GO:0050165,Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.,pantetheine kinase activity,molecular_function
78315,GO:0050166,Catalysis of the reaction: (R)-pantoate + NAD+ = (R)-4-dehydropantoate + H+ + NADH.,pantoate 4-dehydrogenase activity,molecular_function
78316,GO:0050167,Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H+ = (R)-pantetheine + CO2.,pantothenoylcysteine decarboxylase activity,molecular_function
78317,GO:0050168,Catalysis of the reaction: H2O + pentanamide = NH4 + valerate.,pentanamidase activity,molecular_function
78318,GO:0050170,Catalysis of the reaction: [protein]-C-terminal-L-glutamine + H2O = [protein]-C-terminal-L-glutamate + NH4+.,protein-glutaminase activity,molecular_function
78319,GO:0050172,Catalysis of the reaction: L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O.,phenylalanine 2-monooxygenase activity,molecular_function
78320,GO:0050174,Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.,phenylalanine decarboxylase activity,molecular_function
78321,GO:0050175,Catalysis of the reaction: L-phenylalanine + NAD+ + H2O = 3-phenylpyruvate + NH4+ + NADH + H+.,L-phenylalanine dehydrogenase (NAD+) activity,molecular_function
78322,GO:0050176,Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H+.,L-phenylalanine N-acetyltransferase activity,molecular_function
78323,GO:0050177,Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.,phenylpyruvate decarboxylase activity,molecular_function
78324,GO:0050178,Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.,phenylpyruvate tautomerase activity,molecular_function
78325,GO:0050179,Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.,phenylserine aldolase activity,molecular_function
78326,GO:0050180,Catalysis of the reaction: H2O + phloretin = H+ + phloretate + phloroglucinol.,phloretin hydrolase activity,molecular_function
78327,GO:0050181,"Catalysis of the reaction: H2O + phorbol 12,13-dibutanoate = butanoate + H+ + phorbol 13-butanoate.",phorbol-diester hydrolase activity,molecular_function
78328,GO:0050182,Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.,phosphate butyryltransferase activity,molecular_function
78329,GO:0050183,Catalysis of the reaction: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O.,phosphatidylcholine 12-monooxygenase activity,molecular_function
78330,GO:0050184,"Catalysis of the reaction: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-lipid omega-6 desaturase (cytochrome b5) activity,molecular_function
78331,GO:0050185,Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H2O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+.,phosphatidylinositol deacylase activity,molecular_function
78332,GO:0050186,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.",phosphoadenylylsulfatase activity,molecular_function
78333,GO:0050187,Catalysis of the reaction: N-phosphocreatine + H2O = creatine + phosphate.,phosphoamidase activity,molecular_function
78334,GO:0050188,Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.,phosphoenolpyruvate mutase activity,molecular_function
78335,GO:0050189,Catalysis of the reaction: H2O + phosphoenolpyruvate = phosphate + pyruvate.,phosphoenolpyruvate phosphatase activity,molecular_function
78336,GO:0050190,"Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H+.",phosphoglucokinase activity,molecular_function
78337,GO:0050191,Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H+.,phosphoglycerate kinase (GTP) activity,molecular_function
78338,GO:0050192,Catalysis of the reaction: 2-phospho-D-glycerate + H2O = D-glycerate + phosphate.,phosphoglycerate phosphatase activity,molecular_function
78339,GO:0050193,Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.,phosphoketolase activity,molecular_function
78340,GO:0050194,Catalysis of the reaction: H2O + phosphonoacetaldehyde = acetaldehyde + H+ + phosphate.,phosphonoacetaldehyde hydrolase activity,molecular_function
78341,GO:0050195,"Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H+.",phosphoribokinase activity,molecular_function
78342,GO:0050196,Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.,[phosphorylase] phosphatase activity,molecular_function
78343,GO:0050197,Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H+ + phytanoyl-CoA.,phytanate-CoA ligase activity,molecular_function
78344,GO:0050198,Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H+ + 3 malonyl-CoA = 4 CO2 + 4 CoA + pinosylvin.,pinosylvin synthase activity,molecular_function
78345,GO:0050199,"Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H+.",piperidine N-piperoyltransferase activity,molecular_function
78346,GO:0050201,Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H+.,fucokinase activity,molecular_function
78347,GO:0050202,Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH4.,octopamine dehydratase activity,molecular_function
78348,GO:0050203,Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H+ + oxalyl-CoA.,oxalate-CoA ligase activity,molecular_function
78349,GO:0050204,Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.,oxalomalate lyase activity,molecular_function
78350,GO:0050205,Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.,oxamate carbamoyltransferase activity,molecular_function
78351,GO:0050206,Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.,oximinotransferase activity,molecular_function
78352,GO:0050207,"Catalysis of the reaction:1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O.",plasmanylethanolamine desaturase activity,molecular_function
78353,GO:0050208,"Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.",polysialic-acid O-acetyltransferase activity,molecular_function
78354,GO:0050209,Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.,polyvinyl-alcohol oxidase activity,molecular_function
78355,GO:0050210,Catalysis of the reaction: dimethylallyl diphosphate + H2O = diphosphate + prenol.,prenyl-diphosphatase activity,molecular_function
78356,GO:0050211,Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.,procollagen galactosyltransferase activity,molecular_function
78357,GO:0050212,Catalysis of the reaction: progesterone + reduced [NADPH-hemoprotein reductase] + O2 = 11alpha-hydroxyprogesterone + oxidized [NADPH-hemoprotein reductase] + H2O + H+.,progesterone 11-alpha-monooxygenase activity,molecular_function
78358,GO:0050214,Catalysis of the reaction: AH2 + O2 + progesterone = A + H2O + testosterone acetate.,progesterone monooxygenase activity,molecular_function
78359,GO:0050215,"Catalysis of the reaction: propane-1,2-diol = H2O + propanal.",propanediol dehydratase activity,molecular_function
78360,GO:0050216,"Catalysis of the reaction: NAD+ + propane-1,2-diol 1-phosphate = H+ + hydroxyacetone phosphate + NADH.",propanediol-phosphate dehydrogenase activity,molecular_function
78361,GO:0050217,Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.,propioin synthase activity,molecular_function
78362,GO:0050218,Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.,propionate-CoA ligase activity,molecular_function
78363,GO:0050219,Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.,prostaglandin-A1 delta-isomerase activity,molecular_function
78364,GO:0050220,Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).,prostaglandin-E synthase activity,molecular_function
78365,GO:0050221,"Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.",prostaglandin E2 9-reductase activity,molecular_function
78366,GO:0050223,"Catalysis of the reaction: 3,4-dihydroxybenzoate + H+ = catechol + CO2.",protocatechuate decarboxylase activity,molecular_function
78367,GO:0050224,Catalysis of the reaction: (R)-prunasin + H2O = D-glucose + mandelonitrile.,prunasin beta-glucosidase activity,molecular_function
78368,GO:0050225,Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H+ + pseudouridine 5'-phosphate.,pseudouridine kinase activity,molecular_function
78369,GO:0050226,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.",psychosine sulfotransferase activity,molecular_function
78370,GO:0050227,"Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.",pteridine oxidase activity,molecular_function
78371,GO:0050228,"Catalysis of the reaction: a 2-amino-4-hydroxypteridine + H2O + H+ = a 2,4-dihydroxypteridine + NH4+.",pterin deaminase activity,molecular_function
78372,GO:0050230,"Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.",purine imidazole-ring cyclase activity,molecular_function
78373,GO:0050231,Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H+ + phosphate.,putrescine carbamoyltransferase activity,molecular_function
78374,GO:0050232,Catalysis of the reaction: H2O + O2 + putrescine = 4-aminobutanal + H2O2 + NH4+.,putrescine oxidase activity,molecular_function
78375,GO:0050233,Catalysis of the reaction: D-glucose + O2 = 2-dehydro-D-glucose + H2O2.,pyranose oxidase activity,molecular_function
78376,GO:0050234,Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H2O.,pyrazolylalanine synthase activity,molecular_function
78377,GO:0050235,Catalysis of the reaction: NAD+ + pyridoxal = 4-pyridoxolactone + H+ + NADH.,pyridoxal 4-dehydrogenase activity,molecular_function
78378,GO:0050236,Catalysis of the reaction: NADP+ + pyridoxine = H+ + NADPH + pyridoxal.,pyridoxine 4-dehydrogenase (NADP+) activity,molecular_function
78379,GO:0050237,Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.,pyridoxine 4-oxidase activity,molecular_function
78380,GO:0050238,Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.,pyridoxine 5-dehydrogenase activity,molecular_function
78381,GO:0050239,Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H2O + H+ = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH4+.,pyrithiamine deaminase activity,molecular_function
78382,GO:0050240,Catalysis of the reaction: O2 + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H+.,"pyrogallol 1,2-oxygenase activity",molecular_function
78383,GO:0050241,Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.,pyrroline-2-carboxylate reductase activity,molecular_function
78384,GO:0050242,Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H+ + phosphoenolpyruvate.,"pyruvate, phosphate dikinase activity",molecular_function
78385,GO:0050243,Catalysis of the reaction: CoA + NADP+ + pyruvate = acetyl-CoA + CO2 + NADPH.,pyruvate dehydrogenase (NADP+) activity,molecular_function
78386,GO:0050244,Catalysis of the reaction: CoA + H+ + O2 + pyruvate = acetyl-CoA + CO2 + H2O2.,pyruvate oxidase (CoA-acetylating) activity,molecular_function
78387,GO:0050247,Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine.,raucaffricine beta-glucosidase activity,molecular_function
78388,GO:0050248,Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.,Renilla-luciferin 2-monooxygenase activity,molecular_function
78389,GO:0050249,"Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H+ + luciferyl sulfate.",Renilla-luciferin sulfotransferase activity,molecular_function
78390,GO:0050251,Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.,retinol isomerase activity,molecular_function
78391,GO:0050252,Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.,retinol O-fatty-acyltransferase activity,molecular_function
78392,GO:0050253,Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.,retinyl-palmitate esterase activity,molecular_function
78393,GO:0050254,Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.,rhodopsin kinase activity,molecular_function
78394,GO:0050255,Catalysis of the reaction: D-ribitol + NAD+ = D-ribulose + H+ + NADH.,ribitol 2-dehydrogenase (NAD+) activity,molecular_function
78395,GO:0050256,Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.,ribitol-5-phosphate 2-dehydrogenase [NAD(P)+] activity,molecular_function
78396,GO:0050257,Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.,riboflavin phosphotransferase activity,molecular_function
78397,GO:0050258,Catalysis of the reaction: H2O + H+ + riboflavin = D-ribitol + lumichrome.,riboflavinase activity,molecular_function
78398,GO:0050259,Catalysis of the reaction: H2O + NADP+ + ribofuranose = D-ribonate + 2 H+ + NADPH.,ribose 1-dehydrogenase (NADP+) activity,molecular_function
78399,GO:0050260,Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH4 = 5-phospho-D-ribosylamine + ADP + 2 H+ + phosphate.,ribose-5-phosphate-ammonia ligase activity,molecular_function
78400,GO:0050261,Catalysis of the reaction: aldehydo-D-ribose = D-ribulose.,ribose isomerase activity,molecular_function
78401,GO:0050262,Catalysis of the reaction: beta-nicotinamide D-riboside + ATP = beta-nicotinamide D-ribonucleotide + ADP + H+.,ribosylnicotinamide kinase activity,molecular_function
78402,GO:0050263,Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.,ribosylpyrimidine nucleosidase activity,molecular_function
78403,GO:0050264,Catalysis of the reaction: 2 H+ + O2 + rifamycin B = H2O2 + rifamycin O.,rifamycin-B oxidase activity,molecular_function
78404,GO:0050265,Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).,RNA uridylyltransferase activity,molecular_function
78405,GO:0050266,"Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.",rosmarinate synthase activity,molecular_function
78406,GO:0050267,Catalysis of the reaction: (cis-prenyl)n-diphosphate + isopentenyl diphosphate = (cis-prenyl)(n+1)-diphosphate + diphosphate.,rubber cis-polyprenylcistransferase activity,molecular_function
78407,GO:0050268,Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.,coniferyl-alcohol dehydrogenase activity,molecular_function
78408,GO:0050269,Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.,coniferyl-aldehyde dehydrogenase [NAD(P)+] activity,molecular_function
78409,GO:0050270,Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O + H+ = S-inosyl-L-homocysteine + NH4.,S-adenosylhomocysteine deaminase activity,molecular_function
78410,GO:0050272,Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H+.,S-carboxymethylcysteine synthase activity,molecular_function
78411,GO:0050273,Catalysis of the reaction: S-succinylglutathione + H2O = glutathione + H+ + succinate.,S-succinylglutathione hydrolase activity,molecular_function
78412,GO:0050274,Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H+ + salicin + UDP.,salicyl-alcohol beta-D-glucosyltransferase activity,molecular_function
78413,GO:0050275,Catalysis of the reaction: scopoletin + UDP-D-glucose = H+ + scopolin + UDP.,scopoletin glucosyltransferase activity,molecular_function
78414,GO:0050276,Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H+.,scyllo-inosamine 4-kinase activity,molecular_function
78415,GO:0050277,Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H+ + sedoheptulose 7-phosphate.,sedoheptulokinase activity,molecular_function
78416,GO:0050278,"Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.",sedoheptulose-bisphosphatase activity,molecular_function
78417,GO:0050279,Catalysis of the reaction: L-sepiapterin + H2O + H+ = (S)-xanthopterin-B2 + NH4+.,sepiapterin deaminase activity,molecular_function
78418,GO:0050280,"Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADH.",sequoyitol dehydrogenase activity,molecular_function
78419,GO:0050281,Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.,L-serine:glyoxylate transaminase activity,molecular_function
78420,GO:0050282,Catalysis of the reaction: L-serine + NAD+ + H2O = 3-hydroxypyruvate + NH4+ + NADH + H+.,L-serine 2-dehydrogenase (NAD+) activity,molecular_function
78421,GO:0050283,Catalysis of the reaction: -serine O-sulfate + H2O = sulfate + pyruvate + NH4+ + H+.,serine-sulfate ammonia-lyase activity,molecular_function
78422,GO:0050284,Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.,sinapate 1-glucosyltransferase activity,molecular_function
78423,GO:0050285,Catalysis of the reaction: O-sinapoylcholine + H2O = choline + H+ + sinapate.,sinapine esterase activity,molecular_function
78424,GO:0050286,Catalysis of the reaction: D-glucitol 6-phosphate + H2O = D-glucitol + phosphate.,sorbitol-6-phosphatase activity,molecular_function
78425,GO:0050287,Catalysis of the reaction: L-sorbose + NADP+ = 5-dehydro-D-fructose + H+ + NADPH.,sorbose 5-dehydrogenase (NADP+) activity,molecular_function
78426,GO:0050288,Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).,sorbose dehydrogenase activity,molecular_function
78427,GO:0050289,"Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.",spermidine dehydrogenase activity,molecular_function
78428,GO:0050290,Catalysis of the reaction: H2O + sphingomyelin = ceramide 1-phosphate + choline + H+.,sphingomyelin phosphodiesterase D activity,molecular_function
78429,GO:0050291,Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.,sphingosine N-acyltransferase activity,molecular_function
78430,GO:0050292,"Catalysis of the reaction: AH2 + O2 + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O.",steroid 9-alpha-monooxygenase activity,molecular_function
78431,GO:0050293,Catalysis of the reaction: H2O + testololactone = H+ + testolate.,steroid-lactonase activity,molecular_function
78432,GO:0050294,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.",steroid sulfotransferase activity,molecular_function
78433,GO:0050295,Catalysis of the reaction: cholesteryl-beta-D-glucoside + H2O = D-glucose + cholesterol.,steryl-beta-glucosidase activity,molecular_function
78434,GO:0050296,Catalysis of the reaction: H2O + stipitatonate = CO2 + H+ + stipitatate.,stipitatonate decarboxylase activity,molecular_function
78435,GO:0050297,"Catalysis of the reaction: L-dopa + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H+.",stizolobate synthase activity,molecular_function
78436,GO:0050298,"Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.",stizolobinate synthase activity,molecular_function
78437,GO:0050299,Catalysis of the reaction: ATP + streptomycin = ADP + 2 H+ + streptomycin 3''-phosphate.,streptomycin 3''-kinase activity,molecular_function
78438,GO:0050300,Catalysis of the reaction: ATP + streptomycin = ADP + 2 H+ + streptomycin 6-phosphate.,aminoglycoside 6-kinase activity,molecular_function
78439,GO:0050301,Catalysis of the reaction: H2O + streptomycin 6-phosphate = phosphate + streptomycin.,streptomycin-6-phosphatase activity,molecular_function
78440,GO:0050302,Catalysis of the reaction: H2O + indole-3-acetaldehyde + O2 = (indol-3-yl)acetate + H+ + H2O2.,indole-3-acetaldehyde oxidase activity,molecular_function
78441,GO:0050303,"Catalysis of the reaction: L-lysine + NAD+ = L-1-piperideine-6-carboxylate + NH4+ + NADH + 2 H+. (S)-(2-aminoethyl)-L-cysteine can act as a substrate, and NADP+ can act as the acceptor.",L-lysine 6-dehydrogenase activity,molecular_function
78442,GO:0050304,Catalysis of the reaction: H2O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.,nitrous-oxide reductase activity,molecular_function
78443,GO:0050305,Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H2O + NAD+ = glycine + H+ + NADH + pyruvate.,strombine dehydrogenase activity,molecular_function
78444,GO:0050306,Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.,sucrose 1F-fructosyltransferase activity,molecular_function
78445,GO:0050307,Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.,sucrose-phosphate phosphatase activity,molecular_function
78446,GO:0050308,Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.,sugar-phosphatase activity,molecular_function
78447,GO:0050309,Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.,sugar-terminal-phosphatase activity,molecular_function
78448,GO:0050310,Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.,sulfite dehydrogenase activity,molecular_function
78449,GO:0050311,Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.,sulfite reductase (ferredoxin) activity,molecular_function
78450,GO:0050313,Catalysis of the reaction: S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H+.,sulfur dioxygenase activity,molecular_function
78451,GO:0050314,"Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H+.",sym-norspermidine synthase activity,molecular_function
78452,GO:0050315,Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.,synephrine dehydratase activity,molecular_function
78453,GO:0050316,Catalysis of the reaction: dGMP + ATP = dGDP + ADP.,dGMP kinase activity,molecular_function
78454,GO:0050317,Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H+.,tagatose kinase activity,molecular_function
78455,GO:0050318,Catalysis of the reaction: digallate + H2O = 2 gallate + H+.,tannase activity,molecular_function
78456,GO:0050319,Catalysis of the reaction: L-tartrate + H+ = D-glycerate + CO2.,tartrate decarboxylase activity,molecular_function
78457,GO:0050320,"Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.",tartrate epimerase activity,molecular_function
78458,GO:0050321,Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein on serine and threonine residues.,tau-protein kinase activity,molecular_function
78459,GO:0050322,Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.,taurine:2-oxoglutarate transaminase activity,molecular_function
78460,GO:0050323,Catalysis of the reaction: A + H2O + taurine = AH(2) + NH4 + sulfoacetaldehyde.,taurine dehydrogenase activity,molecular_function
78461,GO:0050324,Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H+.,taurocyamine kinase activity,molecular_function
78462,GO:0050325,Catalysis of the reaction: H2O + NAD+ + tauropine = H+ + NADH + pyruvate + taurine.,tauropine dehydrogenase activity,molecular_function
78463,GO:0050326,"Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.",taxifolin 8-monooxygenase activity,molecular_function
78464,GO:0050328,Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.,tetrahydroberberine oxidase activity,molecular_function
78465,GO:0050329,Catalysis of the reaction: tetrahydroxypteridine = H+ + xanthine-8-carboxylate.,tetrahydroxypteridine cycloisomerase activity,molecular_function
78466,GO:0050330,Catalysis of the reaction: N(5)-ethyl-L-glutamine + H2O = L-glutamate + ethylamine.,theanine hydrolase activity,molecular_function
78467,GO:0050331,Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.,thiamine-diphosphate kinase activity,molecular_function
78468,GO:0050332,Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.,thiamine pyridinylase activity,molecular_function
78469,GO:0050333,Catalysis of the reaction: H2O + thiamine triphosphate = thiamine diphosphate + H+ + phosphate.,thiamine triphosphate phosphatase activity,molecular_function
78470,GO:0050334,Catalysis of the reaction: H2O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H+.,thiaminase activity,molecular_function
78471,GO:0050336,Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.,thioethanolamine S-acetyltransferase activity,molecular_function
78472,GO:0050337,Catalysis of the reaction: thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H+.,thiosulfate-thiol sulfurtransferase activity,molecular_function
78473,GO:0050338,Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.,thiosulfate dehydrogenase activity,molecular_function
78474,GO:0050339,Catalysis of the reaction: dTTP + H2O = dTDP + H+ + phosphate.,TTPase activity,molecular_function
78475,GO:0050341,Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.,thymine dioxygenase activity,molecular_function
78476,GO:0050342,"Catalysis of the reaction: gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + H+ + S-adenosyl-L-homocysteine. This reaction can also use delta-tocopherol, gamma-tocotrienol and delta-tocotrienol as substrates.",tocopherol C-methyltransferase activity,molecular_function
78477,GO:0050343,Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.,trans-2-enoyl-CoA reductase (NADH) activity,molecular_function
78478,GO:0050344,Catalysis of the reaction: trans-cinnamate + H+ + NADPH + O2 = 2-coumarate + H2O + NADP+.,trans-cinnamate 2-monooxygenase activity,molecular_function
78479,GO:0050345,"Catalysis of the reaction: trans-2,3-epoxysuccinate + H2O = (2R,3S)-tartrate.",trans-epoxysuccinate hydrolase activity,molecular_function
78480,GO:0050346,Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H2O + H+.,trans-L-3-hydroxyproline dehydratase activity,molecular_function
78481,GO:0050348,"Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.",trehalose O-mycolyltransferase activity,molecular_function
78482,GO:0050349,Catalysis of the reaction: H2O + triacetate lactone = triacetate.,triacetate-lactonase activity,molecular_function
78483,GO:0050350,"Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2.",trihydroxystilbene synthase activity,molecular_function
78484,GO:0050351,Catalysis of the reaction: H2O + trimetaphosphate = 2 H+ + triphosphate.,trimetaphosphatase activity,molecular_function
78485,GO:0050352,Catalysis of the reaction: H+ + trimethylamine N-oxide = dimethylamine + formaldehyde.,trimethylamine-oxide aldolase activity,molecular_function
78486,GO:0050353,"Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate.",trimethyllysine dioxygenase activity,molecular_function
78487,GO:0050354,Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H+.,triokinase activity,molecular_function
78488,GO:0050355,Catalysis of the reaction: H2O + inorganic triphosphate = diphosphate + phosphate.,inorganic triphosphate phosphatase activity,molecular_function
78489,GO:0050356,Catalysis of the reaction: NADP+ + tropine = H+ + NADPH + tropinone.,tropine dehydrogenase activity,molecular_function
78490,GO:0050357,Catalysis of the reaction: atropine + H2O = H+ + tropate + tropine.,tropinesterase activity,molecular_function
78491,GO:0050358,Catalysis of the reaction: NADP+ + pseudotropine = H+ + NADPH + tropinone.,tropinone reductase activity,molecular_function
78492,GO:0050360,Catalysis of the reaction: L-tryptophan + O2 + H+ = 3-indoleglycolaldehyde + NH4+ + CO2.,tryptophan 2'-dioxygenase activity,molecular_function
78493,GO:0050361,Catalysis of the reaction: L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide.,tryptophan 2-monooxygenase activity,molecular_function
78494,GO:0050362,Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indole-3-pyruvate + L-glutamate.,L-tryptophan:2-oxoglutarate transaminase activity,molecular_function
78495,GO:0050363,Catalysis of the reaction: L-tryptophan + NAD(P)+ + H2O = indole-3-pyruvate + NH4+ + NAD(P)H + H+.,L-tryptophan dehydrogenase [NAD(P)+] activity,molecular_function
78496,GO:0050364,Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.,tryptophan dimethylallyltransferase activity,molecular_function
78497,GO:0050365,Catalysis of the reaction: L-tryptophanamide + H2O = L-tryptophan + NH4.,tryptophanamidase activity,molecular_function
78498,GO:0050366,Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.,tyramine N-feruloyltransferase activity,molecular_function
78499,GO:0050367,Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H+.,tyrosine-arginine ligase activity,molecular_function
78500,GO:0050368,Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.,"L-tyrosine 2,3-aminomutase activity",molecular_function
78501,GO:0050369,Catalysis of the reaction: ATP + L-seryl-[tyrosine-3-monooxygenase] = ADP + H+ + O-phospho-L-seryl-[tyrosine-3-monooxygenase].,[tyrosine 3-monooxygenase] kinase activity,molecular_function
78502,GO:0050370,Catalysis of the reaction: L-tyrosine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-4-hydroxyphenylacetaldehyde oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H+.,tyrosine N-monooxygenase activity,molecular_function
78503,GO:0050371,Catalysis of the reaction: L-tyrosine + H2O = NH4 + phenol + pyruvate.,tyrosine phenol-lyase activity,molecular_function
78504,GO:0050373,Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.,UDP-arabinose 4-epimerase activity,molecular_function
78505,GO:0050374,Catalysis of the reaction: H+ + UDP-alpha-D-galacturonate = CO2 + UDP-L-arabinose.,UDP-galacturonate decarboxylase activity,molecular_function
78506,GO:0050376,Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.,UDP-glucosamine 4-epimerase activity,molecular_function
78507,GO:0050377,Catalysis of the reaction: UDP-D-glucose = H2O + UDP-4-dehydro-6-deoxy-D-glucose.,"UDP-glucose 4,6-dehydratase activity",molecular_function
78508,GO:0050378,Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.,UDP-glucuronate 4-epimerase activity,molecular_function
78509,GO:0050379,Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.,UDP-glucuronate 5'-epimerase activity,molecular_function
78510,GO:0050380,"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.",undecaprenyl-diphosphatase activity,molecular_function
78511,GO:0050382,Catalysis of the reaction: H+ + uracil 5-carboxylate = CO2 + uracil.,uracil-5-carboxylate decarboxylase activity,molecular_function
78512,GO:0050383,Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.,uracil dehydrogenase activity,molecular_function
78513,GO:0050384,Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H+ + urate.,urate-ribonucleotide phosphorylase activity,molecular_function
78514,GO:0050385,Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.,ureidoglycolate lyase activity,molecular_function
78515,GO:0050386,Catalysis of the reaction: N-carbamoyl-L-aspartate + H2O + 2 H+ = L-aspartate + CO2 + NH4.,ureidosuccinase activity,molecular_function
78516,GO:0050387,Catalysis of the reaction: H2O + H+ + urethane = CO2 + ethanol + NH4.,urethanase activity,molecular_function
78517,GO:0050388,Catalysis of the reaction: D-galacturonate + H2O + NAD+ = galactarate + 2 H+ + NADH.,uronate dehydrogenase activity,molecular_function
78518,GO:0050389,"Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.",uronolactonase activity,molecular_function
78519,GO:0050390,Catalysis of the reaction: L-valine + H+ = 2-methylpropanamine + CO2.,valine decarboxylase activity,molecular_function
78520,GO:0050391,Catalysis of the reaction: L-valine + NADP+ + H2O = 3-methyl-2-oxobutanoate + NH4+ + NADPH + H+.,L-valine dehydrogenase (NADP+) activity,molecular_function
78521,GO:0050392,Catalysis of the reaction: (R)-vicianin + H2O = mandelonitrile + vicianose.,vicianin beta-glucosidase activity,molecular_function
78522,GO:0050393,Catalysis of the reaction: vinylacetyl-CoA = (2E)-butenoyl-CoA.,vinylacetyl-CoA delta-isomerase activity,molecular_function
78523,GO:0050394,Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.,viomycin kinase activity,molecular_function
78524,GO:0050395,Catalysis of the reaction: UDP-D-glucose + vitexin = H+ + UDP + vitexin 2''-O-beta-D-glucoside.,vitexin beta-glucosyltransferase activity,molecular_function
78525,GO:0050396,"Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD+ = (6S)-6-hydroxy-3-oxo-alpha-ionone + H+ + NADH.",vomifoliol 4'-dehydrogenase activity,molecular_function
78526,GO:0050397,Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.,Watasenia-luciferin 2-monooxygenase activity,molecular_function
78527,GO:0050398,Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.,wax-ester hydrolase activity,molecular_function
78528,GO:0050399,"Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD+ = H+ + NADH + xanthommatin.",xanthommatin reductase activity,molecular_function
78529,GO:0050400,Catalysis of the reaction: ATP + xylitol = ADP + 2 H+ + xylitol 5-phosphate.,xylitol kinase activity,molecular_function
78530,GO:0050401,Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.,xylonate dehydratase activity,molecular_function
78531,GO:0050402,"Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.","xylono-1,4-lactonase activity",molecular_function
78532,GO:0050403,Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H+ + UDP.,trans-zeatin O-beta-D-glucosyltransferase activity,molecular_function
78533,GO:0050404,Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H+ + UDP.,zeatin O-beta-D-xylosyltransferase activity,molecular_function
78534,GO:0050406,Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.,[acetyl-CoA carboxylase]-phosphatase activity,molecular_function
78535,GO:0050407,Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.,[glycogen-synthase-D] phosphatase activity,molecular_function
78536,GO:0050408,Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.,[pyruvate kinase]-phosphatase activity,molecular_function
78537,GO:0050409,Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H+ + UDP.,indolylacetylinositol arabinosyltransferase activity,molecular_function
78538,GO:0050410,Catalysis of the reaction: 3-oxododecanoate + H+ = 2-undecanone + CO2. Also decarboxylates other C14 to C16 oxo acids.,3-oxolaurate decarboxylase activity,molecular_function
78539,GO:0050412,Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.,cinnamate beta-D-glucosyltransferase activity,molecular_function
78540,GO:0050413,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.",D-alanine 2-hydroxymethyltransferase activity,molecular_function
78541,GO:0050414,Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH4+.,formimidoylaspartate deiminase activity,molecular_function
78542,GO:0050415,Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.,formimidoylglutamase activity,molecular_function
78543,GO:0050416,Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH4+.,formimidoylglutamate deiminase activity,molecular_function
78544,GO:0050417,Catalysis of the reactions: H2O + L-glutamine = NH4 + L-glutamate; and H2O + L-asparagine = NH4 + L-aspartate.,glutamin-(asparagin-)ase activity,molecular_function
78545,GO:0050418,Catalysis of the reaction: an acceptor + NH4+ + H2O = hydroxylamine + a reduced acceptor + H+.,hydroxylamine reductase activity,molecular_function
78546,GO:0050419,Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.,hydroxymandelonitrile lyase activity,molecular_function
78547,GO:0050420,Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.,maltose synthase activity,molecular_function
78548,GO:0050421,Catalysis of the reaction: nitric oxide + Fe(III)-[cytochrome c] + H2O = Fe(II)-[cytochrome c] + nitrite + 2 H+.,nitrite reductase (NO-forming) activity,molecular_function
78549,GO:0050422,Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone.,strictosidine beta-glucosidase activity,molecular_function
78550,GO:0050423,Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.,thiamine oxidase activity,molecular_function
78551,GO:0050427,"The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.",3'-phosphoadenosine 5'-phosphosulfate metabolic process,biological_process
78552,GO:0050428,"The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.",3'-phosphoadenosine 5'-phosphosulfate biosynthetic process,biological_process
78553,GO:0050431,"Binding to TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.",transforming growth factor beta binding,molecular_function
78554,GO:0050432,"The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.",catecholamine secretion,biological_process
78555,GO:0050433,"Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.",regulation of catecholamine secretion,biological_process
78556,GO:0050434,"Any process that activates or increases the frequency, rate or extent of viral transcription.",positive regulation of viral transcription,biological_process
78557,GO:0050435,"The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).",amyloid-beta metabolic process,biological_process
78558,GO:0050436,"Binding to a microfibril, any small fibril occurring in biological material.",microfibril binding,molecular_function
78559,GO:0050437,Catalysis of the reaction: geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate.,(-)-endo-fenchol synthase activity,molecular_function
78560,GO:0050438,Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H2O = (R)-2-ethylmalate + CoA + H+.,2-ethylmalate synthase activity,molecular_function
78561,GO:0050439,Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H+ = 2-hydroxy-3-oxoadipate + CO2.,2-hydroxy-3-oxoadipate synthase activity,molecular_function
78562,GO:0050440,"Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+.",2-methylcitrate synthase activity,molecular_function
78563,GO:0050441,Catalysis of the reaction: butanoyl-CoA + glyoxylate + H2O = 3-ethylmalate + CoA + H+.,3-ethylmalate synthase activity,molecular_function
78564,GO:0050442,Catalysis of the reaction: glyoxylate + H2O + pentanoyl-CoA = 3-propylmalate + CoA + H+.,3-propylmalate synthase activity,molecular_function
78565,GO:0050445,Catalysis of the reaction: 3-sulfanyl-2-(sulfanylmethyl)propanoate + NAD+ = asparagusate + NADH + H+.,asparagusate reductase (NADH) activity,molecular_function
78566,GO:0050446,"Catalysis of the reaction: aniline + N,N-dimethyl-1,4-phenylenediamine + 2 NADP+ = 4-(dimethylamino)azobenzene + 2 H+ + 2 NADPH.",azobenzene reductase (NADP+) activity,molecular_function
78567,GO:0050447,Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H+.,zeatin 9-aminocarboxyethyltransferase activity,molecular_function
78568,GO:0050448,Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).,beta-cyclopiazonate dehydrogenase activity,molecular_function
78569,GO:0050449,Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.,casbene synthase activity,molecular_function
78570,GO:0050451,Catalysis of the reaction: 2 CoA + NADP+ = CoA-disulfide + NADPH + H+.,CoA-disulfide reductase (NADPH) activity,molecular_function
78571,GO:0050452,Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.,CoA-glutathione reductase (NADPH) activity,molecular_function
78572,GO:0050454,Catalysis of the reaction: coenzyme F420 + H(2) + H+ = reduced coenzyme F420.,coenzyme F420 hydrogenase activity,molecular_function
78573,GO:0050455,Catalysis of the reaction: 2 columbamine + O2 = 2 berberine + 2 H2O.,columbamine oxidase activity,molecular_function
78574,GO:0050456,Catalysis of the reaction: 2 L-cysteine + NAD+ = L-cystine + H+ + NADH.,L-cystine reductase (NADH) activity,molecular_function
78575,GO:0050457,"Catalysis of the reaction: H2O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H+.",decylcitrate synthase activity,molecular_function
78576,GO:0050458,"Catalysis of the reaction: 2-oxoglutarate + H2O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H+.",decylhomocitrate synthase activity,molecular_function
78577,GO:0050459,Catalysis of the reaction: H2O + phosphoethanolamine = acetaldehyde + NH4 + phosphate.,ethanolamine-phosphate phospho-lyase activity,molecular_function
78578,GO:0050460,Catalysis of the reaction: NH4+ + NAD+ + H2O = hydroxylamine + NADH + 2 H+.,hydroxylamine reductase (NADH) activity,molecular_function
78579,GO:0050461,"Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.",L-mimosine synthase activity,molecular_function
78580,GO:0050462,Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.,N-acetylneuraminate synthase activity,molecular_function
78581,GO:0050463,Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.,nitrate reductase [NAD(P)H] activity,molecular_function
78582,GO:0050464,Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.,nitrate reductase (NADPH) activity,molecular_function
78583,GO:0050465,Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.,nitroquinoline-N-oxide reductase [NAD(P)H] activity,molecular_function
78584,GO:0050467,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.",pentalenene synthase activity,molecular_function
78585,GO:0050468,"Catalysis of the reaction: (S)-reticuline + O2 = (S)-scoulerine + H2O2 + H+. Also acts on related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)- tetrahydroprotoberberines.",reticuline oxidase activity,molecular_function
78586,GO:0050469,Catalysis of the reaction: geranyl diphosphate + H2O = diphosphate + sabinene hydrate.,sabinene-hydrate synthase activity,molecular_function
78587,GO:0050470,Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.,trimethylamine dehydrogenase activity,molecular_function
78588,GO:0050471,Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.,uracilylalanine synthase activity,molecular_function
78589,GO:0050472,Catalysis of the reaction: dihydrozeatin + NADP+ = H+ + NADPH + zeatin.,zeatin reductase activity,molecular_function
78590,GO:0050473,"Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.",arachidonate 15-lipoxygenase activity,molecular_function
78591,GO:0050474,"Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.",(S)-norcoclaurine synthase activity,molecular_function
78592,GO:0050476,Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.,acetylenedicarboxylate decarboxylase activity,molecular_function
78593,GO:0050477,Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.,acyl-lysine deacylase activity,molecular_function
78594,GO:0050479,Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).,glyceryl-ether monooxygenase activity,molecular_function
78595,GO:0050480,"Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H2O = N-formimidoyl-L-glutamate + H+.",imidazolonepropionase activity,molecular_function
78596,GO:0050481,"Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O2 = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H2O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.",mandelate 4-monooxygenase activity,molecular_function
78597,GO:0050482,The controlled release of arachidonic acid from a cell or a tissue.,arachidonate secretion,biological_process
78598,GO:0050485,Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.,"oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor",molecular_function
78599,GO:0050486,Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.,intramolecular hydroxytransferase activity,molecular_function
78600,GO:0050487,Catalysis of the reaction: acetyl phosphate + H+ + sulfite = phosphate + sulfoacetaldehyde.,sulfoacetaldehyde acetyltransferase activity,molecular_function
78601,GO:0050488,Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.,ecdysteroid UDP-glucosyltransferase activity,molecular_function
78602,GO:0050490,"Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.","1,4-lactonase activity",molecular_function
78603,GO:0050491,Catalysis of the reaction: NAD+ + sulcatol = H+ + NADH + sulcatone.,sulcatone reductase activity,molecular_function
78604,GO:0050492,Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.,glycerol-1-phosphate dehydrogenase [NAD(P)+] activity,molecular_function
78605,GO:0050497,Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).,alkylthioltransferase activity,molecular_function
78606,GO:0050498,"Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated",molecular_function
78607,GO:0050499,Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.,"oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor",molecular_function
78608,GO:0050500,Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.,"1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity",molecular_function
78609,GO:0050501,Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.,hyaluronan synthase activity,molecular_function
78610,GO:0050502,Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H+ + UDP.,cis-zeatin O-beta-D-glucosyltransferase activity,molecular_function
78611,GO:0050503,Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.,trehalose 6-phosphate phosphorylase activity,molecular_function
78612,GO:0050504,Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H+.,mannosyl-3-phosphoglycerate synthase activity,molecular_function
78613,GO:0050505,Catalysis of the reaction: hydroquinone + UDP-D-glucose = H+ + hydroquinone O-beta-D-glucopyranoside + UDP.,hydroquinone glucosyltransferase activity,molecular_function
78614,GO:0050506,Catalysis of the reaction: UDP-D-glucose + vomilenine = H+ + raucaffricine + UDP.,vomilenine glucosyltransferase activity,molecular_function
78615,GO:0050507,Catalysis of the reaction: indoxyl + UDP-D-glucose = H+ + indican + UDP.,indoxyl-UDPG glucosyltransferase activity,molecular_function
78616,GO:0050508,Catalysis of the reaction: 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + H+ + UDP.,glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity,molecular_function
78617,GO:0050509,Catalysis of the reaction: 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + H+ + UDP.,N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity,molecular_function
78618,GO:0050510,"Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.",N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,molecular_function
78619,GO:0050511,"Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-glucosamine = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamm-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H+ + UDP.",undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity,molecular_function
78620,GO:0050512,"Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.",lactosylceramide 4-alpha-galactosyltransferase activity,molecular_function
78621,GO:0050513,Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acet...,glycoprotein 2-beta-D-xylosyltransferase activity,molecular_function
78622,GO:0050514,"Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.",homospermidine synthase (spermidine-specific) activity,molecular_function
78623,GO:0050515,Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H+.,4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity,molecular_function
78624,GO:0050518,Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.,2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity,molecular_function
78625,GO:0050519,Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.,holo-citrate lyase synthase activity,molecular_function
78626,GO:0050520,"Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H+.",phosphatidylcholine synthase activity,molecular_function
78627,GO:0050521,Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-6-phospho-alpha-D-glucosyl](n) + n AMP + 2n H+ + n phosphate.,"alpha-glucan, water dikinase activity",molecular_function
78628,GO:0050524,"Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.",coenzyme-B sulfoethylthiotransferase activity,molecular_function
78629,GO:0050525,Catalysis of the reaction: cutin + H2O = cutin monomers.,cutinase activity,molecular_function
78630,GO:0050526,Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.,poly(3-hydroxybutyrate) depolymerase activity,molecular_function
78631,GO:0050527,Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.,poly(3-hydroxyoctanoate) depolymerase activity,molecular_function
78632,GO:0050528,Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.,acyloxyacyl hydrolase activity,molecular_function
78633,GO:0050529,Catalysis of the reaction: H2O + polyneuridine aldehyde = 16-epivellosimine + CO2 + methanol.,polyneuridine-aldehyde esterase activity,molecular_function
78634,GO:0050530,Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H2O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.,glucosylglycerol 3-phosphatase activity,molecular_function
78635,GO:0050531,Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.,mannosyl-3-phosphoglycerate phosphatase activity,molecular_function
78636,GO:0050532,Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H2O = (R)-3-sulfolactate + phosphate.,2-phosphosulfolactate phosphatase activity,molecular_function
78637,GO:0050533,"Catalysis of the reaction: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate.",inositol hexakisphosphate 5-phosphatase activity,molecular_function
78638,GO:0050534,Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.,3-deoxyoctulosonase activity,molecular_function
78639,GO:0050535,Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.,beta-primeverosidase activity,molecular_function
78640,GO:0050536,Catalysis of the reaction: N-acetylphenylethylamine + H2O = acetate + phenylethylamine.,(S)-N-acetyl-1-phenylethylamine hydrolase activity,molecular_function
78641,GO:0050537,Catalysis of the reaction: (R)-mandelamide + H2O = (R)-mandelate + NH4.,mandelamide amidase activity,molecular_function
78642,GO:0050538,Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.,N-carbamoyl-L-amino-acid hydrolase activity,molecular_function
78643,GO:0050539,Catalysis of the reaction: H2O + maleimide = H+ + maleamate.,maleimide hydrolase activity,molecular_function
78644,GO:0050540,Catalysis of the reaction: 2-aminomuconate + H2O + H+ = (Z)-5-oxohex-2-enedioate + NH4.,2-aminomuconate deaminase activity,molecular_function
78645,GO:0050541,Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.,"beta,beta-carotene-9',10'-dioxygenase activity",molecular_function
78646,GO:0050542,"Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.",icosanoid binding,molecular_function
78647,GO:0050543,"Binding to icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.",icosatetraenoic acid binding,molecular_function
78648,GO:0050544,"Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.",arachidonate binding,molecular_function
78649,GO:0050545,Catalysis of the reaction: 3-sulfopyruvate + H+ = CO2 + sulfoacetaldehyde.,sulfopyruvate decarboxylase activity,molecular_function
78650,GO:0050546,Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H+ = (4-hydroxyphenyl)acetaldehyde + CO2.,4-hydroxyphenylpyruvate decarboxylase activity,molecular_function
78651,GO:0050547,Catalysis of the reaction: (E)-feruloyl-CoA + H2O = acetyl-CoA + vanillin.,feruloyl-CoA hydratase/lyase activity,molecular_function
78652,GO:0050549,Catalysis of the reaction: N-cyclohexylformamide + H+ = cyclohexyl isocyanide + H2O.,cyclohexyl-isocyanide hydratase activity,molecular_function
78653,GO:0050550,"Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate. This reaction can produce (1R,5R)-alpha-pinene, (1S,5S)-alpha-pinene, (1R,5R)-beta-pinene and (1S,5S)-beta-pinene.",pinene synthase activity,molecular_function
78654,GO:0050551,Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.,myrcene synthase activity,molecular_function
78655,GO:0050552,Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.,(4S)-limonene synthase activity,molecular_function
78656,GO:0050553,"Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.",taxadiene synthase activity,molecular_function
78657,GO:0050554,Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.,abietadiene synthase activity,molecular_function
78658,GO:0050555,"Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.",2-hydroxypropyl-CoM lyase activity,molecular_function
78659,GO:0050556,Catalysis of the reaction: deacetylisoipecoside + H2O = dopamine + secologanin.,deacetylisoipecoside synthase activity,molecular_function
78660,GO:0050557,Catalysis of the reaction: deacetylipecoside + H2O = dopamine + secologanin.,deacetylipecoside synthase activity,molecular_function
78661,GO:0050558,Catalysis of the reaction: alpha-maltose = beta-maltose.,maltose epimerase activity,molecular_function
78662,GO:0050559,Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.,copalyl diphosphate synthase activity,molecular_function
78663,GO:0050560,Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.,aspartate-tRNA(Asn) ligase activity,molecular_function
78664,GO:0050561,Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.,glutamate-tRNA(Gln) ligase activity,molecular_function
78665,GO:0050563,Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate. ADP + phosphate or AMP + diphosphate may be formed in this reaction.,trans-feruloyl-CoA synthase activity,molecular_function
78666,GO:0050564,Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H2O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H+.,N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity,molecular_function
78667,GO:0050565,Catalysis of the reaction: ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine = aerobactin + AMP + diphosphate + H+.,aerobactin synthase activity,molecular_function
78668,GO:0050566,Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.,asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity,molecular_function
78669,GO:0050567,Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,molecular_function
78670,GO:0050568,Catalysis of the reaction: L-glutaminyl-[protein] + H2O = L-glutamyl-[protein] + NH4+.,protein-glutamine glutaminase activity,molecular_function
78671,GO:0050569,Catalysis of the reaction: glycolaldehyde + H2O + NAD+ = glycolate + 2 H+ + NADH.,glycolaldehyde dehydrogenase (NAD+) activity,molecular_function
78672,GO:0050570,Catalysis of the reaction: 4-(phosphooxy)-L-threonine + NAD+ = 3-amino-2-oxopropyl phosphate + CO2 + NADH.,4-hydroxythreonine-4-phosphate dehydrogenase activity,molecular_function
78673,GO:0050571,"Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.","1,5-anhydro-D-fructose reductase activity",molecular_function
78674,GO:0050572,Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.,L-idonate 5-dehydrogenase [NAD(P)+] activity,molecular_function
78675,GO:0050573,Catalysis of the reaction: dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H+ + NADPH.,dTDP-4-dehydro-6-deoxyglucose reductase activity,molecular_function
78676,GO:0050574,Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.,2-(R)-hydroxypropyl-CoM dehydrogenase activity,molecular_function
78677,GO:0050575,Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.,2-(S)-hydroxypropyl-CoM dehydrogenase activity,molecular_function
78678,GO:0050577,Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.,GDP-L-fucose synthase activity,molecular_function
78679,GO:0050578,Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + NADP+ = a 2-oxocarboxylate + NADPH + H+.,(2R)-2-hydroxyacid dehydrogenase (NADP+) activity,molecular_function
78680,GO:0050579,Catalysis of the reaction: 10-deoxysarpagine + NADP+ = H+ + NADPH + vellosimine.,vellosimine dehydrogenase activity,molecular_function
78681,GO:0050580,"Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.","2,5-didehydrogluconate reductase activity",molecular_function
78682,GO:0050581,Catalysis of the reaction: mannitol + O2 = mannose + H2O2.,D-mannitol oxidase activity,molecular_function
78683,GO:0050582,Catalysis of the reaction: xylitol + O2 = xylose + H2O2. Xylitol (five carbons) and sorbitol (6 carbons) are the preferred substrates.,xylitol oxidase activity,molecular_function
78684,GO:0050583,Catalysis of the reaction: NADP+ + H2 = NADPH + H+.,hydrogen dehydrogenase (NADP+) activity,molecular_function
78685,GO:0050584,"Catalysis of the reaction: linoleate + O2 = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.",linoleate 11-lipoxygenase activity,molecular_function
78686,GO:0050585,Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.,4-hydroxymandelate synthase activity,molecular_function
78687,GO:0050586,Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H+ + O2 = N-acetylanthranilate + CO.,"3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity",molecular_function
78688,GO:0050587,Catalysis of the reaction: chloride + O2 = chlorite.,chlorite O2-lyase activity,molecular_function
78689,GO:0050588,"Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.","apo-beta-carotenoid-14',13'-dioxygenase activity",molecular_function
78690,GO:0050589,Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.,leucocyanidin oxygenase activity,molecular_function
78691,GO:0050590,Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.,desacetoxyvindoline 4-hydroxylase activity,molecular_function
78692,GO:0050591,Catalysis of the reaction: H+ + NADPH + O2 + quinine = 3-hydroxyquinine + H2O + NADP+.,quinine 3-monooxygenase activity,molecular_function
78693,GO:0050592,Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H+ + NADPH + O2 = (S)-4-hydroxymandelonitrile + 2 H2O + NADP+.,4-hydroxyphenylacetaldehyde oxime monooxygenase activity,molecular_function
78694,GO:0050593,Catalysis of the reaction: (S)-N-methylcoclaurine + H+ + NADPH + O2 = (S)-3'-hydroxy-N-methylcoclaurine + H2O + NADP+.,N-methylcoclaurine 3'-monooxygenase activity,molecular_function
78695,GO:0050594,Catalysis of the reaction: H+ + NADPH + O2 + tabersonine = 16-hydroxytabersonine + H2O + NADP+.,tabersonine 16-hydroxylase activity,molecular_function
78696,GO:0050595,Catalysis of the reaction: 7-deoxyloganin + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganin + oxidized [NADPH-hemoprotein reductase].,7-deoxyloganin 7-hydroxylase activity,molecular_function
78697,GO:0050596,Catalysis of the reaction: H+ + NADPH + O2 + vinorine = H2O + NADP+ + vomilenine.,vinorine hydroxylase activity,molecular_function
78698,GO:0050597,"Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP+.",taxane 10-beta-hydroxylase activity,molecular_function
78699,GO:0050598,"Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-ol = H2O + NADP+ + taxa-4(20),11-dien-5alpha,13alpha-diol.",taxane 13-alpha-hydroxylase activity,molecular_function
78700,GO:0050599,Catalysis of the reaction: 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate.,deacetoxycephalosporin-C synthase activity,molecular_function
78701,GO:0050600,"Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11E)-delta11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-CoA 11-(E)-desaturase activity,molecular_function
78702,GO:0050603,Catalysis of the reaction: AH(2) + O2 + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H+.,thiophene-2-carbonyl-CoA monooxygenase activity,molecular_function
78703,GO:0050604,"Catalysis of the reaction: AH2 + O2 + taxa-4,11-diene = A + H2O + taxa-4(20),11-dien-5alpha-ol.",taxadiene 5-alpha-hydroxylase activity,molecular_function
78704,GO:0050605,Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.,superoxide reductase activity,molecular_function
78705,GO:0050606,"Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP+ = 2-oxo-2H-pyran-4,6-dicarboxylate + H+ + NADPH.",4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity,molecular_function
78706,GO:0050607,Catalysis of the reaction: S-(hydroxymethyl)mycothiol + NAD+ = S-formylmycothiol + NADH + H+.,S-(hydroxymethyl)mycothiol dehydrogenase activity,molecular_function
78707,GO:0050608,Catalysis of the reaction: H2O + NAD+ + vanillin = 2 H+ + NADH + vanillate.,vanillin dehydrogenase (NAD+) activity,molecular_function
78708,GO:0050609,Catalysis of the reaction: H2O + NAD+ + phosphonate = 2 H+ + NADH + phosphate.,phosphonate dehydrogenase activity,molecular_function
78709,GO:0050610,Catalysis of the reaction: 2 glutathione + H+ + methylarsonate = glutathione disulfide + H2O + methylarsonous acid.,methylarsonate reductase activity,molecular_function
78710,GO:0050611,Catalysis of the reaction: H2O + arsenite + 2 oxidized azurin = 2 H+ + 2 reduced azurin + arsenate.,arsenate reductase (azurin) activity,molecular_function
78711,GO:0050613,"Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.",Delta14-sterol reductase activity,molecular_function
78712,GO:0050614,"Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.",Delta24-sterol reductase activity,molecular_function
78713,GO:0050615,"Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + H+ + NADPH.","1,2-dihydrovomilenine reductase activity",molecular_function
78714,GO:0050616,Catalysis of the reaction: loganin + reduced [NADPH--hemoprotein reductase] + O2 = secologanin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+.,secologanin synthase activity,molecular_function
78715,GO:0050617,"Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.","15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity",molecular_function
78716,GO:0050618,"Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.",phycoerythrobilin:ferredoxin oxidoreductase activity,molecular_function
78717,GO:0050619,Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.,phytochromobilin:ferredoxin oxidoreductase activity,molecular_function
78718,GO:0050620,Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.,phycocyanobilin:ferredoxin oxidoreductase activity,molecular_function
78719,GO:0050621,"Catalysis of the reaction: L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2 + H+.","tryptophan alpha,beta-oxidase activity",molecular_function
78720,GO:0050622,Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.,glycine dehydrogenase (cyanide-forming) activity,molecular_function
78721,GO:0050623,Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + H+ + 2 NADPH.,berberine reductase activity,molecular_function
78722,GO:0050624,"Catalysis of the reaction: 1,2-dihydrovomilenine + NADP+ = H+ + NADPH + vomilenine.",vomilenine reductase activity,molecular_function
78723,GO:0050625,"Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H+ + NADH = benzene-1,2,4-triol + NAD+.","2-hydroxy-1,4-benzoquinone reductase (NADH) activity",molecular_function
78724,GO:0050626,Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.,trimethylamine-N-oxide reductase (cytochrome c) activity,molecular_function
78725,GO:0050627,Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.,mycothione reductase [NAD(P)H] activity,molecular_function
78726,GO:0050628,Catalysis of the reaction: acetoacetate + coenzyme M + NADP+ = 2-oxopropyl-coenzyme M + CO2 + NADPH.,2-oxopropyl-CoM reductase (carboxylating) activity,molecular_function
78727,GO:0050629,Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor. The reaction occurs in the reverse direction.,tetrachloroethene reductive dehalogenase activity,molecular_function
78728,GO:0050630,Catalysis of the reaction: (E)-isoeugenol + S-adenosyl-L-methionine = (E)-isomethyleugenol + H+ + S-adenosyl-L-homocysteine.,(iso)eugenol O-methyltransferase activity,molecular_function
78729,GO:0050631,Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP+.,corydaline synthase activity,molecular_function
78730,GO:0050632,"Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.",propionyl-CoA C2-trimethyltridecanoyltransferase activity,molecular_function
78731,GO:0050633,Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.,acetyl-CoA C-myristoyltransferase activity,molecular_function
78732,GO:0050634,"Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.",phloroisovalerophenone synthase activity,molecular_function
78733,GO:0050635,"Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H+ + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O.",acridone synthase activity,molecular_function
78734,GO:0050636,Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.,vinorine synthase activity,molecular_function
78735,GO:0050637,Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+.,lovastatin nonaketide synthase activity,molecular_function
78736,GO:0050638,"Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.",taxadien-5-alpha-ol O-acetyltransferase activity,molecular_function
78737,GO:0050639,Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.,10-hydroxytaxane O-acetyltransferase activity,molecular_function
78738,GO:0050640,Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminoadipate.,isopenicillin-N N-acyltransferase activity,molecular_function
78739,GO:0050641,Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+.,6-methylsalicylic acid synthase activity,molecular_function
78740,GO:0050642,Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.,2-alpha-hydroxytaxane 2-O-benzoyltransferase activity,molecular_function
78741,GO:0050643,Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.,10-deacetylbaccatin III 10-O-acetyltransferase activity,molecular_function
78742,GO:0050644,Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H+ + UDP.,cis-p-coumarate glucosyltransferase activity,molecular_function
78743,GO:0050645,Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.,limonoid glucosyltransferase activity,molecular_function
78744,GO:0050646,"Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.","5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding",molecular_function
78745,GO:0050647,"Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.","5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding",molecular_function
78746,GO:0050648,"Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.","5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding",molecular_function
78747,GO:0050649,"Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 6beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",testosterone 6-beta-hydroxylase activity,molecular_function
78748,GO:0050650,"The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycans, which consist of a core protein linked to a chondroitin sulfate glycosaminoglycan. The chondroitin sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-glucuronic acid-beta-(1,3)-N-acetyl-D-galactosamine, the latter of which can be O-sulfated. Chondroitin sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide ...",chondroitin sulfate proteoglycan biosynthetic process,biological_process
78749,GO:0050651,"The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. Tthe former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated. Dermatan sulfate chains are covalently linked to serin...",dermatan sulfate proteoglycan biosynthetic process,biological_process
78750,GO:0050654,"The chemical reactions and pathways involving chondroitin sulfate proteoglycans, which consist of a core protein linked to a chondroitin sulfate glycosaminoglycan. The chondroitin sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-glucuronic acid-beta-(1,3)-N-acetyl-D-galactosamine, the latter of which can be O-sulfated.",chondroitin sulfate proteoglycan metabolic process,biological_process
78751,GO:0050655,"The chemical reactions and pathways involving dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. The former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated.",dermatan sulfate proteoglycan metabolic process,biological_process
78752,GO:0050656,"Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.",3'-phosphoadenosine 5'-phosphosulfate binding,molecular_function
78753,GO:0050657,"The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nucleic acid transport,biological_process
78754,GO:0050658,"The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",RNA transport,biological_process
78755,GO:0050659,"Catalysis of the reactions: n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate = n adenosine 3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H+, and n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate = n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H+.",N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,molecular_function
78756,GO:0050660,"Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.",flavin adenine dinucleotide binding,molecular_function
78757,GO:0050661,"Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.",NADP binding,molecular_function
78758,GO:0050664,Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.,"oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor",molecular_function
78759,GO:0050665,"The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.",hydrogen peroxide biosynthetic process,biological_process
78760,GO:0050667,"The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.",homocysteine metabolic process,biological_process
78761,GO:0050670,"Any process that modulates the frequency, rate or extent of lymphocyte proliferation.",regulation of lymphocyte proliferation,biological_process
78762,GO:0050671,Any process that activates or increases the rate or extent of lymphocyte proliferation.,positive regulation of lymphocyte proliferation,biological_process
78763,GO:0050672,"Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.",negative regulation of lymphocyte proliferation,biological_process
78764,GO:0050673,"The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.",epithelial cell proliferation,biological_process
78765,GO:0050674,"The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.",urothelial cell proliferation,biological_process
78766,GO:0050675,"Any process that modulates the frequency, rate or extent of urothelial cell proliferation.",regulation of urothelial cell proliferation,biological_process
78767,GO:0050676,"Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.",negative regulation of urothelial cell proliferation,biological_process
78768,GO:0050677,Any process that activates or increases the rate or extent of urothelial cell proliferation.,positive regulation of urothelial cell proliferation,biological_process
78769,GO:0050678,"Any process that modulates the frequency, rate or extent of epithelial cell proliferation.",regulation of epithelial cell proliferation,biological_process
78770,GO:0050679,Any process that activates or increases the rate or extent of epithelial cell proliferation.,positive regulation of epithelial cell proliferation,biological_process
78771,GO:0050680,"Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.",negative regulation of epithelial cell proliferation,biological_process
78772,GO:0050681,Binding to a nuclear androgen receptor.,nuclear androgen receptor binding,molecular_function
78773,GO:0050682,"Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.",AF-2 domain binding,molecular_function
78774,GO:0050683,"Binding to an AF-1 protein domain, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.",AF-1 domain binding,molecular_function
78775,GO:0050684,"Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.",regulation of mRNA processing,biological_process
78776,GO:0050685,"Any process that activates or increases the frequency, rate or extent of mRNA processing.",positive regulation of mRNA processing,biological_process
78777,GO:0050686,"Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.",negative regulation of mRNA processing,biological_process
78778,GO:0050687,"Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.",negative regulation of defense response to virus,biological_process
78779,GO:0050688,"Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.",regulation of defense response to virus,biological_process
78780,GO:0050689,"Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of defense response to virus by host,biological_process
78781,GO:0050691,"Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.",regulation of defense response to virus by host,biological_process
78782,GO:0050692,Binding to a protein's DNA binding domain (DBD).,DNA binding domain binding,molecular_function
78783,GO:0050693,"Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.",LBD domain binding,molecular_function
78784,GO:0050694,"Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.",galactose 3-O-sulfotransferase activity,molecular_function
78785,GO:0050695,Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.,benzoylformate decarboxylase activity,molecular_function
78786,GO:0050696,"The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.",trichloroethylene catabolic process,biological_process
78787,GO:0050697,"Catalysis of the reaction: AH2 + trichloroethene = (Z)-1,2-dichloroethene + A + chloride + H+.",trichloroethene reductive dehalogenase activity,molecular_function
78788,GO:0050698,"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.",proteoglycan sulfotransferase activity,molecular_function
78789,GO:0050699,"Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.",WW domain binding,molecular_function
78790,GO:0050700,"Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing protein...",CARD domain binding,molecular_function
78791,GO:0050708,"Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.",regulation of protein secretion,biological_process
78792,GO:0050709,"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.",negative regulation of protein secretion,biological_process
78793,GO:0050714,"Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.",positive regulation of protein secretion,biological_process
78794,GO:0050727,"Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.",regulation of inflammatory response,biological_process
78795,GO:0050728,"Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.",negative regulation of inflammatory response,biological_process
78796,GO:0050729,"Any process that activates or increases the frequency, rate or extent of the inflammatory response.",positive regulation of inflammatory response,biological_process
78797,GO:0050730,"Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.",regulation of peptidyl-tyrosine phosphorylation,biological_process
78798,GO:0050731,"Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.",positive regulation of peptidyl-tyrosine phosphorylation,biological_process
78799,GO:0050732,"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.",negative regulation of peptidyl-tyrosine phosphorylation,biological_process
78800,GO:0050733,"Binding to an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.",RS domain binding,molecular_function
78801,GO:0050734,Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.,hydroxycinnamoyltransferase activity,molecular_function
78802,GO:0050735,Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.,N-malonyltransferase activity,molecular_function
78803,GO:0050736,Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.,O-malonyltransferase activity,molecular_function
78804,GO:0050737,Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.,O-hydroxycinnamoyltransferase activity,molecular_function
78805,GO:0050738,"Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.",fructosyltransferase activity,molecular_function
78806,GO:0050746,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.",regulation of lipoprotein metabolic process,biological_process
78807,GO:0050747,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.",positive regulation of lipoprotein metabolic process,biological_process
78808,GO:0050748,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.",negative regulation of lipoprotein metabolic process,biological_process
78809,GO:0050750,Binding to a low-density lipoprotein receptor.,low-density lipoprotein particle receptor binding,molecular_function
78810,GO:0050761,"The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.",depsipeptide metabolic process,biological_process
78811,GO:0050762,"The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.",depsipeptide catabolic process,biological_process
78812,GO:0050763,"The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.",depsipeptide biosynthetic process,biological_process
78813,GO:0050764,"Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.",regulation of phagocytosis,biological_process
78814,GO:0050765,"Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.",negative regulation of phagocytosis,biological_process
78815,GO:0050766,"Any process that activates or increases the frequency, rate or extent of phagocytosis.",positive regulation of phagocytosis,biological_process
78816,GO:0050767,"Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.",regulation of neurogenesis,biological_process
78817,GO:0050768,"Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.",negative regulation of neurogenesis,biological_process
78818,GO:0050769,"Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.",positive regulation of neurogenesis,biological_process
78819,GO:0050770,"Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.",regulation of axonogenesis,biological_process
78820,GO:0050771,"Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.",negative regulation of axonogenesis,biological_process
78821,GO:0050772,"Any process that activates or increases the frequency, rate or extent of axonogenesis.",positive regulation of axonogenesis,biological_process
78822,GO:0050773,"Any process that modulates the frequency, rate or extent of dendrite development.",regulation of dendrite development,biological_process
78823,GO:0050774,"Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.",negative regulation of dendrite morphogenesis,biological_process
78824,GO:0050775,"Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.",positive regulation of dendrite morphogenesis,biological_process
78825,GO:0050776,"Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.",regulation of immune response,biological_process
78826,GO:0050777,"Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.",negative regulation of immune response,biological_process
78827,GO:0050778,"Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.",positive regulation of immune response,biological_process
78828,GO:0050779,"Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.",RNA destabilization,biological_process
78829,GO:0050780,Binding to a dopamine receptor.,dopamine receptor binding,molecular_function
78830,GO:0050781,"Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.",ortho-trichlorophenol reductive dehalogenase activity,molecular_function
78831,GO:0050782,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).,galactose uniporter activity,molecular_function
78832,GO:0050784,"The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.",cocaine catabolic process,biological_process
78833,GO:0050785,Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).,advanced glycation end-product receptor activity,molecular_function
78834,GO:0050786,"Binding to a RAGE receptor, the receptor for advanced glycation end-products.",RAGE receptor binding,molecular_function
78835,GO:0050787,Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).,detoxification of mercury ion,biological_process
78836,GO:0050789,"Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.",regulation of biological process,biological_process
78837,GO:0050790,Any process that modulates the activity of an enzyme.,regulation of catalytic activity,biological_process
78838,GO:0050792,"Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.",regulation of viral process,biological_process
78839,GO:0050793,"Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",regulation of developmental process,biological_process
78840,GO:0050794,"Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",regulation of cellular process,biological_process
78841,GO:0050795,"Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.",regulation of behavior,biological_process
78842,GO:0050796,"Any process that modulates the frequency, rate or extent of the regulated release of insulin.",regulation of insulin secretion,biological_process
78843,GO:0050797,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.",thymidylate synthase (FAD) activity,molecular_function
78844,GO:0050798,The expansion of a T cell population following activation by an antigenic stimulus.,activated T cell proliferation,biological_process
78845,GO:0050799,"The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.",cocaine biosynthetic process,biological_process
78846,GO:0050801,Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.,monoatomic ion homeostasis,biological_process
78847,GO:0050802,The part of the circadian sleep/wake cycle where the organism is asleep.,"circadian sleep/wake cycle, sleep",biological_process
78848,GO:0050803,"Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).",regulation of synapse structure or activity,biological_process
78849,GO:0050804,"Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.",modulation of chemical synaptic transmission,biological_process
78850,GO:0050805,"Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.",negative regulation of synaptic transmission,biological_process
78851,GO:0050806,"Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.",positive regulation of synaptic transmission,biological_process
78852,GO:0050807,"Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).",regulation of synapse organization,biological_process
78853,GO:0050808,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).",synapse organization,biological_process
78854,GO:0050809,"Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.",diazepam binding,molecular_function
78855,GO:0050810,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.",regulation of steroid biosynthetic process,biological_process
78856,GO:0050811,"Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.",GABA receptor binding,molecular_function
78857,GO:0050812,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.",regulation of acyl-CoA biosynthetic process,biological_process
78858,GO:0050814,"The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.",epothilone biosynthetic process,biological_process
78859,GO:0050815,Binding to a phosphorylated serine residue within a protein.,phosphoserine residue binding,molecular_function
78860,GO:0050816,Binding to a phosphorylated threonine residue within a protein.,phosphothreonine residue binding,molecular_function
78861,GO:0050817,"The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.",coagulation,biological_process
78862,GO:0050818,"Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.",regulation of coagulation,biological_process
78863,GO:0050819,"Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.",negative regulation of coagulation,biological_process
78864,GO:0050820,"Any process that activates or increases the frequency, rate or extent of coagulation.",positive regulation of coagulation,biological_process
78865,GO:0050821,Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.,protein stabilization,biological_process
78866,GO:0050822,Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.,peptide stabilization,biological_process
78867,GO:0050823,Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.,peptide antigen stabilization,biological_process
78868,GO:0050825,"Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.",ice binding,molecular_function
78869,GO:0050826,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.",response to freezing,biological_process
78870,GO:0050829,Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.,defense response to Gram-negative bacterium,biological_process
78871,GO:0050830,Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.,defense response to Gram-positive bacterium,biological_process
78872,GO:0050831,"A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.",male-specific defense response to bacterium,biological_process
78873,GO:0050832,Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.,defense response to fungus,biological_process
78874,GO:0050833,"Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.",pyruvate transmembrane transporter activity,molecular_function
78875,GO:0050839,Binding to a cell adhesion molecule.,cell adhesion molecule binding,molecular_function
78876,GO:0050840,Binding to a component of the extracellular matrix.,extracellular matrix binding,molecular_function
78877,GO:0050843,"The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.",S-adenosylmethionine catabolic process,biological_process
78878,GO:0050845,"The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.",teichuronic acid biosynthetic process,biological_process
78879,GO:0050847,"A nuclear receptor-mediated signaling pathway initiated by a progesterone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",progesterone receptor signaling pathway,biological_process
78880,GO:0050848,"Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.",regulation of calcium-mediated signaling,biological_process
78881,GO:0050849,"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.",negative regulation of calcium-mediated signaling,biological_process
78882,GO:0050850,"Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.",positive regulation of calcium-mediated signaling,biological_process
78883,GO:0050851,The series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.,antigen receptor-mediated signaling pathway,biological_process
78884,GO:0050852,The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.,T cell receptor signaling pathway,biological_process
78885,GO:0050853,The series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.,B cell receptor signaling pathway,biological_process
78886,GO:0050854,"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.",regulation of antigen receptor-mediated signaling pathway,biological_process
78887,GO:0050855,"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.",regulation of B cell receptor signaling pathway,biological_process
78888,GO:0050856,"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.",regulation of T cell receptor signaling pathway,biological_process
78889,GO:0050857,"Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.",positive regulation of antigen receptor-mediated signaling pathway,biological_process
78890,GO:0050858,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.",negative regulation of antigen receptor-mediated signaling pathway,biological_process
78891,GO:0050859,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.",negative regulation of B cell receptor signaling pathway,biological_process
78892,GO:0050860,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.",negative regulation of T cell receptor signaling pathway,biological_process
78893,GO:0050861,"Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.",positive regulation of B cell receptor signaling pathway,biological_process
78894,GO:0050862,"Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.",positive regulation of T cell receptor signaling pathway,biological_process
78895,GO:0050863,"Any process that modulates the frequency, rate or extent of T cell activation.",regulation of T cell activation,biological_process
78896,GO:0050864,"Any process that modulates the frequency, rate or extent of B cell activation.",regulation of B cell activation,biological_process
78897,GO:0050865,"Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.",regulation of cell activation,biological_process
78898,GO:0050866,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.",negative regulation of cell activation,biological_process
78899,GO:0050867,"Any process that activates or increases the frequency, rate or extent of activation.",positive regulation of cell activation,biological_process
78900,GO:0050868,"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.",negative regulation of T cell activation,biological_process
78901,GO:0050869,"Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.",negative regulation of B cell activation,biological_process
78902,GO:0050870,"Any process that activates or increases the frequency, rate or extent of T cell activation.",positive regulation of T cell activation,biological_process
78903,GO:0050871,"Any process that activates or increases the frequency, rate or extent of B cell activation.",positive regulation of B cell activation,biological_process
78904,GO:0050872,"The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.",white fat cell differentiation,biological_process
78905,GO:0050873,"The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.",brown fat cell differentiation,biological_process
78906,GO:0050877,An organ system process carried out by any of the organs or tissues of the neurological system.,nervous system process,biological_process
78907,GO:0050878,Any process that modulates the levels of body fluids.,regulation of body fluid levels,biological_process
78908,GO:0050879,Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.,multicellular organismal movement,biological_process
78909,GO:0050881,"The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.",musculoskeletal movement,biological_process
78910,GO:0050882,"The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.",voluntary musculoskeletal movement,biological_process
78911,GO:0050883,Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.,"musculoskeletal movement, spinal reflex action",biological_process
78912,GO:0050884,"Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.",neuromuscular process controlling posture,biological_process
78913,GO:0050885,"Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.",neuromuscular process controlling balance,biological_process
78914,GO:0050886,The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.,endocrine process,biological_process
78915,GO:0050887,"The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.",determination of sensory modality,biological_process
78916,GO:0050888,"The determination of where on the body surface, within the body or in the environment a stimulus originates.",determination of stimulus location,biological_process
78917,GO:0050889,The determination of the perceived strength of a sensory stimulus.,determination of stimulus intensity,biological_process
78918,GO:0050890,"The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.",cognition,biological_process
78919,GO:0050891,"A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.",multicellular organismal-level water homeostasis,biological_process
78920,GO:0050892,A process in which nutrients are taken up from the contents of the intestine.,intestinal absorption,biological_process
78921,GO:0050893,"Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.",sensory processing,biological_process
78922,GO:0050894,Any process in which an emotional response is associated with a particular sensory stimulation.,determination of affect,biological_process
78923,GO:0050896,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.",response to stimulus,biological_process
78924,GO:0050897,Binding to a cobalt ion (Co2+).,cobalt ion binding,molecular_function
78925,GO:0050898,"The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.",nitrile metabolic process,biological_process
78926,GO:0050899,"The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.",nitrile catabolic process,biological_process
78927,GO:0050900,The movement of a leukocyte within or between different tissues and organs of the body.,leukocyte migration,biological_process
78928,GO:0050901,"Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissu...",leukocyte tethering or rolling,biological_process
78929,GO:0050902,"The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.",leukocyte adhesive activation,biological_process
78930,GO:0050903,"The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.",leukocyte activation-dependent arrest,biological_process
78931,GO:0050904,"The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.",diapedesis,biological_process
78932,GO:0050905,Any process pertaining to the functions of the nervous and muscular systems of an organism.,neuromuscular process,biological_process
78933,GO:0050906,The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.,detection of stimulus involved in sensory perception,biological_process
78934,GO:0050907,The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.,detection of chemical stimulus involved in sensory perception,biological_process
78935,GO:0050908,The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.,detection of light stimulus involved in visual perception,biological_process
78936,GO:0050909,"The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.",sensory perception of taste,biological_process
78937,GO:0050910,The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.,detection of mechanical stimulus involved in sensory perception of sound,biological_process
78938,GO:0050911,The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.,detection of chemical stimulus involved in sensory perception of smell,biological_process
78939,GO:0050912,The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.,detection of chemical stimulus involved in sensory perception of taste,biological_process
78940,GO:0050913,"The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of bitter taste,biological_process
78941,GO:0050914,"The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of salty taste,biological_process
78942,GO:0050915,"The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of sour taste,biological_process
78943,GO:0050916,"The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of sweet taste,biological_process
78944,GO:0050917,"The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.",sensory perception of umami taste,biological_process
78945,GO:0050918,The directed movement of a motile cell or organism towards a higher concentration of a chemical.,positive chemotaxis,biological_process
78946,GO:0050919,The directed movement of a motile cell or organism towards a lower concentration of a chemical.,negative chemotaxis,biological_process
78947,GO:0050920,"Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.",regulation of chemotaxis,biological_process
78948,GO:0050921,"Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.",positive regulation of chemotaxis,biological_process
78949,GO:0050922,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.",negative regulation of chemotaxis,biological_process
78950,GO:0050923,"Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.",regulation of negative chemotaxis,biological_process
78951,GO:0050924,"Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.",positive regulation of negative chemotaxis,biological_process
78952,GO:0050925,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.",negative regulation of negative chemotaxis,biological_process
78953,GO:0050926,"Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.",regulation of positive chemotaxis,biological_process
78954,GO:0050927,"Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.",positive regulation of positive chemotaxis,biological_process
78955,GO:0050928,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.",negative regulation of positive chemotaxis,biological_process
78956,GO:0050929,Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.,induction of negative chemotaxis,biological_process
78957,GO:0050930,Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.,induction of positive chemotaxis,biological_process
78958,GO:0050931,"The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.",pigment cell differentiation,biological_process
78959,GO:0050932,"Any process that modulates the frequency, rate or extent of pigmented cell differentiation.",regulation of pigment cell differentiation,biological_process
78960,GO:0050933,"The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).",early stripe melanocyte differentiation,biological_process
78961,GO:0050934,"The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).",late stripe melanocyte differentiation,biological_process
78962,GO:0050935,"The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.",iridophore differentiation,biological_process
78963,GO:0050936,The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.,xanthophore differentiation,biological_process
78964,GO:0050937,"Any process that modulates the frequency, rate or extent of iridophore differentiation.",regulation of iridophore differentiation,biological_process
78965,GO:0050938,"Any process that modulates the frequency, rate or extent of xanthophore differentiation.",regulation of xanthophore differentiation,biological_process
78966,GO:0050939,"Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.",regulation of early stripe melanocyte differentiation,biological_process
78967,GO:0050940,"Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.",regulation of late stripe melanocyte differentiation,biological_process
78968,GO:0050941,"Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.",negative regulation of pigment cell differentiation,biological_process
78969,GO:0050942,"Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.",positive regulation of pigment cell differentiation,biological_process
78970,GO:0050943,"Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.",negative regulation of iridophore differentiation,biological_process
78971,GO:0050944,"Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.",negative regulation of xanthophore differentiation,biological_process
78972,GO:0050945,"Any process that activates or increases the frequency, rate or extent of iridophore differentiation.",positive regulation of iridophore differentiation,biological_process
78973,GO:0050946,"Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.",positive regulation of xanthophore differentiation,biological_process
78974,GO:0050947,"Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.",negative regulation of early stripe melanocyte differentiation,biological_process
78975,GO:0050948,"Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.",positive regulation of early stripe melanocyte differentiation,biological_process
78976,GO:0050949,"Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.",negative regulation of late stripe melanocyte differentiation,biological_process
78977,GO:0050950,"Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.",positive regulation of late stripe melanocyte differentiation,biological_process
78978,GO:0050951,"The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of temperature stimulus,biological_process
78979,GO:0050952,"The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of electrical stimulus,biological_process
78980,GO:0050953,"The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of light stimulus,biological_process
78981,GO:0050954,"The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of mechanical stimulus,biological_process
78982,GO:0050955,"The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).",thermoception,biological_process
78983,GO:0050956,"The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.",electroception,biological_process
78984,GO:0050957,"The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism ...",equilibrioception,biological_process
78985,GO:0050958,"The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.",magnetoreception,biological_process
78986,GO:0050959,"Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.",echolocation,biological_process
78987,GO:0050960,The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.,detection of temperature stimulus involved in thermoception,biological_process
78988,GO:0050961,The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.,detection of temperature stimulus involved in sensory perception,biological_process
78989,GO:0050962,The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.,detection of light stimulus involved in sensory perception,biological_process
78990,GO:0050965,The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.,detection of temperature stimulus involved in sensory perception of pain,biological_process
78991,GO:0050966,The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.,detection of mechanical stimulus involved in sensory perception of pain,biological_process
78992,GO:0050968,The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.,detection of chemical stimulus involved in sensory perception of pain,biological_process
78993,GO:0050973,"The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.",detection of mechanical stimulus involved in equilibrioception,biological_process
78994,GO:0050974,The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.,detection of mechanical stimulus involved in sensory perception,biological_process
78995,GO:0050975,"The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be...",sensory perception of touch,biological_process
78996,GO:0050976,The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.,detection of mechanical stimulus involved in sensory perception of touch,biological_process
78997,GO:0050977,"The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The...",magnetoreception by sensory perception of chemical stimulus,biological_process
78998,GO:0050978,"The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.",magnetoreception by sensory perception of electrical stimulus,biological_process
78999,GO:0050979,"The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.",magnetoreception by sensory perception of mechanical stimulus,biological_process
79000,GO:0050980,The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.,detection of light stimulus involved in magnetoreception,biological_process
79001,GO:0050981,The series of events by which an electrical stimulus is received and converted into a molecular signal.,detection of electrical stimulus,biological_process
79002,GO:0050982,The series of events by which a mechanical stimulus is received and converted into a molecular signal.,detection of mechanical stimulus,biological_process
79003,GO:0050989,The carboxylation of the N-terminal amino acid of proteins.,N-terminal protein amino acid carboxylation,biological_process
79004,GO:0050990,The carbamoylation of the N-terminal amino acid of proteins.,N-terminal protein amino acid carbamoylation,biological_process
79005,GO:0050992,The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.,dimethylallyl diphosphate biosynthetic process,biological_process
79006,GO:0050993,The chemical reactions and pathways involving dimethylallyl diphosphate.,dimethylallyl diphosphate metabolic process,biological_process
79007,GO:0050994,"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.",regulation of lipid catabolic process,biological_process
79008,GO:0050995,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.",negative regulation of lipid catabolic process,biological_process
79009,GO:0050996,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.",positive regulation of lipid catabolic process,biological_process
79010,GO:0050997,"Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.",quaternary ammonium group binding,molecular_function
79011,GO:0050998,Binding to nitric-oxide synthase.,nitric-oxide synthase binding,molecular_function
79012,GO:0050999,Any process that modulates the activity of the enzyme nitric-oxide synthase.,regulation of nitric-oxide synthase activity,biological_process
79013,GO:0051000,Any process that activates or increases the activity of the enzyme nitric-oxide synthase.,positive regulation of nitric-oxide synthase activity,biological_process
79014,GO:0051001,Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.,negative regulation of nitric-oxide synthase activity,biological_process
79015,GO:0051002,"Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","ligase activity, forming nitrogen-metal bonds",molecular_function
79016,GO:0051003,"Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.","ligase activity, forming nitrogen-metal bonds, forming coordination complexes",molecular_function
79017,GO:0051005,Any process that stops or reduces the activity of the enzyme lipoprotein lipase.,negative regulation of lipoprotein lipase activity,biological_process
79018,GO:0051006,Any process that activates or increases the activity of the enzyme lipoprotein lipase.,positive regulation of lipoprotein lipase activity,biological_process
79019,GO:0051007,Catalysis of the reaction: squalene = hop-22(29)-ene.,squalene-hopene cyclase activity,molecular_function
79020,GO:0051008,"Binding to Hsp27 proteins, a lightweight heat shock protein.",Hsp27 protein binding,molecular_function
79021,GO:0051009,Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.,O-acetylhomoserine sulfhydrylase activity,molecular_function
79022,GO:0051010,Binding to the plus end of a microtubule.,microtubule plus-end binding,molecular_function
79023,GO:0051011,Binding to the minus end of a microtubule.,microtubule minus-end binding,molecular_function
79024,GO:0051012,The movement of one microtubule along another microtubule.,microtubule sliding,biological_process
79025,GO:0051013,"The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.",microtubule severing,biological_process
79026,GO:0051014,The process in which an actin filament is broken down into smaller filaments.,actin filament severing,biological_process
79027,GO:0051015,"Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.",actin filament binding,molecular_function
79028,GO:0051016,"The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.",barbed-end actin filament capping,biological_process
79029,GO:0051017,The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.,actin filament bundle assembly,biological_process
79030,GO:0051018,Binding to a protein kinase A.,protein kinase A binding,molecular_function
79031,GO:0051019,Binding to a mitogen-activated protein kinase.,mitogen-activated protein kinase binding,molecular_function
79032,GO:0051020,"Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP.",GTPase binding,molecular_function
79033,GO:0051021,Binding to a GDP-dissociation inhibitor protein.,GDP-dissociation inhibitor binding,molecular_function
79034,GO:0051022,Binding to a Rho GDP-dissociation inhibitor protein.,Rho GDP-dissociation inhibitor binding,molecular_function
79035,GO:0051026,"The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.",chiasma assembly,biological_process
79036,GO:0051027,"The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",DNA transport,biological_process
79037,GO:0051028,"The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",mRNA transport,biological_process
79038,GO:0051029,"The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",rRNA transport,biological_process
79039,GO:0051030,"The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",snRNA transport,biological_process
79040,GO:0051031,"The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tRNA transport,biological_process
79041,GO:0051032,"Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.",nucleic acid transmembrane transporter activity,molecular_function
79042,GO:0051033,"Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.",RNA transmembrane transporter activity,molecular_function
79043,GO:0051034,"Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.",tRNA transmembrane transporter activity,molecular_function
79044,GO:0051035,"Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.",DNA transmembrane transporter activity,molecular_function
79045,GO:0051036,"Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.",regulation of endosome size,biological_process
79046,GO:0051040,"Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.",regulation of calcium-independent cell-cell adhesion,biological_process
79047,GO:0051041,"Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.",positive regulation of calcium-independent cell-cell adhesion,biological_process
79048,GO:0051042,"Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.",negative regulation of calcium-independent cell-cell adhesion,biological_process
79049,GO:0051043,"Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).",regulation of membrane protein ectodomain proteolysis,biological_process
79050,GO:0051044,"Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.",positive regulation of membrane protein ectodomain proteolysis,biological_process
79051,GO:0051045,"Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.",negative regulation of membrane protein ectodomain proteolysis,biological_process
79052,GO:0051046,"Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.",regulation of secretion,biological_process
79053,GO:0051047,"Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.",positive regulation of secretion,biological_process
79054,GO:0051048,"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.",negative regulation of secretion,biological_process
79055,GO:0051049,"Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of transport,biological_process
79056,GO:0051050,"Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of transport,biological_process
79057,GO:0051051,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of transport,biological_process
79058,GO:0051052,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.",regulation of DNA metabolic process,biological_process
79059,GO:0051053,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.",negative regulation of DNA metabolic process,biological_process
79060,GO:0051054,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.",positive regulation of DNA metabolic process,biological_process
79061,GO:0051055,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.",negative regulation of lipid biosynthetic process,biological_process
79062,GO:0051056,"Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.",regulation of small GTPase mediated signal transduction,biological_process
79063,GO:0051057,"Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.",positive regulation of small GTPase mediated signal transduction,biological_process
79064,GO:0051058,"Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.",negative regulation of small GTPase mediated signal transduction,biological_process
79065,GO:0051059,"Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.",NF-kappaB binding,molecular_function
79066,GO:0051060,"Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.",pullulanase activity,molecular_function
79067,GO:0051061,Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.,ADP reductase activity,molecular_function
79068,GO:0051062,Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.,UDP reductase activity,molecular_function
79069,GO:0051063,Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.,CDP reductase activity,molecular_function
79070,GO:0051066,"The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.",dihydrobiopterin metabolic process,biological_process
79071,GO:0051067,"The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.",dihydropteridine metabolic process,biological_process
79072,GO:0051068,"The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.",dihydrolipoamide metabolic process,biological_process
79073,GO:0051069,"The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.",galactomannan metabolic process,biological_process
79074,GO:0051070,"The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.",galactomannan biosynthetic process,biological_process
79075,GO:0051072,"The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.","4,6-pyruvylated galactose residue biosynthetic process",biological_process
79076,GO:0051073,Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.,adenosylcobinamide-GDP ribazoletransferase activity,molecular_function
79077,GO:0051075,"Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.",S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity,molecular_function
79078,GO:0051077,Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.,secondary cell septum,cellular_component
79079,GO:0051078,The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.,meiotic nuclear membrane disassembly,biological_process
79080,GO:0051079,The controlled breakdown of the nuclear membranes during the first division of meiosis.,meiosis I nuclear membrane disassembly,biological_process
79081,GO:0051080,The controlled breakdown of the nuclear membranes during the second division of meiosis.,meiosis II nuclear membrane disassembly,biological_process
79082,GO:0051081,"The controlled breakdown of the nuclear membranes, for example during cellular division.",nuclear membrane disassembly,biological_process
79083,GO:0051083,The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.,'de novo' cotranslational protein folding,biological_process
79084,GO:0051084,The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.,'de novo' post-translational protein folding,biological_process
79085,GO:0051087,"Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.",protein-folding chaperone binding,molecular_function
79086,GO:0051089,"The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.",constitutive protein ectodomain proteolysis,biological_process
79087,GO:0051093,"Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",negative regulation of developmental process,biological_process
79088,GO:0051094,"Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",positive regulation of developmental process,biological_process
79089,GO:0051096,Any process that activates or increases the activity of a helicase.,positive regulation of helicase activity,biological_process
79090,GO:0051097,Any process that stops or reduces the activity of a helicase.,negative regulation of helicase activity,biological_process
79091,GO:0051098,"Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.",regulation of binding,biological_process
79092,GO:0051099,"Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.",positive regulation of binding,biological_process
79093,GO:0051100,"Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.",negative regulation of binding,biological_process
79094,GO:0051101,"Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).",regulation of DNA binding,biological_process
79095,GO:0051108,Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.,carnitine-CoA ligase activity,molecular_function
79096,GO:0051109,Catalysis of the reaction: (R)-carnitine + ATP + CoA = (R)-carnitinyl-CoA + AMP + diphosphate. Also catalyzes the transfer of CoA to crotonobetaine and gamma-butyrobetaine.,crotonobetaine-CoA ligase activity,molecular_function
79097,GO:0051116,"Catalysis of the reaction: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H+ + phosphate.",cobaltochelatase activity,molecular_function
79098,GO:0051117,"Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.",ATPase binding,molecular_function
79099,GO:0051118,"Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.","glucan endo-1,3-alpha-glucosidase activity",molecular_function
79100,GO:0051119,"Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.",sugar transmembrane transporter activity,molecular_function
79101,GO:0051122,"The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.",hepoxilin biosynthetic process,biological_process
79102,GO:0051123,"The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which may include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH complexes). The PIC engages RNA polymerase II on its DNA template strand and sparks polymerization of the first few RNA nucleotides of the nascent transcript, of which 8 are base-paired with the DNA template within a DNA bubble. PIC...",RNA polymerase II preinitiation complex assembly,biological_process
79103,GO:0051124,The assembly of a synapse at a neuromuscular junction.,synaptic assembly at neuromuscular junction,biological_process
79104,GO:0051125,"Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.",regulation of actin nucleation,biological_process
79105,GO:0051126,"Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.",negative regulation of actin nucleation,biological_process
79106,GO:0051127,"Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.",positive regulation of actin nucleation,biological_process
79107,GO:0051128,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.",regulation of cellular component organization,biological_process
79108,GO:0051129,"Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.",negative regulation of cellular component organization,biological_process
79109,GO:0051130,"Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.",positive regulation of cellular component organization,biological_process
79110,GO:0051131,"The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.",chaperone-mediated protein complex assembly,biological_process
79111,GO:0051132,"The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.",NK T cell activation,biological_process
79112,GO:0051133,"Any process that modulates the frequency, rate or extent of natural killer T cell activation.",regulation of NK T cell activation,biological_process
79113,GO:0051134,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.",negative regulation of NK T cell activation,biological_process
79114,GO:0051135,"Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.",positive regulation of NK T cell activation,biological_process
79115,GO:0051136,"Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.",regulation of NK T cell differentiation,biological_process
79116,GO:0051137,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.",negative regulation of NK T cell differentiation,biological_process
79117,GO:0051138,"Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.",positive regulation of NK T cell differentiation,biological_process
79118,GO:0051139,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).,metal cation:proton antiporter activity,molecular_function
79119,GO:0051140,"Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.",regulation of NK T cell proliferation,biological_process
79120,GO:0051141,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.",negative regulation of NK T cell proliferation,biological_process
79121,GO:0051142,"Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.",positive regulation of NK T cell proliferation,biological_process
79122,GO:0051144,"The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.","1,2-propanediol catabolic process",biological_process
79123,GO:0051145,The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.,smooth muscle cell differentiation,biological_process
79124,GO:0051146,"The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.",striated muscle cell differentiation,biological_process
79125,GO:0051147,"Any process that modulates the frequency, rate or extent of muscle cell differentiation.",regulation of muscle cell differentiation,biological_process
79126,GO:0051148,"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.",negative regulation of muscle cell differentiation,biological_process
79127,GO:0051149,"Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.",positive regulation of muscle cell differentiation,biological_process
79128,GO:0051150,"Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.",regulation of smooth muscle cell differentiation,biological_process
79129,GO:0051151,"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.",negative regulation of smooth muscle cell differentiation,biological_process
79130,GO:0051152,"Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.",positive regulation of smooth muscle cell differentiation,biological_process
79131,GO:0051153,"Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.",regulation of striated muscle cell differentiation,biological_process
79132,GO:0051154,"Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.",negative regulation of striated muscle cell differentiation,biological_process
79133,GO:0051155,"Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.",positive regulation of striated muscle cell differentiation,biological_process
79134,GO:0051156,"The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.",glucose 6-phosphate metabolic process,biological_process
79135,GO:0051157,"The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.",arabitol catabolic process,biological_process
79136,GO:0051158,"The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.",L-arabitol catabolic process,biological_process
79137,GO:0051159,"The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.",D-arabitol catabolic process,biological_process
79138,GO:0051160,"The chemical reactions and pathways resulting in the breakdown of xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.",xylitol catabolic process,biological_process
79139,GO:0051164,"The chemical reactions and pathways involving xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.",xylitol metabolic process,biological_process
79140,GO:0051167,"The chemical reactions and pathways involving D-xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.",D-xylulose 5-phosphate metabolic process,biological_process
79141,GO:0051168,The directed movement of substances out of the nucleus.,nuclear export,biological_process
79142,GO:0051169,"The directed movement of substances into, out of, or within the nucleus.",nuclear transport,biological_process
79143,GO:0051170,The directed movement of substances into the nucleus.,import into nucleus,biological_process
79144,GO:0051174,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.",regulation of phosphorus metabolic process,biological_process
79145,GO:0051177,The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.,meiotic sister chromatid cohesion,biological_process
79146,GO:0051179,"Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.",localization,biological_process
79147,GO:0051180,"The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.",vitamin transport,biological_process
79148,GO:0051189,"The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.",prosthetic group metabolic process,biological_process
79149,GO:0051190,"The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.",prosthetic group catabolic process,biological_process
79150,GO:0051191,"The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.",prosthetic group biosynthetic process,biological_process
79151,GO:0051192,"Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.",prosthetic group binding,molecular_function
79152,GO:0051204,The process that results in the incorporation of a protein into a mitochondrial membrane.,protein insertion into mitochondrial membrane,biological_process
79153,GO:0051205,The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.,protein insertion into membrane,biological_process
79154,GO:0051209,"The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.",release of sequestered calcium ion into cytosol,biological_process
79155,GO:0051210,"The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.",isotropic cell growth,biological_process
79156,GO:0051211,"The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.",anisotropic cell growth,biological_process
79157,GO:0051212,Binding to a vanadium ion (V).,vanadium ion binding,molecular_function
79158,GO:0051213,Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate.,dioxygenase activity,molecular_function
79159,GO:0051214,"An RNAi-mediated post-transcriptional gene silencing pathway induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL4 is the primary Dicer to detect RNA viruses.",RNAi-mediated antiviral immunity against RNA virus,biological_process
79160,GO:0051215,"An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses.",RNAi-mediated antiviral immunity against DNA virus,biological_process
79161,GO:0051216,"The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",cartilage development,biological_process
79162,GO:0051219,Binding to a phosphorylated protein.,phosphoprotein binding,molecular_function
79163,GO:0051222,"Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of protein transport,biological_process
79164,GO:0051223,"Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of protein transport,biological_process
79165,GO:0051224,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of protein transport,biological_process
79166,GO:0051225,"The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.",spindle assembly,biological_process
79167,GO:0051228,The controlled breakdown of the spindle during a mitotic cell cycle.,mitotic spindle disassembly,biological_process
79168,GO:0051229,The controlled breakdown of the spindle during a meiotic cell cycle.,meiotic spindle disassembly,biological_process
79169,GO:0051230,"The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.",spindle disassembly,biological_process
79170,GO:0051231,The cell cycle process in which the distance is lengthened between poles of the spindle.,spindle elongation,biological_process
79171,GO:0051232,The lengthening of the distance between poles of the spindle during a meiotic cell cycle.,meiotic spindle elongation,biological_process
79172,GO:0051233,The area in the center of the spindle where the spindle microtubules from opposite poles overlap.,spindle midzone,cellular_component
79173,GO:0051234,"Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.",establishment of localization,biological_process
79174,GO:0051235,"Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.",maintenance of location,biological_process
79175,GO:0051236,The directed movement of RNA to a specific location.,establishment of RNA localization,biological_process
79176,GO:0051237,Any process in which RNA is maintained in a location and prevented from moving elsewhere.,maintenance of RNA location,biological_process
79177,GO:0051239,"Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.",regulation of multicellular organismal process,biological_process
79178,GO:0051240,"Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.",positive regulation of multicellular organismal process,biological_process
79179,GO:0051241,"Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.",negative regulation of multicellular organismal process,biological_process
79180,GO:0051245,"Any process that stops, prevents, or reduces the rate of the cellular defense response.",negative regulation of cellular defense response,biological_process
79181,GO:0051246,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.",regulation of protein metabolic process,biological_process
79182,GO:0051247,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.",positive regulation of protein metabolic process,biological_process
79183,GO:0051248,"Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.",negative regulation of protein metabolic process,biological_process
79184,GO:0051249,"Any process that modulates the frequency, rate or extent of lymphocyte activation.",regulation of lymphocyte activation,biological_process
79185,GO:0051250,"Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.",negative regulation of lymphocyte activation,biological_process
79186,GO:0051251,"Any process that activates or increases the frequency, rate or extent of lymphocyte activation.",positive regulation of lymphocyte activation,biological_process
79187,GO:0051252,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.",regulation of RNA metabolic process,biological_process
79188,GO:0051253,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.",negative regulation of RNA metabolic process,biological_process
79189,GO:0051254,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.",positive regulation of RNA metabolic process,biological_process
79190,GO:0051255,"The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.",spindle midzone assembly,biological_process
79191,GO:0051256,"The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.",mitotic spindle midzone assembly,biological_process
79192,GO:0051257,"The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.",meiotic spindle midzone assembly,biological_process
79193,GO:0051258,"The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.",protein polymerization,biological_process
79194,GO:0051259,"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.",protein complex oligomerization,biological_process
79195,GO:0051260,"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.",protein homooligomerization,biological_process
79196,GO:0051261,"The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.",protein depolymerization,biological_process
79197,GO:0051262,"The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.",protein tetramerization,biological_process
79198,GO:0051264,"Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.",mono-olein transacylation activity,molecular_function
79199,GO:0051265,"Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.",diolein transacylation activity,molecular_function
79200,GO:0051266,Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.,sirohydrochlorin ferrochelatase activity,molecular_function
79201,GO:0051268,"Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.",alpha-keto amide reductase activity,molecular_function
79202,GO:0051269,Catalysis of the reaction: alpha-ketoester + H+ + NADPH = (R)-hydroxy ester + NADP+.,alpha-ketoester reductase (NADP+) activity,molecular_function
79203,GO:0051273,"The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.",beta-glucan metabolic process,biological_process
79204,GO:0051274,The chemical reactions and pathways resulting in the formation of beta-glucans.,beta-glucan biosynthetic process,biological_process
79205,GO:0051275,The chemical reactions and pathways resulting in the breakdown of beta-glucans.,beta-glucan catabolic process,biological_process
79206,GO:0051276,"A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.",chromosome organization,biological_process
79207,GO:0051278,The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.,fungal-type cell wall polysaccharide biosynthetic process,biological_process
79208,GO:0051279,"Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.",regulation of release of sequestered calcium ion into cytosol,biological_process
79209,GO:0051280,"Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.",negative regulation of release of sequestered calcium ion into cytosol,biological_process
79210,GO:0051281,"Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.",positive regulation of release of sequestered calcium ion into cytosol,biological_process
79211,GO:0051285,The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.,cell cortex of cell tip,cellular_component
79212,GO:0051286,The region at the end of the longest axis of a cylindrical or elongated cell.,cell tip,cellular_component
79213,GO:0051287,"Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.",NAD binding,molecular_function
79214,GO:0051289,"The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.",protein homotetramerization,biological_process
79215,GO:0051290,"The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.",protein heterotetramerization,biological_process
79216,GO:0051291,"The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.",protein heterooligomerization,biological_process
79217,GO:0051292,"The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.",nuclear pore complex assembly,biological_process
79218,GO:0051293,The directed movement of the spindle to a specific location in the cell.,establishment of spindle localization,biological_process
79219,GO:0051294,Any process that set the alignment of spindle relative to other cellular structures.,establishment of spindle orientation,biological_process
79220,GO:0051295,The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.,establishment of meiotic spindle localization,biological_process
79221,GO:0051296,Any process that set the alignment of meiotic spindle relative to other cellular structures.,establishment of meiotic spindle orientation,biological_process
79222,GO:0051298,"The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.",centrosome duplication,biological_process
79223,GO:0051299,The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.,centrosome separation,biological_process
79224,GO:0051300,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.",spindle pole body organization,biological_process
79225,GO:0051301,"The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",cell division,biological_process
79226,GO:0051302,"Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.",regulation of cell division,biological_process
79227,GO:0051304,"The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo ...",chromosome separation,biological_process
79228,GO:0051305,"The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.",chromosome movement towards spindle pole,biological_process
79229,GO:0051306,The process in which sister chromatids are physically detached from each other during mitosis.,mitotic sister chromatid separation,biological_process
79230,GO:0051307,The process in which chromosomes are physically detached from each other during meiosis.,meiotic chromosome separation,biological_process
79231,GO:0051308,The process in which paired chromosomes are physically detached from each other during male meiosis.,male meiosis chromosome separation,biological_process
79232,GO:0051309,The process in which paired chromosomes are physically detached from each other during female meiosis.,female meiosis chromosome separation,biological_process
79233,GO:0051310,"A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.",metaphase chromosome alignment,biological_process
79234,GO:0051311,"A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.",meiotic metaphase chromosome alignment,biological_process
79235,GO:0051315,The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.,attachment of mitotic spindle microtubules to kinetochore,biological_process
79236,GO:0051316,The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis.,attachment of meiotic spindle microtubules to kinetochore,biological_process
79237,GO:0051318,The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.,G1 phase,biological_process
79238,GO:0051319,The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).,G2 phase,biological_process
79239,GO:0051320,"The cell cycle phase, following G1, during which DNA synthesis takes place.",S phase,biological_process
79240,GO:0051321,"Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.",meiotic cell cycle,biological_process
79241,GO:0051322,"The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.",anaphase,biological_process
79242,GO:0051323,"The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.",metaphase,biological_process
79243,GO:0051324,The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.,prophase,biological_process
79244,GO:0051325,"The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.",interphase,biological_process
79245,GO:0051326,The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.,telophase,biological_process
79246,GO:0051327,"A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.",meiotic M phase,biological_process
79247,GO:0051328,"The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.",meiotic interphase,biological_process
79248,GO:0051329,"The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.",mitotic interphase,biological_process
79249,GO:0051330,The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.,meiotic G1 phase,biological_process
79250,GO:0051331,The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.,meiotic G2 phase,biological_process
79251,GO:0051332,"The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.",meiotic S phase,biological_process
79252,GO:0051333,The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.,meiotic nuclear membrane reassembly,biological_process
79253,GO:0051334,The reformation of the nuclear membranes during meiosis I.,meiosis I nuclear membrane reassembly,biological_process
79254,GO:0051335,The reformation of the nuclear membrane during meiosis II.,meiosis II nuclear membrane reassembly,biological_process
79255,GO:0051336,"Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.",regulation of hydrolase activity,biological_process
79256,GO:0051337,Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.,amitosis,biological_process
79257,GO:0051338,"Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.",regulation of transferase activity,biological_process
79258,GO:0051341,"Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.",regulation of oxidoreductase activity,biological_process
79259,GO:0051344,"Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.",negative regulation of cyclic-nucleotide phosphodiesterase activity,biological_process
79260,GO:0051345,"Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.",positive regulation of hydrolase activity,biological_process
79261,GO:0051346,"Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.",negative regulation of hydrolase activity,biological_process
79262,GO:0051349,"Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.",positive regulation of lyase activity,biological_process
79263,GO:0051351,"Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.",positive regulation of ligase activity,biological_process
79264,GO:0051353,"Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.",positive regulation of oxidoreductase activity,biological_process
79265,GO:0051354,"Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.",negative regulation of oxidoreductase activity,biological_process
79266,GO:0051355,"The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.",proprioception involved in equilibrioception,biological_process
79267,GO:0051365,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.",cellular response to potassium ion starvation,biological_process
79268,GO:0051366,The modification of a protein amino acid by formation of an ester or amide with decanoic acid.,protein decanoylation,biological_process
79269,GO:0051371,Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.,muscle alpha-actinin binding,molecular_function
79270,GO:0051373,"Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.",FATZ binding,molecular_function
79271,GO:0051377,Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.,mannose-ethanolamine phosphotransferase activity,molecular_function
79272,GO:0051378,"Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.",serotonin binding,molecular_function
79273,GO:0051379,"Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.",epinephrine binding,molecular_function
79274,GO:0051380,"Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.",norepinephrine binding,molecular_function
79275,GO:0051381,"Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine binding,molecular_function
79276,GO:0051382,"The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.",kinetochore assembly,biological_process
79277,GO:0051383,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.",kinetochore organization,biological_process
79278,GO:0051384,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.",response to glucocorticoid,biological_process
79279,GO:0051385,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.",response to mineralocorticoid,biological_process
79280,GO:0051386,"Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.",regulation of neurotrophin TRK receptor signaling pathway,biological_process
79281,GO:0051387,"Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.",negative regulation of neurotrophin TRK receptor signaling pathway,biological_process
79282,GO:0051388,"Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.",positive regulation of neurotrophin TRK receptor signaling pathway,biological_process
79283,GO:0051391,"The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",tRNA acetylation,biological_process
79284,GO:0051392,Catalysis of the reaction: a cytidine in tRNA + acetyl-CoA + ATP + H2O = ADP + an N4-acetylcytidine in tRNA + CoA + H+ + phosphate.,tRNA cytidine N4-acetyltransferase activity,molecular_function
79285,GO:0051393,"Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.",alpha-actinin binding,molecular_function
79286,GO:0051394,"Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.",regulation of nerve growth factor receptor activity,biological_process
79287,GO:0051400,"Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.",BH domain binding,molecular_function
79288,GO:0051401,"Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.",CH domain binding,molecular_function
79289,GO:0051402,"Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.",neuron apoptotic process,biological_process
79290,GO:0051403,A MAPK cascade that starts with the activation of a stress-activated MAP kinase cascade.,stress-activated MAPK cascade,biological_process
79291,GO:0051407,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).,glycerone phosphate:phosphate antiporter activity,molecular_function
79292,GO:0051408,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).,glyceraldehyde 3-phosphate:phosphate antiporter activity,molecular_function
79293,GO:0051409,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.",response to nitrosative stress,biological_process
79294,GO:0051410,Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.,detoxification of nitrogen compound,biological_process
79295,GO:0051412,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.",response to corticosterone,biological_process
79296,GO:0051413,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate ...",response to cortisone,biological_process
79297,GO:0051414,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.",response to cortisol,biological_process
79298,GO:0051415,"The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.",microtubule nucleation by interphase microtubule organizing center,biological_process
79299,GO:0051417,"The 'de novo' formation of a microtubule, mediated by the spindle pole body.",microtubule nucleation by spindle pole body,biological_process
79300,GO:0051418,"The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.",microtubule nucleation by microtubule organizing center,biological_process
79301,GO:0051424,"Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.",corticotropin-releasing hormone binding,molecular_function
79302,GO:0051425,Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain.,PTB domain binding,molecular_function
79303,GO:0051427,Binding to a receptor for a hormone.,hormone receptor binding,molecular_function
79304,GO:0051428,Binding to a receptor for a peptide hormone.,peptide hormone receptor binding,molecular_function
79305,GO:0051429,"Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.",corticotropin-releasing hormone receptor binding,molecular_function
79306,GO:0051430,"Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.",corticotropin-releasing hormone receptor 1 binding,molecular_function
79307,GO:0051431,Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.,corticotropin-releasing hormone receptor 2 binding,molecular_function
79308,GO:0051432,"Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.",BH1 domain binding,molecular_function
79309,GO:0051433,"Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.",BH2 domain binding,molecular_function
79310,GO:0051434,"Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.",BH3 domain binding,molecular_function
79311,GO:0051435,"Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.",BH4 domain binding,molecular_function
79312,GO:0051438,"Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.",regulation of ubiquitin-protein transferase activity,biological_process
79313,GO:0051443,"Any process that activates, maintains or increases the rate of ubiquitin transferase activity.",positive regulation of ubiquitin-protein transferase activity,biological_process
79314,GO:0051444,"Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.",negative regulation of ubiquitin-protein transferase activity,biological_process
79315,GO:0051445,Any process that modulates the rate or extent of progression through the meiotic cell cycle.,regulation of meiotic cell cycle,biological_process
79316,GO:0051446,"Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.",positive regulation of meiotic cell cycle,biological_process
79317,GO:0051447,"Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.",negative regulation of meiotic cell cycle,biological_process
79318,GO:0051448,"Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.",gonadotropin-releasing hormone binding,molecular_function
79319,GO:0051449,"Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.",thyrotropin-releasing hormone binding,molecular_function
79320,GO:0051450,"The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast proliferation,biological_process
79321,GO:0051451,"The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.",myoblast migration,biological_process
79322,GO:0051452,"Any process that reduces the internal pH of a cell, corresponding to an increase in hydrogen ion concentration.",intracellular pH reduction,biological_process
79323,GO:0051453,"Any process that modulates the internal pH of a cell, corresponding to a change in hydrogen ion concentration.",regulation of intracellular pH,biological_process
79324,GO:0051454,"Any process that increases the internal pH of a cell, corresponding to a decrease in hydrogen ion concentration.",intracellular pH elevation,biological_process
79325,GO:0051455,The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.,spindle attachment to meiosis I kinetochore,biological_process
79326,GO:0051456,The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.,attachment of meiotic spindle microtubules to meiosis II kinetochore,biological_process
79327,GO:0051457,"Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.",maintenance of protein location in nucleus,biological_process
79328,GO:0051458,The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.,corticotropin secretion,biological_process
79329,GO:0051459,"Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.",regulation of corticotropin secretion,biological_process
79330,GO:0051460,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.",negative regulation of corticotropin secretion,biological_process
79331,GO:0051461,"Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.",positive regulation of corticotropin secretion,biological_process
79332,GO:0051462,"Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.",regulation of cortisol secretion,biological_process
79333,GO:0051463,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.",negative regulation of cortisol secretion,biological_process
79334,GO:0051464,"Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.",positive regulation of cortisol secretion,biological_process
79335,GO:0051465,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.",negative regulation of corticotropin-releasing hormone secretion,biological_process
79336,GO:0051466,"Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.",positive regulation of corticotropin-releasing hormone secretion,biological_process
79337,GO:0051467,The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.,detection of steroid hormone stimulus,biological_process
79338,GO:0051468,"The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.",detection of glucocorticoid hormone stimulus,biological_process
79339,GO:0051469,The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.,vesicle fusion with vacuole,biological_process
79340,GO:0051470,"The directed movement of ectoine across a membrane by means of some agent such as a transporter or a pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.",ectoine transmembrane transport,biological_process
79341,GO:0051472,"The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.",glucosylglycerol metabolic process,biological_process
79342,GO:0051473,"The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.",glucosylglycerol biosynthetic process,biological_process
79343,GO:0051474,"Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.",glucosylglycerol transmembrane transporter activity,molecular_function
79344,GO:0051475,"The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane.",glucosylglycerol transmembrane transport,biological_process
79345,GO:0051476,A phosphoenolpyruvate-dependent sugar phosphotransferase transport specific for mammosylglycerate.,phosphoenolpyruvate-dependent mannosylglycerate phosphotransferase system,biological_process
79346,GO:0051477,Enables the transfer of a mannosylglycerate from one side of a membrane to the other.,mannosylglycerate transmembrane transporter activity,molecular_function
79347,GO:0051478,"The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.",mannosylglycerate metabolic process,biological_process
79348,GO:0051479,"The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.",mannosylglycerate biosynthetic process,biological_process
79349,GO:0051480,Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.,regulation of cytosolic calcium ion concentration,biological_process
79350,GO:0051481,Any process that decreases the concentration of calcium ions in the cytosol.,negative regulation of cytosolic calcium ion concentration,biological_process
79351,GO:0051489,"Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.",regulation of filopodium assembly,biological_process
79352,GO:0051490,"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.",negative regulation of filopodium assembly,biological_process
79353,GO:0051491,"Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.",positive regulation of filopodium assembly,biological_process
79354,GO:0051492,"Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.",regulation of stress fiber assembly,biological_process
79355,GO:0051493,"Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.",regulation of cytoskeleton organization,biological_process
79356,GO:0051494,"Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.",negative regulation of cytoskeleton organization,biological_process
79357,GO:0051495,"Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.",positive regulation of cytoskeleton organization,biological_process
79358,GO:0051496,"Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.",positive regulation of stress fiber assembly,biological_process
79359,GO:0051497,"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.",negative regulation of stress fiber assembly,biological_process
79360,GO:0051498,Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.,syn-copalyl diphosphate synthase activity,molecular_function
79361,GO:0051499,Catalysis of the reaction: a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H+.  Removal of a D-amino acid from a charged tRNA.,D-aminoacyl-tRNA deacylase activity,molecular_function
79362,GO:0051500,Catalysis of the reaction: D-tyrosyl-tRNATyr + H2O = D-tyrosine + tRNATyr. Removal of a D-tyrosine from a charged tRNA(Tyr).,D-tyrosyl-tRNA(Tyr) deacylase activity,molecular_function
79363,GO:0051502,"The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.",diterpene phytoalexin biosynthetic process,biological_process
79364,GO:0051503,"The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",adenine nucleotide transport,biological_process
79365,GO:0051504,A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.,diterpene phytoalexin precursor biosynthetic process,biological_process
79366,GO:0051510,"Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.",regulation of unidimensional cell growth,biological_process
79367,GO:0051511,"Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.",negative regulation of unidimensional cell growth,biological_process
79368,GO:0051512,"Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.",positive regulation of unidimensional cell growth,biological_process
79369,GO:0051513,"Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.",regulation of monopolar cell growth,biological_process
79370,GO:0051514,"Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.",negative regulation of monopolar cell growth,biological_process
79371,GO:0051515,"Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.",positive regulation of monopolar cell growth,biological_process
79372,GO:0051516,"Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.",regulation of bipolar cell growth,biological_process
79373,GO:0051517,"Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.",negative regulation of bipolar cell growth,biological_process
79374,GO:0051518,"Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.",positive regulation of bipolar cell growth,biological_process
79375,GO:0051520,"Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.",termination of bipolar cell growth,biological_process
79376,GO:0051521,"Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.",termination of monopolar cell growth,biological_process
79377,GO:0051522,"Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.",activation of monopolar cell growth,biological_process
79378,GO:0051523,The process in which a cell switches from monopolar cell growth to bipolar cell growth.,"cell growth mode switching, monopolar to bipolar",biological_process
79379,GO:0051524,The process in which a cell switches from bipolar cell growth to monopolar cell growth.,"cell growth mode switching, bipolar to monopolar",biological_process
79380,GO:0051525,"Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.",NFAT protein binding,molecular_function
79381,GO:0051536,"Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.",iron-sulfur cluster binding,molecular_function
79382,GO:0051537,"Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.","2 iron, 2 sulfur cluster binding",molecular_function
79383,GO:0051538,"Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.","3 iron, 4 sulfur cluster binding",molecular_function
79384,GO:0051539,"Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.","4 iron, 4 sulfur cluster binding",molecular_function
79385,GO:0051540,"Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.",metal cluster binding,molecular_function
79386,GO:0051541,"The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.",elastin metabolic process,biological_process
79387,GO:0051546,"The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.",keratinocyte migration,biological_process
79388,GO:0051547,"Any process that modulates the frequency, rate or extent of keratinocyte migration.",regulation of keratinocyte migration,biological_process
79389,GO:0051548,"Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.",negative regulation of keratinocyte migration,biological_process
79390,GO:0051549,"Any process that activates or increases the frequency, rate or extent of keratinocyte migration.",positive regulation of keratinocyte migration,biological_process
79391,GO:0051551,"The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.",aurone biosynthetic process,biological_process
79392,GO:0051552,"The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).",flavone metabolic process,biological_process
79393,GO:0051553,"The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).",flavone biosynthetic process,biological_process
79394,GO:0051554,"The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.",flavonol metabolic process,biological_process
79395,GO:0051555,"The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.",flavonol biosynthetic process,biological_process
79396,GO:0051559,"The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.",phlobaphene biosynthetic process,biological_process
79397,GO:0051560,Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.,mitochondrial calcium ion homeostasis,biological_process
79398,GO:0051561,Any process that increases the concentration of calcium ions in mitochondria.,positive regulation of mitochondrial calcium ion concentration,biological_process
79399,GO:0051562,Any process that decreases the concentration of calcium ions in mitochondria.,negative regulation of mitochondrial calcium ion concentration,biological_process
79400,GO:0051563,Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.,smooth endoplasmic reticulum calcium ion homeostasis,biological_process
79401,GO:0051564,Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.,positive regulation of smooth endoplasmic reticulum calcium ion concentration,biological_process
79402,GO:0051565,Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.,negative regulation of smooth endoplasmic reticulum calcium ion concentration,biological_process
79403,GO:0051566,Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.,anthocyanidin 3-glucoside rhamnosyltransferase activity,molecular_function
79404,GO:0051575,"Catalysis of the reaction: a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+.",5'-deoxyribose-5-phosphate lyase activity,molecular_function
79405,GO:0051580,"Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.",regulation of neurotransmitter uptake,biological_process
79406,GO:0051581,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.",negative regulation of neurotransmitter uptake,biological_process
79407,GO:0051582,"Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.",positive regulation of neurotransmitter uptake,biological_process
79408,GO:0051583,"The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.",dopamine uptake involved in synaptic transmission,biological_process
79409,GO:0051584,"Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.",regulation of dopamine uptake involved in synaptic transmission,biological_process
79410,GO:0051585,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.",negative regulation of dopamine uptake involved in synaptic transmission,biological_process
79411,GO:0051586,"Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.",positive regulation of dopamine uptake involved in synaptic transmission,biological_process
79412,GO:0051588,"Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of neurotransmitter transport,biological_process
79413,GO:0051589,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of neurotransmitter transport,biological_process
79414,GO:0051590,"Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of neurotransmitter transport,biological_process
79415,GO:0051591,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.",response to cAMP,biological_process
79416,GO:0051592,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.",response to calcium ion,biological_process
79417,GO:0051593,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.",response to folic acid,biological_process
79418,GO:0051594,The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.,detection of glucose,biological_process
79419,GO:0051595,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.",response to methylglyoxal,biological_process
79420,GO:0051596,"The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.",methylglyoxal catabolic process,biological_process
79421,GO:0051597,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.",response to methylmercury,biological_process
79422,GO:0051598,"A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.",meiotic recombination checkpoint signaling,biological_process
79423,GO:0051599,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.",response to hydrostatic pressure,biological_process
79424,GO:0051601,"Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.",exocyst localization,biological_process
79425,GO:0051602,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.",response to electrical stimulus,biological_process
79426,GO:0051604,Any process leading to the attainment of the full functional capacity of a protein.,protein maturation,biological_process
79427,GO:0051606,The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.,detection of stimulus,biological_process
79428,GO:0051607,Reactions triggered in response to the presence of a virus that act to protect the cell or organism.,defense response to virus,biological_process
79429,GO:0051608,"The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine transport,biological_process
79430,GO:0051609,Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.,inhibition of neurotransmitter uptake,biological_process
79431,GO:0051610,"The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.",serotonin uptake,biological_process
79432,GO:0051611,"Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.",regulation of serotonin uptake,biological_process
79433,GO:0051612,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.",negative regulation of serotonin uptake,biological_process
79434,GO:0051613,"Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.",positive regulation of serotonin uptake,biological_process
79435,GO:0051614,Any process that prevents the activation of the directed movement of serotonin into a cell.,inhibition of serotonin uptake,biological_process
79436,GO:0051615,"The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.",histamine uptake,biological_process
79437,GO:0051616,"Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.",regulation of histamine uptake,biological_process
79438,GO:0051617,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.",negative regulation of histamine uptake,biological_process
79439,GO:0051618,"Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.",positive regulation of histamine uptake,biological_process
79440,GO:0051619,Any process that prevents the activation of the directed movement of histamine into a cell.,inhibition of histamine uptake,biological_process
79441,GO:0051620,"The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.",norepinephrine uptake,biological_process
79442,GO:0051621,"Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.",regulation of norepinephrine uptake,biological_process
79443,GO:0051622,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.",negative regulation of norepinephrine uptake,biological_process
79444,GO:0051623,"Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.",positive regulation of norepinephrine uptake,biological_process
79445,GO:0051624,Any process that prevents the activation of the directed movement of norepinephrine into a cell.,inhibition of norepinephrine uptake,biological_process
79446,GO:0051625,"The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.",epinephrine uptake,biological_process
79447,GO:0051626,"Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.",regulation of epinephrine uptake,biological_process
79448,GO:0051627,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.",negative regulation of epinephrine uptake,biological_process
79449,GO:0051628,"Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.",positive regulation of epinephrine uptake,biological_process
79450,GO:0051629,Any process that prevents the activation of the directed movement of epinephrine into a cell.,inhibition of epinephrine uptake,biological_process
79451,GO:0051630,"The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.",acetylcholine uptake,biological_process
79452,GO:0051631,"Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.",regulation of acetylcholine uptake,biological_process
79453,GO:0051632,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.",negative regulation of acetylcholine uptake,biological_process
79454,GO:0051633,"Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.",positive regulation of acetylcholine uptake,biological_process
79455,GO:0051634,Any process that prevents the activation of the directed movement of acetylcholine into a cell.,inhibition of acetylcholine uptake,biological_process
79456,GO:0051638,"The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.",barbed-end actin filament uncapping,biological_process
79457,GO:0051639,The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.,actin filament network formation,biological_process
79458,GO:0051640,"Any process in which an organelle is transported to, and/or maintained in, a specific location.",organelle localization,biological_process
79459,GO:0051641,"A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.",cellular localization,biological_process
79460,GO:0051642,"Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.",centrosome localization,biological_process
79461,GO:0051643,"Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.",endoplasmic reticulum localization,biological_process
79462,GO:0051644,"Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.",plastid localization,biological_process
79463,GO:0051645,"Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.",Golgi localization,biological_process
79464,GO:0051646,"Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.",mitochondrion localization,biological_process
79465,GO:0051647,"Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.",nucleus localization,biological_process
79466,GO:0051648,"Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.",vesicle localization,biological_process
79467,GO:0051649,"Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.",establishment of localization in cell,biological_process
79468,GO:0051650,The directed movement of a vesicle to a specific location.,establishment of vesicle localization,biological_process
79469,GO:0051651,"Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.",maintenance of location in cell,biological_process
79470,GO:0051653,"Any process in which is the spindle is transported to, and/or maintained in, a specific location.",spindle localization,biological_process
79471,GO:0051654,The directed movement of the mitochondrion to a specific location.,establishment of mitochondrion localization,biological_process
79472,GO:0051655,Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of vesicle location,biological_process
79473,GO:0051656,The directed movement of an organelle to a specific location.,establishment of organelle localization,biological_process
79474,GO:0051657,Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of organelle location,biological_process
79475,GO:0051658,Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of nucleus location,biological_process
79476,GO:0051659,Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of mitochondrion location,biological_process
79477,GO:0051660,The directed movement of the centrosome to a specific location.,establishment of centrosome localization,biological_process
79478,GO:0051661,Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of centrosome location,biological_process
79479,GO:0051663,The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.,oocyte nucleus localization involved in oocyte dorsal/ventral axis specification,biological_process
79480,GO:0051664,"Any process in which nuclear pores are transported to, or maintained in, a specific location.",nuclear pore localization,biological_process
79481,GO:0051665,"Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.",membrane raft localization,biological_process
79482,GO:0051666,"Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.",actin cortical patch localization,biological_process
79483,GO:0051667,The directed movement of a plastid to a specific location in the cell.,establishment of plastid localization,biological_process
79484,GO:0051668,"Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.",localization within membrane,biological_process
79485,GO:0051669,"Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.",fructan beta-fructosidase activity,molecular_function
79486,GO:0051670,"Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.",inulinase activity,molecular_function
79487,GO:0051673,"The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane.",disruption of plasma membrane integrity in another organism,biological_process
79488,GO:0051674,"Any process in which a cell is transported to, and/or maintained in, a specific location.",localization of cell,biological_process
79489,GO:0051675,Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).,isopullulanase activity,molecular_function
79490,GO:0051676,"The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.",pullulan metabolic process,biological_process
79491,GO:0051677,"The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.",pullulan biosynthetic process,biological_process
79492,GO:0051678,"The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.",pullulan catabolic process,biological_process
79493,GO:0051680,"The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.",6-alpha-maltosylglucose biosynthetic process,biological_process
79494,GO:0051681,"The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.",6-alpha-maltosylglucose catabolic process,biological_process
79495,GO:0051682,"The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.",galactomannan catabolic process,biological_process
79496,GO:0051683,The directed movement of the Golgi to a specific location.,establishment of Golgi localization,biological_process
79497,GO:0051684,Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of Golgi location,biological_process
79498,GO:0051685,Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of ER location,biological_process
79499,GO:0051686,The directed movement of the endoplasmic reticulum to a specific location.,establishment of ER localization,biological_process
79500,GO:0051687,Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of spindle location,biological_process
79501,GO:0051688,Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.,maintenance of plastid location,biological_process
79502,GO:0051693,"The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.",actin filament capping,biological_process
79503,GO:0051694,"The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.",pointed-end actin filament capping,biological_process
79504,GO:0051695,"The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.",actin filament uncapping,biological_process
79505,GO:0051696,"The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.",pointed-end actin filament uncapping,biological_process
79506,GO:0051697,The breakage of covalent bonds to detach lipid groups from a protein.,protein delipidation,biological_process
79507,GO:0051698,Catalysis of the reaction: H2O + L-saccharopine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate.,saccharopine oxidase activity,molecular_function
79508,GO:0051700,Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.,fructosyl-amino acid oxidase activity,molecular_function
79509,GO:0051701,"An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.",biological process involved in interaction with host,biological_process
79510,GO:0051702,"An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.",biological process involved in interaction with symbiont,biological_process
79511,GO:0051703,Any process in which an organism has an effect on an organism of the same species.,biological process involved in intraspecies interaction between organisms,biological_process
79512,GO:0051707,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.",response to other organism,biological_process
79513,GO:0051709,"Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.",regulation of killing of cells of another organism,biological_process
79514,GO:0051711,"Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.",negative regulation of killing of cells of another organism,biological_process
79515,GO:0051712,"Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.",positive regulation of killing of cells of another organism,biological_process
79516,GO:0051715,The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.,cytolysis in another organism,biological_process
79517,GO:0051716,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.",cellular response to stimulus,biological_process
79518,GO:0051717,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.","inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity",molecular_function
79519,GO:0051718,Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).,"DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates",molecular_function
79520,GO:0051719,Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.,"DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates",molecular_function
79521,GO:0051720,Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.,"DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates",molecular_function
79522,GO:0051721,Binding to protein phosphatase 2A.,protein phosphatase 2A binding,molecular_function
79523,GO:0051723,Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.,protein methylesterase activity,molecular_function
79524,GO:0051724,Enables the transfer of NAD from one side of a membrane to the other.,NAD transmembrane transporter activity,molecular_function
79525,GO:0051725,The process of removing one or more ADP-ribose residues from a protein.,protein de-ADP-ribosylation,biological_process
79526,GO:0051726,Any process that modulates the rate or extent of progression through the cell cycle.,regulation of cell cycle,biological_process
79527,GO:0051728,The process in which a cell switches cell cycle mode from mitotic to meiotic division.,"cell cycle switching, mitotic to meiotic cell cycle",biological_process
79528,GO:0051729,The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.,"germline cell cycle switching, mitotic to meiotic cell cycle",biological_process
79529,GO:0051730,Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.,GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity,molecular_function
79530,GO:0051731,Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.,polynucleotide 5'-hydroxyl-kinase activity,molecular_function
79531,GO:0051734,Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.,ATP-dependent polynucleotide 5'-hydroxyl-kinase activity,molecular_function
79532,GO:0051735,Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.,GTP-dependent polynucleotide 5'-hydroxyl-kinase activity,molecular_function
79533,GO:0051736,Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.,ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity,molecular_function
79534,GO:0051737,Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.,GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity,molecular_function
79535,GO:0051738,"Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.",xanthophyll binding,molecular_function
79536,GO:0051740,"Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.",ethylene binding,molecular_function
79537,GO:0051741,"Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.","2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity",molecular_function
79538,GO:0051742,"Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.","2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity",molecular_function
79539,GO:0051743,Catalysis of the reaction: primary fluorescent chlorophyll catabolite + 2 oxidized [2Fe-2S]-[ferredoxin] = red chlorophyll catabolite + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H+. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.,red chlorophyll catabolite reductase activity,molecular_function
79540,GO:0051745,Catalyzes the conversion of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H+ + 2 reduced [2Fe-2S]-[ferredoxin] to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) releasing H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.,4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity,molecular_function
79541,GO:0051746,"Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).",thalianol synthase activity,molecular_function
79542,GO:0051747,Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.,cytosine C-5 DNA demethylase activity,molecular_function
79543,GO:0051748,Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.,UTP-monosaccharide-1-phosphate uridylyltransferase activity,molecular_function
79544,GO:0051749,Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.,indole acetic acid carboxyl methyltransferase activity,molecular_function
79545,GO:0051750,"Catalysis of the reaction: a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.","delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity",molecular_function
79546,GO:0051751,"Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.","alpha-1,4-mannosyltransferase activity",molecular_function
79547,GO:0051752,"Catalysis of the reaction: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-3,6-bisphospho-alpha-alpha-glucosyl](n) + n AMP + 2n H+ + n phosphate.","phosphoglucan, water dikinase activity",molecular_function
79548,GO:0051753,Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.,mannan synthase activity,molecular_function
79549,GO:0051754,The cell cycle process in which centromeres of sister chromatids are joined during meiosis.,"meiotic sister chromatid cohesion, centromeric",biological_process
79550,GO:0051755,The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.,meiotic sister chromatid arm separation,biological_process
79551,GO:0051756,The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.,meiotic sister chromatid centromere separation,biological_process
79552,GO:0051757,The process in which sister chromatids are physically detached from each other during meiosis.,meiotic sister chromatid separation,biological_process
79553,GO:0051758,"The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.",homologous chromosome movement towards spindle pole in meiosis I anaphase,biological_process
79554,GO:0051759,"The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.",sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation,biological_process
79555,GO:0051761,"The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.",sesquiterpene metabolic process,biological_process
79556,GO:0051762,"The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.",sesquiterpene biosynthetic process,biological_process
79557,GO:0051763,"The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.",sesquiterpene catabolic process,biological_process
79558,GO:0051764,The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.,actin crosslink formation,biological_process
79559,GO:0051765,Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.,inositol tetrakisphosphate kinase activity,molecular_function
79560,GO:0051766,Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP + H+.,inositol trisphosphate kinase activity,molecular_function
79561,GO:0051775,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.",response to redox state,biological_process
79562,GO:0051776,"The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.",detection of redox state,biological_process
79563,GO:0051777,Catalysis of the reaction:ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Catalyzes three successive oxidations of ent-kaurenoic acid.,ent-kaurenoic acid monooxygenase activity,molecular_function
79564,GO:0051780,Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.,behavioral response to nutrient,biological_process
79565,GO:0051781,"Any process that activates or increases the frequency, rate or extent of cell division.",positive regulation of cell division,biological_process
79566,GO:0051782,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.",negative regulation of cell division,biological_process
79567,GO:0051783,"Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.",regulation of nuclear division,biological_process
79568,GO:0051784,"Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.",negative regulation of nuclear division,biological_process
79569,GO:0051785,"Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.",positive regulation of nuclear division,biological_process
79570,GO:0051786,"Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.","all-trans-retinol 13,14-reductase activity",molecular_function
79571,GO:0051787,Binding to a misfolded protein.,misfolded protein binding,molecular_function
79572,GO:0051788,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.",response to misfolded protein,biological_process
79573,GO:0051790,The chemical reactions and pathways resulting in the formation of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.,short-chain fatty acid biosynthetic process,biological_process
79574,GO:0051791,The chemical reactions and pathways involving a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid metabolic process,biological_process
79575,GO:0051792,The chemical reactions and pathways resulting in the formation of a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid biosynthetic process,biological_process
79576,GO:0051793,The chemical reactions and pathways resulting in the breakdown of a medium-chain fatty acid. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid catabolic process,biological_process
79577,GO:0051794,"Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.",regulation of timing of catagen,biological_process
79578,GO:0051795,"Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.",positive regulation of timing of catagen,biological_process
79579,GO:0051796,"Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.",negative regulation of timing of catagen,biological_process
79580,GO:0051797,"Any process that modulates the frequency, rate or extent of hair follicle development.",regulation of hair follicle development,biological_process
79581,GO:0051798,"Any process that activates or increases the frequency, rate or extent of hair follicle development.",positive regulation of hair follicle development,biological_process
79582,GO:0051799,"Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.",negative regulation of hair follicle development,biological_process
79583,GO:0051800,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.","phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity",molecular_function
79584,GO:0051819,"The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.",symbiont-mediated induction of tumor or growth in host,biological_process
79585,GO:0051823,"Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors in...",regulation of synapse structural plasticity,biological_process
79586,GO:0051826,"Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.",negative regulation of synapse structural plasticity,biological_process
79587,GO:0051835,"Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.",positive regulation of synapse structural plasticity,biological_process
79588,GO:0051844,The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,translocation of peptides or proteins into symbiont,biological_process
79589,GO:0051850,The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,acquisition of nutrients from symbiont,biological_process
79590,GO:0051851,The process in which an host alters or subverts a process in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,host-mediated perturbation of symbiont process,biological_process
79591,GO:0051861,"Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.",glycolipid binding,molecular_function
79592,GO:0051862,The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,translocation of molecules into symbiont,biological_process
79593,GO:0051864,Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K36 demethylase activity,molecular_function
79594,GO:0051865,"The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.",protein autoubiquitination,biological_process
79595,GO:0051866,"General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.",general adaptation syndrome,biological_process
79596,GO:0051867,"The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.","general adaptation syndrome, behavioral process",biological_process
79597,GO:0051870,"Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.",methotrexate binding,molecular_function
79598,GO:0051871,"Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.",dihydrofolic acid binding,molecular_function
79599,GO:0051872,"The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.",sphingosine catabolic process,biological_process
79600,GO:0051874,"The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.",sphinganine-1-phosphate catabolic process,biological_process
79601,GO:0051875,"Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.",pigment granule localization,biological_process
79602,GO:0051876,The directed movement of pigment granules within a cell towards the cell periphery.,pigment granule dispersal,biological_process
79603,GO:0051877,The directed movement of dispersed pigment granules towards the center of the cell.,pigment granule aggregation in cell center,biological_process
79604,GO:0051878,"The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements.",lateral element assembly,biological_process
79605,GO:0051879,"Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.",Hsp90 protein binding,molecular_function
79606,GO:0051880,"Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.",G-quadruplex DNA binding,molecular_function
79607,GO:0051881,"Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.",regulation of mitochondrial membrane potential,biological_process
79608,GO:0051882,The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.,mitochondrial depolarization,biological_process
79609,GO:0051884,"Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.",regulation of timing of anagen,biological_process
79610,GO:0051885,"Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.",positive regulation of timing of anagen,biological_process
79611,GO:0051886,"Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.",negative regulation of timing of anagen,biological_process
79612,GO:0051887,"Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.",regulation of timing of exogen,biological_process
79613,GO:0051888,"Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.",positive regulation of timing of exogen,biological_process
79614,GO:0051889,"Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.",negative regulation of timing of exogen,biological_process
79615,GO:0051890,"Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",regulation of cardioblast differentiation,biological_process
79616,GO:0051891,"Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",positive regulation of cardioblast differentiation,biological_process
79617,GO:0051892,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",negative regulation of cardioblast differentiation,biological_process
79618,GO:0051893,"Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.",regulation of focal adhesion assembly,biological_process
79619,GO:0051894,"Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.",positive regulation of focal adhesion assembly,biological_process
79620,GO:0051895,"Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.",negative regulation of focal adhesion assembly,biological_process
79621,GO:0051896,"Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.",regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process
79622,GO:0051897,"Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.",positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process
79623,GO:0051898,"Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.",negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction,biological_process
79624,GO:0051899,"The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.",membrane depolarization,biological_process
79625,GO:0051900,"Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.",regulation of mitochondrial depolarization,biological_process
79626,GO:0051901,"Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.",positive regulation of mitochondrial depolarization,biological_process
79627,GO:0051902,"Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.",negative regulation of mitochondrial depolarization,biological_process
79628,GO:0051903,Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.,S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity,molecular_function
79629,GO:0051904,"The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",pigment granule transport,biological_process
79630,GO:0051905,The directed movement of a pigment granule to a specific location.,establishment of pigment granule localization,biological_process
79631,GO:0051906,Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.,maintenance of pigment granule location,biological_process
79632,GO:0051907,Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione.,S-(hydroxymethyl)glutathione synthase activity,molecular_function
79633,GO:0051908,Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.,double-stranded DNA 5'-3' DNA exonuclease activity,molecular_function
79634,GO:0051911,"Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine.",Methanosarcina-phenazine hydrogenase activity,molecular_function
79635,GO:0051912,Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.,CoB--CoM heterodisulfide reductase activity,molecular_function
79636,GO:0051913,"The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require.",regulation of synaptic plasticity by chemical substance,biological_process
79637,GO:0051914,"The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.",positive regulation of synaptic plasticity by chemical substance,biological_process
79638,GO:0051915,"The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.",induction of synaptic plasticity by chemical substance,biological_process
79639,GO:0051916,"Binding to granulocyte colony-stimulating factor, G-CSF.",granulocyte colony-stimulating factor binding,molecular_function
79640,GO:0051917,"Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.",regulation of fibrinolysis,biological_process
79641,GO:0051918,"Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.",negative regulation of fibrinolysis,biological_process
79642,GO:0051919,"Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.",positive regulation of fibrinolysis,biological_process
79643,GO:0051920,Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.,peroxiredoxin activity,molecular_function
79644,GO:0051921,"Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H+ + 4 phosphate.",adenosylcobyric acid synthase (glutamine-hydrolyzing) activity,molecular_function
79645,GO:0051922,"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate + H+.",cholesterol sulfotransferase activity,molecular_function
79646,GO:0051923,The addition of a sulfate group to a molecule.,sulfation,biological_process
79647,GO:0051924,"Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of calcium ion transport,biological_process
79648,GO:0051926,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of calcium ion transport,biological_process
79649,GO:0051928,"Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of calcium ion transport,biological_process
79650,GO:0051930,"Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.",regulation of sensory perception of pain,biological_process
79651,GO:0051931,"Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.",regulation of sensory perception,biological_process
79652,GO:0051932,"The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts...","synaptic transmission, GABAergic",biological_process
79653,GO:0051933,The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.,amino acid neurotransmitter reuptake,biological_process
79654,GO:0051935,The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.,glutamate reuptake,biological_process
79655,GO:0051936,"The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.",gamma-aminobutyric acid reuptake,biological_process
79656,GO:0051938,"The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.",L-glutamate import,biological_process
79657,GO:0051939,"The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.",gamma-aminobutyric acid import,biological_process
79658,GO:0051944,"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.",positive regulation of catecholamine uptake involved in synaptic transmission,biological_process
79659,GO:0051946,"Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.",regulation of glutamate uptake involved in transmission of nerve impulse,biological_process
79660,GO:0051951,"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.",positive regulation of glutamate uptake involved in transmission of nerve impulse,biological_process
79661,GO:0051952,"Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of amine transport,biological_process
79662,GO:0051953,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of amine transport,biological_process
79663,GO:0051954,"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of amine transport,biological_process
79664,GO:0051955,"Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of amino acid transport,biological_process
79665,GO:0051956,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of amino acid transport,biological_process
79666,GO:0051957,"Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of amino acid transport,biological_process
79667,GO:0051958,"The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.",methotrexate transport,biological_process
79668,GO:0051959,Binding to a light intermediate chain of the dynein complex.,dynein light intermediate chain binding,molecular_function
79669,GO:0051960,"Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.",regulation of nervous system development,biological_process
79670,GO:0051961,"Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.",negative regulation of nervous system development,biological_process
79671,GO:0051962,"Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.",positive regulation of nervous system development,biological_process
79672,GO:0051963,"Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.",regulation of synapse assembly,biological_process
79673,GO:0051964,"Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.",negative regulation of synapse assembly,biological_process
79674,GO:0051965,"Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.",positive regulation of synapse assembly,biological_process
79675,GO:0051966,"Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.","regulation of synaptic transmission, glutamatergic",biological_process
79676,GO:0051967,"Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.","negative regulation of synaptic transmission, glutamatergic",biological_process
79677,GO:0051968,"Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.","positive regulation of synaptic transmission, glutamatergic",biological_process
79678,GO:0051969,"Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.",regulation of transmission of nerve impulse,biological_process
79679,GO:0051970,"Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.",negative regulation of transmission of nerve impulse,biological_process
79680,GO:0051971,"Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.",positive regulation of transmission of nerve impulse,biological_process
79681,GO:0051977,"The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.",lysophospholipid transport,biological_process
79682,GO:0051978,Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.,lysophospholipid:sodium symporter activity,molecular_function
79683,GO:0051979,"The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.",alginic acid acetylation,biological_process
79684,GO:0051980,Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other.,iron-nicotianamine transmembrane transporter activity,molecular_function
79685,GO:0051981,Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.,copper chelate transmembrane transporter activity,molecular_function
79686,GO:0051982,Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.,copper-nicotianamine transmembrane transporter activity,molecular_function
79687,GO:0051983,"Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.",regulation of chromosome segregation,biological_process
79688,GO:0051984,"Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.",positive regulation of chromosome segregation,biological_process
79689,GO:0051985,"Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.",negative regulation of chromosome segregation,biological_process
79690,GO:0051986,"Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.",negative regulation of attachment of spindle microtubules to kinetochore,biological_process
79691,GO:0051987,"Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.",positive regulation of attachment of spindle microtubules to kinetochore,biological_process
79692,GO:0051988,"Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.",regulation of attachment of spindle microtubules to kinetochore,biological_process
79693,GO:0051989,Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.,coproporphyrinogen dehydrogenase activity,molecular_function
79694,GO:0051990,Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.,(R)-2-hydroxyglutarate dehydrogenase activity,molecular_function
79695,GO:0051991,"Catalysis of the reaction: di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H+ + UDP.","UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity",molecular_function
79696,GO:0051992,"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP.","UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity",molecular_function
79697,GO:0051993,Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.,abscisic acid glucose ester beta-glucosidase activity,molecular_function
79698,GO:0051995,Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.,Se-methyltransferase activity,molecular_function
79699,GO:0051996,"Catalysis of the reaction: 2 (2E,6E)-farnesyl diphosphate + H+ + NAD(P)H = 2 diphosphate + NAD(P)+ + squalene.",squalene synthase [NAD(P)H] activity,molecular_function
79700,GO:0051997,"Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.",2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity,molecular_function
79701,GO:0051998,Catalysis of the transfer of a methyl group to a carboxyl group on a protein.,protein carboxyl O-methyltransferase activity,molecular_function
79702,GO:0051999,"The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.",mannosyl-inositol phosphorylceramide biosynthetic process,biological_process
79703,GO:0052001,Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion to host cell via type IV pili,biological_process
79704,GO:0052003,"A process in which a virus interferes with, inhibits or disrupts a host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway,biological_process
79705,GO:0052005,A process in which a symbiont inhibits or disrupts the normal execution of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host ethylene-mediated defense response,biological_process
79706,GO:0052008,The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical structure. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cellular anatomical structure,biological_process
79707,GO:0052009,The process in which an organism effects a change that impairs the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cell wall,biological_process
79708,GO:0052025,The process in which an organism effects a change that impairs the structure or function of the host endomembrane system. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cell endomembrane system,biological_process
79709,GO:0052026,A process in which a symbiont alters or subverts transcription in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host transcription,biological_process
79710,GO:0052027,A process in which a symbiont alters or subverts a signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host signal transduction pathway,biological_process
79711,GO:0052028,"A process in which a symbiont subverts a signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host signal transduction pathway,biological_process
79712,GO:0052029,"A process in which a symbiont interferes with, inhibits or disrupts a host signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host signal transduction pathway,biological_process
79713,GO:0052031,A process in which a symbiont interferes with the ability of the host to mount a defense in response to its presence. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host defense response,biological_process
79714,GO:0052032,A process in which a symbiont alters or subverts the normal execution of the  inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host inflammatory response,biological_process
79715,GO:0052034,A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated suppression of host pattern-triggered immunity,biological_process
79716,GO:0052036,A process in which a symbiont inhibits or disrupts the normal execution of  inflammatory response in the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host inflammatory response,biological_process
79717,GO:0052038,A process in which a symbiont alters or subverts the directed movement of substances within the cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host intracellular transport,biological_process
79718,GO:0052039,The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cytoskeleton,biological_process
79719,GO:0052040,"A process in which a symbiont gene product alters or subverts host programmed cell death, leading to a change in the frequency, rate or extent of host programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host programmed cell death,biological_process
79720,GO:0052041,"A process in which a symbiont inhibits or disrupts the normal execution of host programmed cell death, leading to a decrease in the frequency, rate or extent of programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host programmed cell death,biological_process
79721,GO:0052042,"A process in which a symbiont gene product activates host programmed cell death, leading to an increase in the frequency, rate or extent of programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host programmed cell death,biological_process
79722,GO:0052067,A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host phagocytosis,biological_process
79723,GO:0052078,"A process in which a symbiont interferes with, inhibits or disrupts a PAMP signaling pathway in its host organism, initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway,biological_process
79724,GO:0052080,A process in which a symbiont alters or subverts a MAP kinase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host MAPK cascade,biological_process
79725,GO:0052081,A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host salicylic acid-mediated signal transduction pathway,biological_process
79726,GO:0052084,"Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated modulation of host ethylene-mediated defense response,biological_process
79727,GO:0052085,"A process by which a symbiont interferes with, inhibits or disrupts the normal execution of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host T-cell mediated immune response,biological_process
79728,GO:0052086,"A process by which a symbiont interferes with, inhibits or disrupts the normal execution of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host B-cell mediated immune response,biological_process
79729,GO:0052088,A process in which a symbiont alters or subverts a jasmonic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host jasmonic acid signaling,biological_process
79730,GO:0052091,"Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",modulation of nutrient release by host,biological_process
79731,GO:0052092,"Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of nutrient release by host,biological_process
79732,GO:0052093,The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,formation of specialized structure for nutrient acquisition,biological_process
79733,GO:0052094,"The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.",formation of haustorium for nutrient acquisition,biological_process
79734,GO:0052096,"The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",formation of syncytium involving giant cell for nutrient acquisition,biological_process
79735,GO:0052098,The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,formation by host of specialized structure for nutrient acquisition from symbiont,biological_process
79736,GO:0052103,"Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host induced systemic resistance,biological_process
79737,GO:0052111,The process in which an organism effects a change that impairs the structure or function of an anatomical structure of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host anatomical structure,biological_process
79738,GO:0052112,"The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated occlusion of host xylem,biological_process
79739,GO:0052128,"The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.",positive energy taxis,biological_process
79740,GO:0052129,"The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.",negative energy taxis,biological_process
79741,GO:0052130,The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.,negative aerotaxis,biological_process
79742,GO:0052131,The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.,positive aerotaxis,biological_process
79743,GO:0052150,"A process in which a symbiont gene product affects host apoptosis, leading to a change in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host apoptosis,biological_process
79744,GO:0052151,"A process in which a symbiont initiates, promotes, or enhances the normal execution of host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host apoptosis,biological_process
79745,GO:0052154,A process in which a symbiont alters or subverts the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host B-cell mediated immune response,biological_process
79746,GO:0052156,A process in which a symbiont alters or subverts the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host T-cell mediated immune response,biological_process
79747,GO:0052158,"Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host resistance gene-dependent defense response,biological_process
79748,GO:0052159,A process in which a symbiont alters or subverts the induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host induced systemic resistance,biological_process
79749,GO:0052160,A process in which a symbiont alters or subverts systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host systemic acquired resistance,biological_process
79750,GO:0052164,A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response.,symbiont defense to host-produced reactive oxygen species,biological_process
79751,GO:0052165,"Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host phytoalexin production,biological_process
79752,GO:0052167,A process in which a symbiont alters or subverts the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host innate immune response,biological_process
79753,GO:0052170,"A process in which a symbiont inhibits or disrupts the normal execution of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host innate immune response,biological_process
79754,GO:0052200,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated response to host defenses,biological_process
79755,GO:0052314,"The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.",phytoalexin metabolic process,biological_process
79756,GO:0052315,"The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.",phytoalexin biosynthetic process,biological_process
79757,GO:0052316,"The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.",phytoalexin catabolic process,biological_process
79758,GO:0052322,"Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.",positive regulation of phytoalexin biosynthetic process,biological_process
79759,GO:0052324,"The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.",plant-type cell wall cellulose biosynthetic process,biological_process
79760,GO:0052325,"The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.",cell wall pectin biosynthetic process,biological_process
79761,GO:0052372,"Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.",modulation by symbiont of entry into host,biological_process
79762,GO:0052373,"Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.",suppression of symbiont entry into host,biological_process
79763,GO:0052381,Catalysis of the reaction: adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate.,tRNA dimethylallyltransferase activity,molecular_function
79764,GO:0052386,A type of cell wall modification in which the cell wall is reinforced and made thicker.,cell wall thickening,biological_process
79765,GO:0052460,"Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.",modulation of nutrient release by symbiont,biological_process
79766,GO:0052482,"A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism.",defense response by cell wall thickening,biological_process
79767,GO:0052519,"Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.",positive regulation of nutrient release by symbiont,biological_process
79768,GO:0052541,"The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.",plant-type cell wall cellulose metabolic process,biological_process
79769,GO:0052542,"Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.",defense response by callose deposition,biological_process
79770,GO:0052543,"Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.",callose deposition in cell wall,biological_process
79771,GO:0052544,"Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.",defense response by callose deposition in cell wall,biological_process
79772,GO:0052545,"Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.",callose localization,biological_process
79773,GO:0052546,"The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.",cell wall pectin metabolic process,biological_process
79774,GO:0052547,"Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.",regulation of peptidase activity,biological_process
79775,GO:0052548,"Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.",regulation of endopeptidase activity,biological_process
79776,GO:0052553,A process in which a symbiont alters or subverts the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host immune response,biological_process
79777,GO:0052562,"A process in which a symbiont interferes with, inhibits or disrupts the normal execution of an immune response of the host organism. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host immune response,biological_process
79778,GO:0052572,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host immune response,biological_process
79779,GO:0052573,"The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.",UDP-D-galactose metabolic process,biological_process
79780,GO:0052574,"The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.",UDP-galactose biosynthetic process,biological_process
79781,GO:0052575,"Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate localization,biological_process
79782,GO:0052576,"The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.",carbohydrate storage,biological_process
79783,GO:0052577,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (-)-germacrene D + diphosphate.",germacrene-D synthase activity,molecular_function
79784,GO:0052578,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate.",alpha-farnesene synthase activity,molecular_function
79785,GO:0052579,"Catalysis of the reaction: (1R,4S)-menthone + NADP+ = (R)-pulegone + H+ + NADPH. Also converts (2R,5R)-isomenthone into (R)-pulegone.",(+)-pulegone reductase (NADP+) activity,molecular_function
79786,GO:0052581,"Catalysis of the reaction: (6R)-isoperitenone + H+ + NADPH = (2R,5R)-isopulegone + NADP+.",(-)-isopiperitenone reductase activity,molecular_function
79787,GO:0052582,Catalysis of the reaction: (R)-pulegone + reduced [NADPH--hemoprotein reductase] + O2 = (R)-menthofuran + 2 H2O + +H+ + oxidized [NADPH--hemoprotein reductase].,(+)-menthofuran synthase activity,molecular_function
79788,GO:0052587,Catalysis of the reaction: (R)-acetoin + NAD+ = diacetyl + H+ + NADH. This reaction is catalyzed in the reverse direction.,diacetyl reductase ((R)-acetoin forming) (NAD+) activity,molecular_function
79789,GO:0052588,Catalysis of the reaction: (S)-acetoin + NAD+ = diacetyl + H+ + NADH. This reaction is catalyzed in the reverse direction.,diacetyl reductase ((S)-acetoin forming) (NAD+) activity,molecular_function
79790,GO:0052592,Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.,"oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor",molecular_function
79791,GO:0052597,Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH4+ + H2O2.,diamine oxidase activity,molecular_function
79792,GO:0052598,Catalysis of the reaction: H2O + histamine + O2 = H2O2 + imidazole-4-acetaldehyde + NH4+.,histamine oxidase activity,molecular_function
79793,GO:0052601,"Catalysis of the reaction: limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + limonene-1,2-epoxide. Can use either (4S)-limonene or (4R)-limonene as substrate. NADPH can act instead of NADH, although more slowly.","limonene 1,2-monooxygenase [NAD(P)H) activity",molecular_function
79794,GO:0052614,Catalysis of the reaction: FMNH2 + NADH + O2 + uracil = (Z)-3-ureidoacrylate + FMN + H+ + H2O + NAD+. Can also use thymine as a substrate.,uracil oxygenase activity,molecular_function
79795,GO:0052615,Catalysis of the reaction: ent-kaur-16-ene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = ent-kaur-16-en-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].,ent-kaurene oxidase activity,molecular_function
79796,GO:0052618,Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.,coenzyme F420-0:L-glutamate ligase activity,molecular_function
79797,GO:0052619,Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.,coenzyme F420-1:gamma-L-glutamate ligase activity,molecular_function
79798,GO:0052620,Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.,thymine dehydrogenase activity,molecular_function
79799,GO:0052621,"Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H+.",diguanylate cyclase activity,molecular_function
79800,GO:0052622,Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.,ATP/ADP dimethylallyltransferase activity,molecular_function
79801,GO:0052624,Catalysis of the reaction: demethylphylloquinol + S-adenosyl-L-methionine = H+ + phylloquinol + S-adenosyl-L-homocysteine.,"2-phytyl-1,4-naphthoquinone methyltransferase activity",molecular_function
79802,GO:0052625,Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP = N-(4-aminobenzoyl)-L-glutamate + AMP + diphosphate + H+.,N-(4-aminobenzoyl)-L-glutamate synthetase activity,molecular_function
79803,GO:0052626,Catalysis of the reaction: benzoate + L-glutamate + ATP = N-benzoyl-L-glutamate + AMP + diphosphate + H+.,N-benzoyl-L-glutamate synthetase activity,molecular_function
79804,GO:0052627,Catalysis of the reaction: vanillate + L-glutamate + ATP = N-vanillate-L-glutamate + AMP + diphosphate + H+.,N-vanillate-L-glutamate synthetase activity,molecular_function
79805,GO:0052628,Catalysis of the reaction: 4-hydroxybenzoate + L-glutamate + ATP = N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphate + H+.,N-(4-hydroxybenzoyl)-L-glutamate synthetase activity,molecular_function
79806,GO:0052629,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.","phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity",molecular_function
79807,GO:0052630,Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine.,UDP-N-acetylgalactosamine diphosphorylase activity,molecular_function
79808,GO:0052631,"Catalysis of the reaction: an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (4R,8E)-4-hydroxysphingenine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O or an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (4R,8Z)-4-hydroxysphing-8-enine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O. This results in the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid.",sphingolipid 8-(E/Z)-desaturase activity,molecular_function
79809,GO:0052636,Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).,arabinosyltransferase activity,molecular_function
79810,GO:0052638,Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.,indole-3-butyrate beta-glucosyltransferase activity,molecular_function
79811,GO:0052639,Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP.,salicylic acid glucosyltransferase (ester-forming) activity,molecular_function
79812,GO:0052640,Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.,salicylic acid glucosyltransferase (glucoside-forming) activity,molecular_function
79813,GO:0052641,Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP.,benzoic acid glucosyltransferase activity,molecular_function
79814,GO:0052642,Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.,lysophosphatidic acid phosphatase activity,molecular_function
79815,GO:0052645,"The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.",F420-0 metabolic process,biological_process
79816,GO:0052646,"The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.",alditol phosphate metabolic process,biological_process
79817,GO:0052650,Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.,all-trans-retinol dehydrogenase (NADP+) activity,molecular_function
79818,GO:0052651,"The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.",monoacylglycerol catabolic process,biological_process
79819,GO:0052652,"The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.",cyclic purine nucleotide metabolic process,biological_process
79820,GO:0052654,Catalysis of the reaction:L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.,L-leucine:2-oxoglutarate transaminase activity,molecular_function
79821,GO:0052655,Catalysis of the reaction: L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate.,L-valine:2-oxoglutarate transaminase activity,molecular_function
79822,GO:0052656,Catalysis of the reaction: L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate.,L-isoleucine:2-oxoglutarate transaminase activity,molecular_function
79823,GO:0052657,Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.,guanine phosphoribosyltransferase activity,molecular_function
79824,GO:0052658,"Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.","inositol-1,4,5-trisphosphate 5-phosphatase activity",molecular_function
79825,GO:0052659,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.","inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity",molecular_function
79826,GO:0052660,"Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.",R-lactaldehyde reductase activity,molecular_function
79827,GO:0052661,"Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+.",S-lactaldehyde reductase activity,molecular_function
79828,GO:0052662,Catalysis of the reaction: all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].,zeaxanthin epoxidase activity,molecular_function
79829,GO:0052664,Catalysis of the reaction: a primary nitroalkane + H2O + O2 = an aldehyde + H+ + H2O2 + nitrite; also converts secondary nitroalkanes to a ketone.,nitroalkane oxidase activity,molecular_function
79830,GO:0052673,Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.,prenol kinase activity,molecular_function
79831,GO:0052674,"Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.","ent-pimara-9(11),15-diene synthase activity",molecular_function
79832,GO:0052675,Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde.,3-methylbutanal reductase (NADPH) activity,molecular_function
79833,GO:0052676,Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.,3-methylbutanal reductase (NADH) activity,molecular_function
79834,GO:0052678,"Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.",levopimaradiene synthase activity,molecular_function
79835,GO:0052679,Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.,terpentetriene synthase activity,molecular_function
79836,GO:0052680,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.",epi-isozizaene synthase activity,molecular_function
79837,GO:0052681,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate.",alpha-bisabolene synthase activity,molecular_function
79838,GO:0052682,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.",epi-cedrol synthase activity,molecular_function
79839,GO:0052683,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.",(Z)-gamma-bisabolene synthase activity,molecular_function
79840,GO:0052684,Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O.,"L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity",molecular_function
79841,GO:0052686,Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA.,perillic acid-CoA ligase (AMP-forming) activity,molecular_function
79842,GO:0052689,Catalysis of the hydrolysis of a carboxylic ester bond.,carboxylic ester hydrolase activity,molecular_function
79843,GO:0052690,"Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.",trichloro-p-hydroquinone reductive dehalogenase activity,molecular_function
79844,GO:0052691,Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.,UDP-arabinopyranose mutase activity,molecular_function
79845,GO:0052692,Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose.,raffinose alpha-galactosidase activity,molecular_function
79846,GO:0052693,Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.,epoxyqueuosine reductase activity,molecular_function
79847,GO:0052694,Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O.,jasmonoyl-isoleucine-12-hydroxylase activity,molecular_function
79848,GO:0052699,"The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.",ergothioneine biosynthetic process,biological_process
79849,GO:0052700,"The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.",ergothioneine catabolic process,biological_process
79850,GO:0052702,"The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.",modified histidine catabolic process,biological_process
79851,GO:0052703,"The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid within a cell.",modified histidine biosynthetic process,biological_process
79852,GO:0052706,"Catalysis of the reaction: L-histidine + 3 S-adenosyl-L-methionine <=> 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to L-histidine to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine).",L-histidine N(alpha)-methyltransferase activity,molecular_function
79853,GO:0052712,Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.,inositol phosphosphingolipid phospholipase activity,molecular_function
79854,GO:0052713,Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.,inositol phosphorylceramide phospholipase activity,molecular_function
79855,GO:0052714,Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.,mannosyl-inositol phosphorylceramide phospholipase activity,molecular_function
79856,GO:0052716,Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.,hydroquinone:oxygen oxidoreductase activity,molecular_function
79857,GO:0052717,Catalysis of the reaction: adenosine34 in tRNA + H2O + H+ = inosine34 in tRNA + NH4+.,tRNA-specific adenosine-34 deaminase activity,molecular_function
79858,GO:0052718,A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human.,tRNA-specific adenosine-34 deaminase complex,cellular_component
79859,GO:0052719,"Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.",RNA-(apurinic or apyrimidinic site) endonuclease activity,molecular_function
79860,GO:0052720,"Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.",class II DNA-(apurinic or apyrimidinic site) endonuclease activity,molecular_function
79861,GO:0052722,Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.,fatty acid in-chain hydroxylase activity,molecular_function
79862,GO:0052723,"Catalysis of the reaction: 1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP.",inositol hexakisphosphate 1-kinase activity,molecular_function
79863,GO:0052724,"Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.",inositol hexakisphosphate 3-kinase activity,molecular_function
79864,GO:0052725,"Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H+.","inositol-1,3,4-trisphosphate 6-kinase activity",molecular_function
79865,GO:0052726,"Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H+.","inositol-1,3,4-trisphosphate 5-kinase activity",molecular_function
79866,GO:0052727,Catalysis of the reaction: all-trans-antheraxanthin = all-trans-capsanthin.,capsanthin synthase activity,molecular_function
79867,GO:0052728,Catalysis of the reaction: all-trans-violaxanthin = all-trans-capsorubin.,capsorubin synthase activity,molecular_function
79868,GO:0052729,"Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.",dimethylglycine N-methyltransferase activity,molecular_function
79869,GO:0052730,"Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.",sarcosine N-methyltransferase activity,molecular_function
79870,GO:0052731,Catalysis of the reaction: phosphocholine + H2O = choline + phosphate.,phosphocholine phosphatase activity,molecular_function
79871,GO:0052732,Catalysis of the reaction: phosphoethanolamine + H2O = ethanolamine + phosphate.,phosphoethanolamine phosphatase activity,molecular_function
79872,GO:0052733,Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+.,quinate 3-dehydrogenase (NADP+) activity,molecular_function
79873,GO:0052734,Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.,shikimate 3-dehydrogenase (NAD+) activity,molecular_function
79874,GO:0052735,Catalysis of the reaction: a cytidine in tRNA + S-adenosyl-L-methionine = an N3-methylcytidine in tRNA + H+ + S-adenosyl-L-homocysteine.,tRNA (cytidine-N3)-methyltransferase activity,molecular_function
79875,GO:0052736,Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds.,beta-glucanase activity,molecular_function
79876,GO:0052737,Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.,pyruvate dehydrogenase (quinone) activity,molecular_function
79877,GO:0052738,Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.,"oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor",molecular_function
79878,GO:0052741,"Catalysis of the reaction: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1R,5S)-carveol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",(R)-limonene 6-monooxygenase activity,molecular_function
79879,GO:0052742,Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate.,phosphatidylinositol kinase activity,molecular_function
79880,GO:0052743,Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.,inositol tetrakisphosphate phosphatase activity,molecular_function
79881,GO:0052744,Catalysis of the reaction: phosphatidyl-1D-myo-inositol monophosphate + H2O = phosphatidylinositol + phosphate.,phosphatidylinositol monophosphate phosphatase activity,molecular_function
79882,GO:0052745,Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.,inositol phosphate phosphatase activity,molecular_function
79883,GO:0052748,Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.,baicalin beta-D-glucuronidase activity,molecular_function
79884,GO:0052749,"Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.",glucose-6-phosphate dehydrogenase (coenzyme F420) activity,molecular_function
79885,GO:0052750,Catalysis of the reaction: reactive black 5 + H2O2 = oxidized reactive black 5 + 2 H2O.,versatile peroxidase activity,molecular_function
79886,GO:0052751,Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.,GDP-mannose hydrolase activity,molecular_function
79887,GO:0052753,Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420.,propan-2-ol:coenzyme F420 oxidoreductase activity,molecular_function
79888,GO:0052755,Catalysis of the reaction: oxidized coenzyme F420-(gamma-L-Glu)(n) + a quinol + H+ = reduced coenzyme F420-(gamma-L-Glu)(n) + a quinone.,coenzyme F420H2:quinone oxidoreductase activity,molecular_function
79889,GO:0052757,"Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].",chondroitin hydrolase activity,molecular_function
79890,GO:0052761,Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.,"exo-1,4-beta-D-glucosaminidase activity",molecular_function
79891,GO:0052762,"Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).",gellan lyase activity,molecular_function
79892,GO:0052763,"Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.",ulvan lyase activity,molecular_function
79893,GO:0052764,"Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.",exo-oligoalginate lyase activity,molecular_function
79894,GO:0052765,Catalysis of the reaction: 2 reduced coenzyme F420-(gamma-L-Glu)(n) + O2 = 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 H2O + 2 H+.,coenzyme F420H2 oxidase activity,molecular_function
79895,GO:0052766,"Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.","mannoside alpha-1,4-mannosidase activity",molecular_function
79896,GO:0052767,Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.,"mannosyl-oligosaccharide 1,6-alpha-mannosidase activity",molecular_function
79897,GO:0052768,Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.,"mannosyl-oligosaccharide 1,3-alpha-mannosidase activity",molecular_function
79898,GO:0052769,"Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.",beta-6-sulfate-N-acetylglucosaminidase activity,molecular_function
79899,GO:0052772,"Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.",brefeldin A esterase activity,molecular_function
79900,GO:0052773,"Catalysis of the reaction: H2O + N,N'-diacetylchitobiose = acetate + beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine.",diacetylchitobiose deacetylase activity,molecular_function
79901,GO:0052774,Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.,glucosyl-N-acetylglucosamine glucosaminidase activity,molecular_function
79902,GO:0052775,Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.,"endo-1,3-alpha-L-rhamnosidase activity",molecular_function
79903,GO:0052777,The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.,diacetylchitobiose catabolic process,biological_process
79904,GO:0052778,"The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose.",diacetylchitobiose metabolic process,biological_process
79905,GO:0052781,"The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.",chitobiose catabolic process,biological_process
79906,GO:0052784,"The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.",reuteran biosynthetic process,biological_process
79907,GO:0052785,"The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.",cellulose catabolism by endo-processive cellulases,biological_process
79908,GO:0052788,Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.,"d-4,5 unsaturated beta-glucuronyl hydrolase activity",molecular_function
79909,GO:0052791,Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain.,3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity,molecular_function
79910,GO:0052792,"Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position.",endo-xylogalacturonan hydrolase activity,molecular_function
79911,GO:0052793,"Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.",pectin acetylesterase activity,molecular_function
79912,GO:0052797,Catalysis of the reaction: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H+.,4-O-methyl-glucuronoyl methylesterase activity,molecular_function
79913,GO:0052798,"Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.","beta-galactoside alpha-2,3-sialyltransferase activity",molecular_function
79914,GO:0052799,"The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that ...",coenzyme F420-dependent bicyclic nitroimidazole catabolic process,biological_process
79915,GO:0052800,The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.,bicyclic nitroimidazole catabolic process,biological_process
79916,GO:0052803,"The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.",imidazole-containing compound metabolic process,biological_process
79917,GO:0052804,"The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.",nitroimidazole catabolic process,biological_process
79918,GO:0052805,"The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.",imidazole-containing compound catabolic process,biological_process
79919,GO:0052806,Catalysis of the reaction: 3 oxidized coenzyme F420-(gamma-L-Glu)(n) + hydrogen sulfide + 3 H2O + 2 H+ = 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite.,sulfite reductase (coenzyme F420) activity,molecular_function
79920,GO:0052807,"Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.",aflatoxin reductase (coenzyme F420) activity,molecular_function
79921,GO:0052809,"Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid.",acharan sulfate lyase activity,molecular_function
79922,GO:0052810,Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + H+.,1-phosphatidylinositol-5-kinase activity,molecular_function
79923,GO:0052811,"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + H+.",1-phosphatidylinositol-3-phosphate 4-kinase activity,molecular_function
79924,GO:0052814,Catalysis of the reaction: a medium-chain fatty aldehyde + H2O + NAD+ = a medium chain fatty acid + 2 H+ + NADH.,medium-chain fatty aldehyde dehydrogenase (NAD+) activity,molecular_function
79925,GO:0052815,Catalysis of the reaction: a medium-chain fatty acyl-CoA + H2O = a medium-chain fatty acid + CoA + H+. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acyl-CoA hydrolase activity,molecular_function
79926,GO:0052816,Catalysis of the reaction: a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H+. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acyl-CoA hydrolase activity,molecular_function
79927,GO:0052817,Catalysis of the reaction: a very long-chain fatty acyl-CoA + H2O = a very long-chain fatty acid + CoA + H+. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acyl-CoA hydrolase activity,molecular_function
79928,GO:0052820,"Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.","DNA-1,N6-ethenoadenine N-glycosylase activity",molecular_function
79929,GO:0052821,"Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.",DNA-7-methyladenine glycosylase activity,molecular_function
79930,GO:0052822,"Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.",DNA-3-methylguanine glycosylase activity,molecular_function
79931,GO:0052823,"Catalysis of the reaction: (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H+.","2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity",molecular_function
79932,GO:0052825,"Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.","inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity",molecular_function
79933,GO:0052827,Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.,inositol pentakisphosphate phosphatase activity,molecular_function
79934,GO:0052828,"Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.","inositol-3,4-bisphosphate 4-phosphatase activity",molecular_function
79935,GO:0052829,"Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.","inositol-1,3,4-trisphosphate 1-phosphatase activity",molecular_function
79936,GO:0052830,"Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.","inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity",molecular_function
79937,GO:0052831,"Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.","inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity",molecular_function
79938,GO:0052832,Catalysis of the reaction: 1D-myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.,inositol monophosphate 3-phosphatase activity,molecular_function
79939,GO:0052833,Catalysis of the reaction:1D-myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.,inositol monophosphate 4-phosphatase activity,molecular_function
79940,GO:0052834,Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.,inositol monophosphate phosphatase activity,molecular_function
79941,GO:0052835,"Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H+.","inositol-3,4,6-trisphosphate 1-kinase activity",molecular_function
79942,GO:0052836,Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol pentakisphosphate = ADP + 5-triphospho-1D-myo-inositol pentakisphosphate.,inositol 5-diphosphate pentakisphosphate 5-kinase activity,molecular_function
79943,GO:0052837,"The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.",thiazole biosynthetic process,biological_process
79944,GO:0052838,"The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.",thiazole metabolic process,biological_process
79945,GO:0052839,Catalysis of the reaction: ATP + diphospho-1D-myo-inositol tetrakisphosphate = ADP + bis(diphospho)-1D-myo-inositol trisphosphate.,diphosphoinositol tetrakisphosphate kinase activity,molecular_function
79946,GO:0052840,Catalysis of the reaction: diphospho-1D-myo-inositol tetrakisphosphate + H2O = 1D-myo-inositol pentakisphosphate + phosphate.,inositol diphosphate tetrakisphosphate diphosphatase activity,molecular_function
79947,GO:0052841,Catalysis of the reaction: bisdiphospho-1D-myo-inositol tetrakisphosphate + H2O = diphospho-1D-myo-inositol pentakisphosphate + phosphate.,inositol bisdiphosphate tetrakisphosphate diphosphatase activity,molecular_function
79948,GO:0052842,Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.,inositol diphosphate pentakisphosphate diphosphatase activity,molecular_function
79949,GO:0052843,"Catalysis of the reaction: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.","inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity",molecular_function
79950,GO:0052844,"Catalysis of the reaction: 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.","inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity",molecular_function
79951,GO:0052845,"Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + H+.","inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity",molecular_function
79952,GO:0052846,"Catalysis of the reaction: 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.","inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity",molecular_function
79953,GO:0052847,"Catalysis of the reaction: 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+.","inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity",molecular_function
79954,GO:0052848,"Catalysis of the reaction: 3,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H+.","inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity",molecular_function
79955,GO:0052849,Catalysis of the reaction: 2 NADP+ + tetrahydrocurcumin = curcumin + 2 H+ + 2 NADPH.,curcumin reductase (NADP+) activity,molecular_function
79956,GO:0052851,Catalysis of the reaction: 2 a Fe(II)-siderophore + NADP+ + H+ = 2 a Fe(III)-siderophore + NADPH.,ferric-chelate reductase (NADPH) activity,molecular_function
79957,GO:0052855,"Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + H+ + NAD(P)H + phosphate.",ADP-dependent NAD(P)H-hydrate dehydratase activity,molecular_function
79958,GO:0052856,Catalysis of the reactions: (6R)-NADHX = (6S)-NADHX and (6R)-NADPHX = (6S)-NADPHX.,NAD(P)HX epimerase activity,molecular_function
79959,GO:0052861,"Catalysis of the endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3. Substrates include laminarin, lichenin and cereal D-glucans.","endo-1,3(4)-beta-glucanase activity",molecular_function
79960,GO:0052866,Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.,phosphatidylinositol phosphate phosphatase activity,molecular_function
79961,GO:0052867,"Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.","phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity",molecular_function
79962,GO:0052868,"Catalysis of the reaction: D-beta-lysine + L-lysyl-[protein] + ATP = N6-((3R)-3,6-diaminohexanoyl)-L-lysyl-[protein] + AMP + diphosphate + H+n. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.",protein-lysine lysyltransferase activity,molecular_function
79963,GO:0052869,"Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. (5Z,8Z,11Z,14Z)-icosatetraenoic acid is also known as arachidonic acid is also and 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate as 20-HETE.",arachidonate omega-hydroxylase activity,molecular_function
79964,GO:0052871,Catalysis of the reaction: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,alpha-tocopherol omega-hydroxylase activity,molecular_function
79965,GO:0052873,Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.,FMN reductase (NADPH) activity,molecular_function
79966,GO:0052874,Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.,FMN reductase (NADH) activity,molecular_function
79967,GO:0052875,Catalysis of the reaction: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+. This reaction can utilize NADH and NADPH.,riboflavin reductase [NAD(P)H] activity,molecular_function
79968,GO:0052876,Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin].,methylamine dehydrogenase (amicyanin) activity,molecular_function
79969,GO:0052877,Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.,"oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor",molecular_function
79970,GO:0052878,"Catalysis of the reaction: O2 + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.",linoleate 8R-lipoxygenase activity,molecular_function
79971,GO:0052879,"Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate.","9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity",molecular_function
79972,GO:0052880,"Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.","oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor",molecular_function
79973,GO:0052881,"Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O2 = 3,4-dihydroxyphenylacetate + FAD + H+ + H2O.",4-hydroxyphenylacetate 3-monooxygenase activity,molecular_function
79974,GO:0052882,Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.,"oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor",molecular_function
79975,GO:0052883,Catalysis of the reaction: L-tyrosine = NH4 + trans-4-coumarate.,tyrosine ammonia-lyase activity,molecular_function
79976,GO:0052884,Catalysis of the reaction: H2O + all-trans-retinyl palmitate = 11-cis-retinol + H+ + palmitate.,"all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity",molecular_function
79977,GO:0052885,Catalysis of the reaction: H2O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.,"all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity",molecular_function
79978,GO:0052890,Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.,"oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor",molecular_function
79979,GO:0052891,Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.,aliphatic (S)-hydroxynitrile lyase activity,molecular_function
79980,GO:0052892,Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.,aromatic (S)-hydroxynitrile lyase activity,molecular_function
79981,GO:0052897,"Catalysis of the reaction: N(8)-acetylspermidine + O2 + H2O = 4-acetamidobutanal + propane-1,3-diamine + H2O2. Also active with N(1)-acetylspermine, weak activity with N(1),N(12)- diacetylspermine.","N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity",molecular_function
79982,GO:0052900,"Catalysis of the reaction: spermidine + O2 + H2O = 4-aminobutanal + propane-1,3-diamine + H2O2. Weak activity on N(1)-acetylspermine and spermine.","polyamine oxidase (propane-1,3-diamine-forming) activity",molecular_function
79983,GO:0052901,Catalysis of the reaction: H2O + O2 + spermine = 3-aminopropanal + H2O2 + spermidine. Weak activity with N(1)-acetylspermine. The Arabidopsis thaliana enzyme converts norspermine to norspermidine.,spermine oxidase activity,molecular_function
79984,GO:0052903,"Catalysis of the reaction: N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2. Also converts N(1)-acetylspermidine to putrescine, and N(1),N(12)-diacetylspermine to N(1)-acetylspermidine.",N(1)-acetylpolyamine oxidase activity,molecular_function
79985,GO:0052905,Catalysis of the reaction: guanosine9 in tRNA + S-adenosyl-L-methionine = H+ + N1-methylguanosine9 in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanosine(9)-N1)-methyltransferase activity,molecular_function
79986,GO:0052906,Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanine(37)-N1)-methyltransferase activity,molecular_function
79987,GO:0052907,Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.,23S rRNA (adenine(1618)-N(6))-methyltransferase activity,molecular_function
79988,GO:0052908,Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.,16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity,molecular_function
79989,GO:0052909,Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.,18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity,molecular_function
79990,GO:0052910,Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.,23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity,molecular_function
79991,GO:0052911,Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.,23S rRNA (guanine(745)-N(1))-methyltransferase activity,molecular_function
79992,GO:0052912,Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.,23S rRNA (guanine(748)-N(1))-methyltransferase activity,molecular_function
79993,GO:0052913,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.,16S rRNA (guanine(966)-N(2))-methyltransferase activity,molecular_function
79994,GO:0052914,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine.,16S rRNA (guanine(1207)-N(2))-methyltransferase activity,molecular_function
79995,GO:0052915,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.,23S rRNA (guanine(2445)-N(2))-methyltransferase activity,molecular_function
79996,GO:0052916,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine.,23S rRNA (guanine(1835)-N(2))-methyltransferase activity,molecular_function
79997,GO:0052917,"Catalysis of the reaction: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosp...","dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity",molecular_function
79998,GO:0052918,"Catalysis of the reaction: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-bet...","dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity",molecular_function
79999,GO:0052919,Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.,aliphatic (R)-hydroxynitrile lyase activity,molecular_function
80000,GO:0052922,"Catalysis of the reaction: 2 isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate = all-trans-hexaprenyl diphosphate + 2 diphosphate.",hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity,molecular_function
80001,GO:0052923,Catalysis of the reaction: 7 isopentenyl diphosphate + (2E)-geranyl diphosphate = all-trans-nonaprenyl diphosphate + 7 diphosphate.,all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity,molecular_function
80002,GO:0052924,"Catalysis of the reaction: 5 isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate = all-trans-nonaprenyl diphosphate + 5 diphosphate.",all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity,molecular_function
80003,GO:0052925,"Catalysis of the reaction: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H+.","dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity",molecular_function
80004,GO:0052926,"Catalysis of the reaction: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-tra...","dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity",molecular_function
80005,GO:0052927,Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' CC end + 2 diphosphate.,CC tRNA cytidylyltransferase activity,molecular_function
80006,GO:0052929,Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.,ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity,molecular_function
80007,GO:0052933,Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.,alcohol dehydrogenase (cytochrome c(L)) activity,molecular_function
80008,GO:0052934,Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.,alcohol dehydrogenase (cytochrome c) activity,molecular_function
80009,GO:0055001,"The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.",muscle cell development,biological_process
80010,GO:0055002,"The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.",striated muscle cell development,biological_process
80011,GO:0055003,"The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.",cardiac myofibril assembly,biological_process
80012,GO:0055004,"The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.",atrial cardiac myofibril assembly,biological_process
80013,GO:0055005,"The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.",ventricular cardiac myofibril assembly,biological_process
80014,GO:0055006,"The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.",cardiac cell development,biological_process
80015,GO:0055007,The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.,cardiac muscle cell differentiation,biological_process
80016,GO:0055008,The process in which the anatomical structures of cardiac muscle tissue are generated and organized.,cardiac muscle tissue morphogenesis,biological_process
80017,GO:0055009,The process in which the anatomical structure of cardiac atrium muscle is generated and organized.,atrial cardiac muscle tissue morphogenesis,biological_process
80018,GO:0055010,The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.,ventricular cardiac muscle tissue morphogenesis,biological_process
80019,GO:0055011,The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.,atrial cardiac muscle cell differentiation,biological_process
80020,GO:0055012,The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.,ventricular cardiac muscle cell differentiation,biological_process
80021,GO:0055013,"The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.",cardiac muscle cell development,biological_process
80022,GO:0055014,"The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.",atrial cardiac muscle cell development,biological_process
80023,GO:0055015,"The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.",ventricular cardiac muscle cell development,biological_process
80024,GO:0055016,"The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.",hypochord development,biological_process
80025,GO:0055017,"The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.",cardiac muscle tissue growth,biological_process
80026,GO:0055018,"Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.",regulation of cardiac muscle fiber development,biological_process
80027,GO:0055019,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.",negative regulation of cardiac muscle fiber development,biological_process
80028,GO:0055020,"Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.",positive regulation of cardiac muscle fiber development,biological_process
80029,GO:0055021,"Any process that modulates the frequency, rate or extent of cardiac muscle growth.",regulation of cardiac muscle tissue growth,biological_process
80030,GO:0055022,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.",negative regulation of cardiac muscle tissue growth,biological_process
80031,GO:0055023,"Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.",positive regulation of cardiac muscle tissue growth,biological_process
80032,GO:0055024,"Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.",regulation of cardiac muscle tissue development,biological_process
80033,GO:0055025,"Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.",positive regulation of cardiac muscle tissue development,biological_process
80034,GO:0055026,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.",negative regulation of cardiac muscle tissue development,biological_process
80035,GO:0055028,Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.,cortical microtubule,cellular_component
80036,GO:0055029,"A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.",nuclear DNA-directed RNA polymerase complex,cellular_component
80037,GO:0055034,"The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.",Bolwig's organ development,biological_process
80038,GO:0055035,The lipid bilayer membrane of any thylakoid within a plastid.,plastid thylakoid membrane,cellular_component
80039,GO:0055036,The lipid bilayer surrounding a virion.,virion membrane,cellular_component
80040,GO:0055037,"An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.",recycling endosome,cellular_component
80041,GO:0055038,The lipid bilayer surrounding a recycling endosome.,recycling endosome membrane,cellular_component
80042,GO:0055039,"A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft.",trichocyst,cellular_component
80043,GO:0055040,"Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella.",periplasmic flagellum,cellular_component
80044,GO:0055041,Catalysis of the reaction: cyclopentanol + NAD+ = cyclopentanone + H+ + NADH.,cyclopentanol dehydrogenase activity,molecular_function
80045,GO:0055044,The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.,symplast,cellular_component
80046,GO:0055045,The process in which the antipodal cells undergo programmed cell death.,antipodal cell degeneration,biological_process
80047,GO:0055046,"The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.",microgametogenesis,biological_process
80048,GO:0055047,The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.,generative cell mitosis,biological_process
80049,GO:0055048,"The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array...",anastral spindle assembly,biological_process
80050,GO:0055051,"A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.","ATP-binding cassette (ABC) transporter complex, integrated substrate binding",cellular_component
80051,GO:0055052,"A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of...","ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing",cellular_component
80052,GO:0055053,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.,mannose:proton symporter activity,molecular_function
80053,GO:0055054,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.,fructose:proton symporter activity,molecular_function
80054,GO:0055056,Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.,D-glucose transmembrane transporter activity,molecular_function
80055,GO:0055057,The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.,neuroblast division,biological_process
80056,GO:0055058,The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells.,symmetric neuroblast division,biological_process
80057,GO:0055059,The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.,asymmetric neuroblast division,biological_process
80058,GO:0055060,Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.,asymmetric neuroblast division resulting in ganglion mother cell formation,biological_process
80059,GO:0055062,Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.,phosphate ion homeostasis,biological_process
80060,GO:0055063,Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.,sulfate ion homeostasis,biological_process
80061,GO:0055064,Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.,chloride ion homeostasis,biological_process
80062,GO:0055070,Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.,copper ion homeostasis,biological_process
80063,GO:0055071,Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.,manganese ion homeostasis,biological_process
80064,GO:0055074,Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.,calcium ion homeostasis,biological_process
80065,GO:0055075,Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.,potassium ion homeostasis,biological_process
80066,GO:0055077,A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.,gap junction hemi-channel activity,molecular_function
80067,GO:0055078,Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.,sodium ion homeostasis,biological_process
80068,GO:0055080,Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.,monoatomic cation homeostasis,biological_process
80069,GO:0055081,Any process involved in the maintenance of an internal steady state of monoatomic anions within an organism or cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom.,monoatomic anion homeostasis,biological_process
80070,GO:0055082,A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell.,intracellular chemical homeostasis,biological_process
80071,GO:0055085,"The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.",transmembrane transport,biological_process
80072,GO:0055086,"The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.",nucleobase-containing small molecule metabolic process,biological_process
80073,GO:0055087,A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.,Ski complex,cellular_component
80074,GO:0055088,Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.,lipid homeostasis,biological_process
80075,GO:0055089,Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.,fatty acid homeostasis,biological_process
80076,GO:0055090,Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.,acylglycerol homeostasis,biological_process
80077,GO:0055091,Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.,phospholipid homeostasis,biological_process
80078,GO:0055092,Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.,sterol homeostasis,biological_process
80079,GO:0055093,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.",response to hyperoxia,biological_process
80080,GO:0055094,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.",response to lipoprotein particle,biological_process
80081,GO:0055095,The series of molecular signals mediated by the detection of a lipoprotein particle.,lipoprotein particle mediated signaling,biological_process
80082,GO:0055096,The series of molecular signals mediated by the detection of low-density lipoprotein particle.,low-density lipoprotein particle mediated signaling,biological_process
80083,GO:0055097,The series of molecular signals mediated by the detection of high density lipoprotein particle.,high density lipoprotein particle mediated signaling,biological_process
80084,GO:0055100,"Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.",adiponectin binding,molecular_function
80085,GO:0055102,"Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.",lipase inhibitor activity,molecular_function
80086,GO:0055103,Binds to and modulates the activity of a ligase.,ligase regulator activity,molecular_function
80087,GO:0055104,"Binds to and stops, prevents or reduces the activity of a ligase.",ligase inhibitor activity,molecular_function
80088,GO:0055105,"Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.",ubiquitin-protein transferase inhibitor activity,molecular_function
80089,GO:0055106,"Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.",ubiquitin-protein transferase regulator activity,molecular_function
80090,GO:0055107,"The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.",Golgi to secretory granule transport,biological_process
80091,GO:0055109,The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.,invagination involved in gastrulation with mouth forming second,biological_process
80092,GO:0055110,The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.,involution involved in gastrulation with mouth forming second,biological_process
80093,GO:0055111,The migration of individual cells into the embryo involved in deuterostomic gastrulation.,ingression involved in gastrulation with mouth forming second,biological_process
80094,GO:0055113,The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.,epiboly involved in gastrulation with mouth forming second,biological_process
80095,GO:0055115,"The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic...",entry into diapause,biological_process
80096,GO:0055116,"The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",entry into reproductive diapause,biological_process
80097,GO:0055117,"Any process that modulates the frequency, rate or extent of cardiac muscle contraction.",regulation of cardiac muscle contraction,biological_process
80098,GO:0055118,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.",negative regulation of cardiac muscle contraction,biological_process
80099,GO:0055119,The process in which the extent of cardiac muscle contraction is reduced.,relaxation of cardiac muscle,biological_process
80100,GO:0055120,"A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.",striated muscle dense body,cellular_component
80101,GO:0055121,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2.",response to high fluence blue light stimulus by blue high-fluence system,biological_process
80102,GO:0055122,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.",response to very low light intensity stimulus,biological_process
80103,GO:0055123,"The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",digestive system development,biological_process
80104,GO:0055127,The transmission of vibrations via ossicles to the inner ear.,vibrational conductance of sound to the inner ear,biological_process
80105,GO:0055129,"The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.",L-proline biosynthetic process,biological_process
80106,GO:0055130,The chemical reactions and pathways resulting in the breakdown of D-alanine.,D-alanine catabolic process,biological_process
80107,GO:0055131,"Binding to a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.",C3HC4-type RING finger domain binding,molecular_function
80108,GO:0060001,"A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.",minus-end directed microfilament motor activity,molecular_function
80109,GO:0060002,"A motor activity that generates movement along a microfilament towards the plus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.",plus-end directed microfilament motor activity,molecular_function
80110,GO:0060003,The directed movement of copper ions out of a cell or organelle.,copper ion export,biological_process
80111,GO:0060004,An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.,reflex,biological_process
80112,GO:0060005,A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.,vestibular reflex,biological_process
80113,GO:0060006,A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.,angular vestibuloocular reflex,biological_process
80114,GO:0060007,A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.,linear vestibuloocular reflex,biological_process
80115,GO:0060008,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.,Sertoli cell differentiation,biological_process
80116,GO:0060009,"The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.",Sertoli cell development,biological_process
80117,GO:0060010,The process in which the cellular identity of Sertoli cells is acquired and determined.,Sertoli cell fate commitment,biological_process
80118,GO:0060011,"The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.",Sertoli cell proliferation,biological_process
80119,GO:0060012,"The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of ...","synaptic transmission, glycinergic",biological_process
80120,GO:0060013,A reflex process in which an animal immediately tries to turn over after being placed in a supine position.,righting reflex,biological_process
80121,GO:0060014,"The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.",granulosa cell differentiation,biological_process
80122,GO:0060015,The cell fate commitment of precursor cells that will become granulosa cells.,granulosa cell fate commitment,biological_process
80123,GO:0060016,"The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.",granulosa cell development,biological_process
80124,GO:0060017,"The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.",parathyroid gland development,biological_process
80125,GO:0060018,The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.,astrocyte fate commitment,biological_process
80126,GO:0060019,"The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.",radial glial cell differentiation,biological_process
80127,GO:0060020,"The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.",Bergmann glial cell differentiation,biological_process
80128,GO:0060021,The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.,roof of mouth development,biological_process
80129,GO:0060022,"The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.",hard palate development,biological_process
80130,GO:0060023,"The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.",soft palate development,biological_process
80131,GO:0060024,"Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.",rhythmic synaptic transmission,biological_process
80132,GO:0060025,"Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.",regulation of synaptic activity,biological_process
80133,GO:0060026,The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.,convergent extension,biological_process
80134,GO:0060027,"The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.",convergent extension involved in gastrulation,biological_process
80135,GO:0060028,The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.,convergent extension involved in axis elongation,biological_process
80136,GO:0060029,The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.,convergent extension involved in organogenesis,biological_process
80137,GO:0060030,The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.,dorsal convergence,biological_process
80138,GO:0060031,The interdigitation of cells along the mediolateral axis during gastrulation.,mediolateral intercalation,biological_process
80139,GO:0060032,The developmental process in which the structure of the notochord is destroyed in an embryo.,notochord regression,biological_process
80140,GO:0060033,The developmental process in which an anatomical structure is destroyed as a part of its normal progression.,anatomical structure regression,biological_process
80141,GO:0060034,The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.,notochord cell differentiation,biological_process
80142,GO:0060035,"The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",notochord cell development,biological_process
80143,GO:0060036,The assembly and arrangement of a vacuole within a cell of the notochord.,notochord cell vacuolation,biological_process
80144,GO:0060037,"The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal cle...",pharyngeal system development,biological_process
80145,GO:0060038,The expansion of a cardiac muscle cell population by cell division.,cardiac muscle cell proliferation,biological_process
80146,GO:0060039,"The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.",pericardium development,biological_process
80147,GO:0060040,"The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.",retinal bipolar neuron differentiation,biological_process
80148,GO:0060041,"The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.",retina development in camera-type eye,biological_process
80149,GO:0060042,The process in which the anatomical structure of the retina is generated and organized.,retina morphogenesis in camera-type eye,biological_process
80150,GO:0060043,"Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.",regulation of cardiac muscle cell proliferation,biological_process
80151,GO:0060044,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.",negative regulation of cardiac muscle cell proliferation,biological_process
80152,GO:0060045,"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.",positive regulation of cardiac muscle cell proliferation,biological_process
80153,GO:0060046,"Any process that modulates the frequency, rate or extent of the acrosome reaction.",regulation of acrosome reaction,biological_process
80154,GO:0060047,The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.,heart contraction,biological_process
80155,GO:0060048,Muscle contraction of cardiac muscle tissue.,cardiac muscle contraction,biological_process
80156,GO:0060052,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.",neurofilament cytoskeleton organization,biological_process
80157,GO:0060053,Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.,neurofilament cytoskeleton,cellular_component
80158,GO:0060054,"Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.",positive regulation of epithelial cell proliferation involved in wound healing,biological_process
80159,GO:0060055,"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.",angiogenesis involved in wound healing,biological_process
80160,GO:0060056,The tissue remodeling that removes differentiated mammary epithelia during weaning.,mammary gland involution,biological_process
80161,GO:0060057,Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.,apoptotic process involved in mammary gland involution,biological_process
80162,GO:0060058,"Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.",positive regulation of apoptotic process involved in mammary gland involution,biological_process
80163,GO:0060059,The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.,embryonic retina morphogenesis in camera-type eye,biological_process
80164,GO:0060060,The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage.,post-embryonic retina morphogenesis in camera-type eye,biological_process
80165,GO:0060061,Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.,Spemann organizer formation,biological_process
80166,GO:0060062,Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.,Spemann organizer formation at the dorsal lip of the blastopore,biological_process
80167,GO:0060063,Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.,Spemann organizer formation at the embryonic shield,biological_process
80168,GO:0060064,Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.,Spemann organizer formation at the anterior end of the primitive streak,biological_process
80169,GO:0060065,"The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.",uterus development,biological_process
80170,GO:0060066,"The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.",oviduct development,biological_process
80171,GO:0060067,"The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.",cervix development,biological_process
80172,GO:0060068,"The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.",vagina development,biological_process
80173,GO:0060069,The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.,"Wnt signaling pathway, regulating spindle positioning",biological_process
80174,GO:0060070,"A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger ch...",canonical Wnt signaling pathway,biological_process
80175,GO:0060071,"A type of non-canonical Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the activation small G proteins such as Rho, Rac, and Cdc42 which, in turn activate effectors, including C-Jun N-terminal kinase (JNK) and Rho kinase (Rok). The signaling ends with change in the transcription of target genes and/or reorganisation of the cytoskeleton.","Wnt signaling pathway, planar cell polarity pathway",biological_process
80176,GO:0060072,Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) i...,large conductance calcium-activated potassium channel activity,molecular_function
80177,GO:0060073,The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.,micturition,biological_process
80178,GO:0060074,The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.,synapse maturation,biological_process
80179,GO:0060075,"Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.",regulation of resting membrane potential,biological_process
80180,GO:0060076,A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.,excitatory synapse,cellular_component
80181,GO:0060077,A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.,inhibitory synapse,cellular_component
80182,GO:0060078,Any process that modulates the potential difference across a post-synaptic membrane.,regulation of postsynaptic membrane potential,biological_process
80183,GO:0060079,A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.,excitatory postsynaptic potential,biological_process
80184,GO:0060080,A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.,inhibitory postsynaptic potential,biological_process
80185,GO:0060081,"The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.",membrane hyperpolarization,biological_process
80186,GO:0060082,The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.,eye blink reflex,biological_process
80187,GO:0060083,The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.,smooth muscle contraction involved in micturition,biological_process
80188,GO:0060084,The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.,synaptic transmission involved in micturition,biological_process
80189,GO:0060085,A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.,smooth muscle relaxation of the bladder outlet,biological_process
80190,GO:0060086,Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.,circadian temperature homeostasis,biological_process
80191,GO:0060087,"A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.",relaxation of vascular associated smooth muscle,biological_process
80192,GO:0060088,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.",auditory receptor cell stereocilium organization,biological_process
80193,GO:0060089,A compound molecular function in which an effector function is controlled by one or more regulatory components.,molecular transducer activity,molecular_function
80194,GO:0060090,"The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.",molecular adaptor activity,molecular_function
80195,GO:0060091,A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.,kinocilium,cellular_component
80196,GO:0060092,"Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","regulation of synaptic transmission, glycinergic",biological_process
80197,GO:0060093,"Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","negative regulation of synaptic transmission, glycinergic",biological_process
80198,GO:0060094,"Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","positive regulation of synaptic transmission, glycinergic",biological_process
80199,GO:0060095,"Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","zinc potentiation of synaptic transmission, glycinergic",biological_process
80200,GO:0060096,"The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.","serotonin secretion, neurotransmission",biological_process
80201,GO:0060097,"The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.","cytoskeletal rearrangement involved in phagocytosis, engulfment",biological_process
80202,GO:0060098,"The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.","membrane reorganization involved in phagocytosis, engulfment",biological_process
80203,GO:0060099,"Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.","regulation of phagocytosis, engulfment",biological_process
80204,GO:0060100,"Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.","positive regulation of phagocytosis, engulfment",biological_process
80205,GO:0060101,"Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.","negative regulation of phagocytosis, engulfment",biological_process
80206,GO:0060102,"A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.",cuticular extracellular matrix,cellular_component
80207,GO:0060104,"An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans.",surface coat of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80208,GO:0060105,A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans.,epicuticle of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80209,GO:0060106,"The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.",cortical layer of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80210,GO:0060107,The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present.,annuli extracellular matrix,cellular_component
80211,GO:0060108,"The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.",annular furrow extracellular matrix,cellular_component
80212,GO:0060109,"The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.",medial layer of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80213,GO:0060110,"The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal lay...",basal layer of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80214,GO:0060111,"Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.",alae of collagen and cuticulin-based cuticle extracellular matrix,cellular_component
80215,GO:0060112,The process which controls the timing of the type of sexual cycle seen in female mammals.,generation of ovulation cycle rhythm,biological_process
80216,GO:0060113,"The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.",inner ear receptor cell differentiation,biological_process
80217,GO:0060114,The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.,vestibular receptor cell differentiation,biological_process
80218,GO:0060115,The process in which a cell becomes committed to become a vestibular receptor cell.,vestibular receptor cell fate commitment,biological_process
80219,GO:0060116,Any process that alters the size or shape of a vestibular receptor cell.,vestibular receptor cell morphogenesis,biological_process
80220,GO:0060117,"The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",auditory receptor cell development,biological_process
80221,GO:0060118,"The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",vestibular receptor cell development,biological_process
80222,GO:0060119,"The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",inner ear receptor cell development,biological_process
80223,GO:0060120,The process in which a cell becomes committed to become an inner ear receptor cell.,inner ear receptor cell fate commitment,biological_process
80224,GO:0060121,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells.",vestibular receptor cell stereocilium organization,biological_process
80225,GO:0060122,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.",inner ear receptor cell stereocilium organization,biological_process
80226,GO:0060123,"Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.",regulation of growth hormone secretion,biological_process
80227,GO:0060124,"Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.",positive regulation of growth hormone secretion,biological_process
80228,GO:0060125,"Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.",negative regulation of growth hormone secretion,biological_process
80229,GO:0060126,"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.",somatotropin secreting cell differentiation,biological_process
80230,GO:0060127,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.,prolactin secreting cell differentiation,biological_process
80231,GO:0060128,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.,corticotropin hormone secreting cell differentiation,biological_process
80232,GO:0060129,"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.",thyroid-stimulating hormone-secreting cell differentiation,biological_process
80233,GO:0060130,"The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.",thyroid-stimulating hormone-secreting cell development,biological_process
80234,GO:0060131,"The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.",corticotropin hormone secreting cell development,biological_process
80235,GO:0060132,"The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.",prolactin secreting cell development,biological_process
80236,GO:0060133,"The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.",somatotropin secreting cell development,biological_process
80237,GO:0060134,The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.,prepulse inhibition,biological_process
80238,GO:0060135,A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.,maternal process involved in female pregnancy,biological_process
80239,GO:0060136,A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.,embryonic process involved in female pregnancy,biological_process
80240,GO:0060137,A reproductive process occurring in the mother that results in birth.,maternal process involved in parturition,biological_process
80241,GO:0060138,A reproductive process occurring in the fetus that results in birth.,fetal process involved in parturition,biological_process
80242,GO:0060141,"A process in which a symbiont initiates, promotes, or enhances the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual host cells. Syncytia are produced by viruses that are able to fuse directly at the cell surface without requiring endocytosis.",symbiont-mediated induction of syncytium formation,biological_process
80243,GO:0060142,"Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.",regulation of syncytium formation by plasma membrane fusion,biological_process
80244,GO:0060143,"Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.",positive regulation of syncytium formation by plasma membrane fusion,biological_process
80245,GO:0060147,"Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.",regulation of post-transcriptional gene silencing,biological_process
80246,GO:0060148,"Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.",positive regulation of post-transcriptional gene silencing,biological_process
80247,GO:0060149,"Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.",negative regulation of post-transcriptional gene silencing,biological_process
80248,GO:0060151,"Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.",peroxisome localization,biological_process
80249,GO:0060152,"The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.",microtubule-based peroxisome localization,biological_process
80250,GO:0060155,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.",platelet dense granule organization,biological_process
80251,GO:0060156,"A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.",milk ejection reflex,biological_process
80252,GO:0060157,"The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.",urinary bladder development,biological_process
80253,GO:0060158,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating dopamine receptor signaling pathway,biological_process
80254,GO:0060159,"Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.",regulation of dopamine receptor signaling pathway,biological_process
80255,GO:0060160,"Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.",negative regulation of dopamine receptor signaling pathway,biological_process
80256,GO:0060161,"Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.",positive regulation of dopamine receptor signaling pathway,biological_process
80257,GO:0060162,"Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway.",negative regulation of phospholipase C-activating dopamine receptor signaling pathway,biological_process
80258,GO:0060163,"The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.",subpallium neuron fate commitment,biological_process
80259,GO:0060164,The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.,regulation of timing of neuron differentiation,biological_process
80260,GO:0060165,The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.,regulation of timing of subpallium neuron differentiation,biological_process
80261,GO:0060166,"The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.",olfactory pit development,biological_process
80262,GO:0060167,"Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.",regulation of adenosine receptor signaling pathway,biological_process
80263,GO:0060168,"Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.",positive regulation of adenosine receptor signaling pathway,biological_process
80264,GO:0060169,"Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.",negative regulation of adenosine receptor signaling pathway,biological_process
80265,GO:0060170,The portion of the plasma membrane surrounding a cilium.,ciliary membrane,cellular_component
80266,GO:0060171,The portion of the plasma membrane surrounding a stereocilium.,stereocilium membrane,cellular_component
80267,GO:0060172,The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.,astral microtubule depolymerization,biological_process
80268,GO:0060173,"The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.",limb development,biological_process
80269,GO:0060174,"The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.",limb bud formation,biological_process
80270,GO:0060175,Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.,brain-derived neurotrophic factor receptor activity,molecular_function
80271,GO:0060176,"Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.",regulation of aggregation involved in sorocarp development,biological_process
80272,GO:0060177,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.",regulation of angiotensin metabolic process,biological_process
80273,GO:0060178,Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.,regulation of exocyst localization,biological_process
80274,GO:0060179,The specific behavior of a male organism that is associated with reproduction.,male mating behavior,biological_process
80275,GO:0060180,The specific behavior of a female organism that is associated with reproduction.,female mating behavior,biological_process
80276,GO:0060182,Combining with the peptide apelin to initiate a change in cell activity.,apelin receptor activity,molecular_function
80277,GO:0060183,"A G protein-coupled receptor signaling pathway initiated by apelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",apelin receptor signaling pathway,biological_process
80278,GO:0060184,The process in which a cell switches cell cycle mode.,cell cycle switching,biological_process
80279,GO:0060185,The opening and spreading out of the outer ear.,outer ear unfolding,biological_process
80280,GO:0060186,The growth of the outer ear.,outer ear emergence,biological_process
80281,GO:0060187,Either of two different areas at opposite ends of an axis of a cell.,cell pole,cellular_component
80282,GO:0060188,"Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.",regulation of protein desumoylation,biological_process
80283,GO:0060189,"Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.",positive regulation of protein desumoylation,biological_process
80284,GO:0060190,"Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.",negative regulation of protein desumoylation,biological_process
80285,GO:0060192,"Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.",negative regulation of lipase activity,biological_process
80286,GO:0060193,"Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.",positive regulation of lipase activity,biological_process
80287,GO:0060194,"Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.",regulation of antisense RNA transcription,biological_process
80288,GO:0060195,"Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.",negative regulation of antisense RNA transcription,biological_process
80289,GO:0060196,"Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.",positive regulation of antisense RNA transcription,biological_process
80290,GO:0060197,"The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.",cloacal septation,biological_process
80291,GO:0060198,A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release.,clathrin-sculpted vesicle,cellular_component
80292,GO:0060199,A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.,clathrin-sculpted glutamate transport vesicle,cellular_component
80293,GO:0060200,A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine.,clathrin-sculpted acetylcholine transport vesicle,cellular_component
80294,GO:0060201,The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.,clathrin-sculpted acetylcholine transport vesicle membrane,cellular_component
80295,GO:0060202,The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle.,clathrin-sculpted acetylcholine transport vesicle lumen,cellular_component
80296,GO:0060203,The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle.,clathrin-sculpted glutamate transport vesicle membrane,cellular_component
80297,GO:0060204,The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.,clathrin-sculpted glutamate transport vesicle lumen,cellular_component
80298,GO:0060205,The volume enclosed by a cytoplasmic vesicle.,cytoplasmic vesicle lumen,cellular_component
80299,GO:0060206,"The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.",estrous cycle phase,biological_process
80300,GO:0060207,The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.,diestrus,biological_process
80301,GO:0060208,The estrous cycle phase in which there is heightened follicular activity.,proestrus,biological_process
80302,GO:0060209,The estrous cycle phase in which a female is sexually receptive.,estrus,biological_process
80303,GO:0060210,The estrous cycle phase in which there is subsiding follicular function.,metestrus,biological_process
80304,GO:0060211,"Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.",regulation of nuclear-transcribed mRNA poly(A) tail shortening,biological_process
80305,GO:0060212,"Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.",negative regulation of nuclear-transcribed mRNA poly(A) tail shortening,biological_process
80306,GO:0060213,"Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.",positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,biological_process
80307,GO:0060214,"Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.",endocardium formation,biological_process
80308,GO:0060215,"A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.",primitive hemopoiesis,biological_process
80309,GO:0060216,"A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continuously provide erythroid, myeloid and lymphoid lineages throughout adulthood.",definitive hemopoiesis,biological_process
80310,GO:0060217,The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.,hemangioblast cell differentiation,biological_process
80311,GO:0060218,The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.,hematopoietic stem cell differentiation,biological_process
80312,GO:0060219,The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.,camera-type eye photoreceptor cell differentiation,biological_process
80313,GO:0060220,The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.,camera-type eye photoreceptor cell fate commitment,biological_process
80314,GO:0060221,The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.,retinal rod cell differentiation,biological_process
80315,GO:0060222,Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.,regulation of retinal cone cell fate commitment,biological_process
80316,GO:0060223,The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.,retinal rod cell fate commitment,biological_process
80317,GO:0060224,Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.,regulation of retinal rod cell fate commitment,biological_process
80318,GO:0060225,Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.,positive regulation of retinal rod cell fate commitment,biological_process
80319,GO:0060226,Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.,negative regulation of retinal cone cell fate commitment,biological_process
80320,GO:0060228,Binds to and increases the activity of phosphatidylcholine-sterol O-acyltransferase.,phosphatidylcholine-sterol O-acyltransferase activator activity,molecular_function
80321,GO:0060229,"Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.",lipase activator activity,molecular_function
80322,GO:0060230,"Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.",lipoprotein lipase activator activity,molecular_function
80323,GO:0060231,"A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.",mesenchymal to epithelial transition,biological_process
80324,GO:0060232,The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.,delamination,biological_process
80325,GO:0060233,The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet.,oenocyte delamination,biological_process
80326,GO:0060234,The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.,neuroblast delamination,biological_process
80327,GO:0060235,Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.,lens induction in camera-type eye,biological_process
80328,GO:0060236,"Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.",regulation of mitotic spindle organization,biological_process
80329,GO:0060237,"Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.",regulation of fungal-type cell wall organization,biological_process
80330,GO:0060241,"Binds to and stops, prevents or reduces the activity of lysozyme.",lysozyme inhibitor activity,molecular_function
80331,GO:0060242,"The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.",contact inhibition,biological_process
80332,GO:0060243,The negative regulation of cell growth in response to increased cell density.,negative regulation of cell growth involved in contact inhibition,biological_process
80333,GO:0060244,"Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.",negative regulation of cell proliferation involved in contact inhibition,biological_process
80334,GO:0060245,The series of events in which information about the density of cells in a population is received and converted into a molecular signal.,detection of cell density,biological_process
80335,GO:0060249,"A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",anatomical structure homeostasis,biological_process
80336,GO:0060250,A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.,germ-line stem-cell niche homeostasis,biological_process
80337,GO:0060251,"Any process that modulates the frequency, rate or extent of glial cell proliferation.",regulation of glial cell proliferation,biological_process
80338,GO:0060252,Any process that activates or increases the rate or extent of glial cell proliferation.,positive regulation of glial cell proliferation,biological_process
80339,GO:0060253,Any process that stops or decreases the rate or extent of glial cell proliferation.,negative regulation of glial cell proliferation,biological_process
80340,GO:0060254,Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.,regulation of N-terminal protein palmitoylation,biological_process
80341,GO:0060255,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.",regulation of macromolecule metabolic process,biological_process
80342,GO:0060256,"Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.",regulation of flocculation,biological_process
80343,GO:0060257,"Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.",negative regulation of flocculation,biological_process
80344,GO:0060258,"Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.",negative regulation of filamentous growth,biological_process
80345,GO:0060259,"Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.",regulation of feeding behavior,biological_process
80346,GO:0060260,"Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.",regulation of transcription initiation by RNA polymerase II,biological_process
80347,GO:0060261,"Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.",positive regulation of transcription initiation by RNA polymerase II,biological_process
80348,GO:0060262,Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.,negative regulation of N-terminal protein palmitoylation,biological_process
80349,GO:0060263,"Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",regulation of respiratory burst,biological_process
80350,GO:0060264,"Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",regulation of respiratory burst involved in inflammatory response,biological_process
80351,GO:0060265,"Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",positive regulation of respiratory burst involved in inflammatory response,biological_process
80352,GO:0060266,"Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",negative regulation of respiratory burst involved in inflammatory response,biological_process
80353,GO:0060267,"Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",positive regulation of respiratory burst,biological_process
80354,GO:0060268,"Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.",negative regulation of respiratory burst,biological_process
80355,GO:0060269,"The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.",centripetally migrating follicle cell migration,biological_process
80356,GO:0060270,The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.,main body follicle cell migration,biological_process
80357,GO:0060271,"The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.",cilium assembly,biological_process
80358,GO:0060272,The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.,embryonic skeletal joint morphogenesis,biological_process
80359,GO:0060273,"The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.",crying behavior,biological_process
80360,GO:0060278,"Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.",regulation of ovulation,biological_process
80361,GO:0060279,"Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.",positive regulation of ovulation,biological_process
80362,GO:0060280,"Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.",negative regulation of ovulation,biological_process
80363,GO:0060281,"Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",regulation of oocyte development,biological_process
80364,GO:0060282,"Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",positive regulation of oocyte development,biological_process
80365,GO:0060283,"Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.",negative regulation of oocyte development,biological_process
80366,GO:0060284,"Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",regulation of cell development,biological_process
80367,GO:0060285,"Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.",cilium-dependent cell motility,biological_process
80368,GO:0060287,"The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.",epithelial cilium movement involved in determination of left/right asymmetry,biological_process
80369,GO:0060288,Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.,formation of a compartment boundary,biological_process
80370,GO:0060289,A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.,compartment boundary maintenance,biological_process
80371,GO:0060290,The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.,transdifferentiation,biological_process
80372,GO:0060291,"A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.",long-term synaptic potentiation,biological_process
80373,GO:0060292,"A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.",long-term synaptic depression,biological_process
80374,GO:0060293,"Differentiated cytoplasm associated with an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.",germ plasm,cellular_component
80375,GO:0060294,Movement of cilia mediated by motor proteins that contributes to the movement of a cell.,cilium movement involved in cell motility,biological_process
80376,GO:0060295,Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.,regulation of cilium movement involved in cell motility,biological_process
80377,GO:0060296,Any process that modulates the frequency of cilium beating involved in ciliary motility.,regulation of cilium beat frequency involved in ciliary motility,biological_process
80378,GO:0060297,"Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.",regulation of sarcomere organization,biological_process
80379,GO:0060298,"Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.",positive regulation of sarcomere organization,biological_process
80380,GO:0060299,"Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.",negative regulation of sarcomere organization,biological_process
80381,GO:0060300,"Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.",regulation of cytokine activity,biological_process
80382,GO:0060302,"Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.",negative regulation of cytokine activity,biological_process
80383,GO:0060304,"Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.",regulation of phosphatidylinositol dephosphorylation,biological_process
80384,GO:0060305,"Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.",regulation of cell diameter,biological_process
80385,GO:0060306,"Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.",regulation of membrane repolarization,biological_process
80386,GO:0060307,Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.,regulation of ventricular cardiac muscle cell membrane repolarization,biological_process
80387,GO:0060308,"Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.",GTP cyclohydrolase I regulator activity,molecular_function
80388,GO:0060309,The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.,elastin catabolic process,biological_process
80389,GO:0060310,"Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.",regulation of elastin catabolic process,biological_process
80390,GO:0060311,"Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.",negative regulation of elastin catabolic process,biological_process
80391,GO:0060312,"Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.",regulation of blood vessel remodeling,biological_process
80392,GO:0060313,"Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.",negative regulation of blood vessel remodeling,biological_process
80393,GO:0060314,Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.,regulation of ryanodine-sensitive calcium-release channel activity,biological_process
80394,GO:0060315,Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.,negative regulation of ryanodine-sensitive calcium-release channel activity,biological_process
80395,GO:0060317,"A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",cardiac epithelial to mesenchymal transition,biological_process
80396,GO:0060318,Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.,definitive erythrocyte differentiation,biological_process
80397,GO:0060319,Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.,primitive erythrocyte differentiation,biological_process
80398,GO:0060320,"The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.",rejection of self pollen,biological_process
80399,GO:0060321,"The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.",acceptance of pollen,biological_process
80400,GO:0060322,The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.,head development,biological_process
80401,GO:0060323,The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.,head morphogenesis,biological_process
80402,GO:0060324,The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.,face development,biological_process
80403,GO:0060325,The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.,face morphogenesis,biological_process
80404,GO:0060326,The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,cell chemotaxis,biological_process
80405,GO:0060327,The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.,cytoplasmic actin-based contraction involved in cell motility,biological_process
80406,GO:0060328,The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.,cytoplasmic actin-based contraction involved in forward cell motility,biological_process
80407,GO:0060330,"Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.",regulation of response to type II interferon,biological_process
80408,GO:0060331,"Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.",negative regulation of response to type II interferon,biological_process
80409,GO:0060332,"Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.",positive regulation of response to type II interferon,biological_process
80410,GO:0060333,"The series of molecular signals initiated by interferon-gamma binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.",type II interferon-mediated signaling pathway,biological_process
80411,GO:0060334,"Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.",regulation of type II interferon-mediated signaling pathway,biological_process
80412,GO:0060335,"Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.",positive regulation of type II interferon-mediated signaling pathway,biological_process
80413,GO:0060336,"Any process that decreases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.",negative regulation of type II interferon-mediated signaling pathway,biological_process
80414,GO:0060337,"The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",type I interferon-mediated signaling pathway,biological_process
80415,GO:0060338,"Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway.",regulation of type I interferon-mediated signaling pathway,biological_process
80416,GO:0060339,"Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.",negative regulation of type I interferon-mediated signaling pathway,biological_process
80417,GO:0060340,"Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.",positive regulation of type I interferon-mediated signaling pathway,biological_process
80418,GO:0060341,"Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.",regulation of cellular localization,biological_process
80419,GO:0060342,"The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.",photoreceptor inner segment membrane,cellular_component
80420,GO:0060343,"The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.",trabecula formation,biological_process
80421,GO:0060344,"The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.",liver trabecula formation,biological_process
80422,GO:0060345,"The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.",spleen trabecula formation,biological_process
80423,GO:0060346,"The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.",bone trabecula formation,biological_process
80424,GO:0060347,"The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.",heart trabecula formation,biological_process
80425,GO:0060348,"The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.",bone development,biological_process
80426,GO:0060349,The process in which bones are generated and organized.,bone morphogenesis,biological_process
80427,GO:0060350,The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.,endochondral bone morphogenesis,biological_process
80428,GO:0060351,The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.,cartilage development involved in endochondral bone morphogenesis,biological_process
80429,GO:0060352,The appearance of a cell adhesion molecule due to biosynthesis or secretion.,cell adhesion molecule production,biological_process
80430,GO:0060353,"Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.",regulation of cell adhesion molecule production,biological_process
80431,GO:0060354,"Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.",negative regulation of cell adhesion molecule production,biological_process
80432,GO:0060355,"Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.",positive regulation of cell adhesion molecule production,biological_process
80433,GO:0060359,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.",response to ammonium ion,biological_process
80434,GO:0060360,"Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.",negative regulation of leucine import in response to ammonium ion,biological_process
80435,GO:0060361,"Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.",flight,biological_process
80436,GO:0060363,The process in which any suture between cranial bones is generated and organized.,cranial suture morphogenesis,biological_process
80437,GO:0060364,The process in which the frontal suture is generated and organized.,frontal suture morphogenesis,biological_process
80438,GO:0060365,The process in which the coronal suture is generated and organized.,coronal suture morphogenesis,biological_process
80439,GO:0060366,The process in which the lambdoid suture is generated and organized.,lambdoid suture morphogenesis,biological_process
80440,GO:0060367,The process in which the sagittal suture is generated and organized.,sagittal suture morphogenesis,biological_process
80441,GO:0060368,"Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway..",regulation of Fc receptor mediated stimulatory signaling pathway,biological_process
80442,GO:0060369,"Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.",positive regulation of Fc receptor mediated stimulatory signaling pathway,biological_process
80443,GO:0060370,The process of causing a cell to become susceptible to T cell mediated cytotoxicity.,susceptibility to T cell mediated cytotoxicity,biological_process
80444,GO:0060371,Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.,regulation of atrial cardiac muscle cell membrane depolarization,biological_process
80445,GO:0060372,Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.,regulation of atrial cardiac muscle cell membrane repolarization,biological_process
80446,GO:0060373,Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.,regulation of ventricular cardiac muscle cell membrane depolarization,biological_process
80447,GO:0060374,The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.,mast cell differentiation,biological_process
80448,GO:0060375,"Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.",regulation of mast cell differentiation,biological_process
80449,GO:0060376,"Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.",positive regulation of mast cell differentiation,biological_process
80450,GO:0060377,"Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.",negative regulation of mast cell differentiation,biological_process
80451,GO:0060378,Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.,regulation of brood size,biological_process
80452,GO:0060379,The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.,cardiac muscle cell myoblast differentiation,biological_process
80453,GO:0060382,"Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.",regulation of DNA strand elongation,biological_process
80454,GO:0060383,"Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.",positive regulation of DNA strand elongation,biological_process
80455,GO:0060384,The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.,innervation,biological_process
80456,GO:0060385,"The neurite development process that generates a long process of a neuron, as it invades a target tissue.",axonogenesis involved in innervation,biological_process
80457,GO:0060386,The assembly of a synapse within a target tissue in which a nerve is invading.,synapse assembly involved in innervation,biological_process
80458,GO:0060387,A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.,fertilization envelope,cellular_component
80459,GO:0060388,A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.,vitelline envelope,cellular_component
80460,GO:0060390,"Any process that modulates the rate, frequency or extent of SMAD protein signal transduction.",regulation of SMAD protein signal transduction,biological_process
80461,GO:0060391,"Any process that increases the rate, frequency or extent of SMAD protein signal transduction.",positive regulation of SMAD protein signal transduction,biological_process
80462,GO:0060392,"Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway.",negative regulation of SMAD protein signal transduction,biological_process
80463,GO:0060395,"An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.",SMAD protein signal transduction,biological_process
80464,GO:0060396,The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.,growth hormone receptor signaling pathway,biological_process
80465,GO:0060397,"The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.",growth hormone receptor signaling pathway via JAK-STAT,biological_process
80466,GO:0060398,"Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.",regulation of growth hormone receptor signaling pathway,biological_process
80467,GO:0060399,"Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.",positive regulation of growth hormone receptor signaling pathway,biological_process
80468,GO:0060400,"Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.",negative regulation of growth hormone receptor signaling pathway,biological_process
80469,GO:0060402,The directed movement of calcium ions (Ca2+) into the cytosol.,calcium ion transport into cytosol,biological_process
80470,GO:0060404,The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.,axonemal microtubule depolymerization,biological_process
80471,GO:0060405,"Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.",regulation of penile erection,biological_process
80472,GO:0060406,"Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.",positive regulation of penile erection,biological_process
80473,GO:0060407,"Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.",negative regulation of penile erection,biological_process
80474,GO:0060408,"Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.",regulation of acetylcholine metabolic process,biological_process
80475,GO:0060409,"Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.",positive regulation of acetylcholine metabolic process,biological_process
80476,GO:0060411,The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.,cardiac septum morphogenesis,biological_process
80477,GO:0060412,The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.,ventricular septum morphogenesis,biological_process
80478,GO:0060413,The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.,atrial septum morphogenesis,biological_process
80479,GO:0060414,The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.,aorta smooth muscle tissue morphogenesis,biological_process
80480,GO:0060415,The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.,muscle tissue morphogenesis,biological_process
80481,GO:0060416,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.",response to growth hormone,biological_process
80482,GO:0060417,The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.,yolk,cellular_component
80483,GO:0060418,"Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.",yolk plasma,cellular_component
80484,GO:0060419,The increase in size or mass of the heart.,heart growth,biological_process
80485,GO:0060420,Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.,regulation of heart growth,biological_process
80486,GO:0060421,Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.,positive regulation of heart growth,biological_process
80487,GO:0060422,"Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.",peptidyl-dipeptidase inhibitor activity,molecular_function
80488,GO:0060423,The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.,foregut regionalization,biological_process
80489,GO:0060424,The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.,lung field specification,biological_process
80490,GO:0060425,The process in which the anatomical structures of the lung are generated and organized.,lung morphogenesis,biological_process
80491,GO:0060426,The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.,lung vasculature development,biological_process
80492,GO:0060427,The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.,lung connective tissue development,biological_process
80493,GO:0060428,The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.,lung epithelium development,biological_process
80494,GO:0060429,"The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.",epithelium development,biological_process
80495,GO:0060430,The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.,lung saccule development,biological_process
80496,GO:0060431,The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.,primary lung bud formation,biological_process
80497,GO:0060432,"Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.",lung pattern specification process,biological_process
80498,GO:0060433,The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.,bronchus development,biological_process
80499,GO:0060434,The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.,bronchus morphogenesis,biological_process
80500,GO:0060435,The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.,bronchiole development,biological_process
80501,GO:0060436,The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.,bronchiole morphogenesis,biological_process
80502,GO:0060437,"The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into t...",lung growth,biological_process
80503,GO:0060438,"The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.",trachea development,biological_process
80504,GO:0060439,The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.,trachea morphogenesis,biological_process
80505,GO:0060440,The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.,trachea formation,biological_process
80506,GO:0060441,"The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.",epithelial tube branching involved in lung morphogenesis,biological_process
80507,GO:0060442,The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.,branching involved in prostate gland morphogenesis,biological_process
80508,GO:0060443,The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.,mammary gland morphogenesis,biological_process
80509,GO:0060444,The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.,branching involved in mammary gland duct morphogenesis,biological_process
80510,GO:0060445,The process in which the branching structure of the salivary gland is generated and organized.,branching involved in salivary gland morphogenesis,biological_process
80511,GO:0060446,The process in which the anatomical structures of branches in the open tracheal system are generated and organized.,branching involved in open tracheal system development,biological_process
80512,GO:0060447,The process in which a region of the lung epithelium initiates an outgrowth.,bud outgrowth involved in lung branching,biological_process
80513,GO:0060448,The process in which a lung bud bifurcates.,dichotomous subdivision of terminal units involved in lung branching,biological_process
80514,GO:0060449,The process in which a bud in the lung grows out from the point where it is formed.,bud elongation involved in lung branching,biological_process
80515,GO:0060450,"Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.",positive regulation of hindgut contraction,biological_process
80516,GO:0060451,"Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.",negative regulation of hindgut contraction,biological_process
80517,GO:0060452,"Any process that increases the frequency, rate or extent of cardiac muscle contraction.",positive regulation of cardiac muscle contraction,biological_process
80518,GO:0060453,Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.,regulation of gastric acid secretion,biological_process
80519,GO:0060454,Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.,positive regulation of gastric acid secretion,biological_process
80520,GO:0060455,Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.,negative regulation of gastric acid secretion,biological_process
80521,GO:0060456,"Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",positive regulation of digestive system process,biological_process
80522,GO:0060457,"Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.",negative regulation of digestive system process,biological_process
80523,GO:0060458,The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.,right lung development,biological_process
80524,GO:0060459,The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.,left lung development,biological_process
80525,GO:0060460,The process in which anatomical structures of the left lung are generated and organized.,left lung morphogenesis,biological_process
80526,GO:0060461,The process in which anatomical structures of the right lung are generated and organized.,right lung morphogenesis,biological_process
80527,GO:0060462,The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.,lung lobe development,biological_process
80528,GO:0060463,The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.,lung lobe morphogenesis,biological_process
80529,GO:0060464,The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.,lung lobe formation,biological_process
80530,GO:0060465,The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.,pharynx development,biological_process
80531,GO:0060466,Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.,activation of meiosis involved in egg activation,biological_process
80532,GO:0060467,"Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).",negative regulation of fertilization,biological_process
80533,GO:0060468,"The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.",prevention of polyspermy,biological_process
80534,GO:0060470,The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.,positive regulation of cytosolic calcium ion concentration involved in egg activation,biological_process
80535,GO:0060471,The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.,cortical granule exocytosis,biological_process
80536,GO:0060472,"Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.",positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration,biological_process
80537,GO:0060473,A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.,cortical granule,cellular_component
80538,GO:0060474,The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.,positive regulation of flagellated sperm motility involved in capacitation,biological_process
80539,GO:0060476,"The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.",protein localization involved in acrosome reaction,biological_process
80540,GO:0060478,The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.,acrosomal vesicle exocytosis,biological_process
80541,GO:0060479,"The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.",lung cell differentiation,biological_process
80542,GO:0060480,The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.,lung goblet cell differentiation,biological_process
80543,GO:0060481,The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.,lobar bronchus epithelium development,biological_process
80544,GO:0060482,The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.,lobar bronchus development,biological_process
80545,GO:0060483,The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.,lobar bronchus mesenchyme development,biological_process
80546,GO:0060484,The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.,lung-associated mesenchyme development,biological_process
80547,GO:0060485,"The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.",mesenchyme development,biological_process
80548,GO:0060486,The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.,club cell differentiation,biological_process
80549,GO:0060487,The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.,lung epithelial cell differentiation,biological_process
80550,GO:0060488,The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.,orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis,biological_process
80551,GO:0060489,The process in which a lung bud bifurcates parallel to the plane of the previous bud.,planar dichotomous subdivision of terminal units involved in lung branching morphogenesis,biological_process
80552,GO:0060490,The process in which a branch forms along the side of the lung epithelial tube.,lateral sprouting involved in lung morphogenesis,biological_process
80553,GO:0060491,"Any process that modulates the rate, frequency, or extent of cell projection assembly.",regulation of cell projection assembly,biological_process
80554,GO:0060492,The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.,lung induction,biological_process
80555,GO:0060494,Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.,inductive mesenchymal-endodermal cell signaling,biological_process
80556,GO:0060496,Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.,mesenchymal-epithelial cell signaling involved in lung development,biological_process
80557,GO:0060497,Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.,mesenchymal-endodermal cell signaling,biological_process
80558,GO:0060501,Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.,positive regulation of epithelial cell proliferation involved in lung morphogenesis,biological_process
80559,GO:0060502,"The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.",epithelial cell proliferation involved in lung morphogenesis,biological_process
80560,GO:0060503,The process in which a bud in the lung increases radially.,bud dilation involved in lung branching,biological_process
80561,GO:0060506,The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.,smoothened signaling pathway involved in lung development,biological_process
80562,GO:0060508,"The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.",lung basal cell differentiation,biological_process
80563,GO:0060509,The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.,type I pneumocyte differentiation,biological_process
80564,GO:0060510,The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.,type II pneumocyte differentiation,biological_process
80565,GO:0060512,The process in which the anatomical structures of a prostate gland are generated and organized.,prostate gland morphogenesis,biological_process
80566,GO:0060513,"The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.",prostatic bud formation,biological_process
80567,GO:0060514,The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.,prostate induction,biological_process
80568,GO:0060515,The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.,prostate field specification,biological_process
80569,GO:0060516,The increase in size of the prostatic bud as it forms.,primary prostatic bud elongation,biological_process
80570,GO:0060517,"The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.",epithelial cell proliferation involved in prostatic bud elongation,biological_process
80571,GO:0060522,Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.,inductive mesenchymal to epithelial cell signaling,biological_process
80572,GO:0060523,The developmental growth process in which solid chords of prostate epithelium increase in length.,prostate epithelial cord elongation,biological_process
80573,GO:0060524,The process in which a prostate epithelial cord bifurcates at its end.,dichotomous subdivision of prostate epithelial cord terminal unit,biological_process
80574,GO:0060525,"The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.",prostate glandular acinus development,biological_process
80575,GO:0060526,The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.,prostate glandular acinus morphogenesis,biological_process
80576,GO:0060527,The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.,prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis,biological_process
80577,GO:0060528,The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.,secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development,biological_process
80578,GO:0060529,The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.,squamous basal epithelial stem cell differentiation involved in prostate gland acinus development,biological_process
80579,GO:0060532,"The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",bronchus cartilage development,biological_process
80580,GO:0060533,The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.,bronchus cartilage morphogenesis,biological_process
80581,GO:0060534,"The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",trachea cartilage development,biological_process
80582,GO:0060535,The process in which the anatomical structures of cartilage in the trachea are generated and organized.,trachea cartilage morphogenesis,biological_process
80583,GO:0060536,The process in which the anatomical structures of cartilage are generated and organized.,cartilage morphogenesis,biological_process
80584,GO:0060537,"The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.",muscle tissue development,biological_process
80585,GO:0060538,The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.,skeletal muscle organ development,biological_process
80586,GO:0060539,The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.,diaphragm development,biological_process
80587,GO:0060540,The process in which the anatomical structures of the diaphragm are generated and organized.,diaphragm morphogenesis,biological_process
80588,GO:0060541,The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.,respiratory system development,biological_process
80589,GO:0060542,"Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.",regulation of strand invasion,biological_process
80590,GO:0060543,"Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.",negative regulation of strand invasion,biological_process
80591,GO:0060544,"Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.",regulation of necroptotic process,biological_process
80592,GO:0060545,"Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.",positive regulation of necroptotic process,biological_process
80593,GO:0060546,"Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.",negative regulation of necroptotic process,biological_process
80594,GO:0060552,"Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.","positive regulation of fructose 1,6-bisphosphate metabolic process",biological_process
80595,GO:0060556,"Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",regulation of vitamin D biosynthetic process,biological_process
80596,GO:0060557,"Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).",positive regulation of vitamin D biosynthetic process,biological_process
80597,GO:0060560,The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.,developmental growth involved in morphogenesis,biological_process
80598,GO:0060561,Any apoptotic process that contributes to the shaping of an anatomical structure.,apoptotic process involved in morphogenesis,biological_process
80599,GO:0060562,"The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.",epithelial tube morphogenesis,biological_process
80600,GO:0060563,The process in which epiblast cells acquire specialized features of neuroepithelial cells.,neuroepithelial cell differentiation,biological_process
80601,GO:0060566,"Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.",positive regulation of termination of DNA-templated transcription,biological_process
80602,GO:0060567,"Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.",negative regulation of termination of DNA-templated transcription,biological_process
80603,GO:0060568,"Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.",regulation of peptide hormone processing,biological_process
80604,GO:0060569,"Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.",positive regulation of peptide hormone processing,biological_process
80605,GO:0060570,"Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.",negative regulation of peptide hormone processing,biological_process
80606,GO:0060571,The morphogenetic process in which an epithelial sheet bends along a linear axis.,morphogenesis of an epithelial fold,biological_process
80607,GO:0060572,The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.,morphogenesis of an epithelial bud,biological_process
80608,GO:0060573,"The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.",cell fate specification involved in pattern specification,biological_process
80609,GO:0060574,"The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.",intestinal epithelial cell maturation,biological_process
80610,GO:0060575,The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.,intestinal epithelial cell differentiation,biological_process
80611,GO:0060576,"The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.",intestinal epithelial cell development,biological_process
80612,GO:0060577,The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.,pulmonary vein morphogenesis,biological_process
80613,GO:0060578,The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.,superior vena cava morphogenesis,biological_process
80614,GO:0060579,The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.,ventral spinal cord interneuron fate commitment,biological_process
80615,GO:0060580,"The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.",ventral spinal cord interneuron fate determination,biological_process
80616,GO:0060581,The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.,cell fate commitment involved in pattern specification,biological_process
80617,GO:0060582,"A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.",cell fate determination involved in pattern specification,biological_process
80618,GO:0060583,Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.,regulation of actin cortical patch localization,biological_process
80619,GO:0060586,"A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.",multicellular organismal-level iron ion homeostasis,biological_process
80620,GO:0060587,"Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.",regulation of lipoprotein lipid oxidation,biological_process
80621,GO:0060588,"Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.",negative regulation of lipoprotein lipid oxidation,biological_process
80622,GO:0060589,Binds to and modulates the activity of an NTPase.,nucleoside-triphosphatase regulator activity,molecular_function
80623,GO:0060590,Binds to and modulates the activity of an ATP hydrolysis activity.,ATPase regulator activity,molecular_function
80624,GO:0060591,"The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.",chondroblast differentiation,biological_process
80625,GO:0060592,The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.,mammary gland formation,biological_process
80626,GO:0060594,The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.,mammary gland specification,biological_process
80627,GO:0060595,The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.,fibroblast growth factor receptor signaling pathway involved in mammary gland specification,biological_process
80628,GO:0060596,The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.,mammary placode formation,biological_process
80629,GO:0060598,The process in which the terminal end of a mammary duct bifurcates.,dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis,biological_process
80630,GO:0060599,The process in which a branch forms along the side of a mammary duct.,lateral sprouting involved in mammary gland duct morphogenesis,biological_process
80631,GO:0060600,"The process in which an epithelial cord, rod or tube bifurcates at its end.",dichotomous subdivision of an epithelial terminal unit,biological_process
80632,GO:0060601,The process in which a branch forms along the side of an epithelium.,lateral sprouting from an epithelium,biological_process
80633,GO:0060602,The growth process in which a branch increases in length from its base to its tip.,branch elongation of an epithelium,biological_process
80634,GO:0060603,The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.,mammary gland duct morphogenesis,biological_process
80635,GO:0060604,Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.,mammary gland duct cavitation,biological_process
80636,GO:0060605,The formation of a lumen by hollowing out a solid rod or cord.,tube lumen cavitation,biological_process
80637,GO:0060606,Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.,tube closure,biological_process
80638,GO:0060611,"The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.",mammary gland fat development,biological_process
80639,GO:0060612,"The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.",adipose tissue development,biological_process
80640,GO:0060613,The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.,fat pad development,biological_process
80641,GO:0060615,The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.,mammary gland bud formation,biological_process
80642,GO:0060616,The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.,mammary gland cord formation,biological_process
80643,GO:0060617,Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.,positive regulation of mammary placode formation by mesenchymal-epithelial signaling,biological_process
80644,GO:0060618,"The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.",nipple development,biological_process
80645,GO:0060620,"Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.",regulation of cholesterol import,biological_process
80646,GO:0060621,"Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.",negative regulation of cholesterol import,biological_process
80647,GO:0060622,"Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.",regulation of ascospore wall beta-glucan biosynthetic process,biological_process
80648,GO:0060623,"Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.",regulation of chromosome condensation,biological_process
80649,GO:0060624,"Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.",regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process,biological_process
80650,GO:0060625,"Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.",regulation of protein deneddylation,biological_process
80651,GO:0060627,"Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.",regulation of vesicle-mediated transport,biological_process
80652,GO:0060628,"Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.",regulation of ER to Golgi vesicle-mediated transport,biological_process
80653,GO:0060629,"Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homol...",regulation of homologous chromosome segregation,biological_process
80654,GO:0060631,"Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.",regulation of meiosis I,biological_process
80655,GO:0060632,"Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.",regulation of microtubule-based movement,biological_process
80656,GO:0060633,"Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.",negative regulation of transcription initiation by RNA polymerase II,biological_process
80657,GO:0060634,"Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.","regulation of 4,6-pyruvylated galactose residue biosynthetic process",biological_process
80658,GO:0060635,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.",positive regulation of (1->3)-beta-D-glucan biosynthetic process,biological_process
80659,GO:0060636,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.",negative regulation of (1->3)-beta-D-glucan biosynthetic process,biological_process
80660,GO:0060637,"The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.",positive regulation of lactation by mesenchymal-epithelial cell signaling,biological_process
80661,GO:0060638,Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.,mesenchymal-epithelial cell signaling,biological_process
80662,GO:0060639,Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.,positive regulation of salivary gland formation by mesenchymal-epithelial signaling,biological_process
80663,GO:0060640,Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.,positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling,biological_process
80664,GO:0060641,The process in which the epithelium of the mammary duct is destroyed in males.,mammary gland duct regression in males,biological_process
80665,GO:0060644,The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.,mammary gland epithelial cell differentiation,biological_process
80666,GO:0060645,The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.,peripheral mammary gland bud epithelial cell differentiation,biological_process
80667,GO:0060646,The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.,internal mammary gland bud epithelial cell differentiation,biological_process
80668,GO:0060648,"The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.",mammary gland bud morphogenesis,biological_process
80669,GO:0060649,The process in which the mammary gland bud grows along its axis.,mammary gland bud elongation,biological_process
80670,GO:0060652,The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.,mammary gland cord morphogenesis,biological_process
80671,GO:0060654,The process in which the mammary gland sprout grows along its axis.,mammary gland cord elongation,biological_process
80672,GO:0060657,"Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.",regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling,biological_process
80673,GO:0060658,The process in which the nipple is generated and organized.,nipple morphogenesis,biological_process
80674,GO:0060659,The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.,nipple sheath formation,biological_process
80675,GO:0060661,The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.,submandibular salivary gland formation,biological_process
80676,GO:0060662,The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.,salivary gland cavitation,biological_process
80677,GO:0060664,"The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.",epithelial cell proliferation involved in salivary gland morphogenesis,biological_process
80678,GO:0060665,"Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.",regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling,biological_process
80679,GO:0060666,The process in which a salivary epithelial cord bifurcates at its end.,dichotomous subdivision of terminal units involved in salivary gland branching,biological_process
80680,GO:0060667,"The differential growth of the salivary branches along their axis, resulting in the growth of a branch.",branch elongation involved in salivary gland morphogenesis,biological_process
80681,GO:0060668,"Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.",regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling,biological_process
80682,GO:0060669,The process in which the embryonic placenta is generated and organized.,embryonic placenta morphogenesis,biological_process
80683,GO:0060670,The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.,branching involved in labyrinthine layer morphogenesis,biological_process
80684,GO:0060671,The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.,epithelial cell differentiation involved in embryonic placenta development,biological_process
80685,GO:0060672,The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.,epithelial cell morphogenesis involved in placental branching,biological_process
80686,GO:0060674,"The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.",placenta blood vessel development,biological_process
80687,GO:0060675,The process in which the ureteric bud is generated and organized.,ureteric bud morphogenesis,biological_process
80688,GO:0060676,The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.,ureteric bud formation,biological_process
80689,GO:0060677,The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.,ureteric bud elongation,biological_process
80690,GO:0060678,The process in which a ureteric bud bifurcates at its end.,dichotomous subdivision of terminal units involved in ureteric bud branching,biological_process
80691,GO:0060681,The growth of a branch of the ureteric bud along its axis.,branch elongation involved in ureteric bud branching,biological_process
80692,GO:0060682,The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.,primary ureteric bud growth,biological_process
80693,GO:0060683,"Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.",regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling,biological_process
80694,GO:0060684,Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.,epithelial-mesenchymal cell signaling,biological_process
80695,GO:0060685,"Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.",regulation of prostatic bud formation,biological_process
80696,GO:0060686,"Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.",negative regulation of prostatic bud formation,biological_process
80697,GO:0060687,"Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.",regulation of branching involved in prostate gland morphogenesis,biological_process
80698,GO:0060688,"Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.",regulation of morphogenesis of a branching structure,biological_process
80699,GO:0060689,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.,cell differentiation involved in salivary gland development,biological_process
80700,GO:0060690,The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.,epithelial cell differentiation involved in salivary gland development,biological_process
80701,GO:0060691,"The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.",epithelial cell maturation involved in salivary gland development,biological_process
80702,GO:0060693,"Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.",regulation of branching involved in salivary gland morphogenesis,biological_process
80703,GO:0060696,"Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.",regulation of phospholipid catabolic process,biological_process
80704,GO:0060697,"Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.",positive regulation of phospholipid catabolic process,biological_process
80705,GO:0060698,"Binds to and stops, prevents or reduces the activity of endoribonuclease.",endoribonuclease inhibitor activity,molecular_function
80706,GO:0060699,"Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.",regulation of endoribonuclease activity,biological_process
80707,GO:0060700,"Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.",regulation of ribonuclease activity,biological_process
80708,GO:0060702,"Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.",negative regulation of endoribonuclease activity,biological_process
80709,GO:0060703,"Binds to and stops, prevents or reduces the activity of deoxyribonuclease.",deoxyribonuclease inhibitor activity,molecular_function
80710,GO:0060706,The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.,cell differentiation involved in embryonic placenta development,biological_process
80711,GO:0060707,The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.,trophoblast giant cell differentiation,biological_process
80712,GO:0060708,The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.,spongiotrophoblast differentiation,biological_process
80713,GO:0060709,The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.,glycogen cell differentiation involved in embryonic placenta development,biological_process
80714,GO:0060710,The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.,chorio-allantoic fusion,biological_process
80715,GO:0060711,"The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.",labyrinthine layer development,biological_process
80716,GO:0060712,The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.,spongiotrophoblast layer development,biological_process
80717,GO:0060713,The process in which the labyrinthine layer of the placenta is generated and organized.,labyrinthine layer morphogenesis,biological_process
80718,GO:0060714,The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.,labyrinthine layer formation,biological_process
80719,GO:0060715,The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.,syncytiotrophoblast cell differentiation involved in labyrinthine layer development,biological_process
80720,GO:0060716,"The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.",labyrinthine layer blood vessel development,biological_process
80721,GO:0060717,The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.,chorion development,biological_process
80722,GO:0060718,The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.,chorionic trophoblast cell differentiation,biological_process
80723,GO:0060719,"The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.",chorionic trophoblast cell development,biological_process
80724,GO:0060720,"The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.",spongiotrophoblast cell proliferation,biological_process
80725,GO:0060721,"Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.",regulation of spongiotrophoblast cell proliferation,biological_process
80726,GO:0060722,"The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.",cell proliferation involved in embryonic placenta development,biological_process
80727,GO:0060723,"Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.",regulation of cell proliferation involved in embryonic placenta development,biological_process
80728,GO:0060729,A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.,intestinal epithelial structure maintenance,biological_process
80729,GO:0060730,"Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.",regulation of intestinal epithelial structure maintenance,biological_process
80730,GO:0060731,"Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.",positive regulation of intestinal epithelial structure maintenance,biological_process
80731,GO:0060732,"Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",positive regulation of inositol phosphate biosynthetic process,biological_process
80732,GO:0060734,"Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.",regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation,biological_process
80733,GO:0060735,"Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.",regulation of eIF2 alpha phosphorylation by dsRNA,biological_process
80734,GO:0060736,"The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.",prostate gland growth,biological_process
80735,GO:0060737,The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.,prostate gland morphogenetic growth,biological_process
80736,GO:0060738,Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.,epithelial-mesenchymal signaling involved in prostate gland development,biological_process
80737,GO:0060739,Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.,mesenchymal-epithelial cell signaling involved in prostate gland development,biological_process
80738,GO:0060740,"The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.",prostate gland epithelium morphogenesis,biological_process
80739,GO:0060741,The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.,prostate gland stromal morphogenesis,biological_process
80740,GO:0060742,The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.,epithelial cell differentiation involved in prostate gland development,biological_process
80741,GO:0060743,"The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.",epithelial cell maturation involved in prostate gland development,biological_process
80742,GO:0060744,The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.,mammary gland branching involved in thelarche,biological_process
80743,GO:0060745,The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.,mammary gland branching involved in pregnancy,biological_process
80744,GO:0060746,A reproductive behavior in which a parent cares for and rears offspring.,parental behavior,biological_process
80745,GO:0060747,A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.,oral incubation,biological_process
80746,GO:0060748,The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.,tertiary branching involved in mammary gland duct morphogenesis,biological_process
80747,GO:0060749,"The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.",mammary gland alveolus development,biological_process
80748,GO:0060750,"The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.",epithelial cell proliferation involved in mammary gland duct elongation,biological_process
80749,GO:0060751,The developmental growth process in which a branch of a mammary gland duct elongates.,branch elongation involved in mammary gland duct branching,biological_process
80750,GO:0060752,A process in which phytosterols are taken up from the contents of the intestine.,intestinal phytosterol absorption,biological_process
80751,GO:0060753,"Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.",regulation of mast cell chemotaxis,biological_process
80752,GO:0060754,"Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.",positive regulation of mast cell chemotaxis,biological_process
80753,GO:0060755,"Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.",negative regulation of mast cell chemotaxis,biological_process
80754,GO:0060756,Behavior by which an organism locates food.,foraging behavior,biological_process
80755,GO:0060757,Behavior by which an adult locates food.,adult foraging behavior,biological_process
80756,GO:0060758,Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.,foraging behavior by probing substrate,biological_process
80757,GO:0060759,"Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.",regulation of response to cytokine stimulus,biological_process
80758,GO:0060760,"Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.",positive regulation of response to cytokine stimulus,biological_process
80759,GO:0060761,"Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.",negative regulation of response to cytokine stimulus,biological_process
80760,GO:0060762,"Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.",regulation of branching involved in mammary gland duct morphogenesis,biological_process
80761,GO:0060763,"The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.",mammary duct terminal end bud growth,biological_process
80762,GO:0060764,"Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.",cell-cell signaling involved in mammary gland development,biological_process
80763,GO:0060765,"Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.",regulation of androgen receptor signaling pathway,biological_process
80764,GO:0060766,"Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.",negative regulation of androgen receptor signaling pathway,biological_process
80765,GO:0060767,"The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.",epithelial cell proliferation involved in prostate gland development,biological_process
80766,GO:0060768,"Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.",regulation of epithelial cell proliferation involved in prostate gland development,biological_process
80767,GO:0060769,"Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.",positive regulation of epithelial cell proliferation involved in prostate gland development,biological_process
80768,GO:0060770,"Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.",negative regulation of epithelial cell proliferation involved in prostate gland development,biological_process
80769,GO:0060771,The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.,phyllotactic patterning,biological_process
80770,GO:0060772,The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.,leaf phyllotactic patterning,biological_process
80771,GO:0060773,The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.,flower phyllotactic patterning,biological_process
80772,GO:0060776,The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.,simple leaf morphogenesis,biological_process
80773,GO:0060777,The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.,compound leaf morphogenesis,biological_process
80774,GO:0060778,The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.,primary leaflet morphogenesis,biological_process
80775,GO:0060779,The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.,secondary leaflet morphogenesis,biological_process
80776,GO:0060780,The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.,intercalary leaflet morphogenesis,biological_process
80777,GO:0060783,The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.,mesenchymal smoothened signaling pathway involved in prostate gland development,biological_process
80778,GO:0060784,"Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.",regulation of cell proliferation involved in tissue homeostasis,biological_process
80779,GO:0060785,Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.,regulation of apoptosis involved in tissue homeostasis,biological_process
80780,GO:0060786,"Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.",regulation of cell differentiation involved in tissue homeostasis,biological_process
80781,GO:0060787,"Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.",positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway,biological_process
80782,GO:0060788,The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.,ectodermal placode formation,biological_process
80783,GO:0060789,The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.,hair follicle placode formation,biological_process
80784,GO:0060790,The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.,tooth placode formation,biological_process
80785,GO:0060791,The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.,sebaceous gland placode formation,biological_process
80786,GO:0060792,"The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.",sweat gland development,biological_process
80787,GO:0060793,The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.,sweat gland placode formation,biological_process
80788,GO:0060794,The process in which the anatomical structures of the leaflet are generated and organized.,leaflet morphogenesis,biological_process
80789,GO:0060795,"The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.",cell fate commitment involved in formation of primary germ layer,biological_process
80790,GO:0060800,"Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.",regulation of cell differentiation involved in embryonic placenta development,biological_process
80791,GO:0060802,Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell.,epiblast cell-extraembryonic ectoderm cell signaling,biological_process
80792,GO:0060806,"Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.",negative regulation of cell differentiation involved in embryonic placenta development,biological_process
80793,GO:0060809,"The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.",mesodermal to mesenchymal transition involved in gastrulation,biological_process
80794,GO:0060810,"Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.",intracellular mRNA localization involved in pattern specification process,biological_process
80795,GO:0060811,"Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.",intracellular mRNA localization involved in anterior/posterior axis specification,biological_process
80796,GO:0060812,Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.,orthodenticle mRNA localization,biological_process
80797,GO:0060813,"Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.",anterior mRNA localization involved in anterior/posterior axis specification,biological_process
80798,GO:0060814,Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.,posterior mRNA localization involved in anterior/posterior axis specification,biological_process
80799,GO:0060816,"Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.",random inactivation of X chromosome,biological_process
80800,GO:0060818,"Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting.",inactivation of paternal X chromosome by genomic imprinting,biological_process
80801,GO:0060828,"Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.",regulation of canonical Wnt signaling pathway,biological_process
80802,GO:0060831,The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.,smoothened signaling pathway involved in dorsal/ventral neural tube patterning,biological_process
80803,GO:0060832,"The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.",oocyte animal/vegetal axis specification,biological_process
80804,GO:0060834,"The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.",oral/aboral axis specification,biological_process
80805,GO:0060836,"The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.",lymphatic endothelial cell differentiation,biological_process
80806,GO:0060837,"The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.",blood vessel endothelial cell differentiation,biological_process
80807,GO:0060838,The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.,lymphatic endothelial cell fate commitment,biological_process
80808,GO:0060839,The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.,endothelial cell fate commitment,biological_process
80809,GO:0060840,"The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.",artery development,biological_process
80810,GO:0060841,The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.,venous blood vessel development,biological_process
80811,GO:0060842,"The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.",arterial endothelial cell differentiation,biological_process
80812,GO:0060843,"The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.",venous endothelial cell differentiation,biological_process
80813,GO:0060844,The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.,arterial endothelial cell fate commitment,biological_process
80814,GO:0060845,The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.,venous endothelial cell fate commitment,biological_process
80815,GO:0060846,The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.,blood vessel endothelial cell fate commitment,biological_process
80816,GO:0060847,"The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.",endothelial cell fate specification,biological_process
80817,GO:0060848,"A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.",endothelial cell fate determination,biological_process
80818,GO:0060853,The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.,Notch signaling pathway involved in arterial endothelial cell fate commitment,biological_process
80819,GO:0060854,The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.,branching involved in lymph vessel morphogenesis,biological_process
80820,GO:0060855,The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.,venous endothelial cell migration involved in lymph vessel development,biological_process
80821,GO:0060856,Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.,establishment of blood-brain barrier,biological_process
80822,GO:0060857,Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.,establishment of glial blood-brain barrier,biological_process
80823,GO:0060860,"Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.",regulation of floral organ abscission,biological_process
80824,GO:0060861,"Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.",positive regulation of floral organ abscission,biological_process
80825,GO:0060862,"Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.",negative regulation of floral organ abscission,biological_process
80826,GO:0060863,"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.",regulation of floral organ abscission by signal transduction,biological_process
80827,GO:0060866,The controlled shedding of a leaf.,leaf abscission,biological_process
80828,GO:0060867,The controlled shedding of a fruit.,fruit abscission,biological_process
80829,GO:0060872,The progression of the semicircular canal from its initial formation to the mature structure.,semicircular canal development,biological_process
80830,GO:0060873,The progession of the anterior semicircular canal from its initial formation to the mature structure.,anterior semicircular canal development,biological_process
80831,GO:0060874,The progession of the posterior semicircular canal from its initial formation to the mature structure.,posterior semicircular canal development,biological_process
80832,GO:0060875,The progession of the lateral semicircular canal from its initial formation to the mature structure.,lateral semicircular canal development,biological_process
80833,GO:0060876,The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.,semicircular canal formation,biological_process
80834,GO:0060879,Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.,semicircular canal fusion,biological_process
80835,GO:0060884,The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.,clearance of cells from fusion plate,biological_process
80836,GO:0060885,"Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.",clearance of cells from fusion plate by apoptotic process,biological_process
80837,GO:0060886,"The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.",clearance of cells from fusion plate by epithelial to mesenchymal transition,biological_process
80838,GO:0060887,"The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.",limb epidermis development,biological_process
80839,GO:0060888,"The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.",limb epidermis stratification,biological_process
80840,GO:0060889,The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.,limb basal epidermal cell differentiation,biological_process
80841,GO:0060890,The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.,limb spinous cell differentiation,biological_process
80842,GO:0060891,The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.,limb granular cell differentiation,biological_process
80843,GO:0060892,"The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",limb basal epidermal cell fate specification,biological_process
80844,GO:0060893,"The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",limb granular cell fate specification,biological_process
80845,GO:0060894,"The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",limb spinous cell fate specification,biological_process
80846,GO:0060896,The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.,neural plate pattern specification,biological_process
80847,GO:0060897,The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.,neural plate regionalization,biological_process
80848,GO:0060898,The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.,eye field cell fate commitment involved in camera-type eye formation,biological_process
80849,GO:0060900,The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.,embryonic camera-type eye formation,biological_process
80850,GO:0060903,"Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.",positive regulation of meiosis I,biological_process
80851,GO:0060904,"Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).",regulation of protein folding in endoplasmic reticulum,biological_process
80852,GO:0060905,"Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.",regulation of induction of conjugation upon nitrogen starvation,biological_process
80853,GO:0060906,"Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation.",negative regulation of regulatory ncRNA-mediated heterochromatin formation,biological_process
80854,GO:0060907,"Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",positive regulation of macrophage cytokine production,biological_process
80855,GO:0060908,The maintenance of the number of copies of extrachromosomal plasmid DNA.,plasmid copy number maintenance,biological_process
80856,GO:0060911,The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.,cardiac cell fate commitment,biological_process
80857,GO:0060912,"The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.",cardiac cell fate specification,biological_process
80858,GO:0060913,"The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.",cardiac cell fate determination,biological_process
80859,GO:0060914,The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.,heart formation,biological_process
80860,GO:0060915,The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.,mesenchymal cell differentiation involved in lung development,biological_process
80861,GO:0060916,"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.",mesenchymal cell proliferation involved in lung development,biological_process
80862,GO:0060917,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.",regulation of (1->6)-beta-D-glucan biosynthetic process,biological_process
80863,GO:0060918,"The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth.",auxin transport,biological_process
80864,GO:0060919,The directed movement of auxins from outside of a cell into a cell.,auxin import into cell,biological_process
80865,GO:0060920,The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.,cardiac pacemaker cell differentiation,biological_process
80866,GO:0060921,The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.,sinoatrial node cell differentiation,biological_process
80867,GO:0060922,The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.,atrioventricular node cell differentiation,biological_process
80868,GO:0060923,The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.,cardiac muscle cell fate commitment,biological_process
80869,GO:0060924,The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.,atrial cardiac muscle cell fate commitment,biological_process
80870,GO:0060925,The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.,ventricular cardiac muscle cell fate commitment,biological_process
80871,GO:0060926,"The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.",cardiac pacemaker cell development,biological_process
80872,GO:0060927,The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.,cardiac pacemaker cell fate commitment,biological_process
80873,GO:0060928,"The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.",atrioventricular node cell development,biological_process
80874,GO:0060929,The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.,atrioventricular node cell fate commitment,biological_process
80875,GO:0060930,The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.,sinoatrial node cell fate commitment,biological_process
80876,GO:0060931,"The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.",sinoatrial node cell development,biological_process
80877,GO:0060932,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.,His-Purkinje system cell differentiation,biological_process
80878,GO:0060933,"The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.",His-Purkinje system cell development,biological_process
80879,GO:0060934,The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.,His-Purkinje system cell fate commitment,biological_process
80880,GO:0060935,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,cardiac fibroblast cell differentiation,biological_process
80881,GO:0060936,"The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.",cardiac fibroblast cell development,biological_process
80882,GO:0060937,The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,cardiac fibroblast cell fate commitment,biological_process
80883,GO:0060938,The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,epicardium-derived cardiac fibroblast cell differentiation,biological_process
80884,GO:0060939,"The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.",epicardium-derived cardiac fibroblast cell development,biological_process
80885,GO:0060940,"A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.",epithelial to mesenchymal transition involved in cardiac fibroblast development,biological_process
80886,GO:0060941,The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,epicardium-derived cardiac fibroblast cell fate commitment,biological_process
80887,GO:0060942,The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,neural crest-derived cardiac fibroblast cell differentiation,biological_process
80888,GO:0060943,"The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.",neural crest-derived cardiac fibroblast cell development,biological_process
80889,GO:0060944,The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.,neural crest-derived cardiac fibroblast cell fate commitment,biological_process
80890,GO:0060945,The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.,cardiac neuron differentiation,biological_process
80891,GO:0060946,The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.,cardiac blood vessel endothelial cell differentiation,biological_process
80892,GO:0060947,The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.,cardiac vascular smooth muscle cell differentiation,biological_process
80893,GO:0060948,"The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.",cardiac vascular smooth muscle cell development,biological_process
80894,GO:0060949,The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.,cardiac vascular smooth muscle cell fate commitment,biological_process
80895,GO:0060950,The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.,cardiac glial cell differentiation,biological_process
80896,GO:0060951,The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.,neural crest-derived cardiac glial cell differentiation,biological_process
80897,GO:0060952,"The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.",cardiac glial cell development,biological_process
80898,GO:0060953,The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.,cardiac glial cell fate commitment,biological_process
80899,GO:0060954,"The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",neural crest-derived cardiac glial cell development,biological_process
80900,GO:0060955,The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.,neural crest-derived cardiac glial cell fate commitment,biological_process
80901,GO:0060956,"The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.",endocardial cell differentiation,biological_process
80902,GO:0060957,The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.,endocardial cell fate commitment,biological_process
80903,GO:0060958,"The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.",endocardial cell development,biological_process
80904,GO:0060959,"The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.",cardiac neuron development,biological_process
80905,GO:0060960,The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.,cardiac neuron fate commitment,biological_process
80906,GO:0060961,"Binds to and stops, prevents or reduces the activity of phospholipase D.",phospholipase D inhibitor activity,molecular_function
80907,GO:0060962,"Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.",regulation of ribosomal protein gene transcription by RNA polymerase II,biological_process
80908,GO:0060963,"Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.",positive regulation of ribosomal protein gene transcription by RNA polymerase II,biological_process
80909,GO:0060964,"A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs).",regulation of miRNA-mediated gene silencing,biological_process
80910,GO:0060965,"A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA).",negative regulation of miRNA-mediated gene silencing,biological_process
80911,GO:0060966,"Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.",regulation of gene silencing by regulatory ncRNA,biological_process
80912,GO:0060967,"Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.",negative regulation of gene silencing by regulatory ncRNA,biological_process
80913,GO:0060970,The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.,embryonic heart tube dorsal/ventral pattern formation,biological_process
80914,GO:0060971,The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.,embryonic heart tube left/right pattern formation,biological_process
80915,GO:0060972,The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.,left/right pattern formation,biological_process
80916,GO:0060973,"The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.",cell migration involved in heart development,biological_process
80917,GO:0060974,The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.,cell migration involved in heart formation,biological_process
80918,GO:0060975,"The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.",cardioblast migration to the midline involved in heart field formation,biological_process
80919,GO:0060976,"The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.",coronary vasculature development,biological_process
80920,GO:0060977,The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.,coronary vasculature morphogenesis,biological_process
80921,GO:0060978,Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.,angiogenesis involved in coronary vascular morphogenesis,biological_process
80922,GO:0060979,"The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.",vasculogenesis involved in coronary vascular morphogenesis,biological_process
80923,GO:0060980,The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.,cell migration involved in coronary vasculogenesis,biological_process
80924,GO:0060981,The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.,cell migration involved in coronary angiogenesis,biological_process
80925,GO:0060982,The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.,coronary artery morphogenesis,biological_process
80926,GO:0060983,The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.,epicardium-derived cardiac vascular smooth muscle cell differentiation,biological_process
80927,GO:0060984,"The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.",epicardium-derived cardiac vascular smooth muscle cell development,biological_process
80928,GO:0060985,The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.,epicardium-derived cardiac vascular smooth muscle cell fate commitment,biological_process
80929,GO:0060987,A macromolecular complex that contains a tube of lipid surrounded by a protein coat.,lipid tube,cellular_component
80930,GO:0060988,"The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.",lipid tube assembly,biological_process
80931,GO:0060989,"The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.",lipid tube assembly involved in organelle fusion,biological_process
80932,GO:0060990,"The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.",lipid tube assembly involved in organelle fission,biological_process
80933,GO:0060992,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.",response to fungicide,biological_process
80934,GO:0060993,Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.,kidney morphogenesis,biological_process
80935,GO:0060996,"The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.",dendritic spine development,biological_process
80936,GO:0060997,The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.,dendritic spine morphogenesis,biological_process
80937,GO:0060998,"Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.",regulation of dendritic spine development,biological_process
80938,GO:0060999,"Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.",positive regulation of dendritic spine development,biological_process
80939,GO:0061000,"Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.",negative regulation of dendritic spine development,biological_process
80940,GO:0061001,"Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.",regulation of dendritic spine morphogenesis,biological_process
80941,GO:0061002,"Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.",negative regulation of dendritic spine morphogenesis,biological_process
80942,GO:0061003,"Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.",positive regulation of dendritic spine morphogenesis,biological_process
80943,GO:0061005,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.,cell differentiation involved in kidney development,biological_process
80944,GO:0061006,"Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.",regulation of cell proliferation involved in kidney morphogenesis,biological_process
80945,GO:0061007,"A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.",hepaticobiliary system process,biological_process
80946,GO:0061008,"The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.",hepaticobiliary system development,biological_process
80947,GO:0061009,"The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine.",common bile duct development,biological_process
80948,GO:0061010,"The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile.",gallbladder development,biological_process
80949,GO:0061011,"The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.",hepatic duct development,biological_process
80950,GO:0061013,"Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.",regulation of mRNA catabolic process,biological_process
80951,GO:0061014,"Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.",positive regulation of mRNA catabolic process,biological_process
80952,GO:0061015,"The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.",snRNA import into nucleus,biological_process
80953,GO:0061016,"The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.",snRNA localization to Cajal body,biological_process
80954,GO:0061017,The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.,hepatoblast differentiation,biological_process
80955,GO:0061024,"A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.",membrane organization,biological_process
80956,GO:0061025,The membrane organization process that joins two lipid bilayers to form a single membrane.,membrane fusion,biological_process
80957,GO:0061026,The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.,cardiac muscle tissue regeneration,biological_process
80958,GO:0061027,"The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.",umbilical cord development,biological_process
80959,GO:0061028,"The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.",establishment of endothelial barrier,biological_process
80960,GO:0061029,The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.,eyelid development in camera-type eye,biological_process
80961,GO:0061030,The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.,epithelial cell differentiation involved in mammary gland alveolus development,biological_process
80962,GO:0061031,The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.,endodermal digestive tract morphogenesis,biological_process
80963,GO:0061032,The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.,visceral serous pericardium development,biological_process
80964,GO:0061033,The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.,secretion by lung epithelial cell involved in lung growth,biological_process
80965,GO:0061034,The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.,olfactory bulb mitral cell layer development,biological_process
80966,GO:0061035,"Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",regulation of cartilage development,biological_process
80967,GO:0061036,"Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",positive regulation of cartilage development,biological_process
80968,GO:0061037,"Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.",negative regulation of cartilage development,biological_process
80969,GO:0061038,The process in which anatomical structures of the uterus are generated and organized.,uterus morphogenesis,biological_process
80970,GO:0061040,The process in which a female gonad is generated and organized.,female gonad morphogenesis,biological_process
80971,GO:0061041,"Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.",regulation of wound healing,biological_process
80972,GO:0061042,Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.,vascular wound healing,biological_process
80973,GO:0061043,"Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.",regulation of vascular wound healing,biological_process
80974,GO:0061044,"Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.",negative regulation of vascular wound healing,biological_process
80975,GO:0061045,"Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.",negative regulation of wound healing,biological_process
80976,GO:0061046,"Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.",regulation of branching involved in lung morphogenesis,biological_process
80977,GO:0061047,"Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.",positive regulation of branching involved in lung morphogenesis,biological_process
80978,GO:0061048,"Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.",negative regulation of branching involved in lung morphogenesis,biological_process
80979,GO:0061049,"The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.",cell growth involved in cardiac muscle cell development,biological_process
80980,GO:0061050,"Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.",regulation of cell growth involved in cardiac muscle cell development,biological_process
80981,GO:0061051,"Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.",positive regulation of cell growth involved in cardiac muscle cell development,biological_process
80982,GO:0061052,"Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.",negative regulation of cell growth involved in cardiac muscle cell development,biological_process
80983,GO:0061053,The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.,somite development,biological_process
80984,GO:0061054,"The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.",dermatome development,biological_process
80985,GO:0061055,"The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.",myotome development,biological_process
80986,GO:0061056,"The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.",sclerotome development,biological_process
80987,GO:0061057,The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.,peptidoglycan recognition protein signaling pathway,biological_process
80988,GO:0061058,"Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.",regulation of peptidoglycan recognition protein signaling pathway,biological_process
80989,GO:0061059,"Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.",positive regulation of peptidoglycan recognition protein signaling pathway,biological_process
80990,GO:0061060,"Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.",negative regulation of peptidoglycan recognition protein signaling pathway,biological_process
80991,GO:0061061,"The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.",muscle structure development,biological_process
80992,GO:0061062,"Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific ce...",regulation of nematode larval development,biological_process
80993,GO:0061063,"Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific ce...",positive regulation of nematode larval development,biological_process
80994,GO:0061064,"Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific ce...",negative regulation of nematode larval development,biological_process
80995,GO:0061065,"Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.",regulation of dauer larval development,biological_process
80996,GO:0061066,"Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.",positive regulation of dauer larval development,biological_process
80997,GO:0061067,"Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.",negative regulation of dauer larval development,biological_process
80998,GO:0061068,The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.,urethra development,biological_process
80999,GO:0061069,The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.,male urethra development,biological_process
81000,GO:0061070,"The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.",female urethra development,biological_process
81001,GO:0061071,"The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.",urethra epithelium development,biological_process
81002,GO:0061072,The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.,iris morphogenesis,biological_process
81003,GO:0061073,The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.,ciliary body morphogenesis,biological_process
81004,GO:0061074,"Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.",regulation of neural retina development,biological_process
81005,GO:0061075,"Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.",positive regulation of neural retina development,biological_process
81006,GO:0061076,"Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.",negative regulation of neural retina development,biological_process
81007,GO:0061079,The progression of the left horn of the sinus venosus from its initial formation to the mature structure.,left horn of sinus venosus development,biological_process
81008,GO:0061080,The progression of the right horn of the sinus venosus from its formation to the mature structure.,right horn of sinus venosus development,biological_process
81009,GO:0061081,"Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.",positive regulation of myeloid leukocyte cytokine production involved in immune response,biological_process
81010,GO:0061082,Any process that contributes to cytokine production by a myeloid cell.,myeloid leukocyte cytokine production,biological_process
81011,GO:0061083,"Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.",regulation of protein refolding,biological_process
81012,GO:0061084,"Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.",negative regulation of protein refolding,biological_process
81013,GO:0061091,"Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.",regulation of phospholipid translocation,biological_process
81014,GO:0061092,"Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.",positive regulation of phospholipid translocation,biological_process
81015,GO:0061093,"Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.",negative regulation of phospholipid translocation,biological_process
81016,GO:0061094,"Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.",regulation of turning behavior involved in mating,biological_process
81017,GO:0061096,"Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.",negative regulation of turning behavior involved in mating,biological_process
81018,GO:0061097,"Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.",regulation of protein tyrosine kinase activity,biological_process
81019,GO:0061098,"Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.",positive regulation of protein tyrosine kinase activity,biological_process
81020,GO:0061099,"Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.",negative regulation of protein tyrosine kinase activity,biological_process
81021,GO:0061100,The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.,lung neuroendocrine cell differentiation,biological_process
81022,GO:0061101,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.,neuroendocrine cell differentiation,biological_process
81023,GO:0061102,The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.,stomach neuroendocrine cell differentiation,biological_process
81024,GO:0061103,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.,carotid body glomus cell differentiation,biological_process
81025,GO:0061104,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.,adrenal chromaffin cell differentiation,biological_process
81026,GO:0061105,"Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.",regulation of stomach neuroendocrine cell differentiation,biological_process
81027,GO:0061106,"Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.",negative regulation of stomach neuroendocrine cell differentiation,biological_process
81028,GO:0061107,"The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.",seminal vesicle development,biological_process
81029,GO:0061108,"The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.",seminal vesicle epithelium development,biological_process
81030,GO:0061109,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.",dense core granule organization,biological_process
81031,GO:0061110,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.",dense core granule biogenesis,biological_process
81032,GO:0061113,Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.,pancreas morphogenesis,biological_process
81033,GO:0061114,The process in which the branches of the pancreas are generated and organized.,branching involved in pancreas morphogenesis,biological_process
81034,GO:0061115,"The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.",lung proximal/distal axis specification,biological_process
81035,GO:0061116,The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.,ductus venosus closure,biological_process
81036,GO:0061117,Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.,negative regulation of heart growth,biological_process
81037,GO:0061118,"Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.",regulation of positive chemotaxis to cAMP,biological_process
81038,GO:0061119,"Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.",regulation of positive chemotaxis to cAMP by chlorinated alkylphenone,biological_process
81039,GO:0061120,"Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.",regulation of positive chemotaxis to cAMP by DIF-1,biological_process
81040,GO:0061121,"Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.",regulation of positive chemotaxis to cAMP by DIF-2,biological_process
81041,GO:0061122,"Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.",positive regulation of positive chemotaxis to cAMP,biological_process
81042,GO:0061123,"Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.",negative regulation of positive chemotaxis to cAMP,biological_process
81043,GO:0061124,"Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.",positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone,biological_process
81044,GO:0061125,"Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.",negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone,biological_process
81045,GO:0061126,"Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.",positive regulation of positive chemotaxis to cAMP by DIF-1,biological_process
81046,GO:0061127,"Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.",negative regulation of positive chemotaxis to cAMP by DIF-1,biological_process
81047,GO:0061128,"Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.",positive regulation of chemotaxis to cAMP by DIF-2,biological_process
81048,GO:0061129,"Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.",negative regulation of positive chemotaxis to cAMP by DIF-2,biological_process
81049,GO:0061130,The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.,pancreatic bud formation,biological_process
81050,GO:0061131,The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.,pancreas field specification,biological_process
81051,GO:0061132,The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.,pancreas induction,biological_process
81052,GO:0061133,Binds to and increases the activity of an endopeptidase.,endopeptidase activator activity,molecular_function
81053,GO:0061134,"Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.",peptidase regulator activity,molecular_function
81054,GO:0061135,"Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.",endopeptidase regulator activity,molecular_function
81055,GO:0061136,"Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.",regulation of proteasomal protein catabolic process,biological_process
81056,GO:0061137,The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.,bud dilation,biological_process
81057,GO:0061138,The process in which the anatomical structures of a branched epithelium are generated and organized.,morphogenesis of a branching epithelium,biological_process
81058,GO:0061139,The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,bud field specification,biological_process
81059,GO:0061140,The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.,lung secretory cell differentiation,biological_process
81060,GO:0061141,The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.,lung ciliated cell differentiation,biological_process
81061,GO:0061143,"The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.",alveolar primary septum development,biological_process
81062,GO:0061144,"The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.",alveolar secondary septum development,biological_process
81063,GO:0061145,"The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.",lung smooth muscle development,biological_process
81064,GO:0061146,The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.,Peyer's patch morphogenesis,biological_process
81065,GO:0061147,"The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.",endocardial endothelium development,biological_process
81066,GO:0061148,"A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.",extracellular matrix organization involved in endocardium development,biological_process
81067,GO:0061150,The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.,renal system segmentation,biological_process
81068,GO:0061152,The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.,trachea submucosa development,biological_process
81069,GO:0061153,"The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.",trachea gland development,biological_process
81070,GO:0061154,"The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.",endothelial tube morphogenesis,biological_process
81071,GO:0061155,The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.,pulmonary artery endothelial tube morphogenesis,biological_process
81072,GO:0061156,The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.,pulmonary artery morphogenesis,biological_process
81073,GO:0061157,"Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.",mRNA destabilization,biological_process
81074,GO:0061158,An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.,3'-UTR-mediated mRNA destabilization,biological_process
81075,GO:0061159,The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.,establishment of bipolar cell polarity involved in cell morphogenesis,biological_process
81076,GO:0061160,"Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.",regulation of establishment of bipolar cell polarity regulating cell shape,biological_process
81077,GO:0061161,"Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.",positive regulation of establishment of bipolar cell polarity regulating cell shape,biological_process
81078,GO:0061162,The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.,establishment of monopolar cell polarity,biological_process
81079,GO:0061163,The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.,endoplasmic reticulum polarization,biological_process
81080,GO:0061168,"Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.",regulation of hair follicle placode formation,biological_process
81081,GO:0061169,"Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.",positive regulation of hair placode formation,biological_process
81082,GO:0061170,"Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.",negative regulation of hair follicle placode formation,biological_process
81083,GO:0061171,The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.,establishment of bipolar cell polarity,biological_process
81084,GO:0061172,"Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.",regulation of establishment of bipolar cell polarity,biological_process
81085,GO:0061173,"Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.",positive regulation of establishment of bipolar cell polarity,biological_process
81086,GO:0061174,"Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.",type I terminal bouton,cellular_component
81087,GO:0061175,"Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.",type II terminal bouton,cellular_component
81088,GO:0061176,"Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.",type Ib terminal bouton,cellular_component
81089,GO:0061177,"Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.",type Is terminal bouton,cellular_component
81090,GO:0061178,"Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.",regulation of insulin secretion involved in cellular response to glucose stimulus,biological_process
81091,GO:0061179,"Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.",negative regulation of insulin secretion involved in cellular response to glucose stimulus,biological_process
81092,GO:0061180,"The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.",mammary gland epithelium development,biological_process
81093,GO:0061181,"Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.",regulation of chondrocyte development,biological_process
81094,GO:0061182,"Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.",negative regulation of chondrocyte development,biological_process
81095,GO:0061183,"Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.",regulation of dermatome development,biological_process
81096,GO:0061184,"Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.",positive regulation of dermatome development,biological_process
81097,GO:0061185,"Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.",negative regulation of dermatome development,biological_process
81098,GO:0061186,"Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.",negative regulation of silent mating-type cassette heterochromatin formation,biological_process
81099,GO:0061187,"Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation.",regulation of rDNA heterochromatin formation,biological_process
81100,GO:0061188,"Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation.",negative regulation of rDNA heterochromatin formation,biological_process
81101,GO:0061189,"Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.",positive regulation of sclerotome development,biological_process
81102,GO:0061190,"Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.",regulation of sclerotome development,biological_process
81103,GO:0061191,"Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.","positive regulation of vacuole fusion, non-autophagic",biological_process
81104,GO:0061192,"Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.","negative regulation of vacuole fusion, non-autophagic",biological_process
81105,GO:0061193,"The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.",taste bud development,biological_process
81106,GO:0061194,The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.,taste bud morphogenesis,biological_process
81107,GO:0061195,The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.,taste bud formation,biological_process
81108,GO:0061196,"The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.",fungiform papilla development,biological_process
81109,GO:0061197,The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.,fungiform papilla morphogenesis,biological_process
81110,GO:0061198,The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.,fungiform papilla formation,biological_process
81111,GO:0061199,"The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.",striated muscle contraction involved in embryonic body morphogenesis,biological_process
81112,GO:0061200,A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.,clathrin-sculpted gamma-aminobutyric acid transport vesicle,cellular_component
81113,GO:0061201,The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.,clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen,cellular_component
81114,GO:0061202,The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.,clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane,cellular_component
81115,GO:0061203,"The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.",striated muscle paramyosin thick filament assembly,biological_process
81116,GO:0061204,The formation or disassembly of a filament composed of paramyosin molecules.,paramyosin filament assembly or disassembly,biological_process
81117,GO:0061205,"The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts ...",paramesonephric duct development,biological_process
81118,GO:0061206,The process in which the anatomical structures of the mesonephros are generated and organized.,mesonephros morphogenesis,biological_process
81119,GO:0061207,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.,mesonephric juxtaglomerulus cell differentiation,biological_process
81120,GO:0061211,"The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.",mesonephric collecting duct development,biological_process
81121,GO:0061212,"The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.",mesonephric juxtaglomerular apparatus development,biological_process
81122,GO:0061213,"Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",positive regulation of mesonephros development,biological_process
81123,GO:0061214,"The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.",mesonephric smooth muscle tissue development,biological_process
81124,GO:0061215,"The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.",mesonephric nephron development,biological_process
81125,GO:0061217,"Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.",regulation of mesonephros development,biological_process
81126,GO:0061218,"Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",negative regulation of mesonephros development,biological_process
81127,GO:0061219,The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.,mesonephric mesenchyme development,biological_process
81128,GO:0061220,"The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.",mesonephric macula densa development,biological_process
81129,GO:0061221,The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.,mesonephric mesenchyme morphogenesis,biological_process
81130,GO:0061223,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.,mesonephric mesenchymal cell differentiation,biological_process
81131,GO:0061224,"The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.",mesonephric glomerulus development,biological_process
81132,GO:0061228,The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.,mesonephric nephron morphogenesis,biological_process
81133,GO:0061229,"The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.",mesonephric juxtaglomerulus cell development,biological_process
81134,GO:0061230,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.,mesonephric juxtaglomerulus cell fate commitment,biological_process
81135,GO:0061231,The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.,mesonephric glomerulus vasculature development,biological_process
81136,GO:0061232,"The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to pro...",mesonephric glomerular epithelium development,biological_process
81137,GO:0061233,"The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.",mesonephric glomerular basement membrane development,biological_process
81138,GO:0061234,The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.,mesonephric glomerulus morphogenesis,biological_process
81139,GO:0061236,The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.,mesonephric comma-shaped body morphogenesis,biological_process
81140,GO:0061240,"The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.",mesonephric nephron tubule morphogenesis,biological_process
81141,GO:0061241,"The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.",mesonephric nephron epithelium development,biological_process
81142,GO:0061242,"The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.",mesonephric nephron tubule development,biological_process
81143,GO:0061243,"The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.",mesonephric renal vesicle morphogenesis,biological_process
81144,GO:0061244,The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.,mesonephric S-shaped body morphogenesis,biological_process
81145,GO:0061245,"Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.",establishment or maintenance of bipolar cell polarity,biological_process
81146,GO:0061246,"Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.",establishment or maintenance of bipolar cell polarity regulating cell shape,biological_process
81147,GO:0061247,"The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.",mesonephric glomerular mesangium development,biological_process
81148,GO:0061248,The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.,mesonephric glomerulus vasculature morphogenesis,biological_process
81149,GO:0061249,The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.,mesonephric glomerular capillary formation,biological_process
81150,GO:0061250,"The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.",mesonephric glomerular epithelial cell differentiation,biological_process
81151,GO:0061251,"The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.",mesonephric glomerular epithelial cell development,biological_process
81152,GO:0061252,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.",mesonephric glomerular epithelial cell fate commitment,biological_process
81153,GO:0061253,The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.,mesonephric glomerular parietal epithelial cell differentiation,biological_process
81154,GO:0061254,"The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.",mesonephric glomerular parietal epithelial cell development,biological_process
81155,GO:0061255,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.,mesonephric glomerular parietal epithelial cell fate commitment,biological_process
81156,GO:0061256,The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.,mesonephric podocyte differentiation,biological_process
81157,GO:0061257,"The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.",mesonephric podocyte development,biological_process
81158,GO:0061258,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.,mesonephric podocyte cell fate commitment,biological_process
81159,GO:0061259,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.,mesonephric glomerular mesangial cell differentiation,biological_process
81160,GO:0061260,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.,mesonephric mesangial cell differentiation,biological_process
81161,GO:0061262,The developmental process pertaining to the initial formation of the mesonephros.,mesonephric renal vesicle formation,biological_process
81162,GO:0061263,"The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.",mesonephric glomerular mesangial cell development,biological_process
81163,GO:0061264,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.,mesonephric glomerular mesangial cell fate commitment,biological_process
81164,GO:0061265,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.,mesonephric nephron tubule epithelial cell differentiation,biological_process
81165,GO:0061266,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.,mesonephric interstitial fibroblast differentiation,biological_process
81166,GO:0061267,"The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.",mesonephric interstitial fibroblast development,biological_process
81167,GO:0061268,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.,mesonephric interstitial fibroblast fate commitment,biological_process
81168,GO:0061270,"The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.",mesonephric intraglomerular mesangial cell proliferation,biological_process
81169,GO:0061272,"The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.",mesonephric connecting tubule development,biological_process
81170,GO:0061273,The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.,mesonephric distal tubule morphogenesis,biological_process
81171,GO:0061274,"The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.",mesonephric distal tubule development,biological_process
81172,GO:0061275,"The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.",mesonephric proximal tubule development,biological_process
81173,GO:0061276,The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.,mesonephric proximal tubule morphogenesis,biological_process
81174,GO:0061277,The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.,mesonephric nephron tubule formation,biological_process
81175,GO:0061281,The process in which the connecting tubule of the mesonephric nephron acquires its identity.,specification of mesonephric connecting tubule identity,biological_process
81176,GO:0061282,The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.,specification of mesonephric nephron tubule identity,biological_process
81177,GO:0061283,The process in which the distal tubule of the mesonephric nephron acquires its identity.,specification of mesonephric distal tubule identity,biological_process
81178,GO:0061284,The process in which the proximal tubule of the mesonephric nephron acquires its identity.,specification of mesonephric proximal tubule identity,biological_process
81179,GO:0061285,"The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.",mesonephric capsule development,biological_process
81180,GO:0061286,"The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.",mesonephric capsule morphogenesis,biological_process
81181,GO:0061287,"The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.",mesonephric capsule formation,biological_process
81182,GO:0061288,The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,mesonephric capsule specification,biological_process
81183,GO:0061294,Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.,mesonephric renal vesicle induction,biological_process
81184,GO:0061298,"The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.",retina vasculature development in camera-type eye,biological_process
81185,GO:0061299,The process in which the vasculature of the retina is generated and organized.,retina vasculature morphogenesis in camera-type eye,biological_process
81186,GO:0061300,"The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.",cerebellum vasculature development,biological_process
81187,GO:0061301,The process in which the vasculature of the cerebellum is generated and organized.,cerebellum vasculature morphogenesis,biological_process
81188,GO:0061302,The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.,smooth muscle cell-matrix adhesion,biological_process
81189,GO:0061303,"The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.",cornea development in camera-type eye,biological_process
81190,GO:0061304,"The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.",retinal blood vessel morphogenesis,biological_process
81191,GO:0061305,The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.,maintenance of bipolar cell polarity regulating cell shape,biological_process
81192,GO:0061307,"The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.",cardiac neural crest cell differentiation involved in heart development,biological_process
81193,GO:0061308,"The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.",cardiac neural crest cell development involved in heart development,biological_process
81194,GO:0061309,"The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.",cardiac neural crest cell development involved in outflow tract morphogenesis,biological_process
81195,GO:0061311,"The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.",cell surface receptor signaling pathway involved in heart development,biological_process
81196,GO:0061314,The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.,Notch signaling involved in heart development,biological_process
81197,GO:0061316,"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stab...",canonical Wnt signaling pathway involved in heart development,biological_process
81198,GO:0061318,"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.",renal filtration cell differentiation,biological_process
81199,GO:0061319,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.,nephrocyte differentiation,biological_process
81200,GO:0061320,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.,pericardial nephrocyte differentiation,biological_process
81201,GO:0061321,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.,garland nephrocyte differentiation,biological_process
81202,GO:0061322,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.,disseminated nephrocyte differentiation,biological_process
81203,GO:0061323,"The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.",cell proliferation involved in heart morphogenesis,biological_process
81204,GO:0061325,"The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.",cell proliferation involved in outflow tract morphogenesis,biological_process
81205,GO:0061326,"The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.",renal tubule development,biological_process
81206,GO:0061327,"The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.",anterior Malpighian tubule development,biological_process
81207,GO:0061328,"The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.",posterior Malpighian tubule development,biological_process
81208,GO:0061329,The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.,Malpighian tubule principal cell differentiation,biological_process
81209,GO:0061330,The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.,Malpighian tubule stellate cell differentiation,biological_process
81210,GO:0061331,"The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.",epithelial cell proliferation involved in Malpighian tubule morphogenesis,biological_process
81211,GO:0061332,The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.,Malpighian tubule bud morphogenesis,biological_process
81212,GO:0061333,"The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.",renal tubule morphogenesis,biological_process
81213,GO:0061334,The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.,cell rearrangement involved in Malpighian tubule morphogenesis,biological_process
81214,GO:0061336,The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.,cell morphogenesis involved in Malpighian tubule morphogenesis,biological_process
81215,GO:0061337,"Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.",cardiac conduction,biological_process
81216,GO:0061339,"Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.",establishment or maintenance of monopolar cell polarity,biological_process
81217,GO:0061340,"Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.",establishment or maintenance of monopolar cell polarity regulating cell shape,biological_process
81218,GO:0061341,"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.",non-canonical Wnt signaling pathway involved in heart development,biological_process
81219,GO:0061343,"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.",cell adhesion involved in heart morphogenesis,biological_process
81220,GO:0061344,Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.,regulation of cell adhesion involved in heart morphogenesis,biological_process
81221,GO:0061351,"The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.",neural precursor cell proliferation,biological_process
81222,GO:0061352,The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.,cell chemotaxis involved in Malpighian tubule morphogenesis,biological_process
81223,GO:0061355,The controlled release of a Wnt protein from a cell.,Wnt protein secretion,biological_process
81224,GO:0061356,"Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.",regulation of Wnt protein secretion,biological_process
81225,GO:0061357,"Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.",positive regulation of Wnt protein secretion,biological_process
81226,GO:0061358,"Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.",negative regulation of Wnt protein secretion,biological_process
81227,GO:0061360,The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.,optic chiasma development,biological_process
81228,GO:0061361,"Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.",positive regulation of maintenance of bipolar cell polarity regulating cell shape,biological_process
81229,GO:0061362,"Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.",negative regulation of maintenance of bipolar cell polarity regulating cell shape,biological_process
81230,GO:0061364,The apoptotic process that contributes to luteolysis.,apoptotic process involved in luteolysis,biological_process
81231,GO:0061365,Any process that increases the activity of triglyceride lipase.,positive regulation of triglyceride lipase activity,biological_process
81232,GO:0061366,Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.,behavioral response to chemical pain,biological_process
81233,GO:0061367,Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.,behavioral response to acetic acid induced pain,biological_process
81234,GO:0061368,Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.,behavioral response to formalin induced pain,biological_process
81235,GO:0061369,"Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.",negative regulation of testicular blood vessel morphogenesis,biological_process
81236,GO:0061370,"The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.",testosterone biosynthetic process,biological_process
81237,GO:0061371,Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.,determination of heart left/right asymmetry,biological_process
81238,GO:0061373,"The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.",mammillary axonal complex development,biological_process
81239,GO:0061374,"The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.",mammillothalamic axonal tract development,biological_process
81240,GO:0061375,"The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.",mammillotectal axonal tract development,biological_process
81241,GO:0061376,"The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.",mammillotegmental axonal tract development,biological_process
81242,GO:0061377,"The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.",mammary gland lobule development,biological_process
81243,GO:0061378,"The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.",corpora quadrigemina development,biological_process
81244,GO:0061379,"The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surroun...",inferior colliculus development,biological_process
81245,GO:0061380,"The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.",superior colliculus development,biological_process
81246,GO:0061381,The orderly movement of a cell that will reside in the diencephalon.,cell migration in diencephalon,biological_process
81247,GO:0061382,The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.,Malpighian tubule tip cell differentiation,biological_process
81248,GO:0061383,"The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.",trabecula morphogenesis,biological_process
81249,GO:0061384,"The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.",heart trabecula morphogenesis,biological_process
81250,GO:0061386,The closure of the temporary ventral gap in the optic cup that contributes to its shaping.,closure of optic fissure,biological_process
81251,GO:0061387,Any process that modulates the extent of cell growth.,regulation of extent of cell growth,biological_process
81252,GO:0061388,Any process that modulates the rate of cell growth.,regulation of rate of cell growth,biological_process
81253,GO:0061389,Any process that modulates the direction of cell growth.,regulation of direction of cell growth,biological_process
81254,GO:0061390,Any process that increases the direction of cell growth.,positive regulation of direction of cell growth,biological_process
81255,GO:0061391,Any process that decreases the direction of cell growth.,negative regulation of direction of cell growth,biological_process
81256,GO:0061429,"Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.",positive regulation of transcription from RNA polymerase II promoter by oleic acid,biological_process
81257,GO:0061430,"The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.",bone trabecula morphogenesis,biological_process
81258,GO:0061431,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.",cellular response to methionine,biological_process
81259,GO:0061433,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.",cellular response to caloric restriction,biological_process
81260,GO:0061435,"Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.",positive regulation of transcription from a mobile element promoter,biological_process
81261,GO:0061436,"Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.",establishment of skin barrier,biological_process
81262,GO:0061437,"The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.",renal system vasculature development,biological_process
81263,GO:0061438,The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.,renal system vasculature morphogenesis,biological_process
81264,GO:0061439,The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.,kidney vasculature morphogenesis,biological_process
81265,GO:0061440,"The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.",kidney vasculature development,biological_process
81266,GO:0061441,The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.,renal artery morphogenesis,biological_process
81267,GO:0061442,"The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.",cardiac muscle cell fate determination,biological_process
81268,GO:0061443,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.,endocardial cushion cell differentiation,biological_process
81269,GO:0061444,"The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.",endocardial cushion cell development,biological_process
81270,GO:0061445,The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.,endocardial cushion cell fate commitment,biological_process
81271,GO:0061446,"The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.",endocardial cushion cell fate determination,biological_process
81272,GO:0061447,"The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.",endocardial cushion cell fate specification,biological_process
81273,GO:0061448,"The progression of a connective tissue over time, from its formation to the mature structure.",connective tissue development,biological_process
81274,GO:0061449,"The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",olfactory bulb tufted cell development,biological_process
81275,GO:0061450,Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.,trophoblast cell migration,biological_process
81276,GO:0061451,"The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.",retrotrapezoid nucleus development,biological_process
81277,GO:0061452,The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.,retrotrapezoid nucleus neuron differentiation,biological_process
81278,GO:0061453,The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.,interstitial cell of Cajal differentiation,biological_process
81279,GO:0061454,The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.,release of sequestered calcium ion into cytosol by Golgi,biological_process
81280,GO:0061458,The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.,reproductive system development,biological_process
81281,GO:0061459,Enables the transfer of L-arginine from one side of a membrane to the other.,L-arginine transmembrane transporter activity,molecular_function
81282,GO:0061462,"A process in which a protein is transported to, or maintained in, a location within a lysosome.",protein localization to lysosome,biological_process
81283,GO:0061463,Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate. Removes the acetyl group from either the 2'' or 3'' position of O-acetyl-ADP-ribose.,O-acetyl-ADP-ribose deacetylase activity,molecular_function
81284,GO:0061468,A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.,karyomere,cellular_component
81285,GO:0061469,"Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.",regulation of type B pancreatic cell proliferation,biological_process
81286,GO:0061470,The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.,T follicular helper cell differentiation,biological_process
81287,GO:0061471,The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.,karyomere assembly,biological_process
81288,GO:0061472,Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.,karyomere membrane fusion,biological_process
81289,GO:0061473,"Catalysis of the reaction: L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate (murein tripeptide) + H2O = L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate.",murein tripeptide carboxypeptidase activity,molecular_function
81290,GO:0061474,The lipid bilayer surrounding a phagolysosome.,phagolysosome membrane,cellular_component
81291,GO:0061475,"The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",cytosolic valyl-tRNA aminoacylation,biological_process
81292,GO:0061476,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.",response to anticoagulant,biological_process
81293,GO:0061477,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.",response to aromatase inhibitor,biological_process
81294,GO:0061478,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.",response to platelet aggregation inhibitor,biological_process
81295,GO:0061479,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.",response to reverse transcriptase inhibitor,biological_process
81296,GO:0061480,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.",response to asparaginase,biological_process
81297,GO:0061481,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.",response to TNF agonist,biological_process
81298,GO:0061482,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.",response to irinotecan,biological_process
81299,GO:0061484,Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.,hematopoietic stem cell homeostasis,biological_process
81300,GO:0061485,The expansion of a memory T cell population by cell division.,memory T cell proliferation,biological_process
81301,GO:0061486,Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity fructose transmembrane transporter activity,molecular_function
81302,GO:0061493,One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.,central plaque of mitotic spindle pole body,cellular_component
81303,GO:0061496,Structure adjacent to the plaques of the mitotic spindle pole body.,half bridge of mitotic spindle pole body,cellular_component
81304,GO:0061497,One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.,inner plaque of mitotic spindle pole body,cellular_component
81305,GO:0061498,Structure between the central and outer plaques of the mitotic spindle pole body.,intermediate layer of mitotic spindle pole body,cellular_component
81306,GO:0061499,One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.,outer plaque of mitotic spindle pole body,cellular_component
81307,GO:0061501,"Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).","2',3'-cyclic GMP-AMP synthase activity",molecular_function
81308,GO:0061503,Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.,tRNA threonylcarbamoyladenosine dehydratase activity,molecular_function
81309,GO:0061504,"The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.",cyclic threonylcarbamoyladenosine biosynthetic process,biological_process
81310,GO:0061507,"Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.","2',3'-cyclic GMP-AMP binding",molecular_function
81311,GO:0061511,The centrosome organization process by which a centriole increases in length as part of the process of replication.,centriole elongation,biological_process
81312,GO:0061512,"A process in which a protein is transported to, or maintained in, a location within a cilium.",protein localization to cilium,biological_process
81313,GO:0061513,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out).,glucose 6-phosphate:phosphate antiporter activity,molecular_function
81314,GO:0061514,"The series of molecular signals initiated by interleukin-34 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-34-mediated signaling pathway,biological_process
81315,GO:0061515,"The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.",myeloid cell development,biological_process
81316,GO:0061516,The expansion of a monocyte population by cell division.,monocyte proliferation,biological_process
81317,GO:0061517,The expansion of a macrophage population by cell division.,macrophage proliferation,biological_process
81318,GO:0061518,The expansion of a microglial cell population by cell division.,microglial cell proliferation,biological_process
81319,GO:0061519,The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,macrophage homeostasis,biological_process
81320,GO:0061520,The process in which a precursor cell type acquires the specialized features of a Langerhans cell.,Langerhans cell differentiation,biological_process
81321,GO:0061521,The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.,hepatic stellate cell differentiation,biological_process
81322,GO:0061522,"Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H+.","1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity",molecular_function
81323,GO:0061523,A cellular process that results in the breakdown of a cilium.,cilium disassembly,biological_process
81324,GO:0061524,The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.,central canal development,biological_process
81325,GO:0061525,"The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.",hindgut development,biological_process
81326,GO:0061526,The regulated release of acetylcholine by a cell.,acetylcholine secretion,biological_process
81327,GO:0061527,The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.,"dopamine secretion, neurotransmission",biological_process
81328,GO:0061528,The regulated release of aspartate by a cell.,aspartate secretion,biological_process
81329,GO:0061529,The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.,"epinephrine secretion, neurotransmission",biological_process
81330,GO:0061530,The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter.,"aspartate secretion, neurotransmission",biological_process
81331,GO:0061531,The regulated release of a primary amine by a cell.,primary amine secretion,biological_process
81332,GO:0061532,"The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.","primary amine secretion, neurotransmission",biological_process
81333,GO:0061533,"The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.","norepinephrine secretion, neurotransmission",biological_process
81334,GO:0061534,"The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.","gamma-aminobutyric acid secretion, neurotransmission",biological_process
81335,GO:0061535,"The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.","glutamate secretion, neurotransmission",biological_process
81336,GO:0061536,The controlled release of glycine by a cell.,glycine secretion,biological_process
81337,GO:0061537,"The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter.","glycine secretion, neurotransmission",biological_process
81338,GO:0061538,"The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.","histamine secretion, neurotransmission",biological_process
81339,GO:0061539,The controlled release of octopamine by a cell.,octopamine secretion,biological_process
81340,GO:0061540,"The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter.","octopamine secretion, neurotransmission",biological_process
81341,GO:0061541,The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.,rhabdomere morphogenesis,biological_process
81342,GO:0061542,Catalysis of the reaction: a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H+.,3-demethylubiquinol 3-O-methyltransferase activity,molecular_function
81343,GO:0061544,The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter.,"peptide secretion, neurotransmission",biological_process
81344,GO:0061545,The regulated release of a tyramine by a cell.,tyramine secretion,biological_process
81345,GO:0061546,The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter.,"tyramine secretion, neurotransmission",biological_process
81346,GO:0061547,"Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.","glycogen synthase activity, transferring glucose-1-phosphate",molecular_function
81347,GO:0061548,"The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.",ganglion development,biological_process
81348,GO:0061549,"The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.",sympathetic ganglion development,biological_process
81349,GO:0061550,"The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.",cranial ganglion development,biological_process
81350,GO:0061551,"The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.",trigeminal ganglion development,biological_process
81351,GO:0061552,The process in which the anatomical structures of ganglion are generated and organized.,ganglion morphogenesis,biological_process
81352,GO:0061553,"A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.",ganglion maturation,biological_process
81353,GO:0061554,The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.,ganglion formation,biological_process
81354,GO:0061555,The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.,ganglion structural organization,biological_process
81355,GO:0061556,The process in which the anatomical structure of a trigeminal ganglion is generated and organized.,trigeminal ganglion morphogenesis,biological_process
81356,GO:0061557,"A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.",trigeminal ganglion maturation,biological_process
81357,GO:0061558,"A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.",cranial ganglion maturation,biological_process
81358,GO:0061559,The process in which the anatomical structure of a cranial ganglion is generated and organized.,cranial ganglion morphogenesis,biological_process
81359,GO:0061560,The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.,cranial ganglion formation,biological_process
81360,GO:0061561,The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.,trigeminal ganglion formation,biological_process
81361,GO:0061562,The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.,cranial ganglion structural organization,biological_process
81362,GO:0061563,The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.,trigeminal ganglion structural organization,biological_process
81363,GO:0061564,"The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).",axon development,biological_process
81364,GO:0061565,"The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.",dAMP phosphorylation,biological_process
81365,GO:0061566,"The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.",CMP phosphorylation,biological_process
81366,GO:0061567,"The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.",dCMP phosphorylation,biological_process
81367,GO:0061572,"A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.",actin filament bundle organization,biological_process
81368,GO:0061573,A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.,actin filament bundle retrograde transport,biological_process
81369,GO:0061574,"A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.",ASAP complex,cellular_component
81370,GO:0061575,Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.,cyclin-dependent protein serine/threonine kinase activator activity,molecular_function
81371,GO:0061576,"A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.",acyl-CoA ceramide synthase complex,cellular_component
81372,GO:0061577,A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.,calcium ion transmembrane transport via high voltage-gated calcium channel,biological_process
81373,GO:0061578,Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys63 residue of ubiquitin.,K63-linked deubiquitinase activity,molecular_function
81374,GO:0061579,Catalysis of the reaction: a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H+.,N-acyl homoserine lactone synthase activity,molecular_function
81375,GO:0061580,"The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.",colon epithelial cell migration,biological_process
81376,GO:0061581,"The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.",corneal epithelial cell migration,biological_process
81377,GO:0061582,"The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.",intestinal epithelial cell migration,biological_process
81378,GO:0061583,The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,colon epithelial cell chemotaxis,biological_process
81379,GO:0061584,The controlled release of orexin from a cell or a tissue.,orexin secretion,biological_process
81380,GO:0061585,The controlled release of orexin from a cell in which orexin acts as a neurotransmitter.,"orexin secretion, neurotransmission",biological_process
81381,GO:0061586,"Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.",positive regulation of transcription by transcription factor localization,biological_process
81382,GO:0061588,The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.,calcium activated phospholipid scrambling,biological_process
81383,GO:0061589,The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.,calcium activated phosphatidylserine scrambling,biological_process
81384,GO:0061590,The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.,calcium activated phosphatidylcholine scrambling,biological_process
81385,GO:0061591,The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.,calcium activated galactosylceramide scrambling,biological_process
81386,GO:0061593,Catalysis of the reaction: 6-sulfo-beta-D-quinovose = 6-deoxy-6-sulfo-D-fructose.,sulfoquinovose isomerase activity,molecular_function
81387,GO:0061594,Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.,6-deoxy-6-sulfofructose kinase activity,molecular_function
81388,GO:0061595,Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.,6-deoxy-6-sulfofructose-1-phosphate aldolase activity,molecular_function
81389,GO:0061596,"Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.",3-sulfolactaldehyde reductase activity,molecular_function
81390,GO:0061598,Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.,molybdopterin adenylyltransferase activity,molecular_function
81391,GO:0061599,Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.,molybdopterin molybdotransferase activity,molecular_function
81392,GO:0061602,Catalysis of the reaction: Mo-molybdopterin + CTP + H+ = Mo-molybdopterin cytosine dinucleotide + diphosphate.,molybdenum cofactor cytidylyltransferase activity,molecular_function
81393,GO:0061603,Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.,molybdenum cofactor guanylyltransferase activity,molecular_function
81394,GO:0061604,Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.,molybdopterin-synthase sulfurtransferase activity,molecular_function
81395,GO:0061605,Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.,molybdopterin-synthase adenylyltransferase activity,molecular_function
81396,GO:0061606,The propionylation of the N-terminal amino acid of proteins.,N-terminal protein amino acid propionylation,biological_process
81397,GO:0061607,Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.,peptide alpha-N-propionyltransferase activity,molecular_function
81398,GO:0061608,"Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.",nuclear import signal receptor activity,molecular_function
81399,GO:0061609,Catalysis of the reaction: beta-D-fructose-1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate.,fructose-1-phosphate aldolase activity,molecular_function
81400,GO:0061611,"The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.",mannose to fructose-6-phosphate catabolic process,biological_process
81401,GO:0061614,The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation.,miRNA transcription,biological_process
81402,GO:0061615,"The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.",glycolytic process through fructose-6-phosphate,biological_process
81403,GO:0061616,The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.,glycolytic process from fructose through fructose-6-phosphate,biological_process
81404,GO:0061617,"Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.",MICOS complex,cellular_component
81405,GO:0061619,"The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.",glycolytic process from mannose through fructose-6-phosphate,biological_process
81406,GO:0061620,"The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.",glycolytic process through glucose-6-phosphate,biological_process
81407,GO:0061621,"The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.",canonical glycolysis,biological_process
81408,GO:0061622,"The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.",glycolytic process through glucose-1-phosphate,biological_process
81409,GO:0061623,"The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.",glycolytic process from galactose,biological_process
81410,GO:0061625,"The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.",glycolytic process through fructose-1-phosphate,biological_process
81411,GO:0061626,"The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.",pharyngeal arch artery morphogenesis,biological_process
81412,GO:0061627,Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.,S-methylmethionine-homocysteine S-methyltransferase activity,molecular_function
81413,GO:0061628,A histone reader that recognizes a histone H3 trimethylated at lysine 27.,histone H3K27me3 reader activity,molecular_function
81414,GO:0061629,"Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.",RNA polymerase II-specific DNA-binding transcription factor binding,molecular_function
81415,GO:0061630,"Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of...",ubiquitin protein ligase activity,molecular_function
81416,GO:0061631,"Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y = Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.",ubiquitin conjugating enzyme activity,molecular_function
81417,GO:0061632,Binds to and increases the activity of an RNA lariat debranching enzyme.,RNA lariat debranching enzyme activator activity,molecular_function
81418,GO:0061633,"The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.",transport-coupled glycolytic process through glucose-6-phosphate,biological_process
81419,GO:0061634,"Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.",alpha-D-xyloside xylohydrolase activity,molecular_function
81420,GO:0061635,Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.,regulation of protein complex stability,biological_process
81421,GO:0061638,"The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.",CENP-A containing chromatin,cellular_component
81422,GO:0061639,"A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.",Cdv-dependent cytokinesis,biological_process
81423,GO:0061640,A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.,cytoskeleton-dependent cytokinesis,biological_process
81424,GO:0061642,The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.,chemoattraction of axon,biological_process
81425,GO:0061643,The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.,chemorepulsion of axon,biological_process
81426,GO:0061644,"Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.",protein localization to CENP-A containing chromatin,biological_process
81427,GO:0061645,The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle.,endocytic patch,cellular_component
81428,GO:0061646,"Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.",positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization,biological_process
81429,GO:0061648,The process whose specific outcome is the replacement of an existing tooth with another tooth.,tooth replacement,biological_process
81430,GO:0061649,A histone reader that recognizes a histone bearing a ubiquinated lysine residue.,ubiquitin-modified histone reader activity,molecular_function
81431,GO:0061650,"Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.",ubiquitin-like protein conjugating enzyme activity,molecular_function
81432,GO:0061651,"Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.",Atg12 conjugating enzyme activity,molecular_function
81433,GO:0061652,"Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.",FAT10 conjugating enzyme activity,molecular_function
81434,GO:0061653,"Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.",ISG15 conjugating enzyme activity,molecular_function
81435,GO:0061654,"Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.",NEDD8 conjugating enzyme activity,molecular_function
81436,GO:0061655,"Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.",Pup conjugating enzyme activity,molecular_function
81437,GO:0061656,"Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.",SUMO conjugating enzyme activity,molecular_function
81438,GO:0061657,"Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.",UFM1 conjugating enzyme activity,molecular_function
81439,GO:0061658,"Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y = Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.",URM1 conjugating enzyme activity,molecular_function
81440,GO:0061659,"Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.",ubiquitin-like protein ligase activity,molecular_function
81441,GO:0061660,"Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.",Atg12 ligase activity,molecular_function
81442,GO:0061661,"Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S = X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.",FAT10 ligase activity,molecular_function
81443,GO:0061662,"Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S = X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.",ISG15 ligase activity,molecular_function
81444,GO:0061663,"Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S = X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.",NEDD8 ligase activity,molecular_function
81445,GO:0061664,"Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S = X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.",Pup ligase activity,molecular_function
81446,GO:0061665,"Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.",SUMO ligase activity,molecular_function
81447,GO:0061666,"Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S = X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.",UFM1 ligase activity,molecular_function
81448,GO:0061667,"Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S = X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.",URM1 ligase activity,molecular_function
81449,GO:0061668,"The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.",mitochondrial ribosome assembly,biological_process
81450,GO:0061669,Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.,spontaneous neurotransmitter secretion,biological_process
81451,GO:0061670,Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.,evoked neurotransmitter secretion,biological_process
81452,GO:0061671,A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.,Cbp3p-Cbp6 complex,cellular_component
81453,GO:0061672,Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.,glutathione hydrolase complex,cellular_component
81454,GO:0061673,Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.,mitotic spindle astral microtubule,cellular_component
81455,GO:0061674,Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.,gap filling involved in double-strand break repair via nonhomologous end joining,biological_process
81456,GO:0061675,"Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.",RBL family protein binding,molecular_function
81457,GO:0061676,Binding to a member of the importin-alpha family.,importin-alpha family protein binding,molecular_function
81458,GO:0061677,Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate = pyruvate + D-glyceraldehyde.,2-dehydro-3-deoxy-D-gluconate aldolase activity,molecular_function
81459,GO:0061678,A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.,Entner-Doudoroff pathway,biological_process
81460,GO:0061682,The process in which the anatomical structures of a seminal vesicle are generated and organized.,seminal vesicle morphogenesis,biological_process
81461,GO:0061684,The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.,chaperone-mediated autophagy,biological_process
81462,GO:0061685,Catalysis of the reaction: diphthine methyl ester + H2O = diphthine + H+ + methanol.,diphthine methylesterase activity,molecular_function
81463,GO:0061686,"Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 = hercynylcysteine sulfoxide + H2O.",hercynylcysteine sulfoxide synthase activity,molecular_function
81464,GO:0061687,Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.,detoxification of inorganic compound,biological_process
81465,GO:0061689,An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.,tricellular tight junction,cellular_component
81466,GO:0061690,Catalysis of the reaction: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] = (R)-lipoate + L-lysyl-[lipoyl-carrier protein].,lipoamidase activity,molecular_function
81467,GO:0061691,Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.,detoxification of hydrogen peroxide,biological_process
81468,GO:0061692,Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.,cellular detoxification of hydrogen peroxide,biological_process
81469,GO:0061693,Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.,alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity,molecular_function
81470,GO:0061694,A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.,alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex,cellular_component
81471,GO:0061695,A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).,"transferase complex, transferring phosphorus-containing groups",cellular_component
81472,GO:0061696,"A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.",pituitary gonadotropin complex,cellular_component
81473,GO:0061697,Catalysis of the reaction: N(6)-glutaryl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-glutaryl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].,protein-glutaryllysine deglutarylase activity,molecular_function
81474,GO:0061698,The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.,protein deglutarylation,biological_process
81475,GO:0061700,"A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.",GATOR2 complex,cellular_component
81476,GO:0061701,"A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.",bacterial outer membrane vesicle,cellular_component
81477,GO:0061702,A cytosolic protein complex that is capable of activating caspase-1.,canonical inflammasome complex,cellular_component
81478,GO:0061703,A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.,pyroptosome complex,cellular_component
81479,GO:0061704,"The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.",glycolytic process from sucrose,biological_process
81480,GO:0061706,"The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.",glycolytic process from sucrose through glucose and fructose,biological_process
81481,GO:0061707,The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.,extracellular exosome macropinocytosis,biological_process
81482,GO:0061708,Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.,tRNA-5-taurinomethyluridine 2-sulfurtransferase activity,molecular_function
81483,GO:0061709,"The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.",reticulophagy,biological_process
81484,GO:0061710,Catalysis of the reaction: L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.,L-threonylcarbamoyladenylate synthase activity,molecular_function
81485,GO:0061711,Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.,tRNA N(6)-L-threonylcarbamoyladenine synthase activity,molecular_function
81486,GO:0061713,"The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.",anterior neural tube closure,biological_process
81487,GO:0061714,Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.,folic acid receptor activity,molecular_function
81488,GO:0061716,The directed movement of a processed miRNA from the nucleus to the cytoplasm.,miRNA export from nucleus,biological_process
81489,GO:0061718,"The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.",glucose catabolic process to pyruvate,biological_process
81490,GO:0061722,The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.,sulphoglycolysis,biological_process
81491,GO:0061723,The selective degradation of glycogen by macroautophagy.,glycophagy,biological_process
81492,GO:0061724,The selective degradation of lipid droplets by macroautophagy.,lipophagy,biological_process
81493,GO:0061725,The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.,cytosolic lipolysis,biological_process
81494,GO:0061730,"Binding to C-rich, single-stranded, telomere-associated DNA.",C-rich strand telomeric DNA binding,molecular_function
81495,GO:0061731,"Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.",ribonucleoside-diphosphate reductase activity,molecular_function
81496,GO:0061733,Catalysis of the reaction: L-lysyl-[protein] + acetyl-CoA = N6-acetyl-L-lysyl-[protein] + CoA + H+.,protein-lysine-acetyltransferase activity,molecular_function
81497,GO:0061734,"The selective autophagy process in which a mitochondrion is degraded by macroautophagy in a process initiated by mitochondrial depolarization (mtDepo) followed by Parkin binding, and ubiquitination of outer membrane proteins, to remove potentially harm-inducing dysfunctional/damaged mitochondria.",type 2 mitophagy,biological_process
81498,GO:0061736,The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.,engulfment of target by autophagosome,biological_process
81499,GO:0061737,"A G protein-coupled receptor signaling pathway initiated by leukotriene binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",leukotriene signaling pathway,biological_process
81500,GO:0061738,The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.,late endosomal microautophagy,biological_process
81501,GO:0061739,"The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.",protein lipidation involved in autophagosome assembly,biological_process
81502,GO:0061740,The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.,protein targeting to lysosome involved in chaperone-mediated autophagy,biological_process
81503,GO:0061742,A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.,chaperone-mediated autophagy translocation complex,cellular_component
81504,GO:0061743,Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.,motor learning,biological_process
81505,GO:0061744,The specific neuromuscular movement of a single organism in response to external or internal stimuli.,motor behavior,biological_process
81506,GO:0061749,"Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.",forked DNA-dependent helicase activity,molecular_function
81507,GO:0061750,Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment.,acid sphingomyelin phosphodiesterase activity,molecular_function
81508,GO:0061751,Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in a neutral environment.,neutral sphingomyelin phosphodiesterase activity,molecular_function
81509,GO:0061752,Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.,telomeric repeat-containing RNA binding,molecular_function
81510,GO:0061753,The localization process by which an autophagic substrate is delivered to a forming autophagosome.,substrate localization to autophagosome,biological_process
81511,GO:0061754,Any process that reduces the quantity of fibrinogen circulating in the bloodstream.,negative regulation of circulating fibrinogen levels,biological_process
81512,GO:0061755,Any process that increases the quantity of fibrinogen circulating in the bloodstream.,positive regulation of circulating fibrinogen levels,biological_process
81513,GO:0061756,The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.,leukocyte adhesion to vascular endothelial cell,biological_process
81514,GO:0061757,The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.,leukocyte adhesion to arterial endothelial cell,biological_process
81515,GO:0061760,An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.,antifungal innate immune response,biological_process
81516,GO:0061761,Binding to an alpha-latrotoxin receptor.,alpha-latrotoxin receptor binding,molecular_function
81517,GO:0061762,The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.,CAMKK-AMPK signaling cascade,biological_process
81518,GO:0061763,The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.,multivesicular body-lysosome fusion,biological_process
81519,GO:0061764,"The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.",late endosome to lysosome transport via multivesicular body sorting pathway,biological_process
81520,GO:0061766,The process that increases the force with which blood travels through the lungs.,positive regulation of lung blood pressure,biological_process
81521,GO:0061767,The process that decreases the force with which blood travels through the lungs.,negative regulation of lung blood pressure,biological_process
81522,GO:0061768,Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).,magnesium:sodium antiporter activity,molecular_function
81523,GO:0061769,Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H+ + nicotinate mononucleotide.,nicotinate riboside kinase activity,molecular_function
81524,GO:0061770,"Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.",translation elongation factor binding,molecular_function
81525,GO:0061771,"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.",response to caloric restriction,biological_process
81526,GO:0061772,The directed movement of a xenobiotic through the blood-nerve barrier.,xenobiotic transport across blood-nerve barrier,biological_process
81527,GO:0061773,A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.,eNoSc complex,cellular_component
81528,GO:0061775,Facilitating a conformational change to load a cohesin complex around sister chromatids.,cohesin loader activity,molecular_function
81529,GO:0061776,A DNA binding activity in which a protein complex interacts with at least one DNA duplex to encircle the DNA molecules with a loose fitting ring.,ATP-dependent topological DNA co-entrapment activity,molecular_function
81530,GO:0061779,"Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.",Tapasin-ERp57 complex,cellular_component
81531,GO:0061782,Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.,vesicle fusion with vesicle,biological_process
81532,GO:0061783,A catalytic activity that contributes to the degradation of peptidoglycan.,peptidoglycan muralytic activity,molecular_function
81533,GO:0061784,Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.,peptidoglycan N-acetylglucosaminidase activity,molecular_function
81534,GO:0061785,An endopeptidase activity that uses peptidoglycan as a substrate.,peptidoglycan endopeptidase activity,molecular_function
81535,GO:0061786,A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.,peptidoglycan stem peptide endopeptidase activity,molecular_function
81536,GO:0061787,A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge.,peptidoglycan cross-bridge peptide endopeptidase activity,molecular_function
81537,GO:0061788,Binding to Epidermal Growth Factor (EGF) repeats.,EGF repeat binding,molecular_function
81538,GO:0061789,A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.,dense core granule priming,biological_process
81539,GO:0061791,A motor activity driven by GTP hydrolysis.,GTPase motor activity,molecular_function
81540,GO:0061792,Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.,secretory granule maturation,biological_process
81541,GO:0061793,A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.,chromatin lock complex,cellular_component
81542,GO:0061795,"Any process that reduces the pH of the Golgi lumen, corresponding to an increase in hydrogen ion concentration.",Golgi lumen acidification,biological_process
81543,GO:0061796,"A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.",membrane addition at site of mitotic cytokinesis,biological_process
81544,GO:0061797,A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.,pH-gated chloride channel activity,molecular_function
81545,GO:0061798,"Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.","GTP 3',8'-cyclase activity",molecular_function
81546,GO:0061799,"Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.",cyclic pyranopterin monophosphate synthase activity,molecular_function
81547,GO:0061800,A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.,fibronectin fibril,cellular_component
81548,GO:0061801,"A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.",laminin-3B32 trimer,cellular_component
81549,GO:0061802,"The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.",anterior cell cortex,cellular_component
81550,GO:0061803,"The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.",posterior cell cortex,cellular_component
81551,GO:0061804,The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.,mitotic spindle formation (spindle phase one),biological_process
81552,GO:0061805,The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.,mitotic spindle elongation (spindle phase three),biological_process
81553,GO:0061806,"Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.",regulation of DNA recombination at centromere,biological_process
81554,GO:0061807,"Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.",positive regulation of DNA recombination at centromere,biological_process
81555,GO:0061808,"Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.",negative regulation of DNA recombination at centromere,biological_process
81556,GO:0061809,"Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+, in a two step reaction: first an ADP-ribosyl cyclase reaction to synthesise cyclic ADP-ribose, followed by a cyclic ADP-ribose hydrolase reaction to generate (linear) ADP-ribose.","NAD+ nucleosidase activity, cyclic ADP-ribose generating",molecular_function
81557,GO:0061815,Catalysis of the hydrolysis of ubiquitin units from Met1-linked (or linear) polyubiquitin chains.,Met1-linked polyubiquitin deubiquitinase activity,molecular_function
81558,GO:0061816,The selective degradation of proteasomes by macroautophagy.,proteaphagy,biological_process
81559,GO:0061818,The process of assisting in the folding of tRNAs into the correct tertiary structure.,tRNA folding,biological_process
81560,GO:0061819,A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.,telomeric DNA-containing double minutes formation,biological_process
81561,GO:0061820,"A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.",telomeric D-loop disassembly,biological_process
81562,GO:0061821,"Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.",telomeric D-loop binding,molecular_function
81563,GO:0061822,"An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed...",ciliary cap,cellular_component
81564,GO:0061823,"A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum.",ring centriole,cellular_component
81565,GO:0061824,"The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm.",cytosolic ciliogenesis,biological_process
81566,GO:0061825,The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.,podosome core,cellular_component
81567,GO:0061826,"The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.",podosome ring,cellular_component
81568,GO:0061827,The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.,sperm head,cellular_component
81569,GO:0061828,Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.,apical tubulobulbar complex,cellular_component
81570,GO:0061829,Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell.,basal tubulobulbar complex,cellular_component
81571,GO:0061830,"The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.",concave side of sperm head,cellular_component
81572,GO:0061831,Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.,apical ectoplasmic specialization,cellular_component
81573,GO:0061832,Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.,basal ectoplasmic specialization,cellular_component
81574,GO:0061833,"A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction.",protein localization to tricellular tight junction,biological_process
81575,GO:0061834,The part of an actin filament where the structure forks.,actin filament branch point,cellular_component
81576,GO:0061835,The surface of a migrating cell that is in contact with the substratum or cell layer.,ventral surface of cell,cellular_component
81577,GO:0061836,A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions.,intranuclear rod,cellular_component
81578,GO:0061837,Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.,neuropeptide processing,biological_process
81579,GO:0061838,"A histone-variant containing protein complex which forms a centromere specific nucleosome-like structure, involved in centromeric chromatin organization.",CENP-T-W-S-X complex,cellular_component
81580,GO:0061840,Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity ferrous iron transmembrane transporter activity,molecular_function
81581,GO:0061841,"A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.",high-affinity iron exporter complex,cellular_component
81582,GO:0061842,"Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.",microtubule organizing center localization,biological_process
81583,GO:0061843,The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.,Sertoli cell barrier remodeling,biological_process
81584,GO:0061844,An immune response against microbes mediated by anti-microbial peptides in body fluid.,antimicrobial humoral immune response mediated by antimicrobial peptide,biological_process
81585,GO:0061845,The location where a secondary projection arises from a neuron projection.,neuron projection branch point,cellular_component
81586,GO:0061846,The region of the neuronal cytoplasm located in dendritic spines.,dendritic spine cytoplasm,cellular_component
81587,GO:0061847,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.",response to cholecystokinin,biological_process
81588,GO:0061848,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.",cellular response to cholecystokinin,biological_process
81589,GO:0061849,"Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.",telomeric G-quadruplex DNA binding,molecular_function
81590,GO:0061850,That part of the growth cone which represents the distal part of the structure.,growth cone leading edge,cellular_component
81591,GO:0061851,That part of the lamellipodium which represents the distal part of the structure.,leading edge of lamellipodium,cellular_component
81592,GO:0061852,"Cargo receptor complex that recognizes, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles.","retrograde cargo receptor complex, Golgi to ER",cellular_component
81593,GO:0061853,"Any process that modulates the frequency, rate or extent of neuroblast migration.",regulation of neuroblast migration,biological_process
81594,GO:0061854,"Any process that activates or increases the frequency, rate or extent of neuroblast migration.",positive regulation of neuroblast migration,biological_process
81595,GO:0061855,"Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.",negative regulation of neuroblast migration,biological_process
81596,GO:0061856,A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.,Golgi calcium ion transmembrane transport,biological_process
81597,GO:0061857,"The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.",endoplasmic reticulum stress-induced pre-emptive quality control,biological_process
81598,GO:0061860,"Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.",DNA clamp unloader activity,molecular_function
81599,GO:0061862,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.",cellular response to differentiation-inducing factor 2,biological_process
81600,GO:0061863,Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversible depending on the availability of dimers.,microtubule plus end polymerase activity,molecular_function
81601,GO:0061864,"The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell.",basement membrane constituent secretion,biological_process
81602,GO:0061865,The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium.,polarized secretion of basement membrane proteins in epithelium,biological_process
81603,GO:0061867,The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.,establishment of mitotic spindle asymmetry,biological_process
81604,GO:0061868,The orderly movement of a hepatic stellate cell from one site to another.,hepatic stellate cell migration,biological_process
81605,GO:0061869,"Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.",regulation of hepatic stellate cell migration,biological_process
81606,GO:0061870,"Any process that increases the frequency, rate or extent of hepatic stellate cell migration.",positive regulation of hepatic stellate cell migration,biological_process
81607,GO:0061871,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.",negative regulation of hepatic stellate cell migration,biological_process
81608,GO:0061872,The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.,hepatic stellate cell contraction,biological_process
81609,GO:0061873,"Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.",regulation of hepatic stellate cell contraction,biological_process
81610,GO:0061874,"Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.",positive regulation of hepatic stellate cell contraction,biological_process
81611,GO:0061875,"Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction.",negative regulation of hepatic stellate cell contraction,biological_process
81612,GO:0061880,"Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.",regulation of anterograde axonal transport of mitochondrion,biological_process
81613,GO:0061881,"Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.",positive regulation of anterograde axonal transport of mitochondrion,biological_process
81614,GO:0061882,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.",negative regulation of anterograde axonal transport of mitochondrion,biological_process
81615,GO:0061883,A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition.,clathrin-dependent endocytosis involved in vitellogenesis,biological_process
81616,GO:0061884,"Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.",regulation of mini excitatory postsynaptic potential,biological_process
81617,GO:0061885,"Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.",positive regulation of mini excitatory postsynaptic potential,biological_process
81618,GO:0061886,"Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.",negative regulation of mini excitatory postsynaptic potential,biological_process
81619,GO:0061888,"Any process that modulates the frequency, rate or extent of astrocyte activation.",regulation of astrocyte activation,biological_process
81620,GO:0061889,"Any process that decreases the frequency, rate or extent of astrocyte activation.",negative regulation of astrocyte activation,biological_process
81621,GO:0061890,"Any process that increases the frequency, rate or extent of astrocyte activation.",positive regulation of astrocyte activation,biological_process
81622,GO:0061891,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).",calcium ion sensor activity,molecular_function
81623,GO:0061896,"Catalysis of the reaction: all-trans-retinol + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin].","all-trans retinol 3,4-desaturase activity",molecular_function
81624,GO:0061897,"Catalysis of the reaction: all-trans-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].","all-trans retinal 3,4-desaturase activity",molecular_function
81625,GO:0061898,"Catalysis of the reaction: all-trans-retinoic acid + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].","all-trans retinoic acid 3,4-desaturase activity",molecular_function
81626,GO:0061899,"Catalysis of the reaction: 11-cis-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].","11-cis-retinal 3,4-desaturase activity",molecular_function
81627,GO:0061900,"A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.",glial cell activation,biological_process
81628,GO:0061906,"Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.",autophagosome localization,biological_process
81629,GO:0061908,"A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.",phagophore,cellular_component
81630,GO:0061909,"The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.",autophagosome-lysosome fusion,biological_process
81631,GO:0061910,The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.,autophagosome-endosome fusion,biological_process
81632,GO:0061911,"The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome.",amphisome-lysosome fusion,biological_process
81633,GO:0061913,"Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.",positive regulation of growth plate cartilage chondrocyte proliferation,biological_process
81634,GO:0061914,"Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.",negative regulation of growth plate cartilage chondrocyte proliferation,biological_process
81635,GO:0061916,That part of the axonal growth cone which represents the distal part of the structure.,leading edge of axonal growth cone,cellular_component
81636,GO:0061917,That part of the dendritic growth cone which represents the distal part of the structure.,leading edge of dendritic growth cone,cellular_component
81637,GO:0061919,"A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.",process utilizing autophagic mechanism,biological_process
81638,GO:0061920,Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.,protein propionyltransferase activity,molecular_function
81639,GO:0061921,The propionylation of peptidyl-lysine.,peptidyl-lysine propionylation,biological_process
81640,GO:0061922,Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.,histone propionyltransferase activity,molecular_function
81641,GO:0061923,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate.","(2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity",molecular_function
81642,GO:0061924,"Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.",regulation of formation of radial glial scaffolds,biological_process
81643,GO:0061925,"Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.",negative regulation of formation of radial glial scaffolds,biological_process
81644,GO:0061926,"Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds.",positive regulation of formation of radial glial scaffolds,biological_process
81645,GO:0061927,"The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110.",TOC-TIC supercomplex I,cellular_component
81646,GO:0061928,Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.,glutathione specific gamma-glutamylcyclotransferase activity,molecular_function
81647,GO:0061929,Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.,gamma-glutamylaminecyclotransferase activity,molecular_function
81648,GO:0061930,"Any process that modulates the frequency, rate or extent of erythrocyte enucleation.",regulation of erythrocyte enucleation,biological_process
81649,GO:0061931,"Any process that increases the frequency, rate or extent of erythrocyte enucleation.",positive regulation of erythrocyte enucleation,biological_process
81650,GO:0061932,"Any process that decreases the frequency, rate or extent of erythrocyte enucleation.",negative regulation of erythrocyte enucleation,biological_process
81651,GO:0061934,"Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.",regulation of adenine biosynthetic process,biological_process
81652,GO:0061936,"The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.",fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm,biological_process
81653,GO:0061938,A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.,protein localization to somatodendritic compartment,biological_process
81654,GO:0061939,Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.,c-di-GMP signaling,biological_process
81655,GO:0061940,Any process that modulates the rate frequency or extent of c-di-GMP signaling.,regulation of c-di-GMP signaling,biological_process
81656,GO:0061941,"Any process that increases the rate, frequency or extent of c-di-GMP signaling.",positive regulation of c-di-GMP signaling,biological_process
81657,GO:0061942,"Any process that decreases the rate, frequency or extent of c-di-GMP signaling.",negative regulation of c-di-GMP signaling,biological_process
81658,GO:0061944,"Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.",negative regulation of protein K48-linked ubiquitination,biological_process
81659,GO:0061945,"Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.",regulation of protein K48-linked ubiquitination,biological_process
81660,GO:0061948,"The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.",premature acrosome loss,biological_process
81661,GO:0061949,"Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.",regulation of premature acrosome loss,biological_process
81662,GO:0061950,"Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.",negative regulation of premature acrosome loss,biological_process
81663,GO:0061951,The directed movement of a protein to a specific location in a plasma membrane.,establishment of protein localization to plasma membrane,biological_process
81664,GO:0061952,"The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.",midbody abscission,biological_process
81665,GO:0061953,Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.,mRNA (adenine-N1-)-methyltransferase activity,molecular_function
81666,GO:0061956,"The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.",penetration of cumulus oophorus,biological_process
81667,GO:0061957,"A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1.",NVT complex,cellular_component
81668,GO:0061959,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.",response to (R)-carnitine,biological_process
81669,GO:0061963,"Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",regulation of entry into reproductive diapause,biological_process
81670,GO:0061964,"Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",negative regulation of entry into reproductive diapause,biological_process
81671,GO:0061965,"Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",positive regulation of entry into reproductive diapause,biological_process
81672,GO:0061966,The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.,establishment of left/right asymmetry,biological_process
81673,GO:0061967,The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.,establishment of left sidedness,biological_process
81674,GO:0061968,The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.,maintenance of left/right asymmetry,biological_process
81675,GO:0061969,The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.,maintenance of left sidedness,biological_process
81676,GO:0061970,The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.,maintenance of right sidedness,biological_process
81677,GO:0061971,The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.,replacement bone morphogenesis,biological_process
81678,GO:0061972,The process in which bone which forms superficially in the organism are generated and organized.,dermal bone morphogenesis,biological_process
81679,GO:0061973,The process in which bone which forms deep in the organism are generated and organized.,membrane bone morphogenesis,biological_process
81680,GO:0061974,The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.,perichondral bone morphogenesis,biological_process
81681,GO:0061975,"The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.",articular cartilage development,biological_process
81682,GO:0061976,"The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.",temporomandibular joint articular cartilage development,biological_process
81683,GO:0061977,"The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.",hip joint articular cartilage development,biological_process
81684,GO:0061978,"The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.",mandibular condyle articular cartilage development,biological_process
81685,GO:0061979,"The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.",femoral head articular cartilage development,biological_process
81686,GO:0061980,"Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.",regulatory RNA binding,molecular_function
81687,GO:0061982,A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.,meiosis I cell cycle process,biological_process
81688,GO:0061983,A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.,meiosis II cell cycle process,biological_process
81689,GO:0061984,"A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.",catabolite repression,biological_process
81690,GO:0061985,"A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.",carbon catabolite repression,biological_process
81691,GO:0061986,"Any process involving glucose that decreases the frequency, rate or extent or transcription.",negative regulation of transcription by glucose,biological_process
81692,GO:0061987,"Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.",negative regulation of transcription from RNA polymerase II promoter by glucose,biological_process
81693,GO:0061988,The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.,karyosome formation,biological_process
81694,GO:0061989,The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.,sperm karyosome formation,biological_process
81695,GO:0061990,Catalysis of the reaction: octanoyl-CoA + H+ + malonyl-[ACP] = 3-oxodecanoyl-[ACP] + CO2 + CoA.,beta-ketodecanoyl-[acyl-carrier-protein] synthase activity,molecular_function
81696,GO:0061993,A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).,calcium:proton antiporter complex,cellular_component
81697,GO:0061995,"An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.",ATP-dependent protein-DNA complex displacement activity,molecular_function
81698,GO:0061999,"Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.",regulation of cardiac endothelial to mesenchymal transition,biological_process
81699,GO:0062000,"Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.",positive regulation of cardiac endothelial to mesenchymal transition,biological_process
81700,GO:0062001,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.",negative regulation of cardiac endothelial to mesenchymal transition,biological_process
81701,GO:0062003,"Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.","negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity",biological_process
81702,GO:0062009,"The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.",secondary palate development,biological_process
81703,GO:0062010,The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.,primitive palate development,biological_process
81704,GO:0062011,A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.,mitochondrial respiratory chain complex IV pre-assembly complex,cellular_component
81705,GO:0062012,"Any process that modulates the rate, frequency or extent of a small molecule metabolic process.",regulation of small molecule metabolic process,biological_process
81706,GO:0062013,"Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.",positive regulation of small molecule metabolic process,biological_process
81707,GO:0062014,"Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.",negative regulation of small molecule metabolic process,biological_process
81708,GO:0062025,"Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.",regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,biological_process
81709,GO:0062026,"Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.",negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process,biological_process
81710,GO:0062027,"Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.",positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process,biological_process
81711,GO:0062028,"Any process that modulates the rate, frequency or extent of cytoplasmic stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic stress granule.",regulation of cytoplasmic stress granule assembly,biological_process
81712,GO:0062029,"Any process that starts or increases the rate, frequency or extent of cytoplasmic stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic stress granule.",positive regulation of cytoplasmic stress granule assembly,biological_process
81713,GO:0062030,"Any process that stops or decreases the rate, frequency or extent of cytoplasmic stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic stress granule.",negative regulation of cytoplasmic stress granule assembly,biological_process
81714,GO:0062031,"A MAPK cascade containing at least the Kss1 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Kss1. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The filamentous growth MAPK cascade is activated as a result of partial nutrient deprivation and  results in filamentous growth.",filamentous growth MAPK cascade,biological_process
81715,GO:0062032,"The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.",cichorine biosynthetic process,biological_process
81716,GO:0062033,"Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.",positive regulation of mitotic sister chromatid segregation,biological_process
81717,GO:0062034,"The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.",L-pipecolic acid biosynthetic process,biological_process
81718,GO:0062035,"The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.",sensory perception of cold stimulus,biological_process
81719,GO:0062036,"The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.",sensory perception of hot stimulus,biological_process
81720,GO:0062037,"Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.",D-loop DNA binding,molecular_function
81721,GO:0062038,"Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.",positive regulation of pheromone response MAPK cascade,biological_process
81722,GO:0062039,"A type of extracellular matrix that surrounds the cells within a microbial biofilm. The matrix is composed of extracellular polymeric substances including exopolysaccharides, proteins, nucleic acids, lipids, and other biomolecules.",biofilm matrix,cellular_component
81723,GO:0062040,"An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.",fungal biofilm matrix,cellular_component
81724,GO:0062041,"Any process that increases the rate or extent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.",positive regulation of meiotic sister chromatid arm separation,biological_process
81725,GO:0062042,"Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",regulation of cardiac epithelial to mesenchymal transition,biological_process
81726,GO:0062043,"Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",positive regulation of cardiac epithelial to mesenchymal transition,biological_process
81727,GO:0062044,"Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",negative regulation of cardiac epithelial to mesenchymal transition,biological_process
81728,GO:0062045,Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.,L-lysine:pyruvate alpha-transaminase activity,molecular_function
81729,GO:0062046,Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.,dehydropipecolic acid reductase activity,molecular_function
81730,GO:0062047,Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.,pipecolic acid N-hydroxylase activity,molecular_function
81731,GO:0062048,A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.,lymphotoxin complex,cellular_component
81732,GO:0062049,A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.,protein phosphatase inhibitor complex,cellular_component
81733,GO:0062050,A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.,GPI-mannose ethanolamine phosphate phosphodiesterase activity,molecular_function
81734,GO:0062051,A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.,lipopolysaccharide transport system,cellular_component
81735,GO:0062052,The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.,starch granule initiation,biological_process
81736,GO:0062054,Enables the energy-independent facilitated diffusion of a fluoride ion through a transmembrane aqueous pore or channel.,fluoride channel activity,molecular_function
81737,GO:0062055,A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.,photosynthetic state transition,biological_process
81738,GO:0062056,"The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.",compound eye pigment cell differentiation,biological_process
81739,GO:0062057,Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).,L-aspartate:fumarate antiporter activity,molecular_function
81740,GO:0062058,Binding to a transcription factor TFIIH holo complex.,transcription factor TFIIH holo complex binding,molecular_function
81741,GO:0062059,Binding to a FACT complex.,FACT complex binding,molecular_function
81742,GO:0062060,Binding to a NuA4 histone acetyltransferase complex.,NuA4 histone acetyltransferase complex binding,molecular_function
81743,GO:0062061,Binding to a TAP complex.,TAP complex binding,molecular_function
81744,GO:0062062,Binding to an oligosaccharyltransferase complex.,oligosaccharyltransferase complex binding,molecular_function
81745,GO:0062063,Binding to a BBSome complex.,BBSome binding,molecular_function
81746,GO:0062064,Binding to a box C/D methylation guide snoRNP complex.,box C/D methylation guide snoRNP complex binding,molecular_function
81747,GO:0062065,Binding to a box H/ACA snoRNP complex.,box H/ACA snoRNP complex binding,molecular_function
81748,GO:0062066,Binding to a PSII associated light-harvesting complex II.,PSII associated light-harvesting complex II binding,molecular_function
81749,GO:0062067,Binding to a chloroplast photosystem I.,chloroplast photosystem I binding,molecular_function
81750,GO:0062068,Binding to a chloroplast photosystem II.,chloroplast photosystem II binding,molecular_function
81751,GO:0062069,Binding to a GARP complex.,GARP complex binding,molecular_function
81752,GO:0062070,Binding to a SAGA complex.,SAGA complex binding,molecular_function
81753,GO:0062071,A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.,Pi Mi complex,cellular_component
81754,GO:0062072,"A histone reader that recognizes a histone H3 trimethylated at lysine 9. In some organisms, there is only H3K9me2, not H3K9me3, but this modification is recognized by homologous readers.",histone H3K9me2/3 reader activity,molecular_function
81755,GO:0062073,A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export.,histone mRNA stem-loop binding complex,cellular_component
81756,GO:0062074,"An area where exine is reduced or absent, in the pollen wall.",pollen aperture,cellular_component
81757,GO:0062075,"The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.",pollen aperture formation,biological_process
81758,GO:0062076,"Catalysis of the reaction: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA) and add a fourth double bond (a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA).",acyl-CoA (8-3)-desaturase activity,molecular_function
81759,GO:0062077,"A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.","phenylacetyl-CoA 1,2-epoxidase complex",cellular_component
81760,GO:0062078,Binding to a TSC1-TSC2 complex.,TSC1-TSC2 complex binding,molecular_function
81761,GO:0062079,"A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or...",ATG2-ATG18 complex,cellular_component
81762,GO:0062080,Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.,inhibitory MHC class Ib receptor activity,molecular_function
81763,GO:0062081,Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.,activating MHC class Ib receptor activity,molecular_function
81764,GO:0062082,Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.,HLA-E specific inhibitory MHC class Ib receptor activity,molecular_function
81765,GO:0062083,Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.,HLA-G specific inhibitory MHC class Ib receptor activity,molecular_function
81766,GO:0062084,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.",regulation of capsule polysaccharide biosynthetic process,biological_process
81767,GO:0062085,"Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.",positive regulation of capsule polysaccharide biosynthetic process,biological_process
81768,GO:0062086,"Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.",regulation of vein smooth muscle contraction,biological_process
81769,GO:0062087,"Any process that increases the frequency, rate or extent of vein smooth muscle contraction.",positive regulation of vein smooth muscle contraction,biological_process
81770,GO:0062088,"Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.",negative regulation of vein smooth muscle contraction,biological_process
81771,GO:0062089,"Any process that modulates the rate, frequency or extent of taurine biosynthesis.",regulation of taurine biosynthetic process,biological_process
81772,GO:0062090,"Any process that activates or increases the frequency, rate or extent of taurine biosynthesis.",positive regulation of taurine biosynthetic process,biological_process
81773,GO:0062091,A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.,Ycf2/FtsHi complex,cellular_component
81774,GO:0062092,"A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.",Yae1-Lto1 complex,cellular_component
81775,GO:0062093,The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.,lysophagy,biological_process
81776,GO:0062094,"The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.",stomach development,biological_process
81777,GO:0062096,The disaggregation of a kinetochore into its constituent components.,kinetochore disassembly,biological_process
81778,GO:0062097,The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.,chemosynthesis,biological_process
81779,GO:0062098,"Any process that modulates the frequency, rate or extent of programmed necrotic cell death.",regulation of programmed necrotic cell death,biological_process
81780,GO:0062099,"Any process that decreases the frequency, rate or extent of programmed necrotic cell death.",negative regulation of programmed necrotic cell death,biological_process
81781,GO:0062100,"Any process that increases the frequency, rate or extent of programmed necrotic cell death.",positive regulation of programmed necrotic cell death,biological_process
81782,GO:0062101,Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.,peptidyl-aspartic acid 3-dioxygenase activity,molecular_function
81783,GO:0062102,Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.,female germline stem cell symmetric division,biological_process
81784,GO:0062104,Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.,pumilio-response element binding,molecular_function
81785,GO:0062105,Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.,RNA 2'-O-methyltransferase activity,molecular_function
81786,GO:0062107,"Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.",regulation of protein localization to non-growing cell tip,biological_process
81787,GO:0062108,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.",negative regulation of protein localization to non-growing cell tip,biological_process
81788,GO:0062109,"Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.",regulation of DNA recombinase disassembly,biological_process
81789,GO:0062110,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.",negative regulation of DNA recombinase disassembly,biological_process
81790,GO:0062111,"The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.",zinc ion import into organelle,biological_process
81791,GO:0062112,The chemical reactions and pathways resulting in the formation of a fatty acid primary amide.,fatty acid primary amide biosynthetic process,biological_process
81792,GO:0062113,The volume enclosed by the membrane of an early phagosome.,early phagosome lumen,cellular_component
81793,GO:0062116,A chloroplast-derived plastid in which the solid form of phenol is stored.,phenyloplast,cellular_component
81794,GO:0062119,"A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.",LinE complex,cellular_component
81795,GO:0062120,"The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.",LinE complex assembly,biological_process
81796,GO:0062121,The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.,linear element maturation,biological_process
81797,GO:0062122,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group to the lysine residue at position 37 of the histone H3 protein.,histone H3K37 methyltransferase activity,molecular_function
81798,GO:0062123,"Any process that modulates the rate, frequency or extent of linear element maturation.",regulation of linear element maturation,biological_process
81799,GO:0062124,Combining with 4-hydroxybutyrte to initiate a change in cell activity.,4-hydroxybutyrate receptor activity,molecular_function
81800,GO:0062125,"Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).",regulation of mitochondrial gene expression,biological_process
81801,GO:0062126,"The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.",fatty acid primary amide metabolic process,biological_process
81802,GO:0062127,The chemical reactions and pathways resulting in the breakdown of primary fatty amides.,fatty acid primary amide catabolic process,biological_process
81803,GO:0062128,"A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.",MutSgamma complex,cellular_component
81804,GO:0062129,"Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.",chitin-based extracellular matrix,cellular_component
81805,GO:0062131,Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = progoitrin + an oxidized electron acceptor + H2O.,3-butenylglucosinolate 2-hydroxylase activity,molecular_function
81806,GO:0062132,"Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.",regulation of L-glutamine biosynthetic process,biological_process
81807,GO:0062133,"Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.",negative regulation of L-glutamine biosynthetic process,biological_process
81808,GO:0062134,"Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis.",positive regulation of L-glutamine biosynthetic process,biological_process
81809,GO:0062136,A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.,low-density lipoprotein receptor complex,cellular_component
81810,GO:0062137,Any protein complex that is part of a membrane and which functions as a cargo receptor.,cargo receptor complex,cellular_component
81811,GO:0062139,"The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.",camera-type eye photoreceptor cell development,biological_process
81812,GO:0062140,A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.,hyphae septin collar,cellular_component
81813,GO:0062141,A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.,nuclear exosome targeting complex,cellular_component
81814,GO:0062142,The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.,L-beta-ethynylserine biosynthetic process,biological_process
81815,GO:0062143,The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.,L-propargylglycine biosynthetic process,biological_process
81816,GO:0062144,Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H+ + L-propargylglycine.,L-propargylglycine synthase activity,molecular_function
81817,GO:0062145,Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate.,L-propargylglycine--L-glutamate ligase activity,molecular_function
81818,GO:0062146,Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4+.,4-chloro-allylglycine synthase activity,molecular_function
81819,GO:0062147,Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.,L-lysine 4-chlorinase activity,molecular_function
81820,GO:0062148,Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.,L-gamma-glutamyl-L-propargylglycine hydroxylase activity,molecular_function
81821,GO:0062150,"Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].","amorpha-4,11-diene 12-monooxygenase activity",molecular_function
81822,GO:0062151,A protein-containing complex that is capable of catalase activity.,catalase complex,cellular_component
81823,GO:0062152,Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.,mRNA (cytidine-5-)-methyltransferase activity,molecular_function
81824,GO:0062153,A protein adaptor that recognizes and binds an RNA molecule modified by C5-methylcytidine.,C5-methylcytidine-containing RNA reader activity,molecular_function
81825,GO:0062154,Catalysis of the reaction: H+ + H2O + N6-methyl-AMP = IMP + methylamine. Can also use N6-methyl-dAMP as a substrate.,N6-methyl-AMP deaminase activity,molecular_function
81826,GO:0062155,A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms.,curli secretion complex,cellular_component
81827,GO:0062156,Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.,mitochondrial ATP-gated potassium channel activity,molecular_function
81828,GO:0062157,A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.,mitochondrial ATP-gated potassium channel complex,cellular_component
81829,GO:0062158,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).,chloride:proton antiporter activity,molecular_function
81830,GO:0062159,"A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.",contractile vacuole complex,cellular_component
81831,GO:0062160,A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.,spongiome,cellular_component
81832,GO:0062161,"Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.",regulation of pyocyanine biosynthetic process,biological_process
81833,GO:0062162,"Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.",positive regulation of pyocyanine biosynthetic process,biological_process
81834,GO:0062163,"The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.",pseudohyphal septin ring assembly,biological_process
81835,GO:0062164,"Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.",regulation of pseudohyphal septin ring assembly,biological_process
81836,GO:0062165,"Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.",positive regulation of pseudohyphal septin ring assembly,biological_process
81837,GO:0062166,"Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly.",negative regulation of pseudohyphal septin ring assembly,biological_process
81838,GO:0062167,"A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.",complement component C1q complex,cellular_component
81839,GO:0062168,"Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.",negative regulation of plus-end directed microtubule sliding,biological_process
81840,GO:0062169,"Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.",regulation of plus-end directed microtubule sliding,biological_process
81841,GO:0062171,The chemical reactions and pathways resulting in the formation of lutein.,lutein biosynthetic process,biological_process
81842,GO:0062172,The chemical reactions and pathways resulting in the breakdown of lutein.,lutein catabolic process,biological_process
81843,GO:0062173,The chemical reactions and pathways by which living organisms transform brexanolone.,brexanolone metabolic process,biological_process
81844,GO:0062174,The chemical reactions and pathways resulting in the formation of brexanolone.,brexanolone biosynthetic process,biological_process
81845,GO:0062175,The chemical reactions and pathways resulting in the breakdown of brexanolone.,brexanolone catabolic process,biological_process
81846,GO:0062176,A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.,R-loop processing,biological_process
81847,GO:0062177,"The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.",radial spoke assembly,biological_process
81848,GO:0062179,Catalysis of the hydroxylation of C-23 of any form of vitamin D.,vitamin D 23-hydroxylase activity,molecular_function
81849,GO:0062180,"Catalysis of the reaction: calcidiol + 2 H+ + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].",25-hydroxycholecalciferol-23-hydroxylase activity,molecular_function
81850,GO:0062181,"Catatlysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].","1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity",molecular_function
81851,GO:0062182,Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,all-trans retinoic acid 4-hydrolase activity,molecular_function
81852,GO:0062183,Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,all-trans retinoic acid 18-hydroxylase activity,molecular_function
81853,GO:0062184,"Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].",testosterone 16-beta-hydroxylase activity,molecular_function
81854,GO:0062185,Catalysis of the reaction:2 H+ + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].,secalciferol 1-monooxygenase activity,molecular_function
81855,GO:0062186,Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.,anandamide epoxidase activity,molecular_function
81856,GO:0062187,"Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].","anandamide 8,9 epoxidase activity",molecular_function
81857,GO:0062188,"Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].","anandamide 11,12 epoxidase activity",molecular_function
81858,GO:0062189,"Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].","anandamide 14,15 epoxidase activity",molecular_function
81859,GO:0062191,The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.,galactoxylomannan biosynthetic process,biological_process
81860,GO:0062192,Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.,L-rhamnose mutarotase activity,molecular_function
81861,GO:0062193,"Catalysis of the reactions: beta-D-ribopyranose = beta-D-ribofuranose, and beta-allofuranose = beta-allopyranose.",D-ribose pyranase activity,molecular_function
81862,GO:0062194,A microtubule minus end that is part of a cytoplasmic microtubule.,cytoplasmic microtubule minus-end,cellular_component
81863,GO:0062195,The organization process that preserves a microtubule bundle in a stable functional or structural state.,microtubule bundle maintenance,biological_process
81864,GO:0062196,Any process that modulates the size of a lysosome.,regulation of lysosome size,biological_process
81865,GO:0062197,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.",cellular response to chemical stress,biological_process
81866,GO:0062200,"An intracellular signaling cascade that starts with the activation of S. cerevisiae Kic1p, which activate Mob2p and Cbk1p. Cbk1p phosphorylates Ace2p, which results in its nuclear translocation, where it regulates transcription of genes involved in polarity and morphogenesis.",RAM/MOR signaling,biological_process
81867,GO:0062201,"A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.",actin wave,cellular_component
81868,GO:0062202,"Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.","Labd-13(16),14-diene-9-ol synthase activity",molecular_function
81869,GO:0062203,Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.,Viteagnusin D synthase activity,molecular_function
81870,GO:0062204,Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.,(13S)-vitexifolin A synthase activity,molecular_function
81871,GO:0062205,Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene.,miltiradiene synthase activity,molecular_function
81872,GO:0062206,Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.,manoyl oxide synthase activity,molecular_function
81873,GO:0062207,"Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.",regulation of pattern recognition receptor signaling pathway,biological_process
81874,GO:0062208,"Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.",positive regulation of pattern recognition receptor signaling pathway,biological_process
81875,GO:0062209,Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.,spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination,biological_process
81876,GO:0062210,The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.,shoot regeneration,biological_process
81877,GO:0062211,The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.,root regeneration,biological_process
81878,GO:0062212,"Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.",regulation of mitotic DNA replication initiation from early origin,biological_process
81879,GO:0062213,Catalysis of the reaction: peroxynitrite = nitrate.,peroxynitrite isomerase activity,molecular_function
81880,GO:0062223,"Any process that regulates the rate, frequency or extent of somatic muscle development.",regulation of somatic muscle development,biological_process
81881,GO:0062224,"Any process that increases the rate, frequency or extent of somatic muscle development.",positive regulation of somatic muscle development,biological_process
81882,GO:0062225,"Any process that decreases the rate, frequency or extent of somatic muscle development.",negative regulation of somatic muscle development,biological_process
81883,GO:0062226,"Any process that modulates the rate, frequency or extent of adult somatic muscle development.",regulation of adult somatic muscle development,biological_process
81884,GO:0062227,"Any process that increases the rate, frequency or extent of adult somatic muscle development.",positive regulation of adult somatic muscle development,biological_process
81885,GO:0062228,"Any process that decreases the rate, frequency or extent of adult somatic muscle development.",negative regulation of adult somatic muscle development,biological_process
81886,GO:0062229,"Any process that modulates the rate, frequency or extent of larval somatic muscle development.",regulation of larval somatic muscle development,biological_process
81887,GO:0062230,"Any process that decreases the rate, frequency or extent of larval somatic muscle development.",negative regulation of larval somatic muscle development,biological_process
81888,GO:0062231,"Any process that increases the rate, frequency or extent of larval somatic muscle development.",positive regulation of larval somatic muscle development,biological_process
81889,GO:0062232,The chemical reactions and pathways resulting in the breakdown of prostanoids.,prostanoid catabolic process,biological_process
81890,GO:0062233,The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.,F2-isoprostane catabolic process,biological_process
81891,GO:0062234,"The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.",platelet activating factor catabolic process,biological_process
81892,GO:0062235,"The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.",axonemal basal plate assembly,biological_process
81893,GO:0062236,The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.,ionocyte differentiation,biological_process
81894,GO:0062237,"Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.",protein localization to postsynapse,biological_process
81895,GO:0062238,A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.,Smp focus,cellular_component
81896,GO:0062239,"Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.",heterochromatin-nuclear membrane anchor activity,molecular_function
81897,GO:0062240,"Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.",euchromatin-nuclear membrane anchor activity,molecular_function
81898,GO:0062241,"Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.",double strand break-nuclear membrane anchor activity,molecular_function
81899,GO:0062242,One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.,double membrane vesicle viral factory membrane,cellular_component
81900,GO:0062243,The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.,double membrane vesicle viral factory outer membrane,cellular_component
81901,GO:0062244,The volume surrounded by the inner membrane of a double membrane vesicle viral factory.,double membrane vesicle viral factory lumen,cellular_component
81902,GO:0062245,The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.,double membrane vesicle viral factory inner membrane,cellular_component
81903,GO:0062246,The volume enclosed by an exocytic vesicle.,exocytic vesicle lumen,cellular_component
81904,GO:0062247,A intracellular vesicle that is part of a chloroplast.,chloroplast vesicle,cellular_component
81905,GO:0062248,"The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.",cleistothecium formation,biological_process
81906,GO:0065001,The pattern specification process in which the polarity of a body or organ axis is established and maintained.,specification of axis polarity,biological_process
81907,GO:0065002,"The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.",intracellular protein transmembrane transport,biological_process
81908,GO:0065003,"The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.",protein-containing complex assembly,biological_process
81909,GO:0065004,"The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.",protein-DNA complex assembly,biological_process
81910,GO:0065005,"The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.",protein-lipid complex assembly,biological_process
81911,GO:0065007,"Any process that modulates a measurable attribute of any biological process, quality or function.",biological regulation,biological_process
81912,GO:0065008,"Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.",regulation of biological quality,biological_process
81913,GO:0065009,"Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.",regulation of molecular function,biological_process
81914,GO:0065010,"Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.",extracellular membrane-bounded organelle,cellular_component
81915,GO:0070001,Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.,aspartic-type peptidase activity,molecular_function
81916,GO:0070002,Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.,glutamic-type peptidase activity,molecular_function
81917,GO:0070003,Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.,threonine-type peptidase activity,molecular_function
81918,GO:0070004,Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.,cysteine-type exopeptidase activity,molecular_function
81919,GO:0070005,Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.,cysteine-type aminopeptidase activity,molecular_function
81920,GO:0070006,"Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metalloaminopeptidase activity,molecular_function
81921,GO:0070007,Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.,glutamic-type endopeptidase activity,molecular_function
81922,GO:0070008,Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).,serine-type exopeptidase activity,molecular_function
81923,GO:0070009,Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).,serine-type aminopeptidase activity,molecular_function
81924,GO:0070012,"Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.",oligopeptidase activity,molecular_function
81925,GO:0070013,An organelle lumen that is part of an intracellular organelle.,intracellular organelle lumen,cellular_component
81926,GO:0070014,"A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.",sucrase-isomaltase complex,cellular_component
81927,GO:0070016,"Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signaling and cytoskeletal regulation.",armadillo repeat domain binding,molecular_function
81928,GO:0070017,A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.,alphav-beta3 integrin-thrombospondin complex,cellular_component
81929,GO:0070021,"A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.",transforming growth factor beta ligand-receptor complex,cellular_component
81930,GO:0070023,A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.,interleukin-12-interleukin-12 receptor complex,cellular_component
81931,GO:0070024,"A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).",CD19-Vav-PIK3R1 complex,cellular_component
81932,GO:0070025,Binding to carbon monoxide (CO).,carbon monoxide binding,molecular_function
81933,GO:0070026,Binding to nitric oxide (NO).,nitric oxide binding,molecular_function
81934,GO:0070027,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).",carbon monoxide sensor activity,molecular_function
81935,GO:0070029,A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.,alphav-beta3 integrin-osteopontin complex,cellular_component
81936,GO:0070030,A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.,alphav-beta1 integrin-osteopontin complex,cellular_component
81937,GO:0070031,A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.,alphav-beta5 integrin-osteopontin complex,cellular_component
81938,GO:0070032,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex,cellular_component
81939,GO:0070033,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex,cellular_component
81940,GO:0070034,Binding to the telomerase RNA template.,telomerase RNA binding,molecular_function
81941,GO:0070037,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.,rRNA (pseudouridine) methyltransferase activity,molecular_function
81942,GO:0070038,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.,rRNA (pseudouridine-N3-)-methyltransferase activity,molecular_function
81943,GO:0070039,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.,rRNA (guanosine-2'-O-ribose)-methyltransferase activity,molecular_function
81944,GO:0070040,Catalysis of the reaction: adenosine2503 in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine2503 in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.,rRNA (adenine(2503)-C2-)-methyltransferase activity,molecular_function
81945,GO:0070041,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.,rRNA (uridine-C5-)-methyltransferase activity,molecular_function
81946,GO:0070042,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.,rRNA (uridine-N3-)-methyltransferase activity,molecular_function
81947,GO:0070043,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.,rRNA (guanine-N7-)-methyltransferase activity,molecular_function
81948,GO:0070044,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-1a complex,cellular_component
81949,GO:0070045,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-2 complex,cellular_component
81950,GO:0070046,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-3 complex,cellular_component
81951,GO:0070047,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-4 complex,cellular_component
81952,GO:0070048,"A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).",endobrevin-SNAP-25-syntaxin-1a complex,cellular_component
81953,GO:0070049,"A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).",endobrevin-SNAP-25-syntaxin-2 complex,cellular_component
81954,GO:0070050,"The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.",neuron cellular homeostasis,biological_process
81955,GO:0070051,"Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.",fibrinogen binding,molecular_function
81956,GO:0070052,Binding to a type V collagen trimer.,collagen V binding,molecular_function
81957,GO:0070053,Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.,thrombospondin receptor activity,molecular_function
81958,GO:0070054,"Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.","mRNA splicing, via endonucleolytic cleavage and ligation",biological_process
81959,GO:0070056,The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.,prospore membrane leading edge,cellular_component
81960,GO:0070057,The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.,prospore membrane spindle pole body attachment site,cellular_component
81961,GO:0070058,"The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.",tRNA gene clustering,biological_process
81962,GO:0070059,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.",intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,biological_process
81963,GO:0070060,The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.,'de novo' actin filament nucleation,biological_process
81964,GO:0070061,"Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.",fructose binding,molecular_function
81965,GO:0070062,"A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",extracellular exosome,cellular_component
81966,GO:0070063,Binding to an RNA polymerase molecule or complex.,RNA polymerase binding,molecular_function
81967,GO:0070064,"Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.",proline-rich region binding,molecular_function
81968,GO:0070065,"A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).",cellubrevin-VAMP4-syntaxin-16 complex,cellular_component
81969,GO:0070066,"A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).",cellubrevin-VAMP4-endobrevin-syntaxin-6 complex,cellular_component
81970,GO:0070067,"A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).",syntaxin-6-syntaxin-16-Vti1a complex,cellular_component
81971,GO:0070068,"A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).",VAMP4-syntaxin-6-syntaxin-16-Vti1a complex,cellular_component
81972,GO:0070069,"A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.",cytochrome complex,cellular_component
81973,GO:0070070,"The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.",proton-transporting V-type ATPase complex assembly,biological_process
81974,GO:0070071,"The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.",proton-transporting two-sector ATPase complex assembly,biological_process
81975,GO:0070072,"The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.",vacuolar proton-transporting V-type ATPase complex assembly,biological_process
81976,GO:0070073,The process in which voltage-gated calcium channels become localized together in high densities.,clustering of voltage-gated calcium channels,biological_process
81977,GO:0070074,"A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.",mononeme,cellular_component
81978,GO:0070075,"The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.",tear secretion,biological_process
81979,GO:0070080,"Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.",titin Z domain binding,molecular_function
81980,GO:0070081,A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.,clathrin-sculpted monoamine transport vesicle,cellular_component
81981,GO:0070082,The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.,clathrin-sculpted monoamine transport vesicle lumen,cellular_component
81982,GO:0070083,The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.,clathrin-sculpted monoamine transport vesicle membrane,cellular_component
81983,GO:0070086,"Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.",ubiquitin-dependent endocytosis,biological_process
81984,GO:0070087,"Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.",chromo shadow domain binding,molecular_function
81985,GO:0070088,"An inclusion body located in the cytoplasm of prokaryotes that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.",polyhydroxyalkanoate granule,cellular_component
81986,GO:0070089,Enables the transmembrane transfer of a potassium cation by a channel that opens when a chloride ion has been bound by the channel complex or one of its constituent parts.,chloride-activated potassium channel activity,molecular_function
81987,GO:0070090,"The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.",metaphase plate,cellular_component
81988,GO:0070091,The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).,glucagon secretion,biological_process
81989,GO:0070092,"Any process that modulates the frequency, rate or extent of the regulated release of glucagon.",regulation of glucagon secretion,biological_process
81990,GO:0070093,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.",negative regulation of glucagon secretion,biological_process
81991,GO:0070094,"Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.",positive regulation of glucagon secretion,biological_process
81992,GO:0070095,Binding to fructose 6-phosphate.,fructose-6-phosphate binding,molecular_function
81993,GO:0070096,"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.",mitochondrial outer membrane translocase complex assembly,biological_process
81994,GO:0070097,Binding to the delta subunit of the catenin complex.,delta-catenin binding,molecular_function
81995,GO:0070098,"The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",chemokine-mediated signaling pathway,biological_process
81996,GO:0070099,"Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway.",regulation of chemokine-mediated signaling pathway,biological_process
81997,GO:0070100,"Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway.",negative regulation of chemokine-mediated signaling pathway,biological_process
81998,GO:0070101,"Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway.",positive regulation of chemokine-mediated signaling pathway,biological_process
81999,GO:0070102,"The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-6-mediated signaling pathway,biological_process
82000,GO:0070103,"Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway.",regulation of interleukin-6-mediated signaling pathway,biological_process
82001,GO:0070104,"Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.",negative regulation of interleukin-6-mediated signaling pathway,biological_process
82002,GO:0070105,"Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.",positive regulation of interleukin-6-mediated signaling pathway,biological_process
82003,GO:0070106,"The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-27-mediated signaling pathway,biological_process
82004,GO:0070107,"Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway.",regulation of interleukin-27-mediated signaling pathway,biological_process
82005,GO:0070108,"Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.",negative regulation of interleukin-27-mediated signaling pathway,biological_process
82006,GO:0070109,"Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.",positive regulation of interleukin-27-mediated signaling pathway,biological_process
82007,GO:0070110,A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.,ciliary neurotrophic factor receptor complex,cellular_component
82008,GO:0070111,"A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.",organellar chromatophore,cellular_component
82009,GO:0070112,Either of the lipid bilayers that surround an organellar chromatophore.,organellar chromatophore membrane,cellular_component
82010,GO:0070113,"The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.",organellar chromatophore inner membrane,cellular_component
82011,GO:0070114,"The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.",organellar chromatophore outer membrane,cellular_component
82012,GO:0070115,The region between the inner and outer lipid bilayers that surround an organellar chromatophore.,organellar chromatophore intermembrane space,cellular_component
82013,GO:0070116,A thylakoid located in an organellar chromatophore.,organellar chromatophore thylakoid,cellular_component
82014,GO:0070117,The volume enclosed by an organellar chromatophore thylakoid membrane.,organellar chromatophore thylakoid lumen,cellular_component
82015,GO:0070118,The lipid bilayer membrane of any thylakoid within an organellar chromatophore.,organellar chromatophore thylakoid membrane,cellular_component
82016,GO:0070119,Binding to the cytokine ciliary neurotrophic factor.,ciliary neurotrophic factor binding,molecular_function
82017,GO:0070120,"The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",ciliary neurotrophic factor-mediated signaling pathway,biological_process
82018,GO:0070121,"The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.",Kupffer's vesicle development,biological_process
82019,GO:0070123,Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.,"transforming growth factor beta receptor activity, type III",molecular_function
82020,GO:0070124,"The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.",mitochondrial translational initiation,biological_process
82021,GO:0070125,The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.,mitochondrial translational elongation,biological_process
82022,GO:0070126,"The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).",mitochondrial translational termination,biological_process
82023,GO:0070127,"The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.",tRNA aminoacylation for mitochondrial protein translation,biological_process
82024,GO:0070129,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.",regulation of mitochondrial translation,biological_process
82025,GO:0070130,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.",negative regulation of mitochondrial translation,biological_process
82026,GO:0070131,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.",positive regulation of mitochondrial translation,biological_process
82027,GO:0070132,"Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.",regulation of mitochondrial translational initiation,biological_process
82028,GO:0070133,"Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.",negative regulation of mitochondrial translational initiation,biological_process
82029,GO:0070134,"Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.",positive regulation of mitochondrial translational initiation,biological_process
82030,GO:0070135,"The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.","beta-1,2-oligomannoside metabolic process",biological_process
82031,GO:0070136,"The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.","beta-1,2-oligomannoside biosynthetic process",biological_process
82032,GO:0070137,"Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).",ubiquitin-like protein-specific endopeptidase activity,molecular_function
82033,GO:0070139,Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.,SUMO-specific endopeptidase activity,molecular_function
82034,GO:0070141,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.",response to UV-A,biological_process
82035,GO:0070142,Evagination of a membrane to form a synaptic vesicle.,synaptic vesicle budding,biological_process
82036,GO:0070143,"The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial alanyl-tRNA aminoacylation,biological_process
82037,GO:0070144,"The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial arginyl-tRNA aminoacylation,biological_process
82038,GO:0070145,"The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial asparaginyl-tRNA aminoacylation,biological_process
82039,GO:0070146,"The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial aspartyl-tRNA aminoacylation,biological_process
82040,GO:0070147,"The process of coupling L-cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial cysteinyl-tRNA aminoacylation,biological_process
82041,GO:0070148,"The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial glutaminyl-tRNA aminoacylation,biological_process
82042,GO:0070149,"The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial glutamyl-tRNA aminoacylation,biological_process
82043,GO:0070150,"The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial glycyl-tRNA aminoacylation,biological_process
82044,GO:0070151,"The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial histidyl-tRNA aminoacylation,biological_process
82045,GO:0070152,"The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial isoleucyl-tRNA aminoacylation,biological_process
82046,GO:0070153,"The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial leucyl-tRNA aminoacylation,biological_process
82047,GO:0070154,"The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial lysyl-tRNA aminoacylation,biological_process
82048,GO:0070155,"The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial methionyl-tRNA aminoacylation,biological_process
82049,GO:0070156,"The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial phenylalanyl-tRNA aminoacylation,biological_process
82050,GO:0070157,"The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial prolyl-tRNA aminoacylation,biological_process
82051,GO:0070158,"The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial seryl-tRNA aminoacylation,biological_process
82052,GO:0070159,"The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial threonyl-tRNA aminoacylation,biological_process
82053,GO:0070160,A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.,tight junction,cellular_component
82054,GO:0070161,A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.,anchoring junction,cellular_component
82055,GO:0070162,"The regulated release of adiponectin, a protein hormone, by adipose tissue.",adiponectin secretion,biological_process
82056,GO:0070163,"Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.",regulation of adiponectin secretion,biological_process
82057,GO:0070164,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.",negative regulation of adiponectin secretion,biological_process
82058,GO:0070165,"Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.",positive regulation of adiponectin secretion,biological_process
82059,GO:0070166,"The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.",enamel mineralization,biological_process
82060,GO:0070167,"Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.",regulation of biomineral tissue development,biological_process
82061,GO:0070168,"Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.",negative regulation of biomineral tissue development,biological_process
82062,GO:0070169,"Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.",positive regulation of biomineral tissue development,biological_process
82063,GO:0070170,"Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.",regulation of tooth mineralization,biological_process
82064,GO:0070171,"Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.",negative regulation of tooth mineralization,biological_process
82065,GO:0070172,"Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.",positive regulation of tooth mineralization,biological_process
82066,GO:0070173,"Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.",regulation of enamel mineralization,biological_process
82067,GO:0070174,"Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.",negative regulation of enamel mineralization,biological_process
82068,GO:0070175,"Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.",positive regulation of enamel mineralization,biological_process
82069,GO:0070176,"A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.",DRM complex,cellular_component
82070,GO:0070177,The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.,contractile vacuole discharge,biological_process
82071,GO:0070179,"The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.",D-serine biosynthetic process,biological_process
82072,GO:0070180,"Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.",large ribosomal subunit rRNA binding,molecular_function
82073,GO:0070181,"Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.",small ribosomal subunit rRNA binding,molecular_function
82074,GO:0070182,Binding to a DNA polymerase.,DNA polymerase binding,molecular_function
82075,GO:0070183,"The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial tryptophanyl-tRNA aminoacylation,biological_process
82076,GO:0070184,"The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial tyrosyl-tRNA aminoacylation,biological_process
82077,GO:0070185,"The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.",mitochondrial valyl-tRNA aminoacylation,biological_process
82078,GO:0070186,"The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.",growth hormone activity,molecular_function
82079,GO:0070187,"A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two sub...",shelterin complex,cellular_component
82080,GO:0070192,A process of chromosome organization that is involved in a meiotic cell cycle.,chromosome organization involved in meiotic cell cycle,biological_process
82081,GO:0070193,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.",synaptonemal complex organization,biological_process
82082,GO:0070194,The controlled breakdown of a synaptonemal complex.,synaptonemal complex disassembly,biological_process
82083,GO:0070195,A receptor complex that consists of two identical subunits and binds growth hormone.,growth hormone receptor complex,cellular_component
82084,GO:0070196,"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.",eukaryotic translation initiation factor 3 complex assembly,biological_process
82085,GO:0070197,"The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.",meiotic attachment of telomere to nuclear envelope,biological_process
82086,GO:0070198,"Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.","protein localization to chromosome, telomeric region",biological_process
82087,GO:0070199,The directed movement of a protein to a specific location on a chromosome.,establishment of protein localization to chromosome,biological_process
82088,GO:0070200,The directed movement of a protein to a specific location in the telomeric region of a chromosome.,establishment of protein localization to telomere,biological_process
82089,GO:0070201,"Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.",regulation of establishment of protein localization,biological_process
82090,GO:0070202,"Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.",regulation of establishment of protein localization to chromosome,biological_process
82091,GO:0070203,"Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.",regulation of establishment of protein localization to telomere,biological_process
82092,GO:0070204,Catalysis of the reaction: 2-oxoglutarate + H+ + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2.,2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity,molecular_function
82093,GO:0070205,"Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.","2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity",molecular_function
82094,GO:0070206,"The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.",protein trimerization,biological_process
82095,GO:0070207,"The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.",protein homotrimerization,biological_process
82096,GO:0070208,"The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.",protein heterotrimerization,biological_process
82097,GO:0070210,"A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.",Rpd3L-Expanded complex,cellular_component
82098,GO:0070211,"A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.",Snt2C complex,cellular_component
82099,GO:0070212,"The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.",protein poly-ADP-ribosylation,biological_process
82100,GO:0070213,"The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.",protein auto-ADP-ribosylation,biological_process
82101,GO:0070214,"A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.",CSK-GAP-A.p62 complex,cellular_component
82102,GO:0070217,"The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.",transcription factor TFIIIB complex assembly,biological_process
82103,GO:0070224,Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.,sulfide:quinone oxidoreductase activity,molecular_function
82104,GO:0070225,Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.,sulfide dehydrogenase activity,molecular_function
82105,GO:0070227,"Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.",lymphocyte apoptotic process,biological_process
82106,GO:0070228,Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.,regulation of lymphocyte apoptotic process,biological_process
82107,GO:0070229,"Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.",negative regulation of lymphocyte apoptotic process,biological_process
82108,GO:0070230,"Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.",positive regulation of lymphocyte apoptotic process,biological_process
82109,GO:0070231,"Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.",T cell apoptotic process,biological_process
82110,GO:0070232,Any process that modulates the occurrence or rate of T cell death by apoptotic process.,regulation of T cell apoptotic process,biological_process
82111,GO:0070233,"Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.",negative regulation of T cell apoptotic process,biological_process
82112,GO:0070234,"Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.",positive regulation of T cell apoptotic process,biological_process
82113,GO:0070235,Any process that modulates the occurrence or rate of activation-induced cell death of T cells.,regulation of activation-induced cell death of T cells,biological_process
82114,GO:0070236,"Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.",negative regulation of activation-induced cell death of T cells,biological_process
82115,GO:0070237,"Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.",positive regulation of activation-induced cell death of T cells,biological_process
82116,GO:0070238,A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.,activated T cell autonomous cell death,biological_process
82117,GO:0070239,Any process that modulates the occurrence or rate of activated T cell autonomous cell death.,regulation of activated T cell autonomous cell death,biological_process
82118,GO:0070240,"Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.",negative regulation of activated T cell autonomous cell death,biological_process
82119,GO:0070241,"Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.",positive regulation of activated T cell autonomous cell death,biological_process
82120,GO:0070242,"Any apoptotic process in a thymocyte, an immature T cell located in the thymus.",thymocyte apoptotic process,biological_process
82121,GO:0070243,Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.,regulation of thymocyte apoptotic process,biological_process
82122,GO:0070244,"Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.",negative regulation of thymocyte apoptotic process,biological_process
82123,GO:0070245,"Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.",positive regulation of thymocyte apoptotic process,biological_process
82124,GO:0070246,"Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.",natural killer cell apoptotic process,biological_process
82125,GO:0070247,Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.,regulation of natural killer cell apoptotic process,biological_process
82126,GO:0070248,"Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.",negative regulation of natural killer cell apoptotic process,biological_process
82127,GO:0070249,"Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.",positive regulation of natural killer cell apoptotic process,biological_process
82128,GO:0070250,"The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.",mating projection membrane,cellular_component
82129,GO:0070251,Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.,pristanate-CoA ligase activity,molecular_function
82130,GO:0070252,The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.,actin-mediated cell contraction,biological_process
82131,GO:0070253,The regulated release of somatostatin from secretory granules in the D cells of the pancreas.,somatostatin secretion,biological_process
82132,GO:0070254,"The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.",mucus secretion,biological_process
82133,GO:0070255,"Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.",regulation of mucus secretion,biological_process
82134,GO:0070256,"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.",negative regulation of mucus secretion,biological_process
82135,GO:0070257,"Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.",positive regulation of mucus secretion,biological_process
82136,GO:0070258,A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.,inner membrane pellicle complex,cellular_component
82137,GO:0070259,Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.,tyrosyl-DNA phosphodiesterase activity,molecular_function
82138,GO:0070260,Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.,5'-tyrosyl-DNA phosphodiesterase activity,molecular_function
82139,GO:0070262,The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.,peptidyl-serine dephosphorylation,biological_process
82140,GO:0070263,The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.,external side of fungal-type cell wall,cellular_component
82141,GO:0070264,A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.,transcription factor TFIIIE complex,cellular_component
82142,GO:0070266,"A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic c...",necroptotic process,biological_process
82143,GO:0070268,"A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).",cornification,biological_process
82144,GO:0070269,"A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death.",pyroptotic inflammatory response,biological_process
82145,GO:0070273,"Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.",phosphatidylinositol-4-phosphate binding,molecular_function
82146,GO:0070274,"A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.",RES complex,cellular_component
82147,GO:0070276,"The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.",halogen metabolic process,biological_process
82148,GO:0070278,"The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.",extracellular matrix constituent secretion,biological_process
82149,GO:0070279,"Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.",vitamin B6 binding,molecular_function
82150,GO:0070280,"Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.",pyridoxal binding,molecular_function
82151,GO:0070281,"Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.",pyridoxamine binding,molecular_function
82152,GO:0070282,"Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.",pyridoxine binding,molecular_function
82153,GO:0070284,Catalysis of the reaction: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + CO + 5'-deoxyadenosine + formate + L-methionine + 3 H+.,phosphomethylpyrimidine synthase activity,molecular_function
82154,GO:0070285,"The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.",pigment cell development,biological_process
82155,GO:0070286,"The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.",axonemal dynein complex assembly,biological_process
82156,GO:0070287,"Combining with ferritin, and delivering ferritin into the cell via endocytosis.",ferritin receptor activity,molecular_function
82157,GO:0070288,"A protein complex that binds iron and acts as a major iron storage system. There are three major subclasses of ferritins: the classical ferritins (Ftn), the heme-containing bacterioferritins (Bfr) and the DNA-binding proteins from starved cells (Dps). Ftn and Bfr are made of 24 subunits, whereas Dps are smaller with 12 subunits. Ftn is found in most kindoms, while Bfr and Dps are restricted to prokaryotes.",ferritin complex,cellular_component
82158,GO:0070290,"Catalysis of the reaction: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine (NAPE) + H2O = an N-acylethanolamine (NAE) + a 1,2-diacyl-sn-glycero-3-phosphate + H+.",N-acylphosphatidylethanolamine-specific phospholipase D activity,molecular_function
82159,GO:0070291,The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.,N-acylethanolamine metabolic process,biological_process
82160,GO:0070292,The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.,N-acylphosphatidylethanolamine metabolic process,biological_process
82161,GO:0070293,"A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).",renal absorption,biological_process
82162,GO:0070294,"A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.",renal sodium ion absorption,biological_process
82163,GO:0070295,"A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.",renal water absorption,biological_process
82164,GO:0070296,"The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.",sarcoplasmic reticulum calcium ion transport,biological_process
82165,GO:0070297,"Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.",regulation of phosphorelay signal transduction system,biological_process
82166,GO:0070298,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.",negative regulation of phosphorelay signal transduction system,biological_process
82167,GO:0070299,"Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.",positive regulation of phosphorelay signal transduction system,biological_process
82168,GO:0070300,"Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.",phosphatidic acid binding,molecular_function
82169,GO:0070301,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.",cellular response to hydrogen peroxide,biological_process
82170,GO:0070302,"Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.",regulation of stress-activated protein kinase signaling cascade,biological_process
82171,GO:0070303,"Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.",negative regulation of stress-activated protein kinase signaling cascade,biological_process
82172,GO:0070304,"Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.",positive regulation of stress-activated protein kinase signaling cascade,biological_process
82173,GO:0070305,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.",response to cGMP,biological_process
82174,GO:0070306,"The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.",lens fiber cell differentiation,biological_process
82175,GO:0070307,"The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.",lens fiber cell development,biological_process
82176,GO:0070308,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.",lens fiber cell fate commitment,biological_process
82177,GO:0070309,"The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.",lens fiber cell morphogenesis,biological_process
82178,GO:0070310,A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.,ATR-ATRIP complex,cellular_component
82179,GO:0070311,"A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.",nucleosomal methylation activator complex,cellular_component
82180,GO:0070312,A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.,RAD52-ERCC4-ERCC1 complex,cellular_component
82181,GO:0070313,"A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.",RGS6-DNMT1-DMAP1 complex,cellular_component
82182,GO:0070314,"A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.",G1 to G0 transition,biological_process
82183,GO:0070315,"A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.",G1 to G0 transition involved in cell differentiation,biological_process
82184,GO:0070316,A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.,regulation of G0 to G1 transition,biological_process
82185,GO:0070317,"A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.",negative regulation of G0 to G1 transition,biological_process
82186,GO:0070318,A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.,positive regulation of G0 to G1 transition,biological_process
82187,GO:0070319,"A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.",Golgi to plasma membrane transport vesicle,cellular_component
82188,GO:0070320,"Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.",inward rectifier potassium channel inhibitor activity,molecular_function
82189,GO:0070324,"Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.",thyroid hormone binding,molecular_function
82190,GO:0070325,Binding to a lipoprotein particle receptor.,lipoprotein particle receptor binding,molecular_function
82191,GO:0070326,Binding to a very-low-density lipoprotein receptor.,very-low-density lipoprotein particle receptor binding,molecular_function
82192,GO:0070327,"The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",thyroid hormone transport,biological_process
82193,GO:0070328,Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.,triglyceride homeostasis,biological_process
82194,GO:0070329,The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.,tRNA seleno-modification,biological_process
82195,GO:0070330,"Catalysis of the reaction: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone = 17beta-estradiol + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Also converts androst-4-ene-3,17-dione into estrone.",aromatase activity,molecular_function
82196,GO:0070331,A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.,CD20-Lck-Fyn complex,cellular_component
82197,GO:0070332,"A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.",CD20-Lck-Lyn-Fyn complex,cellular_component
82198,GO:0070333,A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.,alpha6-beta4 integrin-Shc-Grb2 complex,cellular_component
82199,GO:0070334,A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.,alpha6-beta4 integrin-laminin 5 complex,cellular_component
82200,GO:0070335,"Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.",aspartate binding,molecular_function
82201,GO:0070336,Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.,flap-structured DNA binding,molecular_function
82202,GO:0070337,Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.,3'-flap-structured DNA binding,molecular_function
82203,GO:0070338,Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.,5'-flap-structured DNA binding,molecular_function
82204,GO:0070339,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.",response to bacterial lipopeptide,biological_process
82205,GO:0070340,The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.,detection of bacterial lipopeptide,biological_process
82206,GO:0070341,"The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.",fat cell proliferation,biological_process
82207,GO:0070342,"The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.",brown fat cell proliferation,biological_process
82208,GO:0070343,"The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.",white fat cell proliferation,biological_process
82209,GO:0070344,"Any process that modulates the frequency, rate or extent of fat cell proliferation.",regulation of fat cell proliferation,biological_process
82210,GO:0070345,Any process that stops or decreases the rate or extent of fat cell proliferation.,negative regulation of fat cell proliferation,biological_process
82211,GO:0070346,Any process that activates or increases the rate or extent of fat cell proliferation.,positive regulation of fat cell proliferation,biological_process
82212,GO:0070347,"Any process that modulates the frequency, rate or extent of brown fat cell proliferation.",regulation of brown fat cell proliferation,biological_process
82213,GO:0070348,Any process that stops or decreases the rate or extent of brown fat cell proliferation.,negative regulation of brown fat cell proliferation,biological_process
82214,GO:0070349,Any process that activates or increases the rate or extent of brown fat cell proliferation.,positive regulation of brown fat cell proliferation,biological_process
82215,GO:0070350,"Any process that modulates the frequency, rate or extent of white fat cell proliferation.",regulation of white fat cell proliferation,biological_process
82216,GO:0070351,Any process that stops or decreases the rate or extent of white fat cell proliferation.,negative regulation of white fat cell proliferation,biological_process
82217,GO:0070352,Any process that activates or increases the rate or extent of white fat cell proliferation.,positive regulation of white fat cell proliferation,biological_process
82218,GO:0070353,"A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.",GATA1-TAL1-TCF3-Lmo2 complex,cellular_component
82219,GO:0070354,"A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.",GATA2-TAL1-TCF3-Lmo2 complex,cellular_component
82220,GO:0070355,"A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).",synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex,cellular_component
82221,GO:0070356,"A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).",synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex,cellular_component
82222,GO:0070357,A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).,alphav-beta3 integrin-CD47 complex,cellular_component
82223,GO:0070358,A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.,actin polymerization-dependent cell motility,biological_process
82224,GO:0070360,"The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration from cell to cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated actin polymerization-dependent cell-to-cell migration in host,biological_process
82225,GO:0070365,"The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.",hepatocyte differentiation,biological_process
82226,GO:0070366,"Any process that modulates the frequency, rate or extent of hepatocyte differentiation.",regulation of hepatocyte differentiation,biological_process
82227,GO:0070367,Any process that stops or decreases the rate or extent of hepatocyte differentiation.,negative regulation of hepatocyte differentiation,biological_process
82228,GO:0070368,Any process that activates or increases the rate or extent of hepatocyte differentiation.,positive regulation of hepatocyte differentiation,biological_process
82229,GO:0070369,"A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.",beta-catenin-TCF7L2 complex,cellular_component
82230,GO:0070370,Any process that increases heat tolerance of a cell in response to high temperatures.,cellular heat acclimation,biological_process
82231,GO:0070371,"A MAPK cascade containing at least the ERK1 or ERK2 MAP kinases. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK1 or ERK2. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier. The ERK1/ERK2 cascade is activated by mitogens, growth factors, G protein-coupled receptors, and results in cellular responses such as cell proliferation, cell differentia...",ERK1 and ERK2 cascade,biological_process
82232,GO:0070372,"Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.",regulation of ERK1 and ERK2 cascade,biological_process
82233,GO:0070373,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.",negative regulation of ERK1 and ERK2 cascade,biological_process
82234,GO:0070374,"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.",positive regulation of ERK1 and ERK2 cascade,biological_process
82235,GO:0070375,"A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiatio...",ERK5 cascade,biological_process
82236,GO:0070376,"Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.",regulation of ERK5 cascade,biological_process
82237,GO:0070377,"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.",negative regulation of ERK5 cascade,biological_process
82238,GO:0070378,"Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.",positive regulation of ERK5 cascade,biological_process
82239,GO:0070379,Binding to high mobility group box 1 (HMBGB1).,high mobility group box 1 binding,molecular_function
82240,GO:0070380,Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,high mobility group box 1 receptor activity,molecular_function
82241,GO:0070381,"A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis.",endosome to plasma membrane transport vesicle,cellular_component
82242,GO:0070382,"A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.",exocytic vesicle,cellular_component
82243,GO:0070383,"The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.",DNA cytosine deamination,biological_process
82244,GO:0070384,"The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.",Harderian gland development,biological_process
82245,GO:0070385,A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.,egasyn-beta-glucuronidase complex,cellular_component
82246,GO:0070386,A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).,"procollagen-proline 4-dioxygenase complex, alpha(I) type",cellular_component
82247,GO:0070387,A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.,"procollagen-proline 4-dioxygenase complex, alpha(II) type",cellular_component
82248,GO:0070388,A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.,"procollagen-proline 4-dioxygenase complex, alpha(III) type",cellular_component
82249,GO:0070390,"A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.",transcription export complex 2,cellular_component
82250,GO:0070391,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.",response to lipoteichoic acid,biological_process
82251,GO:0070392,The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.,detection of lipoteichoic acid,biological_process
82252,GO:0070393,"The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.",teichoic acid catabolic process,biological_process
82253,GO:0070395,"The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.",lipoteichoic acid biosynthetic process,biological_process
82254,GO:0070396,"The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.",lipoteichoic acid catabolic process,biological_process
82255,GO:0070398,"The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.",wall teichoic acid biosynthetic process,biological_process
82256,GO:0070399,"The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.",wall teichoic acid catabolic process,biological_process
82257,GO:0070400,The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.,teichoic acid D-alanylation,biological_process
82258,GO:0070401,"Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.",NADP+ binding,molecular_function
82259,GO:0070402,"Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.",NADPH binding,molecular_function
82260,GO:0070403,"Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.",NAD+ binding,molecular_function
82261,GO:0070404,"Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.",NADH binding,molecular_function
82262,GO:0070405,Binding to ammonium ions (NH4+).,ammonium ion binding,molecular_function
82263,GO:0070406,"Binding to L-glutamine, 2,5-diamino-5-oxopentanoic acid.",L-glutamine binding,molecular_function
82264,GO:0070407,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.",oxidation-dependent protein catabolic process,biological_process
82265,GO:0070408,"The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.",carbamoyl phosphate metabolic process,biological_process
82266,GO:0070409,"The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.",carbamoyl phosphate biosynthetic process,biological_process
82267,GO:0070410,Binding to a common mediator SMAD signaling protein.,co-SMAD binding,molecular_function
82268,GO:0070411,Binding to an inhibitory SMAD signaling protein.,I-SMAD binding,molecular_function
82269,GO:0070412,Binding to a receptor-regulated SMAD signaling protein.,R-SMAD binding,molecular_function
82270,GO:0070417,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.",cellular response to cold,biological_process
82271,GO:0070418,"A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.",DNA-dependent protein kinase complex,cellular_component
82272,GO:0070419,A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.,nonhomologous end joining complex,cellular_component
82273,GO:0070420,"A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.",Ku-DNA ligase complex,cellular_component
82274,GO:0070421,"A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.",DNA ligase III-XRCC1 complex,cellular_component
82275,GO:0070422,A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.,G-protein beta/gamma-Raf-1 complex,cellular_component
82276,GO:0070424,"Any process that modulates the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.","regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",biological_process
82277,GO:0070425,"Any process that stops, prevents, or reduces the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.","negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",biological_process
82278,GO:0070426,"Any process that activates or increases the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.","positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",biological_process
82279,GO:0070427,"The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 1 (NOD1) protein receptor, and ending with regulation of a downstream cellular process.",nucleotide-binding oligomerization domain containing 1 signaling pathway,biological_process
82280,GO:0070428,"Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.",regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway,biological_process
82281,GO:0070429,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.",negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway,biological_process
82282,GO:0070430,"Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.",positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway,biological_process
82283,GO:0070431,"The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.",nucleotide-binding oligomerization domain containing 2 signaling pathway,biological_process
82284,GO:0070432,"Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.",regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway,biological_process
82285,GO:0070433,"Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.",negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway,biological_process
82286,GO:0070434,"Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.",positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway,biological_process
82287,GO:0070435,"A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.",Shc-EGFR complex,cellular_component
82288,GO:0070436,"A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.",Grb2-EGFR complex,cellular_component
82289,GO:0070437,"A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.",Grb2-Shc complex,cellular_component
82290,GO:0070439,"A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.",Mad-Max-mSin3A complex,cellular_component
82291,GO:0070440,"A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.",Mad-Max-mSin3B complex,cellular_component
82292,GO:0070441,"A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.",G-protein beta/gamma-Btk complex,cellular_component
82293,GO:0070442,An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.,integrin alphaIIb-beta3 complex,cellular_component
82294,GO:0070443,A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.,Mad-Max complex,cellular_component
82295,GO:0070444,"The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.",oligodendrocyte progenitor proliferation,biological_process
82296,GO:0070445,"Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.",regulation of oligodendrocyte progenitor proliferation,biological_process
82297,GO:0070446,Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.,negative regulation of oligodendrocyte progenitor proliferation,biological_process
82298,GO:0070447,Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.,positive regulation of oligodendrocyte progenitor proliferation,biological_process
82299,GO:0070448,Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.,laricitrin 5'-O-methyltransferase activity,molecular_function
82300,GO:0070449,"A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.",elongin complex,cellular_component
82301,GO:0070450,A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.,interleukin4-interleukin-4 receptor complex,cellular_component
82302,GO:0070451,"A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.",cell hair,cellular_component
82303,GO:0070452,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.",positive regulation of ergosterol biosynthetic process,biological_process
82304,GO:0070453,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.",regulation of heme biosynthetic process,biological_process
82305,GO:0070454,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.",negative regulation of heme biosynthetic process,biological_process
82306,GO:0070455,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.",positive regulation of heme biosynthetic process,biological_process
82307,GO:0070456,Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.,galactose-1-phosphate phosphatase activity,molecular_function
82308,GO:0070457,Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.,D-galactose-1-phosphate phosphatase activity,molecular_function
82309,GO:0070458,Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.,cellular detoxification of nitrogen compound,biological_process
82310,GO:0070459,"The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.",prolactin secretion,biological_process
82311,GO:0070460,"The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.",thyroid-stimulating hormone secretion,biological_process
82312,GO:0070461,"A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).",SAGA-type complex,cellular_component
82313,GO:0070462,The removal of tubulin heterodimers from the plus end of a microtubule.,plus-end specific microtubule depolymerization,biological_process
82314,GO:0070463,Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.,tubulin-dependent ATPase activity,molecular_function
82315,GO:0070464,A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.,alphav-beta3 integrin-collagen alpha3(VI) complex,cellular_component
82316,GO:0070465,A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.,alpha1-beta1 integrin-alpha3(VI) complex,cellular_component
82317,GO:0070466,A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.,alpha2-beta1 integrin-alpha3(VI) complex,cellular_component
82318,GO:0070467,"A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.",RC-1 DNA recombination complex,cellular_component
82319,GO:0070468,"The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.",dentin extracellular matrix secretion,biological_process
82320,GO:0070471,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.",uterine smooth muscle contraction,biological_process
82321,GO:0070472,"Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.",regulation of uterine smooth muscle contraction,biological_process
82322,GO:0070473,"Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.",negative regulation of uterine smooth muscle contraction,biological_process
82323,GO:0070474,"Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.",positive regulation of uterine smooth muscle contraction,biological_process
82324,GO:0070475,The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.,rRNA base methylation,biological_process
82325,GO:0070476,The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.,rRNA (guanine-N7)-methylation,biological_process
82326,GO:0070477,"An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.",endospore core,cellular_component
82327,GO:0070478,The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.,"nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay",biological_process
82328,GO:0070479,The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.,"nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay",biological_process
82329,GO:0070481,The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.,"nuclear-transcribed mRNA catabolic process, non-stop decay",biological_process
82330,GO:0070482,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.",response to oxygen levels,biological_process
82331,GO:0070483,"The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.",detection of hypoxia,biological_process
82332,GO:0070485,"The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.","dehydro-D-arabinono-1,4-lactone biosynthetic process",biological_process
82333,GO:0070486,The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.,leukocyte aggregation,biological_process
82334,GO:0070487,The adhesion of one monocyte to one or more other monocytes via adhesion molecules.,monocyte aggregation,biological_process
82335,GO:0070488,The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.,neutrophil aggregation,biological_process
82336,GO:0070489,The adhesion of one T cell to one or more other T cells via adhesion molecules.,T cell aggregation,biological_process
82337,GO:0070490,The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.,protein pupylation,biological_process
82338,GO:0070492,"Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.",oligosaccharide binding,molecular_function
82339,GO:0070493,"A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",thrombin-activated receptor signaling pathway,biological_process
82340,GO:0070494,"Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.",regulation of thrombin-activated receptor signaling pathway,biological_process
82341,GO:0070495,"Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.",negative regulation of thrombin-activated receptor signaling pathway,biological_process
82342,GO:0070496,"Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.",positive regulation of thrombin-activated receptor signaling pathway,biological_process
82343,GO:0070497,"Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.",6-carboxytetrahydropterin synthase activity,molecular_function
82344,GO:0070498,"The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-1-mediated signaling pathway,biological_process
82345,GO:0070499,"A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.",exosporium assembly,biological_process
82346,GO:0070501,"The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.",poly-gamma-glutamate biosynthetic process,biological_process
82347,GO:0070502,"The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.",capsule poly-gamma-glutamate biosynthetic process,biological_process
82348,GO:0070505,"A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV ...",pollen coat,cellular_component
82349,GO:0070506,Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.,high-density lipoprotein particle receptor activity,molecular_function
82350,GO:0070507,"Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.",regulation of microtubule cytoskeleton organization,biological_process
82351,GO:0070508,The directed movement of cholesterol into a cell or organelle.,cholesterol import,biological_process
82352,GO:0070509,The directed movement of calcium ions into a cell or organelle.,calcium ion import,biological_process
82353,GO:0070513,Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.,death domain binding,molecular_function
82354,GO:0070514,"A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.",SRF-myogenin-E12 complex,cellular_component
82355,GO:0070515,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.,alphaIIb-beta3 integrin-talin complex,cellular_component
82356,GO:0070516,A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.,CAK-ERCC2 complex,cellular_component
82357,GO:0070517,"A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.",DNA replication factor C core complex,cellular_component
82358,GO:0070518,"A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.",alpha4-beta1 integrin-CD53 complex,cellular_component
82359,GO:0070519,"A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.",alpha4-beta1 integrin-CD63 complex,cellular_component
82360,GO:0070520,"A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.",alpha4-beta1 integrin-CD81 complex,cellular_component
82361,GO:0070521,"A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.",alpha4-beta1 integrin-CD82 complex,cellular_component
82362,GO:0070522,"A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.",ERCC4-ERCC1 complex,cellular_component
82363,GO:0070523,Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.,11-beta-hydroxysteroid dehydrogenase (NAD+) activity,molecular_function
82364,GO:0070524,Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.,11-beta-hydroxysteroid dehydrogenase (NADP+) activity,molecular_function
82365,GO:0070527,The adhesion of one platelet to one or more other platelets via adhesion molecules.,platelet aggregation,biological_process
82366,GO:0070528,"A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.",protein kinase C signaling,biological_process
82367,GO:0070530,Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.,K63-linked polyubiquitin modification-dependent protein binding,molecular_function
82368,GO:0070531,"A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.",BRCA1-A complex,cellular_component
82369,GO:0070532,"A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.",BRCA1-B complex,cellular_component
82370,GO:0070533,"A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.",BRCA1-C complex,cellular_component
82371,GO:0070534,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.",protein K63-linked ubiquitination,biological_process
82372,GO:0070536,"A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.",protein K63-linked deubiquitination,biological_process
82373,GO:0070538,"Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.",oleic acid binding,molecular_function
82374,GO:0070539,"Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.",linoleic acid binding,molecular_function
82375,GO:0070540,"Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.",stearic acid binding,molecular_function
82376,GO:0070541,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.",response to platinum ion,biological_process
82377,GO:0070542,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.",response to fatty acid,biological_process
82378,GO:0070543,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.",response to linoleic acid,biological_process
82379,GO:0070545,"A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.",PeBoW complex,cellular_component
82380,GO:0070549,"An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs.",siRNA-mediated gene silencing by inhibition of translation,biological_process
82381,GO:0070550,"The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.",rDNA chromatin condensation,biological_process
82382,GO:0070551,"Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.","endoribonuclease activity, cleaving siRNA-paired mRNA",molecular_function
82383,GO:0070552,"A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.",BRISC complex,cellular_component
82384,GO:0070553,Combining with nicotinic acid to initiate a change in cell activity.,nicotinic acid receptor activity,molecular_function
82385,GO:0070554,"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).",synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex,cellular_component
82386,GO:0070555,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.",response to interleukin-1,biological_process
82387,GO:0070556,"A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.",TAF4B-containing transcription factor TFIID complex,cellular_component
82388,GO:0070557,A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.,PCNA-p21 complex,cellular_component
82389,GO:0070558,"A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.",alphaM-beta2 integrin-CD63 complex,cellular_component
82390,GO:0070559,"A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.",lysosomal multienzyme complex,cellular_component
82391,GO:0070560,The regulated release of proteins by a platelet or group of platelets.,protein secretion by platelet,biological_process
82392,GO:0070561,"A nuclear receptor-mediated signaling pathway initiated by vitamin D binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",vitamin D receptor signaling pathway,biological_process
82393,GO:0070562,"Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.",regulation of vitamin D receptor signaling pathway,biological_process
82394,GO:0070563,"Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.",negative regulation of vitamin D receptor signaling pathway,biological_process
82395,GO:0070564,"Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.",positive regulation of vitamin D receptor signaling pathway,biological_process
82396,GO:0070565,A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.,telomere-telomerase complex,cellular_component
82397,GO:0070566,Catalysis of the transfer of an adenylyl group to an acceptor.,adenylyltransferase activity,molecular_function
82398,GO:0070567,Catalysis of the transfer of a cytidylyl group to an acceptor.,cytidylyltransferase activity,molecular_function
82399,GO:0070568,Catalysis of the transfer of a guanylyl group to an acceptor.,guanylyltransferase activity,molecular_function
82400,GO:0070569,Catalysis of the transfer of an uridylyl group to an acceptor.,uridylyltransferase activity,molecular_function
82401,GO:0070570,"Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.",regulation of neuron projection regeneration,biological_process
82402,GO:0070571,"Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.",negative regulation of neuron projection regeneration,biological_process
82403,GO:0070572,"Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.",positive regulation of neuron projection regeneration,biological_process
82404,GO:0070573,"Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",metallodipeptidase activity,molecular_function
82405,GO:0070574,A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,cadmium ion transmembrane transport,biological_process
82406,GO:0070576,Catalysis of the hydroxylation of C-24 of any form of vitamin D.,vitamin D 24-hydroxylase activity,molecular_function
82407,GO:0070578,"A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex h...",RISC-loading complex,cellular_component
82408,GO:0070579,Catalysis of the reaction: 5-methylcytosine (5mC) in DNA + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine (5hmC) in DNA + succinate + CO2. This reaction is the first step in the removal of cytosine methylated on position 5 in double-stranded DNA. This activity can iteratively oxidize 5hmC to 5-formylcytosine (5fC) and to 5-carboxylcytosine (5caC).,DNA 5-methylcytosine dioxygenase activity,molecular_function
82409,GO:0070580,"The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, w...",base J metabolic process,biological_process
82410,GO:0070581,"A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.",rolling circle DNA replication,biological_process
82411,GO:0070582,A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.,theta DNA replication,biological_process
82412,GO:0070583,The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.,spore membrane bending pathway,biological_process
82413,GO:0070585,"A process in which a protein is transported to, or maintained in, a location within the mitochondrion.",protein localization to mitochondrion,biological_process
82414,GO:0070586,The attachment of one cell to another cell affecting gastrulation.,cell-cell adhesion involved in gastrulation,biological_process
82415,GO:0070587,"Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.",regulation of cell-cell adhesion involved in gastrulation,biological_process
82416,GO:0070588,A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,calcium ion transmembrane transport,biological_process
82417,GO:0070590,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.",spore wall biogenesis,biological_process
82418,GO:0070591,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.",ascospore wall biogenesis,biological_process
82419,GO:0070592,The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.,cell wall polysaccharide biosynthetic process,biological_process
82420,GO:0070593,The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.,dendrite self-avoidance,biological_process
82421,GO:0070594,"Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.",juvenile hormone response element binding,molecular_function
82422,GO:0070596,"The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.",(1->3)-alpha-glucan biosynthetic process,biological_process
82423,GO:0070598,"The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.",cell wall (1->3)-alpha-glucan biosynthetic process,biological_process
82424,GO:0070600,"The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.",fungal-type cell wall (1->3)-alpha-glucan biosynthetic process,biological_process
82425,GO:0070601,The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.,centromeric sister chromatid cohesion,biological_process
82426,GO:0070602,"Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.",regulation of centromeric sister chromatid cohesion,biological_process
82427,GO:0070603,"A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.",SWI/SNF superfamily-type complex,cellular_component
82428,GO:0070606,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.",regulation of (1->3)-alpha-glucan biosynthetic process,biological_process
82429,GO:0070608,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.",regulation of cell wall (1->3)-alpha-glucan biosynthetic process,biological_process
82430,GO:0070610,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.",regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process,biological_process
82431,GO:0070611,Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.,histone H3R2 methyltransferase activity,molecular_function
82432,GO:0070612,Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H2A.,histone H2AR3 methyltransferase activity,molecular_function
82433,GO:0070613,"Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.",regulation of protein processing,biological_process
82434,GO:0070614,"The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.",tungstate ion transport,biological_process
82435,GO:0070616,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.",regulation of thiamine diphosphate biosynthetic process,biological_process
82436,GO:0070617,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.",negative regulation of thiamine diphosphate biosynthetic process,biological_process
82437,GO:0070618,"A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.",Grb2-Sos complex,cellular_component
82438,GO:0070619,"A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.",Shc-Grb2-Sos complex,cellular_component
82439,GO:0070620,"A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.",EGFR-Grb2-Sos complex,cellular_component
82440,GO:0070621,"A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.",EGFR-Shc-Grb2-Sos complex,cellular_component
82441,GO:0070622,"A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.",UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex,cellular_component
82442,GO:0070623,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.",regulation of thiamine biosynthetic process,biological_process
82443,GO:0070624,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.",negative regulation of thiamine biosynthetic process,biological_process
82444,GO:0070625,"The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.",zymogen granule exocytosis,biological_process
82445,GO:0070626,Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.,(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity,molecular_function
82446,GO:0070628,"Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.",proteasome binding,molecular_function
82447,GO:0070630,"The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.",(1->4)-alpha-glucan biosynthetic process,biological_process
82448,GO:0070631,"Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.",spindle pole body localization,biological_process
82449,GO:0070633,The directed movement of a substance from one side of an epithelium to the other.,transepithelial transport,biological_process
82450,GO:0070634,The directed movement of ammonium ions from one side of an epithelium to the other.,transepithelial ammonium transport,biological_process
82451,GO:0070635,Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.,nicotinamide riboside hydrolase activity,molecular_function
82452,GO:0070636,Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.,nicotinic acid riboside hydrolase activity,molecular_function
82453,GO:0070637,"The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.",pyridine nucleoside metabolic process,biological_process
82454,GO:0070638,"The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.",pyridine nucleoside catabolic process,biological_process
82455,GO:0070640,"The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.",vitamin D3 metabolic process,biological_process
82456,GO:0070644,"Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.",vitamin D response element binding,molecular_function
82457,GO:0070645,"A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.",Ubisch body,cellular_component
82458,GO:0070646,"A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.",protein modification by small protein removal,biological_process
82459,GO:0070647,"A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.",protein modification by small protein conjugation or removal,biological_process
82460,GO:0070648,"An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.",formin-nucleated actin cable,cellular_component
82461,GO:0070649,"The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.",formin-nucleated actin cable assembly,biological_process
82462,GO:0070650,Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.,actin filament bundle distribution,biological_process
82463,GO:0070651,"An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.",nonfunctional rRNA decay,biological_process
82464,GO:0070652,"A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.",HAUS complex,cellular_component
82465,GO:0070653,Binding to a high-density lipoprotein receptor.,high-density lipoprotein particle receptor binding,molecular_function
82466,GO:0070654,The regrowth of a sensory epithelium following its loss or destruction.,sensory epithelium regeneration,biological_process
82467,GO:0070655,The regrowth of lost or destroyed mechanosensory epithelia.,mechanosensory epithelium regeneration,biological_process
82468,GO:0070656,Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.,mechanoreceptor differentiation involved in mechanosensory epithelium regeneration,biological_process
82469,GO:0070657,The regrowth of a neuromast following its loss or destruction.,neuromast regeneration,biological_process
82470,GO:0070658,Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.,neuromast hair cell differentiation involved in neuromast regeneration,biological_process
82471,GO:0070659,The regrowth of lost or destroyed inner ear sensory epithelia.,inner ear sensory epithelium regeneration,biological_process
82472,GO:0070660,Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.,inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration,biological_process
82473,GO:0070661,The expansion of a leukocyte population by cell division.,leukocyte proliferation,biological_process
82474,GO:0070662,The expansion of a mast cell population by cell division.,mast cell proliferation,biological_process
82475,GO:0070663,"Any process that modulates the frequency, rate or extent of leukocyte proliferation.",regulation of leukocyte proliferation,biological_process
82476,GO:0070664,"Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.",negative regulation of leukocyte proliferation,biological_process
82477,GO:0070665,"Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.",positive regulation of leukocyte proliferation,biological_process
82478,GO:0070666,"Any process that modulates the frequency, rate or extent of mast cell proliferation.",regulation of mast cell proliferation,biological_process
82479,GO:0070667,"Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.",negative regulation of mast cell proliferation,biological_process
82480,GO:0070668,Any process that activates or increases the rate or extent of mast cell proliferation.,positive regulation of mast cell proliferation,biological_process
82481,GO:0070669,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.",response to interleukin-2,biological_process
82482,GO:0070670,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.",response to interleukin-4,biological_process
82483,GO:0070671,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.",response to interleukin-12,biological_process
82484,GO:0070672,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.",response to interleukin-15,biological_process
82485,GO:0070673,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.",response to interleukin-18,biological_process
82486,GO:0070674,Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.,hypoxanthine dehydrogenase activity,molecular_function
82487,GO:0070675,Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.,hypoxanthine oxidase activity,molecular_function
82488,GO:0070676,The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.,intralumenal vesicle formation,biological_process
82489,GO:0070677,Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.,rRNA (cytosine-2'-O-ribose)-methyltransferase activity,molecular_function
82490,GO:0070678,"Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.",preprotein binding,molecular_function
82491,GO:0070679,"Binding to inositol 1,4,5 trisphosphate.","inositol 1,4,5 trisphosphate binding",molecular_function
82492,GO:0070681,"A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.",glutaminyl-tRNAGln biosynthesis via transamidation,biological_process
82493,GO:0070682,"The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.",proteasome regulatory particle assembly,biological_process
82494,GO:0070684,"The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.",seminal clot liquefaction,biological_process
82495,GO:0070685,"A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.",macropinocytic cup,cellular_component
82496,GO:0070686,The portion of the plasma membrane surrounding a macropinocytic cup.,macropinocytic cup membrane,cellular_component
82497,GO:0070687,The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.,macropinocytic cup cytoskeleton,cellular_component
82498,GO:0070691,"A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.",P-TEFb complex,cellular_component
82499,GO:0070692,"A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).",CTDK-1 complex,cellular_component
82500,GO:0070693,A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.,P-TEFb-cap methyltransferase complex,cellular_component
82501,GO:0070694,Catalysis of the reaction: 5-hydroxymethyl-dUMP + H2O = 2-deoxy-D-ribose 5-phosphate + 5-hydroxymethyluracil.,5-hydroxymethyl-dUMP N-hydrolase activity,molecular_function
82502,GO:0070695,"A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).",FHF complex,cellular_component
82503,GO:0070696,Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.,transmembrane receptor protein serine/threonine kinase binding,molecular_function
82504,GO:0070697,Binding to an activin receptor.,activin receptor binding,molecular_function
82505,GO:0070698,Binding to a type I activin receptor.,type I activin receptor binding,molecular_function
82506,GO:0070699,Binding to a type II activin receptor.,type II activin receptor binding,molecular_function
82507,GO:0070700,Binding to a BMP receptor.,BMP receptor binding,molecular_function
82508,GO:0070701,"An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.",mucus layer,cellular_component
82509,GO:0070702,"The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.",inner mucus layer,cellular_component
82510,GO:0070703,The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.,outer mucus layer,cellular_component
82511,GO:0070704,Catalysis of the introduction of a double bond into a sterol molecule.,sterol desaturase activity,molecular_function
82512,GO:0070705,The modification of an RNA molecule by insertion of one or more nucleotides.,RNA nucleotide insertion,biological_process
82513,GO:0070706,The modification of an RNA molecule by removal of a single nucleotide.,RNA nucleotide deletion,biological_process
82514,GO:0070707,The modification of an RNA molecule by insertion of a dinucleotide.,RNA dinucleotide insertion,biological_process
82515,GO:0070708,The modification of an RNA molecule by insertion of a cytidine nucleotide.,RNA cytidine insertion,biological_process
82516,GO:0070709,The modification of an RNA molecule by insertion of a guanosine nucleotide.,RNA guanosine insertion,biological_process
82517,GO:0070710,The modification of an RNA molecule by removal of a uridine nucleotide.,RNA uridine deletion,biological_process
82518,GO:0070711,The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.,RNA adenosine-uridine insertion,biological_process
82519,GO:0070712,The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.,RNA cytidine-uridine insertion,biological_process
82520,GO:0070713,The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.,RNA guanosine-cytidine insertion,biological_process
82521,GO:0070714,The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.,RNA guanosine-uridine insertion,biological_process
82522,GO:0070715,"The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sodium-dependent organic cation transport,biological_process
82523,GO:0070716,A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.,mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication,biological_process
82524,GO:0070717,Binding to a stretch of purines (adenine or guanine) in an RNA molecule.,poly-purine tract binding,molecular_function
82525,GO:0070718,"A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.",alphaPDGFR-SHP-2 complex,cellular_component
82526,GO:0070719,"A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.",alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex,cellular_component
82527,GO:0070720,"A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.",Grb2-SHP-2 complex,cellular_component
82528,GO:0070721,A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.,ISGF3 complex,cellular_component
82529,GO:0070722,"A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.",Tle3-Aes complex,cellular_component
82530,GO:0070723,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.",response to cholesterol,biological_process
82531,GO:0070724,A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.,BMP receptor complex,cellular_component
82532,GO:0070725,A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.,Yb body,cellular_component
82533,GO:0070726,"The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.",cell wall assembly,biological_process
82534,GO:0070728,"Binding to L-leucine, 2-amino-4-methylpentanoic acid.",L-leucine binding,molecular_function
82535,GO:0070729,"The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.",cyclic nucleotide transport,biological_process
82536,GO:0070730,"The directed movement of cyclic AMP (cAMP), into, out of or within a cell.",cAMP transport,biological_process
82537,GO:0070731,"The directed movement of cyclic GMP (cGMP), into, out of or within a cell.",cGMP transport,biological_process
82538,GO:0070732,"An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.",spindle envelope,cellular_component
82539,GO:0070733,"Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to L-serine, L-threonine, and L-tyrosine residues in target proteins.",AMPylase activity,molecular_function
82540,GO:0070735,Catalysis of the reaction: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H+ + phosphate.,protein-glycine ligase activity,molecular_function
82541,GO:0070736,Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.,"protein-glycine ligase activity, initiating",molecular_function
82542,GO:0070737,"Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.","protein-glycine ligase activity, elongating",molecular_function
82543,GO:0070738,Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.,tubulin-glycine ligase activity,molecular_function
82544,GO:0070739,Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.,protein-glutamic acid ligase activity,molecular_function
82545,GO:0070740,Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.,tubulin-glutamic acid ligase activity,molecular_function
82546,GO:0070741,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.",response to interleukin-6,biological_process
82547,GO:0070742,"Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.",C2H2 zinc finger domain binding,molecular_function
82548,GO:0070743,"A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.",interleukin-23 complex,cellular_component
82549,GO:0070744,A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.,interleukin-27 complex,cellular_component
82550,GO:0070745,"A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.",interleukin-35 complex,cellular_component
82551,GO:0070746,Binding to interleukin-35.,interleukin-35 binding,molecular_function
82552,GO:0070747,Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,interleukin-35 receptor activity,molecular_function
82553,GO:0070748,Binding to an interleukin-35 receptor.,interleukin-35 receptor binding,molecular_function
82554,GO:0070753,"The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-35 production,biological_process
82555,GO:0070754,"Any process that modulates the frequency, rate, or extent of interleukin-35 production.",regulation of interleukin-35 production,biological_process
82556,GO:0070755,"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.",negative regulation of interleukin-35 production,biological_process
82557,GO:0070756,"Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.",positive regulation of interleukin-35 production,biological_process
82558,GO:0070757,"The series of molecular signals initiated by interleukin-35 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-35-mediated signaling pathway,biological_process
82559,GO:0070758,"Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway.",regulation of interleukin-35-mediated signaling pathway,biological_process
82560,GO:0070759,"Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.",negative regulation of interleukin-35-mediated signaling pathway,biological_process
82561,GO:0070760,"Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.",positive regulation of interleukin-35-mediated signaling pathway,biological_process
82562,GO:0070761,"A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.",pre-snoRNP complex,cellular_component
82563,GO:0070762,"A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.",nuclear pore transmembrane ring,cellular_component
82564,GO:0070763,A protein complex that consists of homodimer of the Notch ligand Delta1.,Delta1 complex,cellular_component
82565,GO:0070764,A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.,gamma-secretase-Delta1 complex,cellular_component
82566,GO:0070765,"A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four co...",gamma-secretase complex,cellular_component
82567,GO:0070766,"A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).",endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex,cellular_component
82568,GO:0070767,"A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.",BRCA1-Rad51 complex,cellular_component
82569,GO:0070768,"A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).",synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex,cellular_component
82570,GO:0070769,"A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.",alphaIIb-beta3 integrin-CIB complex,cellular_component
82571,GO:0070770,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.,alphaIIb-beta3 integrin-CD47-FAK complex,cellular_component
82572,GO:0070771,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.,alphaIIb-beta3 integrin-CD47-Src complex,cellular_component
82573,GO:0070772,"A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.",PAS complex,cellular_component
82574,GO:0070773,Catalysis of the reaction: N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal glutamine residue of a protein.,protein-N-terminal glutamine amidohydrolase activity,molecular_function
82575,GO:0070775,A multisubunit complex that catalyzes the acetylation of histone H3.,H3 histone acetyltransferase complex,cellular_component
82576,GO:0070776,"A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.",MOZ/MORF histone acetyltransferase complex,cellular_component
82577,GO:0070777,"The process in which D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid  is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore.",D-aspartate transmembrane transport,biological_process
82578,GO:0070778,The directed movement of L-aspartate across a membrane by means of some agent such as a transporter or a pore.,L-aspartate transmembrane transport,biological_process
82579,GO:0070779,The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.,D-aspartate import across plasma membrane,biological_process
82580,GO:0070780,Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.,dihydrosphingosine-1-phosphate phosphatase activity,molecular_function
82581,GO:0070781,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.",response to biotin,biological_process
82582,GO:0070782,"A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.",phosphatidylserine exposure on apoptotic cell surface,biological_process
82583,GO:0070783,"A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.",growth of unicellular organism as a thread of attached cells,biological_process
82584,GO:0070784,"Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.",regulation of growth of unicellular organism as a thread of attached cells,biological_process
82585,GO:0070785,"Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.",negative regulation of growth of unicellular organism as a thread of attached cells,biological_process
82586,GO:0070786,"Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.",positive regulation of growth of unicellular organism as a thread of attached cells,biological_process
82587,GO:0070787,"The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.",conidiophore development,biological_process
82588,GO:0070788,"The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.",conidiophore stalk development,biological_process
82589,GO:0070789,"The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.",metula development,biological_process
82590,GO:0070790,"The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.",phialide development,biological_process
82591,GO:0070791,"The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.",cleistothecium development,biological_process
82592,GO:0070792,"The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.",Hulle cell development,biological_process
82593,GO:0070793,"Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.",regulation of conidiophore development,biological_process
82594,GO:0070794,"Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.",negative regulation of conidiophore development,biological_process
82595,GO:0070795,"Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.",positive regulation of conidiophore development,biological_process
82596,GO:0070796,"Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.",regulation of cleistothecium development,biological_process
82597,GO:0070797,"Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.",negative regulation of cleistothecium development,biological_process
82598,GO:0070798,"Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.",positive regulation of cleistothecium development,biological_process
82599,GO:0070799,"Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.",regulation of conidiophore stalk development,biological_process
82600,GO:0070800,"Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.",negative regulation of conidiophore stalk development,biological_process
82601,GO:0070801,"Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.",positive regulation of conidiophore stalk development,biological_process
82602,GO:0070802,"Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.",regulation of metula development,biological_process
82603,GO:0070803,"Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.",negative regulation of metula development,biological_process
82604,GO:0070804,"Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.",positive regulation of metula development,biological_process
82605,GO:0070805,"Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.",regulation of phialide development,biological_process
82606,GO:0070806,"Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.",negative regulation of phialide development,biological_process
82607,GO:0070807,"Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.",positive regulation of phialide development,biological_process
82608,GO:0070808,"Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.",regulation of Hulle cell development,biological_process
82609,GO:0070809,"Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.",negative regulation of Hulle cell development,biological_process
82610,GO:0070810,"Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.",positive regulation of Hulle cell development,biological_process
82611,GO:0070811,The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.,glycerol-2-phosphate transmembrane transport,biological_process
82612,GO:0070813,"The chemical reactions and pathways involving hydrogen sulfide, H2S.",hydrogen sulfide metabolic process,biological_process
82613,GO:0070814,"The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.",hydrogen sulfide biosynthetic process,biological_process
82614,GO:0070815,Catalysis of the reaction: L-lysyl-[protein] + 2-oxoglutarate + O2 = (5S)-5-hydroxy-L-lysyl-[protein] + succinate + CO2.,peptidyl-lysine 5-dioxygenase activity,molecular_function
82615,GO:0070817,"Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.",P-TEFb-cap methyltransferase complex localization,biological_process
82616,GO:0070818,Catalysis of the reaction: protoporphyrinogen IX + 3 acceptor = protoporphyrin IX + 3 reduced acceptor.,protoporphyrinogen oxidase activity,molecular_function
82617,GO:0070819,Catalysis of the reaction: protoporphyrinogen IX + 3 a quinone = protoporphyrin IX + 3 a quinol.,"protoporphyrinogen oxidase activity, quinone as acceptor",molecular_function
82618,GO:0070820,A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.,tertiary granule,cellular_component
82619,GO:0070821,The lipid bilayer surrounding a tertiary granule.,tertiary granule membrane,cellular_component
82620,GO:0070822,"Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a var...",Sin3-type complex,cellular_component
82621,GO:0070823,A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.,HDA1 complex,cellular_component
82622,GO:0070824,"A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.",SHREC complex,cellular_component
82623,GO:0070825,A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.,chrorion micropyle,cellular_component
82624,GO:0070826,"A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.",paraferritin complex,cellular_component
82625,GO:0070828,"Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.",heterochromatin organization,biological_process
82626,GO:0070830,"The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.",bicellular tight junction assembly,biological_process
82627,GO:0070831,"The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.",basement membrane assembly,biological_process
82628,GO:0070835,Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.,chromium ion transmembrane transporter activity,molecular_function
82629,GO:0070836,"The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.",caveola assembly,biological_process
82630,GO:0070837,"The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.",dehydroascorbic acid transport,biological_process
82631,GO:0070840,"Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.",dynein complex binding,molecular_function
82632,GO:0070841,"The aggregation, arrangement and bonding together of a set of components to form an inclusion body.",inclusion body assembly,biological_process
82633,GO:0070842,"The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.",aggresome assembly,biological_process
82634,GO:0070843,"The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.",misfolded protein transport,biological_process
82635,GO:0070844,"The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.",polyubiquitinated protein transport,biological_process
82636,GO:0070845,"The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.",polyubiquitinated misfolded protein transport,biological_process
82637,GO:0070846,The modification of an Hsp90 protein by removal of acetyl groups.,Hsp90 deacetylation,biological_process
82638,GO:0070847,"A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; ...",core mediator complex,cellular_component
82639,GO:0070848,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.",response to growth factor,biological_process
82640,GO:0070849,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.",response to epidermal growth factor,biological_process
82641,GO:0070850,"A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.",TACC/TOG complex,cellular_component
82642,GO:0070851,Binding to a growth factor receptor.,growth factor receptor binding,molecular_function
82643,GO:0070852,A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.,cell body fiber,cellular_component
82644,GO:0070853,"Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.",myosin VI binding,molecular_function
82645,GO:0070854,Binding to a heavy chain of a myosin VI complex.,myosin VI heavy chain binding,molecular_function
82646,GO:0070855,Binding to the head/neck region of a myosin VI heavy chain.,myosin VI head/neck binding,molecular_function
82647,GO:0070856,Binding to a light chain of a myosin VI complex.,myosin VI light chain binding,molecular_function
82648,GO:0070857,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.",regulation of bile acid biosynthetic process,biological_process
82649,GO:0070858,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.",negative regulation of bile acid biosynthetic process,biological_process
82650,GO:0070859,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.",positive regulation of bile acid biosynthetic process,biological_process
82651,GO:0070860,"A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.",RNA polymerase I core factor complex,cellular_component
82652,GO:0070864,"A cellular structure that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.",sperm individualization complex,cellular_component
82653,GO:0070865,A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.,investment cone,cellular_component
82654,GO:0070866,Binding to a protein or protein complex in the presence of sterols.,sterol-dependent protein binding,molecular_function
82655,GO:0070867,The portion of the plasma membrane surrounding a mating projection tip.,mating projection tip membrane,cellular_component
82656,GO:0070873,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.",regulation of glycogen metabolic process,biological_process
82657,GO:0070874,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.",negative regulation of glycogen metabolic process,biological_process
82658,GO:0070875,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.",positive regulation of glycogen metabolic process,biological_process
82659,GO:0070876,"A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.",SOSS complex,cellular_component
82660,GO:0070877,"A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3'...",microprocessor complex,cellular_component
82661,GO:0070878,"Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.",primary miRNA binding,molecular_function
82662,GO:0070879,"The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.",fungal-type cell wall beta-glucan metabolic process,biological_process
82663,GO:0070880,"The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.",fungal-type cell wall beta-glucan biosynthetic process,biological_process
82664,GO:0070881,"Any process that modulates the frequency, rate or extent of proline transport.",regulation of proline transport,biological_process
82665,GO:0070883,"Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.",pre-miRNA binding,molecular_function
82666,GO:0070884,"Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.",regulation of calcineurin-NFAT signaling cascade,biological_process
82667,GO:0070885,"Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.",negative regulation of calcineurin-NFAT signaling cascade,biological_process
82668,GO:0070886,"Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.",positive regulation of calcineurin-NFAT signaling cascade,biological_process
82669,GO:0070887,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.",cellular response to chemical stimulus,biological_process
82670,GO:0070888,"Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.",E-box binding,molecular_function
82671,GO:0070889,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.",platelet alpha granule organization,biological_process
82672,GO:0070891,Binding to lipoteichoic acid.,lipoteichoic acid binding,molecular_function
82673,GO:0070892,Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.,lipoteichoic acid immune receptor activity,molecular_function
82674,GO:0070897,The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides.,transcription preinitiation complex assembly,biological_process
82675,GO:0070898,"The formation of a large multiprotein-DNA complex that self-assembles on a tRNA gene through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC), (which includes BDP1, BRF1, TBP, TFIIIC in human). The PIC engages RNA polymerase III on its DNA template strand and sparks polymerization of the first few RNA nucleotides.",RNA polymerase III preinitiation complex assembly,biological_process
82676,GO:0070899,The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.,mitochondrial tRNA wobble uridine modification,biological_process
82677,GO:0070900,The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.,mitochondrial tRNA modification,biological_process
82678,GO:0070901,The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.,mitochondrial tRNA methylation,biological_process
82679,GO:0070902,The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.,mitochondrial tRNA pseudouridine synthesis,biological_process
82680,GO:0070903,The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.,mitochondrial tRNA thio-modification,biological_process
82681,GO:0070905,Binding to 2-amino-3-hydroxypropanoic acid.,serine binding,molecular_function
82682,GO:0070906,Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).,aspartate:alanine antiporter activity,molecular_function
82683,GO:0070907,Catalysis of the reaction: L-histidine(out) + histamine(in) = L-histidine(in) + histamine(out).,L-histidine:histamine antiporter activity,molecular_function
82684,GO:0070908,Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).,tyrosine:tyramine antiporter activity,molecular_function
82685,GO:0070909,Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).,glutamate:gamma-aminobutyric acid antiporter activity,molecular_function
82686,GO:0070911,The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.,global genome nucleotide-excision repair,biological_process
82687,GO:0070912,A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.,Ddb1-Ckn1 complex,cellular_component
82688,GO:0070913,A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.,Ddb1-Wdr21 complex,cellular_component
82689,GO:0070914,A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).,UV-damage excision repair,biological_process
82690,GO:0070915,"Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.",lysophosphatidic acid receptor activity,molecular_function
82691,GO:0070916,"A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).",inositol phosphoceramide synthase complex,cellular_component
82692,GO:0070917,Binds to and modulates the activity of inositol phosphoceramide synthase.,inositol phosphoceramide synthase regulator activity,molecular_function
82693,GO:0070918,A process leading to the generation of a functional regulatory non-coding RNA.,regulatory ncRNA processing,biological_process
82694,GO:0070920,"Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing.",regulation of regulatory ncRNA processing,biological_process
82695,GO:0070921,"Any process that modulates the frequency, rate or extent of siRNA processing.",regulation of siRNA processing,biological_process
82696,GO:0070922,"The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA.",RISC complex assembly,biological_process
82697,GO:0070925,"The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",organelle assembly,biological_process
82698,GO:0070929,A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.,trans-translation,biological_process
82699,GO:0070930,A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.,trans-translation-dependent protein tagging,biological_process
82700,GO:0070931,The volume enclosed by the membrane of a Golgi-associated vesicle.,Golgi-associated vesicle lumen,cellular_component
82701,GO:0070934,An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).,CRD-mediated mRNA stabilization,biological_process
82702,GO:0070935,An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.,3'-UTR-mediated mRNA stabilization,biological_process
82703,GO:0070936,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.",protein K48-linked ubiquitination,biological_process
82704,GO:0070937,"A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.",CRD-mediated mRNA stability complex,cellular_component
82705,GO:0070938,"A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.",contractile ring,cellular_component
82706,GO:0070939,"A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.",Dsl1/NZR complex,cellular_component
82707,GO:0070941,"The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.",eisosome assembly,biological_process
82708,GO:0070942,The directed killing of a target cell by a neutrophil.,neutrophil mediated cytotoxicity,biological_process
82709,GO:0070943,The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.,neutrophil-mediated killing of symbiont cell,biological_process
82710,GO:0070944,The directed killing of a bacterium by a neutrophil.,neutrophil-mediated killing of bacterium,biological_process
82711,GO:0070945,The directed killing of a gram-negative bacterium by a neutrophil.,neutrophil-mediated killing of gram-negative bacterium,biological_process
82712,GO:0070946,The directed killing of a gram-positive bacterium by a neutrophil.,neutrophil-mediated killing of gram-positive bacterium,biological_process
82713,GO:0070947,The directed killing of a fungal cell by a neutrophil.,neutrophil-mediated killing of fungus,biological_process
82714,GO:0070948,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.",regulation of neutrophil mediated cytotoxicity,biological_process
82715,GO:0070949,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.",regulation of neutrophil mediated killing of symbiont cell,biological_process
82716,GO:0070950,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.",regulation of neutrophil mediated killing of bacterium,biological_process
82717,GO:0070951,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.",regulation of neutrophil mediated killing of gram-negative bacterium,biological_process
82718,GO:0070952,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.",regulation of neutrophil mediated killing of gram-positive bacterium,biological_process
82719,GO:0070953,"Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.",regulation of neutrophil mediated killing of fungus,biological_process
82720,GO:0070954,"Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.",negative regulation of neutrophil mediated cytotoxicity,biological_process
82721,GO:0070955,"Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.",negative regulation of neutrophil mediated killing of symbiont cell,biological_process
82722,GO:0070956,"Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.",negative regulation of neutrophil mediated killing of bacterium,biological_process
82723,GO:0070957,"Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.",negative regulation of neutrophil mediated killing of gram-negative bacterium,biological_process
82724,GO:0070958,"Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.",negative regulation of neutrophil mediated killing of gram-positive bacterium,biological_process
82725,GO:0070959,"Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.",negative regulation of neutrophil mediated killing of fungus,biological_process
82726,GO:0070960,"Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.",positive regulation of neutrophil mediated cytotoxicity,biological_process
82727,GO:0070961,"Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.",positive regulation of neutrophil mediated killing of symbiont cell,biological_process
82728,GO:0070962,"Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.",positive regulation of neutrophil mediated killing of bacterium,biological_process
82729,GO:0070963,"Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.",positive regulation of neutrophil mediated killing of gram-negative bacterium,biological_process
82730,GO:0070964,"Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.",positive regulation of neutrophil mediated killing of gram-positive bacterium,biological_process
82731,GO:0070965,"Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.",positive regulation of neutrophil mediated killing of fungus,biological_process
82732,GO:0070966,The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.,"nuclear-transcribed mRNA catabolic process, no-go decay",biological_process
82733,GO:0070967,"Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.",coenzyme F420 binding,molecular_function
82734,GO:0070968,"Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.",pyrroloquinoline quinone binding,molecular_function
82735,GO:0070971,An endoplasmic reticulum part at which COPII-coated vesicles are produced.,endoplasmic reticulum exit site,cellular_component
82736,GO:0070972,"A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.",protein localization to endoplasmic reticulum,biological_process
82737,GO:0070974,Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.,POU domain binding,molecular_function
82738,GO:0070975,"Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.",FHA domain binding,molecular_function
82739,GO:0070976,"Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.",TIR domain binding,molecular_function
82740,GO:0070977,"A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.",bone maturation,biological_process
82741,GO:0070978,Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.,voltage-gated calcium channel complex assembly,biological_process
82742,GO:0070979,"A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.",protein K11-linked ubiquitination,biological_process
82743,GO:0070980,"The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).",biphenyl catabolic process,biological_process
82744,GO:0070981,"The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.",L-asparagine biosynthetic process,biological_process
82745,GO:0070983,The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.,dendrite guidance,biological_process
82746,GO:0070984,"Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.",SET domain binding,molecular_function
82747,GO:0070985,"A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.",transcription factor TFIIK complex,cellular_component
82748,GO:0070986,"The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).",left/right axis specification,biological_process
82749,GO:0070987,"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not in...",error-free translesion synthesis,biological_process
82750,GO:0070988,The process of removing one or more methyl groups from a molecule.,demethylation,biological_process
82751,GO:0070989,"The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.",oxidative demethylation,biological_process
82752,GO:0070990,Binding to a small nuclear ribonucleoprotein particle.,snRNP binding,molecular_function
82753,GO:0070991,"Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.",medium-chain fatty acyl-CoA dehydrogenase activity,molecular_function
82754,GO:0070992,"A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.",translation initiation complex,cellular_component
82755,GO:0070993,"A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.",cytosolic translation preinitiation complex,cellular_component
82756,GO:0070994,The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.,detection of oxidative stress,biological_process
82757,GO:0070996,Binding to a type 1 melanocortin receptor.,type 1 melanocortin receptor binding,molecular_function
82758,GO:0070998,"The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of gravity,biological_process
82759,GO:0071000,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.",response to magnetism,biological_process
82760,GO:0071001,"A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.",U4/U6 snRNP,cellular_component
82761,GO:0071002,"A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.",U4atac/U6atac snRNP,cellular_component
82762,GO:0071003,"A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.",penta-snRNP complex,cellular_component
82763,GO:0071004,"A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.",U2-type prespliceosome,cellular_component
82764,GO:0071005,"A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.",U2-type precatalytic spliceosome,cellular_component
82765,GO:0071006,"A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.",U2-type catalytic step 1 spliceosome,cellular_component
82766,GO:0071007,"A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.",U2-type catalytic step 2 spliceosome,cellular_component
82767,GO:0071008,"A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.",U2-type post-mRNA release spliceosomal complex,cellular_component
82768,GO:0071009,A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.,U4atac/U6atac x U5 tri-snRNP complex,cellular_component
82769,GO:0071010,"A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.",prespliceosome,cellular_component
82770,GO:0071011,"A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.",precatalytic spliceosome,cellular_component
82771,GO:0071012,"A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.",catalytic step 1 spliceosome,cellular_component
82772,GO:0071013,"A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.",catalytic step 2 spliceosome,cellular_component
82773,GO:0071014,"A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, either U2 or U12, U5, and either U6 or U6atac.",post-mRNA release spliceosomal complex,cellular_component
82774,GO:0071015,A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.,U12-type prespliceosome,cellular_component
82775,GO:0071016,"A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.",U12-type precatalytic spliceosome,cellular_component
82776,GO:0071017,"A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.",U12-type catalytic step 1 spliceosome,cellular_component
82777,GO:0071018,"A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.",U12-type catalytic step 2 spliceosome,cellular_component
82778,GO:0071019,"A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.",U12-type post-mRNA release spliceosomal complex,cellular_component
82779,GO:0071020,"A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.",post-spliceosomal complex,cellular_component
82780,GO:0071021,"A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.",U2-type post-spliceosomal complex,cellular_component
82781,GO:0071022,"A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.",U12-type post-spliceosomal complex,cellular_component
82782,GO:0071023,"A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.",trans spliceosomal complex,cellular_component
82783,GO:0071024,A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.,SL snRNP,cellular_component
82784,GO:0071025,A process that identifies and degrades defective or aberrant RNAs.,RNA surveillance,biological_process
82785,GO:0071026,The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.,cytoplasmic RNA surveillance,biological_process
82786,GO:0071027,A process that identifies and degrades defective or aberrant RNAs within the nucleus.,nuclear RNA surveillance,biological_process
82787,GO:0071028,A process that identifies and degrades defective or aberrant mRNAs within the nucleus.,nuclear mRNA surveillance,biological_process
82788,GO:0071030,The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.,nuclear mRNA surveillance of spliceosomal pre-mRNA splicing,biological_process
82789,GO:0071031,The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.,nuclear mRNA surveillance of mRNA 3'-end processing,biological_process
82790,GO:0071032,The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.,nuclear mRNA surveillance of mRNP export,biological_process
82791,GO:0071034,The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).,CUT catabolic process,biological_process
82792,GO:0071035,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.",nuclear polyadenylation-dependent rRNA catabolic process,biological_process
82793,GO:0071036,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.",nuclear polyadenylation-dependent snoRNA catabolic process,biological_process
82794,GO:0071037,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.",nuclear polyadenylation-dependent snRNA catabolic process,biological_process
82795,GO:0071038,"A nuclear tRNA surveillance pathway, dependent on the TRAMP exosome adaptor and the nuclear exosome.",TRAMP-dependent tRNA surveillance pathway,biological_process
82796,GO:0071039,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.",nuclear polyadenylation-dependent CUT catabolic process,biological_process
82797,GO:0071040,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.",nuclear polyadenylation-dependent antisense transcript catabolic process,biological_process
82798,GO:0071041,"The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.",antisense RNA transcript catabolic process,biological_process
82799,GO:0071042,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.",nuclear polyadenylation-dependent mRNA catabolic process,biological_process
82800,GO:0071044,The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).,histone mRNA catabolic process,biological_process
82801,GO:0071045,The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.,nuclear histone mRNA catabolic process,biological_process
82802,GO:0071046,"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.",nuclear polyadenylation-dependent ncRNA catabolic process,biological_process
82803,GO:0071047,"The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.",polyadenylation-dependent mRNA catabolic process,biological_process
82804,GO:0071051,Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.,poly(A)-dependent snoRNA 3'-end processing,biological_process
82805,GO:0071052,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.,alpha9-beta1 integrin-ADAM1 complex,cellular_component
82806,GO:0071053,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.,alpha9-beta1 integrin-ADAM2 complex,cellular_component
82807,GO:0071054,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.,alpha9-beta1 integrin-ADAM3 complex,cellular_component
82808,GO:0071055,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.,alpha9-beta1 integrin-ADAM9 complex,cellular_component
82809,GO:0071056,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.,alpha9-beta1 integrin-ADAM15 complex,cellular_component
82810,GO:0071057,A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.,alphav-beta3 integrin-ADAM15 complex,cellular_component
82811,GO:0071058,A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.,alpha3-beta1 integrin-CD151 complex,cellular_component
82812,GO:0071059,A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.,alpha6-beta1 integrin-CD151 complex,cellular_component
82813,GO:0071060,A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.,alpha7-beta1 integrin-CD151 complex,cellular_component
82814,GO:0071061,A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.,alpha6-beta4 integrin-CD151 complex,cellular_component
82815,GO:0071062,A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.,alphav-beta3 integrin-vitronectin complex,cellular_component
82816,GO:0071063,"The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.",sensory perception of wind,biological_process
82817,GO:0071064,A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.,alphaE-beta7 integrin-E-cadherin complex,cellular_component
82818,GO:0071065,A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.,alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex,cellular_component
82819,GO:0071067,A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.,alphav-beta3 integrin-ADAM23 complex,cellular_component
82820,GO:0071068,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.,alpha9-beta1 integrin-ADAM12 complex,cellular_component
82821,GO:0071069,A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.,alpha4-beta1 integrin-thrombospondin-1 complex,cellular_component
82822,GO:0071070,A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.,alpha4-beta1 integrin-thrombospondin-2 complex,cellular_component
82823,GO:0071071,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.",regulation of phospholipid biosynthetic process,biological_process
82824,GO:0071072,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.",negative regulation of phospholipid biosynthetic process,biological_process
82825,GO:0071073,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.",positive regulation of phospholipid biosynthetic process,biological_process
82826,GO:0071074,"Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.",eukaryotic initiation factor eIF2 binding,molecular_function
82827,GO:0071075,"A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.",CUGBP1-eIF2 complex,cellular_component
82828,GO:0071077,"Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.","adenosine 3',5'-bisphosphate transmembrane transporter activity",molecular_function
82829,GO:0071078,"A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.",fibronectin-tissue transglutaminase complex,cellular_component
82830,GO:0071079,A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.,alpha2-beta1 integrin-chondroadherin complex,cellular_component
82831,GO:0071080,A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.,alpha3-beta1 integrin-basigin complex,cellular_component
82832,GO:0071081,A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.,alpha3-beta1 integrin-CD63 complex,cellular_component
82833,GO:0071082,A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.,alpha9-beta1 integrin-tenascin complex,cellular_component
82834,GO:0071083,A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).,alphaV-beta3 integrin-CD47-FCER2 complex,cellular_component
82835,GO:0071084,A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.,alpha2-beta1 integrin-CD47 complex,cellular_component
82836,GO:0071085,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.,alphaIIb-beta3 integrin-CD9 complex,cellular_component
82837,GO:0071086,"A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.",alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex,cellular_component
82838,GO:0071087,A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.,alpha11-beta1 integrin-collagen type I complex,cellular_component
82839,GO:0071088,A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.,alpha5-beta1 integrin-tissue transglutaminase complex,cellular_component
82840,GO:0071089,A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.,alphaV-beta3 integrin-tissue transglutaminase complex,cellular_component
82841,GO:0071090,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.,alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex,cellular_component
82842,GO:0071091,A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.,alpha1-beta1 integrin-tissue transglutaminase complex,cellular_component
82843,GO:0071092,A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.,alpha3-beta1 integrin-tissue transglutaminase complex,cellular_component
82844,GO:0071093,A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.,alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex,cellular_component
82845,GO:0071094,A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.,alpha6-beta4 integrin-CD9 complex,cellular_component
82846,GO:0071095,A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.,alpha3-beta1 integrin-thrombospondin complex,cellular_component
82847,GO:0071096,A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.,alphaV-beta3 integrin-gelsolin complex,cellular_component
82848,GO:0071097,A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.,alphaV-beta3 integrin-paxillin-Pyk2 complex,cellular_component
82849,GO:0071098,A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.,alpha6-beta4 integrin-Fyn complex,cellular_component
82850,GO:0071099,A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).,alphaV-beta6 integrin-TGFbeta-3 complex,cellular_component
82851,GO:0071100,A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).,alphaV-beta8 integrin-MMP14-TGFbeta-1 complex,cellular_component
82852,GO:0071101,A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.,alpha4-beta1 integrin-JAM2 complex,cellular_component
82853,GO:0071102,A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.,alpha4-beta1 integrin-paxillin complex,cellular_component
82854,GO:0071103,"A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.",DNA conformation change,biological_process
82855,GO:0071104,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.",response to interleukin-9,biological_process
82856,GO:0071105,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.",response to interleukin-11,biological_process
82857,GO:0071106,"The process in which adenosine 3',5'-bisphosphate is transported across a membrane.","adenosine 3',5'-bisphosphate transmembrane transport",biological_process
82858,GO:0071107,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.",response to parathyroid hormone,biological_process
82859,GO:0071108,"A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.",protein K48-linked deubiquitination,biological_process
82860,GO:0071109,"The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.",superior temporal gyrus development,biological_process
82861,GO:0071111,"Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.",cyclic-guanylate-specific phosphodiesterase activity,molecular_function
82862,GO:0071112,A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).,alpha4-beta4 integrin-EMILIN-1 complex,cellular_component
82863,GO:0071113,A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.,alphaIIb-beta3 integrin-ICAM-4 complex,cellular_component
82864,GO:0071114,"A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.",alphaV-beta3 integrin-tumstatin complex,cellular_component
82865,GO:0071115,"A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.",alpha5-beta1 integrin-endostatin complex,cellular_component
82866,GO:0071116,"A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.",alpha6-beta1 integrin-CYR61 complex,cellular_component
82867,GO:0071117,A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.,alpha5-beta1 integrin-fibronectin-NOV complex,cellular_component
82868,GO:0071118,A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.,alphaV-beta3 integrin-NOV complex,cellular_component
82869,GO:0071119,"A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).",alpha7-beta1 integrin-nicotinamide riboside kinase complex,cellular_component
82870,GO:0071120,A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.,alpha4-beta1 integrin-CD47 complex,cellular_component
82871,GO:0071121,A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.,alpha9-beta1 integrin-VEGF-D complex,cellular_component
82872,GO:0071122,A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.,alpha9-beta1 integrin-VEGF-A complex,cellular_component
82873,GO:0071123,A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.,alpha9-beta1 integrin-VEGF-C complex,cellular_component
82874,GO:0071124,A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.,alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex,cellular_component
82875,GO:0071125,A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.,alphaV-beta3 integrin-EGFR complex,cellular_component
82876,GO:0071126,A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.,alphaV-beta6 integrin-osteopontin complex,cellular_component
82877,GO:0071127,A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.,alpha9-beta1 integrin-osteopontin complex,cellular_component
82878,GO:0071128,A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.,alpha5-beta1 integrin-osteopontin complex,cellular_component
82879,GO:0071129,A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.,alphaV-beta3 integrin-LPP3 complex,cellular_component
82880,GO:0071130,A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.,alpha5-beta1 integrin-LPP3 complex,cellular_component
82881,GO:0071131,A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.,alphaV-beta3 integrin-laminin alpha-4 complex,cellular_component
82882,GO:0071132,A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.,alphaX-beta2 integrin-ICAM-4 complex,cellular_component
82883,GO:0071133,A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.,alpha9-beta1 integrin-ADAM8 complex,cellular_component
82884,GO:0071134,A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.,alpha9-beta1 integrin-thrombospondin-1 complex,cellular_component
82885,GO:0071135,A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.,alpha7-beta1 integrin-focal adhesion kinase complex,cellular_component
82886,GO:0071136,A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.,alpha7-beta1 integrin-laminin alpha-2 complex,cellular_component
82887,GO:0071137,A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.,alphaV-beta3 integrin-CD98 complex,cellular_component
82888,GO:0071138,A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.,alpha5-beta5-fibronectin-SFRP2 complex,cellular_component
82889,GO:0071139,"The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.",resolution of DNA recombination intermediates,biological_process
82890,GO:0071140,"The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.",resolution of mitotic recombination intermediates,biological_process
82891,GO:0071141,A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.,SMAD protein complex,cellular_component
82892,GO:0071142,"A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.",homomeric SMAD protein complex,cellular_component
82893,GO:0071144,"A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or...",heteromeric SMAD protein complex,cellular_component
82894,GO:0071152,A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.,G-protein alpha(q)-synembrin complex,cellular_component
82895,GO:0071153,A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.,G-protein alpha(o)-synembrin complex,cellular_component
82896,GO:0071154,A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.,G-protein alpha(i)1-synembrin complex,cellular_component
82897,GO:0071155,A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.,G-protein alpha(13)-synembrin complex,cellular_component
82898,GO:0071159,"A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene e...",NF-kappaB complex,cellular_component
82899,GO:0071160,Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.,cyanophycin synthetase activity (L-aspartate-adding),molecular_function
82900,GO:0071161,Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.,cyanophycin synthetase activity (L-arginine-adding),molecular_function
82901,GO:0071162,"A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.",CMG complex,cellular_component
82902,GO:0071163,"The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.",DNA replication preinitiation complex assembly,biological_process
82903,GO:0071164,"Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.",RNA cap trimethylguanosine synthase activity,molecular_function
82904,GO:0071165,"The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.",GINS complex assembly,biological_process
82905,GO:0071166,"Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.",ribonucleoprotein complex localization,biological_process
82906,GO:0071168,"Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.",protein localization to chromatin,biological_process
82907,GO:0071169,The directed movement of a protein to a part of a chromosome that is organized into chromatin.,establishment of protein localization to chromatin,biological_process
82908,GO:0071170,A DNA replication termination process that takes place at a specific termination site.,site-specific DNA replication termination,biological_process
82909,GO:0071171,"A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.",site-specific DNA replication termination at RTS1 barrier,biological_process
82910,GO:0071172,"Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.",dihydromonapterin reductase activity,molecular_function
82911,GO:0071173,A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.,spindle assembly checkpoint signaling,biological_process
82912,GO:0071174,"A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.",mitotic spindle checkpoint signaling,biological_process
82913,GO:0071175,"A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML2-RBP-Jkappa-ICN1 complex,cellular_component
82914,GO:0071176,"A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML2-RBP-Jkappa-ICN2 complex,cellular_component
82915,GO:0071177,"A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML2-RBP-Jkappa-ICN3 complex,cellular_component
82916,GO:0071178,"A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML2-RBP-Jkappa-ICN4 complex,cellular_component
82917,GO:0071179,"A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML3-RBP-Jkappa-ICN1 complex,cellular_component
82918,GO:0071180,"A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML3-RBP-Jkappa-ICN2 complex,cellular_component
82919,GO:0071181,"A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML3-RBP-Jkappa-ICN3 complex,cellular_component
82920,GO:0071182,"A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.",MAML3-RBP-Jkappa-ICN4 complex,cellular_component
82921,GO:0071183,"A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-protocadherin-gamma complex,cellular_component
82922,GO:0071184,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v4-protocadherin-gamma-a1 complex,cellular_component
82923,GO:0071185,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v4-protocadherin-gamma-a3 complex,cellular_component
82924,GO:0071186,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v4-protocadherin-gamma-b2 complex,cellular_component
82925,GO:0071187,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v4-protocadherin-gamma-b4 complex,cellular_component
82926,GO:0071188,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v7-protocadherin-gamma-a1 complex,cellular_component
82927,GO:0071189,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v7-protocadherin-gamma-a3 complex,cellular_component
82928,GO:0071190,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v7-protocadherin-gamma-b2 complex,cellular_component
82929,GO:0071191,"A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.",protocadherin-alpha-v7-protocadherin-gamma-b4 complex,cellular_component
82930,GO:0071192,A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.,Kv4.2-KChIP1 channel complex,cellular_component
82931,GO:0071193,A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.,Kv4.2-KChIP2 channel complex,cellular_component
82932,GO:0071194,A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.,Kv4.2-KChIP3 channel complex,cellular_component
82933,GO:0071195,A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.,Kv4.2-KChIP4 channel complex,cellular_component
82934,GO:0071196,A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.,Kv4.3-KChIP1 channel complex,cellular_component
82935,GO:0071197,A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.,Kv4.2-Kv4.3 channel complex,cellular_component
82936,GO:0071198,A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.,Kv4.1-DPP6 channel complex,cellular_component
82937,GO:0071199,A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.,Kv4.1-DPP10 channel complex,cellular_component
82938,GO:0071200,A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.,Kv4.2-DPP6 channel complex,cellular_component
82939,GO:0071201,A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.,Kv4.3-DPP6 channel complex,cellular_component
82940,GO:0071202,A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.,Kv4.3-DPP10 channel complex,cellular_component
82941,GO:0071203,"A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.",WASH complex,cellular_component
82942,GO:0071204,"A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.",histone pre-mRNA 3'end processing complex,cellular_component
82943,GO:0071205,"Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.",protein localization to juxtaparanode region of axon,biological_process
82944,GO:0071206,The directed movement of a protein to the juxtaparanode region of an axon.,establishment of protein localization to juxtaparanode region of axon,biological_process
82945,GO:0071207,Binding to a conserved stem-loop structure found in histone pre-mRNAs.,histone pre-mRNA stem-loop binding,molecular_function
82946,GO:0071208,Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.,histone pre-mRNA DCP binding,molecular_function
82947,GO:0071209,Binding to a U7 small nuclear RNA (U7 snRNA).,U7 snRNA binding,molecular_function
82948,GO:0071210,"The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.",protein insertion into membrane raft,biological_process
82949,GO:0071211,"The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.",protein targeting to vacuole involved in autophagy,biological_process
82950,GO:0071212,An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.,subsynaptic reticulum,cellular_component
82951,GO:0071213,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.",cellular response to 1-aminocyclopropane-1-carboxylic acid,biological_process
82952,GO:0071214,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.",cellular response to abiotic stimulus,biological_process
82953,GO:0071215,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.",cellular response to abscisic acid stimulus,biological_process
82954,GO:0071216,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.",cellular response to biotic stimulus,biological_process
82955,GO:0071217,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.",cellular response to external biotic stimulus,biological_process
82956,GO:0071218,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.",cellular response to misfolded protein,biological_process
82957,GO:0071219,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.",cellular response to molecule of bacterial origin,biological_process
82958,GO:0071220,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.",cellular response to bacterial lipoprotein,biological_process
82959,GO:0071221,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.",cellular response to bacterial lipopeptide,biological_process
82960,GO:0071222,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.",cellular response to lipopolysaccharide,biological_process
82961,GO:0071223,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.",cellular response to lipoteichoic acid,biological_process
82962,GO:0071224,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.",cellular response to peptidoglycan,biological_process
82963,GO:0071225,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.",cellular response to muramyl dipeptide,biological_process
82964,GO:0071226,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.",cellular response to molecule of fungal origin,biological_process
82965,GO:0071227,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.",cellular response to molecule of oomycetes origin,biological_process
82966,GO:0071228,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.",cellular response to tumor cell,biological_process
82967,GO:0071229,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.",cellular response to acid chemical,biological_process
82968,GO:0071230,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.",cellular response to amino acid stimulus,biological_process
82969,GO:0071231,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.",cellular response to folic acid,biological_process
82970,GO:0071232,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.",cellular response to histidine,biological_process
82971,GO:0071233,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus.",cellular response to L-leucine,biological_process
82972,GO:0071234,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.",cellular response to phenylalanine,biological_process
82973,GO:0071235,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.",cellular response to proline,biological_process
82974,GO:0071236,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.",cellular response to antibiotic,biological_process
82975,GO:0071237,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.",cellular response to bacteriocin,biological_process
82976,GO:0071238,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.",cellular response to brefeldin A,biological_process
82977,GO:0071239,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.",cellular response to streptomycin,biological_process
82978,GO:0071240,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.",cellular response to food,biological_process
82979,GO:0071242,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.",cellular response to ammonium ion,biological_process
82980,GO:0071243,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.",cellular response to arsenic-containing substance,biological_process
82981,GO:0071244,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.",cellular response to carbon dioxide,biological_process
82982,GO:0071245,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.",cellular response to carbon monoxide,biological_process
82983,GO:0071246,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.",cellular response to chlorate,biological_process
82984,GO:0071247,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.",cellular response to chromate,biological_process
82985,GO:0071248,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.",cellular response to metal ion,biological_process
82986,GO:0071249,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.",cellular response to nitrate,biological_process
82987,GO:0071250,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.",cellular response to nitrite,biological_process
82988,GO:0071251,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.",cellular response to silicon dioxide,biological_process
82989,GO:0071252,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.",cellular response to sulfur dioxide,biological_process
82990,GO:0071253,"Binding to a connexin, any of a group of related proteins that assemble to form gap junctions.",connexin binding,molecular_function
82991,GO:0071254,A focus in the cytoplasm that contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.,cytoplasmic U snRNP body,cellular_component
82992,GO:0071255,"A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).",Cvt vesicle assembly,biological_process
82993,GO:0071256,"A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.",translocon complex,cellular_component
82994,GO:0071257,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.",cellular response to electrical stimulus,biological_process
82995,GO:0071258,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.",cellular response to gravity,biological_process
82996,GO:0071259,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.",cellular response to magnetism,biological_process
82997,GO:0071260,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.",cellular response to mechanical stimulus,biological_process
82998,GO:0071261,"A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.",Ssh1 translocon complex,cellular_component
82999,GO:0071262,"Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.",regulation of translational initiation in response to starvation,biological_process
83000,GO:0071263,"Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.",negative regulation of translational initiation in response to starvation,biological_process
83001,GO:0071264,"Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.",positive regulation of translational initiation in response to starvation,biological_process
83002,GO:0071265,"The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.",L-methionine biosynthetic process,biological_process
83003,GO:0071266,"The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components such as L-aspartate or L-homoserine. This process occurs in plants, bacteria, archae and fungi.",'de novo' L-methionine biosynthetic process,biological_process
83004,GO:0071267,"Any process that generates L-methionine from derivatives of it, without de novo synthesis.",L-methionine salvage,biological_process
83005,GO:0071269,The chemical reactions and pathways resulting in the formation of L-homocysteine.,L-homocysteine biosynthetic process,biological_process
83006,GO:0071271,"The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.",1-butanol biosynthetic process,biological_process
83007,GO:0071272,"The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.",morphine metabolic process,biological_process
83008,GO:0071273,"The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.",morphine catabolic process,biological_process
83009,GO:0071274,"The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.",isoquinoline alkaloid catabolic process,biological_process
83010,GO:0071275,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.",cellular response to aluminum ion,biological_process
83011,GO:0071276,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.",cellular response to cadmium ion,biological_process
83012,GO:0071277,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.",cellular response to calcium ion,biological_process
83013,GO:0071278,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.",cellular response to cesium ion,biological_process
83014,GO:0071279,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.",cellular response to cobalt ion,biological_process
83015,GO:0071280,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.",cellular response to copper ion,biological_process
83016,GO:0071281,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.",cellular response to iron ion,biological_process
83017,GO:0071282,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.",cellular response to iron(II) ion,biological_process
83018,GO:0071283,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.",cellular response to iron(III) ion,biological_process
83019,GO:0071284,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.",cellular response to lead ion,biological_process
83020,GO:0071285,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.",cellular response to lithium ion,biological_process
83021,GO:0071286,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.",cellular response to magnesium ion,biological_process
83022,GO:0071287,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.",cellular response to manganese ion,biological_process
83023,GO:0071288,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.",cellular response to mercury ion,biological_process
83024,GO:0071289,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.",cellular response to nickel ion,biological_process
83025,GO:0071290,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.",cellular response to platinum ion,biological_process
83026,GO:0071291,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.",cellular response to selenium ion,biological_process
83027,GO:0071292,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver (Ag+) ion stimulus.",cellular response to silver ion,biological_process
83028,GO:0071293,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.",cellular response to tellurium ion,biological_process
83029,GO:0071294,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.",cellular response to zinc ion,biological_process
83030,GO:0071295,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.",cellular response to vitamin,biological_process
83031,GO:0071296,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.",cellular response to biotin,biological_process
83032,GO:0071297,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.",cellular response to cobalamin,biological_process
83033,GO:0071298,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.",cellular response to L-ascorbic acid,biological_process
83034,GO:0071299,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.",cellular response to vitamin A,biological_process
83035,GO:0071300,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.",cellular response to retinoic acid,biological_process
83036,GO:0071301,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.",cellular response to vitamin B1,biological_process
83037,GO:0071302,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.",cellular response to vitamin B2,biological_process
83038,GO:0071303,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.",cellular response to vitamin B3,biological_process
83039,GO:0071304,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.",cellular response to vitamin B6,biological_process
83040,GO:0071305,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.",cellular response to vitamin D,biological_process
83041,GO:0071306,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.",cellular response to vitamin E,biological_process
83042,GO:0071307,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.",cellular response to vitamin K,biological_process
83043,GO:0071308,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.",cellular response to menaquinone,biological_process
83044,GO:0071309,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.",cellular response to phylloquinone,biological_process
83045,GO:0071311,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.",cellular response to acetate,biological_process
83046,GO:0071312,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.",cellular response to alkaloid,biological_process
83047,GO:0071313,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.",cellular response to caffeine,biological_process
83048,GO:0071314,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.",cellular response to cocaine,biological_process
83049,GO:0071315,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.",cellular response to morphine,biological_process
83050,GO:0071316,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.",cellular response to nicotine,biological_process
83051,GO:0071317,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.",cellular response to isoquinoline alkaloid,biological_process
83052,GO:0071318,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.",cellular response to ATP,biological_process
83053,GO:0071319,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.",cellular response to benzoic acid,biological_process
83054,GO:0071320,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.",cellular response to cAMP,biological_process
83055,GO:0071321,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.",cellular response to cGMP,biological_process
83056,GO:0071322,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.",cellular response to carbohydrate stimulus,biological_process
83057,GO:0071323,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.",cellular response to chitin,biological_process
83058,GO:0071324,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.",cellular response to disaccharide stimulus,biological_process
83059,GO:0071325,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.",cellular response to mannitol stimulus,biological_process
83060,GO:0071326,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.",cellular response to monosaccharide stimulus,biological_process
83061,GO:0071327,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.",cellular response to trehalose stimulus,biological_process
83062,GO:0071328,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.",cellular response to maltose stimulus,biological_process
83063,GO:0071329,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.",cellular response to sucrose stimulus,biological_process
83064,GO:0071330,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.",cellular response to trehalose-6-phosphate stimulus,biological_process
83065,GO:0071331,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.",cellular response to hexose stimulus,biological_process
83066,GO:0071332,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.",cellular response to fructose stimulus,biological_process
83067,GO:0071333,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.",cellular response to glucose stimulus,biological_process
83068,GO:0071334,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.",cellular response to rhamnose stimulus,biological_process
83069,GO:0071335,"The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.",hair follicle cell proliferation,biological_process
83070,GO:0071336,"Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.",regulation of hair follicle cell proliferation,biological_process
83071,GO:0071337,"Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.",negative regulation of hair follicle cell proliferation,biological_process
83072,GO:0071338,Any process that activates or increases the rate or extent of hair follicle cell proliferation.,positive regulation of hair follicle cell proliferation,biological_process
83073,GO:0071339,"A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.",MLL1 complex,cellular_component
83074,GO:0071340,"The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.",skeletal muscle acetylcholine-gated channel clustering,biological_process
83075,GO:0071341,"A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.",medial cortical node,cellular_component
83076,GO:0071344,"The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.",diphosphate metabolic process,biological_process
83077,GO:0071345,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.",cellular response to cytokine stimulus,biological_process
83078,GO:0071346,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.",cellular response to type II interferon,biological_process
83079,GO:0071347,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.",cellular response to interleukin-1,biological_process
83080,GO:0071348,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.",cellular response to interleukin-11,biological_process
83081,GO:0071349,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.",cellular response to interleukin-12,biological_process
83082,GO:0071350,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.",cellular response to interleukin-15,biological_process
83083,GO:0071351,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.",cellular response to interleukin-18,biological_process
83084,GO:0071352,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.",cellular response to interleukin-2,biological_process
83085,GO:0071353,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.",cellular response to interleukin-4,biological_process
83086,GO:0071354,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.",cellular response to interleukin-6,biological_process
83087,GO:0071355,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.",cellular response to interleukin-9,biological_process
83088,GO:0071356,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.",cellular response to tumor necrosis factor,biological_process
83089,GO:0071357,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.",cellular response to type I interferon,biological_process
83090,GO:0071358,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.",cellular response to type III interferon,biological_process
83091,GO:0071359,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.",cellular response to dsRNA,biological_process
83092,GO:0071360,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.",cellular response to exogenous dsRNA,biological_process
83093,GO:0071361,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.",cellular response to ethanol,biological_process
83094,GO:0071362,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.",cellular response to ether,biological_process
83095,GO:0071363,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.",cellular response to growth factor stimulus,biological_process
83096,GO:0071364,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.",cellular response to epidermal growth factor stimulus,biological_process
83097,GO:0071365,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.",cellular response to auxin stimulus,biological_process
83098,GO:0071366,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.",cellular response to indolebutyric acid stimulus,biological_process
83099,GO:0071367,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.",cellular response to brassinosteroid stimulus,biological_process
83100,GO:0071368,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.",cellular response to cytokinin stimulus,biological_process
83101,GO:0071369,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.",cellular response to ethylene stimulus,biological_process
83102,GO:0071370,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.",cellular response to gibberellin stimulus,biological_process
83103,GO:0071371,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.",cellular response to gonadotropin stimulus,biological_process
83104,GO:0071372,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.",cellular response to follicle-stimulating hormone stimulus,biological_process
83105,GO:0071373,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.",cellular response to luteinizing hormone stimulus,biological_process
83106,GO:0071374,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.",cellular response to parathyroid hormone stimulus,biological_process
83107,GO:0071375,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.",cellular response to peptide hormone stimulus,biological_process
83108,GO:0071376,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.",cellular response to corticotropin-releasing hormone stimulus,biological_process
83109,GO:0071377,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.",cellular response to glucagon stimulus,biological_process
83110,GO:0071378,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.",cellular response to growth hormone stimulus,biological_process
83111,GO:0071379,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.",cellular response to prostaglandin stimulus,biological_process
83112,GO:0071380,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.",cellular response to prostaglandin E stimulus,biological_process
83113,GO:0071381,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.",cellular response to prostaglandin F stimulus,biological_process
83114,GO:0071382,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.",cellular response to prostaglandin I stimulus,biological_process
83115,GO:0071383,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.",cellular response to steroid hormone stimulus,biological_process
83116,GO:0071384,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior....",cellular response to corticosteroid stimulus,biological_process
83117,GO:0071385,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.",cellular response to glucocorticoid stimulus,biological_process
83118,GO:0071386,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.",cellular response to corticosterone stimulus,biological_process
83119,GO:0071387,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.",cellular response to cortisol stimulus,biological_process
83120,GO:0071388,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it ...",cellular response to cortisone stimulus,biological_process
83121,GO:0071389,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.",cellular response to mineralocorticoid stimulus,biological_process
83122,GO:0071390,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.",cellular response to ecdysone,biological_process
83123,GO:0071391,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.",cellular response to estrogen stimulus,biological_process
83124,GO:0071392,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.",cellular response to estradiol stimulus,biological_process
83125,GO:0071393,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.",cellular response to progesterone stimulus,biological_process
83126,GO:0071394,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.",cellular response to testosterone stimulus,biological_process
83127,GO:0071395,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.",cellular response to jasmonic acid stimulus,biological_process
83128,GO:0071396,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.",cellular response to lipid,biological_process
83129,GO:0071397,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.",cellular response to cholesterol,biological_process
83130,GO:0071398,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.",cellular response to fatty acid,biological_process
83131,GO:0071399,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.",cellular response to linoleic acid,biological_process
83132,GO:0071400,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.",cellular response to oleic acid,biological_process
83133,GO:0071401,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.",cellular response to triglyceride,biological_process
83134,GO:0071402,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.",cellular response to lipoprotein particle stimulus,biological_process
83135,GO:0071403,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.",cellular response to high density lipoprotein particle stimulus,biological_process
83136,GO:0071404,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.",cellular response to low-density lipoprotein particle stimulus,biological_process
83137,GO:0071405,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.",cellular response to methanol,biological_process
83138,GO:0071406,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.",cellular response to methylmercury,biological_process
83139,GO:0071408,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.",cellular response to cycloalkane,biological_process
83140,GO:0071409,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.",cellular response to cycloheximide,biological_process
83141,GO:0071410,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.",cellular response to cyclopentenone,biological_process
83142,GO:0071411,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.",cellular response to fluoxetine,biological_process
83143,GO:0071412,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.",cellular response to genistein,biological_process
83144,GO:0071413,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.",cellular response to hydroxyisoflavone,biological_process
83145,GO:0071414,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.",cellular response to methotrexate,biological_process
83146,GO:0071415,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.",cellular response to purine-containing compound,biological_process
83147,GO:0071416,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.",cellular response to tropane,biological_process
83148,GO:0071418,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.",cellular response to amine stimulus,biological_process
83149,GO:0071419,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.",cellular response to amphetamine,biological_process
83150,GO:0071420,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.",cellular response to histamine,biological_process
83151,GO:0071421,A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,manganese ion transmembrane transport,biological_process
83152,GO:0071422,The process in which succinate is transported across a membrane.,succinate transmembrane transport,biological_process
83153,GO:0071423,A process in which a malate ion is transported across a membrane.,malate transmembrane transport,biological_process
83154,GO:0071424,Catalysis of the reaction: a cytidine in rRNA + S-adenosyl-L-methionine = an N(4)-methylcytidine in rRNA + H+ + S-adenosyl-L-homocysteine.,rRNA (cytosine-N4-)-methyltransferase activity,molecular_function
83155,GO:0071425,The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.,hematopoietic stem cell proliferation,biological_process
83156,GO:0071433,A process of cell wall organization that results in the restoration of the cell wall following damage.,cell wall repair,biological_process
83157,GO:0071434,The directed movement of a motile cell in response to the presence of angiotensin.,cell chemotaxis to angiotensin,biological_process
83158,GO:0071439,"A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.",clathrin complex,cellular_component
83159,GO:0071443,Binding to DNA sequences encoding transfer RNA.,tDNA binding,molecular_function
83160,GO:0071444,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.",cellular response to pheromone,biological_process
83161,GO:0071446,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.",cellular response to salicylic acid stimulus,biological_process
83162,GO:0071447,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.",cellular response to hydroperoxide,biological_process
83163,GO:0071448,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.",cellular response to alkyl hydroperoxide,biological_process
83164,GO:0071449,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.",cellular response to lipid hydroperoxide,biological_process
83165,GO:0071450,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.",cellular response to oxygen radical,biological_process
83166,GO:0071451,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.",cellular response to superoxide,biological_process
83167,GO:0071452,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.",cellular response to singlet oxygen,biological_process
83168,GO:0071453,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.",cellular response to oxygen levels,biological_process
83169,GO:0071454,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.",cellular response to anoxia,biological_process
83170,GO:0071455,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.",cellular response to hyperoxia,biological_process
83171,GO:0071456,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.",cellular response to hypoxia,biological_process
83172,GO:0071457,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.",cellular response to ozone,biological_process
83173,GO:0071459,"Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.","protein localization to chromosome, centromeric region",biological_process
83174,GO:0071460,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.",cellular response to cell-matrix adhesion,biological_process
83175,GO:0071461,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.",cellular response to redox state,biological_process
83176,GO:0071462,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.",cellular response to water stimulus,biological_process
83177,GO:0071463,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.",cellular response to humidity,biological_process
83178,GO:0071464,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.",cellular response to hydrostatic pressure,biological_process
83179,GO:0071465,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.",cellular response to desiccation,biological_process
83180,GO:0071466,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",cellular response to xenobiotic stimulus,biological_process
83181,GO:0071467,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.",cellular response to pH,biological_process
83182,GO:0071468,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.",cellular response to acidic pH,biological_process
83183,GO:0071469,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.",cellular response to alkaline pH,biological_process
83184,GO:0071470,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.",cellular response to osmotic stress,biological_process
83185,GO:0071471,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.",cellular response to non-ionic osmotic stress,biological_process
83186,GO:0071472,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",cellular response to salt stress,biological_process
83187,GO:0071473,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.",cellular response to cation stress,biological_process
83188,GO:0071474,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.",cellular hyperosmotic response,biological_process
83189,GO:0071475,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",cellular hyperosmotic salinity response,biological_process
83190,GO:0071476,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.",cellular hypotonic response,biological_process
83191,GO:0071477,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.",cellular hypotonic salinity response,biological_process
83192,GO:0071478,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.",cellular response to radiation,biological_process
83193,GO:0071479,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.",cellular response to ionizing radiation,biological_process
83194,GO:0071480,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also th...",cellular response to gamma radiation,biological_process
83195,GO:0071481,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).",cellular response to X-ray,biological_process
83196,GO:0071482,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.",cellular response to light stimulus,biological_process
83197,GO:0071483,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.",cellular response to blue light,biological_process
83198,GO:0071484,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.",cellular response to light intensity,biological_process
83199,GO:0071485,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.",cellular response to absence of light,biological_process
83200,GO:0071486,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.",cellular response to high light intensity,biological_process
83201,GO:0071487,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.",cellular response to low light intensity stimulus,biological_process
83202,GO:0071488,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.",cellular response to very low light intensity stimulus,biological_process
83203,GO:0071489,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is trig...",cellular response to red or far red light,biological_process
83204,GO:0071490,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorpti...",cellular response to far red light,biological_process
83205,GO:0071491,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption ...",cellular response to red light,biological_process
83206,GO:0071492,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.",cellular response to UV-A,biological_process
83207,GO:0071493,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.",cellular response to UV-B,biological_process
83208,GO:0071494,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.",cellular response to UV-C,biological_process
83209,GO:0071495,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.",cellular response to endogenous stimulus,biological_process
83210,GO:0071496,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.",cellular response to external stimulus,biological_process
83211,GO:0071497,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.",cellular response to freezing,biological_process
83212,GO:0071498,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.",cellular response to fluid shear stress,biological_process
83213,GO:0071499,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.",cellular response to laminar fluid shear stress,biological_process
83214,GO:0071500,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.",cellular response to nitrosative stress,biological_process
83215,GO:0071501,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.",cellular response to sterol depletion,biological_process
83216,GO:0071502,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.",cellular response to temperature stimulus,biological_process
83217,GO:0071503,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.",response to heparin,biological_process
83218,GO:0071504,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.",cellular response to heparin,biological_process
83219,GO:0071505,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.",response to mycophenolic acid,biological_process
83220,GO:0071506,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.",cellular response to mycophenolic acid,biological_process
83221,GO:0071507,"A MAPK cascade containing at least the Fus3 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Fus3. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. This MAPK cascade is triggered by a pheromone activating its G protein-coupled receptor, and results in cellular responses that lead to conjugation with cellular fusion.",pheromone response MAPK cascade,biological_process
83222,GO:0071513,"A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.",phosphopantothenoylcysteine decarboxylase complex,cellular_component
83223,GO:0071514,"The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.",genomic imprinting,biological_process
83224,GO:0071515,"A genomic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.",mating-type locus imprinting,biological_process
83225,GO:0071518,"Catalysis of the reaction: (S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H+.",autoinducer-2 kinase activity,molecular_function
83226,GO:0071519,A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.,actomyosin contractile ring actin filament bundle assembly,biological_process
83227,GO:0071520,"A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.",actomyosin contractile ring assembly actin filament bundle convergence,biological_process
83228,GO:0071521,"A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signaling pathway.",Cdc42 GTPase complex,cellular_component
83229,GO:0071522,Catalysis of the reaction: (S)-2-ureidoglycine + H2O = (S)-ureidoglycolate + NH4+.,ureidoglycine aminohydrolase activity,molecular_function
83230,GO:0071524,The chemical reactions and pathways resulting in the formation of pyrrolysine.,pyrrolysine biosynthetic process,biological_process
83231,GO:0071526,The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.,semaphorin-plexin signaling pathway,biological_process
83232,GO:0071528,"The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.",tRNA re-export from nucleus,biological_process
83233,GO:0071529,"The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.",cementum mineralization,biological_process
83234,GO:0071532,"Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.",ankyrin repeat binding,molecular_function
83235,GO:0071535,Binding to a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.,RING-like zinc finger domain binding,molecular_function
83236,GO:0071539,"A process in which a protein is transported to, or maintained at, the centrosome.",protein localization to centrosome,biological_process
83237,GO:0071540,An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.,"eukaryotic translation initiation factor 3 complex, eIF3e",cellular_component
83238,GO:0071541,An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.,"eukaryotic translation initiation factor 3 complex, eIF3m",cellular_component
83239,GO:0071542,"The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.",dopaminergic neuron differentiation,biological_process
83240,GO:0071543,"The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.",diphosphoinositol polyphosphate metabolic process,biological_process
83241,GO:0071544,"The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.",diphosphoinositol polyphosphate catabolic process,biological_process
83242,GO:0071545,"The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.",inositol phosphate catabolic process,biological_process
83243,GO:0071546,"A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.",pi-body,cellular_component
83244,GO:0071547,"A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.",piP-body,cellular_component
83245,GO:0071548,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.",response to dexamethasone,biological_process
83246,GO:0071549,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.",cellular response to dexamethasone stimulus,biological_process
83247,GO:0071550,"A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.",death-inducing signaling complex assembly,biological_process
83248,GO:0071551,"Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.",RIP homotypic interaction motif binding,molecular_function
83249,GO:0071553,Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled pyrimidinergic nucleotide receptor activity,molecular_function
83250,GO:0071554,"A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.",cell wall organization or biogenesis,biological_process
83251,GO:0071555,"A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.",cell wall organization,biological_process
83252,GO:0071558,Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K27me2/H3K27me3 demethylase activity,molecular_function
83253,GO:0071559,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.",response to transforming growth factor beta,biological_process
83254,GO:0071560,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.",cellular response to transforming growth factor beta stimulus,biological_process
83255,GO:0071561,An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.,nucleus-vacuole junction,cellular_component
83256,GO:0071562,"The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway.",nucleus-vacuole junction assembly,biological_process
83257,GO:0071563,"A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.",Myo2p-Vac17p-Vac8p transport complex,cellular_component
83258,GO:0071564,"A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.",npBAF complex,cellular_component
83259,GO:0071565,"A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.",nBAF complex,cellular_component
83260,GO:0071566,"Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.",UFM1 activating enzyme activity,molecular_function
83261,GO:0071567,A thiol-dependent isopeptidase activity that cleaves UFM1 from a target protein to which it is conjugated.,deUFMylase activity,molecular_function
83262,GO:0071568,"Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.",UFM1 transferase activity,molecular_function
83263,GO:0071569,Covalent attachment of the ubiquitin-like protein UFM1 to another protein.,protein ufmylation,biological_process
83264,GO:0071570,"The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.",cement gland development,biological_process
83265,GO:0071573,"The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.",shelterin complex assembly,biological_process
83266,GO:0071574,"A process in which a protein is transported to, or maintained in, the medial cortex.",protein localization to medial cortex,biological_process
83267,GO:0071576,"Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.",tetrahydrodictyopterin binding,molecular_function
83268,GO:0071577,A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,zinc ion transmembrane transport,biological_process
83269,GO:0071578,"The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol.",zinc ion import across plasma membrane,biological_process
83270,GO:0071579,"Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of zinc ion transport,biological_process
83271,GO:0071580,"Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.",regulation of zinc ion transmembrane transport,biological_process
83272,GO:0071581,"Any process that modulates the frequency, rate or extent of zinc ion import.",regulation of zinc ion transmembrane import,biological_process
83273,GO:0071582,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of zinc ion transport,biological_process
83274,GO:0071583,"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.",negative regulation of zinc ion transmembrane transport,biological_process
83275,GO:0071584,"Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.",negative regulation of zinc ion transmembrane import,biological_process
83276,GO:0071585,Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.,detoxification of cadmium ion,biological_process
83277,GO:0071586,"The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.",CAAX-box protein processing,biological_process
83278,GO:0071588,The series of molecular signals mediated by the detection of hydrogen peroxide (H2O2).,hydrogen peroxide mediated signaling pathway,biological_process
83279,GO:0071589,"The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.",pyridine nucleoside biosynthetic process,biological_process
83280,GO:0071590,"The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.",nicotinamide riboside biosynthetic process,biological_process
83281,GO:0071592,"The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.",nicotinic acid riboside biosynthetic process,biological_process
83282,GO:0071593,The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules.,lymphocyte aggregation,biological_process
83283,GO:0071594,The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.,thymocyte aggregation,biological_process
83284,GO:0071595,"A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.",Nem1-Spo7 phosphatase complex,cellular_component
83285,GO:0071596,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.",ubiquitin-dependent protein catabolic process via the N-end rule pathway,biological_process
83286,GO:0071597,"Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.",cellular birth scar,cellular_component
83287,GO:0071598,"A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.",neuronal ribonucleoprotein granule,cellular_component
83288,GO:0071599,"The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.",otic vesicle development,biological_process
83289,GO:0071600,The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.,otic vesicle morphogenesis,biological_process
83290,GO:0071601,"A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.",sphere organelle,cellular_component
83291,GO:0071602,"The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.",phytosphingosine biosynthetic process,biological_process
83292,GO:0071603,The attachment of an endothelial cell to another endothelial cell via adhesion molecules.,endothelial cell-cell adhesion,biological_process
83293,GO:0071604,"The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.",transforming growth factor beta production,biological_process
83294,GO:0071605,"The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",monocyte chemotactic protein-1 production,biological_process
83295,GO:0071606,"The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 4 production,biological_process
83296,GO:0071607,"The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",macrophage inflammatory protein-1 gamma production,biological_process
83297,GO:0071608,"The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",macrophage inflammatory protein-1 alpha production,biological_process
83298,GO:0071609,"The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 5 production,biological_process
83299,GO:0071610,"The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 1 production,biological_process
83300,GO:0071611,"The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",granulocyte colony-stimulating factor production,biological_process
83301,GO:0071612,"The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",IP-10 production,biological_process
83302,GO:0071613,"The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",granzyme B production,biological_process
83303,GO:0071614,Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.,linoleic acid epoxygenase activity,molecular_function
83304,GO:0071616,"The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.",acyl-CoA biosynthetic process,biological_process
83305,GO:0071617,Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.,lysophospholipid acyltransferase activity,molecular_function
83306,GO:0071618,Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.,lysophosphatidylethanolamine acyltransferase activity,molecular_function
83307,GO:0071621,The movement of a granulocyte in response to an external stimulus.,granulocyte chemotaxis,biological_process
83308,GO:0071622,"Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.",regulation of granulocyte chemotaxis,biological_process
83309,GO:0071623,"Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.",negative regulation of granulocyte chemotaxis,biological_process
83310,GO:0071624,"Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.",positive regulation of granulocyte chemotaxis,biological_process
83311,GO:0071625,The behavior in which an organism produces sounds by a mechanism involving its respiratory system.,vocalization behavior,biological_process
83312,GO:0071626,The process of biting and mashing food with the teeth prior to swallowing.,mastication,biological_process
83313,GO:0071629,"The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.",cytoplasm protein quality control by the ubiquitin-proteasome system,biological_process
83314,GO:0071630,"A protein quality control pathway that results in the breakdown of misfolded, damaged or unassembled proteins via a mechanism in which the proteins are ubiquitinated, and then targeted to nuclear proteasomes for degradation.",nuclear protein quality control by the ubiquitin-proteasome system,biological_process
83315,GO:0071631,"The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types.",mating pheromone secretion involved in positive regulation of conjugation with cellular fusion,biological_process
83316,GO:0071632,"Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.",optomotor response,biological_process
83317,GO:0071634,"Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.",regulation of transforming growth factor beta production,biological_process
83318,GO:0071635,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.",negative regulation of transforming growth factor beta production,biological_process
83319,GO:0071636,"Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.",positive regulation of transforming growth factor beta production,biological_process
83320,GO:0071637,"Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.",regulation of monocyte chemotactic protein-1 production,biological_process
83321,GO:0071638,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.",negative regulation of monocyte chemotactic protein-1 production,biological_process
83322,GO:0071639,"Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.",positive regulation of monocyte chemotactic protein-1 production,biological_process
83323,GO:0071640,"Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.",regulation of macrophage inflammatory protein 1 alpha production,biological_process
83324,GO:0071641,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.",negative regulation of macrophage inflammatory protein 1 alpha production,biological_process
83325,GO:0071642,"Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.",positive regulation of macrophage inflammatory protein 1 alpha production,biological_process
83326,GO:0071643,"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.",regulation of chemokine (C-C motif) ligand 4 production,biological_process
83327,GO:0071644,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.",negative regulation of chemokine (C-C motif) ligand 4 production,biological_process
83328,GO:0071645,"Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.",positive regulation of chemokine (C-C motif) ligand 4 production,biological_process
83329,GO:0071646,"Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.",regulation of macrophage inflammatory protein-1 gamma production,biological_process
83330,GO:0071647,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.",negative regulation of macrophage inflammatory protein-1 gamma production,biological_process
83331,GO:0071648,"Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.",positive regulation of macrophage inflammatory protein-1 gamma production,biological_process
83332,GO:0071649,"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.",regulation of chemokine (C-C motif) ligand 5 production,biological_process
83333,GO:0071650,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.",negative regulation of chemokine (C-C motif) ligand 5 production,biological_process
83334,GO:0071651,"Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.",positive regulation of chemokine (C-C motif) ligand 5 production,biological_process
83335,GO:0071652,"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.",regulation of chemokine (C-C motif) ligand 1 production,biological_process
83336,GO:0071653,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.",negative regulation of chemokine (C-C motif) ligand 1 production,biological_process
83337,GO:0071654,"Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.",positive regulation of chemokine (C-C motif) ligand 1 production,biological_process
83338,GO:0071655,"Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.",regulation of granulocyte colony-stimulating factor production,biological_process
83339,GO:0071656,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.",negative regulation of granulocyte colony-stimulating factor production,biological_process
83340,GO:0071657,"Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.",positive regulation of granulocyte colony-stimulating factor production,biological_process
83341,GO:0071658,"Any process that modulates the frequency, rate, or extent of production of IP-10.",regulation of IP-10 production,biological_process
83342,GO:0071659,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.",negative regulation of IP-10 production,biological_process
83343,GO:0071660,"Any process that activates or increases the frequency, rate, or extent of production of IP-10.",positive regulation of IP-10 production,biological_process
83344,GO:0071661,"Any process that modulates the frequency, rate, or extent of production of granzyme B.",regulation of granzyme B production,biological_process
83345,GO:0071662,"Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.",negative regulation of granzyme B production,biological_process
83346,GO:0071663,"Any process that activates or increases the frequency, rate, or extent of production of granzyme B.",positive regulation of granzyme B production,biological_process
83347,GO:0071664,"A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.",catenin-TCF7L2 complex,cellular_component
83348,GO:0071665,"A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.",gamma-catenin-TCF7L2 complex,cellular_component
83349,GO:0071666,"A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.",Slit-Robo signaling complex,cellular_component
83350,GO:0071667,Binding to a RNA/DNA hybrid.,DNA/RNA hybrid binding,molecular_function
83351,GO:0071668,"The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.",plant-type cell wall assembly,biological_process
83352,GO:0071669,"A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.",plant-type cell wall organization or biogenesis,biological_process
83353,GO:0071670,The directed movement of a smooth muscle cell in response to an external stimulus.,smooth muscle cell chemotaxis,biological_process
83354,GO:0071671,"Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.",regulation of smooth muscle cell chemotaxis,biological_process
83355,GO:0071672,"Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.",negative regulation of smooth muscle cell chemotaxis,biological_process
83356,GO:0071673,"Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.",positive regulation of smooth muscle cell chemotaxis,biological_process
83357,GO:0071674,The movement of a mononuclear cell within or between different tissues and organs of the body.,mononuclear cell migration,biological_process
83358,GO:0071675,"Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.",regulation of mononuclear cell migration,biological_process
83359,GO:0071676,"Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.",negative regulation of mononuclear cell migration,biological_process
83360,GO:0071677,"Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.",positive regulation of mononuclear cell migration,biological_process
83361,GO:0071678,The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.,olfactory bulb axon guidance,biological_process
83362,GO:0071679,The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.,commissural neuron axon guidance,biological_process
83363,GO:0071680,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.",response to indole-3-methanol,biological_process
83364,GO:0071681,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.",cellular response to indole-3-methanol,biological_process
83365,GO:0071682,The volume enclosed by the membrane of an endocytic vesicle.,endocytic vesicle lumen,cellular_component
83366,GO:0071683,"A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.",sensory dendrite,cellular_component
83367,GO:0071684,The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.,organism emergence from protective structure,biological_process
83368,GO:0071685,"An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.",NADH dehydrogenase complex (plastoquinone),cellular_component
83369,GO:0071688,"The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.",striated muscle myosin thick filament assembly,biological_process
83370,GO:0071689,"The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.",muscle thin filament assembly,biological_process
83371,GO:0071690,"The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.",cardiac muscle myosin thick filament assembly,biological_process
83372,GO:0071691,"The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.",cardiac muscle thin filament assembly,biological_process
83373,GO:0071692,"Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.",protein localization to extracellular region,biological_process
83374,GO:0071693,"The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.",protein transport within extracellular region,biological_process
83375,GO:0071694,Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.,maintenance of protein location in extracellular region,biological_process
83376,GO:0071695,"A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.",anatomical structure maturation,biological_process
83377,GO:0071696,The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.,ectodermal placode development,biological_process
83378,GO:0071697,The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.,ectodermal placode morphogenesis,biological_process
83379,GO:0071698,The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.,olfactory placode development,biological_process
83380,GO:0071699,The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.,olfactory placode morphogenesis,biological_process
83381,GO:0071700,"A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.",olfactory placode maturation,biological_process
83382,GO:0071705,"The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nitrogen compound transport,biological_process
83383,GO:0071706,"The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",tumor necrosis factor superfamily cytokine production,biological_process
83384,GO:0071707,"The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).",immunoglobulin heavy chain V-D-J recombination,biological_process
83385,GO:0071708,The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).,immunoglobulin light chain V-J recombination,biological_process
83386,GO:0071709,"The aggregation, arrangement and bonding together of a set of components to form a membrane.",membrane assembly,biological_process
83387,GO:0071710,The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.,membrane macromolecule biosynthetic process,biological_process
83388,GO:0071711,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.",basement membrane organization,biological_process
83389,GO:0071713,Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.,para-aminobenzoyl-glutamate hydrolase activity,molecular_function
83390,GO:0071714,Enables the transfer of icosanoids from one side of a membrane to the other.,icosanoid transmembrane transporter activity,molecular_function
83391,GO:0071715,"The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.",icosanoid transport,biological_process
83392,GO:0071716,"The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.",leukotriene transport,biological_process
83393,GO:0071717,"The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.",thromboxane transport,biological_process
83394,GO:0071718,"The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.",sodium-independent icosanoid transport,biological_process
83395,GO:0071719,"The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.",sodium-independent leukotriene transport,biological_process
83396,GO:0071720,"The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sodium-independent prostaglandin transport,biological_process
83397,GO:0071721,"The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.",sodium-independent thromboxane transport,biological_process
83398,GO:0071722,"Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.",detoxification of arsenic-containing substance,biological_process
83399,GO:0071723,"Binding to a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids.",lipopeptide binding,molecular_function
83400,GO:0071724,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.",response to diacyl bacterial lipopeptide,biological_process
83401,GO:0071725,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.",response to triacyl bacterial lipopeptide,biological_process
83402,GO:0071726,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.",cellular response to diacyl bacterial lipopeptide,biological_process
83403,GO:0071727,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.",cellular response to triacyl bacterial lipopeptide,biological_process
83404,GO:0071728,"The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.",beak development,biological_process
83405,GO:0071729,"The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.",beak morphogenesis,biological_process
83406,GO:0071730,"The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.",beak formation,biological_process
83407,GO:0071731,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.",response to nitric oxide,biological_process
83408,GO:0071732,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.",cellular response to nitric oxide,biological_process
83409,GO:0071735,"A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgG immunoglobulin complex,cellular_component
83410,GO:0071736,"A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.","IgG immunoglobulin complex, circulating",cellular_component
83411,GO:0071737,"An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",IgG B cell receptor complex,cellular_component
83412,GO:0071738,"A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgD immunoglobulin complex,cellular_component
83413,GO:0071739,"A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.","IgD immunoglobulin complex, circulating",cellular_component
83414,GO:0071740,"An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",IgD B cell receptor complex,cellular_component
83415,GO:0071741,"A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.","IgD immunoglobulin complex, GPI-anchored",cellular_component
83416,GO:0071742,"A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgE immunoglobulin complex,cellular_component
83417,GO:0071743,"A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.","IgE immunoglobulin complex, circulating",cellular_component
83418,GO:0071744,"An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",IgE B cell receptor complex,cellular_component
83419,GO:0071745,"A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgA immunoglobulin complex,cellular_component
83420,GO:0071746,"A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.","IgA immunoglobulin complex, circulating",cellular_component
83421,GO:0071747,"An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",IgA B cell receptor complex,cellular_component
83422,GO:0071748,"A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",monomeric IgA immunoglobulin complex,cellular_component
83423,GO:0071749,"A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal a...",polymeric IgA immunoglobulin complex,cellular_component
83424,GO:0071750,"A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other t...",dimeric IgA immunoglobulin complex,cellular_component
83425,GO:0071751,"A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.",secretory IgA immunoglobulin complex,cellular_component
83426,GO:0071752,A dimeric form of secretory IgA immunoglobulin complex.,secretory dimeric IgA immunoglobulin complex,cellular_component
83427,GO:0071753,"A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgM immunoglobulin complex,cellular_component
83428,GO:0071754,"A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.","IgM immunoglobulin complex, circulating",cellular_component
83429,GO:0071755,"An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.",IgM B cell receptor complex,cellular_component
83430,GO:0071756,A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.,pentameric IgM immunoglobulin complex,cellular_component
83431,GO:0071757,A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.,hexameric IgM immunoglobulin complex,cellular_component
83432,GO:0071758,"A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgW immunoglobulin complex,cellular_component
83433,GO:0071759,"A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgX immunoglobulin complex,cellular_component
83434,GO:0071760,"A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.",IgY immunoglobulin complex,cellular_component
83435,GO:0071761,"A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.",IgZ immunoglobulin complex,cellular_component
83436,GO:0071762,A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.,heavy chain immunoglobulin complex,cellular_component
83437,GO:0071763,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.",nuclear membrane organization,biological_process
83438,GO:0071764,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.",nuclear outer membrane organization,biological_process
83439,GO:0071765,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.",nuclear inner membrane organization,biological_process
83440,GO:0071766,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.",Actinobacterium-type cell wall biogenesis,biological_process
83441,GO:0071768,"The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.",mycolic acid biosynthetic process,biological_process
83442,GO:0071769,"The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.",mycolate cell wall layer assembly,biological_process
83443,GO:0071770,"The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.",DIM/DIP cell wall layer assembly,biological_process
83444,GO:0071771,Catalysis of the reaction: a long-chain fatty aldehyde + H+ + 2 NADPH + O2 = a long-chain alkane + formate + H2O + 2 NADP+.,aldehyde oxygenase (deformylating) activity,molecular_function
83445,GO:0071772,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.",response to BMP,biological_process
83446,GO:0071773,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.",cellular response to BMP stimulus,biological_process
83447,GO:0071774,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.",response to fibroblast growth factor,biological_process
83448,GO:0071781,"A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells.",endoplasmic reticulum cisternal network,cellular_component
83449,GO:0071782,A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.,endoplasmic reticulum tubular network,cellular_component
83450,GO:0071783,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.",endoplasmic reticulum cisternal network organization,biological_process
83451,GO:0071784,"The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.",endoplasmic reticulum cisternal network assembly,biological_process
83452,GO:0071785,The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.,endoplasmic reticulum cisternal network maintenance,biological_process
83453,GO:0071786,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.",endoplasmic reticulum tubular network organization,biological_process
83454,GO:0071787,"The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.",endoplasmic reticulum tubular network formation,biological_process
83455,GO:0071788,The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.,endoplasmic reticulum tubular network maintenance,biological_process
83456,GO:0071791,Binding to chemokine (C-C motif) ligand 5.,chemokine (C-C motif) ligand 5 binding,molecular_function
83457,GO:0071793,"The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.",bacillithiol biosynthetic process,biological_process
83458,GO:0071794,"Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.",CAP-Gly domain binding,molecular_function
83459,GO:0071795,Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.,K11-linked polyubiquitin modification-dependent protein binding,molecular_function
83460,GO:0071796,Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.,K6-linked polyubiquitin modification-dependent protein binding,molecular_function
83461,GO:0071797,"A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.",LUBAC complex,cellular_component
83462,GO:0071798,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.",response to prostaglandin D,biological_process
83463,GO:0071799,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.",cellular response to prostaglandin D stimulus,biological_process
83464,GO:0071800,"The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.",podosome assembly,biological_process
83465,GO:0071801,"Any process that modulates the frequency, rate or extent of podosome assembly.",regulation of podosome assembly,biological_process
83466,GO:0071802,"Any process that stops, prevents or reduces the rate or extent of podosome assembly.",negative regulation of podosome assembly,biological_process
83467,GO:0071803,Any process that activates or increases the rate or extent of podosome assembly.,positive regulation of podosome assembly,biological_process
83468,GO:0071805,A process in which a potassium ion is transported from one side of a membrane to the other.,potassium ion transmembrane transport,biological_process
83469,GO:0071806,The process in which a protein is transported across a membrane.,protein transmembrane transport,biological_process
83470,GO:0071807,A replication fork arrest process that contributes to the termination of DNA replication.,replication fork arrest involved in DNA replication termination,biological_process
83471,GO:0071808,An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).,satellite fibril,cellular_component
83472,GO:0071809,"Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",regulation of fever generation by regulation of prostaglandin biosynthesis,biological_process
83473,GO:0071810,"Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.",regulation of fever generation by regulation of prostaglandin secretion,biological_process
83474,GO:0071811,"Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.",positive regulation of fever generation by positive regulation of prostaglandin biosynthesis,biological_process
83475,GO:0071812,"Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.",positive regulation of fever generation by positive regulation of prostaglandin secretion,biological_process
83476,GO:0071813,"Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.",lipoprotein particle binding,molecular_function
83477,GO:0071814,"Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.",protein-lipid complex binding,molecular_function
83478,GO:0071815,"Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.",intermediate-density lipoprotein particle binding,molecular_function
83479,GO:0071816,"A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.",tail-anchored membrane protein insertion into ER membrane,biological_process
83480,GO:0071817,"A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.",MMXD complex,cellular_component
83481,GO:0071818,"A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.",BAT3 complex,cellular_component
83482,GO:0071819,"A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.",DUBm complex,cellular_component
83483,GO:0071820,"Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.",N-box binding,molecular_function
83484,GO:0071821,"A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.",FANCM-MHF complex,cellular_component
83485,GO:0071823,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.",protein-carbohydrate complex subunit organization,biological_process
83486,GO:0071824,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.",protein-DNA complex organization,biological_process
83487,GO:0071825,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.",protein-lipid complex organization,biological_process
83488,GO:0071826,"Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.",protein-RNA complex organization,biological_process
83489,GO:0071827,"A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.",plasma lipoprotein particle organization,biological_process
83490,GO:0071828,"The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.",apolipoprotein E recycling,biological_process
83491,GO:0071829,The disaggregation of a plasma lipoprotein particle into its constituent components.,plasma lipoprotein particle disassembly,biological_process
83492,GO:0071830,The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,triglyceride-rich lipoprotein particle clearance,biological_process
83493,GO:0071831,The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,intermediate-density lipoprotein particle clearance,biological_process
83494,GO:0071834,"The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.",mating pheromone secretion,biological_process
83495,GO:0071836,"The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.",nectar secretion,biological_process
83496,GO:0071837,"Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.",HMG box domain binding,molecular_function
83497,GO:0071838,"The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.",cell proliferation in bone marrow,biological_process
83498,GO:0071839,The apoptotic process in cells in the bone marrow.,apoptotic process in bone marrow cell,biological_process
83499,GO:0071840,"A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.",cellular component organization or biogenesis,biological_process
83500,GO:0071846,An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.,actin filament debranching,biological_process
83501,GO:0071852,"A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.",fungal-type cell wall organization or biogenesis,biological_process
83502,GO:0071853,A cellular process that results in the breakdown of a fungal-type cell wall.,fungal-type cell wall disassembly,biological_process
83503,GO:0071855,Binding to a neuropeptide receptor.,neuropeptide receptor binding,molecular_function
83504,GO:0071857,Binding to a beta-endorphin receptor.,beta-endorphin receptor binding,molecular_function
83505,GO:0071858,Binding to a corazonin receptor.,corazonin receptor binding,molecular_function
83506,GO:0071859,Binding to a neuropeptide F receptor.,neuropeptide F receptor binding,molecular_function
83507,GO:0071860,Binding to a proctolin receptor.,proctolin receptor binding,molecular_function
83508,GO:0071861,Binding to a tachykinin receptor.,tachykinin receptor binding,molecular_function
83509,GO:0071863,"A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.",regulation of cell proliferation in bone marrow,biological_process
83510,GO:0071864,"A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.",positive regulation of cell proliferation in bone marrow,biological_process
83511,GO:0071865,Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.,regulation of apoptotic process in bone marrow cell,biological_process
83512,GO:0071866,"Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.",negative regulation of apoptotic process in bone marrow cell,biological_process
83513,GO:0071867,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.",response to monoamine,biological_process
83514,GO:0071868,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.",cellular response to monoamine stimulus,biological_process
83515,GO:0071869,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.",response to catecholamine,biological_process
83516,GO:0071870,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.",cellular response to catecholamine stimulus,biological_process
83517,GO:0071871,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.",response to epinephrine,biological_process
83518,GO:0071872,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.",cellular response to epinephrine stimulus,biological_process
83519,GO:0071873,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.",response to norepinephrine,biological_process
83520,GO:0071874,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.",cellular response to norepinephrine stimulus,biological_process
83521,GO:0071875,"A G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",adrenergic receptor signaling pathway,biological_process
83522,GO:0071877,"Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.",regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway,biological_process
83523,GO:0071878,"Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.",negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway,biological_process
83524,GO:0071879,"Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.",positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway,biological_process
83525,GO:0071880,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating adrenergic receptor signaling pathway,biological_process
83526,GO:0071881,"An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor, and ending with the regulation of a downstream cellular process.",adenylate cyclase-inhibiting adrenergic receptor signaling pathway,biological_process
83527,GO:0071882,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating adrenergic receptor signaling pathway,biological_process
83528,GO:0071883,The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.,MAPK-activating adrenergic receptor signaling pathway,biological_process
83529,GO:0071885,"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.",N-terminal protein N-methyltransferase activity,molecular_function
83530,GO:0071886,"Binding to the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.","1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding",molecular_function
83531,GO:0071887,"Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.",leukocyte apoptotic process,biological_process
83532,GO:0071888,"Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.",macrophage apoptotic process,biological_process
83533,GO:0071889,"Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided ...",14-3-3 protein binding,molecular_function
83534,GO:0071890,Binding to bicarbonate ions (CHO3-).,bicarbonate binding,molecular_function
83535,GO:0071892,"A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.",thrombocyte activation,biological_process
83536,GO:0071895,"The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.",odontoblast differentiation,biological_process
83537,GO:0071896,"Any process in which a protein is transported to, and/or maintained at the adherens junction.",protein localization to adherens junction,biological_process
83538,GO:0071897,The biosynthetic process resulting in the formation of DNA.,DNA biosynthetic process,biological_process
83539,GO:0071900,"Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.",regulation of protein serine/threonine kinase activity,biological_process
83540,GO:0071901,"Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.",negative regulation of protein serine/threonine kinase activity,biological_process
83541,GO:0071902,"Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.",positive regulation of protein serine/threonine kinase activity,biological_process
83542,GO:0071906,"Binding to a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.",CRD domain binding,molecular_function
83543,GO:0071907,Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.,determination of digestive tract left/right asymmetry,biological_process
83544,GO:0071908,Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.,determination of intestine left/right asymmetry,biological_process
83545,GO:0071909,Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.,determination of stomach left/right asymmetry,biological_process
83546,GO:0071910,Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.,determination of liver left/right asymmetry,biological_process
83547,GO:0071911,Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.,synchronous neurotransmitter secretion,biological_process
83548,GO:0071912,Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.,asynchronous neurotransmitter secretion,biological_process
83549,GO:0071913,"Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.",citrate secondary active transmembrane transporter activity,molecular_function
83550,GO:0071914,"An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not kn...",prominosome,cellular_component
83551,GO:0071916,Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.,dipeptide transmembrane transporter activity,molecular_function
83552,GO:0071917,Enables the transfer of a triose phosphate from one side of a membrane to the other.,triose-phosphate transmembrane transporter activity,molecular_function
83553,GO:0071918,"The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.",urea transmembrane transport,biological_process
83554,GO:0071919,"A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.",G-quadruplex DNA formation,biological_process
83555,GO:0071920,"A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.",cleavage body,cellular_component
83556,GO:0071924,"The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 22 production,biological_process
83557,GO:0071925,"The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",thymic stromal lymphopoietin production,biological_process
83558,GO:0071926,"The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.",endocannabinoid signaling pathway,biological_process
83559,GO:0071927,The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.,octopamine signaling pathway,biological_process
83560,GO:0071928,The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.,tyramine signaling pathway,biological_process
83561,GO:0071929,The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.,alpha-tubulin acetylation,biological_process
83562,GO:0071932,"Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.",replication fork reversal,biological_process
83563,GO:0071933,"Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).",Arp2/3 complex binding,molecular_function
83564,GO:0071934,"The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.",thiamine transmembrane transport,biological_process
83565,GO:0071938,"The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.",vitamin A transport,biological_process
83566,GO:0071939,"The directed movement of vitamin A from outside of a cell, across the plasma membrane and into the cytosol. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.",vitamin A import into cell,biological_process
83567,GO:0071940,"The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.",fungal-type cell wall assembly,biological_process
83568,GO:0071941,"A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.",nitrogen cycle metabolic process,biological_process
83569,GO:0071942,"A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.",XPC complex,cellular_component
83570,GO:0071943,A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.,Myc-Max complex,cellular_component
83571,GO:0071944,"The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.",cell periphery,cellular_component
83572,GO:0071945,"A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.",regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed,biological_process
83573,GO:0071946,"A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.",cis-acting DNA replication termination,biological_process
83574,GO:0071947,The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.,protein deubiquitination involved in ubiquitin-dependent protein catabolic process,biological_process
83575,GO:0071948,"B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.",activation-induced B cell apoptotic process,biological_process
83576,GO:0071949,"Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.",FAD binding,molecular_function
83577,GO:0071950,"Binding to the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.",FADH2 binding,molecular_function
83578,GO:0071951,The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).,conversion of methionyl-tRNA to N-formyl-methionyl-tRNA,biological_process
83579,GO:0071952,The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.,conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA,biological_process
83580,GO:0071953,"An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.",elastic fiber,cellular_component
83581,GO:0071954,"The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 11 production,biological_process
83582,GO:0071955,The directed movement of substances from recycling endosomes to the Golgi.,recycling endosome to Golgi transport,biological_process
83583,GO:0071957,"The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.",old mitotic spindle pole body,cellular_component
83584,GO:0071958,"The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.",new mitotic spindle pole body,cellular_component
83585,GO:0071959,"The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.","maintenance of mitotic sister chromatid cohesion, arms",biological_process
83586,GO:0071960,"The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.","maintenance of mitotic sister chromatid cohesion, centromeric",biological_process
83587,GO:0071961,The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.,"mitotic sister chromatid cohesion, arms",biological_process
83588,GO:0071962,The cell cycle process in which centromeres of sister chromatids are joined during mitosis.,"mitotic sister chromatid cohesion, centromeric",biological_process
83589,GO:0071963,"Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.",establishment or maintenance of cell polarity regulating cell shape,biological_process
83590,GO:0071964,Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.,establishment of cell polarity regulating cell shape,biological_process
83591,GO:0071965,"Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.",multicellular organismal locomotion,biological_process
83592,GO:0071966,The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.,fungal-type cell wall polysaccharide metabolic process,biological_process
83593,GO:0071967,Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.,lipopolysaccharide core heptosyltransferase activity,molecular_function
83594,GO:0071968,Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.,lipid A-core heptosyltransferase activity,molecular_function
83595,GO:0071969,"The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.",fungal-type cell wall (1->3)-beta-D-glucan metabolic process,biological_process
83596,GO:0071970,"The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.",fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process,biological_process
83597,GO:0071971,"The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.",extracellular exosome assembly,biological_process
83598,GO:0071972,"Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.","peptidoglycan L,D-transpeptidase activity",molecular_function
83599,GO:0071973,Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.,bacterial-type flagellum-dependent cell motility,biological_process
83600,GO:0071975,Cell motility that results in the smooth movement of a cell through a liquid medium.,cell swimming,biological_process
83601,GO:0071976,Cell motility that results in the smooth movement of a cell along a solid surface.,cell gliding,biological_process
83602,GO:0071977,Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.,bacterial-type flagellum-dependent swimming motility,biological_process
83603,GO:0071978,Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.,bacterial-type flagellum-dependent swarming motility,biological_process
83604,GO:0071979,"Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.",cytoskeleton-mediated cell swimming,biological_process
83605,GO:0071980,Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.,cell surface adhesin-mediated gliding motility,biological_process
83606,GO:0071981,"The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic ...",exit from diapause,biological_process
83607,GO:0071982,"The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun...",maintenance of diapause,biological_process
83608,GO:0071983,"The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",exit from reproductive diapause,biological_process
83609,GO:0071984,"The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.",maintenance of reproductive diapause,biological_process
83610,GO:0071985,"A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.",multivesicular body sorting pathway,biological_process
83611,GO:0071986,"A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signaling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no...",Ragulator complex,cellular_component
83612,GO:0071987,"Binding to a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.",WD40-repeat domain binding,molecular_function
83613,GO:0071988,"A process in which a protein is transported to, or maintained at, the spindle pole body.",protein localization to spindle pole body,biological_process
83614,GO:0071989,The directed movement of a protein to a specific location at the spindle pole body.,establishment of protein localization to spindle pole body,biological_process
83615,GO:0071990,"Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.",maintenance of protein location to spindle pole body,biological_process
83616,GO:0071993,"The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.",phytochelatin transport,biological_process
83617,GO:0071994,"The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.",phytochelatin transmembrane transport,biological_process
83618,GO:0071995,"The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.",phytochelatin import into vacuole,biological_process
83619,GO:0071996,The directed movement of glutathione into the vacuole across the vacuolar membrane.,glutathione transmembrane import into vacuole,biological_process
83620,GO:0071998,A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.,ascospore release from ascus,biological_process
83621,GO:0072001,"The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.",renal system development,biological_process
83622,GO:0072002,"The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.",Malpighian tubule development,biological_process
83623,GO:0072003,The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.,kidney rudiment formation,biological_process
83624,GO:0072004,The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.,kidney field specification,biological_process
83625,GO:0072005,The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,maintenance of kidney identity,biological_process
83626,GO:0072006,"The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.",nephron development,biological_process
83627,GO:0072007,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.,mesangial cell differentiation,biological_process
83628,GO:0072008,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.,glomerular mesangial cell differentiation,biological_process
83629,GO:0072009,"The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.",nephron epithelium development,biological_process
83630,GO:0072010,"The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epith...",glomerular epithelium development,biological_process
83631,GO:0072011,"The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.",glomerular endothelium development,biological_process
83632,GO:0072012,The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.,glomerulus vasculature development,biological_process
83633,GO:0072013,"The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.",glomus development,biological_process
83634,GO:0072014,"The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.",proximal tubule development,biological_process
83635,GO:0072015,"The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.",podocyte development,biological_process
83636,GO:0072016,"The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.",glomerular parietal epithelial cell development,biological_process
83637,GO:0072017,"The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.",distal tubule development,biological_process
83638,GO:0072019,"The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.",proximal convoluted tubule development,biological_process
83639,GO:0072020,"The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.",proximal straight tubule development,biological_process
83640,GO:0072021,"The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.",ascending thin limb development,biological_process
83641,GO:0072022,"The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.",descending thin limb development,biological_process
83642,GO:0072023,"The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.",thick ascending limb development,biological_process
83643,GO:0072024,"The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.",macula densa development,biological_process
83644,GO:0072025,"The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.",distal convoluted tubule development,biological_process
83645,GO:0072027,"The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.",connecting tubule development,biological_process
83646,GO:0072028,The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.,nephron morphogenesis,biological_process
83647,GO:0072029,"The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.",long nephron development,biological_process
83648,GO:0072030,"The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.",short nephron development,biological_process
83649,GO:0072031,"The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.",proximal convoluted tubule segment 1 development,biological_process
83650,GO:0072032,"The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.",proximal convoluted tubule segment 2 development,biological_process
83651,GO:0072033,"The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.",renal vesicle formation,biological_process
83652,GO:0072034,Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.,renal vesicle induction,biological_process
83653,GO:0072035,"The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.",pre-tubular aggregate formation,biological_process
83654,GO:0072038,The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.,mesenchymal stem cell maintenance involved in nephron morphogenesis,biological_process
83655,GO:0072040,Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.,negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis,biological_process
83656,GO:0072043,"Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.",regulation of pre-tubular aggregate formation by cell-cell signaling,biological_process
83657,GO:0072044,"The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.",collecting duct development,biological_process
83658,GO:0072045,The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.,convergent extension involved in nephron morphogenesis,biological_process
83659,GO:0072046,Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.,establishment of planar polarity involved in nephron morphogenesis,biological_process
83660,GO:0072047,The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).,proximal/distal pattern formation involved in nephron development,biological_process
83661,GO:0072048,Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.,renal system pattern specification,biological_process
83662,GO:0072049,The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.,comma-shaped body morphogenesis,biological_process
83663,GO:0072050,The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.,S-shaped body morphogenesis,biological_process
83664,GO:0072051,"The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.",juxtaglomerular apparatus development,biological_process
83665,GO:0072052,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.,juxtaglomerulus cell differentiation,biological_process
83666,GO:0072053,"The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.",renal inner medulla development,biological_process
83667,GO:0072054,"The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.",renal outer medulla development,biological_process
83668,GO:0072055,"The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.",renal cortex development,biological_process
83669,GO:0072056,"The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.",pyramid development,biological_process
83670,GO:0072057,"The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.",inner stripe development,biological_process
83671,GO:0072058,"The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.",outer stripe development,biological_process
83672,GO:0072059,"The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.",cortical collecting duct development,biological_process
83673,GO:0072060,"The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.",outer medullary collecting duct development,biological_process
83674,GO:0072061,"The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.",inner medullary collecting duct development,biological_process
83675,GO:0072062,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.,proximal convoluted tubule segment 1 cell differentiation,biological_process
83676,GO:0072063,"The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.",short descending thin limb development,biological_process
83677,GO:0072064,"The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.",long descending thin limb development,biological_process
83678,GO:0072065,"The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.",long descending thin limb bend development,biological_process
83679,GO:0072066,"The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.",prebend segment development,biological_process
83680,GO:0072067,"The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.",early distal convoluted tubule development,biological_process
83681,GO:0072068,"The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.",late distal convoluted tubule development,biological_process
83682,GO:0072069,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.,DCT cell differentiation,biological_process
83683,GO:0072070,"The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.",loop of Henle development,biological_process
83684,GO:0072071,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.,kidney interstitial fibroblast differentiation,biological_process
83685,GO:0072072,"The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.",kidney stroma development,biological_process
83686,GO:0072073,"The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.",kidney epithelium development,biological_process
83687,GO:0072074,The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.,kidney mesenchyme development,biological_process
83688,GO:0072075,The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.,metanephric mesenchyme development,biological_process
83689,GO:0072076,The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.,nephrogenic mesenchyme development,biological_process
83690,GO:0072077,"The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.",renal vesicle morphogenesis,biological_process
83691,GO:0072078,"The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.",nephron tubule morphogenesis,biological_process
83692,GO:0072079,"The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.",nephron tubule formation,biological_process
83693,GO:0072080,"The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.",nephron tubule development,biological_process
83694,GO:0072081,The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.,specification of nephron tubule identity,biological_process
83695,GO:0072082,The process in which the proximal tubule of the kidney nephron acquires its identity.,specification of proximal tubule identity,biological_process
83696,GO:0072084,The process in which the distal tubule of the kidney nephron acquires its identity.,specification of distal tubule identity,biological_process
83697,GO:0072085,The process in which the connecting tubule of the kidney nephron acquires its identity.,specification of connecting tubule identity,biological_process
83698,GO:0072086,The process in which the loop of Henle of the kidney nephron acquires its identity.,specification of loop of Henle identity,biological_process
83699,GO:0072087,"The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.",renal vesicle development,biological_process
83700,GO:0072088,The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.,nephron epithelium morphogenesis,biological_process
83701,GO:0072089,"The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.",stem cell proliferation,biological_process
83702,GO:0072091,"Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.",regulation of stem cell proliferation,biological_process
83703,GO:0072092,The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.,ureteric bud invasion,biological_process
83704,GO:0072093,The developmental process pertaining to the initial formation of the metanephros.,metanephric renal vesicle formation,biological_process
83705,GO:0072094,Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.,metanephric renal vesicle induction,biological_process
83706,GO:0072095,"Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.",regulation of branch elongation involved in ureteric bud branching,biological_process
83707,GO:0072099,The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.,anterior/posterior pattern specification involved in ureteric bud development,biological_process
83708,GO:0072100,The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.,specification of ureteric bud anterior/posterior symmetry,biological_process
83709,GO:0072102,The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.,glomerulus morphogenesis,biological_process
83710,GO:0072103,The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.,glomerulus vasculature morphogenesis,biological_process
83711,GO:0072104,The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.,glomerular capillary formation,biological_process
83712,GO:0072105,"A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.",ureteric peristalsis,biological_process
83713,GO:0072106,Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.,regulation of ureteric bud formation,biological_process
83714,GO:0072107,Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.,positive regulation of ureteric bud formation,biological_process
83715,GO:0072108,"Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.",positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis,biological_process
83716,GO:0072109,"The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.",glomerular mesangium development,biological_process
83717,GO:0072110,"The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.",glomerular mesangial cell proliferation,biological_process
83718,GO:0072111,"The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.",cell proliferation involved in kidney development,biological_process
83719,GO:0072112,The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.,podocyte differentiation,biological_process
83720,GO:0072113,"The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.",head kidney development,biological_process
83721,GO:0072114,"The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.",pronephros morphogenesis,biological_process
83722,GO:0072115,The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.,head kidney morphogenesis,biological_process
83723,GO:0072116,"The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.",pronephros formation,biological_process
83724,GO:0072117,The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.,head kidney formation,biological_process
83725,GO:0072118,"The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.",pronephros structural organization,biological_process
83726,GO:0072119,The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.,head kidney structural organization,biological_process
83727,GO:0072120,"A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.",pronephros maturation,biological_process
83728,GO:0072121,"A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.",head kidney maturation,biological_process
83729,GO:0072122,"The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.",extraglomerular mesangial cell proliferation,biological_process
83730,GO:0072123,"The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.",intraglomerular mesangial cell proliferation,biological_process
83731,GO:0072124,"Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.",regulation of glomerular mesangial cell proliferation,biological_process
83732,GO:0072125,"Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.",negative regulation of glomerular mesangial cell proliferation,biological_process
83733,GO:0072126,"Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.",positive regulation of glomerular mesangial cell proliferation,biological_process
83734,GO:0072127,"The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the...",renal capsule development,biological_process
83735,GO:0072128,"The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron inductio...",renal capsule morphogenesis,biological_process
83736,GO:0072129,"The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron ...",renal capsule formation,biological_process
83737,GO:0072130,The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,renal capsule specification,biological_process
83738,GO:0072131,The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.,kidney mesenchyme morphogenesis,biological_process
83739,GO:0072132,The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.,mesenchyme morphogenesis,biological_process
83740,GO:0072133,The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.,metanephric mesenchyme morphogenesis,biological_process
83741,GO:0072134,The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.,nephrogenic mesenchyme morphogenesis,biological_process
83742,GO:0072135,"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.",kidney mesenchymal cell proliferation,biological_process
83743,GO:0072136,"The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.",metanephric mesenchymal cell proliferation involved in metanephros development,biological_process
83744,GO:0072137,"The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.",condensed mesenchymal cell proliferation,biological_process
83745,GO:0072138,"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.",mesenchymal cell proliferation involved in ureteric bud development,biological_process
83746,GO:0072139,The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.,glomerular parietal epithelial cell differentiation,biological_process
83747,GO:0072140,"The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.",DCT cell development,biological_process
83748,GO:0072141,"The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.",renal interstitial fibroblast development,biological_process
83749,GO:0072142,"The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.",juxtaglomerulus cell development,biological_process
83750,GO:0072143,"The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.",mesangial cell development,biological_process
83751,GO:0072144,"The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.",glomerular mesangial cell development,biological_process
83752,GO:0072145,"The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.",proximal convoluted tubule segment 1 cell development,biological_process
83753,GO:0072146,The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.,DCT cell fate commitment,biological_process
83754,GO:0072147,The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.,glomerular parietal epithelial cell fate commitment,biological_process
83755,GO:0072148,The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.,epithelial cell fate commitment,biological_process
83756,GO:0072149,The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.,podocyte cell fate commitment,biological_process
83757,GO:0072150,The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.,juxtaglomerulus cell fate commitment,biological_process
83758,GO:0072151,The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.,mesangial cell fate commitment,biological_process
83759,GO:0072152,The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.,glomerular mesangial cell fate commitment,biological_process
83760,GO:0072153,The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.,renal interstitial fibroblast fate commitment,biological_process
83761,GO:0072154,The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.,proximal convoluted tubule segment 1 cell fate commitment,biological_process
83762,GO:0072156,The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.,distal tubule morphogenesis,biological_process
83763,GO:0072158,The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.,proximal tubule morphogenesis,biological_process
83764,GO:0072160,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.,nephron tubule epithelial cell differentiation,biological_process
83765,GO:0072161,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.,mesenchymal cell differentiation involved in kidney development,biological_process
83766,GO:0072162,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.,metanephric mesenchymal cell differentiation,biological_process
83767,GO:0072163,"The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.",mesonephric epithelium development,biological_process
83768,GO:0072164,"The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.",mesonephric tubule development,biological_process
83769,GO:0072165,"The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.",anterior mesonephric tubule development,biological_process
83770,GO:0072166,"The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.",posterior mesonephric tubule development,biological_process
83771,GO:0072167,The process in which the tubules of the mesonephros acquire their identity.,specification of mesonephric tubule identity,biological_process
83772,GO:0072168,The process in which the tubules of the anterior mesonephros acquire their identity.,specification of anterior mesonephric tubule identity,biological_process
83773,GO:0072169,The process in which the tubules of the posterior mesonephros acquire their identity.,specification of posterior mesonephric tubule identity,biological_process
83774,GO:0072170,"The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.",metanephric tubule development,biological_process
83775,GO:0072171,The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.,mesonephric tubule morphogenesis,biological_process
83776,GO:0072172,The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.,mesonephric tubule formation,biological_process
83777,GO:0072173,The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.,metanephric tubule morphogenesis,biological_process
83778,GO:0072174,The developmental process pertaining to the initial formation of a metanephric tubule.,metanephric tubule formation,biological_process
83779,GO:0072175,The developmental process pertaining to the initial formation of an epithelial tube.,epithelial tube formation,biological_process
83780,GO:0072176,"The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.",nephric duct development,biological_process
83781,GO:0072177,"The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.",mesonephric duct development,biological_process
83782,GO:0072178,The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.,nephric duct morphogenesis,biological_process
83783,GO:0072179,The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.,nephric duct formation,biological_process
83784,GO:0072180,The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.,mesonephric duct morphogenesis,biological_process
83785,GO:0072181,The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.,mesonephric duct formation,biological_process
83786,GO:0072182,"Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.",regulation of nephron tubule epithelial cell differentiation,biological_process
83787,GO:0072183,"Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.",negative regulation of nephron tubule epithelial cell differentiation,biological_process
83788,GO:0072184,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.,renal vesicle progenitor cell differentiation,biological_process
83789,GO:0072185,The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.,metanephric cap development,biological_process
83790,GO:0072186,The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.,metanephric cap morphogenesis,biological_process
83791,GO:0072187,The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.,metanephric cap formation,biological_process
83792,GO:0072188,The process in which the metanephric cap acquires its identity.,metanephric cap specification,biological_process
83793,GO:0072189,"The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.",ureter development,biological_process
83794,GO:0072190,"The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.",ureter urothelium development,biological_process
83795,GO:0072191,"The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.",ureter smooth muscle development,biological_process
83796,GO:0072192,The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.,ureter epithelial cell differentiation,biological_process
83797,GO:0072193,The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.,ureter smooth muscle cell differentiation,biological_process
83798,GO:0072194,"The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.",kidney smooth muscle tissue development,biological_process
83799,GO:0072195,The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.,kidney smooth muscle cell differentiation,biological_process
83800,GO:0072196,The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.,proximal/distal pattern formation involved in pronephric nephron development,biological_process
83801,GO:0072197,The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.,ureter morphogenesis,biological_process
83802,GO:0072198,"The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.",mesenchymal cell proliferation involved in ureter development,biological_process
83803,GO:0072200,"Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.",negative regulation of mesenchymal cell proliferation involved in ureter development,biological_process
83804,GO:0072201,"Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.",negative regulation of mesenchymal cell proliferation,biological_process
83805,GO:0072203,"The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.",cell proliferation involved in metanephros development,biological_process
83806,GO:0072205,"The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.",metanephric collecting duct development,biological_process
83807,GO:0072206,"The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.",metanephric juxtaglomerular apparatus development,biological_process
83808,GO:0072207,"The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.",metanephric epithelium development,biological_process
83809,GO:0072208,"The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.",metanephric smooth muscle tissue development,biological_process
83810,GO:0072209,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.,metanephric mesangial cell differentiation,biological_process
83811,GO:0072210,"The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.",metanephric nephron development,biological_process
83812,GO:0072211,"The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.",metanephric pyramids development,biological_process
83813,GO:0072213,"The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.",metanephric capsule development,biological_process
83814,GO:0072214,"The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.",metanephric cortex development,biological_process
83815,GO:0072215,"Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.",regulation of metanephros development,biological_process
83816,GO:0072216,"Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",positive regulation of metanephros development,biological_process
83817,GO:0072217,"Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",negative regulation of metanephros development,biological_process
83818,GO:0072218,"The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.",metanephric ascending thin limb development,biological_process
83819,GO:0072219,"The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.",metanephric cortical collecting duct development,biological_process
83820,GO:0072220,"The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.",metanephric descending thin limb development,biological_process
83821,GO:0072221,"The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.",metanephric distal convoluted tubule development,biological_process
83822,GO:0072222,"The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.",metanephric early distal convoluted tubule development,biological_process
83823,GO:0072223,"The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.",metanephric glomerular mesangium development,biological_process
83824,GO:0072224,"The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.",metanephric glomerulus development,biological_process
83825,GO:0072225,"The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.",metanephric late distal convoluted tubule development,biological_process
83826,GO:0072226,"The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.",metanephric long descending thin limb bend development,biological_process
83827,GO:0072227,"The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.",metanephric macula densa development,biological_process
83828,GO:0072228,"The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.",metanephric prebend segment development,biological_process
83829,GO:0072229,"The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.",metanephric proximal convoluted tubule development,biological_process
83830,GO:0072230,"The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.",metanephric proximal straight tubule development,biological_process
83831,GO:0072231,"The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.",metanephric proximal convoluted tubule segment 1 development,biological_process
83832,GO:0072232,"The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.",metanephric proximal convoluted tubule segment 2 development,biological_process
83833,GO:0072233,"The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.",metanephric thick ascending limb development,biological_process
83834,GO:0072234,"The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.",metanephric nephron tubule development,biological_process
83835,GO:0072235,"The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.",metanephric distal tubule development,biological_process
83836,GO:0072236,"The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.",metanephric loop of Henle development,biological_process
83837,GO:0072237,"The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.",metanephric proximal tubule development,biological_process
83838,GO:0072238,"The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.",metanephric long nephron development,biological_process
83839,GO:0072239,The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.,metanephric glomerulus vasculature development,biological_process
83840,GO:0072240,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.,metanephric DCT cell differentiation,biological_process
83841,GO:0072241,"The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.",metanephric DCT cell development,biological_process
83842,GO:0072242,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.,metanephric DCT cell fate commitment,biological_process
83843,GO:0072243,"The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.",metanephric nephron epithelium development,biological_process
83844,GO:0072244,"The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to pro...",metanephric glomerular epithelium development,biological_process
83845,GO:0072245,The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.,metanephric glomerular parietal epithelial cell differentiation,biological_process
83846,GO:0072246,"The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.",metanephric glomerular parietal epithelial cell development,biological_process
83847,GO:0072247,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.,metanephric glomerular parietal epithelial cell fate commitment,biological_process
83848,GO:0072248,The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.,metanephric podocyte differentiation,biological_process
83849,GO:0072249,"The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.",metanephric podocyte development,biological_process
83850,GO:0072250,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.,metanephric podocyte cell fate commitment,biological_process
83851,GO:0072251,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.,metanephric juxtaglomerulus cell differentiation,biological_process
83852,GO:0072252,"The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.",metanephric juxtaglomerulus cell development,biological_process
83853,GO:0072253,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.,metanephric juxtaglomerulus cell fate commitment,biological_process
83854,GO:0072254,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.,metanephric glomerular mesangial cell differentiation,biological_process
83855,GO:0072255,"The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.",metanephric glomerular mesangial cell development,biological_process
83856,GO:0072256,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.,metanephric glomerular mesangial cell fate commitment,biological_process
83857,GO:0072257,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.,metanephric nephron tubule epithelial cell differentiation,biological_process
83858,GO:0072258,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.,metanephric interstitial fibroblast differentiation,biological_process
83859,GO:0072259,"The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.",metanephric interstitial fibroblast development,biological_process
83860,GO:0072260,The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.,metanephric interstitial fibroblast fate commitment,biological_process
83861,GO:0072262,"The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.",metanephric glomerular mesangial cell proliferation involved in metanephros development,biological_process
83862,GO:0072263,"The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.",metanephric intraglomerular mesangial cell proliferation,biological_process
83863,GO:0072264,"The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.",metanephric glomerular endothelium development,biological_process
83864,GO:0072265,"The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.",metanephric capsule morphogenesis,biological_process
83865,GO:0072266,"The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.",metanephric capsule formation,biological_process
83866,GO:0072267,The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,metanephric capsule specification,biological_process
83867,GO:0072268,Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.,pattern specification involved in metanephros development,biological_process
83868,GO:0072269,"The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.",metanephric long descending thin limb development,biological_process
83869,GO:0072270,"The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.",metanephric short nephron development,biological_process
83870,GO:0072271,"The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.",metanephric short descending thin limb development,biological_process
83871,GO:0072272,The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).,proximal/distal pattern formation involved in metanephric nephron development,biological_process
83872,GO:0072273,The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.,metanephric nephron morphogenesis,biological_process
83873,GO:0072274,"The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.",metanephric glomerular basement membrane development,biological_process
83874,GO:0072275,"The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.",metanephric glomerulus morphogenesis,biological_process
83875,GO:0072276,The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.,metanephric glomerulus vasculature morphogenesis,biological_process
83876,GO:0072277,The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.,metanephric glomerular capillary formation,biological_process
83877,GO:0072278,The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.,metanephric comma-shaped body morphogenesis,biological_process
83878,GO:0072282,"The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.",metanephric nephron tubule morphogenesis,biological_process
83879,GO:0072283,"The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.",metanephric renal vesicle morphogenesis,biological_process
83880,GO:0072284,The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.,metanephric S-shaped body morphogenesis,biological_process
83881,GO:0072285,"A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.",mesenchymal to epithelial transition involved in metanephric renal vesicle formation,biological_process
83882,GO:0072286,"The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.",metanephric connecting tubule development,biological_process
83883,GO:0072287,The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.,metanephric distal tubule morphogenesis,biological_process
83884,GO:0072288,The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.,metanephric proximal tubule morphogenesis,biological_process
83885,GO:0072289,The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.,metanephric nephron tubule formation,biological_process
83886,GO:0072293,The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.,specification of metanephric nephron tubule identity,biological_process
83887,GO:0072294,The process in which the connecting tubule of the metanephric nephron acquires its identity.,specification of metanephric connecting tubule identity,biological_process
83888,GO:0072295,The process in which the distal tubule of the metanephric nephron acquires its identity.,specification of metanephric distal tubule identity,biological_process
83889,GO:0072296,The process in which the loop of Henle of the metanephric nephron acquires its identity.,specification of metanephric loop of Henle identity,biological_process
83890,GO:0072297,The process in which the proximal tubule of the metanephric nephron acquires its identity.,specification of metanephric proximal tubule identity,biological_process
83891,GO:0072298,"Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.",regulation of metanephric glomerulus development,biological_process
83892,GO:0072299,"Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.",negative regulation of metanephric glomerulus development,biological_process
83893,GO:0072300,"Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.",positive regulation of metanephric glomerulus development,biological_process
83894,GO:0072301,"Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.",regulation of metanephric glomerular mesangial cell proliferation,biological_process
83895,GO:0072302,"Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.",negative regulation of metanephric glomerular mesangial cell proliferation,biological_process
83896,GO:0072303,"Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.",positive regulation of glomerular metanephric mesangial cell proliferation,biological_process
83897,GO:0072307,"Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.",regulation of metanephric nephron tubule epithelial cell differentiation,biological_process
83898,GO:0072308,"Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.",negative regulation of metanephric nephron tubule epithelial cell differentiation,biological_process
83899,GO:0072309,The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.,mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis,biological_process
83900,GO:0072310,"The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.",glomerular epithelial cell development,biological_process
83901,GO:0072311,"The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.",glomerular epithelial cell differentiation,biological_process
83902,GO:0072312,"The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.",metanephric glomerular epithelial cell differentiation,biological_process
83903,GO:0072313,"The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.",metanephric glomerular epithelial cell development,biological_process
83904,GO:0072314,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.",glomerular epithelial cell fate commitment,biological_process
83905,GO:0072315,"The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.",metanephric glomerular epithelial cell fate commitment,biological_process
83906,GO:0072318,The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.,clathrin coat disassembly,biological_process
83907,GO:0072319,"The disaggregation of a vesicle coat into its constituent components, resulting in removal of the protein coat from a transport vesicle. Uncoating occurs after vesicle budding and can be coupled to vesicle docking and fusion with the target membrane.",vesicle uncoating,biological_process
83908,GO:0072320,Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.,volume-sensitive chloride channel activity,molecular_function
83909,GO:0072322,The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.,protein transport across periplasmic space,biological_process
83910,GO:0072324,Ascus cytoplasm that is not packaged into ascospores.,ascus epiplasm,cellular_component
83911,GO:0072325,"The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.",vulval cell fate commitment,biological_process
83912,GO:0072326,"The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.",vulval cell fate determination,biological_process
83913,GO:0072327,"The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.",vulval cell fate specification,biological_process
83914,GO:0072328,"Binding to an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.",alkene binding,molecular_function
83915,GO:0072329,"The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.",monocarboxylic acid catabolic process,biological_process
83916,GO:0072330,"The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.",monocarboxylic acid biosynthetic process,biological_process
83917,GO:0072331,An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.,signal transduction by p53 class mediator,biological_process
83918,GO:0072332,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway by p53 class mediator,biological_process
83919,GO:0072334,The process in which UDP-galactose is transported across a membrane.,UDP-galactose transmembrane transport,biological_process
83920,GO:0072337,"The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",modified amino acid transport,biological_process
83921,GO:0072338,"The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.",lactam metabolic process,biological_process
83922,GO:0072339,"The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.",lactam biosynthetic process,biological_process
83923,GO:0072340,"The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.",lactam catabolic process,biological_process
83924,GO:0072341,Binding to a modified amino acid.,modified amino acid binding,molecular_function
83925,GO:0072342,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.",response to anion stress,biological_process
83926,GO:0072343,"The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.",pancreatic stellate cell proliferation,biological_process
83927,GO:0072344,"A process of cytosolic translational elongation that takes place when a cytosolic ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.",rescue of stalled cytosolic ribosome,biological_process
83928,GO:0072345,Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.,NAADP-sensitive calcium-release channel activity,molecular_function
83929,GO:0072346,Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.,cADPR-sensitive calcium-release channel activity,molecular_function
83930,GO:0072347,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.",response to anesthetic,biological_process
83931,GO:0072348,"The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sulfur compound transport,biological_process
83932,GO:0072349,Enables the transfer of modified amino acids from one side of a membrane to the other.,modified amino acid transmembrane transporter activity,molecular_function
83933,GO:0072350,"The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).",tricarboxylic acid metabolic process,biological_process
83934,GO:0072351,"The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.",tricarboxylic acid biosynthetic process,biological_process
83935,GO:0072352,"The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.",tricarboxylic acid catabolic process,biological_process
83936,GO:0072354,Catalysis of the reaction: histone H3-threonine (position 3) + ATP = histone H3-phosphothreonine (position 3) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 3 of histone H3.,histone H3T3 kinase activity,molecular_function
83937,GO:0072356,"A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.",chromosome passenger complex localization to kinetochore,biological_process
83938,GO:0072357,"A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.",PTW/PP1 phosphatase complex,cellular_component
83939,GO:0072359,"The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.",circulatory system development,biological_process
83940,GO:0072360,The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.,vascular cord development,biological_process
83941,GO:0072371,Catalysis of the reaction: histone H2A-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A. This serine residue is present inthe histone H2A of fungi and Tetrahymena. This position corresponds to T120 in metazoa.,histone H2AS121 kinase activity,molecular_function
83942,GO:0072374,"Catalysis of the reaction: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. Zeinoxanthin may also be used as the substrate, in which case lutein is produced.",carotene epsilon hydroxylase activity,molecular_function
83943,GO:0072375,"The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).",medium-term memory,biological_process
83944,GO:0072376,"A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.",protein activation cascade,biological_process
83945,GO:0072377,"A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated Factor Xa by either the intrinsic or extrinsic pathway, to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.","blood coagulation, common pathway",biological_process
83946,GO:0072378,"A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.","blood coagulation, fibrin clot formation",biological_process
83947,GO:0072379,"A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.",ER membrane insertion complex,cellular_component
83948,GO:0072380,"A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.",TRC complex,cellular_component
83949,GO:0072382,"The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.",minus-end-directed vesicle transport along microtubule,biological_process
83950,GO:0072383,"The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.",plus-end-directed vesicle transport along microtubule,biological_process
83951,GO:0072384,"The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.",organelle transport along microtubule,biological_process
83952,GO:0072385,"The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.",minus-end-directed organelle transport along microtubule,biological_process
83953,GO:0072386,"The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.",plus-end-directed organelle transport along microtubule,biological_process
83954,GO:0072387,"The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.",flavin adenine dinucleotide metabolic process,biological_process
83955,GO:0072388,"The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.",flavin adenine dinucleotide biosynthetic process,biological_process
83956,GO:0072389,"The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.",flavin adenine dinucleotide catabolic process,biological_process
83957,GO:0072393,Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.,microtubule anchoring at microtubule organizing center,biological_process
83958,GO:0072396,A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.,response to cell cycle checkpoint signaling,biological_process
83959,GO:0072399,A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.,response to cytokinesis checkpoint signaling,biological_process
83960,GO:0072402,A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.,response to DNA integrity checkpoint signaling,biological_process
83961,GO:0072410,A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.,response to meiotic cell cycle checkpoint signaling,biological_process
83962,GO:0072414,A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.,response to mitotic cell cycle checkpoint signaling,biological_process
83963,GO:0072417,A process that occurs in response to signals generated as a result of spindle checkpoint signaling.,response to spindle checkpoint signaling,biological_process
83964,GO:0072423,A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.,response to DNA damage checkpoint signaling,biological_process
83965,GO:0072426,A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.,response to G2 DNA damage checkpoint signaling,biological_process
83966,GO:0072429,A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.,response to intra-S DNA damage checkpoint signaling,biological_process
83967,GO:0072432,A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.,response to G1 DNA damage checkpoint signaling,biological_process
83968,GO:0072435,A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.,response to mitotic G2 DNA damage checkpoint signaling,biological_process
83969,GO:0072438,A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.,response to DNA replication checkpoint signaling,biological_process
83970,GO:0072441,A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.,response to meiotic DNA replication checkpoint signaling,biological_process
83971,GO:0072444,A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.,response to mitotic DNA replication checkpoint signaling,biological_process
83972,GO:0072449,A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.,response to G1 cell size control checkpoint signaling,biological_process
83973,GO:0072452,A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.,response to G2 transition size control checkpoint signaling,biological_process
83974,GO:0072461,A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.,response to meiotic recombination checkpoint signaling,biological_process
83975,GO:0072464,A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.,response to meiotic spindle assembly checkpoint signaling,biological_process
83976,GO:0072470,A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.,response to cell size control checkpoint signaling,biological_process
83977,GO:0072476,A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.,response to mitotic spindle checkpoint signaling,biological_process
83978,GO:0072479,A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.,response to mitotic cell cycle spindle assembly checkpoint signaling,biological_process
83979,GO:0072482,A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.,response to mitotic cell cycle spindle orientation checkpoint signaling,biological_process
83980,GO:0072485,A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.,response to spindle assembly checkpoint signaling,biological_process
83981,GO:0072487,"A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3.",MSL complex,cellular_component
83982,GO:0072488,The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.,ammonium transmembrane transport,biological_process
83983,GO:0072489,The process in which methylammonium is transported across a membrane.,methylammonium transmembrane transport,biological_process
83984,GO:0072491,"The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.",toluene-containing compound catabolic process,biological_process
83985,GO:0072492,The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.,host cell mitochondrial intermembrane space,cellular_component
83986,GO:0072493,The volume enclosed by the membranes of the host cell endosome.,host cell endosome lumen,cellular_component
83987,GO:0072494,A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.,host multivesicular body,cellular_component
83988,GO:0072495,"A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of trans...",host cell Cajal body,cellular_component
83989,GO:0072496,"Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.",Pup transferase activity,molecular_function
83990,GO:0072497,The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.,mesenchymal stem cell differentiation,biological_process
83991,GO:0072498,"The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.",embryonic skeletal joint development,biological_process
83992,GO:0072499,The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.,photoreceptor cell axon guidance,biological_process
83993,GO:0072513,"Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow t...",positive regulation of secondary heart field cardioblast proliferation,biological_process
83994,GO:0072514,"The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.",trehalose transport in response to water deprivation,biological_process
83995,GO:0072515,"The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.",trehalose transport in response to desiccation,biological_process
83996,GO:0072517,"A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.",host cell viral assembly compartment,cellular_component
83997,GO:0072518,Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.,Rho-dependent protein serine/threonine kinase activity,molecular_function
83998,GO:0072520,"The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.",seminiferous tubule development,biological_process
83999,GO:0072521,"The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.",purine-containing compound metabolic process,biological_process
84000,GO:0072522,"The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.",purine-containing compound biosynthetic process,biological_process
84001,GO:0072523,"The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.",purine-containing compound catabolic process,biological_process
84002,GO:0072524,"The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.",pyridine-containing compound metabolic process,biological_process
84003,GO:0072525,"The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.",pyridine-containing compound biosynthetic process,biological_process
84004,GO:0072526,"The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.",pyridine-containing compound catabolic process,biological_process
84005,GO:0072527,"The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.",pyrimidine-containing compound metabolic process,biological_process
84006,GO:0072528,"The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.",pyrimidine-containing compound biosynthetic process,biological_process
84007,GO:0072529,"The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.",pyrimidine-containing compound catabolic process,biological_process
84008,GO:0072530,The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.,purine-containing compound transmembrane transport,biological_process
84009,GO:0072531,The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.,pyrimidine-containing compound transmembrane transport,biological_process
84010,GO:0072532,Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.,tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity,molecular_function
84011,GO:0072533,Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.,tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity,molecular_function
84012,GO:0072534,A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.,perineuronal net,cellular_component
84013,GO:0072535,"The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",tumor necrosis factor (ligand) superfamily member 11 production,biological_process
84014,GO:0072536,"A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.",interleukin-23 receptor complex,cellular_component
84015,GO:0072537,A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.,fibroblast activation,biological_process
84016,GO:0072538,"An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.",T-helper 17 type immune response,biological_process
84017,GO:0072539,"The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.",T-helper 17 cell differentiation,biological_process
84018,GO:0072540,"The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.",T-helper 17 cell lineage commitment,biological_process
84019,GO:0072541,Catalysis of the reaction: [protein]-dithiol + ONOO- = [protein]-disulfide + NO2- + H2O.,peroxynitrite reductase activity,molecular_function
84020,GO:0072542,Binds to and increases the activity of a protein phosphatase.,protein phosphatase activator activity,molecular_function
84021,GO:0072544,"Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.",L-DOPA binding,molecular_function
84022,GO:0072545,"Binding to L-tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid.",L-tyrosine binding,molecular_function
84023,GO:0072546,"A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.",EMC complex,cellular_component
84024,GO:0072547,Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.,tricoumaroylspermidine meta-hydroxylase activity,molecular_function
84025,GO:0072548,Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.,dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity,molecular_function
84026,GO:0072549,Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.,monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity,molecular_function
84027,GO:0072550,Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.,triferuloylspermidine meta-hydroxylase activity,molecular_function
84028,GO:0072551,Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.,diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity,molecular_function
84029,GO:0072552,Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.,monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity,molecular_function
84030,GO:0072553,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.",terminal button organization,biological_process
84031,GO:0072554,The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.,blood vessel lumenization,biological_process
84032,GO:0072557,"An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.",IPAF inflammasome complex,cellular_component
84033,GO:0072558,"An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.",NLRP1 inflammasome complex,cellular_component
84034,GO:0072559,"An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytoge...",NLRP3 inflammasome complex,cellular_component
84035,GO:0072560,"A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.",type B pancreatic cell maturation,biological_process
84036,GO:0072562,"A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.",blood microparticle,cellular_component
84037,GO:0072563,"A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.",endothelial microparticle,cellular_component
84038,GO:0072564,"The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.",blood microparticle formation,biological_process
84039,GO:0072565,The cellular component organization process in which microparticles bud off from an endothelial cell.,endothelial microparticle formation,biological_process
84040,GO:0072566,"The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 1 production,biological_process
84041,GO:0072567,"The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 2 production,biological_process
84042,GO:0072570,"Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.",ADP-D-ribose binding,molecular_function
84043,GO:0072571,"Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.",mono-ADP-D-ribose binding,molecular_function
84044,GO:0072572,"Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.",poly-ADP-D-ribose binding,molecular_function
84045,GO:0072573,Tolerance induction directed at lipopolysaccharide antigens.,tolerance induction to lipopolysaccharide,biological_process
84046,GO:0072574,"The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.",hepatocyte proliferation,biological_process
84047,GO:0072576,The process in which the anatomical structures of the liver are generated and organized.,liver morphogenesis,biological_process
84048,GO:0072577,Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.,endothelial cell apoptotic process,biological_process
84049,GO:0072578,The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.,neurotransmitter-gated ion channel clustering,biological_process
84050,GO:0072579,The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.,glycine receptor clustering,biological_process
84051,GO:0072582,Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.,17-beta-hydroxysteroid dehydrogenase (NADP+) activity,molecular_function
84052,GO:0072583,"An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.",clathrin-dependent endocytosis,biological_process
84053,GO:0072584,"An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.",caveolin-mediated endocytosis,biological_process
84054,GO:0072585,Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.,xanthosine nucleotidase activity,molecular_function
84055,GO:0072586,"Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.","DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity",molecular_function
84056,GO:0072587,"Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.","DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity",molecular_function
84057,GO:0072588,"A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of stru...",box H/ACA RNP complex,cellular_component
84058,GO:0072589,"A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.",box H/ACA scaRNP complex,cellular_component
84059,GO:0072590,Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.,N-acetyl-L-aspartate-L-glutamate ligase activity,molecular_function
84060,GO:0072591,Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.,citrate-L-glutamate ligase activity,molecular_function
84061,GO:0072592,The chemical reactions and pathways involving diatomic oxygen (O2).,oxygen metabolic process,biological_process
84062,GO:0072593,"The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.",reactive oxygen species metabolic process,biological_process
84063,GO:0072594,The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.,establishment of protein localization to organelle,biological_process
84064,GO:0072595,"Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.",maintenance of protein localization in organelle,biological_process
84065,GO:0072596,The directed movement of a protein to a specific location in a chloroplast.,establishment of protein localization to chloroplast,biological_process
84066,GO:0072597,"Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.",maintenance of protein location in chloroplast,biological_process
84067,GO:0072598,"A process in which a protein is transported to, or maintained at, a location in a chloroplast.",protein localization to chloroplast,biological_process
84068,GO:0072599,The directed movement of a protein to a specific location in the endoplasmic reticulum.,establishment of protein localization to endoplasmic reticulum,biological_process
84069,GO:0072627,"The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-28A production,biological_process
84070,GO:0072629,"The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-28B production,biological_process
84071,GO:0072631,"The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-29 production,biological_process
84072,GO:0072633,"The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-30 production,biological_process
84073,GO:0072635,"The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-31 production,biological_process
84074,GO:0072637,"The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-32 production,biological_process
84075,GO:0072639,"The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-33 production,biological_process
84076,GO:0072645,"The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-delta production,biological_process
84077,GO:0072647,"The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-epsilon production,biological_process
84078,GO:0072649,"The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-kappa production,biological_process
84079,GO:0072651,"The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-tau production,biological_process
84080,GO:0072653,"The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interferon-omega production,biological_process
84081,GO:0072656,"Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.",maintenance of protein location in mitochondrion,biological_process
84082,GO:0072657,"A process in which a protein is transported to, or maintained in, a specific location in a membrane.",protein localization to membrane,biological_process
84083,GO:0072658,"Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.",maintenance of protein location in membrane,biological_process
84084,GO:0072659,"A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.",protein localization to plasma membrane,biological_process
84085,GO:0072660,"Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.",maintenance of protein location in plasma membrane,biological_process
84086,GO:0072662,"A process in which a protein is transported to, or maintained at, a location in a peroxisome.",protein localization to peroxisome,biological_process
84087,GO:0072663,The directed movement of a protein to a specific location in a peroxisome.,establishment of protein localization to peroxisome,biological_process
84088,GO:0072664,"Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.",maintenance of protein location in peroxisome,biological_process
84089,GO:0072665,"A process in which a protein is transported to, or maintained at, a location in a vacuole.",protein localization to vacuole,biological_process
84090,GO:0072666,The directed movement of a protein to a specific location in a vacuole.,establishment of protein localization to vacuole,biological_process
84091,GO:0072667,"Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.",maintenance of protein location in vacuole,biological_process
84092,GO:0072669,"A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.",tRNA-splicing ligase complex,cellular_component
84093,GO:0072670,"The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).",mitochondrial tRNA threonylcarbamoyladenosine modification,biological_process
84094,GO:0072671,The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.,mitochondria-associated ubiquitin-dependent protein catabolic process,biological_process
84095,GO:0072672,The migration of a neutrophil from the blood vessels into the surrounding tissue.,neutrophil extravasation,biological_process
84096,GO:0072673,A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.,lamellipodium morphogenesis,biological_process
84097,GO:0072674,The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.,multinuclear osteoclast differentiation,biological_process
84098,GO:0072675,The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.,osteoclast fusion,biological_process
84099,GO:0072676,The movement of a lymphocyte within or between different tissues and organs of the body.,lymphocyte migration,biological_process
84100,GO:0072677,The movement of an eosinophil within or between different tissues and organs of the body.,eosinophil migration,biological_process
84101,GO:0072678,The movement of a T cell within or between different tissues and organs of the body.,T cell migration,biological_process
84102,GO:0072679,"The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.",thymocyte migration,biological_process
84103,GO:0072680,"The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.",extracellular matrix-dependent thymocyte migration,biological_process
84104,GO:0072681,"The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.",fibronectin-dependent thymocyte migration,biological_process
84105,GO:0072682,The migration of an eosinophil from the blood vessels into the surrounding tissue.,eosinophil extravasation,biological_process
84106,GO:0072683,The migration of a T cell from the blood vessels into the surrounding tissue.,T cell extravasation,biological_process
84107,GO:0072685,"The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.",Mre11 complex assembly,biological_process
84108,GO:0072686,A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.,mitotic spindle,cellular_component
84109,GO:0072687,"A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.",meiotic spindle,cellular_component
84110,GO:0072688,"Any process in which a SHREC complex is transported to, or maintained in, a specific location.",SHREC complex localization,biological_process
84111,GO:0072689,"The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.",MCM complex assembly,biological_process
84112,GO:0072690,"A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.",single-celled organism vegetative growth phase,biological_process
84113,GO:0072695,"Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.",regulation of DNA recombination at telomere,biological_process
84114,GO:0072696,"Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.",positive regulation of DNA recombination at telomere,biological_process
84115,GO:0072697,"A process in which a protein is transported to, or maintained in, the cell cortex.",protein localization to cell cortex,biological_process
84116,GO:0072698,"A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.",protein localization to microtubule cytoskeleton,biological_process
84117,GO:0072699,"A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton.",protein localization to cortical microtubule cytoskeleton,biological_process
84118,GO:0072700,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.",response to bismuth,biological_process
84119,GO:0072701,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.",cellular response to bismuth,biological_process
84120,GO:0072702,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.",response to methyl methanesulfonate,biological_process
84121,GO:0072703,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.",cellular response to methyl methanesulfonate,biological_process
84122,GO:0072704,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.",response to mercaptoethanol,biological_process
84123,GO:0072705,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.",cellular response to mercaptoethanol,biological_process
84124,GO:0072706,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.",response to sodium dodecyl sulfate,biological_process
84125,GO:0072707,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.",cellular response to sodium dodecyl sulfate,biological_process
84126,GO:0072708,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.",response to sorbitol,biological_process
84127,GO:0072709,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.",cellular response to sorbitol,biological_process
84128,GO:0072710,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.",response to hydroxyurea,biological_process
84129,GO:0072711,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.",cellular response to hydroxyurea,biological_process
84130,GO:0072712,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.",response to thiabendazole,biological_process
84131,GO:0072713,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.",cellular response to thiabendazole,biological_process
84132,GO:0072714,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.",response to selenite ion,biological_process
84133,GO:0072715,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.",cellular response to selenite ion,biological_process
84134,GO:0072716,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.",response to actinomycin D,biological_process
84135,GO:0072717,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.",cellular response to actinomycin D,biological_process
84136,GO:0072718,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.",response to cisplatin,biological_process
84137,GO:0072719,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.",cellular response to cisplatin,biological_process
84138,GO:0072720,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.",response to dithiothreitol,biological_process
84139,GO:0072721,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.",cellular response to dithiothreitol,biological_process
84140,GO:0072722,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.",response to amitrole,biological_process
84141,GO:0072723,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.",cellular response to amitrole,biological_process
84142,GO:0072724,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.",response to 4-nitroquinoline N-oxide,biological_process
84143,GO:0072725,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.",cellular response to 4-nitroquinoline N-oxide,biological_process
84144,GO:0072728,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.",response to Gentian violet,biological_process
84145,GO:0072729,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.",cellular response to Gentian violet,biological_process
84146,GO:0072730,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.",response to papulacandin B,biological_process
84147,GO:0072731,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.",cellular response to papulacandin B,biological_process
84148,GO:0072732,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.",cellular response to calcium ion starvation,biological_process
84149,GO:0072733,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.",response to staurosporine,biological_process
84150,GO:0072734,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.",cellular response to staurosporine,biological_process
84151,GO:0072735,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.",response to tert-butyl hydroperoxide,biological_process
84152,GO:0072736,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.",cellular response to tert-butyl hydroperoxide,biological_process
84153,GO:0072737,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.",response to diamide,biological_process
84154,GO:0072738,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.",cellular response to diamide,biological_process
84155,GO:0072739,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.",response to anisomycin,biological_process
84156,GO:0072740,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.",cellular response to anisomycin,biological_process
84157,GO:0072741,"A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division.",protein localization to cell division site,biological_process
84158,GO:0072742,"Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.",SAGA complex localization to transcription regulatory region,biological_process
84159,GO:0072743,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.",cellular response to erythromycin,biological_process
84160,GO:0072744,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.",cellular response to trichodermin,biological_process
84161,GO:0072745,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.",cellular response to antimycin A,biological_process
84162,GO:0072746,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.",cellular response to tetracycline,biological_process
84163,GO:0072747,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.",cellular response to chloramphenicol,biological_process
84164,GO:0072748,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus.",cellular response to tacrolimus,biological_process
84165,GO:0072749,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.",cellular response to cytochalasin B,biological_process
84166,GO:0072750,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.",cellular response to leptomycin B,biological_process
84167,GO:0072751,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.",cellular response to L-thialysine,biological_process
84168,GO:0072752,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.",cellular response to rapamycin,biological_process
84169,GO:0072753,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.",cellular response to glutathione,biological_process
84170,GO:0072754,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.",cellular response to purvalanol A,biological_process
84171,GO:0072756,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.",cellular response to paraquat,biological_process
84172,GO:0072757,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.",cellular response to camptothecin,biological_process
84173,GO:0072758,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.",response to topoisomerase inhibitor,biological_process
84174,GO:0072759,"Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.",cellular response to topoisomerase inhibitor,biological_process
84175,GO:0072760,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.",cellular response to GW 7647,biological_process
84176,GO:0072761,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.",cellular response to capsazepine,biological_process
84177,GO:0072762,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.",cellular response to carbendazim,biological_process
84178,GO:0072763,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.",cellular response to hesperadin,biological_process
84179,GO:0072764,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.",cellular response to reversine,biological_process
84180,GO:0072765,"A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.",centromere localization,biological_process
84181,GO:0072766,"The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei.",centromere clustering at the mitotic interphase nuclear envelope,biological_process
84182,GO:0075000,"Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host osmotic environment,biological_process
84183,GO:0075001,"The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.",adhesion of symbiont infection structure to host,biological_process
84184,GO:0075002,The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont germination tube to host,biological_process
84185,GO:0075003,The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont appressorium to host,biological_process
84186,GO:0075004,"The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.",adhesion of symbiont spore to host,biological_process
84187,GO:0075009,Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,germ tube formation,biological_process
84188,GO:0075010,"Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of germ tube formation,biological_process
84189,GO:0075011,"Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of germ tube formation,biological_process
84190,GO:0075012,"Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of germ tube formation,biological_process
84191,GO:0075015,"The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.",formation of infection structure,biological_process
84192,GO:0075016,"The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.",appressorium formation,biological_process
84193,GO:0075017,"Any process that modulates the frequency, rate or extent of symbiont appressorium formation.",regulation of appressorium formation,biological_process
84194,GO:0075018,"Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation.",positive regulation of appressorium formation,biological_process
84195,GO:0075019,"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.",negative regulation of appressorium formation,biological_process
84196,GO:0075025,The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,initiation of appressorium formation,biological_process
84197,GO:0075029,The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation.,formation of appressorium germ tube hook structure,biological_process
84198,GO:0075030,"Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation.",modulation of formation of symbiont germ tube hook structure for appressorium development,biological_process
84199,GO:0075031,"Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation.",positive regulation of formation of symbiont germ tube hook structure for appressorium development,biological_process
84200,GO:0075032,"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation.",negative regulation of formation of symbiont germ tube hook structure for appressorium development,biological_process
84201,GO:0075035,"The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",appressorium maturation,biological_process
84202,GO:0075039,The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,establishment of turgor in appressorium,biological_process
84203,GO:0075043,The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium.,melanization of appressorium wall,biological_process
84204,GO:0075045,"Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of formation by symbiont of haustorium for nutrient acquisition from host,biological_process
84205,GO:0075046,"Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of formation by symbiont of haustorium for nutrient acquisition from host,biological_process
84206,GO:0075053,"The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.",penetration peg formation,biological_process
84207,GO:0075054,"Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",modulation of penetration peg formation,biological_process
84208,GO:0075055,"Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of penetration peg formation,biological_process
84209,GO:0075069,The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont infection cushion to host,biological_process
84210,GO:0075070,The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont hyphopodium to host,biological_process
84211,GO:0075071,A process in which a symbiont alters or subverts autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host autophagy,biological_process
84212,GO:0075109,A process by which a symbiont alters or subverts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host receptor-mediated signal transduction,biological_process
84213,GO:0075111,"A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host receptor-mediated signal transduction,biological_process
84214,GO:0075118,A process by which a symbiont alters or subverts the normal execution of a host G protein-coupled receptor signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host G protein-coupled receptor signal transduction pathway,biological_process
84215,GO:0075120,"A process in which a symbiont interferes with, inhibits or disrupts a G protein-coupled receptor signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host G protein-coupled receptor signal transduction,biological_process
84216,GO:0075135,"A process in which a symbiont interferes with, inhibits or disrupts a calcium signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host calcium-mediated signal transduction,biological_process
84217,GO:0075136,"Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host,biological_process
84218,GO:0075137,"Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host redox environment,biological_process
84219,GO:0075138,"Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host oxygen tension environment,biological_process
84220,GO:0075139,"Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host iron concentration,biological_process
84221,GO:0075183,The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.,infection cushion formation,biological_process
84222,GO:0075184,"Any process that modulates the frequency, rate or extent of symbiont infection cushion formation.",regulation of infection cushion formation,biological_process
84223,GO:0075185,"Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of infection cushion formation,biological_process
84224,GO:0075186,"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of infection cushion formation,biological_process
84225,GO:0075187,"The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.",hyphopodium formation,biological_process
84226,GO:0075188,"Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of hyphopodium formation,biological_process
84227,GO:0075189,"Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of hyphopodium formation,biological_process
84228,GO:0075190,"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of hyphopodium formation,biological_process
84229,GO:0075192,"The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",haustorium mother cell formation,biological_process
84230,GO:0075193,"Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of haustorium mother cell formation,biological_process
84231,GO:0075194,"Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of haustorium mother cell formation,biological_process
84232,GO:0075195,"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of haustorium mother cell formation,biological_process
84233,GO:0075196,The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont haustorium mother cell to host,biological_process
84234,GO:0075197,The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.,haustorium neck formation,biological_process
84235,GO:0075198,"Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",modulation of symbiont haustorium neck formation for entry into host,biological_process
84236,GO:0075199,"Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of symbiont haustorium neck formation for entry into host,biological_process
84237,GO:0075201,"The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is define...",penetration hypha formation,biological_process
84238,GO:0075202,"Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of penetration hypha formation,biological_process
84239,GO:0075203,"Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of penetration hypha formation,biological_process
84240,GO:0075210,"A process in which a symbiont interferes with, inhibits or disrupts a cAMP/PKA signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host cAMP/PKA signal transduction,biological_process
84241,GO:0075214,"The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.",spore encystment,biological_process
84242,GO:0075215,"Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",modulation of spore encystment on host,biological_process
84243,GO:0075216,"Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of spore encystment on host,biological_process
84244,GO:0075217,"Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of spore encystment on host,biological_process
84245,GO:0075218,"The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.",zoospore encystment on host,biological_process
84246,GO:0075219,"Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",modulation of zoospore encystment on host,biological_process
84247,GO:0075220,"Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of zoospore encystment on host,biological_process
84248,GO:0075221,"Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",negative regulation of zoospore encystment on host,biological_process
84249,GO:0075222,"The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores.",sporangium germination,biological_process
84250,GO:0075223,"Any process that modulates the frequency, rate or extent of sporangium germination.",regulation of sporangium germination,biological_process
84251,GO:0075224,"Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination.",positive regulation of sporangium germination,biological_process
84252,GO:0075225,"Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination.",negative regulation of sporangium germination,biological_process
84253,GO:0075226,"The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction.",encysted zoospore germination,biological_process
84254,GO:0075227,"Any process that modulates the frequency, rate or extent of an encysted zoospore germination.",regulation of encysted zoospore germination,biological_process
84255,GO:0075228,"Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination.",positive regulation of encysted zoospore germination,biological_process
84256,GO:0075229,"Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination.",negative regulation of encysted zoospore germination,biological_process
84257,GO:0075239,"The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.",zoospore formation,biological_process
84258,GO:0075240,"Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.",regulation of zoospore formation,biological_process
84259,GO:0075241,"Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.",positive regulation of zoospore formation,biological_process
84260,GO:0075242,"Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.",negative regulation of zoospore formation,biological_process
84261,GO:0075243,"The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.",oospore formation,biological_process
84262,GO:0075244,"Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.",regulation of oospore formation,biological_process
84263,GO:0075245,"Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.",positive regulation of oospore formation,biological_process
84264,GO:0075246,"Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.",negative regulation of oospore formation,biological_process
84265,GO:0075247,"The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host.",aeciospore formation,biological_process
84266,GO:0075248,"Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.",regulation of aeciospore formation,biological_process
84267,GO:0075249,"Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.",positive regulation of aeciospore formation,biological_process
84268,GO:0075250,"Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.",negative regulation of aeciospore formation,biological_process
84269,GO:0075251,"The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus.",uredospore formation,biological_process
84270,GO:0075252,"Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.",regulation of uredospore formation,biological_process
84271,GO:0075253,"Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.",positive regulation of uredospore formation,biological_process
84272,GO:0075254,"Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.",negative regulation of uredospore formation,biological_process
84273,GO:0075255,The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.,teliospore formation,biological_process
84274,GO:0075256,"Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.",regulation of teliospore formation,biological_process
84275,GO:0075257,"Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.",positive regulation of teliospore formation,biological_process
84276,GO:0075258,"Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.",negative regulation of teliospore formation,biological_process
84277,GO:0075259,"The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.",spore-bearing structure development,biological_process
84278,GO:0075260,"Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.",regulation of spore-bearing organ development,biological_process
84279,GO:0075261,"Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.",positive regulation of spore-bearing organ development,biological_process
84280,GO:0075262,"Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.",negative regulation of spore-bearing organ development,biological_process
84281,GO:0075263,"The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.",oogonium development,biological_process
84282,GO:0075264,"Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.",regulation of oogonium development,biological_process
84283,GO:0075265,"Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.",positive regulation of oogonium development,biological_process
84284,GO:0075266,"Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.",negative regulation of oogonium development,biological_process
84285,GO:0075267,"The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium.",aecium development,biological_process
84286,GO:0075268,"Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.",regulation of aecium development,biological_process
84287,GO:0075269,"Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.",positive regulation of aecium development,biological_process
84288,GO:0075270,"Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.",negative regulation of aecium development,biological_process
84289,GO:0075271,"The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.",zygosporangium development,biological_process
84290,GO:0075272,"Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.",regulation of zygosporangium development,biological_process
84291,GO:0075273,"Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.",positive regulation of zygosporangium development,biological_process
84292,GO:0075274,"Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.",negative regulation of zygosporangium development,biological_process
84293,GO:0075275,"The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.",telium development,biological_process
84294,GO:0075276,"Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.",regulation of telium development,biological_process
84295,GO:0075277,"Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.",positive regulation of telium development,biological_process
84296,GO:0075278,"Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.",negative regulation of telium development,biological_process
84297,GO:0075279,"The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.",uredinium development,biological_process
84298,GO:0075280,"Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.",regulation of uredinium development,biological_process
84299,GO:0075281,"Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.",positive regulation of uredinium development,biological_process
84300,GO:0075282,"Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.",negative regulation of uredinium development,biological_process
84301,GO:0075283,"The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.",sporulation resulting in formation of a multicellular or syncytial spore,biological_process
84302,GO:0075284,The formation of a multicellular or syncytial spore via septations derived from mitosis.,asexual sporulation resulting in formation of a multicellular or syncytial spore,biological_process
84303,GO:0075285,"The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.",sexual sporulation resulting in formation of a multicellular or syncytial spore,biological_process
84304,GO:0075286,"Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.",regulation of sporangiospore formation,biological_process
84305,GO:0075287,"Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.",positive regulation of sporangiospore formation,biological_process
84306,GO:0075288,"Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.",negative regulation of sporangiospore formation,biological_process
84307,GO:0075289,"The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.",aplanospore formation,biological_process
84308,GO:0075290,"Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.",regulation of aplanospore formation,biological_process
84309,GO:0075291,"Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.",positive regulation of aplanospore formation,biological_process
84310,GO:0075292,"Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.",negative regulation of aplanospore formation,biological_process
84311,GO:0075293,"Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",response to host pH environment,biological_process
84312,GO:0075294,"Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.",positive regulation by symbiont of entry into host,biological_process
84313,GO:0075296,"Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.",positive regulation of ascospore formation,biological_process
84314,GO:0075297,"Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.",negative regulation of ascospore formation,biological_process
84315,GO:0075298,"Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.",regulation of zygospore formation,biological_process
84316,GO:0075299,"Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.",positive regulation of zygospore formation,biological_process
84317,GO:0075300,"Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.",negative regulation of zygospore formation,biological_process
84318,GO:0075302,"Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.",regulation of basidiospore formation,biological_process
84319,GO:0075303,"Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.",positive regulation of basidiospore formation,biological_process
84320,GO:0075304,"Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.",negative regulation of basidiospore formation,biological_process
84321,GO:0075306,"Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.",regulation of conidium formation,biological_process
84322,GO:0075307,"Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.",positive regulation of conidium formation,biological_process
84323,GO:0075308,"Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.",negative regulation of conidium formation,biological_process
84324,GO:0075310,"Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.",regulation of sporangium development,biological_process
84325,GO:0075311,"Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.",positive regulation of sporangium development,biological_process
84326,GO:0075312,"Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.",negative regulation of sporangium development,biological_process
84327,GO:0075313,"The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.",basidium development,biological_process
84328,GO:0075314,"Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.",regulation of basidium development,biological_process
84329,GO:0075315,"Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.",positive regulation of basidium development,biological_process
84330,GO:0075316,"Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.",negative regulation of basidium development,biological_process
84331,GO:0075317,"The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.",ascus development,biological_process
84332,GO:0075318,"Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.",regulation of ascus development,biological_process
84333,GO:0075319,"Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.",positive regulation of ascus development,biological_process
84334,GO:0075320,"Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.",negative regulation of ascus development,biological_process
84335,GO:0075321,"The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.",oomycete sporangium development,biological_process
84336,GO:0075322,"Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.",regulation of oomycete sporangium development,biological_process
84337,GO:0075323,"Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.",positive regulation of oomycete sporangium development,biological_process
84338,GO:0075324,"Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.",negative regulation of oomycete sporangium development,biological_process
84339,GO:0075325,Any process in which an organism disseminates its spores.,spore dispersal,biological_process
84340,GO:0075328,"The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.",formation of arbuscule for nutrient acquisition,biological_process
84341,GO:0075329,"Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",regulation of arbuscule formation for nutrient acquisition from host,biological_process
84342,GO:0075330,"Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",positive regulation of arbuscule formation for nutrient acquisition from host,biological_process
84343,GO:0075341,A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism.,host cell PML body,cellular_component
84344,GO:0075342,The process in which an organism effects a change that impairs the structure or function of the host PML body. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cell PML body,biological_process
84345,GO:0075502,"Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.",endosome membrane permeabilization involved in viral entry into host cell,biological_process
84346,GO:0075503,"Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.",fusion of virus membrane with host macropinosome membrane,biological_process
84347,GO:0075504,"Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm.",macropinosomal membrane permeabilization involved in viral entry into host cell,biological_process
84348,GO:0075505,Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC).,entry of intact viral capsid into host nucleus through nuclear pore complex,biological_process
84349,GO:0075506,Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.,entry of viral genome into host nucleus through nuclear pore complex via importin,biological_process
84350,GO:0075507,Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm.,entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome,biological_process
84351,GO:0075508,"Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm.",entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm,biological_process
84352,GO:0075509,Any endocytosis that is involved in the uptake of a virus into a host cell.,endocytosis involved in viral entry into host cell,biological_process
84353,GO:0075510,Any macropinocytosis that is involved in the uptake of a virus into a host cell.,macropinocytosis involved in viral entry into host cell,biological_process
84354,GO:0075511,"Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm.",macropinosome lysis involved in viral entry into host cell,biological_process
84355,GO:0075512,"Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.",clathrin-dependent endocytosis of virus by host cell,biological_process
84356,GO:0075513,Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus.,caveolin-mediated endocytosis of virus by host cell,biological_process
84357,GO:0075514,"Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.",endosome lysis involved in viral entry into host cell,biological_process
84358,GO:0075519,The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus.,microtubule-dependent intracellular transport of viral material,biological_process
84359,GO:0075520,"The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.",actin-dependent intracellular transport of virus,biological_process
84360,GO:0075521,"The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.",microtubule-dependent intracellular transport of viral material towards nucleus,biological_process
84361,GO:0075522,"Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.",IRES-dependent viral translational initiation,biological_process
84362,GO:0075523,"A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.",viral translational frameshifting,biological_process
84363,GO:0075524,"A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.",ribosomal skipping,biological_process
84364,GO:0075525,"A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.",viral translational termination-reinitiation,biological_process
84365,GO:0075526,"A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.",cap snatching,biological_process
84366,GO:0075527,"The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon.",viral RNA editing,biological_process
84367,GO:0075529,"A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.",establishment of latency as a circular episome,biological_process
84368,GO:0075530,"A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.",establishment of latency as a linear episome,biological_process
84369,GO:0075606,"The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.",transport of viral material towards nucleus,biological_process
84370,GO:0075713,A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.,establishment of integrated proviral latency,biological_process
84371,GO:0075720,"A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.",establishment of episomal latency,biological_process
84372,GO:0075732,"The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.",viral penetration into host nucleus,biological_process
84373,GO:0075733,"The directed movement of a virus, or part of a virus, within the host cell.",intracellular transport of virus,biological_process
84374,GO:0080001,"The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.",mucilage extrusion from seed coat,biological_process
84375,GO:0080002,Catalysis of the reaction: 4-aminobenzoate + UDP-alpha-D-glucose = 1-O-(4-aminobenzoyl)-beta-D-glucose + UDP.,UDP-glucose:4-aminobenzoate acylglucosyltransferase activity,molecular_function
84376,GO:0080003,The chemical reactions and pathways involving the triterpene thalianol.,thalianol metabolic process,biological_process
84377,GO:0080004,Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15.,thalian-diol desaturase activity,molecular_function
84378,GO:0080005,Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.,photosystem stoichiometry adjustment,biological_process
84379,GO:0080006,"Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.",internode patterning,biological_process
84380,GO:0080007,Catalysis of the reaction: S-nitrosoglutathione + NADH + H+ = S-(hydroxysulfenamide)glutathione + NAD+.,S-nitrosoglutathione reductase (NADH) activity,molecular_function
84381,GO:0080008,A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.,Cul4-RING E3 ubiquitin ligase complex,cellular_component
84382,GO:0080011,"Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.",baruol synthase activity,molecular_function
84383,GO:0080012,Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.,trihydroxyferuloyl spermidine O-methyltransferase activity,molecular_function
84384,GO:0080013,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate.","(E,E)-geranyllinalool synthase activity",molecular_function
84385,GO:0080014,"Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.",thalianol hydroxylase activity,molecular_function
84386,GO:0080015,Catalysis of the reaction: (2E)-geranyl diphosphate = diphosphate + sabinene.,sabinene synthase activity,molecular_function
84387,GO:0080016,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.",(-)-E-beta-caryophyllene synthase activity,molecular_function
84388,GO:0080017,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate.",alpha-humulene synthase activity,molecular_function
84389,GO:0080018,Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP.,anthocyanin 5-O-glucosyltransferase activity,molecular_function
84390,GO:0080019,Catalysis of the reaction: a very long-chain fatty acyl-CoA + 2 NADPH + 2 H+ = a very long-chain primary fatty alcohol + 2 NADP+ + CoA.,alcohol-forming very long-chain fatty acyl-CoA reductase (NADP+) activity,molecular_function
84391,GO:0080020,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.",regulation of coenzyme A biosynthetic process,biological_process
84392,GO:0080021,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.",response to benzoic acid,biological_process
84393,GO:0080022,"The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.",primary root development,biological_process
84394,GO:0080023,Catalysis of the reaction: a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O.,(2E)-enoyl-CoA hydratase activity,molecular_function
84395,GO:0080024,"The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.",indolebutyric acid metabolic process,biological_process
84396,GO:0080025,"Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.","phosphatidylinositol-3,5-bisphosphate binding",molecular_function
84397,GO:0080026,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.",response to indolebutyric acid,biological_process
84398,GO:0080027,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.",response to herbivore,biological_process
84399,GO:0080028,"The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.",nitrile biosynthetic process,biological_process
84400,GO:0080029,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.",cellular response to boron-containing substance levels,biological_process
84401,GO:0080030,Catalysis of the reaction: H2O + methyl (indol-3-yl)acetate = (indol-3-yl)acetate + H+ + methanol.,methyl indole-3-acetate esterase activity,molecular_function
84402,GO:0080031,Catalysis of the reaction: H2O + methyl salicylate = H+ + methanol + salicylate.,methyl salicylate esterase activity,molecular_function
84403,GO:0080032,Catalysis of the reaction: H2O + methyl (-)-jasmonate = H+ + jasmonate + methanol.,methyl jasmonate esterase activity,molecular_function
84404,GO:0080033,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.",response to nitrite,biological_process
84405,GO:0080034,"Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.","host response to induction by symbiont of tumor, nodule or growth in host",biological_process
84406,GO:0080035,"The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.",2-hydroxy-but-3-enyl glucosinolate biosynthetic process,biological_process
84407,GO:0080036,"Any process that modulates the frequency, rate or extent of cytokinin signaling.",regulation of cytokinin-activated signaling pathway,biological_process
84408,GO:0080037,"Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.",negative regulation of cytokinin-activated signaling pathway,biological_process
84409,GO:0080038,"Any process that activates or increases the frequency, rate or extent of cytokinin signaling.",positive regulation of cytokinin-activated signaling pathway,biological_process
84410,GO:0080040,"Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation.",positive regulation of cellular response to phosphate starvation,biological_process
84411,GO:0080041,Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.,ADP-ribose pyrophosphatase activity,molecular_function
84412,GO:0080042,Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.,ADP-glucose pyrophosphatase activity,molecular_function
84413,GO:0080043,Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.,quercetin 3-O-glucosyltransferase activity,molecular_function
84414,GO:0080044,Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.,quercetin 7-O-glucosyltransferase activity,molecular_function
84415,GO:0080045,Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule.,quercetin 3'-O-glucosyltransferase activity,molecular_function
84416,GO:0080046,Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.,quercetin 4'-O-glucosyltransferase activity,molecular_function
84417,GO:0080047,Catalysis of the reaction: GDP-beta-L-galactose + phosphate = beta-L-galactose-1-phosphate + GDP.,GDP-L-galactose phosphorylase activity,molecular_function
84418,GO:0080048,Catalysis of the reaction: GDP-alpha-D-glucose + phosphate = alpha-D-glucose-1-phosphate + GDP.,GDP-D-glucose phosphorylase activity,molecular_function
84419,GO:0080049,"Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.","L-gulono-1,4-lactone dehydrogenase activity",molecular_function
84420,GO:0080050,"Any process that modulates the frequency, rate or extent of seed development.",regulation of seed development,biological_process
84421,GO:0080051,"The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface.",cutin transport,biological_process
84422,GO:0080052,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.",response to histidine,biological_process
84423,GO:0080053,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.",response to phenylalanine,biological_process
84424,GO:0080054,Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity nitrate transmembrane transporter activity,molecular_function
84425,GO:0080056,Vascular tissue pattern formation as it occurs in the petal of vascular plants.,petal vascular tissue pattern formation,biological_process
84426,GO:0080057,Vascular tissue pattern formation as it occurs in the sepal of vascular plants.,sepal vascular tissue pattern formation,biological_process
84427,GO:0080058,The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.,protein deglutathionylation,biological_process
84428,GO:0080059,Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.,flavonol 3-O-arabinosyltransferase activity,molecular_function
84429,GO:0080060,"The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.",integument development,biological_process
84430,GO:0080061,Catalysis of the reaction: (indol-3-yl)acetonitrile + 2 H2O = (indol-3-yl)acetate + NH4+.,indole-3-acetonitrile nitrilase activity,molecular_function
84431,GO:0080062,Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.,cytokinin 9-beta-glucosyltransferase activity,molecular_function
84432,GO:0080064,"A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.","4,4-dimethyl-9beta,19-cyclopropylsterol oxidation",biological_process
84433,GO:0080065,"A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.",4-alpha-methyl-delta7-sterol oxidation,biological_process
84434,GO:0080072,Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.,spermidine:sinapoyl CoA N-acyltransferase activity,molecular_function
84435,GO:0080073,Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.,spermidine:coumaroyl CoA N-acyltransferase activity,molecular_function
84436,GO:0080074,Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.,spermidine:caffeoyl CoA N-acyltransferase activity,molecular_function
84437,GO:0080075,Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.,spermidine:feruloyl CoA N-acyltransferase activity,molecular_function
84438,GO:0080077,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.,trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity,molecular_function
84439,GO:0080078,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.,tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity,molecular_function
84440,GO:0080079,Catalysis of the reaction: D-cellobiose + H2O = 2 D-glucose.,cellobiose glucosidase activity,molecular_function
84441,GO:0080081,Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.,4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity,molecular_function
84442,GO:0080082,Catalysis of the hydrolysis of glucosidic link in esculin.,esculin beta-glucosidase activity,molecular_function
84443,GO:0080083,Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.,beta-gentiobiose beta-glucosidase activity,molecular_function
84444,GO:0080084,"Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.",5S rDNA binding,molecular_function
84445,GO:0080085,A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast.,"signal recognition particle, chloroplast targeting",cellular_component
84446,GO:0080086,"The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen.",stamen filament development,biological_process
84447,GO:0080088,The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.,spermidine hydroxycinnamate conjugate biosynthetic process,biological_process
84448,GO:0080089,Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.,sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity,molecular_function
84449,GO:0080090,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.",regulation of primary metabolic process,biological_process
84450,GO:0080091,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.",regulation of raffinose metabolic process,biological_process
84451,GO:0080092,"Any process that modulates the frequency, rate or extent of pollen tube growth.",regulation of pollen tube growth,biological_process
84452,GO:0080093,"Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved.",regulation of photorespiration,biological_process
84453,GO:0080094,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.",response to trehalose-6-phosphate,biological_process
84454,GO:0080095,Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.,phosphatidylethanolamine-sterol O-acyltransferase activity,molecular_function
84455,GO:0080096,Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.,phosphatidate-sterol O-acyltransferase activity,molecular_function
84456,GO:0080097,Catalysis of the reaction: L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine.,L-tryptophan:pyruvate transaminase activity,molecular_function
84457,GO:0080098,Catalysis of the reaction: L-tyrosine + pyruvate = 3-(4-hydroxyphenyl)pyruvate + L-alanine.,L-tyrosine:pyruvate transaminase activity,molecular_function
84458,GO:0080099,Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylsulfanyl-2-oxobutanoate + L-glutamate.,L-methionine:2-oxoglutarate transaminase activity,molecular_function
84459,GO:0080102,Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate.,3-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84460,GO:0080103,Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate.,4-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84461,GO:0080104,Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate.,5-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84462,GO:0080105,Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.,6-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84463,GO:0080106,Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.,7-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84464,GO:0080107,Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate.,8-methylthiopropyl glucosinolate S-oxygenase activity,molecular_function
84465,GO:0080108,Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.,S-alkylthiohydroximate lyase activity,molecular_function
84466,GO:0080109,Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide.,indole-3-acetonitrile nitrile hydratase activity,molecular_function
84467,GO:0080110,"The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.",sporopollenin biosynthetic process,biological_process
84468,GO:0080112,"The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo.",seed growth,biological_process
84469,GO:0080113,"Any process that modulates the frequency, rate or extent of growth of the seed of an plant.",regulation of seed growth,biological_process
84470,GO:0080115,Binding to the tail region of a myosin XI heavy chain.,myosin XI tail binding,molecular_function
84471,GO:0080116,Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.,glucuronoxylan glucuronosyltransferase activity,molecular_function
84472,GO:0080117,Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium.,secondary growth,biological_process
84473,GO:0080118,"Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.",brassinosteroid sulfotransferase activity,molecular_function
84474,GO:0080119,A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.,ER body organization,biological_process
84475,GO:0080120,"A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransfera...",CAAX-box protein maturation,biological_process
84476,GO:0080121,"The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",AMP transport,biological_process
84477,GO:0080122,"Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.",AMP transmembrane transporter activity,molecular_function
84478,GO:0080123,"Catalysis of the reaction: a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H+. In Arabidopsis, isoleucine is the principal amino acid that conjugates with JA to form JA (JA-Ile). Other amino acid can be conjugated with JA such as valine, leucine, and phenylalanine.",jasmonoyl-L-amino acid ligase activity,molecular_function
84479,GO:0080124,Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.,pheophytinase activity,molecular_function
84480,GO:0080126,"The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).",ovary septum development,biological_process
84481,GO:0080127,"The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit.",fruit septum development,biological_process
84482,GO:0080128,"The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone.",anther septum development,biological_process
84483,GO:0080129,"The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.",proteasome core complex assembly,biological_process
84484,GO:0080130,Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = 3-phenylpyruvate + L-glutamate.,L-phenylalanine:2-oxoglutarate transaminase activity,molecular_function
84485,GO:0080131,"Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.",hydroxyjasmonate sulfotransferase activity,molecular_function
84486,GO:0080132,Catalysis of the hydroxylation of the C-2 position in a fatty acid. The 2-hydroxylation may occur on free fatty acids or within the fatty acyl chain of a sphingolipid.,fatty acid 2-hydroxylase activity,molecular_function
84487,GO:0080133,Catalysis of the conversion of an alkane to a secondary alcohol.,midchain alkane hydroxylase activity,molecular_function
84488,GO:0080134,"Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",regulation of response to stress,biological_process
84489,GO:0080135,"Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",regulation of cellular response to stress,biological_process
84490,GO:0080136,The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress.,priming of cellular response to stress,biological_process
84491,GO:0080139,Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane.,borate efflux transmembrane transporter activity,molecular_function
84492,GO:0080140,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid.",regulation of jasmonic acid metabolic process,biological_process
84493,GO:0080141,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid.",regulation of jasmonic acid biosynthetic process,biological_process
84494,GO:0080142,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid.",regulation of salicylic acid biosynthetic process,biological_process
84495,GO:0080143,"Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.",regulation of amino acid export,biological_process
84496,GO:0080144,A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell.,intracellular amino acid homeostasis,biological_process
84497,GO:0080145,A homeostatic process involved in the maintenance of a steady state level of L-cysteine within a cell.,intracellular cysteine homeostasis,biological_process
84498,GO:0080146,Catalysis of the reaction: L-cysteine + H2O = hydrogen sulfide + pyruvate + NH4+ + H+.,L-cysteine desulfhydrase activity,molecular_function
84499,GO:0080147,"The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.",root hair cell development,biological_process
84500,GO:0080148,"Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.",negative regulation of response to water deprivation,biological_process
84501,GO:0080149,"Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level.",sucrose induced translational repression,biological_process
84502,GO:0080150,Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.,S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity,molecular_function
84503,GO:0080151,"Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.",positive regulation of salicylic acid mediated signaling pathway,biological_process
84504,GO:0080152,"Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.",regulation of reductive pentose-phosphate cycle,biological_process
84505,GO:0080153,"Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.",negative regulation of reductive pentose-phosphate cycle,biological_process
84506,GO:0080154,"Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).",regulation of fertilization,biological_process
84507,GO:0080155,"Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determi...",regulation of double fertilization forming a zygote and endosperm,biological_process
84508,GO:0080156,The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.,mitochondrial mRNA modification,biological_process
84509,GO:0080157,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.",regulation of plant-type cell wall organization or biogenesis,biological_process
84510,GO:0080159,The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana.,zygote elongation,biological_process
84511,GO:0080160,"The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",selenate transport,biological_process
84512,GO:0080161,Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.,auxin transmembrane transporter activity,molecular_function
84513,GO:0080162,The directed movement of auxins from endoplasmic reticulum to cytosol.,endoplasmic reticulum to cytosol auxin transport,biological_process
84514,GO:0080164,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.",regulation of nitric oxide metabolic process,biological_process
84515,GO:0080165,"Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.",callose deposition in phloem sieve plate,biological_process
84516,GO:0080166,"The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.",stomium development,biological_process
84517,GO:0080167,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).",response to karrikin,biological_process
84518,GO:0080168,"The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore.",abscisic acid transport,biological_process
84519,GO:0080169,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances.",cellular response to boron-containing substance deprivation,biological_process
84520,GO:0080170,The process in which H2O2 is transported across a membrane.,hydrogen peroxide transmembrane transport,biological_process
84521,GO:0080171,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.",lytic vacuole organization,biological_process
84522,GO:0080172,The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.,petal epidermis patterning,biological_process
84523,GO:0080173,The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.,male-female gamete recognition during double fertilization forming a zygote and endosperm,biological_process
84524,GO:0080175,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.",phragmoplast microtubule organization,biological_process
84525,GO:0080176,Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.,"xyloglucan 1,6-alpha-xylosidase activity",molecular_function
84526,GO:0080177,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.",plastoglobule organization,biological_process
84527,GO:0080178,The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA.,5-carbamoylmethyl uridine residue modification,biological_process
84528,GO:0080179,The chemical reactions and pathways involving 1-methylguanosine.,1-methylguanosine metabolic process,biological_process
84529,GO:0080180,The chemical reactions and pathways involving 2-methylguanosine.,2-methylguanosine metabolic process,biological_process
84530,GO:0080181,Any process involved in the formation of branches in lateral roots.,lateral root branching,biological_process
84531,GO:0080183,"Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.",response to photooxidative stress,biological_process
84532,GO:0080184,"Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumari...",response to phenylpropanoid,biological_process
84533,GO:0080185,"A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes).",effector-mediated activation of plant hypersensitive response by symbiont,biological_process
84534,GO:0080186,The increase in size or mass of non-reproductive plant parts.,developmental vegetative growth,biological_process
84535,GO:0080187,The last stage of flower development during which programmed degradation of macromolecules and nutrient recycling take place.,floral organ senescence,biological_process
84536,GO:0080188,"A small RNA-based gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltr...",gene silencing by siRNA-directed DNA methylation,biological_process
84537,GO:0080189,Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed.,primary growth,biological_process
84538,GO:0080190,Growth of a plant axis (shoot axis or root) that originates from a lateral meristem.,lateral growth,biological_process
84539,GO:0080191,Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.,secondary thickening,biological_process
84540,GO:0080192,Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem.,primary thickening,biological_process
84541,GO:0080193,"Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem.",diffuse secondary thickening,biological_process
84542,GO:0085001,"The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.",formation of stylet for nutrient acquisition,biological_process
84543,GO:0085014,Entry into a dormant state of the symbiont within the host organism.,dormancy entry of symbiont in host,biological_process
84544,GO:0085015,Any process in which a dormant state is maintained by the symbiont within the host organism.,dormancy maintenance of symbiont in host,biological_process
84545,GO:0085016,"Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.",dormancy exit of symbiont in host,biological_process
84546,GO:0085017,"The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.",entry into host cell by a symbiont-containing vacuole,biological_process
84547,GO:0085019,The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,formation of tubovesicular network for nutrient acquisition,biological_process
84548,GO:0085020,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.",protein K6-linked ubiquitination,biological_process
84549,GO:0085026,"A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains.",tubovesicular membrane network,cellular_component
84550,GO:0085029,"The aggregation, arrangement and bonding together of the extracellular matrix.",extracellular matrix assembly,biological_process
84551,GO:0085030,"A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism.",symbiotic process benefiting host,biological_process
84552,GO:0085032,A process in which a symbiont alters or subverts an NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host NF-kappaB cascade,biological_process
84553,GO:0085033,"A process that initiates, promotes, or enhances a host NF-kappaB-mediated signaling cascade. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host NF-kappaB cascade,biological_process
84554,GO:0085034,"A process in which a symbiont interferes with, inhibits or disrupts an NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host NF-kappaB cascade,biological_process
84555,GO:0085035,A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.,haustorium,cellular_component
84556,GO:0085036,The space between the symbiont plasma membrane and the extrahaustorial membrane of the host.,extrahaustorial matrix,cellular_component
84557,GO:0085037,"The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane.",extrahaustorial membrane,cellular_component
84558,GO:0085039,A host-derived membrane surrounding the symbiont hypha during infection.,hyphal membrane,cellular_component
84559,GO:0085041,"Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange.",arbuscule,cellular_component
84560,GO:0085042,A host-derived membrane surrounding the symbiont arbuscule during symbiosis.,periarbuscular membrane,cellular_component
84561,GO:0085044,The process in which an organism effects a change that impairs the structure or function of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cuticle,biological_process
84562,GO:0086001,An action potential that occurs in a cardiac muscle cell.,cardiac muscle cell action potential,biological_process
84563,GO:0086002,An action potential that occurs in a cardiac muscle cell and is involved in its contraction.,cardiac muscle cell action potential involved in contraction,biological_process
84564,GO:0086003,The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell.,cardiac muscle cell contraction,biological_process
84565,GO:0086004,"Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.",regulation of cardiac muscle cell contraction,biological_process
84566,GO:0086005,An action potential that occurs in a ventricular cardiac muscle cell.,ventricular cardiac muscle cell action potential,biological_process
84567,GO:0086006,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity involved in cardiac muscle cell action potential,molecular_function
84568,GO:0086007,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated calcium channel activity involved in cardiac muscle cell action potential,molecular_function
84569,GO:0086008,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization,molecular_function
84570,GO:0086009,"The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.",membrane repolarization,biological_process
84571,GO:0086010,The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during action potential,biological_process
84572,GO:0086011,The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during action potential,biological_process
84573,GO:0086012,The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during cardiac muscle cell action potential,biological_process
84574,GO:0086013,The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during cardiac muscle cell action potential,biological_process
84575,GO:0086014,An action potential that occurs in an atrial cardiac muscle cell.,atrial cardiac muscle cell action potential,biological_process
84576,GO:0086015,An action potential that occurs in a sinoatrial node cardiac muscle cell.,SA node cell action potential,biological_process
84577,GO:0086016,An action potential that occurs in an atrioventricular node cardiac muscle cell.,AV node cell action potential,biological_process
84578,GO:0086017,An action potential that occurs in a Purkinje myocyte.,Purkinje myocyte action potential,biological_process
84579,GO:0086018,Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.,SA node cell to atrial cardiac muscle cell signaling,biological_process
84580,GO:0086020,A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling,molecular_function
84581,GO:0086021,The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.,SA node cell to atrial cardiac muscle cell communication by electrical coupling,biological_process
84582,GO:0086023,"The series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.",adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process,biological_process
84583,GO:0086026,Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell.,atrial cardiac muscle cell to AV node cell signaling,biological_process
84584,GO:0086027,Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.,AV node cell to bundle of His cell signaling,biological_process
84585,GO:0086028,Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.,bundle of His cell to Purkinje myocyte signaling,biological_process
84586,GO:0086029,Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.,Purkinje myocyte to ventricular cardiac muscle cell signaling,biological_process
84587,GO:0086036,Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.,regulation of cardiac muscle cell membrane potential,biological_process
84588,GO:0086038,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.",calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential,molecular_function
84589,GO:0086039,A calcium-transporting P-type ATPase activity involved in regulation of the plasma membrane potential.,P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential,molecular_function
84590,GO:0086041,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in SA node cell action potential depolarization,molecular_function
84591,GO:0086042,The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.,cardiac muscle cell-cardiac muscle cell adhesion,biological_process
84592,GO:0086043,An action potential that occurs in a bundle of His cell.,bundle of His cell action potential,biological_process
84593,GO:0086044,The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.,atrial cardiac muscle cell to AV node cell communication by electrical coupling,biological_process
84594,GO:0086045,The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during AV node cell action potential,biological_process
84595,GO:0086046,The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during SA node cell action potential,biological_process
84596,GO:0086047,The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during Purkinje myocyte cell action potential,biological_process
84597,GO:0086048,The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during bundle of His cell action potential,biological_process
84598,GO:0086049,The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during AV node cell action potential,biological_process
84599,GO:0086050,The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during bundle of His cell action potential,biological_process
84600,GO:0086051,The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during Purkinje myocyte action potential,biological_process
84601,GO:0086052,The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during SA node cell action potential,biological_process
84602,GO:0086053,The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.,AV node cell to bundle of His cell communication by electrical coupling,biological_process
84603,GO:0086054,The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.,bundle of His cell to Purkinje myocyte communication by electrical coupling,biological_process
84604,GO:0086055,The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.,Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling,biological_process
84605,GO:0086056,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated calcium channel activity involved in AV node cell action potential,molecular_function
84606,GO:0086057,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated calcium channel activity involved in bundle of His cell action potential,molecular_function
84607,GO:0086059,Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated calcium channel activity involved SA node cell action potential,molecular_function
84608,GO:0086060,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity involved in AV node cell action potential,molecular_function
84609,GO:0086061,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity involved in bundle of His cell action potential,molecular_function
84610,GO:0086062,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity involved in Purkinje myocyte action potential,molecular_function
84611,GO:0086063,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated sodium channel activity involved in SA node cell action potential,molecular_function
84612,GO:0086064,The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.,cell communication by electrical coupling involved in cardiac conduction,biological_process
84613,GO:0086065,"Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",cell communication involved in cardiac conduction,biological_process
84614,GO:0086066,"The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",atrial cardiac muscle cell to AV node cell communication,biological_process
84615,GO:0086067,"The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",AV node cell to bundle of His cell communication,biological_process
84616,GO:0086068,"The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",Purkinje myocyte to ventricular cardiac muscle cell communication,biological_process
84617,GO:0086069,"The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",bundle of His cell to Purkinje myocyte communication,biological_process
84618,GO:0086070,"The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.",SA node cell to atrial cardiac muscle cell communication,biological_process
84619,GO:0086072,The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.,AV node cell-bundle of His cell adhesion involved in cell communication,biological_process
84620,GO:0086073,The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.,bundle of His cell-Purkinje myocyte adhesion involved in cell communication,biological_process
84621,GO:0086075,A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in cardiac conduction electrical coupling,molecular_function
84622,GO:0086076,A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling,molecular_function
84623,GO:0086077,A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling,molecular_function
84624,GO:0086078,A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling,molecular_function
84625,GO:0086079,A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.,gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling,molecular_function
84626,GO:0086080,Binding to a protein or protein complex contributing to the adhesion of two different types of cells.,protein binding involved in heterotypic cell-cell adhesion,molecular_function
84627,GO:0086082,Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.,cell adhesive protein binding involved in AV node cell-bundle of His cell communication,molecular_function
84628,GO:0086083,Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.,cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication,molecular_function
84629,GO:0086087,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization,molecular_function
84630,GO:0086089,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization,molecular_function
84631,GO:0086090,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in SA node cell action potential repolarization,molecular_function
84632,GO:0086091,A cardiac conduction process that modulates the frequency or rate of heart contraction.,regulation of heart rate by cardiac conduction,biological_process
84633,GO:0086092,"A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.",regulation of the force of heart contraction by cardiac conduction,biological_process
84634,GO:0086097,"A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by angiotensin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating angiotensin-activated signaling pathway,biological_process
84635,GO:0086098,An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.,angiotensin-activated signaling pathway involved in heart process,biological_process
84636,GO:0086100,"A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",endothelin receptor signaling pathway,biological_process
84637,GO:0086101,An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.,endothelin receptor signaling pathway involved in heart process,biological_process
84638,GO:0086103,An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.,G protein-coupled receptor signaling pathway involved in heart process,biological_process
84639,GO:0089701,A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.,U2AF complex,cellular_component
84640,GO:0089702,"Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose = alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP.",undecaprenyl-phosphate glucose phosphotransferase activity,molecular_function
84641,GO:0089703,"The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane.",L-aspartate transmembrane export from vacuole,biological_process
84642,GO:0089704,"The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.",L-glutamate transmembrane export from vacuole,biological_process
84643,GO:0089705,"A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.",protein localization to outer membrane,biological_process
84644,GO:0089706,"The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane.",L-ornithine transmembrane export from vacuole,biological_process
84645,GO:0089707,"The directed movement of L-lysine out of the vacuole, across the vacuolar membrane.",L-lysine transmembrane export from vacuole,biological_process
84646,GO:0089708,"The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.",L-histidine transmembrane export from vacuole,biological_process
84647,GO:0089709,The directed movement of L-histidine across a membrane.,L-histidine transmembrane transport,biological_process
84648,GO:0089710,"Binding to a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits.",endocytic targeting sequence binding,molecular_function
84649,GO:0089713,"A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.",Cbf1-Met4-Met28 complex,cellular_component
84650,GO:0089714,Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.,UDP-N-acetyl-D-mannosamine dehydrogenase activity,molecular_function
84651,GO:0089715,Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine at position 37 = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine at position 37.,tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity,molecular_function
84652,GO:0089716,"A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.",Pip2-Oaf1 complex,cellular_component
84653,GO:0089718,"The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.",amino acid import across plasma membrane,biological_process
84654,GO:0089719,Binding to an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif).,RHG protein domain binding,molecular_function
84655,GO:0089720,Binding to a caspase family protein.,caspase binding,molecular_function
84656,GO:0089721,Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other.,phosphoenolpyruvate transmembrane transporter activity,molecular_function
84657,GO:0089722,The directed movement of phosphoenolpytuvate across a membrane.,phosphoenolpyruvate transmembrane transport,biological_process
84658,GO:0090001,A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.,replication fork arrest at tRNA locus,biological_process
84659,GO:0090006,"Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.",regulation of linear element assembly,biological_process
84660,GO:0090008,"The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.",hypoblast development,biological_process
84661,GO:0090009,The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.,primitive streak formation,biological_process
84662,GO:0090014,The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf.,leaflet formation,biological_process
84663,GO:0090015,"Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.",positive regulation of leaflet formation by auxin mediated signaling pathway,biological_process
84664,GO:0090016,"Any process that modulates the frequency, rate or extent of leaflet formation.",regulation of leaflet formation,biological_process
84665,GO:0090017,"The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate.",anterior neural plate formation,biological_process
84666,GO:0090018,"The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.",posterior neural plate formation,biological_process
84667,GO:0090022,"Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.",regulation of neutrophil chemotaxis,biological_process
84668,GO:0090023,"Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.",positive regulation of neutrophil chemotaxis,biological_process
84669,GO:0090024,"Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.",negative regulation of neutrophil chemotaxis,biological_process
84670,GO:0090025,"Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.",regulation of monocyte chemotaxis,biological_process
84671,GO:0090026,"Any process that increases the frequency, rate, or extent of monocyte chemotaxis.",positive regulation of monocyte chemotaxis,biological_process
84672,GO:0090027,"Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.",negative regulation of monocyte chemotaxis,biological_process
84673,GO:0090030,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.",regulation of steroid hormone biosynthetic process,biological_process
84674,GO:0090031,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.",positive regulation of steroid hormone biosynthetic process,biological_process
84675,GO:0090032,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.",negative regulation of steroid hormone biosynthetic process,biological_process
84676,GO:0090033,"Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.",positive regulation of filamentous growth,biological_process
84677,GO:0090034,"Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.",regulation of chaperone-mediated protein complex assembly,biological_process
84678,GO:0090035,"Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.",positive regulation of chaperone-mediated protein complex assembly,biological_process
84679,GO:0090036,"Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.",regulation of protein kinase C signaling,biological_process
84680,GO:0090037,"Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.",positive regulation of protein kinase C signaling,biological_process
84681,GO:0090038,"Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.",negative regulation of protein kinase C signaling,biological_process
84682,GO:0090042,"The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",tubulin deacetylation,biological_process
84683,GO:0090043,"Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.",regulation of tubulin deacetylation,biological_process
84684,GO:0090044,"Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.",positive regulation of tubulin deacetylation,biological_process
84685,GO:0090045,"Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.",positive regulation of deacetylase activity,biological_process
84686,GO:0090049,"Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.",regulation of cell migration involved in sprouting angiogenesis,biological_process
84687,GO:0090050,"Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.",positive regulation of cell migration involved in sprouting angiogenesis,biological_process
84688,GO:0090051,"Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.",negative regulation of cell migration involved in sprouting angiogenesis,biological_process
84689,GO:0090052,"Any process that modulates the frequency, rate or extent of heterochromatin formation at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.",regulation of pericentric heterochromatin formation,biological_process
84690,GO:0090053,"Any process that increases the frequency, rate or extent of pericentric heterochromatin formation.",positive regulation of pericentric heterochromatin formation,biological_process
84691,GO:0090054,"Any process that modulates the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.",regulation of silent mating-type cassette heterochromatin formation,biological_process
84692,GO:0090055,"Any process that increases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.",positive regulation of silent mating-type cassette heterochromatin formation,biological_process
84693,GO:0090056,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll.",regulation of chlorophyll metabolic process,biological_process
84694,GO:0090057,The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.,root radial pattern formation,biological_process
84695,GO:0090058,"The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.",metaxylem development,biological_process
84696,GO:0090059,"The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem.",protoxylem development,biological_process
84697,GO:0090060,"Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.",regulation of metaxylem development,biological_process
84698,GO:0090062,"Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.",regulation of trehalose metabolic process,biological_process
84699,GO:0090063,"Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.",positive regulation of microtubule nucleation,biological_process
84700,GO:0090064,"Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.",activation of microtubule nucleation,biological_process
84701,GO:0090066,Any process that modulates the size of an anatomical structure.,regulation of anatomical structure size,biological_process
84702,GO:0090067,Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.,regulation of thalamus size,biological_process
84703,GO:0090068,"Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.",positive regulation of cell cycle process,biological_process
84704,GO:0090069,"Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.",regulation of ribosome biogenesis,biological_process
84705,GO:0090070,"Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.",positive regulation of ribosome biogenesis,biological_process
84706,GO:0090071,"Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.",negative regulation of ribosome biogenesis,biological_process
84707,GO:0090075,"A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.",relaxation of muscle,biological_process
84708,GO:0090076,A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.,relaxation of skeletal muscle,biological_process
84709,GO:0090077,"The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",foam cell differentiation,biological_process
84710,GO:0090078,"The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.",smooth muscle derived foam cell differentiation,biological_process
84711,GO:0090080,The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.,positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway,biological_process
84712,GO:0090083,"Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.",regulation of inclusion body assembly,biological_process
84713,GO:0090084,"Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.",negative regulation of inclusion body assembly,biological_process
84714,GO:0090085,"Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.",regulation of protein deubiquitination,biological_process
84715,GO:0090086,"Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.",negative regulation of protein deubiquitination,biological_process
84716,GO:0090087,"Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of peptide transport,biological_process
84717,GO:0090088,"Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.",regulation of oligopeptide transport,biological_process
84718,GO:0090089,"Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of dipeptide transport,biological_process
84719,GO:0090090,"Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.",negative regulation of canonical Wnt signaling pathway,biological_process
84720,GO:0090091,"Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.",positive regulation of extracellular matrix disassembly,biological_process
84721,GO:0090092,"Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.",regulation of transmembrane receptor protein serine/threonine kinase signaling pathway,biological_process
84722,GO:0090093,"Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.",regulation of fungal-type cell wall beta-glucan biosynthetic process,biological_process
84723,GO:0090094,"The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.",metanephric cap mesenchymal cell proliferation involved in metanephros development,biological_process
84724,GO:0090095,"Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.",regulation of metanephric cap mesenchymal cell proliferation,biological_process
84725,GO:0090096,"Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.",positive regulation of metanephric cap mesenchymal cell proliferation,biological_process
84726,GO:0090100,"Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.",positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway,biological_process
84727,GO:0090101,"Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.",negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway,biological_process
84728,GO:0090102,The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.,cochlea development,biological_process
84729,GO:0090103,The process in which the cochlea is generated and organized.,cochlea morphogenesis,biological_process
84730,GO:0090104,The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.,pancreatic epsilon cell differentiation,biological_process
84731,GO:0090105,"The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.",pancreatic E cell development,biological_process
84732,GO:0090106,The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.,pancreatic E cell fate commitment,biological_process
84733,GO:0090107,"Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.",regulation of high-density lipoprotein particle assembly,biological_process
84734,GO:0090108,"Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.",positive regulation of high-density lipoprotein particle assembly,biological_process
84735,GO:0090109,"Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.",regulation of cell-substrate junction assembly,biological_process
84736,GO:0090110,The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.,COPII-coated vesicle cargo loading,biological_process
84737,GO:0090111,"Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.",regulation of COPII vesicle uncoating,biological_process
84738,GO:0090112,"The process in which COPII vesicle coat proteins are disassembled, and released.",COPII vesicle uncoating,biological_process
84739,GO:0090114,"The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.",COPII-coated vesicle budding,biological_process
84740,GO:0090117,The directed movement of low-density lipoprotein particle from endosomes to lysosomes.,endosome to lysosome transport of low-density lipoprotein particle,biological_process
84741,GO:0090118,A receptor-mediated endocytosis process involved in intracellular cholesterol transport.,receptor-mediated endocytosis involved in cholesterol transport,biological_process
84742,GO:0090119,"The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.",vesicle-mediated cholesterol transport,biological_process
84743,GO:0090120,"The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.",lysosome to ER cholesterol transport,biological_process
84744,GO:0090122,The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.,cholesterol ester hydrolysis involved in cholesterol transport,biological_process
84745,GO:0090123,The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes.,lysosomal glycocalyx,cellular_component
84746,GO:0090125,The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.,cell-cell adhesion involved in synapse maturation,biological_process
84747,GO:0090126,"The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.",protein-containing complex assembly involved in synapse maturation,biological_process
84748,GO:0090127,Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.,positive regulation of synapse maturation by synaptic transmission,biological_process
84749,GO:0090128,"Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.",regulation of synapse maturation,biological_process
84750,GO:0090129,"Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.",positive regulation of synapse maturation,biological_process
84751,GO:0090130,The process in which the population of cells that make up a tissue undergo directed movement.,tissue migration,biological_process
84752,GO:0090131,The process in which the population of cells that make up a mesenchyme undergo directed movement.,mesenchyme migration,biological_process
84753,GO:0090132,The process in which the population of cells that make up an epithelium undergo directed movement.,epithelium migration,biological_process
84754,GO:0090133,The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.,mesendoderm migration,biological_process
84755,GO:0090134,The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.,cell migration involved in mesendoderm migration,biological_process
84756,GO:0090135,The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.,actin filament branching,biological_process
84757,GO:0090136,The attachment of an epithelial cell to another epithelial cell via adhesion molecules.,epithelial cell-cell adhesion,biological_process
84758,GO:0090138,"Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.",regulation of actin cytoskeleton organization by cell-cell adhesion,biological_process
84759,GO:0090139,"A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure.",mitochondrial chromosome packaging,biological_process
84760,GO:0090140,"Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.",regulation of mitochondrial fission,biological_process
84761,GO:0090141,"Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.",positive regulation of mitochondrial fission,biological_process
84762,GO:0090148,A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.,membrane fission,biological_process
84763,GO:0090149,A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.,mitochondrial membrane fission,biological_process
84764,GO:0090150,The directed movement of a protein to a specific location in a membrane.,establishment of protein localization to membrane,biological_process
84765,GO:0090153,"Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",regulation of sphingolipid biosynthetic process,biological_process
84766,GO:0090154,"Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",positive regulation of sphingolipid biosynthetic process,biological_process
84767,GO:0090155,"Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).",negative regulation of sphingolipid biosynthetic process,biological_process
84768,GO:0090156,A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell.,intracellular sphingolipid homeostasis,biological_process
84769,GO:0090158,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.",endoplasmic reticulum membrane organization,biological_process
84770,GO:0090160,The directed movement of substances from the Golgi to lysosomes.,Golgi to lysosome transport,biological_process
84771,GO:0090161,The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.,Golgi ribbon formation,biological_process
84772,GO:0090162,The specification and formation of anisotropic intracellular organization of an epithelial cell.,establishment of epithelial cell polarity,biological_process
84773,GO:0090163,The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.,establishment of epithelial cell planar polarity,biological_process
84774,GO:0090164,The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.,asymmetric Golgi ribbon formation,biological_process
84775,GO:0090165,The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell.,regulation of secretion by asymmetric Golgi ribbon formation,biological_process
84776,GO:0090166,A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.,Golgi disassembly,biological_process
84777,GO:0090167,Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division.,Golgi distribution to daughter cells,biological_process
84778,GO:0090168,The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.,Golgi reassembly,biological_process
84779,GO:0090169,"Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.",regulation of spindle assembly,biological_process
84780,GO:0090170,"Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.",regulation of Golgi inheritance,biological_process
84781,GO:0090171,The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.,chondrocyte morphogenesis,biological_process
84782,GO:0090173,"Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.",regulation of synaptonemal complex assembly,biological_process
84783,GO:0090174,The joining of two lipid bilayers to form a single organelle membrane.,organelle membrane fusion,biological_process
84784,GO:0090175,"Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.",regulation of establishment of planar polarity,biological_process
84785,GO:0090176,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.",microtubule cytoskeleton organization involved in establishment of planar polarity,biological_process
84786,GO:0090177,Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.,establishment of planar polarity involved in neural tube closure,biological_process
84787,GO:0090178,"Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.",regulation of establishment of planar polarity involved in neural tube closure,biological_process
84788,GO:0090180,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.",positive regulation of thiamine biosynthetic process,biological_process
84789,GO:0090181,"Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",regulation of cholesterol metabolic process,biological_process
84790,GO:0090182,"Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.",regulation of secretion of lysosomal enzymes,biological_process
84791,GO:0090183,"Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",regulation of kidney development,biological_process
84792,GO:0090184,"Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",positive regulation of kidney development,biological_process
84793,GO:0090185,"Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.",negative regulation of kidney development,biological_process
84794,GO:0090186,"Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.",regulation of pancreatic juice secretion,biological_process
84795,GO:0090187,"Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.",positive regulation of pancreatic juice secretion,biological_process
84796,GO:0090188,"Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.",negative regulation of pancreatic juice secretion,biological_process
84797,GO:0090189,"Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.",regulation of branching involved in ureteric bud morphogenesis,biological_process
84798,GO:0090190,"Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.",positive regulation of branching involved in ureteric bud morphogenesis,biological_process
84799,GO:0090191,"Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.",negative regulation of branching involved in ureteric bud morphogenesis,biological_process
84800,GO:0090192,"Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.",regulation of glomerulus development,biological_process
84801,GO:0090193,"Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.",positive regulation of glomerulus development,biological_process
84802,GO:0090194,"Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.",negative regulation of glomerulus development,biological_process
84803,GO:0090199,"Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.",regulation of release of cytochrome c from mitochondria,biological_process
84804,GO:0090200,"Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.",positive regulation of release of cytochrome c from mitochondria,biological_process
84805,GO:0090201,"Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.",negative regulation of release of cytochrome c from mitochondria,biological_process
84806,GO:0090204,"A process in which a protein is transported to, or maintained in, a nuclear pore.",protein localization to nuclear pore,biological_process
84807,GO:0090205,"Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",positive regulation of cholesterol metabolic process,biological_process
84808,GO:0090206,"Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.",negative regulation of cholesterol metabolic process,biological_process
84809,GO:0090207,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.",regulation of triglyceride metabolic process,biological_process
84810,GO:0090208,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.",positive regulation of triglyceride metabolic process,biological_process
84811,GO:0090209,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.",negative regulation of triglyceride metabolic process,biological_process
84812,GO:0090210,"Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.",regulation of establishment of blood-brain barrier,biological_process
84813,GO:0090211,"Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.",positive regulation of establishment of blood-brain barrier,biological_process
84814,GO:0090212,"Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.",negative regulation of establishment of blood-brain barrier,biological_process
84815,GO:0090213,"Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.",regulation of radial pattern formation,biological_process
84816,GO:0090214,The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.,spongiotrophoblast layer developmental growth,biological_process
84817,GO:0090218,"Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.",positive regulation of lipid kinase activity,biological_process
84818,GO:0090220,The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis.,chromosome localization to nuclear envelope involved in homologous chromosome segregation,biological_process
84819,GO:0090221,"The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.",mitotic spindle-templated microtubule nucleation,biological_process
84820,GO:0090222,"The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.",centrosome-templated microtubule nucleation,biological_process
84821,GO:0090223,"The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.",chromatin-templated microtubule nucleation,biological_process
84822,GO:0090224,"Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.",regulation of spindle organization,biological_process
84823,GO:0090227,"Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.",regulation of red or far-red light signaling pathway,biological_process
84824,GO:0090228,"Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.",positive regulation of red or far-red light signaling pathway,biological_process
84825,GO:0090229,"Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.",negative regulation of red or far-red light signaling pathway,biological_process
84826,GO:0090231,"Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.",regulation of spindle checkpoint,biological_process
84827,GO:0090232,"Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.",positive regulation of spindle checkpoint,biological_process
84828,GO:0090233,"Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.",negative regulation of spindle checkpoint,biological_process
84829,GO:0090234,"Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.",regulation of kinetochore assembly,biological_process
84830,GO:0090235,"Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.",regulation of metaphase plate congression,biological_process
84831,GO:0090237,"Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.",regulation of arachidonate secretion,biological_process
84832,GO:0090238,"Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.",positive regulation of arachidonate secretion,biological_process
84833,GO:0090243,The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.,fibroblast growth factor receptor signaling pathway involved in somitogenesis,biological_process
84834,GO:0090244,The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.,Wnt signaling pathway involved in somitogenesis,biological_process
84835,GO:0090245,The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.,axis elongation involved in somitogenesis,biological_process
84836,GO:0090246,The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.,convergent extension involved in somitogenesis,biological_process
84837,GO:0090248,Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.,cell migration involved in somitogenic axis elongation,biological_process
84838,GO:0090249,"Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.",regulation of cell migration involved in somitogenic axis elongation,biological_process
84839,GO:0090251,"Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.",protein localization involved in establishment of planar polarity,biological_process
84840,GO:0090254,The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.,cell elongation involved in imaginal disc-derived wing morphogenesis,biological_process
84841,GO:0090255,"The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.",cell proliferation involved in imaginal disc-derived wing morphogenesis,biological_process
84842,GO:0090256,"Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.",regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis,biological_process
84843,GO:0090257,"Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.",regulation of muscle system process,biological_process
84844,GO:0090258,"Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.",negative regulation of mitochondrial fission,biological_process
84845,GO:0090259,"Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.",regulation of retinal ganglion cell axon guidance,biological_process
84846,GO:0090260,"Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.",negative regulation of retinal ganglion cell axon guidance,biological_process
84847,GO:0090261,"Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.",positive regulation of inclusion body assembly,biological_process
84848,GO:0090262,"Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.",regulation of transcription-coupled nucleotide-excision repair,biological_process
84849,GO:0090263,"Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.",positive regulation of canonical Wnt signaling pathway,biological_process
84850,GO:0090264,"Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.",regulation of immune complex clearance by monocytes and macrophages,biological_process
84851,GO:0090265,"Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.",positive regulation of immune complex clearance by monocytes and macrophages,biological_process
84852,GO:0090266,"Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.",regulation of mitotic cell cycle spindle assembly checkpoint,biological_process
84853,GO:0090267,"Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.",positive regulation of mitotic cell cycle spindle assembly checkpoint,biological_process
84854,GO:0090268,Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.,activation of mitotic cell cycle spindle assembly checkpoint,biological_process
84855,GO:0090269,"The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",fibroblast growth factor production,biological_process
84856,GO:0090270,"Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",regulation of fibroblast growth factor production,biological_process
84857,GO:0090271,"Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",positive regulation of fibroblast growth factor production,biological_process
84858,GO:0090272,"Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",negative regulation of fibroblast growth factor production,biological_process
84859,GO:0090273,"Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.",regulation of somatostatin secretion,biological_process
84860,GO:0090274,"Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.",positive regulation of somatostatin secretion,biological_process
84861,GO:0090275,"Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.",negative regulation of somatostatin secretion,biological_process
84862,GO:0090276,"Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.",regulation of peptide hormone secretion,biological_process
84863,GO:0090277,"Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.",positive regulation of peptide hormone secretion,biological_process
84864,GO:0090278,"Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.",negative regulation of peptide hormone secretion,biological_process
84865,GO:0090279,"Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.",regulation of calcium ion import,biological_process
84866,GO:0090280,"Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.",positive regulation of calcium ion import,biological_process
84867,GO:0090281,"Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.",negative regulation of calcium ion import,biological_process
84868,GO:0090287,"Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.",regulation of cellular response to growth factor stimulus,biological_process
84869,GO:0090288,"Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.",negative regulation of cellular response to growth factor stimulus,biological_process
84870,GO:0090289,"Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.",regulation of osteoclast proliferation,biological_process
84871,GO:0090290,"Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.",positive regulation of osteoclast proliferation,biological_process
84872,GO:0090291,"Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.",negative regulation of osteoclast proliferation,biological_process
84873,GO:0090292,"The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.",nuclear matrix anchoring at nuclear membrane,biological_process
84874,GO:0090293,"A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.",nitrogen catabolite regulation of transcription,biological_process
84875,GO:0090294,"A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.",nitrogen catabolite activation of transcription,biological_process
84876,GO:0090295,"A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.",nitrogen catabolite repression of transcription,biological_process
84877,GO:0090296,"Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.",regulation of mitochondrial DNA replication,biological_process
84878,GO:0090297,"Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.",positive regulation of mitochondrial DNA replication,biological_process
84879,GO:0090298,"Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.",negative regulation of mitochondrial DNA replication,biological_process
84880,GO:0090299,"Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.",regulation of neural crest formation,biological_process
84881,GO:0090300,"Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.",positive regulation of neural crest formation,biological_process
84882,GO:0090301,"Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.",negative regulation of neural crest formation,biological_process
84883,GO:0090303,"Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.",positive regulation of wound healing,biological_process
84884,GO:0090304,Any cellular metabolic process involving nucleic acids.,nucleic acid metabolic process,biological_process
84885,GO:0090306,"The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.",meiotic spindle assembly,biological_process
84886,GO:0090307,"Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.",mitotic spindle assembly,biological_process
84887,GO:0090310,"Any process that decreases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation.",negative regulation of DNA methylation-dependent heterochromatin formation,biological_process
84888,GO:0090311,"Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",regulation of protein deacetylation,biological_process
84889,GO:0090312,"Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",positive regulation of protein deacetylation,biological_process
84890,GO:0090313,"Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.",regulation of protein targeting to membrane,biological_process
84891,GO:0090314,"Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.",positive regulation of protein targeting to membrane,biological_process
84892,GO:0090315,"Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.",negative regulation of protein targeting to membrane,biological_process
84893,GO:0090316,"Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.",positive regulation of intracellular protein transport,biological_process
84894,GO:0090317,"Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.",negative regulation of intracellular protein transport,biological_process
84895,GO:0090318,"Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.",regulation of chylomicron remodeling,biological_process
84896,GO:0090319,"Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.",positive regulation of chylomicron remodeling,biological_process
84897,GO:0090320,"Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.",regulation of chylomicron remnant clearance,biological_process
84898,GO:0090321,"Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.",positive regulation of chylomicron remnant clearance,biological_process
84899,GO:0090322,"Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.",regulation of superoxide metabolic process,biological_process
84900,GO:0090324,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.",negative regulation of oxidative phosphorylation,biological_process
84901,GO:0090325,"Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.",regulation of locomotion involved in locomotory behavior,biological_process
84902,GO:0090326,"Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.",positive regulation of locomotion involved in locomotory behavior,biological_process
84903,GO:0090327,"Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.",negative regulation of locomotion involved in locomotory behavior,biological_process
84904,GO:0090328,"Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.",regulation of olfactory learning,biological_process
84905,GO:0090329,"Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.",regulation of DNA-templated DNA replication,biological_process
84906,GO:0090330,"Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.",regulation of platelet aggregation,biological_process
84907,GO:0090331,"Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.",negative regulation of platelet aggregation,biological_process
84908,GO:0090332,"The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.",stomatal closure,biological_process
84909,GO:0090333,"Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.",regulation of stomatal closure,biological_process
84910,GO:0090334,"Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.",regulation of cell wall (1->3)-beta-D-glucan biosynthetic process,biological_process
84911,GO:0090335,"Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.",regulation of brown fat cell differentiation,biological_process
84912,GO:0090336,"Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.",positive regulation of brown fat cell differentiation,biological_process
84913,GO:0090337,"Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.",regulation of formin-nucleated actin cable assembly,biological_process
84914,GO:0090338,"Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.",positive regulation of formin-nucleated actin cable assembly,biological_process
84915,GO:0090339,"Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.",negative regulation of formin-nucleated actin cable assembly,biological_process
84916,GO:0090340,"Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.",positive regulation of secretion of lysosomal enzymes,biological_process
84917,GO:0090341,"Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.",negative regulation of secretion of lysosomal enzymes,biological_process
84918,GO:0090345,"The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.",organohalogen metabolic process,biological_process
84919,GO:0090346,"The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.",organofluorine metabolic process,biological_process
84920,GO:0090347,"Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.",regulation of organohalogen metabolic process,biological_process
84921,GO:0090350,"Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.",negative regulation of organofluorine metabolic process,biological_process
84922,GO:0090351,"The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.",seedling development,biological_process
84923,GO:0090352,"Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.",regulation of nitrate assimilation,biological_process
84924,GO:0090353,"Binds to and stops, prevents or reduces the activity of polygalacturonase.",polygalacturonase inhibitor activity,molecular_function
84925,GO:0090354,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.",regulation of auxin metabolic process,biological_process
84926,GO:0090355,"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.",positive regulation of auxin metabolic process,biological_process
84927,GO:0090356,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.",negative regulation of auxin metabolic process,biological_process
84928,GO:0090359,"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.",negative regulation of abscisic acid biosynthetic process,biological_process
84929,GO:0090360,"The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",platelet-derived growth factor production,biological_process
84930,GO:0090361,"Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",regulation of platelet-derived growth factor production,biological_process
84931,GO:0090362,"Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",positive regulation of platelet-derived growth factor production,biological_process
84932,GO:0090364,"Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.",regulation of proteasome assembly,biological_process
84933,GO:0090365,"Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.",regulation of mRNA modification,biological_process
84934,GO:0090366,"Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.",positive regulation of mRNA modification,biological_process
84935,GO:0090367,"Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.",negative regulation of mRNA modification,biological_process
84936,GO:0090369,"Binds to and stops, prevents, or reduces the activity of ornithine carbamoyltransferase.",ornithine carbamoyltransferase inhibitor activity,molecular_function
84937,GO:0090370,"Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.",negative regulation of cholesterol efflux,biological_process
84938,GO:0090371,"Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",regulation of glycerol transport,biological_process
84939,GO:0090372,"Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",positive regulation of glycerol transport,biological_process
84940,GO:0090373,"Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",negative regulation of glycerol transport,biological_process
84941,GO:0090374,The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.,oligopeptide export from mitochondrion,biological_process
84942,GO:0090376,The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.,seed trichome differentiation,biological_process
84943,GO:0090377,"The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.",seed trichome initiation,biological_process
84944,GO:0090378,"The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.",seed trichome elongation,biological_process
84945,GO:0090379,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.",secondary cell wall biogenesis involved in seed trichome differentiation,biological_process
84946,GO:0090380,"A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.",seed trichome maturation,biological_process
84947,GO:0090381,"Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.",regulation of heart induction,biological_process
84948,GO:0090382,"A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.",phagosome maturation,biological_process
84949,GO:0090383,"Any process that reduces the pH of the phagosome, corresponding to an increase in hydrogen ion concentration.",phagosome acidification,biological_process
84950,GO:0090385,The creation of a phagolysosome from a phagosome and a lysosome.,phagosome-lysosome fusion,biological_process
84951,GO:0090386,"A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.",phagosome maturation involved in apoptotic cell clearance,biological_process
84952,GO:0090387,"The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.",phagolysosome assembly involved in apoptotic cell clearance,biological_process
84953,GO:0090389,The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance.,phagosome-lysosome fusion involved in apoptotic cell clearance,biological_process
84954,GO:0090390,"Any process that reduces the pH of the phagosome, corresponding to an increase in hydrogen ion concentration, and occurs as a part of apoptotic cell clearance.",phagosome acidification involved in apoptotic cell clearance,biological_process
84955,GO:0090391,A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts.,granum assembly,biological_process
84956,GO:0090392,The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.,sepal giant cell differentiation,biological_process
84957,GO:0090393,"The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",sepal giant cell development,biological_process
84958,GO:0090394,Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.,negative regulation of excitatory postsynaptic potential,biological_process
84959,GO:0090395,"A cell projection that is a short, rounded projection from a plant epidermal cell.",plant cell papilla,cellular_component
84960,GO:0090396,A plant cell papilla that is part of a leaf papilla cell.,leaf papilla,cellular_component
84961,GO:0090397,A plant cell papilla that is part of a stigma papilla cell.,stigma papilla,cellular_component
84962,GO:0090398,"A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.",cellular senescence,biological_process
84963,GO:0090399,"The process by which normal somatic cells reach an irreversible stage of cell cycle arrest following multiple rounds of replication; this end stage is associated with marked changes in gene expression and function. This is a natural barrier to unlimited proliferation of somatic cells, and is believed to be contolled by telomere shortening.",replicative senescence,biological_process
84964,GO:0090400,A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.,stress-induced premature senescence,biological_process
84965,GO:0090402,"A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.",oncogene-induced cell senescence,biological_process
84966,GO:0090403,"A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.",oxidative stress-induced premature senescence,biological_process
84967,GO:0090404,"The region at growing end of the pollen tube cell, where polarized growth occurs.",pollen tube tip,cellular_component
84968,GO:0090405,A cell projection part that is a branch of a unicellular trichome.,unicellular trichome branch,cellular_component
84969,GO:0090406,A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.,pollen tube,cellular_component
84970,GO:0090407,"The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.",organophosphate biosynthetic process,biological_process
84971,GO:0090408,The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink.,phloem nitrate loading,biological_process
84972,GO:0090409,Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate.,malonyl-CoA synthetase activity,molecular_function
84973,GO:0090410,"The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.",malonate catabolic process,biological_process
84974,GO:0090411,Binding to a brassinosteroid.,brassinosteroid binding,molecular_function
84975,GO:0090414,The directed movement of molybdate ions out of the vacuole.,molybdate ion export from vacuole,biological_process
84976,GO:0090415,Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O.,7-hydroxymethyl chlorophyll a reductase activity,molecular_function
84977,GO:0090416,Enables the transfer of nicotinate from one side of a membrane to the other.,nicotinate transmembrane transporter activity,molecular_function
84978,GO:0090417,Enables the transfer of N-methylnicotinate from one side of a membrane to the other.,N-methylnicotinate transmembrane transporter activity,molecular_function
84979,GO:0090421,Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.,embryonic meristem initiation,biological_process
84980,GO:0090422,Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.,thiamine pyrophosphate transmembrane transporter activity,molecular_function
84981,GO:0090423,A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.,phytochelatin-metal complex formation,biological_process
84982,GO:0090424,A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.,phytochelatin-metal-sulfur complex formation,biological_process
84983,GO:0090425,"The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.",acinar cell differentiation,biological_process
84984,GO:0090426,A process of actin filament bundle distribution that results in the compaction of actin filaments.,actin filament bundle convergence,biological_process
84985,GO:0090427,Any process that starts the inactive process of meiosis.,activation of meiosis,biological_process
84986,GO:0090428,"The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.",perianth development,biological_process
84987,GO:0090430,Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.,caffeoyl-CoA: alcohol caffeoyl transferase activity,molecular_function
84988,GO:0090431,The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate.,alkyl caffeate ester biosynthetic process,biological_process
84989,GO:0090432,Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA.,myristoyl-CoA ligase activity,molecular_function
84990,GO:0090433,Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.,palmitoyl-CoA ligase activity,molecular_function
84991,GO:0090434,Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA.,oleoyl-CoA ligase activity,molecular_function
84992,GO:0090435,"A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.",protein localization to nuclear envelope,biological_process
84993,GO:0090436,"The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.",leaf pavement cell development,biological_process
84994,GO:0090437,"The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support.",socket cell differentiation,biological_process
84995,GO:0090438,"Catalyzes the reaction: (S)-2,3-epoxysqualene = camelliol C.",camelliol C synthase activity,molecular_function
84996,GO:0090439,Catalyzes the reaction: 7-hydroxylauroyl-CoA + 3 malonyl-CoA + 2 H+ = 2-(8-hydroxy-2-oxotridecyl)-6-oxopyran-4-olate + 3 CO2 + 4 coenzyme A.,tetraketide alpha-pyrone synthase activity,molecular_function
84997,GO:0090440,Enables the transfer of abscisic acid from one side of a membrane to the other.,abscisic acid transmembrane transporter activity,molecular_function
84998,GO:0090443,"A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body.",FAR/SIP/STRIPAK complex,cellular_component
84999,GO:0090444,Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.,"regulation of nematode larval development, heterochronic",biological_process
85000,GO:0090445,Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.,"positive regulation of nematode larval development, heterochronic",biological_process
85001,GO:0090446,Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.,"negative regulation of nematode larval development, heterochronic",biological_process
85002,GO:0090447,Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.,glycerol-3-phosphate 2-O-acyltransferase activity,molecular_function
85003,GO:0090448,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).,glucosinolate:proton symporter activity,molecular_function
85004,GO:0090449,The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.,phloem glucosinolate loading,biological_process
85005,GO:0090451,The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.,cotyledon boundary formation,biological_process
85006,GO:0090452,The directed movement of lithium ions (Li+) across a membrane.,lithium ion transmembrane transport,biological_process
85007,GO:0090453,The directed movement of aspartate into the vacuole across the vacuolar membrane.,aspartate transmembrane import into vacuole,biological_process
85008,GO:0090454,The directed movement of glutamate into the vacuole across the vacuolar membrane.,glutamate transmembrane import into vacuole,biological_process
85009,GO:0090455,The directed movement of ornithine into the vacuole across the vacuolar membrane.,ornithine transmembrane import into vacuole,biological_process
85010,GO:0090459,A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell.,intracellular aspartate homeostasis,biological_process
85011,GO:0090460,A homeostatic process involved in the maintenance of a steady state level of threonine within a cell.,intracellular threonine homeostasis,biological_process
85012,GO:0090461,A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell.,intracellular glutamate homeostasis,biological_process
85013,GO:0090462,A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell.,intracellular ornithine homeostasis,biological_process
85014,GO:0090463,A homeostatic process involved in the maintenance of a steady state level of lysine within a cell.,intracellular lysine homeostasis,biological_process
85015,GO:0090464,A homeostatic process involved in the maintenance of a steady state level of histidine within a cell.,intracellular histidine homeostasis,biological_process
85016,GO:0090465,A homeostatic process involved in the maintenance of a steady state level of arginine within a cell.,intracellular arginine homeostasis,biological_process
85017,GO:0090470,The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.,shoot organ boundary specification,biological_process
85018,GO:0090471,"Catalysis of the reaction: 9,9',15-tri-cis-zeta-carotene = 9,9'-di-cis-zeta-carotene.","9,15,9'-tri-cis-zeta-carotene isomerase activity",molecular_function
85019,GO:0090472,Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.,dibasic protein processing,biological_process
85020,GO:0090473,Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein.,lys-arg specific dibasic protein processing,biological_process
85021,GO:0090474,Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.,arg-arg specific dibasic protein processing,biological_process
85022,GO:0090475,Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein.,lys-lys specific dibasic protein processing,biological_process
85023,GO:0090480,The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.,purine nucleotide-sugar transmembrane transport,biological_process
85024,GO:0090481,The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.,pyrimidine nucleotide-sugar transmembrane transport,biological_process
85025,GO:0090482,Enables the transfer of a vitamin from one side of a membrane to the other.,vitamin transmembrane transporter activity,molecular_function
85026,GO:0090483,Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.,phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity,molecular_function
85027,GO:0090486,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA = S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.,small RNA 2'-O-ribose methyltransferase activity,molecular_function
85028,GO:0090487,"The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.",secondary metabolite catabolic process,biological_process
85029,GO:0090488,Binding to a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases.,polo box domain specific binding,molecular_function
85030,GO:0090489,Catalyzes the multi-step reaction: L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H+ + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].,tryptophan N-monooxygenase activity,molecular_function
85031,GO:0090493,The directed movement of catecholamine into a cell.,catecholamine uptake,biological_process
85032,GO:0090494,The directed movement of dopamine into a cell.,dopamine uptake,biological_process
85033,GO:0090495,The disaggregation of a low-density lipoprotein particle into its constituent components.,low-density lipoprotein particle disassembly,biological_process
85034,GO:0090497,"The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.",mesenchymal cell migration,biological_process
85035,GO:0090498,"The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of Golgi membrane,cellular_component
85036,GO:0090499,Catalysis of the reaction: 6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H+ + methanol.,pimelyl-[acyl-carrier protein] methyl ester esterase activity,molecular_function
85037,GO:0090500,"A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.",endocardial cushion to mesenchymal transition,biological_process
85038,GO:0090504,The expansion of one cell sheet over other cells or yolk.,epiboly,biological_process
85039,GO:0090505,The expansion of one cell sheet over other cells involved in wound healing.,epiboly involved in wound healing,biological_process
85040,GO:0090506,A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf.,axillary shoot meristem initiation,biological_process
85041,GO:0090510,A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file.,anticlinal cell division,biological_process
85042,GO:0090511,A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file.,periclinal cell division,biological_process
85043,GO:0090512,A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins.,eisosome membrane domain/MCC,cellular_component
85044,GO:0090513,The directed movement of L-histidine into the vacuole across the vacuolar membrane.,L-histidine transmembrane import into vacuole,biological_process
85045,GO:0090514,The directed movement of L-tyrosine into the vacuole across the vacuolar membrane.,L-tyrosine transmembrane import into vacuole,biological_process
85046,GO:0090515,The directed movement of L-glutamate into the vacuole across the vacuolar membrane.,L-glutamate transmembrane import into vacuole,biological_process
85047,GO:0090516,The directed movement of L-serine into the vacuole across the vacuolar membrane.,L-serine transmembrane import into vacuole,biological_process
85048,GO:0090517,The directed movement of L-lysine into the vacuole across the vacuolar membrane.,L-lysine transmembrane import into vacuole,biological_process
85049,GO:0090518,The directed movement of L-arginine into the vacuole across the vacuolar membrane.,L-arginine transmembrane import into vacuole,biological_process
85050,GO:0090519,"Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia.",anoxia protection,biological_process
85051,GO:0090520,The series of molecular signals mediated by a sphingolipid.,sphingolipid mediated signaling pathway,biological_process
85052,GO:0090521,"The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.",podocyte cell migration,biological_process
85053,GO:0090523,Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NADPH = 2 Fe(II)-[cytochrome b5] + NADP+ + H+.,"cytochrome-b5 reductase activity, acting on NADPH",molecular_function
85054,GO:0090524,Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD+ + H+.,"cytochrome-b5 reductase activity, acting on NADH",molecular_function
85055,GO:0090528,"The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.",smooth septate junction assembly,biological_process
85056,GO:0090529,The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.,cell septum assembly,biological_process
85057,GO:0090533,Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).,cation-transporting ATPase complex,cellular_component
85058,GO:0090534,Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).,calcium ion-transporting ATPase complex,cellular_component
85059,GO:0090535,"An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.",WICH complex,cellular_component
85060,GO:0090536,"An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.",NoRC complex,cellular_component
85061,GO:0090537,"An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.",CERF complex,cellular_component
85062,GO:0090538,The regulated release of a peptide pheromone from a cell.,peptide pheromone secretion,biological_process
85063,GO:0090539,The directed movement of a peptide pheromone across a membrane and out of a cell.,peptide pheromone export by transmembrane transport,biological_process
85064,GO:0090540,"The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.",bacterial cellulose biosynthetic process,biological_process
85065,GO:0090541,"Binding to a MIT protein domain. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.",MIT domain binding,molecular_function
85066,GO:0090542,"Binding to a ELYC protein domain. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC.",ELYC domain binding,molecular_function
85067,GO:0090543,A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.,Flemming body,cellular_component
85068,GO:0090545,"A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure.",CHD-type complex,cellular_component
85069,GO:0090546,The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light.,chlorophyll fluorescence,biological_process
85070,GO:0090547,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere.",response to low humidity,biological_process
85071,GO:0090548,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.",response to nitrate starvation,biological_process
85072,GO:0090549,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source.",response to carbon starvation,biological_process
85073,GO:0090550,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.",response to molybdenum starvation,biological_process
85074,GO:0090551,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.",response to manganese ion starvation,biological_process
85075,GO:0090552,A cell projection part that is the apical most portion of a unicellular trichome.,unicellular trichome apex,cellular_component
85076,GO:0090553,A cell projection part that is the apical most portion of a unicellular trichome apex.,unicellular trichome tip,cellular_component
85077,GO:0090554,"Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylcholine floppase activity,molecular_function
85078,GO:0090555,"Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylethanolamine flippase activity,molecular_function
85079,GO:0090556,"Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylserine floppase activity,molecular_function
85080,GO:0090557,"The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.",establishment of endothelial intestinal barrier,biological_process
85081,GO:0090558,"The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.",plant epidermis development,biological_process
85082,GO:0090559,"Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.",regulation of membrane permeability,biological_process
85083,GO:0090560,Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].,2-(3-amino-3-carboxypropyl)histidine synthase activity,molecular_function
85084,GO:0090561,"The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.",nuclear migration during mitotic telophase,biological_process
85085,GO:0090562,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).","protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity",molecular_function
85086,GO:0090563,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-phosphocysteine-sugar phosphotransferase activity,molecular_function
85087,GO:0090564,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-phosphocysteine-glucose phosphotransferase system transporter activity,molecular_function
85088,GO:0090565,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.",protein-phosphocysteine-mannitol phosphotransferase system transporter activity,molecular_function
85089,GO:0090566,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).","protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity",molecular_function
85090,GO:0090567,"The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.",reproductive shoot system development,biological_process
85091,GO:0090570,"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.",RNA polymerase I transcription repressor complex,cellular_component
85092,GO:0090571,"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter.",RNA polymerase II transcription repressor complex,cellular_component
85093,GO:0090572,"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.",RNA polymerase III transcription repressor complex,cellular_component
85094,GO:0090573,"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.",RNA polymerase IV transcription repressor complex,cellular_component
85095,GO:0090574,"A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.",RNA polymerase V transcription repressor complex,cellular_component
85096,GO:0090575,A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.,RNA polymerase II transcription regulator complex,cellular_component
85097,GO:0090576,A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.,RNA polymerase III transcription regulator complex,cellular_component
85098,GO:0090577,A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.,RNA polymerase IV transcription regulator complex,cellular_component
85099,GO:0090578,A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.,RNA polymerase V transcription regulator complex,cellular_component
85100,GO:0090580,Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.,"phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands",molecular_function
85101,GO:0090581,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).",protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity,molecular_function
85102,GO:0090582,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).",protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity,molecular_function
85103,GO:0090583,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in).",protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity,molecular_function
85104,GO:0090584,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).",protein-phosphocysteine-galactitol-phosphotransferase system transporter activity,molecular_function
85105,GO:0090585,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).",protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity,molecular_function
85106,GO:0090586,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).",protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity,molecular_function
85107,GO:0090587,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).",protein-phosphocysteine-glucosamine phosphotransferase system transporter activity,molecular_function
85108,GO:0090588,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).",protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity,molecular_function
85109,GO:0090589,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).",protein-phosphocysteine-trehalose phosphotransferase system transporter activity,molecular_function
85110,GO:0090591,"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in).",protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity,molecular_function
85111,GO:0090592,Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.,DNA synthesis involved in DNA replication,biological_process
85112,GO:0090594,The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.,inflammatory response to wounding,biological_process
85113,GO:0090595,Catalysis of the reaction: acetyl-CoA + L-lysine = CoA + H+ + N6-acetyl-L-lysine.,L-lysine N6-acetyltransferase activity,molecular_function
85114,GO:0090596,"Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",sensory organ morphogenesis,biological_process
85115,GO:0090597,"The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.",nematode male tail mating organ morphogenesis,biological_process
85116,GO:0090598,The processes by which anatomical structures that are only present in the male organism are generated and organized.,male anatomical structure morphogenesis,biological_process
85117,GO:0090599,"Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.",alpha-glucosidase activity,molecular_function
85118,GO:0090601,The process in which nucleated precursor cells lose their nucleus.,enucleation,biological_process
85119,GO:0090602,The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.,sieve element enucleation,biological_process
85120,GO:0090603,The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.,sieve element differentiation,biological_process
85121,GO:0090604,"A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",surface biofilm formation,biological_process
85122,GO:0090605,"A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",submerged biofilm formation,biological_process
85123,GO:0090606,A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.,single-species surface biofilm formation,biological_process
85124,GO:0090609,"A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.",single-species submerged biofilm formation,biological_process
85125,GO:0090610,"The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.",bundle sheath cell fate specification,biological_process
85126,GO:0090612,"Catalysis of the reaction: 3',5'-cyclic AMP + H2O + H+ = 3',5'-cyclic IMP + NH4+.",cAMP deaminase activity,molecular_function
85127,GO:0090613,Catalysis of the reaction: 5'-deoxyadenosine + H2O + H+ = 5'-deoxyinosine + NH4+.,5'-deoxyadenosine deaminase activity,molecular_function
85128,GO:0090614,Catalysis of the reaction: S-methyl-5'-thioadenosine + H2O + H+ = S-methyl-5'-thioinosine + NH4+.,5'-methylthioadenosine deaminase activity,molecular_function
85129,GO:0090615,Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.,mitochondrial mRNA processing,biological_process
85130,GO:0090616,Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.,mitochondrial mRNA 3'-end processing,biological_process
85131,GO:0090617,Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.,mitochondrial mRNA 5'-end processing,biological_process
85132,GO:0090619,"Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.",meiotic spindle pole,cellular_component
85133,GO:0090624,Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.,"endoribonuclease activity, cleaving miRNA-paired mRNA",molecular_function
85134,GO:0090625,"An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.",siRNA-mediated gene silencing by mRNA destabilization,biological_process
85135,GO:0090626,The process in which the anatomical structures of the plant epidermis are generated and organized.,plant epidermis morphogenesis,biological_process
85136,GO:0090627,The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.,plant epidermal cell differentiation,biological_process
85137,GO:0090628,"The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",plant epidermal cell fate specification,biological_process
85138,GO:0090629,The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.,lagging strand initiation,biological_process
85139,GO:0090630,Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.,activation of GTPase activity,biological_process
85140,GO:0090632,Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.,N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity,molecular_function
85141,GO:0090633,Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.,keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity,molecular_function
85142,GO:0090634,The directed killing of a target cell by a microglial cell.,microglial cell mediated cytotoxicity,biological_process
85143,GO:0090635,"The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.",extracellular core region of desmosome,cellular_component
85144,GO:0090636,"The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.",outer dense plaque of desmosome,cellular_component
85145,GO:0090637,"The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.",inner dense plaque of desmosome,cellular_component
85146,GO:0090641,"The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.",microsporidian-type endospore,cellular_component
85147,GO:0090642,"The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.",microsporidian-type exospore,cellular_component
85148,GO:0090643,The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.,inflorescence phyllotactic patterning,biological_process
85149,GO:0090644,"An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).",age-related resistance,biological_process
85150,GO:0090646,"The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.",mitochondrial tRNA processing,biological_process
85151,GO:0090648,"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.",response to environmental enrichment,biological_process
85152,GO:0090649,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.",response to oxygen-glucose deprivation,biological_process
85153,GO:0090650,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.",cellular response to oxygen-glucose deprivation,biological_process
85154,GO:0090651,The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.,apical cytoplasm,cellular_component
85155,GO:0090652,The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.,basolateral cytoplasm,cellular_component
85156,GO:0090653,Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.,apical recycling endosome,cellular_component
85157,GO:0090654,Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.,basolateral recycling endosome,cellular_component
85158,GO:0090655,Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.,double-stranded/single-stranded junction telomeric DNA binding,molecular_function
85159,GO:0090656,"A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).",t-circle formation,biological_process
85160,GO:0090657,The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.,telomeric loop disassembly,biological_process
85161,GO:0090658,A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.,cone matrix sheath,cellular_component
85162,GO:0090659,The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.,walking behavior,biological_process
85163,GO:0090660,"The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.",cerebrospinal fluid circulation,biological_process
85164,GO:0090661,"A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.",box H/ACA telomerase RNP complex,cellular_component
85165,GO:0090663,The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.,galanin-activated signaling pathway,biological_process
85166,GO:0090664,"Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.",response to high population density,biological_process
85167,GO:0090665,"A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.",glycoprotein complex,cellular_component
85168,GO:0090666,"A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.",scaRNA localization to Cajal body,biological_process
85169,GO:0090667,The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).,cell chemotaxis to vascular endothelial growth factor,biological_process
85170,GO:0090668,The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).,endothelial cell chemotaxis to vascular endothelial growth factor,biological_process
85171,GO:0090669,Prevention of degradation of telomerase RNA (TERC) molecules.,telomerase RNA stabilization,biological_process
85172,GO:0090670,"A process in which an RNA is transported to, or maintained in, a Cajal body.",RNA localization to Cajal body,biological_process
85173,GO:0090671,"A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.",telomerase RNA localization to Cajal body,biological_process
85174,GO:0090672,"Any process in which telomerase RNA is transported to, or maintained in, a specific location.",telomerase RNA localization,biological_process
85175,GO:0090673,The binding of an endothelial cell to the extracellular matrix via adhesion molecules.,endothelial cell-matrix adhesion,biological_process
85176,GO:0090675,The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.,intermicrovillar adhesion,biological_process
85177,GO:0090676,A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.,calcium ion transmembrane transport via low voltage-gated calcium channel,biological_process
85178,GO:0090677,A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.,reversible differentiation,biological_process
85179,GO:0090678,"A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.",cell dedifferentiation involved in phenotypic switching,biological_process
85180,GO:0090679,"A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.",cell differentiation involved in phenotypic switching,biological_process
85181,GO:0090680,The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane.,viral release via disruption of host outer membrane,biological_process
85182,GO:0090681,A G protein-coupled receptor activity that is responsible for the sense of taste.,GPCR taste receptor activity,molecular_function
85183,GO:0090682,A G protein-coupled receptor activity that is responsible for the sense of bitter taste.,GPCR bitter taste receptor activity,molecular_function
85184,GO:0090683,A G protein-coupled receptor activity that is responsible for the sense of sweet taste.,GPCR sweet taste receptor activity,molecular_function
85185,GO:0090684,A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.,contact chemoreceptor activity,molecular_function
85186,GO:0090685,A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.,RNA localization to nucleus,biological_process
85187,GO:0090686,Enables the transmembrane transfer of a monoatomic cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.,glycine betaine-activated nonselective monoatomic cation channel activity,molecular_function
85188,GO:0090687,Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.,activation of meiosis I spindle assembly checkpoint,biological_process
85189,GO:0090688,The part of the cleavage furrow closest to the cell surface.,cleavage furrow rim,cellular_component
85190,GO:0090689,The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.,cleavage furrow leading edge,cellular_component
85191,GO:0090691,The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.,formation of plant organ boundary,biological_process
85192,GO:0090692,The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.,mitochondrial membrane scission site,cellular_component
85193,GO:0090693,A plant organ developmental process during which a plant dismantles cellular components to reclaim the cellular building blocks and nutrients that have been deposited in the plant organs during growth.,plant organ senescence,biological_process
85194,GO:0090694,"A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.",Scc2-Scc4 cohesin loading complex,cellular_component
85195,GO:0090695,A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.,Wpl/Pds5 cohesin loading/unloading complex,cellular_component
85196,GO:0090696,"Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",post-embryonic plant organ development,biological_process
85197,GO:0090697,"Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.",post-embryonic plant organ morphogenesis,biological_process
85198,GO:0090698,"The process, occurring after plant embryonic development, by which anatomical structures are generated and organized.",post-embryonic plant morphogenesis,biological_process
85199,GO:0090700,The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,maintenance of plant organ identity,biological_process
85200,GO:0090701,The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.,specification of plant organ identity,biological_process
85201,GO:0090704,Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.,nicotinate-O-glucosyltransferase activity,molecular_function
85202,GO:0090705,A plant cell papilla that is part of a trichome cell.,trichome papilla,cellular_component
85203,GO:0090706,The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.,specification of plant organ position,biological_process
85204,GO:0090707,The process that determines the orientation of a plant organ or tissue with reference to an axis.,establishment of plant organ orientation,biological_process
85205,GO:0090708,The process in which the polarity of a plant organ axis is specified.,specification of plant organ axis polarity,biological_process
85206,GO:0090709,"Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.",regulation of timing of plant organ formation,biological_process
85207,GO:0090710,Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = ADP + CO2 + isopentenyl phosphate + phosphate.,phosphomevalonate decarboxylase activity,molecular_function
85208,GO:0090711,Catalysis of the reaction: FMN + H2O = phosphate + riboflavin.,FMN hydrolase activity,molecular_function
85209,GO:0090712,The end of the outer hair cell which receives and transmits neural signals.,basal pole of outer hair cell,cellular_component
85210,GO:0090713,Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.,immunological memory process,biological_process
85211,GO:0090714,"An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.",innate immunity memory response,biological_process
85212,GO:0090715,Any immunological memory process that can contribute to the formation of immunological memory.,immunological memory formation process,biological_process
85213,GO:0090716,"An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.",adaptive immune memory response,biological_process
85214,GO:0090717,"An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.",adaptive immune memory response involving T cells and B cells,biological_process
85215,GO:0090718,An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response.,adaptive immune effector response,biological_process
85216,GO:0090719,"An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.",adaptive immune effector response involving T cells and B lineage cells,biological_process
85217,GO:0090720,An adaptive immune response against an antigen not previously encountered by immune system.,primary adaptive immune response,biological_process
85218,GO:0090721,An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.,primary adaptive immune response involving T cells and B cells,biological_process
85219,GO:0090722,"The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function.",receptor-receptor interaction,molecular_function
85220,GO:0090724,The center of the migrating motile tip of a growing nerve cell axon or dendrite.,central region of growth cone,cellular_component
85221,GO:0090725,The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.,peripheral region of growth cone,cellular_component
85222,GO:0090726,"A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.",cortical dynamic polarity patch,cellular_component
85223,GO:0090727,Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.,positive regulation of brood size,biological_process
85224,GO:0090728,Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.,negative regulation of brood size,biological_process
85225,GO:0090729,"Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.",toxin activity,molecular_function
85226,GO:0090730,"A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).",Las1 complex,cellular_component
85227,GO:0090731,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.",cellular response to very-low-density lipoprotein particle stimulus,biological_process
85228,GO:0090732,"A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers.",cofilin-actin rod,cellular_component
85229,GO:0090733,"A homotrimeric or homohexameric extracellular matrix complex involved in cell adhesion and cell migration. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R.",tenascin complex,cellular_component
85230,GO:0090734,A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.,site of DNA damage,cellular_component
85231,GO:0090735,"The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex.",DNA repair complex assembly,biological_process
85232,GO:0090736,Binding to a meprin and TRAF homology (MATH) domain.,MATH domain binding,molecular_function
85233,GO:0090737,"A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation...",telomere maintenance via telomere trimming,biological_process
85234,GO:0090741,Any membrane that is part of a pigment granule.,pigment granule membrane,cellular_component
85235,GO:0093001,"The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.",glycolysis from storage polysaccharide through glucose-1-phosphate,biological_process
85236,GO:0093002,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.",response to nematicide,biological_process
85237,GO:0095500,The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.,acetylcholine receptor signaling pathway,biological_process
85238,GO:0097001,"Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.",ceramide binding,molecular_function
85239,GO:0097002,The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.,mitochondrial inner boundary membrane,cellular_component
85240,GO:0097003,"Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.",adipokinetic hormone receptor activity,molecular_function
85241,GO:0097004,Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.,adipokinetic hormone binding,molecular_function
85242,GO:0097005,Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.,adipokinetic hormone receptor binding,molecular_function
85243,GO:0097006,Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.,regulation of plasma lipoprotein particle levels,biological_process
85244,GO:0097007,"Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.","4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity",molecular_function
85245,GO:0097008,"Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.","(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity",molecular_function
85246,GO:0097009,Any process involved in the balance between food intake (energy input) and energy expenditure.,energy homeostasis,biological_process
85247,GO:0097010,"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.",eukaryotic translation initiation factor 4F complex assembly,biological_process
85248,GO:0097011,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.",cellular response to granulocyte macrophage colony-stimulating factor stimulus,biological_process
85249,GO:0097012,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.",response to granulocyte macrophage colony-stimulating factor,biological_process
85250,GO:0097013,The volume enclosed by the membrane of a phagocytic vesicle.,phagocytic vesicle lumen,cellular_component
85251,GO:0097014,"All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.",ciliary plasm,cellular_component
85252,GO:0097016,Binding to a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.,L27 domain binding,molecular_function
85253,GO:0097017,"A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).",renal protein absorption,biological_process
85254,GO:0097018,"A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.",renal albumin absorption,biological_process
85255,GO:0097020,"Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.",COPII receptor activity,molecular_function
85256,GO:0097021,"The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.",lymphocyte migration into lymphoid organs,biological_process
85257,GO:0097022,"The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.",lymphocyte migration into lymph node,biological_process
85258,GO:0097023,Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.,fructose 6-phosphate aldolase activity,molecular_function
85259,GO:0097025,"A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.",MPP7-DLG1-LIN7 complex,cellular_component
85260,GO:0097026,"Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.",dendritic cell dendrite assembly,biological_process
85261,GO:0097027,Binds to and increases the activity of a ubiquitin-protein transferase.,ubiquitin-protein transferase activator activity,molecular_function
85262,GO:0097028,"The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.",dendritic cell differentiation,biological_process
85263,GO:0097029,"The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.",mature conventional dendritic cell differentiation,biological_process
85264,GO:0097030,"Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).",CENP-A containing nucleosome binding,molecular_function
85265,GO:0097035,Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.,regulation of membrane lipid distribution,biological_process
85266,GO:0097036,Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.,regulation of plasma membrane sterol distribution,biological_process
85267,GO:0097037,The directed movement of heme out of a cell or organelle.,heme export,biological_process
85268,GO:0097038,"The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.",perinuclear endoplasmic reticulum,cellular_component
85269,GO:0097039,"A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.",protein linear polyubiquitination,biological_process
85270,GO:0097040,"The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.",phthiocerol biosynthetic process,biological_process
85271,GO:0097041,"The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.",phenolic phthiocerol biosynthetic process,biological_process
85272,GO:0097045,"A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.",phosphatidylserine exposure on blood platelet,biological_process
85273,GO:0097046,"Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.",replication fork progression beyond termination site,biological_process
85274,GO:0097047,A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks.,DNA replication termination region,cellular_component
85275,GO:0097048,"Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.",dendritic cell apoptotic process,biological_process
85276,GO:0097049,"Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.",motor neuron apoptotic process,biological_process
85277,GO:0097050,"Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.",type B pancreatic cell apoptotic process,biological_process
85278,GO:0097051,The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.,establishment of protein localization to endoplasmic reticulum membrane,biological_process
85279,GO:0097054,"The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.",L-glutamate biosynthetic process,biological_process
85280,GO:0097055,"The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.",agmatine biosynthetic process,biological_process
85281,GO:0097057,"A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses.",TRAF2-GSTP1 complex,cellular_component
85282,GO:0097058,A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex.,CRLF-CLCF1 complex,cellular_component
85283,GO:0097059,A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space.,CNTFR-CLCF1 complex,cellular_component
85284,GO:0097060,"A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.",synaptic membrane,cellular_component
85285,GO:0097061,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.",dendritic spine organization,biological_process
85286,GO:0097062,The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.,dendritic spine maintenance,biological_process
85287,GO:0097063,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).",cadmium ion sensor activity,molecular_function
85288,GO:0097065,"The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure.",anterior head development,biological_process
85289,GO:0097066,"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.",response to thyroid hormone,biological_process
85290,GO:0097067,"A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.",cellular response to thyroid hormone stimulus,biological_process
85291,GO:0097068,"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.",response to thyroxine,biological_process
85292,GO:0097069,"A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.",cellular response to thyroxine stimulus,biological_process
85293,GO:0097070,The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.,ductus arteriosus closure,biological_process
85294,GO:0097071,A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.,interferon regulatory factor complex,cellular_component
85295,GO:0097072,An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.,interferon regulatory factor 3 complex,cellular_component
85296,GO:0097073,An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5.,interferon regulatory factor 5 complex,cellular_component
85297,GO:0097074,An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7.,interferon regulatory factor 7 complex,cellular_component
85298,GO:0097075,An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.,interferon regulatory factor 3-interferon regulatory factor 7 complex,cellular_component
85299,GO:0097076,"A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).",transforming growth factor beta activated kinase 1 complex,cellular_component
85300,GO:0097077,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).",copper ion sensor activity,molecular_function
85301,GO:0097078,A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits.,FAL1-SGD1 complex,cellular_component
85302,GO:0097079,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in).,selenite:proton symporter activity,molecular_function
85303,GO:0097080,The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane.,plasma membrane selenite transport,biological_process
85304,GO:0097081,"The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.",vascular associated smooth muscle cell fate commitment,biological_process
85305,GO:0097082,"The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.",vascular associated smooth muscle cell fate specification,biological_process
85306,GO:0097083,"The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.",vascular associated smooth muscle cell fate determination,biological_process
85307,GO:0097084,"The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.",vascular associated smooth muscle cell development,biological_process
85308,GO:0097085,An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5.,interferon regulatory factor 3-interferon regulatory factor 5 complex,cellular_component
85309,GO:0097086,"The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone.",amniotic stem cell differentiation,biological_process
85310,GO:0097087,"The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-17A production,biological_process
85311,GO:0097088,"The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-17F production,biological_process
85312,GO:0097089,"The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.",methyl-branched fatty acid metabolic process,biological_process
85313,GO:0097090,"A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.",presynaptic membrane organization,biological_process
85314,GO:0097091,The process that results in grouping synaptic vesicles in presynaptic structures.,synaptic vesicle clustering,biological_process
85315,GO:0097093,"The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.",polyacyltrehalose biosynthetic process,biological_process
85316,GO:0097094,The process in which any suture between cranial and/or facial bones is generated and organized.,craniofacial suture morphogenesis,biological_process
85317,GO:0097095,"The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.",frontonasal suture morphogenesis,biological_process
85318,GO:0097096,The process in which any suture between facial bones is generated and organized.,facial suture morphogenesis,biological_process
85319,GO:0097097,The process in which the nasal suture is generated and organized.,nasal suture morphogenesis,biological_process
85320,GO:0097098,An activity that facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops.,DNA/RNA hybrid annealing activity,molecular_function
85321,GO:0097099,"The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo.",structural constituent of albumen,molecular_function
85322,GO:0097100,"Binding to supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.",supercoiled DNA binding,molecular_function
85323,GO:0097101,"The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.",blood vessel endothelial cell fate specification,biological_process
85324,GO:0097102,"The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.",endothelial tip cell fate specification,biological_process
85325,GO:0097103,"The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.",endothelial stalk cell fate specification,biological_process
85326,GO:0097104,"The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).",postsynaptic membrane assembly,biological_process
85327,GO:0097105,"The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.",presynaptic membrane assembly,biological_process
85328,GO:0097106,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.",postsynaptic density organization,biological_process
85329,GO:0097107,"The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.",postsynaptic density assembly,biological_process
85330,GO:0097108,"Binding to a member of the hedgehog protein family, signaling proteins involved in development.",hedgehog family protein binding,molecular_function
85331,GO:0097109,"Binding to a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.",neuroligin family protein binding,molecular_function
85332,GO:0097110,"Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.",scaffold protein binding,molecular_function
85333,GO:0097111,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.",endoplasmic reticulum-Golgi intermediate compartment organization,biological_process
85334,GO:0097112,The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.,gamma-aminobutyric acid receptor clustering,biological_process
85335,GO:0097113,The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.,AMPA glutamate receptor clustering,biological_process
85336,GO:0097114,The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.,NMDA glutamate receptor clustering,biological_process
85337,GO:0097115,The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.,neurexin clustering involved in presynaptic membrane assembly,biological_process
85338,GO:0097116,The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.,gephyrin clustering involved in postsynaptic density assembly,biological_process
85339,GO:0097117,The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.,guanylate kinase-associated protein clustering,biological_process
85340,GO:0097118,The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.,neuroligin clustering involved in postsynaptic membrane assembly,biological_process
85341,GO:0097119,"The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.",postsynaptic density protein 95 clustering,biological_process
85342,GO:0097120,"Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.",receptor localization to synapse,biological_process
85343,GO:0097121,A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin A1-CDK1 complex,cellular_component
85344,GO:0097122,A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin A2-CDK1 complex,cellular_component
85345,GO:0097123,A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin A1-CDK2 complex,cellular_component
85346,GO:0097124,A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin A2-CDK2 complex,cellular_component
85347,GO:0097125,A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin B1-CDK1 complex,cellular_component
85348,GO:0097126,A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin B2-CDK1 complex,cellular_component
85349,GO:0097127,A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin B3-CDK2 complex,cellular_component
85350,GO:0097128,A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D1-CDK4 complex,cellular_component
85351,GO:0097129,A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D2-CDK4 complex,cellular_component
85352,GO:0097130,A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D3-CDK4 complex,cellular_component
85353,GO:0097131,A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D1-CDK6 complex,cellular_component
85354,GO:0097132,A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D2-CDK6 complex,cellular_component
85355,GO:0097133,A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin D3-CDK6 complex,cellular_component
85356,GO:0097134,A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin E1-CDK2 complex,cellular_component
85357,GO:0097135,A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin E2-CDK2 complex,cellular_component
85358,GO:0097136,"A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.",Bcl-2 family protein complex,cellular_component
85359,GO:0097137,"A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.",BAD-BCL-xl complex,cellular_component
85360,GO:0097138,"A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.",BAD-BCL-2 complex,cellular_component
85361,GO:0097139,"A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.",BID-BCL-2 complex,cellular_component
85362,GO:0097140,"A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.",BIM-BCL-xl complex,cellular_component
85363,GO:0097141,"A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.",BIM-BCL-2 complex,cellular_component
85364,GO:0097142,"A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.",PUMA-BCL-2 complex,cellular_component
85365,GO:0097143,"A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.",PUMA-BCL-xl complex,cellular_component
85366,GO:0097144,"An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.",BAX complex,cellular_component
85367,GO:0097145,"An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators.",BAK complex,cellular_component
85368,GO:0097146,"A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.",NOXA-BCL-xl complex,cellular_component
85369,GO:0097147,"A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.",NOXA-BCL-2 complex,cellular_component
85370,GO:0097148,"A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.",BCL-2 complex,cellular_component
85371,GO:0097149,A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).,centralspindlin complex,cellular_component
85372,GO:0097150,Any process in by an organism or tissue maintains a population of neuronal stem cells.,neuronal stem cell population maintenance,biological_process
85373,GO:0097151,"Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.",positive regulation of inhibitory postsynaptic potential,biological_process
85374,GO:0097152,Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.,mesenchymal cell apoptotic process,biological_process
85375,GO:0097154,The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.,GABAergic neuron differentiation,biological_process
85376,GO:0097155,"The collection of sensory neuron axons into a bundle of rods, known as a fascicle.",fasciculation of sensory neuron axon,biological_process
85377,GO:0097156,"The collection of motor neuron axons into a bundle of rods, known as a fascicle.",fasciculation of motor neuron axon,biological_process
85378,GO:0097157,Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).,pre-mRNA intronic binding,molecular_function
85379,GO:0097158,Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).,pre-mRNA intronic pyrimidine-rich binding,molecular_function
85380,GO:0097160,"Binding to a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings.",polychlorinated biphenyl binding,molecular_function
85381,GO:0097161,"Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute ...",DH domain binding,molecular_function
85382,GO:0097162,"Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.",MADS box domain binding,molecular_function
85383,GO:0097163,Covalently binding to sulfur and delivering it to an acceptor molecule.,sulfur carrier activity,molecular_function
85384,GO:0097165,A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.,nuclear stress granule,cellular_component
85385,GO:0097166,"The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers...",lens epithelial cell proliferation,biological_process
85386,GO:0097167,"Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.",circadian regulation of translation,biological_process
85387,GO:0097168,"The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.",mesenchymal stem cell proliferation,biological_process
85388,GO:0097169,"An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.",AIM2 inflammasome complex,cellular_component
85389,GO:0097171,"The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.",ADP-L-glycero-beta-D-manno-heptose biosynthetic process,biological_process
85390,GO:0097172,"The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.",N-acetylmuramic acid metabolic process,biological_process
85391,GO:0097173,"The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.",N-acetylmuramic acid catabolic process,biological_process
85392,GO:0097175,"The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.","1,6-anhydro-N-acetyl-beta-muramic acid catabolic process",biological_process
85393,GO:0097176,"The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.",epoxide metabolic process,biological_process
85394,GO:0097177,Binding to a mitochondrial ribosome.,mitochondrial ribosome binding,molecular_function
85395,GO:0097178,"The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.",ruffle assembly,biological_process
85396,GO:0097179,A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.,protease inhibitor complex,cellular_component
85397,GO:0097180,A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.,serine protease inhibitor complex,cellular_component
85398,GO:0097181,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.,protein C inhibitor-coagulation factor V complex,cellular_component
85399,GO:0097182,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.,protein C inhibitor-coagulation factor Xa complex,cellular_component
85400,GO:0097183,A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.,protein C inhibitor-coagulation factor XI complex,cellular_component
85401,GO:0097184,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.",response to azide,biological_process
85402,GO:0097185,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.",cellular response to azide,biological_process
85403,GO:0097186,"The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.",amelogenesis,biological_process
85404,GO:0097187,"The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.",dentinogenesis,biological_process
85405,GO:0097188,The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.,dentin mineralization,biological_process
85406,GO:0097189,"A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.",apoptotic body,cellular_component
85407,GO:0097190,"The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.",apoptotic signaling pathway,biological_process
85408,GO:0097191,"The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.",extrinsic apoptotic signaling pathway,biological_process
85409,GO:0097192,"The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.",extrinsic apoptotic signaling pathway in absence of ligand,biological_process
85410,GO:0097193,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).",intrinsic apoptotic signaling pathway,biological_process
85411,GO:0097194,"A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed,...",execution phase of apoptosis,biological_process
85412,GO:0097195,The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.,pilomotor reflex,biological_process
85413,GO:0097196,"A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.",Shu complex,cellular_component
85414,GO:0097197,"A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.",tetraspanin-enriched microdomain,cellular_component
85415,GO:0097203,The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.,phagocytic cup lip,cellular_component
85416,GO:0097204,"The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.",phagocytic cup base,cellular_component
85417,GO:0097205,A renal system process in which fluid circulating through the body is filtered through a barrier system.,renal filtration,biological_process
85418,GO:0097206,The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.,nephrocyte filtration,biological_process
85419,GO:0097207,"A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.",bud dormancy process,biological_process
85420,GO:0097208,"A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.",alveolar lamellar body,cellular_component
85421,GO:0097209,"A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.",epidermal lamellar body,cellular_component
85422,GO:0097210,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.",response to gonadotropin-releasing hormone,biological_process
85423,GO:0097211,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.",cellular response to gonadotropin-releasing hormone,biological_process
85424,GO:0097212,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.",lysosomal membrane organization,biological_process
85425,GO:0097213,"Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.",regulation of lysosomal membrane permeability,biological_process
85426,GO:0097214,"Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.",positive regulation of lysosomal membrane permeability,biological_process
85427,GO:0097215,"Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.",negative regulation of lysosomal membrane permeability,biological_process
85428,GO:0097216,"Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.",guanosine tetraphosphate binding,molecular_function
85429,GO:0097217,A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.,sieve area,cellular_component
85430,GO:0097218,A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.,sieve plate,cellular_component
85431,GO:0097219,A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.,compound sieve plate,cellular_component
85432,GO:0097220,A sieve plate that contains a single specialized sieve area.,simple sieve plate,cellular_component
85433,GO:0097221,"A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.",M/G1 phase-specific MADS box-forkhead transcription factor complex,cellular_component
85434,GO:0097222,The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.,mitochondrial mRNA polyadenylation,biological_process
85435,GO:0097225,"The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.",sperm midpiece,cellular_component
85436,GO:0097226,The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.,sperm mitochondrial sheath,cellular_component
85437,GO:0097227,"The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.",sperm annulus,cellular_component
85438,GO:0097228,"The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near th...",sperm principal piece,cellular_component
85439,GO:0097229,"The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.",sperm end piece,cellular_component
85440,GO:0097230,Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.,cell motility in response to potassium ion,biological_process
85441,GO:0097231,Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.,cell motility in response to calcium ion,biological_process
85442,GO:0097232,"The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.",lamellar body membrane,cellular_component
85443,GO:0097233,"The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.",alveolar lamellar body membrane,cellular_component
85444,GO:0097234,"The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.",epidermal lamellar body membrane,cellular_component
85445,GO:0097237,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.",cellular response to toxic substance,biological_process
85446,GO:0097238,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.",cellular response to methylglyoxal,biological_process
85447,GO:0097240,The process in which chromatin is anchored to the nuclear envelope.,chromosome attachment to the nuclear envelope,biological_process
85448,GO:0097241,"The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.",hematopoietic stem cell migration to bone marrow,biological_process
85449,GO:0097242,The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.,amyloid-beta clearance,biological_process
85450,GO:0097243,"Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.",flavonoid binding,molecular_function
85451,GO:0097244,"Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.",flavonol binding,molecular_function
85452,GO:0097245,Binding to a flavanol.,flavanol binding,molecular_function
85453,GO:0097246,"Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.",catechin binding,molecular_function
85454,GO:0097247,"Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.",epigallocatechin 3-gallate binding,molecular_function
85455,GO:0097248,"A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.",maintenance of protein location in cell cortex of cell tip,biological_process
85456,GO:0097250,"The aggregation, arrangement and bonding together of respiratory enzyme complexes I, III and IV of the mitochondrial inner membrane to form a large supercomplex.",mitochondrial respirasome assembly,biological_process
85457,GO:0097251,"The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.",leukotriene B4 biosynthetic process,biological_process
85458,GO:0097252,"Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.",oligodendrocyte apoptotic process,biological_process
85459,GO:0097253,Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.,beta-hydroxybutyrate transmembrane transporter activity,molecular_function
85460,GO:0097254,"The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.",renal tubular secretion,biological_process
85461,GO:0097255,"A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling...",R2TP complex,cellular_component
85462,GO:0097256,Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.,phenyllactate dehydrogenase (NAD+) activity,molecular_function
85463,GO:0097257,Catalysis of the reaction: leukotriene B4 + NADP+ = 12-oxo-leukotriene B4 + NADPH + H+.,leukotriene B4 12-hydroxy dehydrogenase activity,molecular_function
85464,GO:0097258,Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase].,20-hydroxy-leukotriene B4 omega oxidase activity,molecular_function
85465,GO:0097259,Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].,20-aldehyde-leukotriene B4 20-monooxygenase activity,molecular_function
85466,GO:0097261,Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.,eoxin C4 synthase activity,molecular_function
85467,GO:0097262,Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.,eoxin D4 synthase activity,molecular_function
85468,GO:0097263,Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.,eoxin E4 synthase activity,molecular_function
85469,GO:0097264,The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.,self proteolysis,biological_process
85470,GO:0097265,"Catalysis of the reaction: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate (5-HETE) + reduced [NADPH-hemoprotein reductase] + O2 = 5,20-dihydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate (5-oxo-ETE) + oxidized [NADPH-hemoprotein reductase] + H2O + H+.",5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity,molecular_function
85471,GO:0097266,"Catalysis of the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.","phenylacetyl-CoA 1,2-epoxidase activity",molecular_function
85472,GO:0097267,The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.,omega-hydroxylase P450 pathway,biological_process
85473,GO:0097268,"A filamentous, membrane-less subcellular structure composed primarily of polymerized metabolic enzymes, most notably cytidine triphosphate synthase (CTPS). Cytoophidia are evolutionarily conserved structures found across archaea, bacteria, and eukaryotes.",cytoophidium,cellular_component
85474,GO:0097269,"Catalysis of the reaction: 7 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate.",all-trans-decaprenyl-diphosphate synthase activity,molecular_function
85475,GO:0097270,The temporary recovery of response to a stimulus when a novel stimulus is added.,dishabituation,biological_process
85476,GO:0097271,"A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.",protein localization to bud neck,biological_process
85477,GO:0097272,Any biological process involved in the maintenance of an internal steady state of ammonium.,ammonium homeostasis,biological_process
85478,GO:0097275,A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.,intracellular ammonium homeostasis,biological_process
85479,GO:0097278,Cell killing caused by the membrane attack complex formed following complement activation.,complement-dependent cytotoxicity,biological_process
85480,GO:0097279,Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.,histamine secretion mediated by IgE immunoglobulin,biological_process
85481,GO:0097280,Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.,histamine secretion mediated by immunoglobulin,biological_process
85482,GO:0097281,"The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.",immune complex formation,biological_process
85483,GO:0097282,The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.,immunoglobulin-mediated neutralization,biological_process
85484,GO:0097283,Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.,keratinocyte apoptotic process,biological_process
85485,GO:0097284,"Any apoptotic process in a hepatocyte, the main structural component of the liver.",hepatocyte apoptotic process,biological_process
85486,GO:0097288,"The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.",7-cyano-7-deazaguanine biosynthetic process,biological_process
85487,GO:0097291,"A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.",renal phosphate ion absorption,biological_process
85488,GO:0097292,"The chemical reactions and pathways involving XMP, xanthosine monophosphate.",XMP metabolic process,biological_process
85489,GO:0097293,"The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.",XMP biosynthetic process,biological_process
85490,GO:0097294,"The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.",'de novo' XMP biosynthetic process,biological_process
85491,GO:0097295,"The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.",morphine biosynthetic process,biological_process
85492,GO:0097298,Any process that modulates the size of the nucleus.,regulation of nucleus size,biological_process
85493,GO:0097300,"A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.",programmed necrotic cell death,biological_process
85494,GO:0097305,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.",response to alcohol,biological_process
85495,GO:0097306,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.",cellular response to alcohol,biological_process
85496,GO:0097307,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.",response to farnesol,biological_process
85497,GO:0097308,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.",cellular response to farnesol,biological_process
85498,GO:0097311,"A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.",bacterial biofilm matrix,cellular_component
85499,GO:0097313,"The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.",bacterial biofilm matrix surface,cellular_component
85500,GO:0097314,"The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.",apoptosome assembly,biological_process
85501,GO:0097315,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.",response to N-acetyl-D-glucosamine,biological_process
85502,GO:0097316,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.",cellular response to N-acetyl-D-glucosamine,biological_process
85503,GO:0097317,The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.,invasive growth in response to biotic stimulus,biological_process
85504,GO:0097318,The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.,invasive growth in response to abiotic stimulus,biological_process
85505,GO:0097320,A membrane tubulation process occurring in a plasma membrane.,plasma membrane tubulation,biological_process
85506,GO:0097321,The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.,"cell growth mode switching, filamentous to budding",biological_process
85507,GO:0097322,Binding to a 7SK small nuclear RNA (7SK snRNA).,7SK snRNA binding,molecular_function
85508,GO:0097323,The attachment of a B cell to another cell via adhesion molecules.,B cell adhesion,biological_process
85509,GO:0097324,"The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.",melanocyte migration,biological_process
85510,GO:0097325,"The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.",melanocyte proliferation,biological_process
85511,GO:0097326,The attachment of a melanocyte to another cell via adhesion molecules.,melanocyte adhesion,biological_process
85512,GO:0097327,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.",response to antineoplastic agent,biological_process
85513,GO:0097328,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.",response to carboplatin,biological_process
85514,GO:0097329,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.",response to antimetabolite,biological_process
85515,GO:0097330,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.",response to 5-fluoro-2'-deoxyuridine,biological_process
85516,GO:0097331,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.",response to cytarabine,biological_process
85517,GO:0097332,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.",response to antipsychotic drug,biological_process
85518,GO:0097333,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.",response to olanzapine,biological_process
85519,GO:0097334,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.",response to perphenazine,biological_process
85520,GO:0097335,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.",response to quetiapine,biological_process
85521,GO:0097336,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.",response to risperidone,biological_process
85522,GO:0097337,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.",response to ziprasidone,biological_process
85523,GO:0097338,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.",response to clozapine,biological_process
85524,GO:0097339,The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).,glycolate transmembrane transport,biological_process
85525,GO:0097341,Any process that prevents the proteolytic processing of an inactive enzyme to an active form.,zymogen inhibition,biological_process
85526,GO:0097342,"A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.",ripoptosome,cellular_component
85527,GO:0097343,"The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.",ripoptosome assembly,biological_process
85528,GO:0097345,The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.,mitochondrial outer membrane permeabilization,biological_process
85529,GO:0097346,"A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.",INO80-type complex,cellular_component
85530,GO:0097347,"A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.",TAM protein secretion complex,cellular_component
85531,GO:0097348,The lipid bilayer surrounding a host cell endocytic vesicle.,host cell endocytic vesicle membrane,cellular_component
85532,GO:0097350,The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.,neutrophil clearance,biological_process
85533,GO:0097351,Binding to a toxin to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,toxin sequestering activity,molecular_function
85534,GO:0097352,"Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.",autophagosome maturation,biological_process
85535,GO:0097353,"The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.",centrolateral pattern formation,biological_process
85536,GO:0097354,"The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.",prenylation,biological_process
85537,GO:0097355,"Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.",protein localization to heterochromatin,biological_process
85538,GO:0097356,"The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.",perinucleolar compartment,cellular_component
85539,GO:0097358,Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Removal of a D-leucine from a charged tRNA(Leu).,D-leucyl-tRNA(Leu) deacylase activity,molecular_function
85540,GO:0097359,The covalent attachment of a UDP-glucose residue to a substrate molecule.,UDP-glucosylation,biological_process
85541,GO:0097360,"The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.",chorionic trophoblast cell proliferation,biological_process
85542,GO:0097361,"A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex.",cytosolic [4Fe-4S] assembly targeting complex,cellular_component
85543,GO:0097362,A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.,MCM8-MCM9 complex,cellular_component
85544,GO:0097363,"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.",protein O-acetylglucosaminyltransferase activity,molecular_function
85545,GO:0097366,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.",response to bronchodilator,biological_process
85546,GO:0097367,Binding to a carbohydrate derivative.,carbohydrate derivative binding,molecular_function
85547,GO:0097368,"Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.",establishment of Sertoli cell barrier,biological_process
85548,GO:0097371,"Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.",MDM2/MDM4 family protein binding,molecular_function
85549,GO:0097372,"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + NAD+ + H2O = histone H3 L-lysine (position 18) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K18 to NAD, producing nicotinamide.","histone H3K18 deacetylase activity, NAD-dependent",molecular_function
85550,GO:0097373,"A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.",MCM core complex,cellular_component
85551,GO:0097374,The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.,sensory neuron axon guidance,biological_process
85552,GO:0097375,The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.,spinal sensory neuron axon guidance,biological_process
85553,GO:0097376,"The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.",interneuron axon guidance,biological_process
85554,GO:0097377,The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.,spinal cord interneuron axon guidance,biological_process
85555,GO:0097378,The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.,dorsal spinal cord interneuron axon guidance,biological_process
85556,GO:0097379,The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.,dorsal spinal cord interneuron posterior axon guidance,biological_process
85557,GO:0097380,The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.,dorsal spinal cord interneuron anterior axon guidance,biological_process
85558,GO:0097381,"Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.",photoreceptor disc membrane,cellular_component
85559,GO:0097383,Catalysis of the reaction: dIDP + H2O = dIMP + H+ + phosphate.,dIDP phosphatase activity,molecular_function
85560,GO:0097385,A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).,programmed necrotic cell death in response to starvation,biological_process
85561,GO:0097386,A prolongation or process extending from a glial cell.,glial cell projection,cellular_component
85562,GO:0097387,Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).,capitate projection,cellular_component
85563,GO:0097388,"The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 19 production,biological_process
85564,GO:0097389,"The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-C motif) ligand 21 production,biological_process
85565,GO:0097390,"The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 12 production,biological_process
85566,GO:0097391,"The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 13 production,biological_process
85567,GO:0097392,"The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",chemokine (C-X-C motif) ligand 16 production,biological_process
85568,GO:0097393,The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.,telomeric repeat-containing RNA transcription,biological_process
85569,GO:0097395,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.",response to interleukin-32,biological_process
85570,GO:0097396,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.",response to interleukin-17,biological_process
85571,GO:0097397,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.",cellular response to interleukin-32,biological_process
85572,GO:0097398,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.",cellular response to interleukin-17,biological_process
85573,GO:0097399,"The series of molecular signals initiated by interleukin-32 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-32-mediated signaling pathway,biological_process
85574,GO:0097400,"The series of molecular signals initiated by interleukin-17 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-17-mediated signaling pathway,biological_process
85575,GO:0097401,The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.,synaptic vesicle lumen acidification,biological_process
85576,GO:0097402,"The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.",neuroblast migration,biological_process
85577,GO:0097403,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.",cellular response to raffinose,biological_process
85578,GO:0097407,"Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.",Bunina body,cellular_component
85579,GO:0097408,"Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spina...",fibrillary inclusion,cellular_component
85580,GO:0097409,Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.,glial cytoplasmic inclusion,cellular_component
85581,GO:0097410,The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.,hippocampal interneuron differentiation,biological_process
85582,GO:0097411,"The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.",hypoxia-inducible factor-1alpha signaling pathway,biological_process
85583,GO:0097412,"A glass-like, pale intracellular inclusion.",hyaline inclusion,cellular_component
85584,GO:0097413,"Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.",Lewy body,cellular_component
85585,GO:0097414,"Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.",classical Lewy body,cellular_component
85586,GO:0097415,Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.,cortical Lewy body,cellular_component
85587,GO:0097416,"Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.",Lewy body-like hyaline inclusion,cellular_component
85588,GO:0097417,"Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cel...",nematosome,cellular_component
85589,GO:0097418,"Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.",neurofibrillary tangle,cellular_component
85590,GO:0097419,"Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.",Pick body,cellular_component
85591,GO:0097420,Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.,skein-like inclusion,cellular_component
85592,GO:0097421,The regrowth of lost or destroyed liver.,liver regeneration,biological_process
85593,GO:0097422,A network of fine tubules in the vicinity of the Golgi complex and around the centriole.,tubular endosome,cellular_component
85594,GO:0097423,An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associ...,mitochondrion-associated adherens complex,cellular_component
85595,GO:0097424,"Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.",nucleolus-associated heterochromatin,cellular_component
85596,GO:0097426,An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.,glial filament,cellular_component
85597,GO:0097427,An arrangement of closely apposed microtubules running parallel to each other.,microtubule bundle,cellular_component
85598,GO:0097429,"Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.",amino acid ligation activity by nonribosomal peptide synthase,molecular_function
85599,GO:0097430,"The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol.",copper ion import across prospore membrane,biological_process
85600,GO:0097431,"Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.",mitotic spindle pole,cellular_component
85601,GO:0097432,"The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.",hippocampal pyramidal neuron differentiation,biological_process
85602,GO:0097433,An electron dense body which may contain granules.,dense body,cellular_component
85603,GO:0097434,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).,succinate:proton symporter activity,molecular_function
85604,GO:0097435,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.",supramolecular fiber organization,biological_process
85605,GO:0097436,The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.,entry into dormancy,biological_process
85606,GO:0097437,The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.,maintenance of dormancy,biological_process
85607,GO:0097438,The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.,exit from dormancy,biological_process
85608,GO:0097439,"The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.",acquisition of desiccation tolerance,biological_process
85609,GO:0097440,"A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.",apical dendrite,cellular_component
85610,GO:0097441,"A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.",basal dendrite,cellular_component
85611,GO:0097442,A dendrite of a hippocampal CA3 pyramidal cell.,CA3 pyramidal cell dendrite,cellular_component
85612,GO:0097443,A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.,sorting endosome,cellular_component
85613,GO:0097444,A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum.,spine apparatus,cellular_component
85614,GO:0097445,Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.,presynaptic active zone dense projection,cellular_component
85615,GO:0097446,"A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.",protein localization to eisosome filament,biological_process
85616,GO:0097447,"The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.",dendritic tree,cellular_component
85617,GO:0097448,A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.,spine mat,cellular_component
85618,GO:0097449,A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.,astrocyte projection,cellular_component
85619,GO:0097450,Terminal process of astrocyte abutting non-neuronal surfaces in the brain.,astrocyte end-foot,cellular_component
85620,GO:0097451,"Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.",glial limiting end-foot,cellular_component
85621,GO:0097452,"A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.",GAIT complex,cellular_component
85622,GO:0097453,"Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.",mesaxon,cellular_component
85623,GO:0097454,Small finger-like extension of a Schwann cell that contacts the nodal membrane.,Schwann cell microvillus,cellular_component
85624,GO:0097455,Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.,spiny bracelet of Nageotte,cellular_component
85625,GO:0097456,Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.,terminal loop,cellular_component
85626,GO:0097457,"An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.",hippocampal mossy fiber,cellular_component
85627,GO:0097462,"Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.",Lewy neurite,cellular_component
85628,GO:0097463,"Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.",gemmule,cellular_component
85629,GO:0097464,Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.,thorny excrescence,cellular_component
85630,GO:0097465,Spine emanating from the cell soma of a neuron.,somatic spine,cellular_component
85631,GO:0097466,"An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.",ubiquitin-dependent glycoprotein ERAD pathway,biological_process
85632,GO:0097467,"Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.",type III terminal bouton,cellular_component
85633,GO:0097468,"Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.",programmed cell death in response to reactive oxygen species,biological_process
85634,GO:0097470,"Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.",ribbon synapse,cellular_component
85635,GO:0097471,A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.,mossy fiber rosette,cellular_component
85636,GO:0097472,"Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.",cyclin-dependent protein kinase activity,molecular_function
85637,GO:0097473,"Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.",retinal rod cell apoptotic process,biological_process
85638,GO:0097474,"Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.",retinal cone cell apoptotic process,biological_process
85639,GO:0097475,The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.,motor neuron migration,biological_process
85640,GO:0097476,The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.,spinal cord motor neuron migration,biological_process
85641,GO:0097477,The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.,lateral motor column neuron migration,biological_process
85642,GO:0097478,Any of the two layers of lipid molecules that constitute a membrane.,leaflet of membrane bilayer,cellular_component
85643,GO:0097479,"Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location.",synaptic vesicle localization,biological_process
85644,GO:0097480,The directed movement of a synaptic vesicle or vesicles to a specific location.,establishment of synaptic vesicle localization,biological_process
85645,GO:0097482,A postsynaptic specialization that is part of a neuromuscular junction.,muscle cell postsynaptic specialization,cellular_component
85646,GO:0097484,Long distance growth of a single dendrite involved in cellular development.,dendrite extension,biological_process
85647,GO:0097485,The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.,neuron projection guidance,biological_process
85648,GO:0097486,The volume enclosed by the outermost membrane of a multivesicular body.,multivesicular body lumen,cellular_component
85649,GO:0097487,A membrane-bounded vesicle wholly contained within a multivesicular body.,"multivesicular body, internal vesicle",cellular_component
85650,GO:0097488,The lipid bilayer surrounding a multivesicular body internal vesicle.,"multivesicular body, internal vesicle membrane",cellular_component
85651,GO:0097489,The volume enclosed by the membrane of the multivesicular body internal vesicle.,"multivesicular body, internal vesicle lumen",cellular_component
85652,GO:0097490,"Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.",sympathetic neuron projection extension,biological_process
85653,GO:0097491,The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.,sympathetic neuron projection guidance,biological_process
85654,GO:0097492,The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.,sympathetic neuron axon guidance,biological_process
85655,GO:0097493,"The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.",structural molecule activity conferring elasticity,molecular_function
85656,GO:0097494,Any process that modulates the size of a vesicle.,regulation of vesicle size,biological_process
85657,GO:0097495,"A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.",H-NS-Hha complex,cellular_component
85658,GO:0097496,"A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.",blood vessel lumen ensheathment,biological_process
85659,GO:0097497,The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.,blood vessel endothelial cell delamination,biological_process
85660,GO:0097498,Any endothelial tube morphogenesis process by which the tube is increased in length.,endothelial tube lumen extension,biological_process
85661,GO:0097499,"A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.",protein localization to non-motile cilium,biological_process
85662,GO:0097500,"A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium.",receptor localization to non-motile cilium,biological_process
85663,GO:0097501,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.",stress response to metal ion,biological_process
85664,GO:0097503,The covalent attachment of sialic acid to a substrate molecule.,sialylation,biological_process
85665,GO:0097504,"Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology...",Gemini of Cajal bodies,cellular_component
85666,GO:0097505,"A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.",Rad6-Rad18 complex,cellular_component
85667,GO:0097506,DNA N-glycosylase activity acting on deaminated bases.,deaminated base DNA N-glycosylase activity,molecular_function
85668,GO:0097507,DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).,hypoxanthine DNA N-glycosylase activity,molecular_function
85669,GO:0097508,DNA N-glycosylase activity acting on deaminated guanine (xanthine).,xanthine DNA N-glycosylase activity,molecular_function
85670,GO:0097509,DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.,oxanine DNA N-glycosylase activity,molecular_function
85671,GO:0097510,"A base-excision repair, AP site formation process occurring via excision of a deaminated base.","base-excision repair, AP site formation via deaminated base removal",biological_process
85672,GO:0097511,"A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.",dendritic cell dendrite,cellular_component
85673,GO:0097512,A cardiac myofibril is a myofibril specific to cardiac muscle cells.,cardiac myofibril,cellular_component
85674,GO:0097513,A bipolar filament composed of myosin II molecules.,myosin II filament,cellular_component
85675,GO:0097514,A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.,sexual spore wall,cellular_component
85676,GO:0097515,A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.,asexual spore wall,cellular_component
85677,GO:0097516,A parallel bundle of actin filaments at the core of a microvillus.,microvillar actin bundle,cellular_component
85678,GO:0097517,An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.,contractile actin filament bundle,cellular_component
85679,GO:0097518,An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.,parallel actin filament bundle,cellular_component
85680,GO:0097519,A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.,DNA recombinase complex,cellular_component
85681,GO:0097520,"A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage.","nucleotide-excision repair, preincision complex",cellular_component
85682,GO:0097522,A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.,protein-DNA ISRE complex,cellular_component
85683,GO:0097523,"A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript.",transcription ternary complex,cellular_component
85684,GO:0097524,A plasma membrane that is part of a sperm cell.,sperm plasma membrane,cellular_component
85685,GO:0097525,A small ribonucleoprotein complex involved in formation of the spliceosome.,spliceosomal snRNP complex,cellular_component
85686,GO:0097526,A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP.,spliceosomal tri-snRNP complex,cellular_component
85687,GO:0097527,"The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.",necroptotic signaling pathway,biological_process
85688,GO:0097528,"A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The...",execution phase of necroptosis,biological_process
85689,GO:0097529,The movement of a myeloid leukocyte within or between different tissues and organs of the body.,myeloid leukocyte migration,biological_process
85690,GO:0097530,The movement of a granulocyte within or between different tissues and organs of the body.,granulocyte migration,biological_process
85691,GO:0097531,The movement of a mast cell within or between different tissues and organs of the body.,mast cell migration,biological_process
85692,GO:0097532,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.",stress response to acid chemical,biological_process
85693,GO:0097533,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.",cellular stress response to acid chemical,biological_process
85694,GO:0097534,"The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.",lymphoid lineage cell migration,biological_process
85695,GO:0097535,The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.,lymphoid lineage cell migration into thymus,biological_process
85696,GO:0097536,The process in which the thymus epithelium is generated and organized.,thymus epithelium morphogenesis,biological_process
85697,GO:0097537,"A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium.",Y-shaped link,cellular_component
85698,GO:0097538,A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links.,ciliary necklace,cellular_component
85699,GO:0097539,"A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).",ciliary transition fiber,cellular_component
85700,GO:0097540,Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.,axonemal central pair,cellular_component
85701,GO:0097541,Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure.,axonemal basal plate,cellular_component
85702,GO:0097542,"Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.",ciliary tip,cellular_component
85703,GO:0097543,"Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.",ciliary inversin compartment,cellular_component
85704,GO:0097544,The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.,ciliary shaft,cellular_component
85705,GO:0097545,A cellular anatomical entity that is part of an axoneme consisting of a doublet microtubule.,axonemal doublet microtubule,cellular_component
85706,GO:0097546,"Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.",ciliary base,cellular_component
85707,GO:0097547,"A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.",synaptic vesicle protein transport vesicle,cellular_component
85708,GO:0097548,The controlled shedding of a seed.,seed abscission,biological_process
85709,GO:0097550,"A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.",transcription preinitiation complex,cellular_component
85710,GO:0097551,The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.,mitochondrial double-strand break repair,biological_process
85711,GO:0097552,The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.,mitochondrial double-strand break repair via homologous recombination,biological_process
85712,GO:0097553,A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.,calcium ion transmembrane import into cytosol,biological_process
85713,GO:0097554,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.",left anterior flagellum,cellular_component
85714,GO:0097555,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.",right anterior flagellum,cellular_component
85715,GO:0097556,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.",left posteriolateral flagellum,cellular_component
85716,GO:0097557,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.",right posteriolateral flagellum,cellular_component
85717,GO:0097558,A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.,left ventral flagellum,cellular_component
85718,GO:0097559,A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.,right ventral flagellum,cellular_component
85719,GO:0097560,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.",left caudal flagellum,cellular_component
85720,GO:0097561,"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.",right caudal flagellum,cellular_component
85721,GO:0097562,Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.,left lateral basal body pair,cellular_component
85722,GO:0097563,Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.,left middle basal body pair,cellular_component
85723,GO:0097564,Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.,right lateral basal body pair,cellular_component
85724,GO:0097565,Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.,right middle basal body pair,cellular_component
85725,GO:0097566,"Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).",left tetrad,cellular_component
85726,GO:0097567,"Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).",right tetrad,cellular_component
85727,GO:0097568,"A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.",median body,cellular_component
85728,GO:0097569,"Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.",lateral shield,cellular_component
85729,GO:0097570,"The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.",cyst wall,cellular_component
85730,GO:0097571,One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.,left nucleus,cellular_component
85731,GO:0097572,One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.,right nucleus,cellular_component
85732,GO:0097574,"The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.",lateral part of cell,cellular_component
85733,GO:0097575,The region directly beneath the plasma membrane of the lateral portion of the cell.,lateral cell cortex,cellular_component
85734,GO:0097576,"Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.",vacuole fusion,biological_process
85735,GO:0097581,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.",lamellipodium organization,biological_process
85736,GO:0097582,"A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.",dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex,cellular_component
85737,GO:0097583,"A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.",dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex,cellular_component
85738,GO:0097584,"A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.",dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex,cellular_component
85739,GO:0097585,"A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.",dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex,cellular_component
85740,GO:0097586,"A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.",dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex,cellular_component
85741,GO:0097587,"A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.",MutLgamma complex,cellular_component
85742,GO:0097588,Cell motility due to movement of bacterial- or archaeal-type flagella.,archaeal or bacterial-type flagellum-dependent cell motility,biological_process
85743,GO:0097589,"A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modif...",archaeal-type flagellum,cellular_component
85744,GO:0097590,"Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.",archaeal-type flagellum-dependent cell motility,biological_process
85745,GO:0097591,Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.,ventral disc lateral crest,cellular_component
85746,GO:0097592,A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).,ventral disc overlap zone,cellular_component
85747,GO:0097593,A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.,ventral disc microtubule array,cellular_component
85748,GO:0097594,Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons.,ventral disc dorsal microribbon,cellular_component
85749,GO:0097595,Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet.,ventral disc crossbridge,cellular_component
85750,GO:0097596,A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage).,ventral disc supernumerary microtubule array,cellular_component
85751,GO:0097597,"Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved ...",ventral disc,cellular_component
85752,GO:0097598,"A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytopl...",sperm cytoplasmic droplet,cellular_component
85753,GO:0097599,"Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues.",xylanase activity,molecular_function
85754,GO:0097600,A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.,exoxylanase activity,molecular_function
85755,GO:0097601,A retina homeostatic process preventing the degeneration of a retina blood vessel.,retina blood vessel maintenance,biological_process
85756,GO:0097602,"Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).",cullin family protein binding,molecular_function
85757,GO:0097603,Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).,temperature-gated ion channel activity,molecular_function
85758,GO:0097604,Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).,temperature-gated cation channel activity,molecular_function
85759,GO:0097608,"A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum.",transverse flagellum,cellular_component
85760,GO:0097609,"A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.",longitudinal flagellum,cellular_component
85761,GO:0097610,A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates.,cell surface furrow,cellular_component
85762,GO:0097611,A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it.,dinoflagellate cingulum,cellular_component
85763,GO:0097612,A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell.,dinoflagellate sulcus,cellular_component
85764,GO:0097613,The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum.,dinoflagellate epicone,cellular_component
85765,GO:0097614,The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum.,dinoflagellate hypocone,cellular_component
85766,GO:0097618,A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed.,dinoflagellate sulcal notch,cellular_component
85767,GO:0097619,"A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EX...",PTEX complex,cellular_component
85768,GO:0097620,Catalysis of the reaction: (R)-mandelate + NAD+ = phenylglyoxylate + NADH + H+.,(R)-mandelate dehydrogenase activity,molecular_function
85769,GO:0097621,Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.,monoamine oxidase activity,molecular_function
85770,GO:0097622,"The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.",cytoplasmic translational elongation through polyproline stretches,biological_process
85771,GO:0097623,"The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.",potassium ion export across plasma membrane,biological_process
85772,GO:0097624,The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane.,UDP-galactose transmembrane import into Golgi lumen,biological_process
85773,GO:0097625,Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity basic amino acid transmembrane transporter activity,molecular_function
85774,GO:0097626,Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.,low-affinity L-arginine transmembrane transporter activity,molecular_function
85775,GO:0097627,Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity L-ornithine transmembrane transporter activity,molecular_function
85776,GO:0097628,The orderly movement of a distal tip cell.,distal tip cell migration,biological_process
85777,GO:0097629,"The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of omegasome membrane,cellular_component
85778,GO:0097632,"The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of phagophore assembly site membrane,cellular_component
85779,GO:0097638,"The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.",L-arginine import across plasma membrane,biological_process
85780,GO:0097639,"The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.",L-lysine import across plasma membrane,biological_process
85781,GO:0097640,"The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.",L-ornithine import across plasma membrane,biological_process
85782,GO:0097641,Catalysis of the reaction: xanthine + 2-oxoglutarate + O2 = urate + succinate + CO2.,alpha-ketoglutarate-dependent xanthine dioxygenase activity,molecular_function
85783,GO:0097642,"Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.",calcitonin family receptor activity,molecular_function
85784,GO:0097643,Combining with amylin to initiate a change in cell activity.,amylin receptor activity,molecular_function
85785,GO:0097644,"Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).",calcitonin family binding,molecular_function
85786,GO:0097645,Binding to amylin.,amylin binding,molecular_function
85787,GO:0097646,"A G protein-coupled receptor signaling pathway initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",calcitonin family receptor signaling pathway,biological_process
85788,GO:0097647,"A G protein-coupled receptor signaling pathway initiated by amylin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",amylin receptor signaling pathway,biological_process
85789,GO:0097648,A protein complex that contains G protein-coupled receptors.,G protein-coupled receptor complex,cellular_component
85790,GO:0097649,"A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.",A axonemal microtubule,cellular_component
85791,GO:0097650,An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.,B axonemal microtubule,cellular_component
85792,GO:0097651,"A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vert...","phosphatidylinositol 3-kinase complex, class I",cellular_component
85793,GO:0097652,"A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.","phosphatidylinositol 3-kinase complex, class II",cellular_component
85794,GO:0097653,The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.,unencapsulated part of cell,cellular_component
85795,GO:0097654,"A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.",platelet SNARE complex,cellular_component
85796,GO:0097655,"Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory func...",serpin family protein binding,molecular_function
85797,GO:0097656,"A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.",cell-cell self recognition,biological_process
85798,GO:0097657,"Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.","3',5'-nucleotide bisphosphate phosphatase activity",molecular_function
85799,GO:0097658,"A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.",Asi complex,cellular_component
85800,GO:0097660,An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.,SCF-Cdc4 ubiquitin ligase complex,cellular_component
85801,GO:0097661,An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.,SCF-Ctf13 ubiquitin ligase complex,cellular_component
85802,GO:0097662,An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.,SCF-Das1 ubiquitin ligase complex,cellular_component
85803,GO:0097663,An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).,SCF-Dia2/Pof3 ubiquitin ligase complex,cellular_component
85804,GO:0097664,An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).,SCF-Grr1/Pof2 ubiquitin ligase complex,cellular_component
85805,GO:0097665,An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.,SCF-Mdm30 ubiquitin ligase complex,cellular_component
85806,GO:0097666,An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).,SCF-Met30/Pof1 ubiquitin ligase complex,cellular_component
85807,GO:0097667,An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).,SCF-Rcy1/Pof6 ubiquitin ligase complex,cellular_component
85808,GO:0097668,An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).,SCF-Saf1/Pof9 ubiquitin ligase complex,cellular_component
85809,GO:0097669,An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.,SCF-Skp2 ubiquitin ligase complex,cellular_component
85810,GO:0097670,An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).,SCF-Ufo1/Pof10 ubiquitin ligase complex,cellular_component
85811,GO:0097671,An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.,SCF-YDR131C ubiquitin ligase complex,cellular_component
85812,GO:0097672,An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).,SCF-Pof5 ubiquitin ligase complex,cellular_component
85813,GO:0097673,An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.,SCF-Ucc1 ubiquitin ligase complex,cellular_component
85814,GO:0097674,An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.,SCF-YLR352W ubiquitin ligase complex,cellular_component
85815,GO:0097675,An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).,SCF-Hrt3/Pof7 ubiquitin ligase complex,cellular_component
85816,GO:0097677,"Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.",STAT family protein binding,molecular_function
85817,GO:0097678,"Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.",SOCS family protein binding,molecular_function
85818,GO:0097680,"An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).",double-strand break repair via classical nonhomologous end joining,biological_process
85819,GO:0097681,"An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.",double-strand break repair via alternative nonhomologous end joining,biological_process
85820,GO:0097682,"Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.","intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity",molecular_function
85821,GO:0097683,The anterior most point of a dinoflagellate epicone.,dinoflagellate apex,cellular_component
85822,GO:0097684,The anterior most point of a dinoflagellate hypocone.,dinoflagellate antapex,cellular_component
85823,GO:0097685,A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.,dinoflagellate apical groove,cellular_component
85824,GO:0097686,A horn-shaped dinoflagellate apex found in thecate species.,dinoflagellate apical horn,cellular_component
85825,GO:0097687,A horn-shaped dinoflagellate antapex found in thecate species.,dinoflagellate antapical horn,cellular_component
85826,GO:0097688,The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.,glutamate receptor clustering,biological_process
85827,GO:0097690,"Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.",iron ion transmembrane transporter inhibitor activity,molecular_function
85828,GO:0097691,"Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.",bacterial extracellular vesicle,cellular_component
85829,GO:0097693,"Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.",ocelloid,cellular_component
85830,GO:0097694,The directed movement of RNA to a specific location in the telomeric region of a chromosome.,establishment of RNA localization to telomere,biological_process
85831,GO:0097695,The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.,establishment of protein-containing complex localization to telomere,biological_process
85832,GO:0097696,"An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.",cell surface receptor signaling pathway via STAT,biological_process
85833,GO:0097697,Catalysis of the reaction: 5-carboxymethoxyuridine34 in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine34 in tRNA + S-adenosyl-L-homocysteine. The methylation occurs on the modified base.,tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity,molecular_function
85834,GO:0097698,"A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.",telomere maintenance via base-excision repair,biological_process
85835,GO:0097699,Any response to fluid shear stress in a vascular endothelial cell.,vascular endothelial cell response to fluid shear stress,biological_process
85836,GO:0097700,Any response to laminar fluid shear stress in a vascular endothelial cell.,vascular endothelial cell response to laminar fluid shear stress,biological_process
85837,GO:0097701,"Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.",response to pulsatile fluid shear stress,biological_process
85838,GO:0097702,"Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.",response to oscillatory fluid shear stress,biological_process
85839,GO:0097703,Any response to pulsatile fluid shear stress that occurs at the level of a cell.,cellular response to pulsatile fluid shear stress,biological_process
85840,GO:0097704,Any response to oscillatory fluid shear stress that occurs at the level of a cell.,cellular response to oscillatory fluid shear stress,biological_process
85841,GO:0097705,Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.,vascular endothelial cell response to pulsatile fluid shear stress,biological_process
85842,GO:0097706,Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.,vascular endothelial cell response to oscillatory fluid shear stress,biological_process
85843,GO:0097707,"A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process i...",ferroptosis,biological_process
85844,GO:0097708,Any vesicle that is part of the intracellular region.,intracellular vesicle,cellular_component
85845,GO:0097709,"The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.",connective tissue replacement,biological_process
85846,GO:0097710,The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.,"viral terminase, small subunit",cellular_component
85847,GO:0097712,"The directed movement of substances from the trans-Golgi network to the periciliary membrane compartment, the specialized region of the plasma membrane surrounding the base of the cilium including the ciliary pocket, via vesicle-mediated transport.",trans-Golgi to periciliary membrane compartment transport,biological_process
85848,GO:0097713,Binds to and modulates the activity of dolichol-phosphate-mannose synthase.,dolichol-phosphate-mannose synthase regulator activity,molecular_function
85849,GO:0097714,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.",response to viscosity,biological_process
85850,GO:0097715,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.",cellular response to viscosity,biological_process
85851,GO:0097716,The directed movement of copper (Cu) ions passing through the blood-brain barrier.,copper ion transport across blood-brain barrier,biological_process
85852,GO:0097717,The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.,copper ion transport across blood-cerebrospinal fluid barrier,biological_process
85853,GO:0097718,Binding to a disordered domain of a protein.,disordered domain specific binding,molecular_function
85854,GO:0097719,The regrowth of neural tissue following its loss or destruction.,neural tissue regeneration,biological_process
85855,GO:0097720,"Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signali...",calcineurin-mediated signaling,biological_process
85856,GO:0097721,"A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.",ciliary vesicle,cellular_component
85857,GO:0097722,Any process involved in the controlled movement of a sperm cell.,sperm motility,biological_process
85858,GO:0097723,Any process involved in the controlled movement of an amoeboid sperm cell.,amoeboid sperm motility,biological_process
85859,GO:0097726,"Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).",LEM domain binding,molecular_function
85860,GO:0097727,"An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.",blepharoplast,cellular_component
85861,GO:0097728,A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).,9+0 motile cilium,cellular_component
85862,GO:0097729,A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).,9+2 motile cilium,cellular_component
85863,GO:0097730,A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.,non-motile cilium,cellular_component
85864,GO:0097731,A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).,9+0 non-motile cilium,cellular_component
85865,GO:0097732,A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).,9+2 non-motile cilium,cellular_component
85866,GO:0097733,A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.,photoreceptor cell cilium,cellular_component
85867,GO:0097734,"The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.",extracellular exosome biogenesis,biological_process
85868,GO:0097735,"A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.",DIM/DIP cell wall layer,cellular_component
85869,GO:0097736,"The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.",aerial mycelium formation,biological_process
85870,GO:0097737,"A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.",acquisition of mycelium reproductive competence,biological_process
85871,GO:0097738,"The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.",substrate mycelium formation,biological_process
85872,GO:0097739,"Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.",negative regulation of ferrichrome biosynthetic process in response to iron,biological_process
85873,GO:0097740,"A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signaling and metabolism, and in calcium signaling.",paraflagellar rod,cellular_component
85874,GO:0097741,"A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.",mastigoneme,cellular_component
85875,GO:0097742,"Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.",de novo centriole assembly,biological_process
85876,GO:0097743,"A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.",de novo centriole assembly via blepharoplast,biological_process
85877,GO:0097744,The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.,renal urate salt excretion,biological_process
85878,GO:0097745,The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.,mitochondrial tRNA 5'-end processing,biological_process
85879,GO:0097746,Any process that modulates the diameter of blood vessels.,blood vessel diameter maintenance,biological_process
85880,GO:0097747,Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.,RNA polymerase activity,molecular_function
85881,GO:0097748,"Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.",3'-5' RNA polymerase activity,molecular_function
85882,GO:0097749,A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).,membrane tubulation,biological_process
85883,GO:0097750,A membrane tubulation process occurring in an endosome membrane.,endosome membrane tubulation,biological_process
85884,GO:0097751,The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.,spore-bearing structure formation,biological_process
85885,GO:0097752,Any process that modulates the stability of DNA.,regulation of DNA stability,biological_process
85886,GO:0097753,A membrane organization process resulting in the bending of a membrane.,membrane bending,biological_process
85887,GO:0097754,A membrane bending process mediated by clathrin.,clathrin-mediated membrane bending,biological_process
85888,GO:0098001,"Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.",receptor-mediated bacteriophage reversible attachment to host cell,biological_process
85889,GO:0098002,The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.,receptor-mediated bacteriophage irreversible attachment to host cell,biological_process
85890,GO:0098003,"The aggregation, arrangement and bonding together of a set of components to form a virus tail.",viral tail assembly,biological_process
85891,GO:0098004,"The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.",virus tail fiber assembly,biological_process
85892,GO:0098005,Process by which virus heads and tails are attached to each other.,viral head-tail joining,biological_process
85893,GO:0098006,The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.,"viral DNA genome packaging, headful",biological_process
85894,GO:0098009,The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.,"viral terminase, large subunit",cellular_component
85895,GO:0098015,"Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.",virus tail,cellular_component
85896,GO:0098017,"The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.","viral capsid, major subunit",cellular_component
85897,GO:0098018,"The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.","viral capsid, minor subunit",cellular_component
85898,GO:0098021,"Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential.","viral capsid, decoration",cellular_component
85899,GO:0098022,A type of capsid decoration composed of fiber structures.,"viral capsid, fiber",cellular_component
85900,GO:0098023,"The basal end of the virus tail, which is used by the virus to attach to the host cell.","virus tail, tip",cellular_component
85901,GO:0098024,"The fibrous region of the virus tail used to scan, recognize and attach to the host cell.","virus tail, fiber",cellular_component
85902,GO:0098025,Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.,"virus tail, baseplate",cellular_component
85903,GO:0098026,The internal tube of the tail of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.,"virus tail, tube",cellular_component
85904,GO:0098027,The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.,"virus tail, sheath",cellular_component
85905,GO:0098028,The tube of the non-contractile tails of some viruses.,"virus tail, shaft",cellular_component
85906,GO:0098029,"A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.","icosahedral viral capsid, spike",cellular_component
85907,GO:0098030,A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).,"icosahedral viral capsid, neck",cellular_component
85908,GO:0098031,A small disk located at the base of some icosahedral virus capsids.,"icosahedral viral capsid, collar",cellular_component
85909,GO:0098032,A fiber attached to the collar structure of some icosahedral viral capsids.,"icosahedral viral capsid, collar fiber",cellular_component
85910,GO:0098033,A fiber attached to the neck at the base of some icosahedral viral capsids.,"icosahedral viral capsid, neck fiber",cellular_component
85911,GO:0098035,"The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.",viral DNA genome packaging via site-specific sequence recognition,biological_process
85912,GO:0098036,"The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.","viral DNA genome packaging, 3' extended cos packaging",biological_process
85913,GO:0098037,"The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.","viral DNA genome packaging, 5' extended cos packaging",biological_process
85914,GO:0098038,Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.,non-replicative DNA transposition,biological_process
85915,GO:0098039,Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.,replicative DNA transposition,biological_process
85916,GO:0098045,"The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.",virus baseplate assembly,biological_process
85917,GO:0098046,"A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).",type V protein secretion system complex,cellular_component
85918,GO:0098061,"The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.","viral capsid, internal space",cellular_component
85919,GO:0098505,"Binding to G-rich, single-stranded, telomere-associated DNA.",G-rich strand telomeric DNA binding,molecular_function
85920,GO:0098506,The process of removing one or more phosphate groups from the 3' end of a polynucleotide.,polynucleotide 3' dephosphorylation,biological_process
85921,GO:0098507,The process of removing one or more phosphate groups from the 5' end of a polynucleotide.,polynucleotide 5' dephosphorylation,biological_process
85922,GO:0098508,The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.,endothelial to hematopoietic transition,biological_process
85923,GO:0098509,"The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of humidity,biological_process
85924,GO:0098510,"The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of high humidity,biological_process
85925,GO:0098511,"The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.",sensory perception of low humidity,biological_process
85926,GO:0098512,The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.,detection of humidity stimulus involved in sensory perception,biological_process
85927,GO:0098513,The series of events in which a humidity stimulus is received and converted into a molecular signal.,detection of humidity,biological_process
85928,GO:0098516,The series of events in which high humidity is detected and converted into a molecular signal.,detection of high humidity,biological_process
85929,GO:0098517,The series of events in which low humidity is detected and converted into a molecular signal.,detection of low humidity,biological_process
85930,GO:0098520,"The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.",excitatory neuromuscular junction,cellular_component
85931,GO:0098521,"The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.",inhibitory neuromuscular junction,cellular_component
85932,GO:0098522,A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.,neuromuscular junction of skeletal muscle fiber,cellular_component
85933,GO:0098523,A neuromuscular junction in which the target muscle cell is a myotube.,neuromuscular junction of myotube,cellular_component
85934,GO:0098524,"A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.",neuromuscular junction of somatic muscle myotube,cellular_component
85935,GO:0098525,"A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.",excitatory neuromuscular junction of somatic myotube,cellular_component
85936,GO:0098526,A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.,inhibitory neuromuscular junction of somatic myotube,cellular_component
85937,GO:0098527,"A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.",neuromuscular junction of somatic muscle,cellular_component
85938,GO:0098528,The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.,skeletal muscle fiber differentiation,biological_process
85939,GO:0098529,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.","neuromuscular junction development, skeletal muscle fiber",biological_process
85940,GO:0098530,"Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.",positive regulation of strand invasion,biological_process
85941,GO:0098531,A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific genes and gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.,ligand-modulated transcription factor activity,molecular_function
85942,GO:0098533,A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.,ATPase dependent transmembrane transport complex,cellular_component
85943,GO:0098534,A cellular process that results in the assembly of one or more centrioles.,centriole assembly,biological_process
85944,GO:0098535,"Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.",de novo centriole assembly involved in multi-ciliated epithelial cell differentiation,biological_process
85945,GO:0098536,"A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.",deuterosome,cellular_component
85946,GO:0098538,"The leaflet of a transport vesicle membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of transport vesicle membrane,cellular_component
85947,GO:0098539,"The leaflet of the transport vesicle membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of transport vesicle membrane,cellular_component
85948,GO:0098540,"The leaflet of a trans-Golgi network transport vesicle membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of trans-Golgi network transport vesicle membrane,cellular_component
85949,GO:0098541,"The leaflet of the trans-Golgi network transport vesicle membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of trans-Golgi network transport vesicle membrane,cellular_component
85950,GO:0098542,Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.,defense response to other organism,biological_process
85951,GO:0098543,The series of events in which a stimulus from another organism is received and converted into a molecular signal.,detection of other organism,biological_process
85952,GO:0098544,"Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.",maintenance of protein complex location,biological_process
85953,GO:0098545,Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.,maintenance of protein complex location in cytoplasm,biological_process
85954,GO:0098547,"The leaflet of the Golgi membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of Golgi membrane,cellular_component
85955,GO:0098548,"The leaflet of the Golgi membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of Golgi membrane,cellular_component
85956,GO:0098549,A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.,somatic ring canal,cellular_component
85957,GO:0098550,"The leaflet of the early endosome membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of early endosome membrane,cellular_component
85958,GO:0098551,"The leaflet of the late endosomal membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of late endosome membrane,cellular_component
85959,GO:0098552,A cellular component consisting of one leaflet of a membrane bilayer and any protein embedded or anchored in it or attached to its surface.,side of membrane,cellular_component
85960,GO:0098553,"The leaflet of the endoplasmic reticulum membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of endoplasmic reticulum membrane,cellular_component
85961,GO:0098554,"The leaflet of the endoplasmic reticulum membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of endoplasmic reticulum membrane,cellular_component
85962,GO:0098555,"The leaflet of the rough endoplasmic reticulum membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of rough endoplasmic reticulum membrane,cellular_component
85963,GO:0098556,"The leaflet of the rough endoplasmic reticulum membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of rough endoplasmic reticulum membrane,cellular_component
85964,GO:0098557,"The leaflet of the smooth endoplasmic reticulum membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of smooth endoplasmic reticulum membrane,cellular_component
85965,GO:0098558,"The leaflet of the smooth endoplasmic reticulum membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of smooth endoplasmic reticulum membrane,cellular_component
85966,GO:0098559,"The leaflet of the early endosome membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of early endosome membrane,cellular_component
85967,GO:0098560,"The leaflet of the late endosome membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of late endosome membrane,cellular_component
85968,GO:0098561,"A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.",methyl accepting chemotaxis protein complex,cellular_component
85969,GO:0098562,"The leaflet of a membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of membrane,cellular_component
85970,GO:0098564,The volume enclosed within the membrane of a trans-Golgi network transport vesicle.,trans-Golgi network transport vesicle lumen,cellular_component
85971,GO:0098565,"The leaflet of the endosome membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of endosome membrane,cellular_component
85972,GO:0098566,The volume enclosed within the membrane of a transport vesicle.,transport vesicle lumen,cellular_component
85973,GO:0098567,"The leaflet of the plasma membrane that faces the periplasm, including any protein embedded in, attached to, or peripherally associated with it.",periplasmic side of plasma membrane,cellular_component
85974,GO:0098568,"The leaflet of the mycolate outer membrane that faces the periplasm of the cell, including any protein embedded in, attached to, or peripherally associated with it.",external side of mycolate outer membrane,cellular_component
85975,GO:0098569,"The leaflet of the mycolate outer membrane that faces the cell wall peptidoglycan, including any protein embedded in, attached to, or peripherally associated with it. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.",internal side of mycolate outer membrane,cellular_component
85976,GO:0098570,"The leaflet of the plastid inner membrane that faces the stroma, including any protein embedded in, attached to, or peripherally associated with it.",stromal side of plastid inner membrane,cellular_component
85977,GO:0098571,"The leaflet of a plastid thylakoid membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of plastid thylakoid membrane,cellular_component
85978,GO:0098572,"The leaflet of the plastid thylakoid membrane that faces the stroma, including any protein embedded in, attached to, or peripherally associated with it.",stromal side of plastid thylakoid membrane,cellular_component
85979,GO:0098574,"The leaflet of the lysosomal membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of lysosomal membrane,cellular_component
85980,GO:0098575,"The leaflet of the lysosomal membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of lysosomal membrane,cellular_component
85981,GO:0098576,"The leaflet of an organelle membrane that faces the lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of membrane,cellular_component
85982,GO:0098577,A sex chromosome that has been inactivated.,inactive sex chromosome,cellular_component
85983,GO:0098578,A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.,condensed chromatin of inactivated sex chromosome,cellular_component
85984,GO:0098579,A sex chromosome that has not been inactivated.,active sex chromosome,cellular_component
85985,GO:0098581,The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.,detection of external biotic stimulus,biological_process
85986,GO:0098582,"A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.",innate vocalization behavior,biological_process
85987,GO:0098583,A vocalization behavior that is the result of learning.,learned vocalization behavior,biological_process
85988,GO:0098584,"A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.",host cell synaptic vesicle,cellular_component
85989,GO:0098585,The lipid bilayer surrounding a host synaptic vesicle.,host cell synaptic vesicle membrane,cellular_component
85990,GO:0098586,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.",cellular response to virus,biological_process
85991,GO:0098588,The lipid bilayer that forms the outer-most layer of an organelle.,bounding membrane of organelle,cellular_component
85992,GO:0098590,A membrane that is a (regional) part of the plasma membrane.,plasma membrane region,cellular_component
85993,GO:0098591,"The leaflet the apical region of the plasma membrane that faces the extracellular side of the cell, including any protein embedded in, attached to, or peripherally associated with it.",external side of apical plasma membrane,cellular_component
85994,GO:0098592,"The leaflet of the apical region of the plasma membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of apical plasma membrane,cellular_component
85995,GO:0098593,"A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles r...",goblet cell theca,cellular_component
85996,GO:0098594,A secretory granule that contains mucin.,mucin granule,cellular_component
85997,GO:0098595,The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).,perivitelline space,cellular_component
85998,GO:0098596,Learning in which new behaviors are acquired through imitation.,imitative learning,biological_process
85999,GO:0098597,Learning that occurs through observing the behavior of others.,observational learning,biological_process
86000,GO:0098598,"Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.",learned vocalization behavior or vocal learning,biological_process
86001,GO:0098599,Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.,palmitoyl hydrolase activity,molecular_function
86002,GO:0098600,Catalysis of the reaction: L-Selenomethionine + H2O = Methaneselenol + Ammonia + 2-oxobutanoic acid.,selenomethionine gamma-lyase activity,molecular_function
86003,GO:0098601,Catalysis of the reaction: L-selenomethionine + ATP + H2O = L-adenosylselenomethionine + phosphate + diphosphate.,selenomethionine adenosyltransferase activity,molecular_function
86004,GO:0098603,Catalysis of the reaction: R + Se-Adenosylselenomethionine = CH3-R + Se-Adenosyl-L-selenohomocysteine.,selenol Se-methyltransferase activity,molecular_function
86005,GO:0098604,Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O = Adenosine + Selenohomocysteine.,adenosylselenohomocysteinase activity,molecular_function
86006,GO:0098605,Catalysis of the reaction: L-Serine + Selenohomocysteine = L-Selenocystathionine + H2O.,selenocystathionine beta-synthase activity,molecular_function
86007,GO:0098606,Catalysis of the reaction:L-selenocystathionine + H2O = L-selenocysteine + 2-oxobutanoate + NH4+.,selenocystathionine gamma-lyase activity,molecular_function
86008,GO:0098608,Catalysis of the reaction: methylselenol + H2O = H2Se + CH3OH.,methylselenol demethylase activity,molecular_function
86009,GO:0098609,The attachment of one cell to another cell via adhesion molecules.,cell-cell adhesion,biological_process
86010,GO:0098610,The attachment of two unicellular organisms to each other.,adhesion between unicellular organisms,biological_process
86011,GO:0098613,Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol = S-adenosyl-L-homocysteine + dimethyl selenide.,methaneselenol methyltransferase activity,molecular_function
86012,GO:0098614,Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide = S-adenosyl-L-homocysteine + methaneselenol.,hydrogen selenide methyltransferase activity,molecular_function
86013,GO:0098615,Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide = S-adenosyl-L-homocysteine + trimethylselenonium.,dimethyl selenide methyltransferase activity,molecular_function
86014,GO:0098616,Catalysis of the reaction: ATP + H2SeO4 = diphosphate + adenylylselenate.,selenate adenylyltransferase (ATP) activity,molecular_function
86015,GO:0098617,Catalysis of the reaction: ATP + adenylylselenate = ADP + 3'-phosphoadenylylselenate.,adenylylselenate kinase activity,molecular_function
86016,GO:0098618,Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) = AMP + diphosphate + selenomethionyl-tRNA(Met).,selenomethionine-tRNA ligase activity,molecular_function
86017,GO:0098619,Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.,selenocysteine-tRNA ligase activity,molecular_function
86018,GO:0098620,Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.,seryl-selenocysteinyl-tRNA kinase activity,molecular_function
86019,GO:0098621,Catalysis of the reaction: O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate.,O-phosphoseryl-tRNA(Sec) selenium transferase activity,molecular_function
86020,GO:0098622,Catalysis of the reaction: H+ + selenodiglutathione + NADPH = gluthathioselenol + glutathione + NADP+.,selenodiglutathione-disulfide reductase (NADPH) activity,molecular_function
86021,GO:0098623,Catalysis of the reaction: SeO3(2-) + 3 NADPH + 5H+ = H2Se +  3NADP+ + 3H2O.,selenite reductase (NADPH) activity,molecular_function
86022,GO:0098624,"Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH = adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.",3'-phosphoadenylylselenate reductase activity,molecular_function
86023,GO:0098625,Catalysis of the reaction: NADPH + H+ + CH3SeOH = NADP+ + CH3SeH + H2O.,methylselenol reductase activity,molecular_function
86024,GO:0098626,Catalysis of the reaction: NADPH + H+ + CH3SeO2H = NADP+ + CH3SeOH + H2O.,methylseleninic acid reductase activity,molecular_function
86025,GO:0098627,Catalysis of the reaction: phospho-L-arginyl-[protein] +H2O = L-arginyl-[protein] + phosphate.,protein arginine phosphatase activity,molecular_function
86026,GO:0098628,The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.,peptidyl-N-phospho-arginine dephosphorylation,biological_process
86027,GO:0098629,"A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.",trans-Golgi network membrane organization,biological_process
86028,GO:0098630,The clustering together of unicellular organisms in suspension form aggregates.,aggregation of unicellular organisms,biological_process
86029,GO:0098631,"The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.",cell adhesion mediator activity,molecular_function
86030,GO:0098632,"The binding by a cell-adhesion protein on the cell surface to an extracellular component of a different cell, to mediate adhesion of the cell to another cell.",cell-cell adhesion mediator activity,molecular_function
86031,GO:0098633,Binding to a collagen fibril.,collagen fibril binding,molecular_function
86032,GO:0098634,"The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix.",cell-matrix adhesion mediator activity,molecular_function
86033,GO:0098635,Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.,protein complex involved in cell-cell adhesion,cellular_component
86034,GO:0098636,Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.,protein complex involved in cell adhesion,cellular_component
86035,GO:0098637,Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.,protein complex involved in cell-matrix adhesion,cellular_component
86036,GO:0098638,Any laminin protein binding that occurs as part of cell-matrix adhesion.,laminin binding involved in cell-matrix adhesion,molecular_function
86037,GO:0098639,Any collagen binding that occurs as part of cell-matrix adhesion.,collagen binding involved in cell-matrix adhesion,molecular_function
86038,GO:0098640,Any integrin binding that occurs as part of the process of cell-matrix adhesion.,integrin binding involved in cell-matrix adhesion,molecular_function
86039,GO:0098641,Any cadherin binding that occurs as part of the process of cell-cell adhesion.,cadherin binding involved in cell-cell adhesion,molecular_function
86040,GO:0098642,A collagen trimer that forms networks.,network-forming collagen trimer,cellular_component
86041,GO:0098643,A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).,fibrillar collagen complex,cellular_component
86042,GO:0098644,A complex of collagen trimers such as a fibril or collagen network.,complex of collagen trimers,cellular_component
86043,GO:0098645,A supramolecular complex that consists of collagen triple helices associated to form a network.,complex of network-forming collagens,cellular_component
86044,GO:0098646,"A hexagonal-shaped collagen network formed by collagen type X trimer or collagen type VIII trimers. Collagen type X trimers are mostly found in the cartilage hyaline matrix, which is located in the interstitial area. Note that collagen type VIII has been found in the basement membrane, but the localization is not definitive.",hexagonal collagen network,cellular_component
86045,GO:0098647,A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure.,collagen beaded filament,cellular_component
86046,GO:0098648,"A specialised collagen fibril that functions as an anchor, binding to other collagen structures.",collagen anchoring fibril,cellular_component
86047,GO:0098650,Binding to a peptidyl-proline 4-dioxygenase.,peptidyl-proline 4-dioxygenase binding,molecular_function
86048,GO:0098653,The process by which centromeres/kinetochores become localized to clusters.,centromere clustering,biological_process
86049,GO:0098654,A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.,CENP-A recruiting complex,cellular_component
86050,GO:0098655,The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.,monoatomic cation transmembrane transport,biological_process
86051,GO:0098656,The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom.,monoatomic anion transmembrane transport,biological_process
86052,GO:0098657,The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.,import into cell,biological_process
86053,GO:0098658,"The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.",inorganic anion import across plasma membrane,biological_process
86054,GO:0098659,"The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.",inorganic cation import across plasma membrane,biological_process
86055,GO:0098664,The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.,G protein-coupled serotonin receptor signaling pathway,biological_process
86056,GO:0098665,A protein complex that is capable of serotonin receptor activity.,serotonin receptor complex,cellular_component
86057,GO:0098666,A protein complex that is capable of G protein-coupled serotonin receptor activity.,G protein-coupled serotonin receptor complex,cellular_component
86058,GO:0098669,"The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.",superinfection exclusion,biological_process
86059,GO:0098670,The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.,entry receptor-mediated virion attachment to host cell,biological_process
86060,GO:0098671,"The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located.",adhesion receptor-mediated virion attachment to host cell,biological_process
86061,GO:0098672,"A process by which a symbiont inhibits or disrupts the CRISPR-cas system of its host. Bacteria and archaea use CRISPR-Cas adaptive immune systems to defend themselves from infection by bacteriophages (phages), and phages have various mechanisms to counter the CRISPR-cas system.",symbiont-mediated suppression of host CRISPR-cas system,biological_process
86062,GO:0098673,"Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication.",symbiont-mediated suppression of host DNA replication,biological_process
86063,GO:0098674,"The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of neuronal dense core vesicle membrane,cellular_component
86064,GO:0098676,"A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses.",symbiont-mediated modulation of host virulence,biological_process
86065,GO:0098677,"Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.",virion maturation,biological_process
86066,GO:0098678,A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase.,viral tropism switching,biological_process
86067,GO:0098680,Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template.,template-free RNA nucleotidyltransferase activity,molecular_function
86068,GO:0098681,"A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical.",synaptic ribbon,cellular_component
86069,GO:0098682,An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane.,arciform density,cellular_component
86070,GO:0098683,A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.,cochlear hair cell ribbon synapse,cellular_component
86071,GO:0098684,A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon.,photoreceptor ribbon synapse,cellular_component
86072,GO:0098685,A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.,Schaffer collateral - CA1 synapse,cellular_component
86073,GO:0098686,"One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.",hippocampal mossy fiber to CA3 synapse,cellular_component
86074,GO:0098687,Any subdivision of a chromosome along its length.,chromosomal region,cellular_component
86075,GO:0098688,An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.,parallel fiber to Purkinje cell synapse,cellular_component
86076,GO:0098689,"The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic switch controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.",latency-replication decision,biological_process
86077,GO:0098690,A synapse that uses glycine as a neurotransmitter.,glycinergic synapse,cellular_component
86078,GO:0098691,A synapse that uses dopamine as a neurotransmitter.,dopaminergic synapse,cellular_component
86079,GO:0098692,A synapse that uses noradrenaline as a neurotransmitter.,noradrenergic synapse,cellular_component
86080,GO:0098693,"Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.",regulation of synaptic vesicle cycle,biological_process
86081,GO:0098694,"Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.",regulation of synaptic vesicle budding from presynaptic endocytic zone membrane,biological_process
86082,GO:0098695,"Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.","inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels",molecular_function
86083,GO:0098696,"Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.",regulation of neurotransmitter receptor localization to postsynaptic specialization membrane,biological_process
86084,GO:0098698,"The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.",postsynaptic specialization assembly,biological_process
86085,GO:0098699,The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.,structural constituent of presynaptic actin cytoskeleton,molecular_function
86086,GO:0098700,"The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps.",neurotransmitter loading into synaptic vesicle,biological_process
86087,GO:0098702,"The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.",adenine import across plasma membrane,biological_process
86088,GO:0098703,"The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.",calcium ion import across plasma membrane,biological_process
86089,GO:0098704,"The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.",carbohydrate import across plasma membrane,biological_process
86090,GO:0098705,"The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.",copper ion import across plasma membrane,biological_process
86091,GO:0098706,"The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space.",iron ion import across cell outer membrane,biological_process
86092,GO:0098708,"The directed movement of D-glucose from outside of a cell, across the plasma membrane and into the cytosol.",D-glucose import across plasma membrane,biological_process
86093,GO:0098709,"The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.",glutathione import across plasma membrane,biological_process
86094,GO:0098710,"The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.",guanine import across plasma membrane,biological_process
86095,GO:0098711,"The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.",iron ion import across plasma membrane,biological_process
86096,GO:0098712,"The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.",L-glutamate import across plasma membrane,biological_process
86097,GO:0098714,"The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.",malate import across plasma membrane,biological_process
86098,GO:0098715,"The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.",malonic acid import across plasma membrane,biological_process
86099,GO:0098716,"The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.",nickel cation import across plasma membrane,biological_process
86100,GO:0098717,"The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.",pantothenate import across plasma membrane,biological_process
86101,GO:0098718,"The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol.",serine import across plasma membrane,biological_process
86102,GO:0098719,"The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.",sodium ion import across plasma membrane,biological_process
86103,GO:0098720,"The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.",succinate import across plasma membrane,biological_process
86104,GO:0098721,"The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.",uracil import across plasma membrane,biological_process
86105,GO:0098722,Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.,asymmetric stem cell division,biological_process
86106,GO:0098723,A myofibril of a skeletal muscle fiber.,skeletal muscle myofibril,cellular_component
86107,GO:0098724,Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.,symmetric stem cell division,biological_process
86108,GO:0098725,Cell division in which both daughter cells are of the same type.,symmetric cell division,biological_process
86109,GO:0098726,"The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells.",symmetric division of skeletal muscle satellite stem cell,biological_process
86110,GO:0098727,Any process by which the numbers of cells of a particular type or in a tissue are maintained.,maintenance of cell number,biological_process
86111,GO:0098728,"The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.",germline stem cell asymmetric division,biological_process
86112,GO:0098729,Division of a germline stem cell to produce two germline stem cells of the same type as the parent.,germline stem cell symmetric division,biological_process
86113,GO:0098730,"The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.",male germline stem cell symmetric division,biological_process
86114,GO:0098732,"The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.",macromolecule deacylation,biological_process
86115,GO:0098733,Any protein complex that is part of or has some part in a hemidesmosome.,hemidesmosome associated protein complex,cellular_component
86116,GO:0098734,The removal of palymitoyl groups from a macromolecule.,macromolecule depalmitoylation,biological_process
86117,GO:0098735,Any process that increases the force of heart muscle contraction.,positive regulation of the force of heart contraction,biological_process
86118,GO:0098736,Any process that decreases the force of heart muscle contraction.,negative regulation of the force of heart contraction,biological_process
86119,GO:0098737,The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.,protein insertion into plasma membrane,biological_process
86120,GO:0098739,"The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.",import across plasma membrane,biological_process
86121,GO:0098743,The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.,cell aggregation,biological_process
86122,GO:0098744,Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.,1-phosphatidylinositol 4-kinase activator activity,molecular_function
86123,GO:0098745,A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.,RNA decapping complex,cellular_component
86124,GO:0098746,"The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.","fast, calcium ion-dependent exocytosis of neurotransmitter",biological_process
86125,GO:0098747,"The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.","slow, calcium ion-dependent exocytosis of neurotransmitter",biological_process
86126,GO:0098749,"The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",cerebellar neuron development,biological_process
86127,GO:0098750,Binding to a FXYD domain.,FYXD domain binding,molecular_function
86128,GO:0098751,"The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.",bone cell development,biological_process
86129,GO:0098754,Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,detoxification,biological_process
86130,GO:0098755,The process by which seed dormancy is maintained by the presence of absisic acid.,maintenance of seed dormancy by absisic acid,biological_process
86131,GO:0098756,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.",response to interleukin-21,biological_process
86132,GO:0098757,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.",cellular response to interleukin-21,biological_process
86133,GO:0098758,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.",response to interleukin-8,biological_process
86134,GO:0098759,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.",cellular response to interleukin-8,biological_process
86135,GO:0098760,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.",response to interleukin-7,biological_process
86136,GO:0098761,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.",cellular response to interleukin-7,biological_process
86137,GO:0098762,One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.,meiotic cell cycle phase,biological_process
86138,GO:0098763,One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.,mitotic cell cycle phase,biological_process
86139,GO:0098764,A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.,meiosis I cell cycle phase,biological_process
86140,GO:0098765,A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).,meiosis II cell cycle phase,biological_process
86141,GO:0098768,"The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.",meiotic prometaphase I,biological_process
86142,GO:0098769,Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.,TIMP family protein binding,molecular_function
86143,GO:0098770,Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.,FBXO family protein binding,molecular_function
86144,GO:0098771,Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.,inorganic ion homeostasis,biological_process
86145,GO:0098772,A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.,molecular function regulator activity,molecular_function
86146,GO:0098773,"The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.",skin epidermis development,biological_process
86147,GO:0098774,"A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.",curli,cellular_component
86148,GO:0098775,"The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.",curli assembly,biological_process
86149,GO:0098776,The directed movement of proteins across the cell outer membrane.,protein transport across the cell outer membrane,biological_process
86150,GO:0098777,Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.,protein secretion by the type VIII secretion system,biological_process
86151,GO:0098778,"The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.",curli subunit secretion coupled to curli assembly,biological_process
86152,GO:0098780,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.",response to mitochondrial depolarisation,biological_process
86153,GO:0098782,Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.,mechanosensitive potassium channel activity,molecular_function
86154,GO:0098784,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.",biofilm matrix organization,biological_process
86155,GO:0098785,A process that results in the assembly of a biofilm matrix.,biofilm matrix assembly,biological_process
86156,GO:0098786,A process that results in the disassembly of a biofilm matrix.,biofilm matrix disassembly,biological_process
86157,GO:0098788,"The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.",dendritic knob,cellular_component
86158,GO:0098791,"A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.",Golgi apparatus subcompartment,cellular_component
86159,GO:0098792,The selective degradation of intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) by macroautophagy.,xenophagy,biological_process
86160,GO:0098793,The part of a synapse that is part of the presynaptic cell.,presynapse,cellular_component
86161,GO:0098794,The part of a synapse that is part of the post-synaptic cell.,postsynapse,cellular_component
86162,GO:0098795,A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner.,global gene silencing by mRNA cleavage,biological_process
86163,GO:0098796,Any protein complex that is part of a membrane.,membrane protein complex,cellular_component
86164,GO:0098797,Any protein complex that is part of the plasma membrane.,plasma membrane protein complex,cellular_component
86165,GO:0098798,A protein complex that is part of a mitochondrion.,mitochondrial protein-containing complex,cellular_component
86166,GO:0098799,Any protein complex that is part of the outer mitochondrial membrane.,outer mitochondrial membrane protein complex,cellular_component
86167,GO:0098800,Any protein complex that is part of the inner mitochondrial membrane.,inner mitochondrial membrane protein complex,cellular_component
86168,GO:0098801,"Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.",regulation of renal system process,biological_process
86169,GO:0098802,Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.,plasma membrane signaling receptor complex,cellular_component
86170,GO:0098803,Any protein complex that is part of a respiratory chain.,respiratory chain complex,cellular_component
86171,GO:0098804,The portion of the plasma membrane surrounding a non-motile cilium.,non-motile cilium membrane,cellular_component
86172,GO:0098807,A protein complex that is part of a chloroplast thylakoid membrane.,chloroplast thylakoid membrane protein complex,cellular_component
86173,GO:0098808,Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.,mRNA cap binding,molecular_function
86174,GO:0098809,Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor.,nitrite reductase activity,molecular_function
86175,GO:0098810,The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol.,neurotransmitter reuptake,biological_process
86176,GO:0098813,"The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.",nuclear chromosome segregation,biological_process
86177,GO:0098814,The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.,spontaneous synaptic transmission,biological_process
86178,GO:0098815,"Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.",modulation of excitatory postsynaptic potential,biological_process
86179,GO:0098816,"A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.",mini excitatory postsynaptic potential,biological_process
86180,GO:0098817,A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.,evoked excitatory postsynaptic potential,biological_process
86181,GO:0098818,"A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.",hyperpolarization of postsynaptic membrane,biological_process
86182,GO:0098819,"A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.",depolarization of postsynaptic membrane,biological_process
86183,GO:0098820,A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.,trans-synaptic protein complex,cellular_component
86184,GO:0098821,"Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.",BMP receptor activity,molecular_function
86185,GO:0098826,The membrane of the endoplasmic reticulum tubular network.,endoplasmic reticulum tubular network membrane,cellular_component
86186,GO:0098827,A distinct region of the endoplasmic reticulum.,endoplasmic reticulum subcompartment,cellular_component
86187,GO:0098828,"Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.",modulation of inhibitory postsynaptic potential,biological_process
86188,GO:0098829,Uptake of folic into the blood by absorption from the small intestine.,intestinal folate absorption,biological_process
86189,GO:0098830,An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles.,presynaptic endosome,cellular_component
86190,GO:0098831,"A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles.",presynaptic active zone cytoplasmic component,cellular_component
86191,GO:0098832,"A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.",peri-centrosomal recycling endosome,cellular_component
86192,GO:0098833,"A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity.",presynaptic endocytic zone,cellular_component
86193,GO:0098834,The cytoplasmic component of the presynaptic endocytic zone.,presynaptic endocytic zone cytoplasmic component,cellular_component
86194,GO:0098835,The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.,presynaptic endocytic zone membrane,cellular_component
86195,GO:0098836,The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodeling in response to postsynaptic signaling.,cytoskeleton of dendritic spine,cellular_component
86196,GO:0098837,"A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signaling and so can play a role in long term potentiation.",postsynaptic recycling endosome,cellular_component
86197,GO:0098838,"The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane.",folate transmembrane transport,biological_process
86198,GO:0098839,The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.,postsynaptic density membrane,cellular_component
86199,GO:0098840,"The directed movement of a protein along a microtubule, mediated by motor proteins.",protein transport along microtubule,biological_process
86200,GO:0098841,"A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.",protein localization to cell division site after cytokinesis,biological_process
86201,GO:0098842,"An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.",postsynaptic early endosome,cellular_component
86202,GO:0098843,"A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins.",postsynaptic endocytic zone,cellular_component
86203,GO:0098844,The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.,postsynaptic endocytic zone membrane,cellular_component
86204,GO:0098845,An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.,postsynaptic endosome,cellular_component
86205,GO:0098846,"A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.",podocyte foot,cellular_component
86206,GO:0098847,Binding to single-stranded DNA of a specific nucleotide composition.,sequence-specific single stranded DNA binding,molecular_function
86207,GO:0098848,"Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.",alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity,molecular_function
86208,GO:0098849,Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.,cellular detoxification of cadmium ion,biological_process
86209,GO:0098850,"The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of synaptic vesicle membrane,cellular_component
86210,GO:0098851,Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.,double-stranded miRNA binding,molecular_function
86211,GO:0098852,The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.,lytic vacuole membrane,cellular_component
86212,GO:0098853,"A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.",endoplasmic reticulum-vacuole membrane contact site,cellular_component
86213,GO:0098854,A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.,podocyte primary projection,cellular_component
86214,GO:0098855,"A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.",HCN channel complex,cellular_component
86215,GO:0098856,A process in which lipids are taken up from the contents of the intestine.,intestinal lipid absorption,biological_process
86216,GO:0098857,A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.,membrane microdomain,cellular_component
86217,GO:0098858,"A cell projection supported by an assembly of actin filaments, and which lacks microtubules.",actin-based cell projection,cellular_component
86218,GO:0098859,"A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments.",actin filament bundle of actin-based cell projection,cellular_component
86219,GO:0098860,"A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.",actin filament bundle of stereocilium,cellular_component
86220,GO:0098861,"A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.",actin filament bundle of filopodium,cellular_component
86221,GO:0098862,"A cell part consisting of multiple, closely packed actin-based cell projections.",cluster of actin-based cell projections,cellular_component
86222,GO:0098863,The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.,nuclear migration by microtubule mediated pushing forces,biological_process
86223,GO:0098864,"The process in which a symbiont organism that stabilizes the its host tight cell-cell junctions, making them less dynamic. The tight junction is a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other, and plays a role in the inflammatory response of the host.",symbiont-mediated stabilization of host tight cell-cell junction,biological_process
86224,GO:0098865,"The process in which an organism effects a change that impairs the structure or temporarily subverts the tight cell-cell junctions between cells of the host. Tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.",symbiont-mediated perturbation of host tight cell-cell junction,biological_process
86225,GO:0098866,"The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.",multivesicular body fusion to apical plasma membrane,biological_process
86226,GO:0098867,The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.,intramembranous bone growth,biological_process
86227,GO:0098868,The increase in size or mass of a bone that contributes to the shaping of that bone.,bone growth,biological_process
86228,GO:0098869,Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.,cellular oxidant detoxification,biological_process
86229,GO:0098870,The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold.,action potential propagation,biological_process
86230,GO:0098871,The actin cytoskeleton that is part of a postsynapse.,postsynaptic actin cytoskeleton,cellular_component
86231,GO:0098873,"Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.",neuronal action potential back-propagation,biological_process
86232,GO:0098874,"A series of sequential, propagated action potentials occurring in a single cell.",spike train,biological_process
86233,GO:0098875,"A microvesicle of the epididymal fluid, from which spermatozoa acquire membrane proteins.",epididymosome,cellular_component
86234,GO:0098876,The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.,vesicle-mediated transport to the plasma membrane,biological_process
86235,GO:0098877,The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.,neurotransmitter receptor transport to plasma membrane,biological_process
86236,GO:0098878,Any protein complex that is capable of functioning as a neurotransmitter receptor.,neurotransmitter receptor complex,cellular_component
86237,GO:0098879,The action of a molecule that contributes to the structural integrity of a postsynaptic specialization.,structural constituent of postsynaptic specialization,molecular_function
86238,GO:0098880,A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.,maintenance of postsynaptic specialization structure,biological_process
86239,GO:0098882,The action of a molecule that contributes to the structural integrity of a presynaptic active zone.,structural constituent of presynaptic active zone,molecular_function
86240,GO:0098883,A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.,synapse pruning,biological_process
86241,GO:0098884,A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.,postsynaptic neurotransmitter receptor internalization,biological_process
86242,GO:0098885,Any process that modifies the structure of a postsynaptic actin cytoskeleton.,modification of postsynaptic actin cytoskeleton,biological_process
86243,GO:0098886,Any process that modifies the structure of a dendritic spine.,modification of dendritic spine,biological_process
86244,GO:0098887,The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.,"neurotransmitter receptor transport, endosome to postsynaptic membrane",biological_process
86245,GO:0098888,"The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of presynaptic membrane,cellular_component
86246,GO:0098890,"The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic membrane,cellular_component
86247,GO:0098891,"The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of presynaptic active zone membrane,cellular_component
86248,GO:0098892,"The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic specialization membrane,cellular_component
86249,GO:0098893,"The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic endocytic zone,cellular_component
86250,GO:0098894,"The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of presynaptic endocytic zone membrane,cellular_component
86251,GO:0098895,The lipid bilayer surrounding a postsynaptic endosome.,postsynaptic endosome membrane,cellular_component
86252,GO:0098896,The lipid bilayer surrounding a postsynaptic early endosome.,postsynaptic early endosome membrane,cellular_component
86253,GO:0098897,The lipid bilayer surrounding the spine apparatus.,spine apparatus membrane,cellular_component
86254,GO:0098898,The volume enclosed by the dense core granule membrane.,dense core granule lumen,cellular_component
86255,GO:0098899,The volume enclosed by the spine apparatus membrane.,spine apparatus lumen,cellular_component
86256,GO:0098900,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of action potential,biological_process
86257,GO:0098901,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of cardiac muscle cell action potential,biological_process
86258,GO:0098902,"Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.",regulation of membrane depolarization during action potential,biological_process
86259,GO:0098903,"Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.",regulation of membrane repolarization during action potential,biological_process
86260,GO:0098904,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of AV node cell action potential,biological_process
86261,GO:0098905,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of bundle of His cell action potential,biological_process
86262,GO:0098906,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of Purkinje myocyte action potential,biological_process
86263,GO:0098907,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of SA node cell action potential,biological_process
86264,GO:0098908,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of neuronal action potential,biological_process
86265,GO:0098909,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.",regulation of cardiac muscle cell action potential involved in regulation of contraction,biological_process
86266,GO:0098910,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of atrial cardiac muscle cell action potential,biological_process
86267,GO:0098911,"Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.",regulation of ventricular cardiac muscle cell action potential,biological_process
86268,GO:0098912,The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during atrial cardiac muscle cell action potential,biological_process
86269,GO:0098913,The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.,membrane depolarization during ventricular cardiac muscle cell action potential,biological_process
86270,GO:0098914,The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during atrial cardiac muscle cell action potential,biological_process
86271,GO:0098915,The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.,membrane repolarization during ventricular cardiac muscle cell action potential,biological_process
86272,GO:0098916,"Cell-cell signaling from pre to post-synapse, across the synaptic cleft.",anterograde trans-synaptic signaling,biological_process
86273,GO:0098917,"Cell-cell signaling from post to pre-synapse, across the synaptic cleft.",retrograde trans-synaptic signaling,biological_process
86274,GO:0098918,The action of a molecule that contributes to the structural integrity of a synapse.,structural constituent of synapse,molecular_function
86275,GO:0098919,The action of a molecule that contributes to the structural integrity of a postsynaptic density.,structural constituent of postsynaptic density,molecular_function
86276,GO:0098920,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.",retrograde trans-synaptic signaling by lipid,biological_process
86277,GO:0098921,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand.",retrograde trans-synaptic signaling by endocannabinoid,biological_process
86278,GO:0098922,"The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of dense core granule membrane,cellular_component
86279,GO:0098923,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.",retrograde trans-synaptic signaling by soluble gas,biological_process
86280,GO:0098924,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.",retrograde trans-synaptic signaling by nitric oxide,biological_process
86281,GO:0098925,"Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.","retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission",biological_process
86282,GO:0098926,Signal transduction in which the initial step occurs in a postsynapse.,postsynaptic signal transduction,biological_process
86283,GO:0098927,"A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.",vesicle-mediated transport between endosomal compartments,biological_process
86284,GO:0098928,Signal transduction in which the initial step occurs in a presynapse.,presynaptic signal transduction,biological_process
86285,GO:0098930,The directed movement of organelles or molecules along microtubules in axons.,axonal transport,biological_process
86286,GO:0098931,The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.,virion attachment to host cell flagellum,biological_process
86287,GO:0098932,The disruption by a symbiont of host cell wall peptidoglycans to allow entry into the host cell.,symbiont entry into host cell via disruption of host cell wall peptidoglycan,biological_process
86288,GO:0098933,The process in which a symbiont effects a change that impairs the structure or function of the host cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cell envelope,biological_process
86289,GO:0098934,The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.,retrograde dendritic transport,biological_process
86290,GO:0098935,The directed movement of organelles or molecules along microtubules in dendrites.,dendritic transport,biological_process
86291,GO:0098937,The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.,anterograde dendritic transport,biological_process
86292,GO:0098938,The actin cytoskeleton that is part of a dendritic spine.,actin cytoskeleton of dendritic spine,cellular_component
86293,GO:0098939,The directed movement of mitochondria along microtubules in nerve cell dendrites.,dendritic transport of mitochondrion,biological_process
86294,GO:0098940,"Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.",anterograde trans-synaptic signaling by nitric oxide,biological_process
86295,GO:0098941,"Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.",anterograde trans-synaptic signaling by trans-synaptic protein complex,biological_process
86296,GO:0098942,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.",retrograde trans-synaptic signaling by trans-synaptic protein complex,biological_process
86297,GO:0098943,The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.,"neurotransmitter receptor transport, postsynaptic endosome to lysosome",biological_process
86298,GO:0098944,The lipid bilayer surrounding a postsynaptic recycling endosome.,postsynaptic recycling endosome membrane,cellular_component
86299,GO:0098953,"The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.",receptor diffusion trapping,biological_process
86300,GO:0098954,The lipid bilayer surrounding a presynaptic endosome.,presynaptic endosome membrane,cellular_component
86301,GO:0098957,The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.,anterograde axonal transport of mitochondrion,biological_process
86302,GO:0098958,The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.,retrograde axonal transport of mitochondrion,biological_process
86303,GO:0098959,The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.,retrograde dendritic transport of mitochondrion,biological_process
86304,GO:0098960,Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission.,postsynaptic neurotransmitter receptor activity,molecular_function
86305,GO:0098961,The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.,dendritic transport of ribonucleoprotein complex,biological_process
86306,GO:0098963,The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.,dendritic transport of messenger ribonucleoprotein complex,biological_process
86307,GO:0098964,The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.,anterograde dendritic transport of messenger ribonucleoprotein complex,biological_process
86308,GO:0098965,The portion of the extracellular matrix that lies within the synaptic cleft.,extracellular matrix of synaptic cleft,cellular_component
86309,GO:0098966,The portion of the extracellular matrix that lies within the perisynaptic space.,perisynaptic extracellular matrix,cellular_component
86310,GO:0098967,"The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.",exocytic insertion of neurotransmitter receptor to postsynaptic membrane,biological_process
86311,GO:0098968,Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.,neurotransmitter receptor transport postsynaptic membrane to endosome,biological_process
86312,GO:0098969,The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.,neurotransmitter receptor transport to postsynaptic membrane,biological_process
86313,GO:0098970,The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.,postsynaptic neurotransmitter receptor diffusion trapping,biological_process
86314,GO:0098971,The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.,anterograde dendritic transport of neurotransmitter receptor complex,biological_process
86315,GO:0098972,The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.,anterograde dendritic transport of mitochondrion,biological_process
86316,GO:0098973,The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.,structural constituent of postsynaptic actin cytoskeleton,molecular_function
86317,GO:0098974,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.",postsynaptic actin cytoskeleton organization,biological_process
86318,GO:0098975,"The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.",postsynapse of neuromuscular junction,cellular_component
86319,GO:0098976,Synaptic transmission that results in an excitatory postsynaptic potential.,excitatory chemical synaptic transmission,biological_process
86320,GO:0098977,Synaptic transmission that results in an inhibitory postsynaptic potential.,inhibitory chemical synaptic transmission,biological_process
86321,GO:0098978,A synapse that uses glutamate as a neurotransmitter.,glutamatergic synapse,cellular_component
86322,GO:0098979,A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.,polyadic synapse,cellular_component
86323,GO:0098980,An electron dense specialization of the presynaptic active zone cytoskeleton.,presynaptic density,cellular_component
86324,GO:0098981,A synapse that uses acetylcholine as a neurotransmitter.,cholinergic synapse,cellular_component
86325,GO:0098982,A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.,GABA-ergic synapse,cellular_component
86326,GO:0098983,"A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.","symmetric, GABA-ergic, inhibitory synapse",cellular_component
86327,GO:0098984,A synapse in which pre and post-synaptic cells are neurons.,neuron to neuron synapse,cellular_component
86328,GO:0098985,"A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.","asymmetric, glutamatergic, excitatory synapse",cellular_component
86329,GO:0098986,A T-shaped presynpatic density. These are common in arhropod central nervous systems.,T-bar,cellular_component
86330,GO:0098987,Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.,"regulation of modification of synapse structure, modulating synaptic transmission",biological_process
86331,GO:0098988,"Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.",G protein-coupled glutamate receptor activity,molecular_function
86332,GO:0098989,"The series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.",NMDA selective glutamate receptor signaling pathway,biological_process
86333,GO:0098990,"The series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.",AMPA selective glutamate receptor signaling pathway,biological_process
86334,GO:0098991,"The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription.",kainate selective glutamate receptor signaling pathway,biological_process
86335,GO:0098992,"A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.",neuronal dense core vesicle,cellular_component
86336,GO:0098994,The disruption by a symbiont of host cell envelope components to allow entry into the host cell.,symbiont entry into host cell via disruption of host cell envelope,biological_process
86337,GO:0098995,The disruption by a symbiont of host cell wall lipopolysaccharides to allow entry into the host cell. For example a phage entering a Gram-negative bacterium may actively break down outer membrane lipopolysaccharides.,symbiont entry into host cell via disruption of host cell envelope lipopolysaccharide,biological_process
86338,GO:0098996,The disruption by a symbiont of host cell capsule to allow entry into the host cell.,symbiont entry into host cell via disruption of host cell glycocalyx,biological_process
86339,GO:0098997,Fusion of a viral membrane with the host cell outer membrane during viral entry.,fusion of virus membrane with host outer membrane,biological_process
86340,GO:0098998,"The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic early endosome membrane,cellular_component
86341,GO:0098999,"The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic endosome membrane,cellular_component
86342,GO:0099000,"Entry of a symbiont's genome into the host cell through the host cell envelope via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope. Occurs in non-enveloped prokaryotic viruses.","symbiont genome ejection through host cell envelope, contractile tail mechanism",biological_process
86343,GO:0099001,"Entry of a symbiont's genome into the host cell through the host cell envelope via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm. Occurs in non-enveloped prokaryotic viruses.","symbiont genome ejection through host cell envelope, long flexible tail mechanism",biological_process
86344,GO:0099002,"Entry of a symbiont's genome into the host cell through the host cell envelope via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. Occurs in non-enveloped prokaryo...","symbiont genome ejection through host cell envelope, short tail mechanism",biological_process
86345,GO:0099003,Any vesicle-mediated transport that occurs in a synapse.,vesicle-mediated transport in synapse,biological_process
86346,GO:0099005,"The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic recycling endosome membrane,cellular_component
86347,GO:0099006,"The entry of a symbiont into a host cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) of the symbiont. This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.",symbiont entry into host cell via permeabilization of endosomal membrane,biological_process
86348,GO:0099007,"The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of presynaptic endosome membrane,cellular_component
86349,GO:0099008,"The entry of a symbiont into the cytoplasm of a host cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. This process mediates the entry of some non-enveloped viruses into prokaryotic cells. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization and permeabilization of the plasma membrane.",symbiont entry into host cell via permeabilization of inner membrane,biological_process
86350,GO:0099009,"The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities.",viral genome circularization,biological_process
86351,GO:0099010,Any process that modifies the structure of a postsynapse.,modification of postsynaptic structure,biological_process
86352,GO:0099011,"The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.",neuronal dense core vesicle exocytosis,biological_process
86353,GO:0099012,The lipid bilayer surrounding a neuronal dense core vesicle.,neuronal dense core vesicle membrane,cellular_component
86354,GO:0099013,The volume enclosed by a neuronal dense core vesicle membrane.,neuronal dense core vesicle lumen,cellular_component
86355,GO:0099014,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.",neuronal dense core vesicle organization,biological_process
86356,GO:0099015,The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.,degradation of host chromosome by virus,biological_process
86357,GO:0099016,"A process by which a symbiont evades and ends degradation of its DNA when free DNA ends are exposed. DNA ends are exposed during the life cycle of some viruses and these are targeted by host cells to destroy the virus. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases.",symbiont-mediated evasion of DNA end degradation by host,biological_process
86358,GO:0099017,Any process in which localization of a protein is maintained at the cell tip.,maintenance of protein localization at cell tip,biological_process
86359,GO:0099018,A process by which a symbiont evades the DNA restriction modification system of its host. This process occurs in phages to protein themselves from bacterial restriction enzyme systems. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restriction enzymes while some use unusual bases in their genome to avoid restriction.,symbiont-mediated evasion of host restriction-modification system,biological_process
86360,GO:0099019,Any process in which localization of a protein is maintained at the growing cell tip.,maintenance of protein localization at growing cell tip,biological_process
86361,GO:0099020,The volume enclosed by the membranes of the perinuclear endoplasmic reticulum.,perinuclear endoplasmic reticulum lumen,cellular_component
86362,GO:0099021,The volume enclosed by the membranes of the cortical endoplasmic reticulum.,cortical endoplasmic reticulum lumen,cellular_component
86363,GO:0099023,Any protein complex that plays a role in vesicle tethering.,vesicle tethering complex,cellular_component
86364,GO:0099024,An infolding of the plasma membrane.,plasma membrane invagination,biological_process
86365,GO:0099038,"Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",ceramide floppase activity,molecular_function
86366,GO:0099039,The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.,sphingolipid translocation,biological_process
86367,GO:0099040,The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.,ceramide translocation,biological_process
86368,GO:0099045,The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generat...,viral extrusion,biological_process
86369,GO:0099046,A defense process that protects an organism from DNA or RNA from an invading organism.,clearance of foreign intracellular nucleic acids,biological_process
86370,GO:0099047,A defense process that protects an organism from invading foreign RNA.,clearance of foreign intracellular RNA,biological_process
86371,GO:0099048,"A defense response of that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.",CRISPR-cas system,biological_process
86372,GO:0099049,The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.,clathrin coat assembly involved in endocytosis,biological_process
86373,GO:0099050,"The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.",vesicle scission,biological_process
86374,GO:0099051,The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.,vesicle scission involved in endocytosis,biological_process
86375,GO:0099054,"The aggregation, arrangement and bonding together of a set of components to form a presynapse.",presynapse assembly,biological_process
86376,GO:0099068,"The aggregation, arrangement and bonding together of a set of components to form a postsynapse.",postsynapse assembly,biological_process
86377,GO:0099070,"A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.",static microtubule bundle,cellular_component
86378,GO:0099071,"A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.",dynamic microtubule bundle,cellular_component
86379,GO:0099072,Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.,regulation of postsynaptic membrane neurotransmitter receptor levels,biological_process
86380,GO:0099073,"A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae.",mitochondrion-derived vesicle,cellular_component
86381,GO:0099074,"Vesicle-mediated transport of cargo from the mitochondrion to the lysosome, mediated by a mitochondrion-derived vesicle.",mitochondrion to lysosome vesicle-mediated transport,biological_process
86382,GO:0099075,Vesicle-mediated transport of cargo from the mitochondrion by a mitochondrion-derived vesicle.,mitochondrion-derived vesicle mediated transport,biological_process
86383,GO:0099076,"Vesicle-mediated transport of cargo from the mitochondrion to the peroxisome, mediated by a mitochondrion-derived vesicle.",mitochondrion to peroxisome vesicle-mediated transport,biological_process
86384,GO:0099077,DNA-binding activity that is dependent on binding to a histone.,histone-dependent DNA binding,molecular_function
86385,GO:0099078,"A protein complex that is involved in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.",BORC complex,cellular_component
86386,GO:0099079,An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.,actin body,cellular_component
86387,GO:0099080,"A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.",supramolecular complex,cellular_component
86388,GO:0099081,A polymeric supramolecular structure.,supramolecular polymer,cellular_component
86389,GO:0099082,"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.",retrograde trans-synaptic signaling by neuropeptide,biological_process
86390,GO:0099083,"Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.","retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission",biological_process
86391,GO:0099084,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.",postsynaptic specialization organization,biological_process
86392,GO:0099085,"Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one = 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.",DIF dechlorinase activity,molecular_function
86393,GO:0099086,A proteinaceous scaffold found between homologous chromosomes during meiosis.,synaptonemal structure,cellular_component
86394,GO:0099087,"The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse.",anterograde axonal transport of messenger ribonucleoprotein complex,biological_process
86395,GO:0099088,The directed movement of a messenger ribonucleoprotein complex along microtubules in axons.,axonal transport of messenger ribonucleoprotein complex,biological_process
86396,GO:0099089,The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.,establishment of endoplasmic reticulum localization to postsynapse,biological_process
86397,GO:0099091,"A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.","postsynaptic specialization, intracellular component",cellular_component
86398,GO:0099092,"A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.","postsynaptic density, intracellular component",cellular_component
86399,GO:0099093,"A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.",calcium export from the mitochondrion,biological_process
86400,GO:0099094,Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated monoatomic cation channel activity,molecular_function
86401,GO:0099095,Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated monoatomic anion channel activity,molecular_function
86402,GO:0099096,"The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell.",vestibular calyx terminal,cellular_component
86403,GO:0099098,The movement of a cellular component as a result of microtubule polymerization.,microtubule polymerization based movement,biological_process
86404,GO:0099099,An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.,G-protein gated monoatomic ion channel activity,molecular_function
86405,GO:0099100,A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.,G-protein gated monoatomic cation channel activity,molecular_function
86406,GO:0099101,A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer.,G-protein gated potassium channel activity,molecular_function
86407,GO:0099103,"Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.",channel activator activity,molecular_function
86408,GO:0099104,"Binds to and increases the activity of a potassium channel, resulting in its opening.",potassium channel activator activity,molecular_function
86409,GO:0099106,"Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.",ion channel regulator activity,molecular_function
86410,GO:0099110,"The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached.",microtubule polymerization based protein transport to cell tip cortex,biological_process
86411,GO:0099111,"A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.",microtubule-based transport,biological_process
86412,GO:0099112,The transport of a protein driven by polymerization of a microtubule to which it is attached.,microtubule polymerization based protein transport,biological_process
86413,GO:0099113,Any process that decreases the concentration of calcium ions in the presynaptic cytosol.,negative regulation of presynaptic cytosolic calcium concentration,biological_process
86414,GO:0099115,"A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin.","chromosome, subtelomeric region",cellular_component
86415,GO:0099116,The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.,tRNA 5'-end processing,biological_process
86416,GO:0099117,"The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins.",protein transport along microtubule to cell tip,biological_process
86417,GO:0099118,A microtubule-based process that results in the transport of proteins.,microtubule-based protein transport,biological_process
86418,GO:0099120,"The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.",socially cooperative development,biological_process
86419,GO:0099121,"The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.",fungal sorus development,biological_process
86420,GO:0099122,Binding to the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.,RNA polymerase II C-terminal domain binding,molecular_function
86421,GO:0099123,The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.,somato-dendritic dopamine secretion,biological_process
86422,GO:0099124,The regulated release of dopamine from an axon.,axonal dopamine secretion,biological_process
86423,GO:0099125,"A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network.",PAK family kinase-Sog2 complex,cellular_component
86424,GO:0099126,"A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP.",transforming growth factor beta complex,cellular_component
86425,GO:0099128,"A protein complex capable of forming 2Fe-2S clusters in mitochondria. In humans it consists of ISCU, NFS1, LYRM4, NDUFAB1 and FXN.",mitochondrial [2Fe-2S] assembly complex,cellular_component
86426,GO:0099129,"A rapid, force generating length change of an outer hair cell in response to electrical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification.",cochlear outer hair cell electromotile response,biological_process
86427,GO:0099130,Binding to an estrogen.,estrogen binding,molecular_function
86428,GO:0099134,Development of a sorocarp formed by aggregation of cells with different genotypes.,chimeric sorocarp development,biological_process
86429,GO:0099135,"Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.",chimeric colonial development,biological_process
86430,GO:0099136,Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.,chimeric non-reproductive fruiting body development,biological_process
86431,GO:0099137,"Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.","altruistic, chimeric, non-reproductive fruiting body development",biological_process
86432,GO:0099138,Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.,"altruistic, chimeric sorocarp development",biological_process
86433,GO:0099139,Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.,cheating during chimeric sorocarp development,biological_process
86434,GO:0099140,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.",presynaptic actin cytoskeleton organization,biological_process
86435,GO:0099141,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.",cellular response to protozoan,biological_process
86436,GO:0099142,Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.,intracellularly ATP-gated ion channel activity,molecular_function
86437,GO:0099143,The actin cytoskeleton that is part of a presynapse.,presynaptic actin cytoskeleton,cellular_component
86438,GO:0099145,"Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.",regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane,biological_process
86439,GO:0099147,"The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of postsynaptic density membrane,cellular_component
86440,GO:0099149,"Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.",regulation of postsynaptic neurotransmitter receptor internalization,biological_process
86441,GO:0099150,"Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.",regulation of postsynaptic specialization assembly,biological_process
86442,GO:0099151,"Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.",regulation of postsynaptic density assembly,biological_process
86443,GO:0099152,"Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.","regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane",biological_process
86444,GO:0099153,"The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival...","synaptic transmission, serotonergic",biological_process
86445,GO:0099154,A synapse that uses serotonin as a neurotransmitter.,serotonergic synapse,cellular_component
86446,GO:0099155,"The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission sta...","synaptic transmission, noradrenergic",biological_process
86447,GO:0099156,Cell-cell signaling in which the ligand is carried between cells by an exosome.,cell-cell signaling via exosome,biological_process
86448,GO:0099157,Transynaptic signaling in which the ligand is carried across the synapse by an exosome.,trans-synaptic signaling via exosome,biological_process
86449,GO:0099158,"Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.",regulation of recycling endosome localization within postsynapse,biological_process
86450,GO:0099159,"Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.",regulation of modification of postsynaptic structure,biological_process
86451,GO:0099160,The intermediate filament cytoskeleton that is part of a postsynapse.,postsynaptic intermediate filament cytoskeleton,cellular_component
86452,GO:0099161,"Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.",regulation of presynaptic dense core granule exocytosis,biological_process
86453,GO:0099162,"Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.",regulation of neurotransmitter loading into synaptic vesicle,biological_process
86454,GO:0099163,"Cell-cell signaling to or from a synapse, mediated by nitric oxide.",synaptic signaling by nitric oxide,biological_process
86455,GO:0099164,The membrane component of the postsynaptic specialization of a symmetric synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.,postsynaptic specialization membrane of symmetric synapse,cellular_component
86456,GO:0099165,"A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses.","postsynaptic specialization of symmetric synapse, intracellular component",cellular_component
86457,GO:0099170,"Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.",postsynaptic modulation of chemical synaptic transmission,biological_process
86458,GO:0099171,"Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.",presynaptic modulation of chemical synaptic transmission,biological_process
86459,GO:0099172,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.",presynapse organization,biological_process
86460,GO:0099173,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.",postsynapse organization,biological_process
86461,GO:0099174,Any process that modulates the physical form of a presynapse.,regulation of presynapse organization,biological_process
86462,GO:0099175,Any process that modulates the physical form of a postsynapse.,regulation of postsynapse organization,biological_process
86463,GO:0099176,"Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.",regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex,biological_process
86464,GO:0099177,"Any process that modulates the frequency, rate or extent of trans-synaptic signaling.",regulation of trans-synaptic signaling,biological_process
86465,GO:0099178,"Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid.",regulation of retrograde trans-synaptic signaling by endocanabinoid,biological_process
86466,GO:0099179,"Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.",regulation of synaptic membrane adhesion,biological_process
86467,GO:0099180,The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.,zinc ion import into synaptic vesicle,biological_process
86468,GO:0099181,The action of a molecule that contributes to the structural integrity of a presynapse.,structural constituent of presynapse,molecular_function
86469,GO:0099182,The intermediate filament cytoskeleton that is part of a presynapse.,presynaptic intermediate filament cytoskeleton,cellular_component
86470,GO:0099183,"Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by BDNF, modulating synaptic transmission",biological_process
86471,GO:0099184,The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.,structural constituent of postsynaptic intermediate filament cytoskeleton,molecular_function
86472,GO:0099185,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.",postsynaptic intermediate filament cytoskeleton organization,biological_process
86473,GO:0099186,The action of a molecule that contributes to the structural integrity of a postsynapse.,structural constituent of postsynapse,molecular_function
86474,GO:0099187,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.",presynaptic cytoskeleton organization,biological_process
86475,GO:0099188,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.",postsynaptic cytoskeleton organization,biological_process
86476,GO:0099189,The portion of the spectrin-associated cytoskeleton contained within the postsynapse.,postsynaptic spectrin-associated cytoskeleton,cellular_component
86477,GO:0099190,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.",postsynaptic spectrin-associated cytoskeleton organization,biological_process
86478,GO:0099191,Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.,trans-synaptic signaling by BDNF,biological_process
86479,GO:0099192,A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.,cerebellar Golgi cell to granule cell synapse,cellular_component
86480,GO:0099243,"The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of synaptic membrane,cellular_component
86481,GO:0099400,"A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.",caveola neck,cellular_component
86482,GO:0099401,"The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins.",caveola bulb,cellular_component
86483,GO:0099402,"Development of a plant organ, a multi-tissue plant structure that forms a functional unit.",plant organ development,biological_process
86484,GO:0099403,"The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.","maintenance of mitotic sister chromatid cohesion, telomeric",biological_process
86485,GO:0099404,The cell cycle process in which telomeres of sister chromatids are joined during mitosis.,"mitotic sister chromatid cohesion, telomeric",biological_process
86486,GO:0099500,"Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.",vesicle fusion to plasma membrane,biological_process
86487,GO:0099501,The lipid bilayer surrounding an exocytic vesicle.,exocytic vesicle membrane,cellular_component
86488,GO:0099502,The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.,calcium-dependent activation of synaptic vesicle fusion,biological_process
86489,GO:0099503,"A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.",secretory vesicle,cellular_component
86490,GO:0099504,"A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.",synaptic vesicle cycle,biological_process
86491,GO:0099505,Any process that modulates the potential difference across a presynaptic membrane.,regulation of presynaptic membrane potential,biological_process
86492,GO:0099506,"The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.",synaptic vesicle transport along actin filament,biological_process
86493,GO:0099507,"Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.",ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential,molecular_function
86494,GO:0099508,"Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.",voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential,molecular_function
86495,GO:0099509,Any process that regulates the concentration of calcium in the presynaptic cytosol.,regulation of presynaptic cytosolic calcium ion concentration,biological_process
86496,GO:0099511,Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.,voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels,molecular_function
86497,GO:0099512,A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.,supramolecular fiber,cellular_component
86498,GO:0099513,A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.,polymeric cytoskeletal fiber,cellular_component
86499,GO:0099514,"The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.",synaptic vesicle cytoskeletal transport,biological_process
86500,GO:0099515,The transport of organelles or other particles from one location in the cell to another along actin filaments.,actin filament-based transport,biological_process
86501,GO:0099517,"The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.",synaptic vesicle transport along microtubule,biological_process
86502,GO:0099518,"The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.",vesicle cytoskeletal trafficking,biological_process
86503,GO:0099519,"The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.",dense core granule cytoskeletal transport,biological_process
86504,GO:0099522,Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.,cytosolic region,cellular_component
86505,GO:0099523,The region of the cytosol consisting of all cytosol that is part of the presynapse.,presynaptic cytosol,cellular_component
86506,GO:0099524,The region of the cytosol consisting of all cytosol that is part of the postsynapse.,postsynaptic cytosol,cellular_component
86507,GO:0099525,The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.,presynaptic dense core vesicle exocytosis,biological_process
86508,GO:0099526,"The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).",presynapse to nucleus signaling pathway,biological_process
86509,GO:0099527,"The series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).",postsynapse to nucleus signaling pathway,biological_process
86510,GO:0099528,Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled neurotransmitter receptor activity,molecular_function
86511,GO:0099530,A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.,G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential,molecular_function
86512,GO:0099532,The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.,synaptic vesicle endosomal processing,biological_process
86513,GO:0099533,Any process that increases the concentration of calcium ions in the presynaptic cytosol.,positive regulation of presynaptic cytosolic calcium concentration,biological_process
86514,GO:0099534,The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations.,calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration,molecular_function
86515,GO:0099535,The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.,synapse-associated extracellular matrix,cellular_component
86516,GO:0099536,"Cell-cell signaling to, from or within a synapse.",synaptic signaling,biological_process
86517,GO:0099537,Cell-cell signaling in either direction across the synaptic cleft.,trans-synaptic signaling,biological_process
86518,GO:0099538,"Cell-cell signaling to or from a synapse, mediated by a peptide.",synaptic signaling via neuropeptide,biological_process
86519,GO:0099539,"The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration.",neuropeptide secretion from presynapse,biological_process
86520,GO:0099540,Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.,trans-synaptic signaling by neuropeptide,biological_process
86521,GO:0099541,"Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.",trans-synaptic signaling by lipid,biological_process
86522,GO:0099542,"Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.",trans-synaptic signaling by endocannabinoid,biological_process
86523,GO:0099543,Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.,trans-synaptic signaling by soluble gas,biological_process
86524,GO:0099544,The extracellular region immediately adjacent to to a synapse.,perisynaptic space,cellular_component
86525,GO:0099545,Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.,trans-synaptic signaling by trans-synaptic complex,biological_process
86526,GO:0099546,"Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.","protein catabolic process, modulating synaptic transmission",biological_process
86527,GO:0099547,Any process that modulates synaptic transmission by regulating translation occurring at the synapse.,"regulation of translation at synapse, modulating synaptic transmission",biological_process
86528,GO:0099548,Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.,trans-synaptic signaling by nitric oxide,biological_process
86529,GO:0099549,Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.,trans-synaptic signaling by carbon monoxide,biological_process
86530,GO:0099550,"Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling, modulating synaptic transmission",biological_process
86531,GO:0099551,"Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by neuropeptide, modulating synaptic transmission",biological_process
86532,GO:0099552,"Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by lipid, modulating synaptic transmission",biological_process
86533,GO:0099553,"Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by endocannabinoid, modulating synaptic transmission",biological_process
86534,GO:0099554,"Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by soluble gas, modulating synaptic transmission",biological_process
86535,GO:0099555,"Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by nitric oxide, modulating synaptic transmission",biological_process
86536,GO:0099556,"Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by carbon monoxide, modulating synaptic transmission",biological_process
86537,GO:0099557,"Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.","trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission",biological_process
86538,GO:0099558,A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.,maintenance of synapse structure,biological_process
86539,GO:0099559,The process by which alignment between postsynaptic density and presynaptic active zone is maintained.,maintenance of alignment of postsynaptic density and presynaptic active zone,biological_process
86540,GO:0099560,The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.,synaptic membrane adhesion,biological_process
86541,GO:0099561,The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.,synaptic membrane adhesion to extracellular matrix,biological_process
86542,GO:0099562,A process which maintains the organization and the arrangement of proteins in the presynaptic density.,maintenance of postsynaptic density structure,biological_process
86543,GO:0099563,Any process that modifies the structure/morphology of a synapse.,modification of synaptic structure,biological_process
86544,GO:0099564,Any process that modulates synaptic transmission via modification of the structure of the synapse.,"modification of synaptic structure, modulating synaptic transmission",biological_process
86545,GO:0099565,The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.,"chemical synaptic transmission, postsynaptic",biological_process
86546,GO:0099566,Any process that regulates the concentration of calcium in the postsynaptic cytosol.,regulation of postsynaptic cytosolic calcium ion concentration,biological_process
86547,GO:0099567,The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.,calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration,molecular_function
86548,GO:0099568,Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.,cytoplasmic region,cellular_component
86549,GO:0099569,The portion of the cytoskeleton contained within the presynapse.,presynaptic cytoskeleton,cellular_component
86550,GO:0099571,The portion of the cytoskeleton contained within the postsynapse.,postsynaptic cytoskeleton,cellular_component
86551,GO:0099572,"A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.",postsynaptic specialization,cellular_component
86552,GO:0099573,The post-synaptic specialization of a glutamatergic excitatory synapse.,glutamatergic postsynaptic density,cellular_component
86553,GO:0099574,Any process that modulates synaptic transmission by regulating protein degradation at the synapse.,"regulation of protein catabolic process at synapse, modulating synaptic transmission",biological_process
86554,GO:0099575,Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.,"regulation of protein catabolic process at presynapse, modulating synaptic transmission",biological_process
86555,GO:0099576,Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.,"regulation of protein catabolic process at postsynapse, modulating synaptic transmission",biological_process
86556,GO:0099577,Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.,"regulation of translation at presynapse, modulating synaptic transmission",biological_process
86557,GO:0099578,Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.,"regulation of translation at postsynapse, modulating synaptic transmission",biological_process
86558,GO:0099585,"The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.",release of sequestered calcium ion into presynaptic cytosol,biological_process
86559,GO:0099586,"The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.",release of sequestered calcium ion into postsynaptic cytosol,biological_process
86560,GO:0099587,"The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.",inorganic ion import across plasma membrane,biological_process
86561,GO:0099588,Any process that increases the concentration of calcium ions in the postsynaptic cytosol.,positive regulation of postsynaptic cytosolic calcium concentration,biological_process
86562,GO:0099589,Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.,serotonin receptor activity,molecular_function
86563,GO:0099590,A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.,neurotransmitter receptor internalization,biological_process
86564,GO:0099592,The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.,endocytosed synaptic vesicle processing via endosome,biological_process
86565,GO:0099593,Fusion of an endocytosed synaptic vesicle with an endosome.,endocytosed synaptic vesicle to endosome fusion,biological_process
86566,GO:0099601,"Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.",regulation of neurotransmitter receptor activity,biological_process
86567,GO:0099602,"A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.",neurotransmitter receptor regulator activity,molecular_function
86568,GO:0099604,Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.,ligand-gated calcium channel activity,molecular_function
86569,GO:0099605,Any process that regulates the frequency of action potentials in a spike train.,regulation of action potential firing rate,biological_process
86570,GO:0099606,The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.,microtubule plus-end directed mitotic chromosome migration,biological_process
86571,GO:0099607,The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).,lateral attachment of mitotic spindle microtubules to kinetochore,biological_process
86572,GO:0099608,Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.,regulation of action potential firing pattern,biological_process
86573,GO:0099609,Binding to the side of a microtubule.,microtubule lateral binding,molecular_function
86574,GO:0099610,The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.,action potential initiation,biological_process
86575,GO:0099611,Any process that regulates the potential at which an axon potential is triggered.,regulation of action potential firing threshold,biological_process
86576,GO:0099612,A process in which a protein is transported to or maintained in a location within an axon.,protein localization to axon,biological_process
86577,GO:0099613,The process of directing proteins towards the cell-wall.,protein localization to cell wall,biological_process
86578,GO:0099614,"A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.",protein localization to spore cell wall,biological_process
86579,GO:0099615,Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = (R)-lactate + 2-oxoglutarate.,(R)-2-hydroxyglutarate-pyruvate transhydrogenase activity,molecular_function
86580,GO:0099616,"The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.",extrinsic component of matrix side of mitochondrial inner membrane,cellular_component
86581,GO:0099617,"The leaflet of a mitochondrial inner membrane that faces the matrix, including any protein embedded in, attached to, or peripherally associated with it.",matrix side of mitochondrial inner membrane,cellular_component
86582,GO:0099618,Catalysis of the reaction: UDP-alpha-D-glucuronate + NAD+ = UDP-beta-L-threo-pentopyranos-4-ulose + CO2 + NADH.,UDP-glucuronate dehydrogenase activity,molecular_function
86583,GO:0099619,"Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.",UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity,molecular_function
86584,GO:0099620,Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate.,UDP-4-amino-4-deoxy-L-arabinose:2-oxoglutarate transaminase activity,molecular_function
86585,GO:0099621,"Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.",undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity,molecular_function
86586,GO:0099622,"The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.",cardiac muscle cell membrane repolarization,biological_process
86587,GO:0099623,Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.,regulation of cardiac muscle cell membrane repolarization,biological_process
86588,GO:0099624,"The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.",atrial cardiac muscle cell membrane repolarization,biological_process
86589,GO:0099625,"The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.",ventricular cardiac muscle cell membrane repolarization,biological_process
86590,GO:0099626,Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.,voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels,molecular_function
86591,GO:0099627,"The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).",neurotransmitter receptor cycle,biological_process
86592,GO:0099628,The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.,neurotransmitter receptor diffusion trapping,biological_process
86593,GO:0099629,"A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.",postsynaptic specialization of symmetric synapse,cellular_component
86594,GO:0099630,"The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.",postsynaptic neurotransmitter receptor cycle,biological_process
86595,GO:0099631,The cytoplasmic component of the postsynaptic endocytic zone.,postsynaptic endocytic zone cytoplasmic component,cellular_component
86596,GO:0099632,A process in which protein is transported from one region of the plasma membrane to another.,protein transport within plasma membrane,biological_process
86597,GO:0099633,"A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).",protein localization to postsynaptic specialization membrane,biological_process
86598,GO:0099634,The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.,postsynaptic specialization membrane,cellular_component
86599,GO:0099635,Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.,voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels,molecular_function
86600,GO:0099636,The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.,cytoplasmic streaming,biological_process
86601,GO:0099637,The directed movement of neurotransmitter receptors.,neurotransmitter receptor transport,biological_process
86602,GO:0099638,The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.,endosome to plasma membrane protein transport,biological_process
86603,GO:0099639,The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.,"neurotransmitter receptor transport, endosome to plasma membrane",biological_process
86604,GO:0099640,The directed movement of proteins along microtubules in neuron projections.,axo-dendritic protein transport,biological_process
86605,GO:0099641,The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.,anterograde axonal protein transport,biological_process
86606,GO:0099642,The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.,retrograde axonal protein transport,biological_process
86607,GO:0099643,Any signal release from a synapse.,signal release from synapse,biological_process
86608,GO:0099644,"A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.",protein localization to presynaptic membrane,biological_process
86609,GO:0099645,"A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).",neurotransmitter receptor localization to postsynaptic specialization membrane,biological_process
86610,GO:0099646,Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.,"neurotransmitter receptor transport, plasma membrane to endosome",biological_process
86611,GO:0099703,The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.,induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration,biological_process
86612,GO:0099738,The complete extent of cell cortex that underlies some some region of the plasma membrane.,cell cortex region,cellular_component
86613,GO:0100001,Any action potential process that regulates skeletal muscle contraction.,regulation of skeletal muscle contraction by action potential,biological_process
86614,GO:0100008,Any prostaglandin biosynthetic process process that regulates fever generation.,regulation of fever generation by prostaglandin biosynthetic process,biological_process
86615,GO:0100009,Any prostaglandin secretion process that regulates fever generation.,regulation of fever generation by prostaglandin secretion,biological_process
86616,GO:0100010,Any prostaglandin biosynthetic process process that positively_regulates fever generation.,positive regulation of fever generation by prostaglandin biosynthetic process,biological_process
86617,GO:0100011,Any prostaglandin secretion process that positively_regulates fever generation.,positive regulation of fever generation by prostaglandin secretion,biological_process
86618,GO:0101002,"Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.",ficolin-1-rich granule,cellular_component
86619,GO:0101003,The lipid bilayer surrounding a ficolin-1-rich granule.,ficolin-1-rich granule membrane,cellular_component
86620,GO:0101004,The lipid bilayer surrounding the cytolytic granule.,cytolytic granule membrane,cellular_component
86621,GO:0101005,An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.,deubiquitinase activity,molecular_function
86622,GO:0101006,Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.,protein histidine phosphatase activity,molecular_function
86623,GO:0101010,The reorganization or renovation of existing pulmonary blood vessels.,pulmonary blood vessel remodeling,biological_process
86624,GO:0101013,Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,mechanosensitive voltage-gated sodium channel activity,molecular_function
86625,GO:0101014,Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.,[isocitrate dehydrogenase (NADP+)] phosphatase activity,molecular_function
86626,GO:0101016,Binding to the FMN-binding domain of a protein.,FMN-binding domain binding,molecular_function
86627,GO:0101017,"Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.",regulation of mitotic DNA replication initiation from late origin,biological_process
86628,GO:0101018,"Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.",negative regulation of mitotic DNA replication initiation from late origin,biological_process
86629,GO:0101019,"A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by ...",nucleolar exosome (RNase complex),cellular_component
86630,GO:0101020,Catalysis of the reaction: estrogen + reduced [NADPH--hemoprotein reductase] + O2 = 16-alpha-hydroxyestrogen + oxidized [NADPH--hemoprotein reductase] + H2O.,estrogen 16-alpha-hydroxylase activity,molecular_function
86631,GO:0101021,Catalysis of the reaction: estrogen + reduced [NADPH--hemoprotein reductase] + O2 = 2-hydroxyestrogen + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,estrogen 2-hydroxylase activity,molecular_function
86632,GO:0101023,"The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.",vascular endothelial cell proliferation,biological_process
86633,GO:0101024,"A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.",mitotic nuclear membrane organization,biological_process
86634,GO:0101025,"The process in which a nuclear membrane is synthesized, aggregates, and bonds together.",nuclear membrane biogenesis,biological_process
86635,GO:0101026,"A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.",mitotic nuclear membrane biogenesis,biological_process
86636,GO:0101027,The regrowth of axons of the optical nerve following their loss or damage.,optical nerve axon regeneration,biological_process
86637,GO:0101031,"A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.",protein folding chaperone complex,cellular_component
86638,GO:0102001,Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ = (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.,isoleucine N-monooxygenase (oxime forming) activity,molecular_function
86639,GO:0102002,Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ = (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.,valine N-monooxygenase (oxime forming) activity,molecular_function
86640,GO:0102003,"Catalysis of the reaction: an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O or an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-lipid (11-3)-desaturase activity,molecular_function
86641,GO:0102007,Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone = H+ + an N-acyl-L-homoserine.,acyl-L-homoserine-lactone lactonohydrolase activity,molecular_function
86642,GO:0102009,Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal = L-proline + a standard alpha amino acid.,proline dipeptidase activity,molecular_function
86643,GO:0102013,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamate(out) + ATP + H2O = L-glutamate(in) + ADP + phosphate + H+.,ATPase-coupled L-glutamate tranmembrane transporter activity,molecular_function
86644,GO:0102014,Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O = ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+.,beta-D-galactose-importing ATPase activity,molecular_function
86645,GO:0102025,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).,ABC-type thiosulfate transporter activity,molecular_function
86646,GO:0102029,Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.,D-lactate dehydrogenase (quinone) activity,molecular_function
86647,GO:0102031,"Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol = H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP.","4-acetamido-4,6-dideoxy-D-galactose transferase activity",molecular_function
86648,GO:0102033,Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid omega-hydroxylase activity,molecular_function
86649,GO:0102036,Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] = an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein].,methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity,molecular_function
86650,GO:0102039,Catalysis of the reaction: a hydroperoxide + H+ + NADH = an alcohol + H2O + NAD+.,NADH-dependent peroxiredoxin activity,molecular_function
86651,GO:0102041,"Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid.","7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity",molecular_function
86652,GO:0102042,"Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+.",dehydroquinate synthase activity,molecular_function
86653,GO:0102043,Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) = isopentenyl diphosphate(3-) + ADP(3-).,isopentenyl phosphate kinase activity,molecular_function
86654,GO:0102045,"Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor = 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.","3-chlorobenzoate-3,4-oxygenase activity",molecular_function
86655,GO:0102046,"Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor = 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.","3,4-dichlorobenzoate-4,5-oxygenase activity",molecular_function
86656,GO:0102047,Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) = H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.,indole-3-acetyl-glycine synthetase activity,molecular_function
86657,GO:0102048,Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) = H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid.,indole-3-acetyl-isoleucine synthetase activity,molecular_function
86658,GO:0102049,Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) = H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid.,indole-3-acetyl-methionine synthetase activity,molecular_function
86659,GO:0102054,Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O = H+ + maleate(2-) + pyruvate.,maleylpyruvate hydrolase activity,molecular_function
86660,GO:0102059,"Catalysis of the reaction: 2 isopentenyl diphosphate + dimethylallyl diphosphate = (2Z,6Z)-farnesyl diphosphate + 2 diphosphate.","(2Z,6Z)-farnesyl diphosphate synthase activity",molecular_function
86661,GO:0102060,"Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate = (-)-endo-alpha-bergamotene + diphosphoric acid.",endo-alpha-bergamotene synthase activity,molecular_function
86662,GO:0102061,"Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate = (+)-endo-beta-bergamotene + diphosphoric acid.",endo-beta-bergamotene synthase activity,molecular_function
86663,GO:0102062,"Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate = (+)-alpha-santalene + diphosphoric acid.",alpha-santalene synthase activity,molecular_function
86664,GO:0102064,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = gamma-curcumene + diphosphoric acid.",gamma-curcumene synthase activity,molecular_function
86665,GO:0102067,Catalysis of the reaction: phytyl diphosphate + 3 NADP+ = geranylgeranyl diphosphate + 3 NADPH + 3 H+. This enzyme also catalyzes the reduction of geranylgeranyl-chlorophyll a into phytyl-chlorophyll a.,geranylgeranyl diphosphate reductase activity,molecular_function
86666,GO:0102068,"Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ = 10-hydroxy-alpha-humulene + NADP + H2O.",alpha-humulene 10-hydroxylase activity,molecular_function
86667,GO:0102069,Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD = zerumbone + NADH + H+.,zerumbone synthase activity,molecular_function
86668,GO:0102076,Catalysis of the reaction: beta-carotene + O2 = 10'-apo-beta-carotenal + beta-ionone.,"beta,beta-carotene-9',10'-cleaving oxygenase activity",molecular_function
86669,GO:0102080,Catalysis of the reaction: phenylacetyl-CoA + glycine = H+ + phenylacetylglycine + coenzyme A.,phenylacetyl-coenzyme A:glycine N-acyltransferase activity,molecular_function
86670,GO:0102082,Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine = H+ + rebeccamycin + S-adenosyl-L-homocysteine.,demethylrebeccamycin--D-glucose O-methyltransferase activity,molecular_function
86671,GO:0102083,"Catalysis of the reaction: 7,8-dihydromonapterin = glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.","7,8-dihydromonapterin aldolase activity",molecular_function
86672,GO:0102091,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.",phosphatidylinositol-5-phosphate phosphatase activity,molecular_function
86673,GO:0102096,"Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol = dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.",decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity,molecular_function
86674,GO:0102097,"Catalysis of the reaction: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts 3-epi-6-deoxocathasterone to 6-deoxotyphasterol.",22alpha-hydroxysteroid 23-monooxygenase activity,molecular_function
86675,GO:0102098,Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.,D-galacturonate reductase activity,molecular_function
86676,GO:0102099,"Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 = 5-hydroxyisouric acid + NAD + H2O.",FAD-dependent urate hydroxylase activity,molecular_function
86677,GO:0102100,Catalysis of the reaction: arsenate + mycothiol = mycothiol-arsenate conjugate + H2O.,mycothiol-arsenate ligase activity,molecular_function
86678,GO:0102102,Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate.,homocarnosine synthase activity,molecular_function
86679,GO:0102103,Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O = bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.,demethoxycurcumin synthase activity,molecular_function
86680,GO:0102106,Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O = curcumin + 2 coenzyme A(4-) + carbon dioxide.,curcumin synthase activity,molecular_function
86681,GO:0102109,Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine = 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.,tricaffeoyl spermidine O-methyltransferase activity,molecular_function
86682,GO:0102117,Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine = gibberellin A9 methyl ester + S-adenosyl-L-homocysteine.,gibberellin A9 carboxyl methyltransferase activity,molecular_function
86683,GO:0102118,Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine = gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.,gibberellin A4 carboxyl methyltransferase activity,molecular_function
86684,GO:0102127,"Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O = 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.",8-oxoguanine deaminase activity,molecular_function
86685,GO:0102130,Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester.,malonyl-CoA methyltransferase activity,molecular_function
86686,GO:0102140,Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine.,heparan sulfate N-deacetylase activity,molecular_function
86687,GO:0102142,"Catalysis of the reaction: dermatan-[core protein] + 3'-phosphoadenylyl-sulfate = [dermatan-sulfate] containing 2-O-sulfo-alpha-L-iduronate + adenosine 3',5'-bisphosphate + H+.",dermatan 2-sulfotransferase activity,molecular_function
86688,GO:0102143,"Catalysis of the reaction: carboxynorspermidine + H2O + NADP+ = H+ + L-aspartate 4-semialdehyde + NADPH + propane-1,3-diamine. Also converts carboxyspermidine to putrescine.",carboxynorspermidine dehydrogenase activity,molecular_function
86689,GO:0102145,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (3R,6E)-nerolidol + diphosphoric acid.",(3R)-(E)-nerolidol synthase activity,molecular_function
86690,GO:0102146,Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine.,tricetin O-methytransferase activity,molecular_function
86691,GO:0102149,"Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O = (2-trans,6-trans)-farnesal + L-cysteine + H2O2.",farnesylcysteine lyase activity,molecular_function
86692,GO:0102155,Catalysis of the reaction: (S)-3-sulfonatolactate + NAD = 3-sulfonatopyruvate(2-) + NADH + H+.,S-sulfolactate dehydrogenase activity,molecular_function
86693,GO:0102157,Catalysis of the reaction: (2R)-3-sulfopropanediol + 2 NAD+ + H2O = (2R)-3-sulfolactate + 2 NADH + 3 H+.,sulfopropanediol 3-dehydrogenase activity,molecular_function
86694,GO:0102158,Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.,very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity,molecular_function
86695,GO:0102159,Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein = H+ + UDP + baicalin.,baicalein 7-O-glucuronosyltransferase activity,molecular_function
86696,GO:0102160,Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate = H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP.,cyanidin 3-O-glucoside 2-O-glucuronosyltransferase activity,molecular_function
86697,GO:0102161,"Catalysis of the reaction: copal-8-ol diphosphate = 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.",copal-8-ol diphosphate synthase activity,molecular_function
86698,GO:0102162,"Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 = all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial.","all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity",molecular_function
86699,GO:0102164,Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ = 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O.,2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity,molecular_function
86700,GO:0102165,Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol = (3Z)-hex-3-en-1-yl acetate + coenzyme A.,(Z)-3-hexen-1-ol acetyltransferase activity,molecular_function
86701,GO:0102168,Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine = 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine.,5-methyl-phenazine-1-carboxylate N-methyltransferase activity,molecular_function
86702,GO:0102169,Catalysis of the reaction: 5-methyl-phenazine-1-carboxylate + 2 H+ + NADH + O2 = CO2 + H2O + NAD+ + pyocyanin. Also converts phenazine-1-carboxylate into 1-hydroxyphenazine.,5-methylphenazine-1-carboxylate 1-monooxygenase (NADH) activity,molecular_function
86703,GO:0102170,Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 = capsidiol + 2 NADP + 2 H2O.,"5-epi-aristolochene-1,3-dihydroxylase activity",molecular_function
86704,GO:0102171,"Catalysis of the reaction: (3S,6E)-nerolidol + O2 + reduced [NADPH--hemoprotein reductase] = (3E)-4,8-dimethylnona-1,3,7-triene + but-3-en-2-one + H+ + 2 H2O + oxidized [NADPH--hemoprotein reductase].",DMNT synthase activity,molecular_function
86705,GO:0102172,"Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ = 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.","4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity",molecular_function
86706,GO:0102175,Catalysis of the reaction: a 3-beta-hydroxysteroid-4-alpha-carboxylate + NAD+ = a 3-oxosteroid + CO2 + NADH.,3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity,molecular_function
86707,GO:0102177,"Catalysis of the reaction: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H+ = 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O.",4alpha-monomethylsterol monooxygenase activity,molecular_function
86708,GO:0102180,"Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ = 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O.","4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity",molecular_function
86709,GO:0102193,Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine = ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine.,protein-ribulosamine 3-kinase activity,molecular_function
86710,GO:0102194,Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine = ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine.,protein-fructosamine 3-kinase activity,molecular_function
86711,GO:0102195,Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP = UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+.,UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity,molecular_function
86712,GO:0102196,Catalysis of the reaction: cortisol + NADP+ = cortisone + NADPH + H+.,cortisol dehydrogenase (NADP+) activity,molecular_function
86713,GO:0102197,Catalysis of the reaction: but-3-enoate + H2O = allyl alcohol + formate.,vinylacetate caboxylester hydrolase activity,molecular_function
86714,GO:0102198,Catalysis of the reaction: L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+.,L-idonate 5-dehydrogenase (NAD+) activity,molecular_function
86715,GO:0102199,Catalysis of the reaction: H2O + NAD(P)+ + nitrous oxide = H+ + NAD(P)H + 2 nitric oxide.,nitric oxide reductase [NAD(P)H] activity,molecular_function
86716,GO:0102201,"Catalysis of the reaction: (2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate.",(+)-2-epi-prezizaene synthase activity,molecular_function
86717,GO:0102208,"Catalysis of the reaction: a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H+ + S-adenosyl-L-homocysteine.",2-polyprenyl-6-hydroxyphenol methylase activity,molecular_function
86718,GO:0102209,"Catalysis of the reaction: (-)-trans-permethrin + H2O = H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate.",trans-permethrin hydrolase activity,molecular_function
86719,GO:0102210,"Catalysis of the reaction: H2O + a rhamnogalacturonan type I = [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide].",rhamnogalacturonan endolyase activity,molecular_function
86720,GO:0102211,"Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose.",unsaturated rhamnogalacturonyl hydrolase activity,molecular_function
86721,GO:0102212,Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate.,unsaturated chondroitin disaccharide hydrolase activity,molecular_function
86722,GO:0102215,Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine = methyl thiocyanate + S-adenosyl-L-homocysteine.,thiocyanate methyltransferase activity,molecular_function
86723,GO:0102220,Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin.,"hydrogenase activity (NAD+, ferredoxin)",molecular_function
86724,GO:0102223,"Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD = 4,4'-diapolycopene + 4 FADH2. This reaction consists of four successive dehydrogenations that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene, 4,4'-diapo-zeta-carotene and 4,4'-diapolycopene as intermediates, and 4,4'-diapolycopene as the end product.","4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) activity",molecular_function
86725,GO:0102224,"Catalysis of the reaction: GDP-N,N'-diacetylbacillosamine + H2O = 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.","GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity",molecular_function
86726,GO:0102232,Catalysis of the reaction: propanal + NADP+ = acrolein + NADPH + H+.,acrolein reductase activity,molecular_function
86727,GO:0102236,Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ = hexan-3-one + NADP.,trans-4-hexen-3-one reductase activity,molecular_function
86728,GO:0102240,Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate = H+ + UDP + soyasaponin III.,soyasapogenol B glucuronide galactosyltransferase activity,molecular_function
86729,GO:0102241,Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III = H+ + UDP + soyasaponin I.,soyasaponin III rhamnosyltransferase activity,molecular_function
86730,GO:0102244,Catalysis of the reaction: 3-aminopropanal + H2O + NAD+ = beta-alanine + 2 H+ + NADH.,3-aminopropanal dehydrogenase (NAD+) activity,molecular_function
86731,GO:0102245,"Catalysis of the reaction: lupan-3beta,20-diol = (S)-2,3-epoxysqualene + H2O.","lupan-3beta,20-diol synthase activity",molecular_function
86732,GO:0102246,Catalysis of the reaction: aminodeoxyfutalosinate + H2O = dehypoxanthine futalosine + adenine.,6-amino-6-deoxyfutalosine hydrolase activity,molecular_function
86733,GO:0102251,"Catalysis of the reaction: 10'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial.",all-trans-beta-apo-10'-carotenal cleavage oxygenase activity,molecular_function
86734,GO:0102252,"Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains.","cellulose 1,4-beta-cellobiosidase activity (reducing end)",molecular_function
86735,GO:0102261,Catalysis of the reaction: NADP+ + reduced coenzyme F420-(gamma-L-Glu)(n) = 2 H+ + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n).,8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity,molecular_function
86736,GO:0102262,"Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) = H+ + a uracil16 in tRNA + NAD(P)H.",tRNA-dihydrouridine16 synthase activity,molecular_function
86737,GO:0102263,"Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) = H+ + a uracil17 in tRNA + NAD(P)H.",tRNA-dihydrouridine17 synthase activity,molecular_function
86738,GO:0102264,"Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) = H+ + a uracil20 in tRNA + NAD(P)H.",tRNA-dihydrouridine20 synthase activity,molecular_function
86739,GO:0102265,"Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) = H+ + a uracil47 in tRNA + NAD(P)H.",tRNA-dihydrouridine47 synthase activity,molecular_function
86740,GO:0102266,"Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) = H+ + a uracil20a in tRNA + NAD(P)H.",tRNA-dihydrouridine20a synthase activity,molecular_function
86741,GO:0102267,"Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) = H+ + a uracil20b in tRNA + NAD(P)H.",tRNA-dihydrouridine20b synthase activity,molecular_function
86742,GO:0102274,Catalysis of the reaction: an S-substituted glutathione + H2O = glycine + S-substituted gamma-glutamyl-L-cysteine. Patricipates in glutathione-mediated detoxification.,glutathione S-conjugate carboxypeptidase activity,molecular_function
86743,GO:0102276,Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ = ethene + 3 carbon dioxide + H2O.,2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity,molecular_function
86744,GO:0102277,Catalysis of the reaction: beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine + H2O = D-glucosamine + N-acetyl-D-glucosamine.,2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity,molecular_function
86745,GO:0102280,Catalysis of the reaction: choline + NADP+ = betaine aldehyde + NADPH + H+.,choline monooxygenase (NADP+) activity,molecular_function
86746,GO:0102285,Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP.,1-deoxy-11-oxopentalenate oxygenase activity,molecular_function
86747,GO:0102289,Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ = 11-oxo-beta-amyrin + 3 H2O + 2 NADP.,beta-amyrin 11-oxidase activity,molecular_function
86748,GO:0102294,Catalysis of the reaction: cholesterol + NAD+ = cholest-5-en-3-one + NADH + H+.,cholesterol dehydrogenase (NAD+) activity,molecular_function
86749,GO:0102296,"Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O = 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.","4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity",molecular_function
86750,GO:0102299,"Catalysis of the reaction: (9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate. Also converts linoleate to (9R,10E,12Z)-9- hydroperoxyoctadeca-10,12-dienoate.",linolenate 9R-lipoxygenase activity,molecular_function
86751,GO:0102302,Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI = S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+.,mycinamicin VI 2''-O-methyltransferase activity,molecular_function
86752,GO:0102303,Catalysis of the reaction: 2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene + 2 H+.,"resveratrol 3,5-O-dimethyltransferase activity",molecular_function
86753,GO:0102304,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = 7-epi-sesquithujene + diphosphoric acid.",sesquithujene synthase activity,molecular_function
86754,GO:0102305,"Catalysis of the reaction: geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate.","(13E)-labda-7,13-dien-15-ol synthase activity",molecular_function
86755,GO:0102307,Catalysis of the reaction: erythromycin C + S-adenosyl-L-methionine = erythromycin A + H+ + S-adenosyl-L-homocysteine. Also converts erythromycin D into erythromycin B.,erythromycin 3''-o-methyltransferase activity,molecular_function
86756,GO:0102311,Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP = (6E)-8-oxogeranial + 2 NADPH + 2 H+.,8-hydroxygeraniol dehydrogenase activity,molecular_function
86757,GO:0102312,"Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 = 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide.",4-coumaroyl 2'-hydroxylase activity,molecular_function
86758,GO:0102313,"Catalysis of the reaction: geranyl diphosphate(3-) + H2O = 1,8-cineole + diphosphoric acid.","1,8-cineole synthase activity",molecular_function
86759,GO:0102317,Catalysis of the reaction: 4-(methylamino)butanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2.,4-methylaminobutyrate oxidase (demethylating) activity,molecular_function
86760,GO:0102318,Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose = 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+.,2-deoxystreptamine glucosyltransferase activity,molecular_function
86761,GO:0102319,Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine = H+ + 2'-N-acetylparomamine(2+) + UDP(3-).,2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity,molecular_function
86762,GO:0102320,"Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 = 2-exo-hydroxy-1,8-cineole + NADP + H2O.","1,8-cineole 2-exo-monooxygenase activity",molecular_function
86763,GO:0102322,Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD.,2-propylphenol monooxygenase activity,molecular_function
86764,GO:0102323,Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD.,2-isopropylphenol monooxygenase activity,molecular_function
86765,GO:0102325,"Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ = 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O.","2,2',3-trihydroxybiphenyl monooxygenase activity",molecular_function
86766,GO:0102334,"Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine = N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP.","N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity",molecular_function
86767,GO:0102335,"Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine = N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.","N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity",molecular_function
86768,GO:0102354,Catalysis of the reaction: 11-cis-retinol + NADP+ = 11-cis-retinal + NADPH + H+.,11-cis-retinol dehydrogenase (NADP+) activity,molecular_function
86769,GO:0102355,Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.,2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity,molecular_function
86770,GO:0102357,"Catalysis of the reaction: mithramycin DK + NADPH + H+ = iso-mithramycin + NADP+. Note that  iso-mithramycin (iso-MTM) is a C2-epimer of mithramycin.  This intermediate appears to be biologically important because it is non-toxic, then exported out of the cell and finally spontaneously epimerized into the toxic mithramycin. This could represent a self-resistance mechanism against MTM toxicity.",mithramycin dehydrogenase (NADPH) activity,molecular_function
86771,GO:0102358,"Catalysis of the reaction: 7,8-dihydroxycoumarin + S-adenosyl-L-methionine = 7-hydroxy-8-methoxycoumarin + H+ + S-adenosyl-L-homocysteine.",daphnetin-8-O-methyltransferase activity,molecular_function
86772,GO:0102365,"Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O. Also converts 7beta-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin.",taxoid 2alpha-hydroxylase activity,molecular_function
86773,GO:0102373,Catalysis of the reaction: beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4 H+ + 4 H2O + oleanolate + 3 oxidized [NADPH--hemoprotein reductase].,beta-amyrin 28-monooxygenase activity,molecular_function
86774,GO:0102375,Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ = glycyrrhetinic acid + 3 NADP + 4 H2O.,11-oxo-beta-amyrin 30-oxidase activity,molecular_function
86775,GO:0102377,Catalysis of the reaction: steviol + UDP-alpha-D-glucose = H+ + steviolmonoside + UDP.,steviol 13-O glucosyltransferase activity,molecular_function
86776,GO:0102378,Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP.,steviolmonoside glucosyltransferase activity,molecular_function
86777,GO:0102379,Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP.,steviolbioside glucosyltransferase activity (stevioside forming),molecular_function
86778,GO:0102380,Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = H+ + rebaudioside B + UDP.,steviolbioside glucosyltransferase activity (rebaudioside B forming),molecular_function
86779,GO:0102381,Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = H+ + rebaudioside A + UDP.,stevioside glucosyltransferase activity (rebaudioside A forming),molecular_function
86780,GO:0102382,Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose = rebaudioside A + UDP.,rebaudioside B glucosyltransferase activity,molecular_function
86781,GO:0102386,Catalysis of the reaction: 2-phenylacetaldehyde + NADPH + H+ = 2-phenylethanol + NADP+.,phenylacetaldehyde reductase activity,molecular_function
86782,GO:0102388,"Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O = 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+.","UDP-N,N'-diacetylbacillosamine 2-epimerase activity",molecular_function
86783,GO:0102389,"Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol.",polyprenol reductase activity,molecular_function
86784,GO:0102390,Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O = mycophenolate + H+ + D-glucopyranuronate.,mycophenolic acid acyl-glucuronide esterase activity,molecular_function
86785,GO:0102391,Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA.,decanoate-CoA ligase activity,molecular_function
86786,GO:0102394,Catalysis of the reaction: L-isoleucine + 2-oxoglutarate + O2 = (4S)-4-hydroxy-L-isoleucine + succinate + CO2.,L-isoleucine 4-hydroxylase activity,molecular_function
86787,GO:0102395,Catalysis of the reaction: 9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone.,"9-cis-beta-carotene 9',10'-cleavage oxygenase activity",molecular_function
86788,GO:0102396,"Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 = carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal.",9-cis-10'-apo-beta-carotenal cleavage oxygenase activity,molecular_function
86789,GO:0102405,Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ = (+)-dihydromyricetin + NADP(3-) + H2O.,(+)-taxifolin 5'-hydroxylase activity,molecular_function
86790,GO:0102406,Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate = coenzyme A + 16-sinapoyloxypalmitate.,omega-hydroxypalmitate O-sinapoyl transferase activity,molecular_function
86791,GO:0102412,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = valerena-4,7(11)-diene + diphosphoric acid.","valerena-4,7(11)-diene synthase activity",molecular_function
86792,GO:0102413,Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O = 6-O-methyl-N-deacetylisoipecoside aglycon + D-glucose.,6-O-methyl-deacetylisoipecoside beta-glucosidase activity,molecular_function
86793,GO:0102423,Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose = (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+.,(+)-sesaminol 2-O-glucosyltransferase activity,molecular_function
86794,GO:0102431,"Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid) and add a fourth double bond (a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid).",acyl-lipid omega-(9-4) desaturase activity,molecular_function
86795,GO:0102432,Catalysis of the reaction: quercetin + S-adenosyl-L-methionine = H+ + rhamnetin + S-adenosyl-L-homocysteine.,quercetin 7-O-methyltransferase activity,molecular_function
86796,GO:0102434,Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.,pterin-4alpha-carbinolamine dehydratase activity,molecular_function
86797,GO:0102435,Catalysis of the reaction: myricetin + S-adenosyl-L-methionine = 7-O-methylmyricetin + H+ + S-adenosyl-L-homocysteine.,myricetin 7-O-methyltransferase activity,molecular_function
86798,GO:0102439,"Catalysis of the reaction: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine = 7,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine.","3',4',5'-trimethylmyricetin 7-O-methyltransferase activity",molecular_function
86799,GO:0102440,"Catalysis of the reaction: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine = 3,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine.","3',4',5'-trimethylmyricetin 3-O-methyltransferase activity",molecular_function
86800,GO:0102441,"Catalysis of the reaction: S-adenosyl-L-methionine + syringetin = 7,3',5'-O-trimethylmyricetin + H+ + S-adenosyl-L-homocysteine.",syringetin 7-O-methyltransferase activity,molecular_function
86801,GO:0102442,"Catalysis of the reaction: S-adenosyl-L-methionine + syringetin = 3,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine.",syringetin 3-O-methyltransferase activity,molecular_function
86802,GO:0102443,Catalysis of the reaction: a (2S)-2-hydroxycarboxylate + NAD+ = a 2-oxocarboxylate + NADH + H+.,L-2-hydroxycarboxylate dehydrogenase (NAD+) activity,molecular_function
86803,GO:0102444,"Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine = 3,3'-O-dimethylquercetin + H+ + S-adenosyl-L-homocysteine.",isorhamnetin 3-O-methyltransferase activity,molecular_function
86804,GO:0102445,"Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine = 3,3'-O-dimethylquercetin + H+ + S-adenosyl-L-homocysteine.",3-methylquercetin 3'-O-methyltransferase activity,molecular_function
86805,GO:0102446,"Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,7-dimethoxyflavone + H+ + S-adenosyl-L-homocysteine.",rhamnetin 3-O-methyltransferase activity,molecular_function
86806,GO:0102447,Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = H+ + rhamnacene + S-adenosyl-L-homocysteine.,rhamnetin 3'-O-methyltransferase activity,molecular_function
86807,GO:0102448,"Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = 7,4'-O-dimethylquercetin + H+ + S-adenosyl-L-homocysteine.",rhamnetin 4'-O-methyltransferase activity,molecular_function
86808,GO:0102449,Catalysis of the reaction: kaempferol + S-adenosyl-L-methionine = 3-O-methylkaempferol + H+ + S-adenosyl-L-homocysteine.,kaempferol 3-O-methyltransferase activity,molecular_function
86809,GO:0102450,"Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine = 7,4'-O-dimethylkaempferol + H+ + S-adenosyl-L-homocysteine.",kaempferide 7-O-methyltransferase activity,molecular_function
86810,GO:0102451,"Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine = 3,4'-O-dimethylkaempferol + H+ + S-adenosyl-L-homocysteine.",kaempferide 3-O-methyltransferase activity,molecular_function
86811,GO:0102452,Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ = 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.,bisdemethoxycurcumin synthase activity,molecular_function
86812,GO:0102453,Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside].,anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity,molecular_function
86813,GO:0102454,Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP.,cyanidin 3-O-galactosyltransferase activity,molecular_function
86814,GO:0102455,Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside.,anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity,molecular_function
86815,GO:0102457,"Catalysis of the reaction: 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + cyanidin 3-O-beta-D-glucoside = cyanidin 3,7-di-O-beta-D-glucoside + vanillate.",cyanidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose) activity,molecular_function
86816,GO:0102464,Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ = caloxanthin + H2O + NAD.,zeaxanthin 2-beta-hydroxylase activity,molecular_function
86817,GO:0102467,Catalysis of the reaction: scutellarein + UDP-alpha-D-glucuronate = scutellarin + UDP.,scutellarein 7-O-glucuronosyltransferase activity,molecular_function
86818,GO:0102468,Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin = UDP + wogonin 7-O-beta-D-glucuronate + H+.,wogonin 7-O-glucuronosyltransferase activity,molecular_function
86819,GO:0102469,Catalysis of the reaction:(2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].,naringenin 2-hydroxylase activity,molecular_function
86820,GO:0102478,Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose.,beta-L-arabinofuranosidase activity,molecular_function
86821,GO:0102481,"Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H+.","3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity",molecular_function
86822,GO:0102482,Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.,5-deoxy-D-glucuronate isomerase activity,molecular_function
86823,GO:0102497,"Catalysis of the reaction: scyllo-inositol + NADP = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+.",scyllo-inositol dehydrogenase (NADP+) activity,molecular_function
86824,GO:0102501,Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate.,D-fructuronate reductase activity,molecular_function
86825,GO:0102506,Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+.,cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose) activity,molecular_function
86826,GO:0102517,Catalysis of the reaction: (9Z)-octadecenoate + AH2 + O2 = (12R)-hydroxy-(9Z)-octadecenoate + acceptor + H2O.,oleate 12-hydroxylase activity,molecular_function
86827,GO:0102521,Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe.,tRNA-4-demethylwyosine synthase activity,molecular_function
86828,GO:0102522,Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe = 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe.,tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity,molecular_function
86829,GO:0102523,Catalysis of the reaction: (S)-2-chloropropanoate + NADP = 2-chloroacrylate + NADPH + H+.,2-chloroacrylate reductase activity,molecular_function
86830,GO:0102524,Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe.,tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity,molecular_function
86831,GO:0102525,Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide.,"2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity",molecular_function
86832,GO:0102526,Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid = S-adenosyl-L-homocysteine + novobiocic acid + H+.,8-demethylnovobiocic acid C8-methyltransferase activity,molecular_function
86833,GO:0102527,"Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) = H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid.",8-demethylnovobiocate synthase activity,molecular_function
86834,GO:0102529,Catalysis of the reaction: apigenin + S-adenosyl-L-methionine = genkwanin + H+ + S-adenosyl-L-homocysteine.,apigenin 7-O-methyltransferase activity,molecular_function
86835,GO:0102530,Catalysis of the reaction: aclacinomycin T(1+) + H2O = 15-demethylaclacinomycin T + methanol + H+.,aclacinomycin T methylesterase activity,molecular_function
86836,GO:0102531,Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = phosphate + an ecdysteroid. Also has activity towards other ecdysteriod phosphates including 20-hydroxyecdysone 22-phosphate (20E22P) and 2-deoxyecdysone 22-phosphate (2dE22P).,ecdysteroid-phosphate phosphatase activity,molecular_function
86837,GO:0102532,Catalysis of the reaction: genkwanin + O2 + reduced [NADPH--hemoprotein reductase] = H2O + oxidized [NADPH--hemoprotein reductase] + scutellarein 7-methyl ether.,genkwanin 6-hydroxylase activity,molecular_function
86838,GO:0102533,"Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine = apigenin 4',7-dimethyl ether + S-adenosyl-L-homocysteine.",genkwanin 4'-O-methyltransferase activity,molecular_function
86839,GO:0102534,"Catalysis of the reaction: apigenin 4',7-dimethyl ether + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + ladanein + oxidized [NADPH--hemoprotein reductase].","apigenin-7,4'-dimethyl ether 6-hydroxylase activity",molecular_function
86840,GO:0102535,Catalysis of the reaction: ladanein + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + salvigenin.,ladanein 6-O-methyltransferase activity,molecular_function
86841,GO:0102536,Catalysis of the reaction: (2S)-sakuranetin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-7-methylcarthamidin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].,sakuranetin 6-hydroxylase activity,molecular_function
86842,GO:0102538,"Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.",UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity,molecular_function
86843,GO:0102539,"Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.",UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity,molecular_function
86844,GO:0102545,A glycerophospholipase activity that cleaves both fatty acisd attached to the sn-1 and the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine and phosphatidylethanolamine.,B-type glycerophospholipase activity,molecular_function
86845,GO:0102546,Catalysis of the reaction: (2R)-2-O-(alpha-D-mannosyl)-glycerate + H2O = (R)-glycerate + D-mannose.,mannosylglycerate hydrolase activity,molecular_function
86846,GO:0102547,Catalysis of the reaction: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O = (R)-glycerate + D-glucose.,glucosylglycerate hydrolase activity,molecular_function
86847,GO:0102550,"Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+.","2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity",molecular_function
86848,GO:0102556,Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 = (20S)-protopanaxadiol + NADP + H2O.,dammarenediol 12-hydroxylase activity,molecular_function
86849,GO:0102557,Catalysis of the reaction: (20S)-protopanaxadiol + O2 + reduced [NADPH--hemoprotein reductase] = (20S)-protopanaxatriol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,protopanaxadiol 6-hydroxylase activity,molecular_function
86850,GO:0102559,Catalysis of the reaction: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+.,peptide chain release factor N(5)-glutamine methyltransferase activity,molecular_function
86851,GO:0102561,"Catalysis of the reaction: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = D-ribose 2,5-bisphosphate + H+.","phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase activity",molecular_function
86852,GO:0102571,Catalysis of the reaction: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl/L-threonyl-[protein] + H2O = L-seryl//L-threonyl-[protein] + N-acetyl-D-glucosamine.,[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity,molecular_function
86853,GO:0102572,Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+.,N-glutamylanilide hydrolase activity,molecular_function
86854,GO:0102573,Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O = aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+.,aminodeoxyfutalosine synthase activity,molecular_function
86855,GO:0102580,Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose = cyanidin 3-O-beta-D-sambubioside + UDP.,cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity,molecular_function
86856,GO:0102585,Catalysis of the reaction: anthocyanin A3 + malonyl-CoA = anthocyanin A5 + CoA.,cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity,molecular_function
86857,GO:0102596,"Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 = ent-sandaracopimaradien-3beta-ol + NADP + H2O.",cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity,molecular_function
86858,GO:0102597,Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 = oryzalexin E + NADP + H2O.,3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity,molecular_function
86859,GO:0102598,Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 = oryzalexin D + NADP + H2O.,3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity,molecular_function
86860,GO:0102601,Catalysis of the reaction: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase].,beta-amyrin 16beta-monooxygenase activity,molecular_function
86861,GO:0102610,Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose = (+)-secoisolariciresinol monoglucoside + UDP + H+.,(+)-secoisolariciresinol glucosyltransferase activity,molecular_function
86862,GO:0102611,Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose = (+)-secoisolariciresinol diglucoside + UDP + H+.,(+)-secoisolariciresinol monoglucoside glucosyltransferase activity,molecular_function
86863,GO:0102612,"Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ = 6beta-hydroxy-syn-pimaradiene + NADP + H2O.",syn-pimaradiene 6beta-hydroxylase activity,molecular_function
86864,GO:0102613,"Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ = 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.",trimethyluric acid monooxygenase activity,molecular_function
86865,GO:0102614,"Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].",germacrene A acid 8beta-hydroxylase activity,molecular_function
86866,GO:0102623,Catalysis of the reaction: S-adenosyl-L-methionine + scutellarein 7-methyl ether = cirsimaritin + H+ + S-adenosyl-L-homocysteine.,scutellarein 7-methyl ether 6-O-methyltransferase activity,molecular_function
86867,GO:0102624,Catalysis of the reaction: S-adenosyl-L-methionine + scutellarein 7-methyl ether = H+ + ladanein + S-adenosyl-L-homocysteine.,scutellarein 7-methyl ether 4'-O-methyltransferase activity,molecular_function
86868,GO:0102625,Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + salvigenin.,cirsimaritin 4'-O-methyltransferase activity,molecular_function
86869,GO:0102626,Catalysis of the reaction: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + oxidized [NADPH--hemoprotein reductase] + parthenolide.,parthenolide synthase activity,molecular_function
86870,GO:0102627,Catalysis of the reaction: O2 + parthenolide + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxyparthenolide + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,parthenolide 3beta-hydroxylase activity,molecular_function
86871,GO:0102628,"Catalysis of the reaction: (+)-costunolide (12,6alpha) + reduced [NADPH-hemoprotein reductase] + dioxygen = 3beta-hydroxycostunolide + oxidized [NADPH-hemoprotein reductase] + H2O.",costunolide 3beta-hydroxylase activity,molecular_function
86872,GO:0102632,Catalysis of the reaction: (S)-scoulerine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-nandinine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+.,(S)-nandinine synthase activity,molecular_function
86873,GO:0102634,"Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 = flaviolin-2-olate + H2O + H+.","1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity",molecular_function
86874,GO:0102635,"Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD.",11-deoxycorticosterone reductase activity,molecular_function
86875,GO:0102645,Catalysis of the reaction: 17(E)-cheilanthenediol = all-trans-geranylfarnesol + H2O.,17(E)-cheilanthenediol synthase activity,molecular_function
86876,GO:0102646,Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol = all-trans-geranylfarnesol + H2O.,14betaH-scalarane-17alpha-19-diol synthase activity,molecular_function
86877,GO:0102654,Catalysis of the reaction: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. The this activity introduces an unusual trans double bond at carbon 3 of a palmitoyl group attached to the sn-2 position of glycerolipids.,palmitoyl-[glycerolipid] 3-(E)-desaturase activity,molecular_function
86878,GO:0102670,"Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.","2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity",molecular_function
86879,GO:0102671,Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine = H+ + (+)-pisatin + S-adenosyl-L-homocysteine.,6a-hydroxymaackiain-3-O-methyltransferase activity,molecular_function
86880,GO:0102672,"Catalysis of the reaction: a 1,2-saturated fatty acid + O2 = a (2R)-2-hydroperoxy fatty acid.",fatty acid alpha-dioxygenase activity,molecular_function
86881,GO:0102673,Catalysis of the reaction: a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH.,fatty aldehyde dehydrogenase (NAD+) activity,molecular_function
86882,GO:0102679,"Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH = (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP.",(5alpha)-campestan-3-one hydroxylase activity,molecular_function
86883,GO:0102682,Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate.,cytokinin riboside 5'-monophosphate phosphoribohydrolase activity,molecular_function
86884,GO:0102684,Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ = (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.,L-phenylalanine N-monooxygenase activity,molecular_function
86885,GO:0102698,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-5-epi-aristolochene + diphosphoric acid.",5-epi-aristolochene synthase activity,molecular_function
86886,GO:0102700,Catalysis of the reaction: geranyl diphosphate(3-) = alpha-thujene + diphosphoric acid.,alpha-thujene synthase activity,molecular_function
86887,GO:0102701,Catalysis of the reaction: geranyl diphosphate(3-) = tricyclene + diphosphoric acid.,tricyclene synthase activity,molecular_function
86888,GO:0102702,Catalysis of the reaction: geranyl diphosphate = (+)-2-carene + diphosphoric acid.,2-carene synthase activity,molecular_function
86889,GO:0102703,Catalysis of the reaction: geranyl diphosphate = (-)-camphene + diphosphoric acid.,camphene synthase activity,molecular_function
86890,GO:0102704,"Catalysis of the reaction: an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H+.","GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity",molecular_function
86891,GO:0102705,Catalysis of the reaction: H+ + L-serine = ethanolaminium(1+) + carbon dioxide.,serine decarboxylase activity,molecular_function
86892,GO:0102710,Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+.,D-inositol-3-phosphate glycosyltransferase activity,molecular_function
86893,GO:0102717,Catalysis of the reaction: DIBOA beta-D-glucoside + 2-oxoglutarate + O2 = TRIBOA beta-D-glucoside + succinate + CO2.,DIBOA-glucoside oxygenase activity,molecular_function
86894,GO:0102718,Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine = (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+.,TRIBOA-glucoside methyltransferase activity,molecular_function
86895,GO:0102720,Catalysis of the reaction: acetyl-CoA + benzyl alcohol = benzyl acetate + CoA. Also converts (E)-cinnamyl alcohol into (E)-cinnamyl acetate.,acetyl-coenzyme A:acetyl alcohol acetyltransferase activity,molecular_function
86896,GO:0102721,Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone.,ubiquinol:oxygen oxidoreductase activity,molecular_function
86897,GO:0102726,Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose.,DIMBOA glucoside beta-D-glucosidase activity,molecular_function
86898,GO:0102731,"Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP + H+.","inositol-1,3,4,6-tetrakisphosphate 2-kinase activity",molecular_function
86899,GO:0102732,"Catalysis of the reaction: 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H+.","inositol-1,2,3,4,6-pentakisphosphate 5-kinase activity",molecular_function
86900,GO:0102733,Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor.,typhasterol C-23 hydroxylase activity,molecular_function
86901,GO:0102734,"Catalysis of the reaction: castasterone + O2 + reduced [NADPH--hemoprotein reductase] = brassinolide + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Broad specificity for several brassinosteroids, including castasterone, teasterone, and typhasterol.",brassinolide synthase activity,molecular_function
86902,GO:0102735,"Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.",trihydroxybenzophenone synthase activity,molecular_function
86903,GO:0102741,"Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine = H+ + caffeine + S-adenosyl-L-homocysteine. Also converts theobromine to caffeine and 7-methylxanthine to theobromine.",caffeine synthase activity,molecular_function
86904,GO:0102757,Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.,NADPH phosphatase activity,molecular_function
86905,GO:0102758,"Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + NADP+ = a very-long-chain (2E)-enoyl-CoA + H+ + NADPH. This reaction is the fourth (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.",very-long-chain enoyl-CoA reductase activity,molecular_function
86906,GO:0102761,Catalysis of the reaction: (S)-eriodictyol + S-adenosyl-L-methionine = (S)-homoeriodictyol + H+ + S-adenosyl-L-homocysteine.,eriodictyol 3'-O-methyltransferase activity,molecular_function
86907,GO:0102763,Catalysis of the reaction: a ribonucleoside 5'-triphosphate + phytyl phosphate = a ribonucleoside 5'-diphosphate + phytyl diphosphate.,phytyl-P kinase activity,molecular_function
86908,GO:0102765,Catalysis of the reaction: UDP-alpha-D-glucuronate + H+ = UDP-alpha-D-apiose + CO2.,UDP-D-apiose synthase activity,molecular_function
86909,GO:0102766,Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine = sakuranetin + S-adenosyl-L-homocysteine + H+.,naringenin 7-O-methyltransferase activity,molecular_function
86910,GO:0102767,Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.,flavanone 4'-O-methyltransferase activity,molecular_function
86911,GO:0102770,"Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.",inositol phosphorylceramide synthase activity,molecular_function
86912,GO:0102771,"Catalysis of the reaction: an N-(1,2-saturated acyl)sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-[(2'R)-hydroxyacyl]sphinganine + 2 Fe(III)-[cytochrome b5] + H2O.",dihydroceramide fatty acyl 2-hydroxylase activity,molecular_function
86913,GO:0102772,Catalysis of the reaction: a dihydroceramide + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O.,sphingolipid C4-monooxygenase activity,molecular_function
86914,GO:0102778,Catalysis of the reaction: cannabigerolate + O2 = delta(9)-tetrahydrocannabinolic acid +  H2O2.,delta9-tetrahydrocannabinolate synthase activity,molecular_function
86915,GO:0102779,Catalysis of the reaction: cannabigerolate + O2 = cannabidiolate + H2O2.,cannabidiolate synthase activity,molecular_function
86916,GO:0102785,"Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.",violaxanthin oxygenase activity,molecular_function
86917,GO:0102793,Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B = H+ + UDP + soyasapogenol B 3-O-beta-glucuronate.,soyasapogenol B glucuronosyltransferase activity,molecular_function
86918,GO:0102801,Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A.,anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity,molecular_function
86919,GO:0102802,Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 = neopinone + formaldehyde + succinate + carbon dioxide.,thebaine 6-O-demethylase activity,molecular_function
86920,GO:0102805,Catalysis of the reaction: codeine + 2-oxoglutarate + O2 = morphine + formaldehyde + succinate + CO2.,codeine O-demethylase activity,molecular_function
86921,GO:0102810,Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+.,glutarate-semialdehyde dehydrogenase (NADP+) activity,molecular_function
86922,GO:0102811,Catalysis of the reaction: geraniol + O2 + NADPH + H+ = (6E)-8-hydroxygeraniol + NADP + H2O.,geraniol 10-hydroxylase activity,molecular_function
86923,GO:0102816,Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside = H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.,UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity,molecular_function
86924,GO:0102822,Catalysis of the reaction: a 3'-hydroxyflavone + S-adenosyl-L-methionine = a 3'-methoxyflavone + H+ + S-adenosyl-L-homocysteine.,flavone 3'-O-methyltransferase activity,molecular_function
86925,GO:0102830,Catalysis of the reaction: 2 stachyose = verbascose + raffinose.,verbascose synthase activity,molecular_function
86926,GO:0102831,Catalysis of the reaction: 2 raffinose = stachyose + sucrose.,stachyose synthase activity,molecular_function
86927,GO:0102832,Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol = ajugose + myo-inositol.,verbascose galactinol:ajugose galactosyltransferase activity,molecular_function
86928,GO:0102843,Catalysis of the reaction: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin].,palmitoyl-[glycerolipid] 7-desaturase activity,molecular_function
86929,GO:0102850,"Catalysis of the reaction: a (9Z)-octadecenoyl-containing glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin].",acyl-lipid (n+3)-(Z)-desaturase (ferredoxin) activity,molecular_function
86930,GO:0102859,"Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-lipid omega-3 desaturase (cytochrome b5) activity,molecular_function
86931,GO:0102865,"Catalysis of the reaction: a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.",delta6-acyl-lipid desaturase activity,molecular_function
86932,GO:0102866,"Catalysis of the reaction: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O. Also converts an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid into a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-containing glycerolipid.",acyl-lipid (8-3)-desaturase activity,molecular_function
86933,GO:0102876,Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 = psoralen + NADP + acetone + 2 H2O.,psoralen synthase (NADPH) activity,molecular_function
86934,GO:0102877,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-copaene + diphosphoric acid.",alpha-copaene synthase activity,molecular_function
86935,GO:0102878,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (+)-alpha-barbatene + diphosphate.",(+)-alpha-barbatene synthase activity,molecular_function
86936,GO:0102879,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-thujopsene + diphosphoric acid.",(+)-thujopsene synthase activity,molecular_function
86937,GO:0102881,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (-)-beta-barbatene + diphosphate.",(+)-beta-barbatene synthase activity,molecular_function
86938,GO:0102882,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = beta-acoradiene + diphosphate.",beta-acoradiene synthase activity,molecular_function
86939,GO:0102883,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate.",(+)-beta-chamigrene synthase activity,molecular_function
86940,GO:0102884,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = zingiberene + diphosphoric acid.",alpha-zingiberene synthase activity,molecular_function
86941,GO:0102885,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-alpha-cuprenene + diphosphoric acid.",alpha-cuprenene synthase activity,molecular_function
86942,GO:0102887,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = beta-sesquiphellandrene + diphosphoric acid.",beta-sesquiphellandrene synthase activity,molecular_function
86943,GO:0102889,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = beta-elemene + diphosphoric acid.",beta-elemene synthase activity,molecular_function
86944,GO:0102890,"Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone = UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+. Also converts 2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose into 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside.",chalcone 4'-O-glucosyltransferase activity,molecular_function
86945,GO:0102894,Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome = H+ + cyclo-dopa 5-O-glucoside + UDP.,UDPG:cyclo-DOPA 5-O-glucosyltransferase activity,molecular_function
86946,GO:0102895,Catalysis of the reaction: 9(S)-HPODE = colneleate + H2O.,colneleate synthase activity,molecular_function
86947,GO:0102903,Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid.,gamma-terpinene synthase activity,molecular_function
86948,GO:0102904,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid.",germacrene C synthase activity,molecular_function
86949,GO:0102905,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = (+)-valencene + diphosphoric acid.",valencene synthase activity,molecular_function
86950,GO:0102906,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = (-)-7-epi-alpha-selinene + diphosphoric acid.",7-epi-alpha-selinene synthase activity,molecular_function
86951,GO:0102910,Catalysis of the reaction: 2 H+ + 2 coniferol + O2 = (+)-pinoresinol + 2 H2O. The The protein encoding this activity has been termed 'dirigent protein' because it does not express any catalytic activity and serves only to bind and orientate the coniferyl alcohol-derived free radicals.,dirigent protein activity,molecular_function
86952,GO:0102913,Catalysis of the reaction: 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine = gramine + 2 S-adenosyl-L-homocysteine + 2 H+.,3-aminomethylindole N-methyltransferase activity,molecular_function
86953,GO:0102915,Catalysis of the reaction: (+)-pinoresinol + reduced [NADPH--hemoprotein reductase] + O2 = (+)-piperitol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H+. Also catalyzes the synthesis of (+)-sesamin from (+)-piperitol.,piperitol synthase activity,molecular_function
86954,GO:0102917,Catalysis of the reaction: (S)- or (R)-reticuline + S-adenosyl-L-methionine = (S)- or (R)-laudanine + H+ + S-adenosyl-L-homocysteine.,"(R,S)-reticuline 7-O-methyltransferase activity",molecular_function
86955,GO:0102919,"Catalysis of the reaction: FMNH2 + O2 = 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid.","5,6-dimethylbenzimidazole synthase activity",molecular_function
86956,GO:0102921,Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate = H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP.,mannosylglycerate synthase activity,molecular_function
86957,GO:0102922,Catalysis of the reaction: (3R)-3-amino-3-phenylpropanoyl-CoA + baccatin III = 3'-N-debenzoyl-2'-deoxytaxol + CoA.,phenylpropanoyltransferase activity,molecular_function
86958,GO:0102923,Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = CoA + H+ + taxol.,3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity,molecular_function
86959,GO:0102930,Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid.,4-hydroxybenzoate geranyltransferase activity,molecular_function
86960,GO:0102931,"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid.","(Z,E)-alpha- farnesene synthase activity",molecular_function
86961,GO:0102933,Catalysis of the reaction: GDP-alpha-D-perosamine + 2-oxoglutarate = GDP-4-dehydro-alpha-D-rhamnose + L-glutamate.,GDP-perosamine synthase activity,molecular_function
86962,GO:0102934,"Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.",costunolide synthase activity,molecular_function
86963,GO:0102943,"Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate.","trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity",molecular_function
86964,GO:0102949,Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.,"1,2-rhamnosyltransferase activity",molecular_function
86965,GO:0102954,Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O = dalcochinin + D-glucopyranose.,dalcochinase activity,molecular_function
86966,GO:0102960,"Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H.",momilactone-A synthase [NAD(P)H] activity,molecular_function
86967,GO:0102963,Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 = (S)-corytuberine + NADP + 2 H2O.,(S)-corytuberine synthase activity,molecular_function
86968,GO:0102964,Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine = magnoflorine + S-adenosyl-L-homocysteine.,S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity,molecular_function
86969,GO:0102965,Catalysis of the reaction: a long-chain fatty acyl-CoA + 2 H+ + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP+. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,alcohol-forming long-chain fatty acyl-CoA reductase (NADP+) activity,molecular_function
86970,GO:0102967,Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP = (6E)-8-hydroxygeranial + NADPH + H+.,10-hydroxygeraniol oxidoreductase activity,molecular_function
86971,GO:0102968,Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP = (6E)-8-oxogeranial + NADPH + H+.,10-hydroxygeranial oxidoreductase activity,molecular_function
86972,GO:0102969,Catalysis of the reaction: (6E)-8-oxogeraniol + NADP = (6E)-8-oxogeranial + NADPH + H+.,10-oxogeraniol oxidoreductase activity,molecular_function
86973,GO:0102970,Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate = H+ + 7-deoxyloganate + UDP.,7-deoxyloganetic acid glucosyltransferase activity,molecular_function
86974,GO:0102971,Catalysis of the reaction: acetyl-CoA + phosphinothricin = H+ + coenzyme A(4-) + N-acetylphosphinatothricinate.,phosphinothricin N-acetyltransferase activity,molecular_function
86975,GO:0102973,Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein].,norsolorinate anthrone synthase activity,molecular_function
86976,GO:0102974,Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH.,hydroxyversicolorone reductase activity,molecular_function
86977,GO:0102975,Catalysis of the reaction: versiconol acetate + NADP = versiconal hemiacetal acetate + NADPH.,versiconal hemiacetal acetate reductase activity,molecular_function
86978,GO:0102976,Catalysis of the reaction: (2S)-versicolorone + NADP+ = 1'-hydroxyversicolorone + H+ + NADPH.,versiconal reductase activity,molecular_function
86979,GO:0102978,"Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP = 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+.",furaneol oxidoreductase activity,molecular_function
86980,GO:0102982,Catalysis of the reaction: UDP-alpha-D-glucose + NAD = H+ + UDP-3-keto-alpha-D-glucose + NADH.,UDP-3-dehydro-alpha-D-glucose dehydrogenase activity,molecular_function
86981,GO:0102983,Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan = UDP + 4 H+ + a xylogalacturonan.,"xylogalacturonan beta-1,3-xylosyltransferase activity",molecular_function
86982,GO:0102984,Catalysis of the reaction: sulfoacetaldehyde + NAD+ + H2O = sulfoacetate + NADH + 2 H+.,sulfoacetaldehyde dehydrogenase (NAD+) activity,molecular_function
86983,GO:0102985,"Catalysis of the introduction of a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9. Specific reactions include: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O; and (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.",acyl-CoA (9+3)-desaturase activity,molecular_function
86984,GO:0102986,"Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H+.",trehalose synthase activity,molecular_function
86985,GO:0102988,"Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor = 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.",acyl-CoA 15-desaturase activity,molecular_function
86986,GO:0102990,"Catalysis of the reaction: (8Z,11Z)-5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine = (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether + H+ + S-adenosyl-L-homocysteine.",5-n-alk(en)ylresorcinol O-methyltransferase activity,molecular_function
86987,GO:0102993,"Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. Also converts a (7Z,10Z)-hexadecadienoyl-containing glycerolipid into a (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid.",sn-2 acyl-lipid omega-3 desaturase (ferredoxin) activity,molecular_function
86988,GO:0102995,Catalysis of the reaction: columbianetin + NADPH + O2 + H+ = angelicin + acetone + NADP + 2 H2O.,angelicin synthase activity,molecular_function
86989,GO:0102998,"Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O = maleylacetate + sulfite + 2 H+.",4-sulfomuconolactone hydrolase activity,molecular_function
86990,GO:0103001,Catalysis of the reactions: dimethyl sulfoxide + H+ + NADH + O2 = dimethyl sulfone + H2O + NAD+ and dimethyl sulfide + H+ + NADH + O2 = dimethyl sulfoxide + H2O + NAD+.,dimethylsulfoxide oxygenase activity,molecular_function
86991,GO:0103002,Catalysis of the reaction: 16-hydroxypalmitate + NADP = H+ + 16-oxo-palmitate + NADPH.,16-hydroxypalmitate dehydrogenase activity,molecular_function
86992,GO:0103007,Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine = methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine.,indole-3-acetate carboxyl methyltransferase activity,molecular_function
86993,GO:0103011,Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate = mannosylfructose-phosphate + GDP.,mannosylfructose-phosphate synthase activity,molecular_function
86994,GO:0103012,"Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.",ferredoxin-thioredoxin reductase activity,molecular_function
86995,GO:0103015,"Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.",4-amino-4-deoxy-L-arabinose transferase activity,molecular_function
86996,GO:0103016,Catalysis of the reaction: AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H+ + L-cysteinyl-[protein].,tRNA-uridine 2-sulfurtransferase activity,molecular_function
86997,GO:0103020,Catalysis of the reaction: 1-deoxy-D-xylulose + ATP = H+ + 1-deoxy-D-xylulose 5-phosphate + ADP.,1-deoxy-D-xylulose kinase activity,molecular_function
86998,GO:0103023,Catalysis of the reaction: ITP + H2O = IDP + H+ + phosphate.,ITPase activity,molecular_function
86999,GO:0103026,Catalysis of the reaction: beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate.,fructose-1-phosphatase activity,molecular_function
87000,GO:0103031,Catalysis of the reaction:L-alanyl-L-glutamate = L-alanyl-D-glutamate.,L-Ala-D/L-Glu epimerase activity,molecular_function
87001,GO:0103036,Catalysis of the reaction: a menaquinone + NADH + H+ = a menaquinol + NAD+.,NADH dehydrogenase (menaquinone) (non-electrogenic) activity,molecular_function
87002,GO:0103037,Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH.,L-glyceraldehyde 3-phosphate reductase activity,molecular_function
87003,GO:0103039,Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.,protein methylthiotransferase activity,molecular_function
87004,GO:0103040,Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor.,aldose sugar dehydrogenase activity,molecular_function
87005,GO:0103041,Catalysis of the reaction: thiosulfate + [thioredoxin]-dithiol = sulfite + 2 H+ + [thioredoxin]-disulfide + hydrogen sulfide.,thiosulfate-thioredoxin sulfurtransferase activity,molecular_function
87006,GO:0103042,Catalysis of the reaction: 4-hydroxy-L-threonine = glycolaldehyde + glycine.,4-hydroxy-L-threonine aldolase activity,molecular_function
87007,GO:0103043,"Catalysis of the reaction: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = alpha-D-ribose 1,5-bisphosphate + H+.","phosphoribosyl 1,2-cyclic phosphate phosphodiesterase activity",molecular_function
87008,GO:0103045,Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+.,L-methionine N-acyltransferase activity,molecular_function
87009,GO:0103064,"Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+.",inositol phosphorylceramide mannosyltransferase activity,molecular_function
87010,GO:0103069,Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,17-hydroxyprogesterone 21-hydroxylase activity,molecular_function
87011,GO:0103074,Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.,glucose-6-phosphate 3-dehydrogenase activity,molecular_function
87012,GO:0103075,Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ = indole-3-acetate + carbon dioxide + NADP + H2O.,indole-3-pyruvate monooxygenase activity,molecular_function
87013,GO:0103116,Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O = alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.,ABC-type D-galactofuranose transporter,molecular_function
87014,GO:0103117,Catalysis of the reaction: a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate.,UDP-3-O-acyl-N-acetylglucosamine deacetylase activity,molecular_function
87015,GO:0103118,"Catalysis of the reaction: a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a (3R)-hydroxyacyl-[ACP] = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + holo-[ACP] + H+.",UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity,molecular_function
87016,GO:0104004,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.",cellular response to environmental stimulus,biological_process
87017,GO:0106001,"Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.",intestinal hexose absorption,biological_process
87018,GO:0106002,"A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.",mCRD-mediated mRNA stability complex,cellular_component
87019,GO:0106003,"Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine lo...",amyloid-beta complex,cellular_component
87020,GO:0106004,The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.,tRNA (guanine-N7)-methylation,biological_process
87021,GO:0106005,The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.,RNA 5'-cap (guanine-N7)-methylation,biological_process
87022,GO:0106006,"The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location.",cytoskeletal protein-membrane anchor activity,molecular_function
87023,GO:0106007,Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex.,microtubule anchoring at cell cortex of cell tip,biological_process
87024,GO:0106008,Catalysis of the reaction: 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3.,2-oxoglutaramate amidase activity,molecular_function
87025,GO:0106009,Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. Specific for the (4S) enantiomer of 4-hydroxy-2-oxoglutarate.,(4S)-4-hydroxy-2-oxoglutarate aldolase activity,molecular_function
87026,GO:0106011,Any process that regulates the localization of a protein to the medial cortex.,regulation of protein localization to medial cortex,biological_process
87027,GO:0106012,"Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex.",positive regulation of protein localization to medial cortex,biological_process
87028,GO:0106013,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip.",negative regulation of protein localization to cell cortex of cell tip,biological_process
87029,GO:0106014,"Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.",regulation of inflammatory response to wounding,biological_process
87030,GO:0106015,"Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.",negative regulation of inflammatory response to wounding,biological_process
87031,GO:0106016,"Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.",positive regulation of inflammatory response to wounding,biological_process
87032,GO:0106017,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.","phosphatidylinositol-3,4-bisphosphate phosphatase activity",molecular_function
87033,GO:0106018,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.","phosphatidylinositol-3,5-bisphosphate phosphatase activity",molecular_function
87034,GO:0106019,"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.","phosphatidylinositol-4,5-bisphosphate phosphatase activity",molecular_function
87035,GO:0106023,Any process that modulates the onset of pupariation.,regulation of pupariation,biological_process
87036,GO:0106024,"Any process that stops, prevents or reduces the rate of onset of pupariation.",negative regulation of pupariation,biological_process
87037,GO:0106025,"Any process that activates or increases the frequency, rate or extent of onset of pupariation.",positive regulation of pupariation,biological_process
87038,GO:0106026,Catalysis of the reaction: glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H+.,Gly-tRNA(Ala) deacylase activity,molecular_function
87039,GO:0106027,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.",neuron projection organization,biological_process
87040,GO:0106028,"The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.",neuron projection retraction,biological_process
87041,GO:0106029,Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.,tRNA pseudouridine synthase activity,molecular_function
87042,GO:0106030,"The collection of neuronal projections into a bundle of rods, known as a fascicle.",neuron projection fasciculation,biological_process
87043,GO:0106032,Catalysis of the reaction: uridine in snRNA = pseudouridine in snRNA. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.,snRNA pseudouridine synthase activity,molecular_function
87044,GO:0106033,A type of synapse occurring between an axon and a dendritic spine.,spine synapse,cellular_component
87045,GO:0106036,A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.,assembly of apicomedial cortex actomyosin,biological_process
87046,GO:0106037,The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell.,apicomedial cortex,cellular_component
87047,GO:0106040,"Any process that modulates the frequency, rate or extent of GABA-A receptor activity.",regulation of GABA-A receptor activity,biological_process
87048,GO:0106044,The removal of a sugar or dicarbonyl from a glycated guanine.,guanine deglycation,biological_process
87049,GO:0106046,"The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine.","guanine deglycation, glyoxal removal",biological_process
87050,GO:0106049,"Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.",regulation of cellular response to osmotic stress,biological_process
87051,GO:0106055,A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.,"mannosyl-oligosaccharide 1,2-alpha-mannosidase complex",cellular_component
87052,GO:0106056,"Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.",regulation of calcineurin-mediated signaling,biological_process
87053,GO:0106057,"Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling.",negative regulation of calcineurin-mediated signaling,biological_process
87054,GO:0106058,"Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.",positive regulation of calcineurin-mediated signaling,biological_process
87055,GO:0106059,Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.,tRNA (cytidine(56)-2'-O-ribose)-methyltransferase activity,molecular_function
87056,GO:0106060,"Any process that modulates the frequency, rate or extent of exit from mitosis.",regulation of exit from meiosis,biological_process
87057,GO:0106061,"Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.",negative regulation of exit from meiosis,biological_process
87058,GO:0106062,"Any process that activates or increases the frequency, rate or extent of exit from meiosis.",positive regulation of exit from meiosis,biological_process
87059,GO:0106063,"Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.",G protein-coupled folate receptor activity,molecular_function
87060,GO:0106064,"Any process that modulates the frequency, rate or extent of cobalamin (vitamin B12) catabolic process.",regulation of cobalamin catabolic process,biological_process
87061,GO:0106068,A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.,SUMO ligase complex,cellular_component
87062,GO:0106069,"A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.",synapsis initiation complex,cellular_component
87063,GO:0106070,"Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.",regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway,biological_process
87064,GO:0106071,"Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.",positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway,biological_process
87065,GO:0106072,"Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.",negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway,biological_process
87066,GO:0106073,Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.,"dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity",molecular_function
87067,GO:0106074,"Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.",aminoacyl-tRNA metabolism involved in translational fidelity,biological_process
87068,GO:0106075,"Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.",peptide N-succinyltransferase activity,molecular_function
87069,GO:0106076,Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.,peptide-lysine-N-succinyltransferase activity,molecular_function
87070,GO:0106078,Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.,histone succinyltransferase activity,molecular_function
87071,GO:0106080,Binding to a GATOR1 complex.,GATOR1 complex binding,molecular_function
87072,GO:0106081,"The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol.",maltose import across plasma membrane,biological_process
87073,GO:0106082,"The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol.",sucrose import across plasma membrane,biological_process
87074,GO:0106083,Any protein complex that is part of the nuclear membrane.,nuclear membrane protein complex,cellular_component
87075,GO:0106084,"A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane.",mitotic nuclear membrane microtubule tethering complex,cellular_component
87076,GO:0106089,"Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.",negative regulation of cell adhesion involved in sprouting angiogenesis,biological_process
87077,GO:0106090,"Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.",positive regulation of cell adhesion involved in sprouting angiogenesis,biological_process
87078,GO:0106091,The process of creating an elongation or projection from a glial cell.,glial cell projection elongation,biological_process
87079,GO:0106093,"A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes.",EDS1 disease-resistance complex,cellular_component
87080,GO:0106094,"A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.",nuclear membrane microtubule tethering complex,cellular_component
87081,GO:0106095,A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide.,m7G(5')pppN diphosphatase complex,cellular_component
87082,GO:0106096,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.",response to ceramide,biological_process
87083,GO:0106097,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.",cellular response to ceramide,biological_process
87084,GO:0106098,"A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.",NAGS/NAGK complex,cellular_component
87085,GO:0106099,Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.,2-keto-3-deoxy-L-rhamnonate aldolase activity,molecular_function
87086,GO:0106100,"Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate = beta-pinacene + diphosphate.",beta-pinacene synthase activity,molecular_function
87087,GO:0106101,"A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.",ER-dependent peroxisome localization,biological_process
87088,GO:0106103,"A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae.",COPII vesicles tethering complex,cellular_component
87089,GO:0106104,"Any process that modulates the frequency, rate or extent of glutamate receptor clustering.",regulation of glutamate receptor clustering,biological_process
87090,GO:0106105,Catalysis of the reaction: L-alanyl-tRNA(Thr) + H2O = tRNA(Thr) + L-alanine + H+.,Ala-tRNA(Thr) deacylase activity,molecular_function
87091,GO:0106106,The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.,cold-induced thermogenesis,biological_process
87092,GO:0106107,"Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.",regulation of (R)-mevalonic acid biosynthetic process,biological_process
87093,GO:0106108,"Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.",negative regulation of (R)-mevalonic acid biosynthetic process,biological_process
87094,GO:0106109,"Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.",positive regulation of (R)-mevalonic acid biosynthetic process,biological_process
87095,GO:0106110,"The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.",vomitoxin biosynthetic process,biological_process
87096,GO:0106117,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.",acidocalcisome organization,biological_process
87097,GO:0106118,"Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.",regulation of sterol biosynthetic process,biological_process
87098,GO:0106119,"Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.",negative regulation of sterol biosynthetic process,biological_process
87099,GO:0106120,"Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.",positive regulation of sterol biosynthetic process,biological_process
87100,GO:0106121,"Any process that activates or increases the frequency, rate or extent of a cobalamin (vitamin B12) catabolic process.",positive regulation of cobalamin catabolic process,biological_process
87101,GO:0106122,"Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin (vitamin B12) catabolic process.",negative regulation of cobalamin catabolic process,biological_process
87102,GO:0106123,"A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.",reservosome,cellular_component
87103,GO:0106124,The volume enclosed by the membranes of a reservosome.,reservosome lumen,cellular_component
87104,GO:0106125,"A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.",reservosome matrix,cellular_component
87105,GO:0106126,The lipid bilayer surrounding a reservosome.,reservosome membrane,cellular_component
87106,GO:0106128,"Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.",negative regulation of store-operated calcium entry,biological_process
87107,GO:0106129,"Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.",positive regulation of store-operated calcium entry,biological_process
87108,GO:0106130,Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.,purine phosphoribosyltransferase activity,molecular_function
87109,GO:0106134,"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.",positive regulation of cardiac muscle cell contraction,biological_process
87110,GO:0106135,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.",negative regulation of cardiac muscle cell contraction,biological_process
87111,GO:0106136,"The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.",lectin-induced modified bacterial internalization,biological_process
87112,GO:0106137,Binding to a IkappaB kinase complex.,IkappaB kinase complex binding,molecular_function
87113,GO:0106138,Binding to a Sec61 translocon complex.,Sec61 translocon complex binding,molecular_function
87114,GO:0106139,"The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.",symbiont cell surface,cellular_component
87115,GO:0106140,Binding to a P-TEFb complex.,P-TEFb complex binding,molecular_function
87116,GO:0106141,Catalysis of the reaction: dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2.,flavin prenyltransferase activity,molecular_function
87117,GO:0106142,Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.,rRNA (adenine-N1-)-methyltransferase activity,molecular_function
87118,GO:0106143,"A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).",tRNA (m7G46) methyltransferase complex,cellular_component
87119,GO:0106144,Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20.,fraxetin 5-hydroxylase activity,molecular_function
87120,GO:0106145,Catalysis of the reaction: scopoletin + 2-oxoglutarate + O2 = fraxetin + succinate + CO2.,scopoletin 8-hydroxylase activity,molecular_function
87121,GO:0106146,The chemical reactions and pathways resulting in the formation of sideretin.,sideretin biosynthesis,biological_process
87122,GO:0106147,The chemical reactions and pathways resulting in the formation of fraxetin.,fraxetin biosynthesis,biological_process
87123,GO:0106148,"The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.",4-hydroxyindole-3- carbonyl nitrile biosynthesis,biological_process
87124,GO:0106149,Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP+ + H20.,indole-3-carbonyl nitrile 4-hydroxylase activity,molecular_function
87125,GO:0106150,"The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.",zearalenone biosynthetic process,biological_process
87126,GO:0106151,Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide.,CNBH domain intrinsic ligand binding,molecular_function
87127,GO:0106154,"The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.",perithecium formation,biological_process
87128,GO:0106155,Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.,peptidyl-lysine 3-dioxygenase activity,molecular_function
87129,GO:0106156,Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.,peptidyl-lysine 4-dioxygenase activity,molecular_function
87130,GO:0106157,Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.,peptidyl-arginine 3-dioxygenase activity,molecular_function
87131,GO:0106158,Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine.,glycero-3-phosphocholine acyltransferase activity,molecular_function
87132,GO:0106162,Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H+ + phosphate.,mRNA cytidine N-acetyltransferase activity,molecular_function
87133,GO:0106166,"The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body.",spindle pole body-nuclear membrane anchor activity,molecular_function
87134,GO:0106167,The series of molecular signals mediated by the detection of extracellular ATP.,extracellular ATP signaling,biological_process
87135,GO:0106172,The volume enclosed by the membrane of a COPI-coated endocytic vesicle.,COPI-coated vesicle lumen,cellular_component
87136,GO:0106173,The volume enclosed by the membrane of a COPII-coated endocytic vesicle.,COPII-coated vesicle lumen,cellular_component
87137,GO:0106174,The volume enclosed by the membrane of a phagolysosome.,phagolysosome vesicle lumen,cellular_component
87138,GO:0106175,The lipid bylayer surrounding a phagolysosome.,phagolysosome vesicle membrane,cellular_component
87139,GO:0106176,The volume enclosed by the membrane of a clathrin-coated endocytic vesicle.,clathrin-coated endocytic vesicle lumen,cellular_component
87140,GO:0106177,Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP.,cyclic-GMP-AMP hydrolase activity,molecular_function
87141,GO:0106186,"The leaflet the plasma membrane at the cell tip that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.","cytoplasmic side of plasma membrane, cell tip",cellular_component
87142,GO:0106210,"The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris.",culmorin biosynthetic process,biological_process
87143,GO:0106211,"Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H+ + phosphate.","inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity",molecular_function
87144,GO:0106214,"Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.",regulation of vesicle fusion with Golgi apparatus,biological_process
87145,GO:0106215,"Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.",negative regulation of vesicle fusion with Golgi apparatus,biological_process
87146,GO:0106216,"Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.",positive regulation of vesicle fusion with Golgi apparatus,biological_process
87147,GO:0106217,The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine.,tRNA C3-cytosine methylation,biological_process
87148,GO:0106218,"The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).",galactosaminogalactan biosynthetic process,biological_process
87149,GO:0106219,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of zinc.",zinc ion sensor activity,molecular_function
87150,GO:0106220,"The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group.",pyocyanine biosynthetic process,biological_process
87151,GO:0106222,Binding to a long noncoding RNA (lncRNA).,lncRNA binding,molecular_function
87152,GO:0106223,"Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].",germacrene A hydroxylase activity,molecular_function
87153,GO:0106226,Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide.,peptide 2-hydroxyisobutyryltransferase activity,molecular_function
87154,GO:0106227,The glutarylation of a lysine residue in a protein.,peptidyl-lysine glutarylation,biological_process
87155,GO:0106228,Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein].,peptide glutaryltransferase activity,molecular_function
87156,GO:0106229,Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone.,histone glutaryltransferase activity,molecular_function
87157,GO:0106230,The removal of a propionyl group from a residue in a peptide or protein.,protein depropionylation,biological_process
87158,GO:0106231,Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD+ = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein-lysine depropionylase activity,molecular_function
87159,GO:0106232,A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin.,hydroxyisourate hydrolase complex,cellular_component
87160,GO:0106233,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.",glycosome organization,biological_process
87161,GO:0106234,"Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC.",outer membrane protein complex,cellular_component
87162,GO:0106235,Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate.,ceramide-1-phosphate phosphatase activity,molecular_function
87163,GO:0106236,The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.,rhamnolipid biosynthesis,biological_process
87164,GO:0106237,"Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.",arachidonate 12(R)-lipoxygenase activity,molecular_function
87165,GO:0106238,Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O.,peregrinol diphosphate synthase activity,molecular_function
87166,GO:0106239,"Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate.","9,13-epoxylabda-14-ene synthase activity",molecular_function
87167,GO:0106240,"Catalysis of the reaction: O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H+ + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase].","labd-13Z-ene-9,15,16-triol synthase activity",molecular_function
87168,GO:0106242,Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate.,kolavenyl diphosphate synthase activity,molecular_function
87169,GO:0106243,"Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene.","syn-isopimara-7,15-diene synthase activity",molecular_function
87170,GO:0106244,"Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase].",eupatolide synthase activity,molecular_function
87171,GO:0106245,Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine = L-1-phosphatidylserine + ethanolamine.,L-serine-phosphatidylethanolamine phosphatidyltransferase activity,molecular_function
87172,GO:0106249,"A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147.",Nicalin-NOMO complex,cellular_component
87173,GO:0106250,A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.,"DNA-binding transcription repressor activity, RNA polymerase III-specific",molecular_function
87174,GO:0106251,Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate.,N4-acetylcytidine amidohydrolase activity,molecular_function
87175,GO:0106254,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid.",lipid sensor activity,molecular_function
87176,GO:0106255,A hydroperoxy icosatetraenoate = a hydroxy epoxy icosatrienoate.,hydroperoxy icosatetraenoate isomerase activity,molecular_function
87177,GO:0106256,A hydroperoxy icosatetraenoate = an oxoicosatetraenoate + H2O.,hydroperoxy icosatetraenoate dehydratase activity,molecular_function
87178,GO:0106258,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline.",L-serine-phosphatidylcholine phosphatidyltransferase activity,molecular_function
87179,GO:0106259,The directional movement of a symbiont from one host cell to another.,symbiont-mediated cell-to-cell migration in host,biological_process
87180,GO:0106260,Bridging together two regions of a DNA molecule.,DNA-DNA tethering activity,molecular_function
87181,GO:0106261,Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H+ + L-methionine.,tRNA uridine(34) acetyltransferase activity,molecular_function
87182,GO:0106262,"Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.",1-acylglycerophosphoethanolamine O-acyltransferase activity,molecular_function
87183,GO:0106263,"Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.",1-acylglycerophosphoserine O-acyltransferase activity,molecular_function
87184,GO:0106264,Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein].,protein serine kinase activity (using GTP as donor),molecular_function
87185,GO:0106265,"Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA.",THPH synthase activity,molecular_function
87186,GO:0106266,"Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O.",3-chloro THPH synthase activity,molecular_function
87187,GO:0106267,"Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O.","3,5 dichloro-THPH synthase activity",molecular_function
87188,GO:0106268,"Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.","3,5-dichloro-THPH methyl transferase activity",molecular_function
87189,GO:0106271,"Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH.",D-arabinose 1-dehydrogenase (NADP+) activity,molecular_function
87190,GO:0106272,"A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).",protein localization to ERGIC,biological_process
87191,GO:0106273,The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).,cytosol to ERGIC protein transport,biological_process
87192,GO:0106274,Catalysis of the reaction: L-arginyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide.,NAD+-protein-arginine ADP-ribosyltransferase activity,molecular_function
87193,GO:0106276,Catalysis of the reaction: bilirubin IXalpha + NAD+ = biliverdin IXalpha + NADH+ H+.,biliberdin reductase (NADH) activity,molecular_function
87194,GO:0106277,Catalysis of the reaction: bilirubin IXalpha + NADP+ = biliverdin IXalpha + NADPH + H+.,biliverdin reductase (NADPH) activity,molecular_function
87195,GO:0106278,"Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process.",regulation of UDP-N-acetylglucosamine biosynthetic process,biological_process
87196,GO:0106279,"Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.",negative regulation of UDP-N-acetylglucosamine biosynthetic process,biological_process
87197,GO:0106280,"Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.",positive regulation of UDP-N-acetylglucosamine biosynthetic process,biological_process
87198,GO:0106281,Catalysis of the reaction: chenodeoxycholate + NAD+ = 7-oxolithocholate + H+ + NADH.,chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity,molecular_function
87199,GO:0106282,"Catalysis of the reaction: 3-beta,7-beta-dihydroxy-5-beta-cholan-24-oate + NAD+ = 3-beta-hydroxy-7-oxo-5-beta-cholan-24-oate + H+ + NADH.",isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity,molecular_function
87200,GO:0106283,Catalysis of the reaction: NAD+ + ursodeoxycholate = 7-oxolithocholate + H+ + NADH.,ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity,molecular_function
87201,GO:0106286,Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate.,(E)-caffeate-CoA ligase activity,molecular_function
87202,GO:0106288,"Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.",regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA,biological_process
87203,GO:0106289,"Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.",negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA,biological_process
87204,GO:0106290,Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.,trans-cinnamate-CoA ligase activity,molecular_function
87205,GO:0106291,Catalysis of the reaction: NADH + 2 O2 = H+ + NAD+ + 2 superoxide.,superoxide-generating NADH oxidase activity,molecular_function
87206,GO:0106292,Catalysis of the reaction: NADPH + 2 O2 = H+ + NADP+ + 2 superoxide.,superoxide-generating NADPH oxidase activity,molecular_function
87207,GO:0106295,"The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.",resolvin biosynthetic process,biological_process
87208,GO:0106296,"The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.",D-series resolvin biosynthetic process,biological_process
87209,GO:0106297,"The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.",E-series resolvin biosynthetic process,biological_process
87210,GO:0106298,"The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid.",13-series resolvin biosynthetic process,biological_process
87211,GO:0106299,"An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.",resolution phase response,biological_process
87212,GO:0106300,The removal of covalent cross-link between DNA and a protein.,protein-DNA covalent cross-linking repair,biological_process
87213,GO:0106301,"Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid.","arachidonate 5,6-epoxygenase activity",molecular_function
87214,GO:0106302,"Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid.","arachidonate 8,9-epoxygenase activity",molecular_function
87215,GO:0106304,"The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.",mannogen biosynthetic process,biological_process
87216,GO:0106305,"The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.",mannogen catabolic process,biological_process
87217,GO:0106309,Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,progesterone 21-hydroxylase activity,molecular_function
87218,GO:0106310,Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.,protein serine kinase activity,molecular_function
87219,GO:0106312,"Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H+.",methylenetetrahydrofolate reductase (NADH) activity,molecular_function
87220,GO:0106313,"Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H+.",methylenetetrahydrofolate reductase (NADPH) activity,molecular_function
87221,GO:0106314,Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+.,nitrite reductase (NADPH) activity,molecular_function
87222,GO:0106316,Catalysis of the reaction: NH4+ + 3 NAD+ + 2 H2O = nitrite + 3 NADH + 5 H+.,nitrite reductase (NADH) activity,molecular_function
87223,GO:0106321,Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.,S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity,molecular_function
87224,GO:0106322,Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+.,S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity,molecular_function
87225,GO:0106329,Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4+.,L-phenylalaine oxidase activity,molecular_function
87226,GO:0106330,Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.,sialate 9-O-acetylesterase activity,molecular_function
87227,GO:0106331,Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.,sialate 4-O-acetylesterase activity,molecular_function
87228,GO:0106332,Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction.,ds/ssDNA junction-specific dsDNA endonuclease activity,molecular_function
87229,GO:0106333,"Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex.",subcortical maternal complex,cellular_component
87230,GO:0106334,Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate.,3'-deoxyribose phosphate lyase activity,molecular_function
87231,GO:0106335,Catalysis of the reaction: 5-(carboxymethyl)uridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine. The methylation occurs on the modified base.,tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity,molecular_function
87232,GO:0106336,"The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm.",yolk syncytial layer development,biological_process
87233,GO:0106339,Catalysis of the reaction: cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + S-adenosyl-L-homocysteine + H+.,tRNA (cytidine(32)-2'-O-ribose)-methyltransferase activity,molecular_function
87234,GO:0106340,Catalysis of the reaction: guanosine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(34) in tRNA + H+ + S-adenosyl-L-homocysteine.,tRNA (guanosine(34)-2'-O-ribose)-methyltransferase activity,molecular_function
87235,GO:0106341,"Catalysis of the reaction: an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base + a diacylglycerol.",omega-hydroxyceramide transacylase activity,molecular_function
87236,GO:0106342,The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.,omega-hydroxyceramide biosynthetic process,biological_process
87237,GO:0106343,Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2.,glutarate dioxygenase activity,molecular_function
87238,GO:0106344,Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].,4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP,molecular_function
87239,GO:0106345,Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.,glyoxylate reductase activity,molecular_function
87240,GO:0106346,Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.,snRNA methyltransferase activity,molecular_function
87241,GO:0106347,Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+; methylates the 6th position of adenine residues with a pre-deposited 2'-O-methylation.,U2 snRNA (2'-O-methyladenosine-N6)-methyltransferase activity,molecular_function
87242,GO:0106348,Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.,U2 snRNA (adenine-N6)-methyltransferase activity,molecular_function
87243,GO:0106349,The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.,snRNA methylation,biological_process
87244,GO:0106350,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate.",all-trans-octaprenyl-diphosphate synthase activity,molecular_function
87245,GO:0106354,The set of processes involved in identifying and degrading defective or aberrant tRNAs.,tRNA surveillance,biological_process
87246,GO:0106355,"Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+.",4-hydroxybenzoate 3-monooxygenase (NADH) activity,molecular_function
87247,GO:0106356,"Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.",4-hydroxybenzoate 3-monooxygenase (NADPH) activity,molecular_function
87248,GO:0106357,Catalysis of the reaction: NAD+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADH.,glycerol-1-phosphate dehydrogenase (NAD+) activity,molecular_function
87249,GO:0106358,Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH.,glycerol-1-phosphate dehydrogenase (NADP+) activity,molecular_function
87250,GO:0106359,Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.,2-hydroxyacyl-CoA lyase activity,molecular_function
87251,GO:0106361,Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H+ + N(omega)-(L-rhamnosyl)-L-arginyl-[protein].,protein-arginine rhamnosyltransferase activity,molecular_function
87252,GO:0106362,Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.,protein-arginine N-acetylglucosaminyltransferase activity,molecular_function
87253,GO:0106363,Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein].,protein-cysteine methyltransferase activity,molecular_function
87254,GO:0106364,"Catalysis of the reaction: 4-hydroxy-3-all-trans-polyprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].",4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity,molecular_function
87255,GO:0106365,Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.,beta-carotene isomerase activity,molecular_function
87256,GO:0106366,Catalysis of the reaction: ATP + guanosine = ADP + GMP.,guanosine kinase activity,molecular_function
87257,GO:0106367,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP.,"deoxynucleoside phosphate kinase activity, dGTP as phosphate donor",molecular_function
87258,GO:0106368,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP.,"deoxynucleoside phosphate kinase activity, dTTP as phosphate donor",molecular_function
87259,GO:0106369,Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP.,"deoxynucleoside phosphate kinase activity, GTP as phosphate donor",molecular_function
87260,GO:0106370,Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.,protein-L-histidine N-pros-methyltransferase activity,molecular_function
87261,GO:0106371,Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.,fluorescent chlorophyll catabolite monooxygenase (deformylase) activity,molecular_function
87262,GO:0106372,Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.,primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity,molecular_function
87263,GO:0106373,Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD+ = 2-dehydro-3-deoxy-D-gluconate + 2 H+ + NADH.,3-deoxyglucosone dehydrogenase (NAD+) activity,molecular_function
87264,GO:0106375,Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.,deoxynucleoside triphosphate hydrolase activity,molecular_function
87265,GO:0106376,"Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.",2-hydroxyphytanoyl-CoA lyase activity,molecular_function
87266,GO:0106377,Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + H+ + diphosphate.,2-hydroxy-ATP hydrolase activity,molecular_function
87267,GO:0106378,Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + H+ + diphosphate.,2-hydroxy-dATP hydrolase activity,molecular_function
87268,GO:0106379,Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.,8-oxo-(d)RTP hydrolase activity,molecular_function
87269,GO:0106380,"Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis.",purine ribonucleotide salvage,biological_process
87270,GO:0106381,"Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.",purine deoxyribonucleotide salvage,biological_process
87271,GO:0106383,"Any process which produces a dAMP from derivatives of it, without de novo synthesis.",dAMP salvage,biological_process
87272,GO:0106384,"Any process which produces a dGMP from derivatives of it, without de novo synthesis.",dGMP salvage,biological_process
87273,GO:0106385,"Any process which produces a dIMP from derivatives of it, without de novo synthesis.",dIMP salvage,biological_process
87274,GO:0106386,Catalysis of the reaction: a (3R)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + NADH + H+.,(3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity,molecular_function
87275,GO:0106387,The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate.,'de novo' GMP biosynthetic process,biological_process
87276,GO:0106388,Catalysis of the reaction: N1-methylpseudouridine in small subunit rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in small subunit rRNA + S-methyl-5'-thioadenosine.,rRNA small subunit aminocarboxypropyltransferase activity,molecular_function
87277,GO:0106389,Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+.,ecdysteroid 22-kinase activity,molecular_function
87278,GO:0106391,"A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.",bI4 intron splicing complex,cellular_component
87279,GO:0106392,"Aprotein complex required for the splicing of intron 3 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI3 (which derives from one of the products of the splicing), the MRS1 cofactor and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.",bI3 intron splicing complex,cellular_component
87280,GO:0106396,"Any process that modulates the frequency, rate or extent of R7 cell fate commitment.",regulation of R7 cell fate commitment,biological_process
87281,GO:0106397,"Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment.",positive regulation of R7 cell fate commitment,biological_process
87282,GO:0106398,"Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment.",negative regulation of R7 cell fate commitment,biological_process
87283,GO:0106400,A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair.,double-strand break repair via transcription-associated homologous recombination,biological_process
87284,GO:0106402,"The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.",Lewis x epitope biosynthetic process,biological_process
87285,GO:0106405,Catalysis of the dephosphorylation of isoprenoid diphosphates.,isoprenoid diphosphate phosphatase activity,molecular_function
87286,GO:0106407,Catalysis of the reaction: Glc(2)Man(9)GlcNAc(2)-[protein] + H2O = GlcMan(9)GlcNAc(2)-[protein] + beta-D-glucopyranose.,Glc2Man9GlcNAc2 oligosaccharide glucosidase activity,molecular_function
87287,GO:0106408,"Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.",diadenylate cyclase activity,molecular_function
87288,GO:0106409,"Catalysis of the reaction: 3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'-5')-adenosine + H+.",cyclic-di-AMP phosphodiesterase activity,molecular_function
87289,GO:0106410,Any process involved in forming the mature 5' end of a box C/D RNA molecule.,box C/D sno(s)RNA 5'-end processing,biological_process
87290,GO:0106413,Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.,RNA dihydrouridine synthase activity,molecular_function
87291,GO:0106414,Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+.,mRNA dihydrouridine synthase activity,molecular_function
87292,GO:0106415,GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H2O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.,muramoyltetrapeptide carboxypeptidase activity,molecular_function
87293,GO:0106417,"Catalysis of the reaction: dopaminechrome = 5,6-dihydroxyindole.",dopaminechrome tautomerase activity,molecular_function
87294,GO:0106418,"Catalysis of the reaction: ATP + UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate.","UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity",molecular_function
87295,GO:0106419,Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein lipoamidase activity,molecular_function
87296,GO:0106420,Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein biotinidase activity,molecular_function
87297,GO:0106421,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamate(out) + H+(in) = L-glutamate(in) + H+(out).,L-glutamate:proton antiporter activity,molecular_function
87298,GO:0106422,Catalysis of the reaction: Zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal.,carotenoid isomerooxygenase activity,molecular_function
87299,GO:0106423,Catalysis of the reaction: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine.,tubulin-tyrosine carboxypeptidase activity,molecular_function
87300,GO:0106425,"Catalysis of the reaction: L-dopa + O2 + H2O + H+ = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.","3,4-dihydroxyphenylacetaldehyde synthase activity",molecular_function
87301,GO:0106426,"Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.",regulation of kainate selective glutamate receptor signaling pathway,biological_process
87302,GO:0106427,"Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.",negative regulation of kainate selective glutamate receptor signaling pathway,biological_process
87303,GO:0106428,"Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.",positive regulation of kainate selective glutamate receptor signaling pathway,biological_process
87304,GO:0106429,Catalysis of the reaction: 11-cis-retinol--[retinol-binding protein] + NAD+ = 11-cis-retinal--[retinol-binding protein] + NADH + H+.,11-cis-retinol dehydrogenase (NAD+) activity,molecular_function
87305,GO:0106430,(S)-dihydroorotate + a quinone = orotate + a quinol.,dihydroorotate dehydrogenase (quinone) activity,molecular_function
87306,GO:0106431,Catalysis of the reaction N6-methyl-(d)ATP + H2O = N6-methyl-(d)AMP + diphosphate + H+.,N6-methyl-(d)ATP hydrolase activity,molecular_function
87307,GO:0106432,Catalysis of the reaction: queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate.,queuosine nucleosidase activity,molecular_function
87308,GO:0106433,Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+.,O6-methyl-dGTP hydrolase activity,molecular_function
87309,GO:0106434,The reactions involved in isomerization of all trans to all cis retnal.,retinal isomerization,biological_process
87310,GO:0106435,Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+.,carboxylesterase activity,molecular_function
87311,GO:0106436,Catalysis of the reaction: a quinone + glutathione + H+ + hydrogen sulfide = a quinol + S-sulfanylglutathione.,glutathione-dependent sulfide quinone oxidoreductase activity,molecular_function
87312,GO:0106437,Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H+ + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate.,"protein-glutamic acid ligase activity, initiating",molecular_function
87313,GO:0106438,Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H+ + phosphate.,"protein-glutamic acid ligase activity, elongating",molecular_function
87314,GO:0106439,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out).,L-lysine:L-arginine antiporter activity,molecular_function
87315,GO:0110001,A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.,toxin-antitoxin complex,cellular_component
87316,GO:0110002,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.",regulation of tRNA methylation,biological_process
87317,GO:0110003,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.",regulation of tRNA C5-cytosine methylation,biological_process
87318,GO:0110004,"Any process that activates or increases the frequency, rate or extent of tRNA methylation.",positive regulation of tRNA methylation,biological_process
87319,GO:0110005,"Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.",positive regulation of tRNA C5-cytosine methylation,biological_process
87320,GO:0110009,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.",formin-nucleated actin cable organization,biological_process
87321,GO:0110010,The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.,basolateral protein secretion,biological_process
87322,GO:0110011,"Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.",regulation of basement membrane organization,biological_process
87323,GO:0110012,"Any process in which a protein is transported to, or maintained at, a P-body.",protein localization to P-body,biological_process
87324,GO:0110013,"Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.",positive regulation of aggregation involved in sorocarp development,biological_process
87325,GO:0110014,"Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.",negative regulation of aggregation involved in sorocarp development,biological_process
87326,GO:0110015,"Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.",positive regulation of elastin catabolic process,biological_process
87327,GO:0110016,"A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH...",B-WICH complex,cellular_component
87328,GO:0110017,The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.,cap-independent translational initiation of linear mRNA,biological_process
87329,GO:0110018,The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.,cap-independent translational initiation of circular RNA,biological_process
87330,GO:0110019,The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.,IRES-dependent translational initiation of circular RNA,biological_process
87331,GO:0110020,"Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.",regulation of actomyosin structure organization,biological_process
87332,GO:0110021,"The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.",cardiac muscle myoblast proliferation,biological_process
87333,GO:0110022,"Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.",regulation of cardiac muscle myoblast proliferation,biological_process
87334,GO:0110023,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.",negative regulation of cardiac muscle myoblast proliferation,biological_process
87335,GO:0110024,"Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.",positive regulation of cardiac muscle myoblast proliferation,biological_process
87336,GO:0110025,The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.,DNA strand resection involved in replication fork processing,biological_process
87337,GO:0110026,"Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.",regulation of DNA strand resection involved in replication fork processing,biological_process
87338,GO:0110027,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.",negative regulation of DNA strand resection involved in replication fork processing,biological_process
87339,GO:0110028,"Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.",positive regulation of mitotic spindle organization,biological_process
87340,GO:0110029,"Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.",negative regulation of meiosis I,biological_process
87341,GO:0110030,Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.,regulation of G2/MI transition of meiotic cell cycle,biological_process
87342,GO:0110031,Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.,negative regulation of G2/MI transition of meiotic cell cycle,biological_process
87343,GO:0110032,Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.,positive regulation of G2/MI transition of meiotic cell cycle,biological_process
87344,GO:0110033,"Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).",regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway,biological_process
87345,GO:0110034,"Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.",negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway,biological_process
87346,GO:0110036,"Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.",C2 domain binding,molecular_function
87347,GO:0110037,"Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.",regulation of nematode male tail tip morphogenesis,biological_process
87348,GO:0110038,"Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.",negative regulation of nematode male tail tip morphogenesis,biological_process
87349,GO:0110039,"Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.",positive regulation of nematode male tail tip morphogenesis,biological_process
87350,GO:0110040,The process in which the anatomical structures of the nematode pharynx are generated and organized.,nematode pharynx morphogenesis,biological_process
87351,GO:0110041,"Any process that modulates the frequency, rate or extent of nematode pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.",regulation of nematode pharynx morphogenesis,biological_process
87352,GO:0110042,"Any process that stops, prevents, or reduces the frequency, rate or extent of nematode pharynx morphogenesis.",negative regulation of nematode pharynx morphogenesis,biological_process
87353,GO:0110043,"Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.",positive regulation of nematode pharynx morphogenesis,biological_process
87354,GO:0110044,"Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.","regulation of cell cycle switching, mitotic to meiotic cell cycle",biological_process
87355,GO:0110045,"Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.","negative regulation of cell cycle switching, mitotic to meiotic cell cycle",biological_process
87356,GO:0110050,Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.,deaminated glutathione amidase activity,molecular_function
87357,GO:0110051,"A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.",metabolite repair,biological_process
87358,GO:0110052,"A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.",toxic metabolite repair,biological_process
87359,GO:0110053,"Any process that modulates the frequency, rate or extent of actin filament organization.",regulation of actin filament organization,biological_process
87360,GO:0110054,"Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.",regulation of actin filament annealing,biological_process
87361,GO:0110055,"Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.",negative regulation of actin filament annealing,biological_process
87362,GO:0110056,"Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.",positive regulation of actin filament annealing,biological_process
87363,GO:0110057,"Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.",regulation of blood vessel endothelial cell differentiation,biological_process
87364,GO:0110058,"Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.",positive regulation of blood vessel endothelial cell differentiation,biological_process
87365,GO:0110059,"Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.",negative regulation of blood vessel endothelial cell differentiation,biological_process
87366,GO:0110061,"Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.",regulation of angiotensin-activated signaling pathway,biological_process
87367,GO:0110062,"Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.",negative regulation of angiotensin-activated signaling pathway,biological_process
87368,GO:0110063,"Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.",positive regulation of angiotensin-activated signaling pathway,biological_process
87369,GO:0110064,"The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.",lncRNA catabolic process,biological_process
87370,GO:0110065,"Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.",regulation of interphase mitotic telomere clustering,biological_process
87371,GO:0110066,"Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.",negative regulation of interphase mitotic telomere clustering,biological_process
87372,GO:0110067,High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.,ammonium transmembrane transporter complex,cellular_component
87373,GO:0110068,Catalysis of the reaction: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate = (R)-glycerate + alpha-D-glucose 1-phosphate.,glucosylglycerate phosphorylase activity,molecular_function
87374,GO:0110069,The separation of a syncytial embryo into individual cells.,syncytial embryo cellularization,biological_process
87375,GO:0110070,A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.,cellularization cleavage furrow,cellular_component
87376,GO:0110071,The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.,cellularization cleavage furrow invagination front,cellular_component
87377,GO:0110072,"The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.",apical constriction involved in ventral furrow formation,biological_process
87378,GO:0110073,"Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.",regulation of apical constriction involved in ventral furrow formation,biological_process
87379,GO:0110074,"Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.",positive regulation of apical constriction involved in ventral furrow formation,biological_process
87380,GO:0110075,"Any process that modulates the frequency, rate or extent of ferroptosis.",regulation of ferroptosis,biological_process
87381,GO:0110076,"Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis.",negative regulation of ferroptosis,biological_process
87382,GO:0110077,A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.,vesicle-mediated intercellular transport,biological_process
87383,GO:0110078,"A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family.",TTT Hsp90 cochaperone complex,cellular_component
87384,GO:0110079,"Any process that modulates the frequency, rate or extent of placenta blood vessel development.",regulation of placenta blood vessel development,biological_process
87385,GO:0110080,"Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.",positive regulation of placenta blood vessel development,biological_process
87386,GO:0110081,"Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.",negative regulation of placenta blood vessel development,biological_process
87387,GO:0110082,"Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.",regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly,biological_process
87388,GO:0110083,"Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.",positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly,biological_process
87389,GO:0110085,"A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at ...",mitotic actomyosin contractile ring,cellular_component
87390,GO:0110086,"A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at ...",meiotic actomyosin contractile ring,cellular_component
87391,GO:0110088,Any apoptotic process that occurs in a hippocampal neuron.,hippocampal neuron apoptotic process,biological_process
87392,GO:0110089,Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.,regulation of hippocampal neuron apoptotic process,biological_process
87393,GO:0110090,"Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.",positive regulation of hippocampal neuron apoptotic process,biological_process
87394,GO:0110091,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.",negative regulation of hippocampal neuron apoptotic process,biological_process
87395,GO:0110092,The area of a motile nucleus closest to the direction of movement.,nucleus leading edge,cellular_component
87396,GO:0110093,The area of a motile nucleus furthest from the direction of movement.,nucleus lagging edge,cellular_component
87397,GO:0110094,Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.,polyphosphate-mediated signaling,biological_process
87398,GO:0110095,Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,cellular detoxification of aldehyde,biological_process
87399,GO:0110096,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.",cellular response to aldehyde,biological_process
87400,GO:0110097,"Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.",regulation of calcium import into the mitochondrion,biological_process
87401,GO:0110098,"Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.",positive regulation of calcium import into the mitochondrion,biological_process
87402,GO:0110099,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.",negative regulation of calcium import into the mitochondrion,biological_process
87403,GO:0110100,"The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.",spindle pole body separation,biological_process
87404,GO:0110101,The directed movement of L-valine into the vacuole across the vacuolar membrane.,L-valine transmembrane import into vacuole,biological_process
87405,GO:0110102,"The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.",ribulose bisphosphate carboxylase complex assembly,biological_process
87406,GO:0110103,A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.,RNA polymerase II termination complex,cellular_component
87407,GO:0110104,The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).,mRNA alternative polyadenylation,biological_process
87408,GO:0110105,"The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.",mRNA cleavage and polyadenylation specificity factor complex assembly,biological_process
87409,GO:0110107,"Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.",regulation of imaginal disc-derived wing vein specification,biological_process
87410,GO:0110108,"Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.",positive regulation of imaginal disc-derived wing vein specification,biological_process
87411,GO:0110109,"Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.",negative regulation of imaginal disc-derived wing vein specification,biological_process
87412,GO:0110110,"Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.",positive regulation of animal organ morphogenesis,biological_process
87413,GO:0110111,"Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.",negative regulation of animal organ morphogenesis,biological_process
87414,GO:0110115,A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.,Cdr2 medial cortical node complex,cellular_component
87415,GO:0110116,"Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.",regulation of compound eye photoreceptor cell differentiation,biological_process
87416,GO:0110117,"Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.",positive regulation of compound eye photoreceptor cell differentiation,biological_process
87417,GO:0110118,"Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.",negative regulation of compound eye photoreceptor cell differentiation,biological_process
87418,GO:0110119,"Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.",positive regulation of very-low-density lipoprotein particle clearance,biological_process
87419,GO:0110120,"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.",gamma-tubulin complex localization to nuclear side of mitotic spindle pole body,biological_process
87420,GO:0110121,"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.",gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body,biological_process
87421,GO:0110122,"The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.",myotube cell migration,biological_process
87422,GO:0110123,"Any process that modulates the frequency, rate or extent of myotube cell migration.",regulation of myotube cell migration,biological_process
87423,GO:0110124,"Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.",positive regulation of myotube cell migration,biological_process
87424,GO:0110125,"Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.",negative regulation of myotube cell migration,biological_process
87425,GO:0110126,The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.,phloem loading,biological_process
87426,GO:0110127,"The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.",phloem unloading,biological_process
87427,GO:0110128,"The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.",phloem sucrose unloading,biological_process
87428,GO:0110130,Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.,ribitol-5-phosphatase activity,molecular_function
87429,GO:0110131,"A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.",Aim21-Tda2 complex,cellular_component
87430,GO:0110134,"A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.",meiotic drive,biological_process
87431,GO:0110135,The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.,Norrin signaling pathway,biological_process
87432,GO:0110136,"The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.",protein-RNA complex remodeling,biological_process
87433,GO:0110137,"Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.",regulation of imaginal disc-derived leg joint morphogenesis,biological_process
87434,GO:0110138,"Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.",positive regulation of imaginal disc-derived leg joint morphogenesis,biological_process
87435,GO:0110139,"Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.",negative regulation of imaginal disc-derived leg joint morphogenesis,biological_process
87436,GO:0110140,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.",flagellum attachment zone organization,biological_process
87437,GO:0110141,The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.,L-glutamate import into mitochondrion,biological_process
87438,GO:0110142,"A protein complex composed of enzymes and accessory factors of the ubiquinone (CoQ) biosynthesis pathway. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K. In eukaryotes, the complex is located on the matrix face of the inner mitochondrial membrane and includes COQ3, COQ4, COQ5, COQ6, COQ7, COQ9.",ubiquinone biosynthesis complex,cellular_component
87439,GO:0110143,"A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.",magnetosome,cellular_component
87440,GO:0110145,The volume enclosed by the membrane of a magnetosome.,magnetosome lumen,cellular_component
87441,GO:0110146,The lipid bilayer surrounding a magnetosome.,magnetosome membrane,cellular_component
87442,GO:0110152,Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.,RNA NAD+-cap (NAD+-forming) hydrolase activity,molecular_function
87443,GO:0110153,Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.,RNA NAD-cap (NMN-forming) hydrolase activity,molecular_function
87444,GO:0110154,Cleavage of the 5'-cap of an RNA.,RNA decapping,biological_process
87445,GO:0110155,"Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.",NAD-cap decapping,biological_process
87446,GO:0110156,Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.,mRNA methylguanosine-cap decapping,biological_process
87447,GO:0110157,"An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.",reelin complex,cellular_component
87448,GO:0110158,A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.,calpain complex,cellular_component
87449,GO:0110159,"Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).",regulation of mitotic spindle formation (spindle phase one),biological_process
87450,GO:0110160,"Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).",negative regulation of mitotic spindle formation (spindle phase one),biological_process
87451,GO:0110161,"Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).",positive regulation of mitotic spindle formation (spindle phase one),biological_process
87452,GO:0110162,"Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).",regulation of mitotic spindle elongation (spindle phase three),biological_process
87453,GO:0110163,"Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).",negative regulation of mitotic spindle elongation (spindle phase three),biological_process
87454,GO:0110164,"Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).",positive regulation of mitotic spindle elongation (spindle phase three),biological_process
87455,GO:0110165,A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.,cellular anatomical structure,cellular_component
87456,GO:0110166,Any DNA biosynthetic process that is involved in mitochondrial DNA replication.,DNA synthesis involved in mitochondrial DNA replication,biological_process
87457,GO:0120001,"A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.",apical plasma membrane urothelial plaque,cellular_component
87458,GO:0120002,A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.,fusiform vesicle,cellular_component
87459,GO:0120003,A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.,hinge region between urothelial plaques of apical plasma membrane,cellular_component
87460,GO:0120006,"Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.",regulation of glutamatergic neuron differentiation,biological_process
87461,GO:0120007,"Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.",negative regulation of glutamatergic neuron differentiation,biological_process
87462,GO:0120008,"Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.",positive regulation of glutamatergic neuron differentiation,biological_process
87463,GO:0120009,The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).,intermembrane lipid transfer,biological_process
87464,GO:0120010,The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.,intermembrane phospholipid transfer,biological_process
87465,GO:0120011,The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).,intermembrane sterol transfer,biological_process
87466,GO:0120012,The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).,intermembrane sphingolipid transfer,biological_process
87467,GO:0120013,"Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.",lipid transfer activity,molecular_function
87468,GO:0120014,"Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",phospholipid transfer activity,molecular_function
87469,GO:0120015,"Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",sterol transfer activity,molecular_function
87470,GO:0120016,"Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",sphingolipid transfer activity,molecular_function
87471,GO:0120017,"Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",ceramide transfer activity,molecular_function
87472,GO:0120019,"Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",phosphatidylcholine transfer activity,molecular_function
87473,GO:0120020,"Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",cholesterol transfer activity,molecular_function
87474,GO:0120021,"Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",oxysterol transfer activity,molecular_function
87475,GO:0120022,"Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).",glucagon family peptide binding,molecular_function
87476,GO:0120023,"Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.",somatostatin binding,molecular_function
87477,GO:0120025,"A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.",plasma membrane bounded cell projection,cellular_component
87478,GO:0120026,"A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.",host cell uropod,cellular_component
87479,GO:0120029,"The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.",proton export across plasma membrane,biological_process
87480,GO:0120030,Any process that activates or increases the frequency of cilium beating involved in ciliary motility.,positive regulation of cilium beat frequency involved in ciliary motility,biological_process
87481,GO:0120031,"Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.",plasma membrane bounded cell projection assembly,biological_process
87482,GO:0120032,"Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.",regulation of plasma membrane bounded cell projection assembly,biological_process
87483,GO:0120033,"Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.",negative regulation of plasma membrane bounded cell projection assembly,biological_process
87484,GO:0120034,"Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.",positive regulation of plasma membrane bounded cell projection assembly,biological_process
87485,GO:0120035,"Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.",regulation of plasma membrane bounded cell projection organization,biological_process
87486,GO:0120036,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.",plasma membrane bounded cell projection organization,biological_process
87487,GO:0120039,The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.,plasma membrane bounded cell projection morphogenesis,biological_process
87488,GO:0120040,"Any process that modulates the frequency, rate or extent of macrophage proliferation.",regulation of macrophage proliferation,biological_process
87489,GO:0120041,"Any process that activates or increases the frequency, rate or extent of macrophage proliferation.",positive regulation of macrophage proliferation,biological_process
87490,GO:0120042,"Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.",negative regulation of macrophage proliferation,biological_process
87491,GO:0120043,"The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.",stereocilium shaft,cellular_component
87492,GO:0120044,The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.,stereocilium base,cellular_component
87493,GO:0120045,The organization process that preserves a stereocilium in a stable functional or structural state.,stereocilium maintenance,biological_process
87494,GO:0120046,"Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.",regulation of protein localization to medial cortical node,biological_process
87495,GO:0120047,"Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.",positive regulation of protein localization to medial cortical node,biological_process
87496,GO:0120048,Catalysis of the reaction: adenosine in U6 snRNA + S-adenosyl-L-methionine = H+ + N(6)-methyladenosine in U6 snRNA + S-adenosyl-L-homocysteine.,U6 snRNA (adenine(43)-N6)-methyltransferase activity,molecular_function
87497,GO:0120049,The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.,snRNA (adenine-N6)-methylation,biological_process
87498,GO:0120053,"Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.","ribitol beta-1,4-xylosyltransferase activity",molecular_function
87499,GO:0120054,Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).,intestinal motility,biological_process
87500,GO:0120055,Migration of ingested material along the length of the small intestine.,small intestinal transit,biological_process
87501,GO:0120056,Migration of ingested material along the length of the large intestine.,large intestinal transit,biological_process
87502,GO:0120057,"Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.",regulation of small intestinal transit,biological_process
87503,GO:0120058,"Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.",positive regulation of small intestinal transit,biological_process
87504,GO:0120059,"Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.",negative regulation of small intestinal transit,biological_process
87505,GO:0120060,"Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.",regulation of gastric emptying,biological_process
87506,GO:0120061,"Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.",negative regulation of gastric emptying,biological_process
87507,GO:0120062,"Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.",positive regulation of gastric emptying,biological_process
87508,GO:0120063,"A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.",stomach smooth muscle contraction,biological_process
87509,GO:0120064,"A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.",stomach pylorus smooth muscle contraction,biological_process
87510,GO:0120065,"A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.",pyloric antrum smooth muscle contraction,biological_process
87511,GO:0120066,"A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.",pyloric canal smooth muscle contraction,biological_process
87512,GO:0120067,"A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.",pyloric sphincter smooth muscle contraction,biological_process
87513,GO:0120068,"Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.",regulation of stomach fundus smooth muscle contraction,biological_process
87514,GO:0120069,"Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.",positive regulation of stomach fundus smooth muscle contraction,biological_process
87515,GO:0120070,"Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.",negative regulation of stomach fundus smooth muscle contraction,biological_process
87516,GO:0120071,"Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.",regulation of pyloric antrum smooth muscle contraction,biological_process
87517,GO:0120072,"Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.",positive regulation of pyloric antrum smooth muscle contraction,biological_process
87518,GO:0120073,"Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.",negative regulation of pyloric antrum smooth muscle contraction,biological_process
87519,GO:0120074,"Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.",regulation of endocardial cushion cell differentiation,biological_process
87520,GO:0120075,"Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.",positive regulation of endocardial cushion cell differentiation,biological_process
87521,GO:0120076,"Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.",negative regulation of endocardial cushion cell differentiation,biological_process
87522,GO:0120077,The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.,angiogenic sprout fusion,biological_process
87523,GO:0120078,"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.",cell adhesion involved in sprouting angiogenesis,biological_process
87524,GO:0120082,"A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.",smooth endoplasmic reticulum cisterna,cellular_component
87525,GO:0120083,"A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.",rough endoplasmic reticulum cisterna,cellular_component
87526,GO:0120084,"The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.",endothelial tip cell filopodium assembly,biological_process
87527,GO:0120086,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate.","(3S)-(+)-asterisca-2(9),6-diene synthase activity",molecular_function
87528,GO:0120091,"Catalysis of the reaction: jasmonate + 2-oxoglutarate + O2 = (1R,2R)-12-hydroxyjasmonate + succinate + CO2.",jasmonic acid hydrolase activity,molecular_function
87529,GO:0120092,Catalysis of the reaction: 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O. (2E)-butenoyl-CoA is also known as crotonoyl-CoA.,(2E)-butenoyl-CoA hydratase activity,molecular_function
87530,GO:0120093,"Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.",regulation of peptidyl-lysine crotonylation,biological_process
87531,GO:0120094,Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.,negative regulation of peptidyl-lysine crotonylation,biological_process
87532,GO:0120095,"An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.",vacuole-isolation membrane contact site,cellular_component
87533,GO:0120097,A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.,glycosylphosphatidylinositol-mannosyltransferase II complex,cellular_component
87534,GO:0120098,"A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo path...",procentriole,cellular_component
87535,GO:0120099,"A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.",procentriole replication complex,cellular_component
87536,GO:0120100,"A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA...",bacterial-type flagellum motor,cellular_component
87537,GO:0120101,"A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanel...",bacterial-type flagellum stator complex,cellular_component
87538,GO:0120102,"A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.",bacterial-type flagellum secretion apparatus,cellular_component
87539,GO:0120103,"A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.",centriolar subdistal appendage,cellular_component
87540,GO:0120104,The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.,"mitotic actomyosin contractile ring, proximal layer",cellular_component
87541,GO:0120105,"The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.","mitotic actomyosin contractile ring, intermediate layer",cellular_component
87542,GO:0120106,"The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.","mitotic actomyosin contractile ring, distal actin filament layer",cellular_component
87543,GO:0120107,"The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.",bacterial-type flagellum rotor complex,cellular_component
87544,GO:0120108,Catalysis of the reaction: a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H+.,DNA-3'-diphospho-5'-guanosine diphosphatase activity,molecular_function
87545,GO:0120109,"The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.",mitotic telomere clustering and tethering at nuclear periphery,biological_process
87546,GO:0120110,"The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.",interphase mitotic telomere clustering,biological_process
87547,GO:0120111,"All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.",neuron projection cytoplasm,cellular_component
87548,GO:0120112,The directed movement of UDP-glucose from cytosol to endoplasmic reticulum.,UDP-glucose transmembrane transport into endoplasmic reticulum,biological_process
87549,GO:0120113,"A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but ...",cytoplasm to vacuole targeting by the NVT pathway,biological_process
87550,GO:0120114,"A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which compris...",Sm-like protein family complex,cellular_component
87551,GO:0120115,"A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.",Lsm2-8 complex,cellular_component
87552,GO:0120116,The formation of mature glucagon by proteolysis of the precursor proglucagon.,glucagon processing,biological_process
87553,GO:0120117,The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).,T cell meandering migration,biological_process
87554,GO:0120118,A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.,flagella connector,cellular_component
87555,GO:0120119,A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.,flagellum attachment zone,cellular_component
87556,GO:0120120,A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).,bilobe structure,cellular_component
87557,GO:0120121,A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body.,tripartite attachment complex,cellular_component
87558,GO:0120122,"The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals.",prolactin metabolic process,biological_process
87559,GO:0120123,"A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.",ubiquitin activating enzyme complex,cellular_component
87560,GO:0120124,"A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes.",membrane fusion priming complex,cellular_component
87561,GO:0120125,"A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.",PNGase complex,cellular_component
87562,GO:0120126,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.",response to copper ion starvation,biological_process
87563,GO:0120127,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.",response to zinc ion starvation,biological_process
87564,GO:0120132,"Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.",positive regulation of apoptotic process in bone marrow cell,biological_process
87565,GO:0120133,"Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches.",negative regulation of actin cortical patch assembly,biological_process
87566,GO:0120134,The portion of the axoneme that is close to the base of the cilium.,proximal portion of axoneme,cellular_component
87567,GO:0120135,The portion of the axoneme that is close to the tip of the cilium.,distal portion of axoneme,cellular_component
87568,GO:0120136,Catalysis of the reaction: ATP + dUMP = ADP + dUDP.,dUMP kinase activity,molecular_function
87569,GO:0120141,"Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor signaling pathway.",regulation of ecdysone receptor signaling pathway,biological_process
87570,GO:0120142,"Any process that activates or increases the frequency, rate or extent of any ecdysone receptor signaling pathway.",positive regulation of ecdysone receptor signaling pathway,biological_process
87571,GO:0120143,"Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor signaling pathway.",negative regulation of ecdysone receptor signaling pathway,biological_process
87572,GO:0120145,"A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.",protein localization to basal ectoplasmic specialization,biological_process
87573,GO:0120146,"Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.",sulfatide binding,molecular_function
87574,GO:0120147,Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.,formylglycine-generating oxidase activity,molecular_function
87575,GO:0120148,"A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.",host cell centrosome,cellular_component
87576,GO:0120149,"A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.",host cell peroxisome,cellular_component
87577,GO:0120152,Binding to an outer dynein arm in the presence of calcium.,calcium-dependent outer dynein arm binding,molecular_function
87578,GO:0120153,Binding to a carbohydrate in the presence of calcium.,calcium-dependent carbohydrate binding,molecular_function
87579,GO:0120154,"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.",negative regulation of ERBB4 signaling pathway,biological_process
87580,GO:0120155,"A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.",MIH complex,cellular_component
87581,GO:0120157,"A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.",PAR polarity complex,cellular_component
87582,GO:0120158,"Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.",positive regulation of collagen catabolic process,biological_process
87583,GO:0120159,Catalysis of the reaction: a uridine in rRNA = a pseudouridine in rRNA. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.,rRNA pseudouridine synthase activity,molecular_function
87584,GO:0120160,Binding to an intraciliary transport particle A (IFT A) complex.,intraciliary transport particle A binding,molecular_function
87585,GO:0120161,"Any process that modulates the frequency, rate or extent of cold-induced thermogenesis.",regulation of cold-induced thermogenesis,biological_process
87586,GO:0120162,"Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.",positive regulation of cold-induced thermogenesis,biological_process
87587,GO:0120163,"Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.",negative regulation of cold-induced thermogenesis,biological_process
87588,GO:0120164,"The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakd...",conidium germination,biological_process
87589,GO:0120165,"The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.",perithecium development,biological_process
87590,GO:0120166,"The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium.",protoperithecium formation,biological_process
87591,GO:0120168,The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception.,detection of hot stimulus involved in thermoception,biological_process
87592,GO:0120169,The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception.,detection of cold stimulus involved in thermoception,biological_process
87593,GO:0120170,Binding to an intraciliary transport particle B (IFT B) complex.,intraciliary transport particle B binding,molecular_function
87594,GO:0120171,"A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit).",Cdc24p-Far1p-Gbetagamma complex,cellular_component
87595,GO:0120174,"A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate b...",stress-induced homeostatically regulated protein degradation pathway,biological_process
87596,GO:0120175,"Any process that modulates the frequency, rate or extent of the torso signaling pathway.",regulation of torso signaling pathway,biological_process
87597,GO:0120176,"Any process that activates or increases the frequency, rate or extent of the torso signaling pathway.",positive regulation of torso signaling pathway,biological_process
87598,GO:0120177,"Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.",negative regulation of torso signaling pathway,biological_process
87599,GO:0120178,"The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.",steroid hormone biosynthetic process,biological_process
87600,GO:0120179,The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.,adherens junction disassembly,biological_process
87601,GO:0120180,The disaggregation of a cell-substrate junction into its constituent components.,cell-substrate junction disassembly,biological_process
87602,GO:0120181,"The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity.",focal adhesion disassembly,biological_process
87603,GO:0120182,"Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.",regulation of focal adhesion disassembly,biological_process
87604,GO:0120183,"Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.",positive regulation of focal adhesion disassembly,biological_process
87605,GO:0120184,"Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.",negative regulation of focal adhesion disassembly,biological_process
87606,GO:0120185,"The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex.",MBF transcription complex assembly,biological_process
87607,GO:0120186,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.",negative regulation of protein localization to chromatin,biological_process
87608,GO:0120187,"Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.",positive regulation of protein localization to chromatin,biological_process
87609,GO:0120188,"Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.",regulation of bile acid secretion,biological_process
87610,GO:0120189,"Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.",positive regulation of bile acid secretion,biological_process
87611,GO:0120190,"Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.",negative regulation of bile acid secretion,biological_process
87612,GO:0120191,"Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.",negative regulation of termination of RNA polymerase II transcription,biological_process
87613,GO:0120192,"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.",tight junction assembly,biological_process
87614,GO:0120193,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.",tight junction organization,biological_process
87615,GO:0120194,Any process involved in the dehiscence of an anther to release the pollen grains contained within it.,regulation of anther dehiscence,biological_process
87616,GO:0120195,"Any process that activates or increases the frequency, rate or extent of anther dehiscence.",positive regulation of anther dehiscence,biological_process
87617,GO:0120196,"Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.",negative regulation of anther dehiscence,biological_process
87618,GO:0120197,The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways.,mucociliary clearance,biological_process
87619,GO:0120198,Any process that increases the size of an imaginal disc-derived wing.,positive regulation of imaginal disc-derived wing size,biological_process
87620,GO:0120199,The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.,cone photoreceptor outer segment,cellular_component
87621,GO:0120200,The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.,rod photoreceptor outer segment,cellular_component
87622,GO:0120201,"Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane.",cone photoreceptor disc membrane,cellular_component
87623,GO:0120202,"Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment.",rod photoreceptor disc membrane,cellular_component
87624,GO:0120203,The volume enclosed by the membrane of a rod photoreceptor cell disc membrane.,rod photoreceptor disc lumen,cellular_component
87625,GO:0120204,Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.,methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity,molecular_function
87626,GO:0120205,"The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR.",photoreceptor proximal connecting cilium,cellular_component
87627,GO:0120206,"The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability.",photoreceptor distal connecting cilium,cellular_component
87628,GO:0120207,The process of selecting and or marking the position where endocytosis will occur.,"endocytosis, site selection",biological_process
87629,GO:0120208,Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons.,telodendria,cellular_component
87630,GO:0120209,Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.,cone telodendria,cellular_component
87631,GO:0120210,Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.,rod telodendria,cellular_component
87632,GO:0120211,Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.,proacrosomal vesicle fusion,biological_process
87633,GO:0120212,A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.,sperm head-tail coupling apparatus,cellular_component
87634,GO:0120213,"Any process that modulates the frequency, rate or extent of histidine biosynthetic process.",regulation of histidine biosynthetic process,biological_process
87635,GO:0120214,"Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.",negative regulation of histidine biosynthetic process,biological_process
87636,GO:0120215,"Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.",positive regulation of histidine biosynthetic process,biological_process
87637,GO:0120216,A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer.,matrilin complex,cellular_component
87638,GO:0120217,"A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).",DNA gyrase complex,cellular_component
87639,GO:0120218,A quorum sensing process that is modulated by some interaction with a host cell or organism.,host interaction involved in quorum sensing,biological_process
87640,GO:0120219,"The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina.",subapical part of cell,cellular_component
87641,GO:0120220,The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster.,basal body patch,cellular_component
87642,GO:0120221,"Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.",maintenance of ciliary planar beating movement pattern,biological_process
87643,GO:0120222,"Any process that modulates the frequency, rate or extent of blastocyst development.",regulation of blastocyst development,biological_process
87644,GO:0120223,"The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.",larynx morphogenesis,biological_process
87645,GO:0120224,"The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.",larynx development,biological_process
87646,GO:0120225,"Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.",coenzyme A binding,molecular_function
87647,GO:0120226,"Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.",succinyl-CoA binding,molecular_function
87648,GO:0120227,"Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.",acyl-CoA binding,molecular_function
87649,GO:0120228,A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules.,outer dynein arm docking complex,cellular_component
87650,GO:0120229,"A process in which a protein is transported to, or maintained in, a location within a motile cilium.",protein localization to motile cilium,biological_process
87651,GO:0120230,Binds to and increases the activity of a recombinase.,recombinase activator activity,molecular_function
87652,GO:0120231,A protein complex that binds to a recombinase and incrseases its activity.,DNA recombinase auxiliary factor complex,cellular_component
87653,GO:0120232,"The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.",prenyl-FMNH2 biosynthetic process,biological_process
87654,GO:0120233,"Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.",prenyl-FMNH2 binding,molecular_function
87655,GO:0120234,A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle.,stereocilium coat,cellular_component
87656,GO:0120235,"Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.","regulation of post-translational protein targeting to membrane, translocation",biological_process
87657,GO:0120236,"Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.","negative regulation of post-translational protein targeting to membrane, translocation",biological_process
87658,GO:0120238,The carbohydrate rich layer at the outermost periphery of a sperm cell.,sperm glycocalyx,cellular_component
87659,GO:0120239,"The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated.",vascular endothelial glycocalyx,cellular_component
87660,GO:0120240,The carbohydrate rich layer at the outermost periphery of a platelet.,platelet glycocalyx,cellular_component
87661,GO:0120241,"Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.",2-iminobutanoate/2-iminopropanoate deaminase activity,molecular_function
87662,GO:0120242,Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4+.,2-iminobutanoate deaminase activity,molecular_function
87663,GO:0120243,Catalysis of the reaction: 2-iminopropanoate + H2O = NH4+ + pyruvate.,2-iminopropanoate deaminase activity,molecular_function
87664,GO:0120249,"The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae.",lateral wall of outer hair cell,cellular_component
87665,GO:0120250,Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,fatty acid omega-hydroxylase activity,molecular_function
87666,GO:0120251,"The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.",hydrocarbon biosynthetic process,biological_process
87667,GO:0120252,"The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.",hydrocarbon metabolic process,biological_process
87668,GO:0120253,"The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.",hydrocarbon catabolic process,biological_process
87669,GO:0120254,"The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).",olefinic compound metabolic process,biological_process
87670,GO:0120255,"The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).",olefinic compound biosynthetic process,biological_process
87671,GO:0120256,"The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).",olefinic compound catabolic process,biological_process
87672,GO:0120257,The acetylation of peptidyl-threonine.,peptidyl-threonine acetylation,biological_process
87673,GO:0120259,A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb.,7SK snRNP,cellular_component
87674,GO:0120260,"A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape.",ciliary microtubule quartet,cellular_component
87675,GO:0120261,"Any process that modulates the frequency, rate, extent or location of heterochromatin organization.",regulation of heterochromatin organization,biological_process
87676,GO:0120262,"Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization.",negative regulation of heterochromatin organization,biological_process
87677,GO:0120263,"Any process that activates or increases the frequency, rate or extent of heterochromatin organization.",positive regulation of heterochromatin organization,biological_process
87678,GO:0120264,"Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.",regulation of chromosome attachment to the nuclear envelope,biological_process
87679,GO:0120265,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.",negative regulation of chromosome attachment to the nuclear envelope,biological_process
87680,GO:0120266,"Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.",positive regulation of chromosome attachment to the nuclear envelope,biological_process
87681,GO:0120267,"The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles.",pellicular membrane,cellular_component
87682,GO:0120268,"The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme.",paraflagellar rod assembly,biological_process
87683,GO:0120269,A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.,ciliary centrin arm,cellular_component
87684,GO:0120270,"Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.",regulation of nuclear mRNA surveillance of meiosis-specific transcripts,biological_process
87685,GO:0120271,"Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.",negative regulation of nuclear mRNA surveillance of meiosis-specific transcripts,biological_process
87686,GO:0120272,"Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.",positive regulation of nuclear mRNA surveillance of meiosis-specific transcripts,biological_process
87687,GO:0120273,"The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.",ciliary centrin arm assembly,biological_process
87688,GO:0120274,"Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity.",virus coreceptor activity,molecular_function
87689,GO:0120275,"The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.",cerebral blood circulation,biological_process
87690,GO:0120276,"Any process that modulates the frequency, rate or extent of cerebral blood circulation.",regulation of cerebral blood circulation,biological_process
87691,GO:0120277,"Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.",positive regulation of cerebral blood circulation,biological_process
87692,GO:0120278,"Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.",negative regulation of cerebral blood circulation,biological_process
87693,GO:0120279,"A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.",Z granule,cellular_component
87694,GO:0120280,"The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.",ciliary pro-basal body,cellular_component
87695,GO:0120281,"A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.",autolysosome membrane,cellular_component
87696,GO:0120282,The volume that is enclosed within the autolysosome single-membrane.,autolysosome lumen,cellular_component
87697,GO:0120283,Binding to a protein serine/threonine kinase.,protein serine/threonine kinase binding,molecular_function
87698,GO:0120284,Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid.,tryptophan binding,molecular_function
87699,GO:0120285,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine.",tyrosine sensor activity,molecular_function
87700,GO:0120286,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan.",tryptophan sensor activity,molecular_function
87701,GO:0120290,A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.,stalled replication fork localization to nuclear periphery,biological_process
87702,GO:0120291,Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.,negative regulation of mitotic recombination-dependent replication fork processing,biological_process
87703,GO:0120292,"Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.",positive regulation of mitotic recombination-dependent replication fork processing,biological_process
87704,GO:0120293,"An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.",dynein axonemal particle,cellular_component
87705,GO:0120294,Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4+.,peptide serotonyltransferase activity,molecular_function
87706,GO:0120295,Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4+.,histone serotonyltransferase activity,molecular_function
87707,GO:0120296,Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4+.,peptide dopaminyltransferase activity,molecular_function
87708,GO:0120297,Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4+.,histone dopaminyltransferase activity,molecular_function
87709,GO:0120298,Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4+.,peptide noradrenalinyltransferase activity,molecular_function
87710,GO:0120299,Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].,peptide histaminyltransferase activity,molecular_function
87711,GO:0120300,Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[protein].,peptide lactyltransferase (CoA-dependent) activity,molecular_function
87712,GO:0120301,Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[histone].,histone lactyltransferase (CoA-dependent) activity,molecular_function
87713,GO:0120302,Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.,background adaptation,biological_process
87714,GO:0120303,Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.,visually-mediated background adaptation,biological_process
87715,GO:0120304,Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.,integument-mediated background adaptation,biological_process
87716,GO:0120305,"Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.",regulation of pigmentation,biological_process
87717,GO:0120306,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.",cellular response to actin cytoskeletal stress,biological_process
87718,GO:0120307,An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.,Hechtian strand,cellular_component
87719,GO:0120308,"The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.",axonemal outer doublet assembly,biological_process
87720,GO:0120309,A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.,cilium attachment to cell body,biological_process
87721,GO:0120310,"The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites.",amastigogenesis,biological_process
87722,GO:0120311,A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.,ciliary pro-basal body maturation,biological_process
87723,GO:0120312,The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.,ciliary basal body segregation,biological_process
87724,GO:0120313,"Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.",regulation of oocyte karyosome formation,biological_process
87725,GO:0120314,"Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.",negative regulation of oocyte karyosome formation,biological_process
87726,GO:0120315,"Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.",positive regulation of oocyte karyosome formation,biological_process
87727,GO:0120316,"The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).",sperm flagellum assembly,biological_process
87728,GO:0120317,"The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.",sperm mitochondrial sheath assembly,biological_process
87729,GO:0120318,"The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system.",olfactory sociosexual communication,biological_process
87730,GO:0120319,Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.,long-chain fatty acid omega-1 hydroxylase activity,molecular_function
87731,GO:0120320,The myosin-based contraction and retraction of a lateral pseudopodium.,lateral pseudopodium retraction,biological_process
87732,GO:0120321,The region of the nuclear envelope situated in close proximity to a nuclear pore complex.,nuclear envelope adjacent to nuclear pore complex,cellular_component
87733,GO:0120322,"A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.",lipid modification by small protein conjugation,biological_process
87734,GO:0120323,The process in which one or more ubiquitin groups are added to a lipid.,lipid ubiquitination,biological_process
87735,GO:0120324,"The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.",procyclogenesis,biological_process
87736,GO:0120325,Binding to a NuRD complex.,NuRD complex binding,molecular_function
87737,GO:0120326,Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.,appressorium-mediated entry into host,biological_process
87738,GO:0120327,A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.,telopode,cellular_component
87739,GO:0120328,"Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.",ATP-dependent DNA (cytosine-5-)-methyltransferase activity,molecular_function
87740,GO:0120329,"A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.",protein localization to centriolar satellite,biological_process
87741,GO:0120330,"A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals...",rixosome complex,cellular_component
87742,GO:0120331,The developmental process pertaining to the initial formation of an endothelial tube.,endothelial tube formation,biological_process
87743,GO:0120332,"The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth.",host-mediated modulation of oral microbiota composition,biological_process
87744,GO:0120333,"The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is most proximal to the base of the cilium. Radial spoke 1 (RS1), similarly to radial spoke 2, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS1 is connected to the tail of the inner dynein arm a/d.",radial spoke 1,cellular_component
87745,GO:0120334,"The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is immediately distal to radial spoke 1 (RS1). Radial spoke 2 (RS2), similarly to RS1, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS2 is connected to the tail of the inner dynein arm c.",radial spoke 2,cellular_component
87746,GO:0120335,"Radial spoke 3 (RS3), when present, is the most distal of each group of radial spokes, whether grouped as triplets or doublets. RS3 has significantly different morphology and protein composition than RS1 and RS2 and also extends at a slant from the microtubule doublet, rather than perpendicularly like RS1 and RS2. In some organisms (e.g. Chlamydomonas and Sarcophaga bullata), RS3 is represented only as a stump attached to the A-microtubule lacking the rest of the stalk structure and entirely ...",radial spoke 3,cellular_component
87747,GO:0120336,The portion of the radial spoke 1 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.,radial spoke head 1,cellular_component
87748,GO:0120337,The portion of the radial spoke 2 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.,radial spoke head 2,cellular_component
87749,GO:0120338,The portion of the radial spoke 3 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.,radial spoke head 3,cellular_component
87750,GO:0120339,The short portion of the radial spoke that is directly anchored to the A microtubule of an axonemal microtubule doublet.,radial spoke base,cellular_component
87751,GO:0120340,The short portion of the radial spoke 1 (RS1) that is directly anchored to the A microtubule of an axonemal microtubule doublet.,radial spoke base 1,cellular_component
87752,GO:0120341,The short portion of the radial spoke 2 (RS2) that is directly anchored to the A microtubule of an axonemal microtubule doublet.,radial spoke base 2,cellular_component
87753,GO:0120342,The short portion of the radial spoke 3 (RS3 )that is directly anchored to the A microtubule of an axonemal microtubule doublet.,radial spoke base 3,cellular_component
87754,GO:0120343,The radial spoke neck is a complex that connects the spoke stalk to the head.,radial spoke neck,cellular_component
87755,GO:0120500,A heterodimeric E1 complex that activates the ubiquitin-like protein NEDD8. In humans the subunits are NAE1 (also known as APPBP1) and UBA3.,NAE1-UBA3 complex,cellular_component
87756,GO:0120501,Catalysis of the reaction: L-methionyl-[F-actin] + NADPH + O2 + H+ = L-methionyl-(R)-S-oxide-[F-actin] + NADP+ + H2O.,F-actin monooxygenase activity,molecular_function
87757,GO:0120502,Catalysis of the reaction: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].,fatty acid omega-1 hydroxylase activity,molecular_function
87758,GO:0120503,Catalysis of the reaction: an (omega-1)-ethyl medium-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid omega-1 hydroxylase activity,molecular_function
87759,GO:0120504,"A heterodimeric complex capable of glycosyltransferase activity required for the elongation of heparan sulfate chains. In humans, the complex consists of EXT1 and EXT2. In Drosophila, the complex consists of ttv and sotv.",EXT1-EXT2 complex,cellular_component
87760,GO:0120505,Catalysis of the reaction: L-lysyl79-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl79-[histone H3] + S-adenosyl-L-homocysteine.,histone H3K79 monomethyltransferase activity,molecular_function
87761,GO:0120506,"Catalysis of the reaction: L-lysyl79-[histone H3] + 2 S-adenosyl-L-methionine = 2H+ + N6,N6-methyl-L-lysyl79-[histone H3] + 2 S-adenosyl-L-homocysteine.",histone H3K79 dimethyltransferase activity,molecular_function
87762,GO:0120507,"A protein complex that catalyzes the base-exchange of a guanine residue with queuine at the wobble position of the anticodon of tRNAs. The eukaryotic tRNA-guanine transglycosylase exists as a heterodimer of a catalytic subunit (QTRT1 in humans) and an accessory subunit (QTRT2 in humans), whereas the bacterial enzyme is homodimeric.",tRNA-guanine transglycosylase complex,cellular_component
87763,GO:0120508,"A protein complex capable of catalyzing the reaction of GTP and mannose-1-phosphate to form GDP-mannose. The complex is a homodimer in most bacteria and a heterodimer in most eukaryotes. In humans, it is composed of a catalytic beta subunit (GMPPB) and a regulatory alpha subunit (GMPPA).",GDP-mannose pyrophosphorylase complex,cellular_component
87764,GO:0120509,Catalysis of the reaction: (R)-glycerate + NADP+ = 3-hydroxypyruvate + NADPH + H+.,hydroxypyruvate reductase (NADPH) activity,molecular_function
87765,GO:0120510,"A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in mitochondria. In S. cerevisiae, it consists of Isa1 and Isa2. In humans it consists of ISCA1 and ISCA2. Additional proteins may be present.",mitochondrial [4Fe-4S] assembly complex,cellular_component
87766,GO:0120511,"Catalysis of the reaction: methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase].",methyl farnesoate epoxidase activity,molecular_function
87767,GO:0120512,"Catalysis of the reaction: (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase].",farnesoate epoxidase activity,molecular_function
87768,GO:0120513,"A protein complex capable of catalysing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.",2-(3-amino-3-carboxypropyl)histidine synthase complex,cellular_component
87769,GO:0120514,Catalysis of the reaction: a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose = a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + H+ + UDP.,2-hydroxyflavanone C-glucosyltransferase activity,molecular_function
87770,GO:0120515,Catalysis of the reaction: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate.,fatty acid-CoA ligase activity,molecular_function
87771,GO:0120516,Catalysis of the reaction: a diacylglycerol + H2O = a fatty acid + a monoacylglycerol + H+.,diacylglycerol lipase activity,molecular_function
87772,GO:0120517,Catalysis of the reaction: inositol pentakisphosphate + ATP = inositol hexakisphosphate + ADP + H+.,inositol pentakisphosphate kinase activity,molecular_function
87773,GO:0120518,Catalysis of the reaction: acetyl-CoA + N-terminal L-methionyl-[protein] = CoA + H+ + N-terminal N(alpha)-acetyl-L-methionyl-[protein].,protein N-terminal-methionine acetyltransferase activity,molecular_function
87774,GO:0120519,Catalysis of the reaction: acetyl-CoA + N-terminal L-methionyl-[tubulin] = CoA + H+ + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]. The N-terminus of both alpha- and beta-tubulin are acetylated.,tubulin N-terminal-methionine acetyltransferase activity,molecular_function
87775,GO:0120520,"Catalysis of the reaction: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O. Note that the substrate is a free fatty acid, not a fatty acyl chain within a sphingolipid.",free fatty acid 2-hydroxylase activity,molecular_function
87776,GO:0120521,"Catalysis of the reaction: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O.",4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity,molecular_function
87777,GO:0120522,"Catalysis of the reaction: a short-chain 2,3-saturated fatty acyl-CoA + O2 = a short-chain (2E)-enoyl-CoA + H2O2.",short-chain fatty acyl-CoA oxidase activity,molecular_function
87778,GO:0120523,"Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + O2 = a medium-chain (2E)-enoyl-CoA + H2O2.",medium-chain fatty acyl-CoA oxidase activity,molecular_function
87779,GO:0120524,"Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + O2 = a long-chain (2E)-enoyl-CoA + H2O2.",long-chain fatty acyl-CoA oxidase activity,molecular_function
87780,GO:0120525,Catalysis of the reaction: choline = acetaldehyde + trimethylamine.,choline trimethylamine lyase activity,molecular_function
87781,GO:0120526,Catalysis of the reaction: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].,homomethionine N-monooxygenase activity,molecular_function
87782,GO:0120527,"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate = a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H+.",aliphatic desulfoglucosinolate sulfotransferase activity,molecular_function
87783,GO:0120528,Catalysis of the reactions: a 2-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O and a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O.,2-(omega-methylthio)alkylmalate dehydratase activity,molecular_function
87784,GO:0120529,Catalysis of the reaction: (-)-secoisolariciresinol + 2 NAD+ = (-)-matairesinol + 2 H(+) + 2 NADH.,secoisolariciresinol dehydrogenase activity,molecular_function
87785,GO:0120530,"The chemical reactions and pathways resulting in the formation of UDP-alpha-D-glucose, a substance composed of alpha-D-glucose in glycosidic linkage with uridine diphosphate.",UDP-alpha-D-glucose biosynthetic process,biological_process
87786,GO:0120531,Catalysis of chain elongation of prenyl diphosphate substrates via one or more condensation reactions with isopentenyl diphosphate to generate linear polymers with defined chain lengths.,prenyl diphosphate synthase activity,molecular_function
87787,GO:0120532,"The formation of a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate) on specific serine residues of a core protein, on to which dermatan sulfate, chondroitin sulfate, heparan sulfate or heparin glycosaminoglycans may be assembled to synthesise the corresponding proteoglycan.",glycosaminoglycan-protein linkage region biosynthetic process,biological_process
87788,GO:0120533,Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD(P)+ + H2O = (2R)-3-phosphoglycerate + NAD(P)H + 2 H+.,"glyceraldehyde-3-phosphate dehydrogenase (non-phosphorylating, [NAD(P)+] ) activity",molecular_function
87789,GO:0120534,"Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan sulfate.",dermatan sulfotransferase activity,molecular_function
87790,GO:0120536,Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate = 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate.,heptaprenylglyceryl phosphate synthase activity,molecular_function
87791,GO:0120537,Catalysis of the reaction: a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine.,3-demethylubiquinone 3-O-methyltransferase activity,molecular_function
87792,GO:0120538,"Catalysis of the reaction: 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ = 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.",2-methoxy-6-polyprenolphenol 4-hydroxylase activity,molecular_function
87793,GO:0120539,Catalysis of the reaction: a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H+ = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2.,4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity,molecular_function
87794,GO:0120542,Catalysis of the reaction: ethanol + NAD+ = acetaldehyde + NADH + H+.,ethanol dehydrogenase (NAD+) activity,molecular_function
87795,GO:0120543,Catalysis of a reaction that alters the macromolecular conformation of a molecule.,macromolecular conformation isomerase activity,molecular_function
87796,GO:0120544,Catalysis of a reaction that alters the conformation or assembly of a polypeptide.,polypeptide conformation or assembly isomerase activity,molecular_function
87797,GO:0120545,Catalysis of a reaction that alters the conformation of a nucleic acid.,nucleic acid conformation isomerase activity,molecular_function
87798,GO:0120546,Catalysis of an oxidation-reduction (redox) reaction in which a reducing C-O-C group acts as acceptor.,"oxidoreductase activity, reducing C-O-C group as acceptor",molecular_function
87799,GO:0120547,"Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.",heme A synthase activity,molecular_function
87800,GO:0120548,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H+.",phosphatidylinositol phospholipase C activity,molecular_function
87801,GO:0120549,Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages to branches with degrees of polymerization of three or four glucose residues in limit dextrin.,"limit dextrin alpha-1,6-maltotetraose-hydrolase activity",molecular_function
87802,GO:0120550,Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the second transcribed nucleotide of mRNAs and snRNAs.,methyltransferase cap2 activity,molecular_function
87803,GO:0120551,"The chemical reactions and pathways resulting in the formation of succinyl-CoA from 2-oxoglutarate.  In most organisms, this pathway is part of the TCA cycle and comprises a series of three reactions carried out by a multisubunit complex called the '2-oxoglutarate dehydrogenase complex', even though 2-oxoglutarate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: 2-oxoglutarate + coenzyme A + NAD+ -> succinyl-CoA + CO2 +...",2-oxoglutarate decarboxylation to succinyl-CoA,biological_process
87804,GO:0120552,"The chemical reactions and pathways resulting in the formation of a branched-chain acyl-CoA by the oxidative decarboxylation of a branched-chain alpha-keto acid derived from L-leucine, L-isoleucine or L-valine. This pathway comprises a series of three reactions carried out by a multisubunit complex called the 'branched-chain alpha-keto acid dehydrogenase complex', even though branched-chain alpha-keto acid dehydrogenase activity describes only one of those reactions. The combination of the th...",branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA,biological_process
87805,GO:0120553,"Catalysis of the reaction: (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+.",farnesal dehydrogenase (NAD+) activity,molecular_function
87806,GO:0120554,Catalysis of the reaction: (2S)-2-aminobutanoate + 2-oxoglutarate = 2-oxobutanoate + L-glutamate.,(2S)-2-aminobutanoate:2-oxoglutarate transaminase activity,molecular_function
87807,GO:0120555,Catalysis of the reaction: a ubiquinone + NADH + H+ = a ubiquinol + NAD+.,NADH dehydrogenase (ubiquinone) (non-electrogenic) activity,molecular_function
87808,GO:0120556,Catalysis of the dephosphorylation of polyprenyl diphosphates.,polyprenyl diphosphate phosphatase activity,molecular_function
87809,GO:0120557,"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + phosphate + H+.",farnesyl diphosphatase activity,molecular_function
87810,GO:0120558,"Catalysis of the hydrolysis of a lysoglycerophospholipid, removing the acyl chain at the sn-1 position to yield a glycerophospho-compound and a free fatty acid.",lysophospholipase A1 activity,molecular_function
87811,GO:0120559,Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H+.,phosphatidylethanolamine lysophospholipase A1 activity,molecular_function
87812,GO:0120560,Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H+.,phosphatidylserine lysophospholipase A1 activity,molecular_function
87813,GO:0120561,Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H+.,phosphatidylinositol lysophospholipase A1 activity,molecular_function
87814,GO:0120562,Catalysis of the transfer of a mannosyl residue to GlcNAc(2)-PP-Dol bearing 0-8 mannoses during synthesis of the N-glycan precursor.,GlcNAc(2)-PP-Dol mannosyltransferase activity,molecular_function
87815,GO:0120563,"Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to Man(1)-GlcN-acyl-PI, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage. This transfers the second mannose to the GPI precursor.","dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity",molecular_function
87816,GO:0120564,"Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to Man(2)-GlcN-acyl-PI, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. This transfers the third mannose to the GPI precursor.","dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity",molecular_function
87817,GO:0120565,"Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to Man(3)-GlcN-acyl-PI, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. This transfers a fourth mannose to the GPI precursor, which is only present in some organisms/cell types.","dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity",molecular_function
87818,GO:0120566,"Catalysis of the reaction: menadiol + (2E,6E,10E)-geranylgeranyl diphosphate = menaquinol-4 + diphosphate.",menadiol geranylgeranyltransferase activity,molecular_function
87819,GO:0120567,"Catalysis of the reaction: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine = 4-(trimethylamino)butanal + glycine.",hydroxytrimethyllysine aldolase activity,molecular_function
87820,GO:0120568,Catalysis of the reaction: (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+.,(R)-2-hydroxyglutarate (NAD+) dehydrogenase activity,molecular_function
87821,GO:0120569,Catalysis of the hydrolysis of a phospholipid.,phospholipase activity,molecular_function
87822,GO:0120570,Catalysis of the hydrolysis of a sphingophospholipid.,sphingophospholipase activity,molecular_function
87823,GO:0120571,Catalysis of the reaction: N6-[(R)-dihydrolipoyl]-L-lysyl-[protein] + glutaryl-CoA = CoA + N6-[(R)-S8-glutaryldihydrolipoyl]-L-lysyl-[protein].,dihydrolipoyllysine-residue glutaryltransferase activity,molecular_function
87824,GO:0120572,Catalysis of the reaction: (S)-lactate + O2 = pyruvate + H2O2.,L-lactate oxidase activity,molecular_function
87825,GO:0120573,"Catalysis of the hydrolysis of the ester bond in a fatty acid ester of a hydroxy fatty acid (FAHFA), yielding a free fatty acid and a hydroxy fatty acid. FAHFAs are a class of endogenous bioactive signaling lipids in which a fatty acid is esterified to a hydroxyl group on a second fatty acid backbone.",FAHFA hydrolase activity,molecular_function
87826,GO:0120574,Any process leading to the modification of the GPI-anchor after its transfer and attachment to a protein.,GPI anchor remodelling,biological_process
87827,GO:0120575,The chemical reactions and pathways resulting in the breakdown of L-dopa.,L-dopa catabolic process,biological_process
87828,GO:0120576,"The chemical reactions and pathways resulting in the formation of 1,2-dehydro-N-beta-alanyldopamine via N-beta-alanyldopamine (NBAD). In insects, these sclerotizing precursors are involved in the cross-linking of cuticular proteins hardening (sclerotizing) and pigmenting the cuticle.","1,2-dehydro-N-beta-alanyldopamine biosynthetic process",biological_process
87829,GO:0120577,"The chemical reactions and pathways resulting in the formation of 1,2-dehydro-N-acetyldopamine via N-acetyldopamine (NADA). In insects, these sclerotizing precursors are involved in the cross-linking of cuticular proteins hardening (sclerotizing) and pigmenting the cuticle.","1,2-dehydro-N-acetyldopamine biosynthetic process",biological_process
87830,GO:0140001,The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum.,morula formation,biological_process
87831,GO:0140002,A histone reader that recognizes a histone H3 trimethylated at lysine 4.,histone H3K4me3 reader activity,molecular_function
87832,GO:0140003,A histone reader that recognizes a histone H3 trimethylated at lysine 36.,histone H3K36me3 reader activity,molecular_function
87833,GO:0140004,A histone reader that recognizes a histone H3 serotonylated at glutamine 5.,histone H3Q5ser reader activity,molecular_function
87834,GO:0140005,A histone reader that recognizes a histone H4 dimethylated at lysine 20.,histone H4K20me2 reader activity,molecular_function
87835,GO:0140006,"A histone reader that specifically binds either to an unmodified histone H3 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.",histone H3 reader activity,molecular_function
87836,GO:0140007,"A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2.",KICSTOR complex,cellular_component
87837,GO:0140008,"A histone reader that specifically binds either to an unmodified histone H4 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.",histone H4 reader activity,molecular_function
87838,GO:0140009,"The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol.",L-aspartate import across plasma membrane,biological_process
87839,GO:0140010,Enables the transfer of D-aspartate from one side of a membrane to the other.,D-aspartate transmembrane transporter activity,molecular_function
87840,GO:0140011,A histone reader that recognizes a histone H4 acetylated at lysine 12.,histone H4K12ac reader activity,molecular_function
87841,GO:0140012,A histone reader that recognizes a histone H4 acetylated at lysine 5.,histone H4K5ac reader activity,molecular_function
87842,GO:0140013,One of the two nuclear divisions that occur as part of the meiotic cell cycle.,meiotic nuclear division,biological_process
87843,GO:0140014,"A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",mitotic nuclear division,biological_process
87844,GO:0140015,A histone reader that recognizes a histone H3 acetylated at lysine 14.,histone H3K14ac reader activity,molecular_function
87845,GO:0140017,A histone reader that recognizes a histone H3 crotonylated at lysine 18.,histone H3K18cr reader activity,molecular_function
87846,GO:0140018,Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.,regulation of cytoplasmic translational fidelity,biological_process
87847,GO:0140019,A histone reader that recognizes a histone H3 crotonylated at lysine 9.,histone H3K9cr reader activity,molecular_function
87848,GO:0140020,A protein complex that possesses DNA methyltransferase activity.,DNA methyltransferase complex,cellular_component
87849,GO:0140021,"The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial ADP transmembrane transport,biological_process
87850,GO:0140022,A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria.,cnida,cellular_component
87851,GO:0140023,The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.,tRNA adenosine deamination to inosine,biological_process
87852,GO:0140024,"The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination.",plus-end-directed endosome transport along mitotic spindle midzone microtubule,biological_process
87853,GO:0140026,"The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network.",contractile vacuole dissociation from plasma membrane,biological_process
87854,GO:0140027,The directed movement of the contractile vacuole to a specific location.,contractile vacuole localization,biological_process
87855,GO:0140028,"The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes.",pore formation during contractile vacuole discharge,biological_process
87856,GO:0140029,The cellular processes that contribute to exocytosis.,exocytic process,biological_process
87857,GO:0140030,Binding to a protein upon post-translation modification of the target protein.,modification-dependent protein binding,molecular_function
87858,GO:0140031,Binding to a protein upon phosphorylation of the target protein.,phosphorylation-dependent protein binding,molecular_function
87859,GO:0140032,Binding to a protein upon glycosylation of the target protein.,glycosylation-dependent protein binding,molecular_function
87860,GO:0140033,Binding to a protein upon acetylation of the target protein.,acetylation-dependent protein binding,molecular_function
87861,GO:0140034,Binding to a protein upon methylation of the target protein.,methylation-dependent protein binding,molecular_function
87862,GO:0140035,A molecular adaptor that recognizes and binds a target protein containing a ubiquitin-like modification and that brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.,ubiquitin-like protein reader activity,molecular_function
87863,GO:0140036,A molecular adaptor recognizes and binds a target protein containing a ubiquitination modification and brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.,ubiquitin-modified protein reader activity,molecular_function
87864,GO:0140037,A molecular adaptor that recognizes and binds a target protein containing a SUMO modification and that brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.,SUMO-modified protein reader activity,molecular_function
87865,GO:0140038,A histone reader that recognizes a histone H3 crotonylated at lysine 27.,histone H3K27cr reader activity,molecular_function
87866,GO:0140039,The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.,cell-cell adhesion in response to extracellular stimulus,biological_process
87867,GO:0140040,The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.,mitochondrial polycistronic RNA processing,biological_process
87868,GO:0140041,Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,cellular detoxification of methylglyoxal,biological_process
87869,GO:0140042,"A process that results in the assembly, arrangement of constituent parts of a lipid droplet.",lipid droplet formation,biological_process
87870,GO:0140043,"Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge.",lipid droplet localization to prospore membrane leading edge,biological_process
87871,GO:0140044,A histone reader that recognizes a histone H3 acetylated at lysine 18.,histone H3K18ac reader activity,molecular_function
87872,GO:0140046,A histone reader that recognizes a histone H4 acetylated at lysine 16.,histone H4K16ac reader activity,molecular_function
87873,GO:0140047,Species or cell-type specific extracellular matrices that are different from the two main types of extracellular matrices: the interstitial ECM and the basement membrane ECM in metazoa.,specialized extracellular matrix,cellular_component
87874,GO:0140048,"The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region.",manganese ion export across plasma membrane,biological_process
87875,GO:0140049,"Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition.",regulation of endocardial cushion to mesenchymal transition,biological_process
87876,GO:0140050,"Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition.",negative regulation of endocardial cushion to mesenchymal transition,biological_process
87877,GO:0140051,"Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition.",positive regulation of endocardial cushion to mesenchymal transition,biological_process
87878,GO:0140052,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus.",cellular response to oxidised low-density lipoprotein particle stimulus,biological_process
87879,GO:0140053,"The process of transcribing and translating the mitochondrial genome (mtDNA) to produce at least a subset of oxidative phosphorylation (OXPHOS) proteins, 2 rRNAs, and mitochondrial tRNAs, which are critical for ATP production. Protein maturation is included when required to form an active form of a product from an inactive precursor form.",mitochondrial gene expression,biological_process
87880,GO:0140054,"A histone reader that specifically binds either to an unmodified histone H2A or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.",histone H2A reader activity,molecular_function
87881,GO:0140055,A histone reader that recognizes a histone H4 acetylated at lysine 8.,histone H4K8ac reader activity,molecular_function
87882,GO:0140056,The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.,organelle localization by membrane tethering,biological_process
87883,GO:0140058,"The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.",neuron projection arborization,biological_process
87884,GO:0140059,The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.,dendrite arborization,biological_process
87885,GO:0140060,"The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.",axon arborization,biological_process
87886,GO:0140063,A histone reader that specifically binds either to an unmodified histone.,unmodified histone reader activity,molecular_function
87887,GO:0140064,Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide.,peptide crotonyltransferase activity,molecular_function
87888,GO:0140065,Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.,peptide butyryltransferase activity,molecular_function
87889,GO:0140066,The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.,peptidyl-lysine crotonylation,biological_process
87890,GO:0140067,The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.,peptidyl-lysine butyrylation,biological_process
87891,GO:0140068,Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.,histone crotonyltransferase activity,molecular_function
87892,GO:0140069,Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.,histone butyryltransferase activity,molecular_function
87893,GO:0140070,Enables the energy-independent facilitated diffusion of H2O2 through a transmembrane aqueous pore or channel.,hydrogen peroxide channel activity,molecular_function
87894,GO:0140071,"A histone reader that specifically binds either to an unmodified histone H2B or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.",histone H2B reader activity,molecular_function
87895,GO:0140072,A histone reader that recognizes a histone H3 acetylated at lysine 9.,histone H3K9ac reader activity,molecular_function
87896,GO:0140073,"A structural molecule ativity that mediates an organism's attachment to an environmental substrate via stable, non-selective binding by a protein to an external surface. Examples includes proteins used by insects to anchor pupae to surfaces.",bioadhesive activity,molecular_function
87897,GO:0140074,"A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endoc...",cardiac endothelial to mesenchymal transition,biological_process
87898,GO:0140075,Any process that controls lipoprotein transport.,regulation of lipoprotein transport,biological_process
87899,GO:0140076,"Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.",negative regulation of lipoprotein transport,biological_process
87900,GO:0140077,Any process that activates or increases the rate or extent of lipoprotein transport.,positive regulation of lipoprotein transport,biological_process
87901,GO:0140078,"Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.",class I DNA-(apurinic or apyrimidinic site) endonuclease activity,molecular_function
87902,GO:0140081,Binding to a glycosylated region of a protein.,glycosylated region protein binding,molecular_function
87903,GO:0140082,"Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.",SUMO-ubiquitin ligase activity,molecular_function
87904,GO:0140083,Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.,ATP-dependent protein-DNA unloader activity,molecular_function
87905,GO:0140084,"The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum.",sexual macrocyst formation,biological_process
87906,GO:0140085,Catalysis of the reaction: acetyl-CoA + a L-amino acid = CoA + an N-acetyl-L-amino-acid. In some cases other acetyl containing molecules can be used as donor.,L-amino-acid N-acetyltransferase activity,molecular_function
87907,GO:0140086,The structure located at the interface of the basement membrane and interstitial extracellular matrix and anchoring the two types of ECM to one another.,basement membrane/interstitial matrix interface,cellular_component
87908,GO:0140087,Catalysis of the reaction: acetaldehyde + NAD+ + H2O = acetate + NADH + 2 H+.,acetaldehyde dehydrogenase (NAD+) activity,molecular_function
87909,GO:0140088,Catalysis of the reaction: acetaldehyde + NADP+ + H2O = acetate + NADPH + 2 H+.,acetaldehyde dehydrogenase (NADP+) activity,molecular_function
87910,GO:0140089,The accumulation and maintenance in cells of proteins. Protein reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.,protein storage,biological_process
87911,GO:0140090,Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins.,membrane curvature sensor activity,molecular_function
87912,GO:0140091,"A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof.",mBAF complex,cellular_component
87913,GO:0140092,"A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their o...",bBAF complex,cellular_component
87914,GO:0140093,"An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C.",esBAF complex,cellular_component
87915,GO:0140094,The action of a molecule that contributes to the structural integrity of cytoplasmic lattice of the the mammalian ooplasm.,structural constituent of cytoplasmic lattice,molecular_function
87916,GO:0140095,"Fibrous structures of the mammalian ooplasm that store ribosomes and maternal proteins in insoluble form to prevent their degradation, activation and nuclear transfer.",cytoplasmic lattice,cellular_component
87917,GO:0140096,Catalytic activity that acts to modify a protein.,"catalytic activity, acting on a protein",molecular_function
87918,GO:0140097,Catalytic activity that acts to modify DNA.,"catalytic activity, acting on DNA",molecular_function
87919,GO:0140098,Catalytic activity that acts to modify RNA.,"catalytic activity, acting on RNA",molecular_function
87920,GO:0140099,A process in which an organism inhibits or disrupts fibrinolysis in another organism via the action of a venom. Fibrinolysis is the solubilization of fibrin in the bloodstream. Anti-fibrinolytic proteins reduce bleeding at the bite or sting site of the prey.,venom-mediated suppression of fibrinolysis,biological_process
87921,GO:0140100,"Catalysis of the exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.",lytic exotransglycosylase activity,molecular_function
87922,GO:0140101,Catalytic activity that acts to modify a tRNA.,"catalytic activity, acting on a tRNA",molecular_function
87923,GO:0140102,Catalytic activity that acts to modify a ribosomal RNA.,"catalytic activity, acting on a rRNA",molecular_function
87924,GO:0140103,Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein.,"catalytic activity, acting on a glycoprotein",molecular_function
87925,GO:0140104,Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.,molecular carrier activity,molecular_function
87926,GO:0140105,"The series of molecular signals initiated by interleukin-10 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-10-mediated signaling pathway,biological_process
87927,GO:0140106,"A feeding behavior that involves the ingestion of blood. Hematophagous animals have mouth parts and chemical agents for penetrating vascular structures in the skin of hosts. To overcome natural hemostasis, vasoconstriction, inflammation, and pain sensation in the host, hematophagous animals pre-inject chemical substances with anesthetic and/or anticoagulant properties.",hematophagy,biological_process
87928,GO:0140107,Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity potassium ion transmembrane transporter activity,molecular_function
87929,GO:0140108,Enables the transfer of D-glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.,high-affinity D-glucose transmembrane transporter activity,molecular_function
87930,GO:0140109,A histone reader that recognizes a histone H3 monomethylated at lysine 4.,histone H3K4me1 reader activity,molecular_function
87931,GO:0140110,"A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.",transcription regulator activity,molecular_function
87932,GO:0140111,Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).,[choline trimethylamine-lyase]-activating enzyme activity,molecular_function
87933,GO:0140112,"The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.",extracellular vesicle biogenesis,biological_process
87934,GO:0140113,"The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.",extracellular microvesicle biogenesis,biological_process
87935,GO:0140114,Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,cellular detoxification of fluoride,biological_process
87936,GO:0140115,"The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.",export across plasma membrane,biological_process
87937,GO:0140116,"The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region.",fluoride export across plasma membrane,biological_process
87938,GO:0140117,A histone reader that recognizes a histone H4 monomethylated at lysine 20.,histone H4K20me1 reader activity,molecular_function
87939,GO:0140118,A histone reader that recognizes a histone H3 acetylated at lysine 23.,histone H3K23ac reader activity,molecular_function
87940,GO:0140119,A histone reader that recognizes a histone H3 acetylated at lysine 27.,histone H3K27ac reader activity,molecular_function
87941,GO:0140120,A histone reader that recognizes a histone H2A ubiquitinated at lysine 15.,histone H2AK15ub reader activity,molecular_function
87942,GO:0140121,"The aggregation, arrangement and bonding together of a set of components to form a Lewy body.",Lewy body formation,biological_process
87943,GO:0140122,"Any process that modulates the frequency, rate or extent of Lewy body formation.",regulation of Lewy body formation,biological_process
87944,GO:0140123,"Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation.",negative regulation of Lewy body formation,biological_process
87945,GO:0140124,"Any process that activates or increases the frequency, rate or extent of Lewy body formation.",positive regulation of Lewy body formation,biological_process
87946,GO:0140125,"The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol.",thiamine import across plasma membrane,biological_process
87947,GO:0140126,A histone reader that recognizes a histone H2A acetylated at lysine 15.,histone H2AK15ac reader activity,molecular_function
87948,GO:0140127,A histone reader that recognizes a histone H3 dimethylate at arginine 8. The methylation can be symmetrical or asymmetrical.,histone H3R8me2 reader activity,molecular_function
87949,GO:0140128,"A histone reader that specifically binds either to an unmodified histone H1 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation.",histone H1 reader activity,molecular_function
87950,GO:0140129,A histone reader that recognizes a histone H3 acetylated at lysine 56.,histone H3K56ac reader activity,molecular_function
87951,GO:0140130,A histone reader that recognizes a histone H2A acetylated at lysine 5.,histone H2AK5ac reader activity,molecular_function
87952,GO:0140131,"Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.",positive regulation of lymphocyte chemotaxis,biological_process
87953,GO:0140132,Binding to an iron-sulfur cluster and delivering it to an acceptor molecule.,iron-sulfur cluster chaperone activity,molecular_function
87954,GO:0140134,A process in which an organism alters or subverts the circulation of blood in another organism via the action of a venom.,venom-mediated perturbation of blood circulation,biological_process
87955,GO:0140135,Enables the transmembrane transfer of a monoatomic cation by a channel that opens in response to a mechanical stress.,mechanosensitive monoatomic cation channel activity,molecular_function
87956,GO:0140136,A process in which an organism alters or subverts a nervous system process in another organism via the action of a venom.,venom-mediated perturbation of nervous system process,biological_process
87957,GO:0140137,A process in which an organism alters or subverts a muscular process in another organism via the action of a venom.,venom-mediated perturbation of muscle system process,biological_process
87958,GO:0140138,A process by which an organism effects a change that impairs the structure or function of an anatomical structure in another organism via the action of a venom. Venoms are injected into the prey by a bite or a sting.,venom-mediated disruption of anatomical structure in another organism,biological_process
87959,GO:0140139,"The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens.",solid phase of basement membrane,cellular_component
87960,GO:0140140,"The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial guanine nucleotide transmembrane transport,biological_process
87961,GO:0140141,"The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial potassium ion transmembrane transport,biological_process
87962,GO:0140142,Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein.,nucleocytoplasmic carrier activity,molecular_function
87963,GO:0140143,"Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane.",collagenous component of basement membrane,cellular_component
87964,GO:0140144,"The non-collagenous compartment of the solid phase in basement membrane ECM, including glycoproteins like laminins or nidogens.",non-collagenous component of basement membrane,cellular_component
87965,GO:0140145,The directed movement of copper ions out of the vacuole across the vacuolar membrane.,copper ion export from vacuole,biological_process
87966,GO:0140146,The directed movement of calcium cations into the vacuole across the vacuolar membrane.,calcium ion import into vacuole,biological_process
87967,GO:0140147,The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol.,zinc ion export from vacuole,biological_process
87968,GO:0140148,Gel formed of proteglycans filling the basement membrane ECM space.,gel phase of basement membrane,cellular_component
87969,GO:0140149,"The non-collagenous component of interstitial extracellular matrices, including glycoprotein like fibronectin and elastin.",non-collagenous component of interstitial matrix,cellular_component
87970,GO:0140150,"Hydrogel filling the interstitial extracellular matrix space. Composed of proteoglycans such as hyaluronan and lectin-binding proteoglycans, SPOCK proteoglycans and small leucin-rich proteoglycan (SLRP).",gel phase of interstitial matrix,cellular_component
87971,GO:0140151,"The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin.",solid phase of interstitial matrix,cellular_component
87972,GO:0140152,"Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens.",collagenous component of interstitial matrix,cellular_component
87973,GO:0140153,"A supramolecular complex formed by fibril-associated collagens with interrupted triple helices (FACIT) that associate with collagen fibrils and forms a link on large, banded fibrils.",FACIT collagen complex,cellular_component
87974,GO:0140154,Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane.,chicken-wire-like collagen network,cellular_component
87975,GO:0140156,Collagen that contains multiple triple-helix domains with interruptions.,multiplexin collagen trimer,cellular_component
87976,GO:0140157,"The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.",ammonium import across plasma membrane,biological_process
87977,GO:0140158,A family of collagens containing multiple von Willebrand factor A (vWA) domains.,von-Willerbrand-factor-A-domain-rich collagen trimer,cellular_component
87978,GO:0140159,"The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region.",borate export across plasma membrane,biological_process
87979,GO:0140161,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).,monocarboxylate:sodium symporter activity,molecular_function
87980,GO:0140162,"A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates bradykinin-dependent signaling, concomittantly reducing blood pressure in the bitten/stung organism. This can take place via several mechanisms that affect endogenous bradykinin: either increasing its release by kallikrein-like proteases, increasing bradykinin action by potentiation, or inhibiting bradykinin degradation.",venom-mediated vasodilation by activation of bradykinin receptor signaling pathway,biological_process
87981,GO:0140163,A process in which an organism inhibits or disrupts vasodilation via the action of a venom that suppresses bradykinin-dependent signaling.,venom-mediated suppression of bradykinin-dependent vasodilation,biological_process
87982,GO:0140164,"Binding to a Golgi transport complex, a multisubunit tethering complex of the CATCHR family.",COG complex binding,molecular_function
87983,GO:0140165,"A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that activates nitric oxide-cGMP-mediated signaling, concomittantly reducing blood pressure in the bitten/stung organism.",venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling,biological_process
87984,GO:0140166,"A process in which an organism initiates, promotes, or enhances vasodilation via the action of a venom that prevents angiotensin maturation, concomittantly reducing blood pressure in the bitten/stung organism.",venom-mediated vasodilation via suppression of angiotensin maturation,biological_process
87985,GO:0140167,"The aggregation, arrangement and bonding together of a set of components to form a histone locus body.",histone locus body assembly,biological_process
87986,GO:0140168,A ribonucleoprotein granule located in the nucleus.,nuclear ribonucleoprotein granule,cellular_component
87987,GO:0140169,Catalysis of the reaction: a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+.,3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity,molecular_function
87988,GO:0140170,Catalysis of the reaction: (R)-lactate + FAD + H+ = FADH2 + pyruvate.,D-lactate dehydrogenase (FAD) activity,molecular_function
87989,GO:0140171,Catalysis of the reaction: (S)-lactate + A = AH(2) + pyruvate.,L-lactate dehydrogenase activity,molecular_function
87990,GO:0140172,A histone reader that recognizes a histone H2A phosphorylated at threonine 120.,histone H2AT120pho reader activity,molecular_function
87991,GO:0140173,A histone reader that recognizes a histone H2A phosphorylated at serine 139.,histone H2AS139pho reader activity,molecular_function
87992,GO:0140174,Catalysis of the activity: a (2R)-2-hydroxycarboxylate + FAD + H+ = a 2-oxocarboxylate + FADH2.,(2R)-2-hydroxycarboxylate dehydrogenase activity,molecular_function
87993,GO:0140175,Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + NAD+ = a 2-oxocarboxylate + NADH + H+.,(2R)-2-hydroxyacid dehydrogenase (NAD+) activity,molecular_function
87994,GO:0140176,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.",positive regulation of pyruvate decarboxylation to acetyl-CoA,biological_process
87995,GO:0140177,"The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex, vesicle or organelle.",membrane-membrane adaptor activity,molecular_function
87996,GO:0140178,"The leaflet of the cis-Golgi network membrane directly contacts the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where glycosylation, cargo sorting, or interactions with resident Golgi proteins occur.",lumenal side of cis-Golgi network membrane,cellular_component
87997,GO:0140179,"The leaflet of the cis-Golgi network membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site of interactions with cytosolic proteins, including those for vesicle tethering, fusion, and Golgi-associated trafficking activities.",cytoplasmic side of cis-Golgi network membrane,cellular_component
87998,GO:0140180,"The binding activity of a protein that contributes to the stable formation of a centriole by forming persistent structures, or templates, upon which other centriolar proteins assemble.",centriole scaffold activity,molecular_function
87999,GO:0140181,"A process in which a host organism initiates, promotes, or enhances the normal execution of viral RNA-templated transcription, the synthesis of either RNA on a RNA template.",host-mediated activation of viral RNA-templated transcription,biological_process
88000,GO:0140182,"The process of freeing aborted or stalled RNA polymerase (RNAP), which dissociates it from nucleic acids and allows RNAP to reinitiate another transcription cycle. The freed mRNA is not used for further transcription.",recycling of RNA polymerase,biological_process
88001,GO:0140183,"A process in which an organism promotes the narrowing (constriction) of blood vessels, by inhibiting the widening (dilation) of blood vessels in another organism via the action of a venom that activates endothelin receptor signaling pathway, concomittantly increasing blood pressure in the bitten/stung organism.",venom-mediated vasoconstriction via activation of endothelin receptor signaling pathway,biological_process
88002,GO:0140184,A process in which an organism inhibits or disrupts blood coagulation in another organism by suppression of the intrinsic pathway via the action of a venom. A common mechanism is the blocking the activity of host coagulation Factor XIIa (F12).,"venom-mediated suppression of blood coagulation, intrinsic pathway",biological_process
88003,GO:0140185,The formation of heterochromatin into a heterochromatin domain by a process mediated by a small interfering siRNA at the silent mating-type loci.,siRNA-mediated silent mating type cassette region heterochromatin formation,biological_process
88004,GO:0140186,Catalysis of the reaction: an acyl-CoA + L-lysyl-[protein] = N6-acyl-L-lysyl-[protein] + CoA + H+.,protein N-acyltransferase activity,molecular_function
88005,GO:0140187,Catalysis of the reaction: acetyl-CoA + histone H1-4 L-lysine (position 34) = CoA + histone H1-4 N6-acetyl-L-lysine (position 34).,histone H1-4K34 acetyltransferase activity,molecular_function
88006,GO:0140188,Catalysis of the reaction: S-adenosyl-L-methionine + a histone H1 = S-adenosyl-L-homocysteine + a methylated histone H1.,histone H1 methyltransferase activity,molecular_function
88007,GO:0140189,Catalysis of the reaction: S-adenosyl-L-methionine + histone H1-4 L-lysine (position 26) = S-adenosyl-L-homocysteine + histone H1-4 N6-methyl-L-lysine (position 26).,H1-4K26 methyltransferase activity,molecular_function
88008,GO:0140190,Catalysis of the transfer of a phosphate group to a histone H1.,histone H1 kinase activity,molecular_function
88009,GO:0140191,Catalysis of the reaction: histone H1-4-serine (position 27) + ATP = histone H1-4-phosphoserine (position 27) + ADP.,histone H1-4S187 kinase activity,molecular_function
88010,GO:0140197,Catalysis of the reaction: histone H1-4-serine (position 187) + ATP = histone H1-4-phosphoserine (position 187) + ADP.,histone H1-4S27 kinase activity,molecular_function
88011,GO:0140198,Catalysis of the reaction: histone H1-4-serine (position 35) + ATP = histone H1-4-phosphoserine (position 35) + ADP.,histone H1-4S35 kinase activity,molecular_function
88012,GO:0140201,"The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol.",urea import across plasma membrane,biological_process
88013,GO:0140202,"The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol.",polyamine import across plasma membrane,biological_process
88014,GO:0140203,"The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol.",spermidine import across plasma membrane,biological_process
88015,GO:0140204,"The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol.",pyridoxal import across plasma membrane,biological_process
88016,GO:0140205,"The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol.",oligopeptide import across plasma membrane,biological_process
88017,GO:0140206,"The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.",dipeptide import across plasma membrane,biological_process
88018,GO:0140207,"The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.",tripeptide import across plasma membrane,biological_process
88019,GO:0140208,Any apoptotic process that occurs as a result of mitochondrial fragmentation.,apoptotic process in response to mitochondrial fragmentation,biological_process
88020,GO:0140209,"The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum.",zinc ion import into endoplasmic reticulum,biological_process
88021,GO:0140210,Any process in which a protein is transported to the kinetochore along a microtubule.,protein transport along microtubule to kinetochore,biological_process
88022,GO:0140211,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid.",folic acid:proton symporter activity,molecular_function
88023,GO:0140212,"Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell.",regulation of long-chain fatty acid import into cell,biological_process
88024,GO:0140213,"Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell.",negative regulation of long-chain fatty acid import into cell,biological_process
88025,GO:0140214,"Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell.",positive regulation of long-chain fatty acid import into cell,biological_process
88026,GO:0140215,"Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.",regulation of D-aspartate import across plasma membrane,biological_process
88027,GO:0140216,"Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.",negative regulation of D-aspartate import across plasma membrane,biological_process
88028,GO:0140217,"Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.",positive regulation of D-aspartate import across plasma membrane,biological_process
88029,GO:0140218,Catalysis of the reaction: 2-methylpropenoyl-CoA + L-lysyl-[protein] = N6-methacrylyl-L-lysyl-[protein] + CoA + H+. Methacryl-CoA is a synonym of 2-methylpropenoyl-CoA.,histone methacryltransferase activity,molecular_function
88030,GO:0140219,Catalysis of the reaction: N6-methacrylyl-L-lysyl-[histone] + H2O = 2-methylprop-2-enoate + L-lysyl-[histone].,histone methacryllysine demethacrylase activity,molecular_function
88031,GO:0140220,"A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides.",pathogen-containing vacuole,cellular_component
88032,GO:0140221,Host-derived membrane of a pathogen-containing vacuole.,pathogen-containing vacuole membrane,cellular_component
88033,GO:0140222,The enclosed volume within the sealed membrane of a pathogen-containing vacuole.,pathogen-containing vacuole lumen,cellular_component
88034,GO:0140223,"A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact su...",general transcription initiation factor activity,molecular_function
88035,GO:0140224,A protein complex that regulates Arp2/3 complex-mediated actin nucleation.,SLAC complex,cellular_component
88036,GO:0140225,A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities.,DNA topoisomerase III-beta-TDRD3 complex,cellular_component
88037,GO:0140226,"Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA.",RNA topoisomerase activity,molecular_function
88038,GO:0140227,"The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.",serotonin-gated cation-selective signaling pathway,biological_process
88039,GO:0140228,Catalysis of the reaction: N(6)-benzoyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-benzoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].,histone benzoyllysine debenzoylase activity,molecular_function
88040,GO:0140229,Catalysis of the reaction: N(6)-isonicotinyl-L-lysyl-[protein] + H2O = isonicotinate + L-lysyl-[protein].,histone isonicotinyllysine deisonicotinylase activity,molecular_function
88041,GO:0140230,Catalysis of the reaction: isonicotinyl-CoA + histone = coA + N(6)-isonicotinyl-histone.,histone isonicotinyltransferase activity,molecular_function
88042,GO:0140231,The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons.,anterograde axonal transport of neurotransmitter receptor complex,biological_process
88043,GO:0140234,Catalysis of the transfer of a ubiquitin molecule to histone 3 at the lysine-23 residue.,histone H3K23 ubiquitin ligase activity,molecular_function
88044,GO:0140235,A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.,RNA polyadenylation at postsynapse,biological_process
88045,GO:0140236,Translation that occurs at the presynapse.,translation at presynapse,biological_process
88046,GO:0140237,"Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.","translation at presynapse, modulating chemical synaptic transmission",biological_process
88047,GO:0140238,A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.,presynaptic endocytosis,biological_process
88048,GO:0140239,A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.,postsynaptic endocytosis,biological_process
88049,GO:0140240,A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus.,perforant pathway to dendrate granule cell synapse,cellular_component
88050,GO:0140241,Translation that occurs at the synapse.,translation at synapse,biological_process
88051,GO:0140242,Translation that occurs at the postsynapse.,translation at postsynapse,biological_process
88052,GO:0140243,Any process that regulates translation occurring at the synapse.,regulation of translation at synapse,biological_process
88053,GO:0140244,Any process that regulates translation occurring at the presynapse.,regulation of translation at presynapse,biological_process
88054,GO:0140245,Any process that regulates translation occurring at the postsynapse.,regulation of translation at postsynapse,biological_process
88055,GO:0140246,The chemical reactions and pathways resulting in the breakdown of a protein at a synapse.,protein catabolic process at synapse,biological_process
88056,GO:0140247,The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.,protein catabolic process at presynapse,biological_process
88057,GO:0140248,Catalysis of the transfer of a ubiquitin molecule to histone 3 at the lysine-18 residue.,histone H3K18 ubiquitin ligase activity,molecular_function
88058,GO:0140249,The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.,protein catabolic process at postsynapse,biological_process
88059,GO:0140250,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.",regulation protein catabolic process at synapse,biological_process
88060,GO:0140251,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.",regulation protein catabolic process at presynapse,biological_process
88061,GO:0140252,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse.",regulation protein catabolic process at postsynapse,biological_process
88062,GO:0140253,"A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.",cell-cell fusion,biological_process
88063,GO:0140254,A histone reader that recognizes a histone H3 ubiquitinated at lysine 18.,histone H3K18ub reader activity,molecular_function
88064,GO:0140255,"Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation.",regulation of cellular response to phosphate starvation,biological_process
88065,GO:0140256,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation.",negative regulation of cellular response to phosphate starvation,biological_process
88066,GO:0140257,A histone reader that recognizes a histone H3 ubiquitinated at lysine 23.,histone H3K23ub reader activity,molecular_function
88067,GO:0140258,A histone reader that recognizes a histone H3 ubiquitinated at lysine 14.,histone H3K14ub reader activity,molecular_function
88068,GO:0140259,Binding to a PRC1 complex.,PRC1 complex binding,molecular_function
88069,GO:0140260,Binding to a mitochondrial proton-transporting ATP synthase complex.,mitochondrial proton-transporting ATP synthase complex binding,molecular_function
88070,GO:0140261,"A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10.",BCOR complex,cellular_component
88071,GO:0140262,Binding to a mRNA cap binding complex.,mRNA cap binding complex binding,molecular_function
88072,GO:0140263,"The chemical reactions and pathways resulting in the formation of keratan sulfate I (KS-I), N-linked via a GlcNAc attached to an asparigine residue in the target protein.",keratan sulfate-I proteoglycan biosynthetic process,biological_process
88073,GO:0140264,"The chemical reactions and pathways resulting in the formation of keratan sulfate II (KS-II), O-linked via a GalNAc attached to a serine or a threonine residue in the target protein.",keratan sulfate-II proteoglycan biosynthetic process,biological_process
88074,GO:0140265,"The chemical reactions and pathways resulting in the formation of keratan sulfate III (KS-III), O-linked via a mannose attached to a serine or a threonine residue in the target protein.",keratan sulfate-III proteoglycan biosynthetic process,biological_process
88075,GO:0140266,Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes.,Woronin body,cellular_component
88076,GO:0140267,"The entry of a symbiont into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration symbiont protein. This process mediates the entry of some non-enveloped virus into host cells, and results in the release of the virus contents into the host cell cytoplasm.",symbiont entry into host cell via permeabilization of host membrane,biological_process
88077,GO:0140268,"A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.",endoplasmic reticulum-plasma membrane contact site,cellular_component
88078,GO:0140269,"The chemical reactions and pathways resulting in the formation of arthro-series glucosylceramides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,4-GlcNAc-beta-1,3-Man-beta-1,4Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units.",arthro-series glucosylceramide biosynthetic process,biological_process
88079,GO:0140270,"The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol.",gluconate import across plasma membrane,biological_process
88080,GO:0140271,"The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.",hexose import across plasma membrane,biological_process
88081,GO:0140272,"Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein.",exogenous protein binding,molecular_function
88082,GO:0140273,The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected.,repair of mitotic kinetochore microtubule attachment defect,biological_process
88083,GO:0140274,The cell cycle process where kinetochore microtubule attachment defects are corrected.,repair of kinetochore microtubule attachment defect,biological_process
88084,GO:0140275,"A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1.",MIB complex,cellular_component
88085,GO:0140277,"The trimming, in the ER, of the protein newly attached N-glycan by glucosidases and mannosidases to produce high mannose-type N-glycans.",endoplasmic reticulum N-glycan trimming,biological_process
88086,GO:0140278,The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.,mitotic division septum assembly,biological_process
88087,GO:0140279,"Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",regulation of mitotic division septum assembly,biological_process
88088,GO:0140280,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",negative regulation of mitotic division septum assembly,biological_process
88089,GO:0140281,"Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.",positive regulation of mitotic division septum assembly,biological_process
88090,GO:0140282,"Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate.",carbon-nitrogen ligase activity on lipid II,molecular_function
88091,GO:0140283,"A protein complex that mediates transcriptional silencing of mobile genetic elements, such as retroviruses and transposable elements. In human, it is composed of TASOR, PPHLN1 and MPHOSPH8.",HUSH complex,cellular_component
88092,GO:0140284,A contact site between the endoplasmic reticulum membrane and the endosome membrane.,endoplasmic reticulum-endosome membrane contact site,cellular_component
88093,GO:0140285,The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.,endosome fission,biological_process
88094,GO:0140286,"A protein complex that mediates transcriptional silencing of interferon-stimulated genes. In human, it is composed of TASOR2, PPHLN1 and MPHOSPH8.",HUSH2 complex,cellular_component
88095,GO:0140287,Catalysis of the reaction: hydrazine + 4 Fe(III)-[cytochrome c] = N2 + 4 Fe(II)-[cytochrome c] + 4 H+.,hydrazine dehydrogenase activity,molecular_function
88096,GO:0140288,"A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM.",GBAF complex,cellular_component
88097,GO:0140290,The removal of ADP-ribose from ADP-ribosylserine.,peptidyl-serine ADP-deribosylation,biological_process
88098,GO:0140291,The removal of ADP-ribose from ADP-ribosylglutamate.,peptidyl-glutamate ADP-deribosylation,biological_process
88099,GO:0140292,Catalysis of the reaction: O-(ADP-D-ribosyl)-L-seryl-[protein] + H2O = ADP-D-ribose + L-seryl-[protein].,ADP-ribosylserine-[protein] hydrolase activity,molecular_function
88100,GO:0140293,Catalysis of the reaction: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-D-ribose + H+.,ADP-ribosylglutamate-[protein] hydrolase activity,molecular_function
88101,GO:0140294,Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.,NAD DNA ADP-ribosyltransferase activity,molecular_function
88102,GO:0140295,The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity.,pathogen-derived receptor ligand activity,molecular_function
88103,GO:0140296,"Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation.",general transcription initiation factor binding,molecular_function
88104,GO:0140297,"Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.",DNA-binding transcription factor binding,molecular_function
88105,GO:0140298,"Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis.",endocytic iron import into cell,biological_process
88106,GO:0140299,Binding to a molecule and eliciting a change in the protein's activity in response to the intracellular level of that molecule.,molecular sensor activity,molecular_function
88107,GO:0140300,The process in which serine is transported from the cytosol into the mitochondrial matrix.,serine import into mitochondrion,biological_process
88108,GO:0140301,The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae.,pollen-stigma interaction,biological_process
88109,GO:0140302,The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte.,pollen-style interaction,biological_process
88110,GO:0140303,Enables the transport of a lipid from a region of a membrane to a different region on the same membrane.,intramembrane lipid carrier activity,molecular_function
88111,GO:0140304,Catalysis of the reaction: hydrazine + 3 Fe(III)-[cytochrome c] + H2O = nitric oxide + 3 Fe(II)-[cytochrome c] + NH4+ + 2 H+.,hydrazine synthase activity,molecular_function
88112,GO:0140305,Catalysis of the reaction: hydroxylamine + 4 Fe(III)-[cytochrome c] + H2O = 4 Fe(II)-[cytochrome c] + nitrite + 5 H+.,hydroxylamine dehydrogenase activity,molecular_function
88113,GO:0140306,"The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex.",lipoprotein releasing activity,molecular_function
88114,GO:0140307,"A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by an N-formyl peptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. chemotaxis. N-formyl peptides include N-formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe), an N-formylated tripeptide sometimes simply referred to as chemotactic peptide. fMLF is a potent polymorphonuclear leukocyte (PMN) chemotactic facto...",phospholipase C-activating N-formyl peptide-activated signaling pathway,biological_process
88115,GO:0140308,"A plasma membrane-localized protein complex that binds insulin-like growth factors (IGF1 or IGF2). This class includes both signaling receptor complexes, such as the insulin-like growth factor 1 receptor (IGF1R) complex, which possesses intrinsic tyrosine kinase activity and initiates intracellular signaling cascades upon ligand binding, and non-signaling receptor complexes such as the insulin-like growth factor 2 receptor (IGF2R), which functions to sequester IGF2 and regulate its bioavailab...",insulin-like growth factor binding receptor complex,cellular_component
88116,GO:0140309,A protein carrier activity that binds to a protein in an unfolded state and escorts it to an acceptor molecule or to a specific location. The unfolded protein carrier prevents aggregation of the target protein while its being delivers to its final destination.,unfolded protein holdase activity,molecular_function
88117,GO:0140310,"Any process that increases the rate, frequency, or extent of peptidoglycan biosynthetic process.",positive regulation of peptidoglycan biosynthetic process,biological_process
88118,GO:0140311,Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,protein sequestering activity,molecular_function
88119,GO:0140312,"Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.",cargo adaptor activity,molecular_function
88120,GO:0140313,Binding to a specific molecule to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,molecular sequestering activity,molecular_function
88121,GO:0140314,Binding to a calcium ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,calcium ion sequestering activity,molecular_function
88122,GO:0140315,Binding to an iron ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,iron ion sequestering activity,molecular_function
88123,GO:0140317,The directed movement of a substance across the outer membrane in cells with two membranes.,export across cell outer membrane,biological_process
88124,GO:0140318,Directly binding to a specific protein and delivering it to a specific cellular location.,protein transporter activity,molecular_function
88125,GO:0140319,Binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor.,receptor decoy activity,molecular_function
88126,GO:0140320,Binding and sequestering PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response.,PAMP receptor decoy activity,molecular_function
88127,GO:0140321,A process in which a symbiont inhibits or disrupts the normal execution of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host autophagy,biological_process
88128,GO:0140322,A glycerophospholipase activity that cleaves the fatty acid attached to the sn-1 position of the glycerol group of a glycerophospholipid.,A1-type glycerophospholipase activity,molecular_function
88129,GO:0140324,Hydrolysis of a lysoglycerophospholipid at the first phosphodiester bond between the phosphate and glycerol.,lysophospholipase C activity,molecular_function
88130,GO:0140325,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex.",negative regulation of protein localization to medial cortex,biological_process
88131,GO:0140326,"Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.",ATPase-coupled intramembrane lipid carrier activity,molecular_function
88132,GO:0140327,"Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",flippase activity,molecular_function
88133,GO:0140328,"Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",floppase activity,molecular_function
88134,GO:0140329,The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.,lysophospholipid translocation,biological_process
88135,GO:0140330,A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane.,xenobiotic detoxification by transmembrane export across the cell outer membrane,biological_process
88136,GO:0140331,The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.,aminophospholipid translocation,biological_process
88137,GO:0140332,"Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.",lipopolysaccharide transfer activity,molecular_function
88138,GO:0140333,"Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",glycerophospholipid flippase activity,molecular_function
88139,GO:0140334,A process in which a lipopolysaccharide is transported to the cell outer membrane.,lipopolysaccharide localization to cell outer membrane,biological_process
88140,GO:0140335,"Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol, by cleavage of the  first phosphodiester bond between the phosphate and glycerol.",GPI anchor phospholipase C activity,molecular_function
88141,GO:0140336,"Catalysis of the reaction: a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H+.",glycosylphosphatidylinositol phospholipase D activity,molecular_function
88142,GO:0140337,Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location.,diacylglyceride transfer activity,molecular_function
88143,GO:0140338,"Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.",sphingomyelin transfer activity,molecular_function
88144,GO:0140339,Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location.,phosphatidylglycerol transfer activity,molecular_function
88145,GO:0140340,Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location.,cerebroside transfer activity,molecular_function
88146,GO:0140341,"Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylethanolamine floppase activity,molecular_function
88147,GO:0140342,A process in which an organism alters or subverts the heart contractility in another organism via the action of a venom.,venom-mediated perturbation of heart contraction,biological_process
88148,GO:0140343,"Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.",phosphatidylserine transfer activity,molecular_function
88149,GO:0140344,Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location.,triglyceride transfer activity,molecular_function
88150,GO:0140345,"Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylcholine flippase activity,molecular_function
88151,GO:0140346,"Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",phosphatidylserine flippase activity,molecular_function
88152,GO:0140347,"Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",N-retinylidene-phosphatidylethanolamine flippase activity,molecular_function
88153,GO:0140348,"Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",lysophosphatidylcholine flippase activity,molecular_function
88154,GO:0140349,"A supramolecular network that forms mainly through linkages of the short laminin arms between the N-terminal regions of one alpha, one beta, and one gamma chain. The laminin network associates with the collagen network to create the stable, sheet-like structure of the basement membrane ECM.",laminin network,cellular_component
88155,GO:0140350,"A type of amoeboid cell migration involving minimal contact between the cell and the surface, with the cell body standing upright and twisting, followed by rapid reattachment for directed movement.",inchworm-type cell migration,biological_process
88156,GO:0140351,"Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.",glycosylceramide flippase activity,molecular_function
88157,GO:0140352,"The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.",export from cell,biological_process
88158,GO:0140353,"The directed movement of a lipid from a cell, into the extracellular region.",lipid export from cell,biological_process
88159,GO:0140354,The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.,lipid import into cell,biological_process
88160,GO:0140355,The activity of a gene product that interacts with a cargo receptor and initiates endocytosis.,cargo receptor ligand activity,molecular_function
88161,GO:0140356,Catalysis of the reaction: L-lyxonate =2-dehydro-3-deoxy-L-arabinonate + H2O.,L-lyxonate dehydratase activity,molecular_function
88162,GO:0140357,The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol.,heme export from vacuole to cytoplasm,biological_process
88163,GO:0140358,"Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and Pi, the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.",P-type transmembrane transporter activity,molecular_function
88164,GO:0140359,Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.,ABC-type transporter activity,molecular_function
88165,GO:0140360,Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other.,cyclic-GMP-AMP transmembrane transporter activity,molecular_function
88166,GO:0140361,"The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol.",cyclic-GMP-AMP transmembrane import across plasma membrane,biological_process
88167,GO:0140363,"A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER).",TIS granule,cellular_component
88168,GO:0140364,"A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs.",GW body,cellular_component
88169,GO:0140365,"A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules.",RNP body,cellular_component
88170,GO:0140366,"A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids.",galectin lattice,cellular_component
88171,GO:0140367,An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.,antibacterial innate immune response,biological_process
88172,GO:0140368,"A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound.",decoy receptor complex,cellular_component
88173,GO:0140369,"A protein binding activity that stimulates and stabilizes the binding of a DNA binding transcription factor to its genomic DNA target, without directly interacting with DNA itself.",dbTF DNA binding stabilizer activity,molecular_function
88174,GO:0140370,A heterodimeric receptor for the cytokine LIF (leukemia inhibitory factor). In humans the receptor complex is made up of the gene products gp130 and LIFR.,type II oncostatin-M receptor complex,cellular_component
88175,GO:0140371,"The chemical reactions and pathways resulting in the formation of ornithine lipids, any of a class of phosphorus-free bacterial membrane lipids with an L-ornithine-derived head group.",ornithine lipid biosynthetic process,biological_process
88176,GO:0140374,A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.,antiviral innate immune response,biological_process
88177,GO:0140375,Receiving a signal and transmitting it in a cell to initiate an immune response.,immune receptor activity,molecular_function
88178,GO:0140376,Receiving a signal and transmitting it in a cell to initiate an innate immune response.,innate immune receptor activity,molecular_function
88179,GO:0140377,"The chemical reactions and pathways resulting in the formation of sophorolipid, a class of glycolipids containing a 2-O-beta-D-glucopyranosyl-D-glucopyranose (sophorose) unit covalently linked to the hydroxyl of a omega-hydroxy long chain fatty acids or (omega-1)-hydroxy long chain fatty acids.",sophorolipid biosynthetic process,biological_process
88180,GO:0140378,A structural molecule activity of a protein-containing complex component that serves to hold the complex together. Protein complex scaffolds are integral members of complexes.,protein complex scaffold activity,molecular_function
88181,GO:0140379,"Catalysis of the transfer of an acyl group to an acceptor group on a free amino acid, usually using acetyl-CoA as donor.",amino acid acyltransferase activity,molecular_function
88182,GO:0140380,"The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product.",psilocybin biosynthetic process,biological_process
88183,GO:0140381,Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) = 2 S-adenosyl-L-homocysteine + psilocybin.,4-hydroxytryptamine 4-phosphate methyltransferase activity,molecular_function
88184,GO:0140382,Catalysis of the reaction: tryptamine + reduced acceptor + O2 = 4-hydroxytryptamine + acceptor + H2O.,tryptamine 4-monooxygenase activity,molecular_function
88185,GO:0140383,Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H+.,4-hydroxytryptamine kinase activity,molecular_function
88186,GO:0140384,"The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania.",metacyclogenesis,biological_process
88187,GO:0140385,"Transfer of an amino group from an amino acid to an acceptor, usually a 2-oxo acid.",amino acid transaminase activity,molecular_function
88188,GO:0140386,"Catalysis of the reaction: cytidine(4) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA + S-adenosyl-L-homocysteine + H+. Acts on  cytidine(4) on tRNAPro and tRNAGly(GCC), and on adenosine(4) in tRNAHis.",tRNA (cytidine(4)/adenine(4)-2'-O-ribose)-methyltransferase activity,molecular_function
88189,GO:0140387,"Any process that stops, prevents, or reduces the frequency, rate or extent of L-glutamate biosynthetic process.",negative regulation of L-glutamate biosynthetic process,biological_process
88190,GO:0140388,Binding to the exposed unfolded portion of a polypeptide as it emerges from a membrane translocation channel/pore to drive its unidirectional transport across a membrane. Iterative cycles of ATP-dependent binding/rebinding by the chaperone prevents back sliding and drive vectorial transport.,protein translocation chaperone activity,molecular_function
88191,GO:0140389,"A signaling receptor complex that combines with a pathogen-associated molecular pattern (PAMP), a structure conserved among pathogenic organisms, to initiate an innate immune response.",pattern recognition receptor complex,cellular_component
88192,GO:0140390,"Any process that increases the rate, frequency, or extent of acetyl-CoA biosynthetic process.",positive regulation of acetyl-CoA biosynthesis,biological_process
88193,GO:0140391,"Any process that stops, prevents or reduces the frequency, rate or extent of acetyl-CoA biosynthetic process.",negative regulation of acetyl-CoA biosynthesis,biological_process
88194,GO:0140392,"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together outside a cell.",extracellular protein-containing complex,cellular_component
88195,GO:0140393,Catalysis of the reaction: (1'S)-averantin + NADP+ = norsolorinic acid + NADPH.,norsolorinic acid ketoreductase activity,molecular_function
88196,GO:0140394,"Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out).",ABC-type azole transporter activity,molecular_function
88197,GO:0140395,"Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O2 = (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H2O. Involved in aflatoxin biosynthesis.",averantin hydroxylase activity,molecular_function
88198,GO:0140396,"Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD+ = 5'-oxoaverantin + NADH.",5'-hydroxyaverantin dehydrogenase activity,molecular_function
88199,GO:0140397,"Catalyzes the reactions: versiconal hemiacetal acetate + H2O = versiconal + acetate, as well as versiconol acetate + H2O = versiconol + acetate.",versiconal hemiacetal acetate esterase activity,molecular_function
88200,GO:0140398,Catalyzes the reaction: versicolorin B + NADPH + O2 = versicolorin A + NADP+ + 2 H2O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.,versicolorin B desaturase activity,molecular_function
88201,GO:0140399,Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O2 = aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H2O + methanol + CO2. Produces both aflatoxin B(1) and aflatoxin B(2).,aflatoxin B synthase activity,molecular_function
88202,GO:0140400,"A specialized, transient apical extracellular matrix (aECM) that overlays the apical surface of the embryonic epidermis in Caenorhabditis elegans. It is secreted just prior to the start of embryonic elongation and acts as a mechanical scaffold to maintain embryonic integrity, distribute actomyosin-dependent stress, and anchor developing muscles.",embryonic sheath,cellular_component
88203,GO:0140401,Catalysis of the reaction: 4-phospho-D-erythronate + H2O = D-erythronate + phosphate.,4-phosphoerythronate phosphatase activity,molecular_function
88204,GO:0140402,The process in which an organism effects a change that impairs the structure or function of the stress granule of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. Stress granules are dynamic cytoplasmic condensates formed through liquid-liquid phase separation. They act as a critical hub for both cellular stress adaptation and defense against viruses.,symbiont-mediated disassembly of host stress granules,biological_process
88205,GO:0140403,A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated suppression of host innate immune response,biological_process
88206,GO:0140404,A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated perturbation of host innate immune response by symbiont,biological_process
88207,GO:0140405,A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase.,spindle pole body-led chromosome movement during mitotic interphase,biological_process
88208,GO:0140406,"The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region.",L-alanine export across the plasma membrane,biological_process
88209,GO:0140407,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out).,L-alanine:proton antiporter activity,molecular_function
88210,GO:0140408,"Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.",regulation of mRNA alternative polyadenylation,biological_process
88211,GO:0140409,"Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.",positive regulation of mRNA alternative polyadenylation,biological_process
88212,GO:0140410,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic cation(out) + HCO3-(out) = monoatomic cation(in) + HCO3-(in).,monoatomic cation:bicarbonate symporter activity,molecular_function
88213,GO:0140411,A process in which a symbiont inhibits or disrupts the normal assembly of stress granule of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. Stress granules are dynamic cytoplasmic condensates formed through liquid-liquid phase separation. They act as a critical hub for both cellular stress adaptation and defense against viruses.,symbiont-mediated suppression of host stress granule assembly,biological_process
88214,GO:0140412,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in).,zinc:bicarbonate symporter activity,molecular_function
88215,GO:0140413,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out).,zinc:bicarbonate:selenite symporter activity,molecular_function
88216,GO:0140414,Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.,phosphopantetheine-dependent carrier activity,molecular_function
88217,GO:0140415,A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated perturbation of host defenses by symbiont,biological_process
88218,GO:0140416,A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification.,transcription regulator inhibitor activity,molecular_function
88219,GO:0140417,Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts.,intracellularly ATP-gated calcium channel activity,molecular_function
88220,GO:0140418,A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated perturbation of host process by symbiont,biological_process
88221,GO:0140419,"A protein complex at least composed of PADI6, TLE6, NLRP14 and KHDC3 that forms fibrous structures in the mammalian ooplasm.",cytoplasmic lattice complex,cellular_component
88222,GO:0140420,The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.,heme import into cell,biological_process
88223,GO:0140421,The directed movement into cell of externally available heme by receptor-mediated endocytosis.,endocytic heme import into cell,biological_process
88224,GO:0140422,"A process by which a symbiont inhibits or disrupts thrombosis formation induced by host immune cells in response to a pathogenic symbiont. Microbial-associated molecular patterns (MAMPs) are recognized by host signaling receptors, leading to platelet activation. The blood clot formed creates a physical barrier that prevent symbiont dessimination, traps and kills pathogens.",symbiont-mediated suppression of host immunothrombosis,biological_process
88225,GO:0140423,A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants.,effector-mediated suppression of host pattern-triggered immunity signaling,biological_process
88226,GO:0140424,"A process in which a symbiont initiates, promotes, or enhances blood coagulation in another organism by activation of the intrinsic pathway. A common mechanism is the triggering the activity of host coagulation Factor XIIa (F12), one of the contact activation system (CAS) components, which consists of factor XII (FXII), prekallikrein (PK), and high molecular weight kininogen (HK). FXIIa instigates the coagulation cascade by cutting factor XI (FXI).","symbiont-mediated activation of blood coagulation, intrinsic pathway",biological_process
88227,GO:0140425,"The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol.",galactose import across plasma membrane,biological_process
88228,GO:0140426,"The series of molecular signals initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.",pathogen-associated molecular pattern receptor signaling pathway,biological_process
88229,GO:0140427,Catalysis of the reaction: (R)-carnitinyl-CoA = crotonobetainyl-CoA + H2O.,crotonobetainyl-CoA hydratase activity,molecular_function
88230,GO:0140428,A process in which an organism induces an immune response in another organism via the action of a venom.,venom-mediated perturbation of immune response,biological_process
88231,GO:0140429,"Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed.",positive regulation of mitotic sister chromatid biorientation,biological_process
88232,GO:0140430,"Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore.",positive regulation of chromosome passenger complex localization to kinetochore,biological_process
88233,GO:0140431,Binding to a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base.,DNA-(abasic site) binding,molecular_function
88234,GO:0140432,"Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-NpN-RNA + H20 = 5'OH-NpN + 5'P-RNA, where NpN represents a dinucleotide.",5'-hydroxyl dinucleotide hydrolase activity,molecular_function
88235,GO:0140433,"Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body.",regulation of protein localization to meiotic spindle pole body,biological_process
88236,GO:0140434,"Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body.",positive regulation of protein localization to meiotic spindle pole body,biological_process
88237,GO:0140435,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body.",negative regulation of protein localization to meiotic spindle pole body,biological_process
88238,GO:0140436,"Binding to a mitochondrial targeting sequence, a short stretch of amino acids found in a protein that acts as a signal to localize the protein to the mitochondrion.",mitochondrial signal sequence receptor activity,molecular_function
88239,GO:0140437,A process in which an organism alters or subverts the synaptic transmission in another organism via the action of a venom.,venom-mediated disruption of chemical synaptic transmission,biological_process
88240,GO:0140438,The covalent attachment of a stearoyl group to an amino acid in a protein.,protein stearoylation,biological_process
88241,GO:0140439,"Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein].",protein-cysteine S-stearoyltransferase activity,molecular_function
88242,GO:0140440,"Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein].",protein-cysteine S-oleoyltransferase activity,molecular_function
88243,GO:0140441,"Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].",protein-cysteine S-arachidonoyltransferase activity,molecular_function
88244,GO:0140442,Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.,peroxide sensor activity,molecular_function
88245,GO:0140443,"The binding activity of a molecule that brings together a mitochondrial outer membrane and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.",mitochondrion-plasma membrane adaptor activity,molecular_function
88246,GO:0140444,"The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.",cytoskeleton-nuclear membrane anchor activity,molecular_function
88247,GO:0140445,"A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop.","chromosome, telomeric repeat region",cellular_component
88248,GO:0140446,"The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.",fumigermin biosynthetic process,biological_process
88249,GO:0140447,"The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.",cytokine precursor processing,biological_process
88250,GO:0140448,"The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.",signaling receptor ligand precursor processing,biological_process
88251,GO:0140449,"The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.",centromere-nuclear envelope anchor activity,molecular_function
88252,GO:0140450,The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).,protein targeting to Golgi apparatus,biological_process
88253,GO:0140451,"A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum.",counting factor complex,cellular_component
88254,GO:0140452,A process in which an organism alters or subverts the synaptic transmission mediated by the neurotransmitter acetylcholine in another organism via the action of a venom.,venom-mediated perturbation of cholinergic synaptic transmission,biological_process
88255,GO:0140453,Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.,protein aggregate center,cellular_component
88256,GO:0140454,"The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.",protein aggregate center assembly,biological_process
88257,GO:0140455,"The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.",cytoplasm protein quality control,biological_process
88258,GO:0140456,The release of duplicated meiotic spindle pole bodies (SPBs).,initial meiotic spindle pole body separation,biological_process
88259,GO:0140457,Catalysis of the removal of a methyl group from a protein.,protein demethylase activity,molecular_function
88260,GO:0140459,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.",response to Gram-positive bacterium,biological_process
88261,GO:0140460,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium.",response to Gram-negative bacterium,biological_process
88262,GO:0140463,"An adaptor activity that brings together a protein and a region of the chromatin, such as a nucleosome, to establish or maintain the chromatin localization of the protein, or the complex to which it belongs.",chromatin-protein adaptor activity,molecular_function
88263,GO:0140464,The localization of silent mating-type cassette heterochromatin at a specific location in the nucleus.,subnuclear spatial organization of silent mating-type cassette heterochromatin,biological_process
88264,GO:0140465,A process in which an organism alters or subverts the synaptic transmission at the neuromuscular junction in another organism via the action of a venom.,venom-mediated disruption of neuromuscular synaptic transmission,biological_process
88265,GO:0140466,The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.,iron-sulfur cluster export from the mitochondrion,biological_process
88266,GO:0140467,"The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.",integrated stress response signaling,biological_process
88267,GO:0140468,"A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.",HRI-mediated signaling,biological_process
88268,GO:0140469,"A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.",GCN2-mediated signaling,biological_process
88269,GO:0140470,"A process in which a symbiont interferes with, inhibits or disrupt a toll-like receptor signaling pathway in the host organism by reducing the activity of host TRAF.",symbiont-mediated suppression of host toll-like receptor signaling pathway via inhibition of TRAF activity,biological_process
88270,GO:0140471,"Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.",positive regulation of transepithelial migration of symbiont in host,biological_process
88271,GO:0140472,The region directly beneath the plasma membrane at the cell tip at which no growth takes place.,cell cortex of non-growing cell tip,cellular_component
88272,GO:0140473,"The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.",telomere-nuclear envelope anchor activity,molecular_function
88273,GO:0140474,"The binding activity of a molecule that brings together a mitochondrial outer membrane and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.",mitochondrion-endoplasmic reticulum membrane tether activity,molecular_function
88274,GO:0140475,"The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.",spindle pole body anchor activity,molecular_function
88275,GO:0140476,"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host TRAF activity.",symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TRAF activity,biological_process
88276,GO:0140480,"A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane.",mitotic spindle pole body insertion into the nuclear envelope,biological_process
88277,GO:0140481,Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out).,ABC-type iron-sulfur cluster transporter activity,molecular_function
88278,GO:0140482,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron.",iron sensor activity,molecular_function
88279,GO:0140483,"The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.",kinetochore adaptor activity,molecular_function
88280,GO:0140484,"The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol.",5-aminolevulinic acid import across plasma membrane,biological_process
88281,GO:0140485,Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other.,5-aminolevulinic acid transmembrane transporter activity,molecular_function
88282,GO:0140486,Binding to a zinc ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,zinc ion sequestering activity,molecular_function
88283,GO:0140487,Binding to a metal ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,metal ion sequestering activity,molecular_function
88284,GO:0140488,Binding specifically to heme to deliver it to a transport vesicle.,heme receptor activity,molecular_function
88285,GO:0140489,"The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence.",molecular template activity,molecular_function
88286,GO:0140490,The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.,microtubule nucleator activity,molecular_function
88287,GO:0140492,An metal-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.,metal-dependent deubiquitinase activity,molecular_function
88288,GO:0140493,"A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when ...",very long-chain fatty acid beta-oxidation,biological_process
88289,GO:0140494,A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration.,migrasome,cellular_component
88290,GO:0140495,A cell migration-dependent mechanism for releasing cellular contents.,migracytosis,biological_process
88291,GO:0140496,Binding to a gamma-tubulin complex.,gamma-tubulin complex binding,molecular_function
88292,GO:0140497,"A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p.",mannan polymerase II complex,cellular_component
88293,GO:0140498,"A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p.",mannan polymerase I complex,cellular_component
88294,GO:0140499,"Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.",negative regulation of mitotic spindle assembly checkpoint signaling,biological_process
88295,GO:0140500,"Any process that modulates the frequency, rate or extent of reticulophagy.",regulation of reticulophagy,biological_process
88296,GO:0140501,"Any process that increases the frequency, rate or extent of reticulophagy.",positive regulation of reticulophagy,biological_process
88297,GO:0140502,A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signaling.,effector-mediated suppression of host salicylic acid-mediated innate immune signaling,biological_process
88298,GO:0140504,Degradation of a lipid droplet by microautophagy.,microlipophagy,biological_process
88299,GO:0140505,"Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion.",regulation of microlipophagy,biological_process
88300,GO:0140506,The binding activity of a molecule that brings together an ER membrane and an autophagosome membrane during reticulophagy.,endoplasmic reticulum-autophagosome adaptor activity,molecular_function
88301,GO:0140507,"The series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells.",granzyme-mediated programmed cell death signaling pathway,biological_process
88302,GO:0140509,"The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.",epithelium-like organization,biological_process
88303,GO:0140510,"A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei.",mitotic nuclear bridge,cellular_component
88304,GO:0140511,Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes.,mitotic nuclear bridge stalk,cellular_component
88305,GO:0140512,"The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei.",mitotic nuclear bridge midzone,cellular_component
88306,GO:0140513,"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.",nuclear protein-containing complex,cellular_component
88307,GO:0140515,"A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.",mitotic nuclear bridge organization,biological_process
88308,GO:0140516,The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.,mitotic nuclear pore complex disassembly,biological_process
88309,GO:0140517,"The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way.",protein-RNA adaptor activity,molecular_function
88310,GO:0140522,The activity of joining two lipid bilayers to form a single membrane.,fusogenic activity,molecular_function
88311,GO:0140523,A GTPase activity that mediates the joining of two lipid bilayers to form a single membrane.,GTPase-dependent fusogenic activity,molecular_function
88312,GO:0140525,"The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication.",antipodal site,cellular_component
88313,GO:0140526,A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.,double membrane vesicle viral factory assembly,biological_process
88314,GO:0140527,A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules.,reciprocal homologous recombination,biological_process
88315,GO:0140528,"The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).",bilobe structure assembly,biological_process
88316,GO:0140529,"The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes.",CMG complex assembly,biological_process
88317,GO:0140530,"The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading tak...",MCM complex loading,biological_process
88318,GO:0140533,A process by which a symbiont inhibits or disrupts the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host RNAi-mediated antiviral immune response,biological_process
88319,GO:0140534,A protein complex that is part of an endoplasmic reticulum.,endoplasmic reticulum protein-containing complex,cellular_component
88320,GO:0140535,A protein-containing complex located intracellularly.,intracellular protein-containing complex,cellular_component
88321,GO:0140537,A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.,transcription regulator activator activity,molecular_function
88322,GO:0140538,A process that prevents a zygote from fusing an additional cell.,negative regulation of conjugation with zygote,biological_process
88323,GO:0140539,"Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.",regulation of melanotic encapsulation of foreign target,biological_process
88324,GO:0140540,"Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.",negative regulation melanotic encapsulation of foreign target,biological_process
88325,GO:0140541,"The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.",piRNA transcription,biological_process
88326,GO:0140542,"Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.",regulation of piRNA transcription,biological_process
88327,GO:0140543,"Any process that increases the frequency, rate or extent of the synthesis of piRNA.",positive regulation of piRNA transcription,biological_process
88328,GO:0140544,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar.",septin collar organization,biological_process
88329,GO:0140545,An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.,ATP-dependent protein disaggregase activity,molecular_function
88330,GO:0140546,Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.,defense response to symbiont,biological_process
88331,GO:0140547,"The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.",acquisition of seed longevity,biological_process
88332,GO:0140549,The membrane surrounding the spore core (endospore core) that separates it from its external environment.,spore inner membrane,cellular_component
88333,GO:0140550,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate.","phosphatidylinositol-4,5-bisphosphate sensor activity",molecular_function
88334,GO:0140552,A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP.,TEAD-YAP complex,cellular_component
88335,GO:0140560,"Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.","xylosyl alpha-1,3-xylosyltransferase activity",molecular_function
88336,GO:0140561,Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine = UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine.,EGF-domain serine glucosyltransferase activity,molecular_function
88337,GO:0140562,Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine = UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.,EGF-domain serine xylosyltransferase activity,molecular_function
88338,GO:0140563,Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.,"UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity",molecular_function
88339,GO:0140566,"A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery.",histone reader activity,molecular_function
88340,GO:0140567,"The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.",membrane protein dislocase activity,molecular_function
88341,GO:0140568,The removal of a mislocalized protein from a cellular membrane.,extraction of mislocalized protein from membrane,biological_process
88342,GO:0140569,The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.,extraction of mislocalized protein from ER membrane,biological_process
88343,GO:0140570,The removal of a mislocalized protein from the mitochondrial outer membrane.,extraction of mislocalized protein from mitochondrial outer membrane,biological_process
88344,GO:0140571,Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.,transmembrane ascorbate ferrireductase activity,molecular_function
88345,GO:0140572,The division of a vacuole within a cell to form two or more separate vacuoles.,vacuole fission,biological_process
88346,GO:0140573,"A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.",histone H3-containing nucleosome,cellular_component
88347,GO:0140575,Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.,transmembrane monodehydroascorbate reductase activity,molecular_function
88348,GO:0140576,Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell.,ascorbate homeostasis,biological_process
88349,GO:0140580,The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome membrane during mitophagy.,mitochondrion autophagosome adaptor activity,molecular_function
88350,GO:0140581,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) = ADP + phosphate + Cu+(out).,P-type monovalent copper transporter activity,molecular_function
88351,GO:0140582,"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by extracellular cAMP binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.",adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway,biological_process
88352,GO:0140584,"A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis.",chromatin extrusion motor activity,molecular_function
88353,GO:0140585,"Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.",promoter-enhancer loop anchoring activity,molecular_function
88354,GO:0140586,"Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.",promoter-terminator loop anchoring activity,molecular_function
88355,GO:0140587,"Bridging together two DNA loop anchors together, maintaining a chromatin loop.",chromatin loop anchoring activity,molecular_function
88356,GO:0140588,"A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome.",chromatin looping,biological_process
88357,GO:0140590,A process mediated by a molecule secreted by a symbiont that results in the suppression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.,effector-mediated suppression of host defense response,biological_process
88358,GO:0140591,"The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm.",nuclear envelope budding,biological_process
88359,GO:0140592,Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to the arginine residue at position 8 of histone H3.,histone H3R8 methyltransferase activity,molecular_function
88360,GO:0140593,"The apoplast region surrounding a host plant cell. Plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. The host is defined as the larger of the organisms involved in a symbiotic interaction.",host apoplast,cellular_component
88361,GO:0140594,"Stops, prevents or reduces the activity of xyloglucan-specific endo-beta-1,4-glucanase.","xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity",molecular_function
88362,GO:0140595,"A protein complex located in the mitochondrial outer membrane that functions as an insertase, mediating the insertion of alpha-helical proteins from the cytosol into the outer membrane. Client proteins are usually single- and multi-span proteins that include components of the TOM complex.",MIM complex,cellular_component
88363,GO:0140596,A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. TOM transports beta-barrel precursors across the outer membrane and the sorting and assembly machinery (SAM complex) inserts them into the target membrane.,TOM complex,cellular_component
88364,GO:0140597,Directly binding to a protein and delivering it either to an acceptor molecule or to a specific location.,protein carrier activity,molecular_function
88365,GO:0140598,Binding to and carrying a lipoprotein between two different cellular locations by moving along with the target lipoprotein.,lipoprotein carrier activity,molecular_function
88366,GO:0140599,A nuclear membrane part at the midzone of the mitotic nuclear bridge. The midzone forms a bulge that is enriched in nuclear pores that lack baskets.,mitotic nuclear bridge midzone membrane domain,cellular_component
88367,GO:0140602,Inclusion bodies located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress or starvation.,nucleolar peripheral inclusion body,cellular_component
88368,GO:0140604,"The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA.",mycofactocin biosynthetic process,biological_process
88369,GO:0140605,A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella.,proton motive force-driven motor activity,molecular_function
88370,GO:0140608,Binds to and increases the activity of a cysteine-type endopeptidase.,cysteine-type endopeptidase activator activity,molecular_function
88371,GO:0140609,"The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA).",phycocyanobilin biosynthetic process,biological_process
88372,GO:0140610,Binding to a specific RNA molecule to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,RNA sequestering activity,molecular_function
88373,GO:0140612,"A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signaling response.",DNA damage sensor activity,molecular_function
88374,GO:0140613,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate.,P-type manganese transporter activity,molecular_function
88375,GO:0140614,The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin.,"1,8-dihydroxynaphthalene-melanin biosynthetic process",biological_process
88376,GO:0140615,A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA.,ATP-dependent citrate lyase complex,cellular_component
88377,GO:0140616,"Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.",iodotyrosine deiodinase activity,molecular_function
88378,GO:0140618,Catalysis of the reaction: 2 a Fe(II)-siderophore + NAD+ + H+ = 2 a Fe(III)-siderophore + NADH.,ferric-chelate reductase (NADH) activity,molecular_function
88379,GO:0140619,Binds to and increases a DNA strand exchange activity.,DNA strand exchange activator activity,molecular_function
88380,GO:0140620,"Binds to and stops, prevents or reduces a DNA strand exchange activity.",DNA strand exchange inhibitor activity,molecular_function
88381,GO:0140621,"A short filamentous structure on the surface of a bacterial cell distinguished from other pili by their D-mannose-sensitive agglutinatination of erythrocytes. In E. coli, type I pili consist of a short tip fibrillum made up of the adhesin protein (FimH) and two minor subunits (FimG and FimF) that is joined to the pilus rod, a homopolymer of ~1000 FimA subunits.",type I pilus,cellular_component
88382,GO:0140622,"Lipid transfer complex that is responsible for the non-vesicular transport of phospholipids, such as phosphatidylserine, from the endoplasmic reticulum to the endosome. It resides in the endosomal (acceptor) membrane and binds to specific lipids on the donor membrane at the ER-endosome contact site.",ER-to-endosome phospholipid transfer complex,cellular_component
88383,GO:0140623,The assembly from its constituent parts of a type I pilus.,type I pilus assembly,biological_process
88384,GO:0140624,"The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation.",EGAD pathway,biological_process
88385,GO:0140625,"Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.",opioid growth factor receptor activity,molecular_function
88386,GO:0140626,"The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A).",opioid growth factor receptor signaling pathway,biological_process
88387,GO:0140627,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytical...",ubiquitin-dependent protein catabolic process via the C-end degron rule pathway,biological_process
88388,GO:0140628,"Binds to and stops, prevents, or reduces the activity of an outwardly rectifying potassium channel.",outward rectifier potassium channel inhibitor activity,molecular_function
88389,GO:0140629,"Binds to and stops, prevents, or reduces the activity of a small conductance calcium-activated potassium channel.",small conductance calcium-activated potassium channel inhibitor activity,molecular_function
88390,GO:0140630,Catalysis of the reaction: 2 geranylgeranyl diphosphate = all-trans-phytoene + 2 diphosphate.,all-trans-phytoene synthase activity,molecular_function
88391,GO:0140631,"Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).",aldehyde dehydrogenase (NAD+) inhibitor activity,molecular_function
88392,GO:0140632,"The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.",canonical inflammasome complex assembly,biological_process
88393,GO:0140633,"The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex.",CARD8 inflammasome complex assembly,biological_process
88394,GO:0140634,An inflammasome complex that consists of CARD8 and CASP1.,CARD8 inflammasome complex,cellular_component
88395,GO:0140635,The movement of a neutrophil away from the site of wound or infection following its initial migration to the site.,neutrophil dispersal,biological_process
88396,GO:0140636,The process in which copper is transported from the cytosol into the mitochondrial matrix.,copper import into the mitochondrion,biological_process
88397,GO:0140638,"A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p.",small ribosomal subunit processing complex,cellular_component
88398,GO:0140639,"Any process that increases the frequency, rate or extent of a pyroptotic inflammatory response.",positive regulation of pyroptotic inflammatory response,biological_process
88399,GO:0140640,Catalytic activity that acts to modify a nucleic acid.,"catalytic activity, acting on a nucleic acid",molecular_function
88400,GO:0140641,The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase.,mitotic spindle formation (spindle phase two),biological_process
88401,GO:0140642,The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase.,meiotic spindle formation (spindle phase two),biological_process
88402,GO:0140643,Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.,hydroxymethylglutaryl-CoA reductase (NADH) activity,molecular_function
88403,GO:0140644,"Extracellular microbicidal structure composed of nuclear chromatin, histones and granular antimicrobial proteins. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms.",neutrophil extracellular trap,cellular_component
88404,GO:0140645,"The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens.",neutrophil extracellular trap formation,biological_process
88405,GO:0140646,"Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells.",negative regulation of pre-B cell receptor expression,biological_process
88406,GO:0140647,"A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.",P450-containing electron transport chain,biological_process
88407,GO:0140648,"Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.","positive regulation of cell cycle switching, mitotic to meiotic cell cycle",biological_process
88408,GO:0140649,"The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction.",symbiont-mediated cell-to-cell migration by invasive hypha,biological_process
88409,GO:0140650,The radial migration of a pyramidal neuron along radial glial cells.,radial glia-guided pyramidal neuron migration,biological_process
88410,GO:0140651,"The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.",futile creatine cycle,biological_process
88411,GO:0140652,The chemical reactions and pathways resulting in the formation of pyripyropene A.,pyripyropene A biosynthetic process,biological_process
88412,GO:0140654,The chemical reactions and pathways resulting in the formation of tryprostatin A.,tryprostatin A biosynthetic process,biological_process
88413,GO:0140656,Binds to and increases the activity of an endodeoxyribonuclease.,endodeoxyribonuclease activator activity,molecular_function
88414,GO:0140657,"A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.",ATP-dependent activity,molecular_function
88415,GO:0140658,"An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.",ATP-dependent chromatin remodeler activity,molecular_function
88416,GO:0140659,Binds to and modulates the activity of a motor protein.,cytoskeletal motor regulator activity,molecular_function
88417,GO:0140660,Binds to and increases the activity of a motor protein.,cytoskeletal motor activator activity,molecular_function
88418,GO:0140661,"Binds to and stops, prevents, or reduces the activity of a motor protein.",cytoskeletal motor inhibitor activity,molecular_function
88419,GO:0140662,"Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.",ATP-dependent protein folding chaperone,molecular_function
88420,GO:0140663,"Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.",ATP-dependent FeS chaperone activity,molecular_function
88421,GO:0140664,"A molecule that recognises toxic DNA structures, and initiates a signaling response, driven by ATP hydrolysis.",ATP-dependent DNA damage sensor activity,molecular_function
88422,GO:0140665,"A histone chaperone that carries a H3-H4 histone complex, driven by ATP hydrolysis.",ATP-dependent H3-H4 histone complex chaperone activity,molecular_function
88423,GO:0140666,An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.,annealing activity,molecular_function
88424,GO:0140667,"Any process that modulates the frequency, rate, or extent of production of oxytocin.",regulation of oxytocin production,biological_process
88425,GO:0140668,"Any process that activates or increases the frequency, rate or extent of production of oxytocin.",positive regulation of oxytocin production,biological_process
88426,GO:0140669,"Any process that stops, prevents, or reduces the rate of production of oxytocin.",negative regulation of oxytocin production,biological_process
88427,GO:0140670,Facilitating a conformational change to unload a cohesin complex from sister chromatids.,cohesin unloader activity,molecular_function
88428,GO:0140671,A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex.,ADA complex,cellular_component
88429,GO:0140672,"A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mi...",ATAC complex,cellular_component
88430,GO:0140673,"A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation.",transcription elongation-coupled chromatin remodeling,biological_process
88431,GO:0140674,"Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome, driven by ATP hydrolysis.",ATP-dependent histone chaperone activity,molecular_function
88432,GO:0140676,"Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate.",oscillatory cAMP signaling,biological_process
88433,GO:0140677,A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.,molecular function activator activity,molecular_function
88434,GO:0140678,A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.,molecular function inhibitor activity,molecular_function
88435,GO:0140679,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) = ADP + phosphate + Na(out).,ABC-type sodium transporter activity,molecular_function
88436,GO:0140680,Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K36me/H3K36me2 demethylase activity,molecular_function
88437,GO:0140681,Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K36me2/H3K36me3 demethylase activity,molecular_function
88438,GO:0140682,Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.,FAD-dependent H3K4me/H3K4me3 demethylase activity,molecular_function
88439,GO:0140683,Catalysis of the removal of a methyl group from a di or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K9me/H3K9me2 demethylase activity,molecular_function
88440,GO:0140684,Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3K9me2/H3K9me3 demethylase activity,molecular_function
88441,GO:0140685,Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.,FAD-dependent histone H3K9me/H3K9me2 demethylase activity,molecular_function
88442,GO:0140690,"A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT.",dihydropyrimidine dehydrogenase (NAD+) complex,cellular_component
88443,GO:0140691,Binding to an RNA or an RNA-containing complex to assist the folding process.,RNA folding chaperone,molecular_function
88444,GO:0140692,Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.,very long-chain fatty acid omega-hydroxylase activity,molecular_function
88445,GO:0140693,"Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate.",molecular condensate scaffold activity,molecular_function
88446,GO:0140694,"The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.",membraneless organelle assembly,biological_process
88447,GO:0140696,Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol.,(S)-2-hydroxyglutarate dehydrogenase (quinone) activity,molecular_function
88448,GO:0140698,The process in which physical connections are formed between sub-telomeric heterochromatin and the nuclear envelope facilitating bouquet formation.,attachment of telomeric heterochromatin to nuclear envelope,biological_process
88449,GO:0140699,Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.,cyclic GMP-AMP synthase activity,molecular_function
88450,GO:0140700,"Catalysis of the reaction: GTP + ATP = 3',2'-cGAMP + 2 diphosphate.","3',2'-cyclic GMP-AMP synthase activity",molecular_function
88451,GO:0140701,"Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP).","3',3'-cyclic GMP-AMP synthase activity",molecular_function
88452,GO:0140702,Binding to cyclic GMP-AMP (cGAMP) nucleotide.,cyclic GMP-AMP binding,molecular_function
88453,GO:0140703,"Binding to 3',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 3',5' linkages.","3',3'-cyclic GMP-AMP binding",molecular_function
88454,GO:0140704,"Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages.","3',2'-cyclic GMP-AMP binding",molecular_function
88455,GO:0140706,"A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite.",protein-containing complex localization to centriolar satellite,biological_process
88456,GO:0140707,"Binding to chromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization, or to enable equal segregation of the nuclear membrane during mitosis.",chromatin-nuclear membrane anchor activity,molecular_function
88457,GO:0140708,The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control system.,CAT tailing,biological_process
88458,GO:0140709,A type of non-canonical Wnt signaling in which Wnt binding to its receptor on the surface a the target cell results in internalization and cleavage of the frizzled receptor to yield a C-terminal fragment that is imported into the nucleus. The frizzled C-terminal fragment is incorporated into large ribonucleoprotein particles and stimulates their egress via nuclear budding.,Frizzled Nuclear Import pathway,biological_process
88459,GO:0140710,"Any process that modulates the frequency, rate or extent of a Frizzled Nuclear Import pathway.",regulation of Frizzled Nuclear Import pathway,biological_process
88460,GO:0140711,"Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway.",positive regulation of Frizzled Nuclear Import pathway,biological_process
88461,GO:0140712,"Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway.",negative regulation of Frizzled Nuclear Import pathway,biological_process
88462,GO:0140713,"Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome. The histone can be newly synthesized or result from nucleosome disassembly (either spontaneously, or by a histone chaperone).",histone chaperone activity,molecular_function
88463,GO:0140714,A protein complex that assists early maturation of nascent 60S ribosomal subunits. The complex interacts with the large ribosomal subunit rRNA via one of the components (Urb2 in S. cerevisiae) and requires a RNA helicase (Dbp6 in S. cerevisiae).,large ribosomal subunit pre-assembly complex,cellular_component
88464,GO:0140715,"A heterodimeric enzyme complex that catalyzes the ligation of serine to tRNA(Ser), forming L-seryl-tRNA(Ser).",serine-tRNA ligase complex,cellular_component
88465,GO:0140717,"Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.",entry into host through the stromata,biological_process
88466,GO:0140718,"The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27,...",facultative heterochromatin formation,biological_process
88467,GO:0140719,"The compaction of chromatin into heterochromatin, a conformation that is refractory to transcription and in that involves the methylation of histone H3K9. Constitutive heterochromatin cannot be converted back to euchromatin, the transcriptionally-active conformation.",constitutive heterochromatin formation,biological_process
88468,GO:0140720,"Heterochromatin that is located adjacent to the telomere, and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).",subtelomeric heterochromatin,cellular_component
88469,GO:0140721,Binds to and modulates the activity of a nuclease.,nuclease inhibitor activity,molecular_function
88470,GO:0140722,The chemical reactions and pathways resulting in the formation of mycophenolic acid (MPA). MPA is the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893.,mycophenolic acid biosynthetic process,biological_process
88471,GO:0140723,"The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria.",patulin biosynthetic process,biological_process
88472,GO:0140724,"Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of patulin.",positive regulation of patulin biosynthetic process,biological_process
88473,GO:0140725,Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme.,detoxification of free heme,biological_process
88474,GO:0140727,The formation of pericentric heterochromatin by a process mediated by a small interfering RNA (siRNA).,siRNA-mediated pericentric heterochromatin formation,biological_process
88475,GO:0140728,"Binding to a GC-box, a DNA motif with the consensus sequence GGGCGG that is located upstream of the start point of eukaryotic transcription units. The GC-box may occur in multiple copies or in either orientation relative to the transcription start site.",GC-box binding,molecular_function
88476,GO:0140729,"A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.",detoxification of endogenously produced metabolite,biological_process
88477,GO:0140730,"The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TA...",amphiregulin production,biological_process
88478,GO:0140731,"Any process that modulates the frequency, rate, or extent of production of amphiregulin.",regulation of amphiregulin production,biological_process
88479,GO:0140732,"Any process that activates or increases the frequency, rate or extent of production of amphiregulin.",positive regulation of amphiregulin production,biological_process
88480,GO:0140733,Binds to and increases the activity of a tRNA ligase.,tRNA ligase activator activity,molecular_function
88481,GO:0140734,The elimination of ammonium ions from an excretory cell.,ammonium excretion,biological_process
88482,GO:0140735,"The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR).",lovastatin biosynthetic process,biological_process
88483,GO:0140736,"Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin.",positive regulation of lovastatin biosynthetic process,biological_process
88484,GO:0140737,"Intracellular non-membrane bound organelle, consisting of proteinaceous polyhedral shells that encapsulate enzymes, protecting the contents from their surrounding milieu and/or the milieu from reactants in their interior. The self-assembling, 25-42 nm nanocompartment shell, unlike larger bacterial microcompartments, is made of only one protein, and has only a few proteins inside. Shells about vary from about 25-42 nm in diameter. The shell protein has an HK97-like fold and probably evolved fr...",encapsulin nanocompartment,cellular_component
88485,GO:0140738,"An inflammasome complex that consists of NLRP6, PYCARD/ASC and caspase-1 or caspase-4/caspase-11.",NLRP6 inflammasome complex,cellular_component
88486,GO:0140739,"The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex.",NLRP6 inflammasome complex assembly,biological_process
88487,GO:0140740,Catalysis of the reaction: L-arginyl-[protein] + NAD+ = ADP-riboxanated L-argininyl-[protein] + H+ + NH4+ + nicotinamide.,ADP-riboxanase-[protein] activity,molecular_function
88488,GO:0140741,Catalyzes the reaction: ATP + [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + uracil in tRNA + 2 reduced ferredoxin [iron-sulfur] cluster = AMP + diphosphate + 4-thiouracil in tRNA + [ThiI sulfur-carrier protein]-L-cysteine + 2 oxidized ferredoxin [iron-sulfur] cluster.,tRNA-uracil-4 sulfurtransferase activity,molecular_function
88489,GO:0140742,"The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template.",lncRNA transcription,biological_process
88490,GO:0140743,"Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA.",regulation of lncRNA transcription,biological_process
88491,GO:0140744,"Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA.",negative regulation of lncRNA transcription,biological_process
88492,GO:0140745,The transcription of a small interfering RNA from an RNA template.,siRNA transcription,biological_process
88493,GO:0140746,The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs).,siRNA catabolic process,biological_process
88494,GO:0140748,"Any process that activates or increases the frequency, rate or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process.",positive regulation of regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process,biological_process
88495,GO:0140749,Catalysis of the reaction: phlorizin + H2O = beta-D-glucose + phloretin.,phlorizin hydrolase activity,molecular_function
88496,GO:0140750,"A histone octamer slider activity that spaces nucleosomes along chromosomal DNA. This activity is involved in assembling chromatin in uniform nucleosome arrays to regulate transcription by RNA polymerases I, II, and III, as well as DNA replication, recombination and repair.",nucleosome array spacer activity,molecular_function
88497,GO:0140751,A chromatin remodeler activity that slides core histone octamers along chromosomal DNA.,histone octamer slider activity,molecular_function
88498,GO:0140752,Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a branched [(1->3)-beta-D-glucosyl](n+1).,"branched 1,3-beta-D-glucan synthase activity",molecular_function
88499,GO:0140753,Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a linear [(1->3)-beta-D-glucosyl](n+1).,"linear 1,3-beta-D-glucan synthase activity",molecular_function
88500,GO:0140754,"A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.",reorganization of cellular membranes to establish viral sites of replication,biological_process
88501,GO:0140755,"A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.",reorganization of host cellular membranes to establish sites of replication,biological_process
88502,GO:0140756,The action of a molecule that contributes to the structural integrity of the proteasome.,structural constituent of proteasome,molecular_function
88503,GO:0140757,An thiol-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.,cysteine-type deNEDDylase activity,molecular_function
88504,GO:0140758,An metal-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.,metal-dependent deNEDDylase activity,molecular_function
88505,GO:0140759,Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 56) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 56). This reaction is the addition of a methyl group to the lysine residue at position 56 of the histone H3 protein.,histone H3K56 methyltransferase activity,molecular_function
88506,GO:0140760,Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 56 of the histone H3 protein.,histone H3K56me2/H3K56me3 demethylase activity,molecular_function
88507,GO:0140761,"Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.","calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity",molecular_function
88508,GO:0140762,"Catalysis of the reaction: a quinone + D-glucose = a quinol + D-glucono-1,5-lactone.","glucose dehydrogenase (FAD, quinone) activity",molecular_function
88509,GO:0140763,"A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.",programmed DNA elimination by elimination of internal DNA segments,biological_process
88510,GO:0140764,A translational repressor activity that binds to a single-stranded small regulatory RNA (either a miRNA or a siRNA) to guide it to its target mRNA.,small RNA binding translational repressor activity,molecular_function
88511,GO:0140765,"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 56) + NAD+ + H2O = histone H3 L-lysine (position 56) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K56 to NAD, producing nicotinamide.","histone H3K56 deacetylase activity, NAD-dependent",molecular_function
88512,GO:0140766,"A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA tr...",siRNA-mediated post-transcriptional gene silencing,biological_process
88513,GO:0140767,"An adaptor that brings together an enzyme and its substrate. Adaptors recruit the substrate to its enzyme, thus contributing to substrate selection and specificity.",enzyme-substrate adaptor activity,molecular_function
88514,GO:0140768,An enzyme-substrate adaptor that bings together a protein ADP-ribosyl transferase and its substrate.,protein ADP-ribosyltransferase-substrate adaptor activity,molecular_function
88515,GO:0140769,Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein].,ACP-dependent peptidyl-lysine N6-myristoyltransferase activity,molecular_function
88516,GO:0140770,Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N(6)-tetradecanoyl-L-lysyl-[protein].,CoA-dependent peptidyl-lysine N6-myristoyltransferase activity,molecular_function
88517,GO:0140771,Catalysis of the reaction: hexadecanoyl-[ACP] + L-lysyl-[protein] = H+ + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein].,ACP-dependent peptidyl-lysine N6-palmitoyltransferase activity,molecular_function
88518,GO:0140772,Catalysis of the reaction: L-lysyl-[protein] + hexadecanoyl-CoA = CoA + H+ + N(6)-hexadecanoyl-L-lysyl-[protein].,CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity,molecular_function
88519,GO:0140773,Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein demyristoylase activity,molecular_function
88520,GO:0140774,Catalysis of the reaction: N6-octadecanoyl-L-lysyl-[protein] + NAD+ + H2O = octadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein depalmitoylase activity,molecular_function
88521,GO:0140775,Binding to an actin filament and promoting the dissociation of an actin filament branch.,actin filament debranching activity,molecular_function
88522,GO:0140776,"A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.",protein-containing complex destabilizing activity,molecular_function
88523,GO:0140777,"A molecular function that involves direct binding to one of the subunits of a protein-containing complex, thus preventing an interaction with a factor that would promote dissociation of the complex.",protein-containing complex stabilizing activity,molecular_function
88524,GO:0140778,A protein-containing complex stabilizing activity that prevents dissociation of microtubules.,microtubule stabilizing activity,molecular_function
88525,GO:0140779,"The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",XCL1 production,biological_process
88526,GO:0140781,"The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain.",ilicicolin H biosynthetic process,biological_process
88527,GO:0140782,"The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety.",novofumigatonin biosynthetic process,biological_process
88528,GO:0140783,"The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity.",(M)-viriditoxin biosynthetic process,biological_process
88529,GO:0140784,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of a metal ion.",metal ion sensor activity,molecular_function
88530,GO:0140785,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of an amino acid.",amino acid sensor activity,molecular_function
88531,GO:0140786,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of glutamine.",glutamine sensor activity,molecular_function
88532,GO:0140787,"Catalysis of the active transport of a phosphate ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",phosphate ion uniporter activity,molecular_function
88533,GO:0140788,"Catalysis of the active transport of a L-glutamate across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",L-glutamate uniporter activity,molecular_function
88534,GO:0140789,Catalysis of the reaction: a phosphorylated histone + H2O = a protein + phosphate.,histone phosphatase activity,molecular_function
88535,GO:0140791,Catalysis of the reaction: histone H2AX serine phosphate (position 139) + H2O = histone H2AX serine (position 139) + phosphate.,histone H2AXS139 phosphatase activity,molecular_function
88536,GO:0140793,Catalysis of the reaction: histone H2AX tyrosine phosphate (position 142) + H2O = histone H2AX tyrosine (position 142) + phosphate.,histone H2AXY142 phosphatase activity,molecular_function
88537,GO:0140794,"Catalysis of the reaction: H2O + histone 3 L-arginyl = histone 3 L-citrullyl + NH4+, resulting in histone citrullination.",histone arginine deiminase activity,molecular_function
88538,GO:0140795,"Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.",histone H3R2 arginine deiminase activity,molecular_function
88539,GO:0140796,"Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.",histone H3R8 arginine deiminase activity,molecular_function
88540,GO:0140797,"Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.",histone H3R17 arginine deiminase activity,molecular_function
88541,GO:0140798,"Catalysis of the reaction: H2O + histone H3 L-arginyl (position 26)= histone H3 L-citrullyl (position 26) + NH4+, resulting in histone H3 citrullination at position 26.",histone H3R26 arginine deiminase activity,molecular_function
88542,GO:0140799,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + H+(in) = glycine(in) + H+(out).,glycine:proton antiporter activity,molecular_function
88543,GO:0140800,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4-aminobutanoate(out) + H+(in) = 4-aminobutanoate(in) + H+(out).,gamma-aminobutyric acid:proton antiporter activity,molecular_function
88544,GO:0140801,Catalysis of the reaction: histone H2AX-tyrosine (position 142) + ATP = (histone H2AX-phosphotyrosine (position 142) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 142 of histone variant H2AX.,histone H2AXY142 kinase activity,molecular_function
88545,GO:0140802,Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide.,NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity,molecular_function
88546,GO:0140803,Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein].,NAD+-protein-cysteine ADP-ribosyltransferase activity,molecular_function
88547,GO:0140804,Catalysis of the reaction: L-lysyl-[protein] + NAD+ = H+ + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide.,NAD+-protein-lysine ADP-ribosyltransferase activity,molecular_function
88548,GO:0140805,Catalysis of the reaction: L-seryl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein].,NAD+-protein-serine ADP-ribosyltransferase activity,molecular_function
88549,GO:0140806,Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide.,NAD+-protein-aspartate ADP-ribosyltransferase activity,molecular_function
88550,GO:0140807,Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide.,NAD+-protein-glutamate ADP-ribosyltransferase activity,molecular_function
88551,GO:0140808,Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein].,NAD+-protein-tyrosine ADP-ribosyltransferase activity,molecular_function
88552,GO:0140809,"Catalysis of the reaction: H2O + histone H4 L-arginyl (position 3)= histone H4 L-citrullyl (position 3) + NH4+, resulting in histone H4 citrullination at position 3.",histone H4R3 arginine deiminase activity,molecular_function
88553,GO:0140810,"Catalysis of the reaction: H2O + histone H1 L-arginyl (position 54)= histone H1 L-citrullyl (position 54) + NH4+, resulting in histone H1 citrullination at position 54.",histone H1R54 arginine deiminase activity,molecular_function
88554,GO:0140811,"Catalysis of the reaction: H2O + histone 2A L-arginyl (position 3)= histone 2A L-citrullyl (position 3) + NH4+, resulting in histone H2A citrullination at position 3.",histone H2AR3 arginine deiminase activity,molecular_function
88555,GO:0140812,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: orotate(out) + anion (in) = orotate (in) + anion (out).,orotate:monoatomic anion antiporter activity,molecular_function
88556,GO:0140813,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urate(out) + anion (in) = urate (in) + anion (out).,urate:monoatomic anion antiporter activity,molecular_function
88557,GO:0140814,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + Na+(out) + Cl-(out)= glycine betaine(in) + Na+(in) + Cl-(in).,glycine betaine:sodium:chloride symporter activity,molecular_function
88558,GO:0140815,Catalysis of the reaction: L-histidyl-[protein] + NAD+ = H+ + Nt-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide.,NAD+-protein-histidine ADP-ribosyltransferase activity,molecular_function
88559,GO:0140816,Catalysis of the transfer of ADP-ribose groups to the serine-6 or an equivalent residue of the N-terminal tail of histone H2B.,NAD+-histone H2BS6 serine ADP-ribosyltransferase activity,molecular_function
88560,GO:0140817,Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3.,NAD+-histone H3S10 serine ADP-ribosyltransferase activity,molecular_function
88561,GO:0140818,A 5'-end triphospho-[mRNA] + H2O = a 5'-end diphospho-[mRNA] + H+ + phosphate.,mRNA 5'-triphosphate monophosphatase activity,molecular_function
88562,GO:0140819,Enables the transfer of UDP-beta-L-arabinofuranose from one side of a membrane to the other.,UDP-beta-L-arabinofuranose transporter activity,molecular_function
88563,GO:0140820,The directed movement of substances from the cytosol into the Golgi apparatus of a cell.,cytosol to Golgi apparatus transport,biological_process
88564,GO:0140821,The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell.,UDP-beta-L-arabinofuranose import into Golgi lumen,biological_process
88565,GO:0140822,Catalysis of the transfer of ADP-ribose groups to the glutamate-35 residue of the N-terminal tail of histone H2B (or an equivalent residue).,NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity,molecular_function
88566,GO:0140823,Catalysis of the reaction: histone H2B-serine (position 36) + ATP = histone H2B-phosphoserine (position 36) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 36 of histone H2B.,histone H2BS36 kinase activity,molecular_function
88567,GO:0140824,Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.,thioredoxin-dependent peroxiredoxin activity,molecular_function
88568,GO:0140825,Catalysis of the reaction: 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O.,lactoperoxidase activity,molecular_function
88569,GO:0140826,Enables the transfer of zinc from one side of a membrane to the other according to the reaction: H+(out) + Zn2+(in) = H+(in) + Zn2+(out).,zinc:proton antiporter activity,molecular_function
88570,GO:0140827,Binding to and delivering zinc ions to a target protein.,zinc chaperone activity,molecular_function
88571,GO:0140828,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(in) = solute(in) + Na+(out).,metal cation:monoatomic cation antiporter activity,molecular_function
88572,GO:0140829,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(in) + HCO3-(out) = solute(out) + HCO3-(in).,bicarbonate:monoatomic anion antiporter activity,molecular_function
88573,GO:0140830,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-glutamine(out) + Na+(out) = H+(out) + L-glutamine(in) + Na+(in).,"L-glutamine, sodium:proton antiporter activity",molecular_function
88574,GO:0140831,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-asparagine(out) + Na+(out) = H+(out) + L-asparagine(in) + Na+(in).,"L-asparagine, sodium:proton antiporter activity",molecular_function
88575,GO:0140832,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-histidine(out) + Na+(out) = H+(out) + L-histidine(in) + Na+(in).,"L-histidine, sodium:proton antiporter activity",molecular_function
88576,GO:0140833,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphotyrosine (position 1).,RNA polymerase II CTD heptapeptide repeat Y1 kinase activity,molecular_function
88577,GO:0140834,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 2).,RNA polymerase II CTD heptapeptide repeat S2 kinase activity,molecular_function
88578,GO:0140835,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphothreonine (position 4).,RNA polymerase II CTD heptapeptide repeat T4 kinase activity,molecular_function
88579,GO:0140836,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 5).,RNA polymerase II CTD heptapeptide repeat S5 kinase activity,molecular_function
88580,GO:0140837,Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 7).,RNA polymerase II CTD heptapeptide repeat S7 kinase activity,molecular_function
88581,GO:0140838,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) = RNA polymerase II large subunit trans-proline (omega=0).,RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity,molecular_function
88582,GO:0140839,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 3) = RNA polymerase II large subunit trans-proline (omega=0) (position 3).,RNA polymerase II CTD heptapeptide repeat P3 isomerase activity,molecular_function
88583,GO:0140840,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 6) = RNA polymerase II large subunit trans-proline (omega=0) (position 6).,RNA polymerase II CTD heptapeptide repeat P6 isomerase activity,molecular_function
88584,GO:0140841,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine.,RNA polymerase II C-terminal domain O-GlcNAc transferase activity,molecular_function
88585,GO:0140842,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5).,RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity,molecular_function
88586,GO:0140843,Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 7).,RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity,molecular_function
88587,GO:0140844,Catalysis of the transfer of ADP-ribose groups to the glutamate-2 residue of the N-terminal tail of histone H2B (or an equivalent residue).,NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity,molecular_function
88588,GO:0140845,"A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.",regulation of promoter clearance from RNA polymerase II promoter,biological_process
88589,GO:0140846,"A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.",positive regulation of promoter clearance from RNA polymerase II promoter,biological_process
88590,GO:0140847,"A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II.",negative regulation of promoter clearance from RNA polymerase II promoter,biological_process
88591,GO:0140848,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + monoatomic cation(in) = solute(in) + monoatomic cation(out). Monoatomic cations include H+, Mg2+, Ca2+, etc.",amino acid:monoatomic cation antiporter activity,molecular_function
88592,GO:0140849,"A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite.",ATP-dependent H2AZ histone chaperone activity,molecular_function
88593,GO:0140850,"Catalysis of the transfer of a ubiquitin molecule to a histone 2B at the conserved C-terminal lysine (K) residue. The last K residue is at position 119 in fission yeast, 123 in budding yeast, and 120 in mammals.",histone H2B C-terminal K residue ubiquitin ligase activity,molecular_function
88594,GO:0140851,Catalysis of the transfer of a ubiquitin molecule to histone 3 at the lysine-14 residue.,histone H3K14 ubiquitin ligase activity,molecular_function
88595,GO:0140852,Catalysis of the transfer of ubiquitin to a histone substrate.,histone ubiquitin ligase activity,molecular_function
88596,GO:0140853,Catalysis of the reaction: cholesterol + glycyl-L-cysteinyl-[protein] + H+ = [protein]-C-terminal glycyl cholesterol ester + N-terminal L-cysteinyl-[protein].,cholesterol-protein transferase activity,molecular_function
88597,GO:0140854,"The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-19-mediated signaling pathway,biological_process
88598,GO:0140855,Catalysis of the reaction: histone H3-serine (position 57) + ATP = histone H3-phosphoserine (position 57) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 57 of histone H3.,histone H3S57 kinase activity,molecular_function
88599,GO:0140856,Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-13 residue.,histone H2AK13 ubiquitin ligase activity,molecular_function
88600,GO:0140857,Catalysis of the reaction: histone H3-threonine (position 45) + ATP = histone H3-phosphothreonine (position 45) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 45 of histone H3.,histone H3T45 kinase activity,molecular_function
88601,GO:0140858,Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-15 residue.,histone H2AK15 ubiquitin ligase activity,molecular_function
88602,GO:0140859,"Catalysis of the reaction: H2O + medicarpin = 4'-methoxyisoflavan-2',4,7-triol.",pterocarpan synthase activity,molecular_function
88603,GO:0140860,"Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH.",(3R)-2'-hydroxyisoflavanone reductase (NADP+) activity,molecular_function
88604,GO:0140861,A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions.,DNA repair-dependent chromatin remodeling,biological_process
88605,GO:0140862,Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.,histone H2AK119 ubiquitin ligase activity,molecular_function
88606,GO:0140863,Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-127 residue.,histone H2AK127 ubiquitin ligase activity,molecular_function
88607,GO:0140864,Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-129 residue.,histone H2AK129 ubiquitin ligase activity,molecular_function
88608,GO:0140865,"The series of molecular signals initiated by interleukin-22 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-22-mediated signaling pathway,biological_process
88609,GO:0140866,"The series of molecular signals initiated by interleukin-20 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",interleukin-20-mediated signaling pathway,biological_process
88610,GO:0140869,"Stops, prevents or reduces the activity of miRNA-mediated gene silencing activity by base-pairing with a target miRNA. An example of this activity is mediated by long non-coding RNAs (lncRNAs).",miRNA inhibitor activity via base-pairing,molecular_function
88611,GO:0140870,"Binds to and stops, prevents or reduces the activity of RNA polymerase.",RNA polymerase inhibitor activity,molecular_function
88612,GO:0140871,"Binds to and stops, prevents or reduces the activity of an RNA polymerase inhibitor.",repressor of RNA polymerase inhibitor activity,molecular_function
88613,GO:0140872,"The chemical reactions and pathways resulting in the formation of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system.",viridicatumtoxin biosynthetic process,biological_process
88614,GO:0140873,"The chemical reactions and pathways resulting in the formation of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels.",paxilline biosynthetic process,biological_process
88615,GO:0140874,"The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture.",paraherquonin biosynthetic process,biological_process
88616,GO:0140875,"The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin.",PR-toxin biosynthetic process,biological_process
88617,GO:0140876,"The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity.",andrastin A biosynthetic process,biological_process
88618,GO:0140877,"The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase.",mevastatin biosynthetic process,biological_process
88619,GO:0140878,"The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections.",griseofulvin biosynthetic process,biological_process
88620,GO:0140879,"The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation.",conidiogenone biosynthetic process,biological_process
88621,GO:0140880,"The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities.",terrein biosynthetic process,biological_process
88622,GO:0140881,"Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of the fungal metabolite terrein.",positive regulation terrein biosynthetic process,biological_process
88623,GO:0140882,"The directed movement of zinc ions from a cell, into the extracellular region.",zinc export across plasma membrane,biological_process
88624,GO:0140883,"A process in which a symbiont initiates, promotes, or enhances the normal execution of host reticulophagy, leading to an increase in the frequency, rate or extent of reticulophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host reticulophagy,biological_process
88625,GO:0140884,"A process in which a symbiont interferes with, inhibits or disrupts a type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma.",symbiont-mediated suppression of host type II interferon-mediated signaling pathway,biological_process
88626,GO:0140885,"A process in which a symbiont interferes with, inhibits or disrupts a type III interferon-mediated signaling in the host organism. Type III interferon is also known as interferon-lambda.",symbiont-mediated suppression of host type III interferon-mediated signaling pathway,biological_process
88627,GO:0140886,"Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.",symbiont-mediated suppression of host interferon-mediated signaling pathway,biological_process
88628,GO:0140887,"Any process that activates or increases the frequency, rate or extent of the controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",positive regulation of nucleosome disassembly,biological_process
88629,GO:0140888,"The series of molecular signals initiated by type II interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type II interferon is also known as interferon-gamma.",interferon-mediated signaling pathway,biological_process
88630,GO:0140889,The disruption of nucleosomes during DNA replication to allow the replication machinery to access the DNA.,DNA replication-dependent chromatin disassembly,biological_process
88631,GO:0140890,A histone chaperone that carries a H1 histone.,H1 histone chaperone activity,molecular_function
88632,GO:0140891,A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA.,tRNA-derived regulatory ncRNA processing,biological_process
88633,GO:0140892,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction chloride(in) + 2 hydrogencarbonate(out) + Na+(out) = chloride(out) + 2 hydrogencarbonate(in) + Na+(in).,"sodium,bicarbonate:chloride antiporter activity",molecular_function
88634,GO:0140893,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + amino acid(out) + Na+(out) = H+(out) + amino acid(in) + Na+(in).,"neutral amino acid, sodium:proton antiporter activity",molecular_function
88635,GO:0140894,"The series of molecular signals initiated by a ligand binding to an endolysosomal pattern recognition receptor (PRR) of the toll-like family. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.",endolysosomal toll-like receptor signaling pathway,biological_process
88636,GO:0140895,The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR) of the toll-like family.,cell surface toll-like receptor signaling pathway,biological_process
88637,GO:0140896,"The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING.",cGAS/STING signaling pathway,biological_process
88638,GO:0140897,Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.,mechanoreceptor activity,molecular_function
88639,GO:0140898,A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation.,CENP-A eviction from euchromatin,biological_process
88640,GO:0140899,The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.,plastid gene expression,biological_process
88641,GO:0140900,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + HCO3-(out) = chloride(out) + HCO3-(in).,chloride:bicarbonate antiporter activity,molecular_function
88642,GO:0140901,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).,L-asparagine:sodium symporter activity,molecular_function
88643,GO:0140902,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + Na+(out) = L-glutamine(in) + Na+(in).,L-glutamine:sodium symporter activity,molecular_function
88644,GO:0140903,Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 26) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 26). This reaction is the addition of a methyl group to the arginine residue at position 26 of histone H3.,histone H3R26 methyltransferase activity,molecular_function
88645,GO:0140904,"A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes.",cytoophidium organization,biological_process
88646,GO:0140905,Catalysis of the reaction: R-CH + a halogen + H2O2 = R-C-halogen + H2O.,haloperoxidase activity,molecular_function
88647,GO:0140906,Catalysis of the reaction: R-CH + a halogen + oxygen donor = R-C-halogen +H2O.,halogenase activity,molecular_function
88648,GO:0140907,Catalysis of the reaction: R-CH + a halogen + FADH2 + O2 = R-C-halogen + FAD + H2O.,flavin-dependent halogenase activity,molecular_function
88649,GO:0140908,Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 122) = CoA + histone H3 N6-acetyl-L-lysine (position 122).,histone H3K122 acetyltransferase activity,molecular_function
88650,GO:0140909,"The process of doubling of the number of maxicircles and minicircles and distribution of the progeny into two daughter networks, which are identical to the parent kinetoplast DNA network.",kinetoplast DNA replication,biological_process
88651,GO:0140910,A complex consisting of ADAM17 in complex with regulatory iRhoms and FERM domain containing proteins.,iRhom2/ADAM17 sheddase complex,cellular_component
88652,GO:0140911,"An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death.",pore-forming activity,molecular_function
88653,GO:0140912,Binding to a membrane and increasing its permeability. This may lead to cell membrane lysis and cell content release.,membrane destabilizing activity,molecular_function
88654,GO:0140913,"The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.",viral release via disruption of host peptidoglycan cell wall,biological_process
88655,GO:0140914,"The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a secretory vesicle.",zinc ion import into secretory vesicle,biological_process
88656,GO:0140915,"The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule.",zinc ion import into zymogen granule,biological_process
88657,GO:0140916,"The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a lysosome.",zinc ion import into lysosome,biological_process
88658,GO:0140917,"The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion.",zinc ion import into mitochondrion,biological_process
88659,GO:0140918,"The core region of the centrosome, a layered structure containing proteins, surrounded by the centrosomal corona. The core duplicates once per cell cycle at the G2/M transition when two outer layers form the mitotic spindle poles.",centrosomal core,cellular_component
88660,GO:0140919,"The suite of morphological and architectural changes in an organism induced by high ambient temperatures, below the heat-stress range.",thermomorphogenesis,biological_process
88661,GO:0140920,"Any process that modulates the frequency, rate or extent of thermomorphogenesis.",regulation of thermomorphogenesis,biological_process
88662,GO:0140921,"Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis.",negative regulation of thermomorphogenesis,biological_process
88663,GO:0140922,"Any process that increases the rate, frequency or extent of thermomorphogenesis.",positive regulation of thermomorphogenesis,biological_process
88664,GO:0140923,"The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB).",magnetosome assembly,biological_process
88665,GO:0140924,The directed movement of L-kynurenine across a membrane.,L-kynurenine transmembrane transport,biological_process
88666,GO:0140925,"The directed movement of L-phenylalanine from outside of a cell, across the plasma membrane and into the cytosol.",L-phenylalanine import across plasma membrane,biological_process
88667,GO:0140926,Enables the transfer of L-kynurenine from one side of a membrane to the other.,L-kynurenine transmembrane transporter activity,molecular_function
88668,GO:0140927,Enables the transfer of cyclic-di-GMP from one side of a membrane to the other.,cyclic-di-GMP transmembrane transporter activity,molecular_function
88669,GO:0140928,"A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue.",inhibition of non-skeletal tissue mineralization,biological_process
88670,GO:0140929,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-mannose(out) + Na+(out) = D-mannose(in) + Na+(in).,mannose:sodium symporter activity,molecular_function
88671,GO:0140930,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-fructose(out) + Na+(out) = D-fructose(in) + Na+(in).,fructose:sodium symporter activity,molecular_function
88672,GO:0140931,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) + Cl-(out) = neutral L-amino acid(in) + Na+(in)+ Cl-(in).,neutral L-amino acid:sodium:chloride symporter activity,molecular_function
88673,GO:0140932,"Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.",5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity,molecular_function
88674,GO:0140933,Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.,5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity,molecular_function
88675,GO:0140934,A deubiquitinase that cleaves ubiquitin from a histone protein to which it is conjugated.,histone deubiquitinase activity,molecular_function
88676,GO:0140935,"A histone deubiquitinase that cleaves ubiquitin from the conserved C-terminal lysine residue of a histone H2B protein to which it is conjugated. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals.",histone H2B conserved C-terminal lysine deubiquitinase activity,molecular_function
88677,GO:0140936,A histone deubiquitinase that cleaves ubiquitin from a histone H2B protein to which it is conjugated.,histone H2B deubiquitinase activity,molecular_function
88678,GO:0140937,Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 12) + H2O = histone H4 L-lysine (position 12) + acetate. This reaction represents the removal of an acetyl group from lysine at position 12 of the histone H4 protein.,"histone H4K12 deacetylase activity, hydrolytic mechanism",molecular_function
88679,GO:0140938,Catalysis of the reaction: S-adenosyl-L-methionine + a histone H3 = S-adenosyl-L-homocysteine + a methylated histone H3. Histone methylation generally occurs on either an arginine or a lysine residue.,histone H3 methyltransferase activity,molecular_function
88680,GO:0140939,Catalysis of the reaction: Catalysis of the reaction: S-adenosyl-L-methionine + a histone H4 = S-adenosyl-L-homocysteine + a methylated histone H4. Histone methylation generally occurs on either an arginine or a lysine residue.,histone H4 methyltransferase activity,molecular_function
88681,GO:0140940,Catalysis of the reaction: S-adenosyl-L-methionine + a histone H2 = S-adenosyl-L-homocysteine + a methylated histone H2A. Histone methylation generally occurs on either an arginine or a lysine residue.,histone H2A methyltransferase activity,molecular_function
88682,GO:0140941,"Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethylated lysine residue at position 20 of histone H4, producing H4K20me2.",histone H4K20me methyltransferase activity,molecular_function
88683,GO:0140942,"Catalysis of the reaction: L-lysyl9-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl9-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me2.",histone H3K9 dimethyltransferase activity,molecular_function
88684,GO:0140943,"Catalysis of the reaction: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H+ + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to the lysine residue at position 20 of the histone H4 protein, producing histone H4K20me3.",histone H4K20 trimethyltransferase activity,molecular_function
88685,GO:0140944,"Catalysis of the reaction: L-lysyl20-[histone H4] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl20-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 20 of histone H4, producing histone H4K20me.",histone H4K20 monomethyltransferase activity,molecular_function
88686,GO:0140945,"Catalysis of the reaction: L-lysyl4-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl4-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me.",histone H3K4 monomethyltransferase activity,molecular_function
88687,GO:0140946,"Catalysis of the reaction: L-lysyl4-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl4-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me2.",histone H3K4 dimethyltransferase activity,molecular_function
88688,GO:0140947,"Catalysis of the reaction: N6,N6-dimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the dimethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.",histone H3K9me2 methyltransferase activity,molecular_function
88689,GO:0140948,"Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me.",histone H3K9 monomethyltransferase activity,molecular_function
88690,GO:0140949,"Catalysis of the reaction: L-lysyl9-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.",histone H3K9 trimethyltransferase activity,molecular_function
88691,GO:0140950,A histone deubiquitinase that cleaves ubiquitin from a histone H2A protein to which it is conjugated.,histone H2A deubiquitinase activity,molecular_function
88692,GO:0140951,"Catalysis of the reaction: L-lysyl27-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl27-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me3.",histone H3K27 trimethyltransferase activity,molecular_function
88693,GO:0140952,"Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.",histone H3K27 dimethyltransferase activity,molecular_function
88694,GO:0140953,"Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.",histone H3K27 monomethyltransferase activity,molecular_function
88695,GO:0140954,"Catalysis of the reaction: L-lysyl36-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me2.",histone H3K36 dimethyltransferase activity,molecular_function
88696,GO:0140955,"Catalysis of the reaction: L-lysyl36-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl36-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me3.",histone H3K36 trimethyltransferase activity,molecular_function
88697,GO:0140956,"Catalysis of the reaction: L-lysyl79-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl79-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of up to three methyl group to the lysine residue at position 79 of the histone H3 protein, producing H3K79me3.",histone H3K79 trimethyltransferase activity,molecular_function
88698,GO:0140958,"The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases.",target-directed miRNA degradation,biological_process
88699,GO:0140961,Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion.,cellular detoxification of metal ion,biological_process
88700,GO:0140962,"A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.",multicellular organismal-level chemical homeostasis,biological_process
88701,GO:0140964,A homeostatic process involved in the maintenance of a steady state level of auxin within a cell.,intracellular auxin homeostasis,biological_process
88702,GO:0140965,"A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4.",secondary piRNA processing,biological_process
88703,GO:0140966,"The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a Piwi-associated RNA (piRNA).",piRNA-mediated heterochromatin formation,biological_process
88704,GO:0140967,The directed movement of mangnanese ions from outside of a cell into a cell.,manganese import into cell,biological_process
88705,GO:0140968,"Enables the transfer of various organic cations in exchange for a proton, according to the reaction: H+(out) + organic cation(in) = H+(in) + organic cation(out). The transported substrates are usually toxic molecules, drugs and xenobiotics.",polyspecific organic cation:proton antiporter activity,molecular_function
88706,GO:0140969,Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism.,determination of lung left/right asymmetry,biological_process
88707,GO:0140970,"The aggregation, arrangement and bonding together of a set of components to form the AIM2 inflammasome complex.",AIM2 inflammasome complex assembly,biological_process
88708,GO:0140971,"Any process that modulates the frequency, rate or extent of AIM2 inflammasome complex assembly.",regulation of AIM2 inflammasome complex assembly,biological_process
88709,GO:0140972,"Any process that stops, prevents or reduces the frequency, rate or extent of AIM2 inflammasome complex assembly.",negative regulation of AIM2 inflammasome complex assembly,biological_process
88710,GO:0140973,"Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly.",positive regulation of AIM2 inflammasome complex assembly,biological_process
88711,GO:0140974,Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,cellular detoxification of sulfide,biological_process
88712,GO:0140975,"The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. In some cases this can cause malfunctioning of the cells and death of the target organism.",disruption of cellular anatomical structure in another organism,biological_process
88713,GO:0140976,"The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability.",host defense response against symbiont-mediated perturbation of plasma membrane integrity,biological_process
88714,GO:0140977,"Any process carried out at the cellular level that reduces or removes the toxicity of acetone. These may include chemical modification, for example to methylglyoxal.",cellular detoxification of acetone,biological_process
88715,GO:0140978,Binding to a mitochondrial large ribosomal subunit.,mitochondrial large ribosomal subunit binding,molecular_function
88716,GO:0140979,A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell.,intracellular nucleotide homeostasis,biological_process
88717,GO:0140980,A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell.,intracellular nucleoside homeostasis,biological_process
88718,GO:0140981,Catalysis of the reaction: an omega-methyl-medium-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.,medium-chain fatty acid omega-hydroxylase activity,molecular_function
88719,GO:0140982,"Any process that reduce or remove the toxicity of aluminum ions. These can include transport of the aluminum away from sensitive areas, sequesteration, or chemical modification to an inert form.",detoxification of aluminum ion,biological_process
88720,GO:0140983,Catalysis of the reaction: Ca2+(in) + Mn2+(out) = Ca2+(out) + Mn2+(in).,calcium:manganese antiporter activity,molecular_function
88721,GO:0140984,Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.,histone H4K12 methyltransferase activity,molecular_function
88722,GO:0140985,Combining with a chemorepellent and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled chemorepellent receptor activity,molecular_function
88723,GO:0140986,"A G protein-coupled receptor signaling pathway initiated by a chemorepellent binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. cytoskeleton reorganization.",G protein-coupled chemorepellent receptor signaling pathway,biological_process
88724,GO:0140987,Enables the transfer of ATP from one side of a membrane to the other according to the reaction: ATP(out) + phosphate(in) = ATP(in) + phosphate(out).,ATP:phosphate antiporter activity,molecular_function
88725,GO:0140988,Enables the transfer of ADP from one side of a membrane to the other according to the reaction: ADP(out) + phosphate(in) = ADP(in) + phosphate(out).,ADP:phosphate antiporter activity,molecular_function
88726,GO:0140989,Catalysis of the reaction: 7-deoxyloganate + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganate + oxidized [NADPH-hemoprotein reductase].,7-deoxyloganate 7-hydroxylase activity,molecular_function
88727,GO:0140990,"The process involved in converting precursor piRNAs into non-overlapping, contiguous primary piRNAs (approximately 24-30-nt piRNAs with a preference for a 5' uridine (U) via the endonucleolytic activity of cytosolic PIWI. This may include pre-piRNA maturation of 3' ends by trimming and 2'-O-methylation.",primary piRNA processing,biological_process
88728,GO:0140991,"A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping.",piRNA-mediated gene silencing by mRNA destabilization,biological_process
88729,GO:0140993,A catalytic activity that acts on a histone protein. Reversible histone modifications contribute to regulation of gene expression.,histone modifying activity,molecular_function
88730,GO:0140994,A catalytic activity that acts on the RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS). Reversible modifications cof the RNA polymerase II CTD repeats contribute to regulation of RNA polymerase activity.,RNA polymerase II CTD heptapeptide repeat modifying activity,molecular_function
88731,GO:0140995,Catalysis of the transfer of a phosphate group to a histone H2A.,histone H2A kinase activity,molecular_function
88732,GO:0140996,Catalysis of the transfer of a phosphate group to a histone H3.,histone H3 kinase activity,molecular_function
88733,GO:0140997,Catalysis of the transfer of a phosphate group to a histone H4.,histone H4 kinase activity,molecular_function
88734,GO:0140998,Catalysis of the transfer of a phosphate group to a histone H2B.,histone H2B kinase activity,molecular_function
88735,GO:0140999,"Catalysis of the reaction: L-lysyl4-[histone H3] + 3 S-adenosyl-L-methionine = 2 H+ + N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me3.",histone H3K4 trimethyltransferase activity,molecular_function
88736,GO:0141000,Catalysis of the transfer of a ubiquitin molecule to histone 4 at the lysine-91 residue.,histone H4K91 ubiquitin ligase activity,molecular_function
88737,GO:0141002,Catalysis of the reaction: histone H4 L-lysine (position 16) + propionyl-CoA = CoA + H+ + histone H3 N6-propionyl-L-lysyl (position 16).,histone H4K16 propionyltransferase activity,molecular_function
88738,GO:0141003,Catalysis of the transfer of a phosphate group to a histone variant H2AX.,histone H2AX kinase activity,molecular_function
88739,GO:0141005,A transposable element silencing mechanism involving heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.,transposable element silencing by heterochromatin formation,biological_process
88740,GO:0141006,A transposable element silencing mechanism in which a Piwi-associated RNA (piRNA) triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.,transposable element silencing by piRNA-mediated heterochromatin formation,biological_process
88741,GO:0141007,A transposable element silencing mechanism in which a siRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.,transposable element silencing by siRNA-mediated heterochromatin formation,biological_process
88742,GO:0141008,A transposable element silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation.,transposable element silencing by mRNA destabilization,biological_process
88743,GO:0141009,A transposable element silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a Piwi-associated RNA (piRNA).,transposable element silencing by piRNA-mediated mRNA destabilization,biological_process
88744,GO:0141010,"A transposable element silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.",transposable element silencing by siRNA-mediated DNA methylation,biological_process
88745,GO:0141011,A transposable element silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA.,transposable element silencing by siRNA-mediated mRNA destabilization,biological_process
88746,GO:0141013,"The directed import of purine nucleotide from the cytosol, across the lysosomal membrane, into the lysosome.",purine nucleotide import into lysosome,biological_process
88747,GO:0141014,"A cellular process that results in the silencing of ribosomes in quiescent cells. Quiescence takes place when cells encounter unfavorable conditions and cease to grow in bacteria and yeast. It also takes place in some specialized cells in higher eukaryotes, such as eggs. Ribosomes in a hibernation state are kept silent via association with proteins with inhibitory and protective functions.",cytosolic ribosome hibernation,biological_process
88748,GO:0141016,"Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site.",G/T mismatch-specific thymine-DNA glycosylase activity,molecular_function
88749,GO:0141017,"A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation.",effector-mediated induction of cell cycle reactivation in host,biological_process
88750,GO:0141018,The attachment of a symbiont to its host by binding to a component of the host extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont to host via host extracellular matrix,biological_process
88751,GO:0141023,A process in which a symbiont alters or subverts host cell adhesion ito its extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host cell-cell adhesion,biological_process
88752,GO:0141024,The attachment of a symbiont to its host by binding to a carbohydrate on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont to host cell surface via host membrane carbohydrate,biological_process
88753,GO:0141025,The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont to host cell surface via host glycoprotein,biological_process
88754,GO:0141026,The attachment of a symbiont to its host by binding to cholesterol on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.,adhesion of symbiont to host cell surface via host membrane cholesterol,biological_process
88755,GO:0141027,The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host actin cytoskeleton,biological_process
88756,GO:0141028,The process in which an organism effects a change that impairs the structure or function of the host microtubule cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host microtubule cytoskeleton,biological_process
88757,GO:0141029,A process in which a symbiont alters or subverts focal adhesion in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host focal adhesion,biological_process
88758,GO:0141030,The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host actin cytoskeleton via filamentous actin depolymerization,biological_process
88759,GO:0141031,The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by actin crosslinking the host actin filaments. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host actin cytoskeleton via actin crosslinking,biological_process
88760,GO:0141032,"The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization,biological_process
88761,GO:0141033,The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by polymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host actin cytoskeleton via actin polymerization,biological_process
88762,GO:0141034,The process in which an organism effects a change that disrupts the host actin cytoskeleton by inhibiting host actin from polymerizing. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host actin cytoskeleton via inhibition of actin polymerization,biological_process
88763,GO:0141035,"Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + CTP = a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H+.",CTP-dependent diacylglycerol kinase activity,molecular_function
88764,GO:0141038,Binds to and increases the activity of a phosphatidylinositol 3-kinase (PI3K).,phosphatidylinositol 3-kinase activator activity,molecular_function
88765,GO:0141039,Binds to and decreases the activity of a phosphatidylinositol 3-kinase (PI3K).,phosphatidylinositol 3-kinase inhibitor activity,molecular_function
88766,GO:0141040,Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH. This reaction is the second (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.,very-long-chain 3-oxoacyl-CoA reductase activity,molecular_function
88767,GO:0141042,"The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated cAMP intoxication of host cell,biological_process
88768,GO:0141043,"A process by which a symbiont avoids recognition by host's innate immune response by altering, concealing or destroying a conserved symbiont molecule recognized by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated evasion of host innate immune response,biological_process
88769,GO:0141044,"The global programming of epigenetic modifications following binucleate central cell fertilization. This involves DNA methylation at the silent allele. In the endosperm, maternal genomes are hypomethylated compared with the paternal genome.",epigenetic programming in the endosperm,biological_process
88770,GO:0141046,"Isoenergetic transfer of an Atg8 family modifier from one protein to a phosphatidylethanolamine or phosphatidylserine on a membrane, via the reaction X-Atg8 + Y = Y-Atg8 + X.",Atg8-family conjugating enzyme activity,molecular_function
88771,GO:0141047,"A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another molecule (for example a protein or a lipid) where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.",molecular tag activity,molecular_function
88772,GO:0141048,"A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to a lipid, where it acts as a marker for a membrane, recognized by the cellular apparatus to target the tagged protein for some cellular process such as autophagy.",membrane tag activity,molecular_function
88773,GO:0141049,Catalysis of the reaction: glutathionylated protein (PSSG) + glutathione (GSH) = protein-thiol (PSH) + glutathione disulfide (GSSG). The reaction may proceed via a 'monothiol' or 'dithiol' mechanism.,protein-glutathione oxidoreductase (glutathione) activity,molecular_function
88774,GO:0141050,Removal of an acetyl group from a lysine residue in a histone H3.,histone H3K deacetylase activity,molecular_function
88775,GO:0141051,Removal of an acetyl group from a lysine residue in a histone H4.,histone H4K deacetylase activity,molecular_function
88776,GO:0141052,Catalysis of the removal of a methyl group from a modified lysine residue of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H3 demethylase activity,molecular_function
88777,GO:0141053,Catalysis of the transfer of ubiquitin to a histone H2A substrate.,histone H2A ubiquitin ligase activity,molecular_function
88778,GO:0141054,Catalysis of the transfer of ubiquitin to a histone H2B substrate.,histone H2B ubiquitin ligase activity,molecular_function
88779,GO:0141055,Catalysis of the transfer of ubiquitin to a histone H3 substrate.,histone H3 ubiquitin ligase activity,molecular_function
88780,GO:0141056,Catalysis of the transfer of ubiquitin to a histone H4 substrate.,histone H4 ubiquitin ligase activity,molecular_function
88781,GO:0141057,"Catalysis of the reaction: H2O + histone H3 L-arginyl = histone H3 L-citrullyl + NH4+, resulting in histone H3 citrullination.",histone H3 arginine deiminase activity,molecular_function
88782,GO:0141058,Catalysis of the removal of a methyl group from a modified lysine residue of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H4 demethylase activity,molecular_function
88783,GO:0141059,"Any process in which a symbiont interferes with a host antimicrobial peptide, for example by cleavage or degradation.",symbiont-mediated disruption of host antimicrobial peptide activity,biological_process
88784,GO:0141060,"The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure.",disruption of anatomical structure in another organism,biological_process
88785,GO:0141061,"The disruption of a cell of another organism, leading to damage or temporary subversion of that cell.",disruption of cell in another organism,biological_process
88786,GO:0141063,"The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation.",epigenetic programming in the central cell,biological_process
88787,GO:0141064,"A process that contributes to the onset of de novo transcription from the zygotic genome as part of the maternal-to-zygote transition in gene expression. The zygote overcomes the silencing that has been established. The cause of this silencing could be due to several factors: chromatin modifications leading to repression, or lack of adequate transcription machinery.",zygotic genome activation,biological_process
88788,GO:0141065,The chemical reactions and pathways resulting in the clearance of maternal mRNA transcripts from the zygote as part of the maternal-to-zygote transition in gene expression.,maternal mRNA clearance,biological_process
88789,GO:0141066,The process in which an organism effects a change that impairs the structure or function of the host extracellular matrix.,symbiont-mediated disruption of host extracellular matrix,biological_process
88790,GO:0141067,A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell.,intracellular nitrogen homeostasis,biological_process
88791,GO:0141068,"The establishment of epigenetic modifications (imprints) in autosomal (non-sexual) chromosomes during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.",autosome genomic imprinting,biological_process
88792,GO:0141069,Binds to and decreases the activity of the ligand of a signaling receptor.,receptor ligand inhibitor activity,molecular_function
88793,GO:0141070,"A process in which a symbiont interferes with, inhibits or disrupts a MAPK signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host MAPK cascade,biological_process
88794,GO:0141071,"A process in which a symbiont subverts a MAPK signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host MAPK cascade,biological_process
88795,GO:0141072,"A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway,biological_process
88796,GO:0141073,A process in which a symbiont alters or subverts opsonization by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host opsonization,biological_process
88797,GO:0141074,"A process in which a virus interferes with, inhibits or disrupt a cGAS/STING signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host cGAS-STING signal transduction,biological_process
88798,GO:0141079,"A process in which a symbiont subverts an inflammasome-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host inflammasome-mediated signal transduction,biological_process
88799,GO:0141080,"A process in which a symbiont subverts an interferon-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation.",symbiont-mediated activation of host interferon signaling pathway,biological_process
88800,GO:0141081,"A process in which a symbiont interferes with, inhibits or stops an inflammasome-mediated signal transduction pathway in the host organism by interfering with its normal execution. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host inflammasome-mediated signal transduction,biological_process
88801,GO:0141082,"A process in which a symbiont interferes with, inhibits or disrupts the host reactive oxygen species (ROS)-mediated innate immune response by directly degrading host ROS. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated detoxification of host-generated reactive oxygen species,biological_process
88802,GO:0141083,"A process in which a symbiont interferes with, inhibits or disrupts the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host reactive oxygen species generation,biological_process
88803,GO:0141084,"An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis.",inflammasome-mediated signaling pathway,biological_process
88804,GO:0141085,"Any process that modulates the frequency, rate or extent of an inflammasome-mediated signaling pathway.",regulation of inflammasome-mediated signaling pathway,biological_process
88805,GO:0141086,"Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway.",negative regulation of inflammasome-mediated signaling pathway,biological_process
88806,GO:0141087,"Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.",positive regulation of inflammasome-mediated signaling pathway,biological_process
88807,GO:0141089,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of glucose.",glucose sensor activity,molecular_function
88808,GO:0141090,Catalysis of the reaction: protein phospho-serine + inositol 5-triphosphate pentakisphosphate = protein diphospho-serine + inositol 5-diphosphate pentakisphosphate.,protein serine pyrophosphorylase activity,molecular_function
88809,GO:0141091,"The series of molecular signals initiated by an extracellular ligand binding to a member of the transforming growth factor receptor superfamily, and ending with the regulation of a downstream cellular process, e.g. transcription.",transforming growth factor beta receptor superfamily signaling pathway,biological_process
88810,GO:0141092,"Any process that increases the rate, frequency or extent of nodal signaling pathway.",positive regulation of nodal signaling pathway,biological_process
88811,GO:0141093,"Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 2-iminoacetate + 5'-deoxyadenosine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + H+ + L-methionine.",5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity,molecular_function
88812,GO:0141094,"Binding to a DNA loop anchor, a region of chromosome that defines the ends of a DNA loop where two parts of same DNA strand are held in close physical proximity. For example, in animals, the anchors of DNA loops are convergently oriented CTCF binding sites during interphase.",DNA loop anchor binding,molecular_function
88813,GO:0141096,A DNA-binding transcription repressor activity regulated by binding to a ligand and that inhibits the transcription of specific genes and gene sets.,ligand-modulated transcription repressor activity,molecular_function
88814,GO:0141097,A DNA-binding transcription activator activity regulated by binding to a ligand and that activates the transcription of specific genes and gene sets.,ligand-modulated transcription activator activity,molecular_function
88815,GO:0141098,Catalysis of the reaction: cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H+ + S-adenosyl-L-homocysteine.,tRNA (cytidine(34)-2'-O-ribose)-methyltransferase activity,molecular_function
88816,GO:0141100,Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 18 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 18 in tRNA + H+.,tRNA (guanine(18)-2'-O-ribose)-methyltransferase activity,molecular_function
88817,GO:0141101,Catalysis of the reaction: Catalysis of the reaction: S-adenosyl-L-methionine + uridine44 in tRNASer = 2'-O-methyluridine44 in tRNASer + H+ + S-adenosyl-L-homocysteine.,tRNA(Ser) (uridine(44)-2'-O-ribose)-methyltransferase activity,molecular_function
88818,GO:0141102,Catalysis of the reaction: 5-carboxymethylaminomethyluridine34 in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine34 in tRNA(Leu) + H+ + S-adenosyl-L-homocysteine.,tRNA (5-carboxymethylaminomethyluridine(34)-2'-O-ribose)-methyltransferase activity,molecular_function
88819,GO:0141104,"A process in which a symbiont initiates, promotes, or enhances a G protein-coupled receptor signal transduction pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host G protein-coupled receptor signal transduction,biological_process
88820,GO:0141106,Binds to and increases the activity of a methyltransferase.,tRNA methyltransferase activator activity,molecular_function
88821,GO:0141107,Binds to and modulates the activity of a methyltransferase.,methyltransferase regulator activity,molecular_function
88822,GO:0141108,Binds to and modulates the activity of a transporter.,transporter regulator activity,molecular_function
88823,GO:0141109,Binds to and increases the activity of a transporter.,transporter activator activity,molecular_function
88824,GO:0141110,"Binds to and stops, prevents, or reduces the activity of a transporter.",transporter inhibitor activity,molecular_function
88825,GO:0141111,"Any process that activates or increases the frequency, rate or extent of of cGAS/STING signaling pathway.",positive regulation of cGAS/STING signaling pathway,biological_process
88826,GO:0141112,"The process of bringing together chromosomes fragments resulting from DNA damage. Broken chromosome tethering during mitosis ensures clustered segregation of the fragments to a single daughter cell nucleus, facilitating re-ligation with limited chromosome scattering and loss and enhancing genome integrity.",broken chromosome clustering,biological_process
88827,GO:0141113,"Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway, planar cell polarity pathway.","negative regulation of Wnt signaling pathway, planar cell polarity pathway",biological_process
88828,GO:0141115,A process by which a symbiont disrupts or prematurely activates host complement so that its microbial-destroying activities fail.,symbiont-mediated suppression of host complement activation by inactivation of complement proteins,biological_process
88829,GO:0141116,A process by which a symbiont prevents host complement activation by sequestering it away from its surface.,symbiont-mediated suppression of host complement activation by complement sequestering,biological_process
88830,GO:0141117,"A process by which a symbiont prevents the activation of host complement by binding a soluble complement control protein (CCP) of the host and recruiting it to the microbe surface. The normal role of CCPs is to prevent complement activation on 'self' cellular targets. When soluble CCPs are recuited to the surface of a microbe, the complement fails to activate.",symbiont-mediated suppression of host complement activation by recruitment of complement control protein,biological_process
88831,GO:0141118,Catalysis of the reaction: Fe(II)-heme b-[protein] + nitric oxide + O2 = Fe(III)-heme b-[protein] + nitrate.,"nitric oxide dioxygenase activity, heme protein as donor",molecular_function
88832,GO:0141119,"The process that maintains methylated cytosine in newly synthesized DNA following DNA replication. After the establishment of novel DNA methylation marks, the newly created patterns must be faithfully transmitted by maintenance DNA methyltransferases during cell division.",chromosomal DNA methylation maintenance following DNA replication,biological_process
88833,GO:0141122,Catalysis of the breakage of a nitrogen-oxygen bond by means other than hydrolysis and oxidation.,nitrogen-oxygen lyase activity,molecular_function
88834,GO:0141123,"The disruption of the skin of another organism, leading to damage or temporary subversion of the skin.",venom-mediated dermonecrosis in another organism,biological_process
88835,GO:0141124,An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways.,intracellular signaling cassette,biological_process
88836,GO:0141125,Catalysis of the reaction: queuosine34 in tRNA + UDP-alpha-D-galactose = H+ + O-5''-beta-D-galactosylqueuosine34 in tRNATyr + UDP. Substrates include tRNA(Tyr) and tRNA(Asp).,tRNA-queuosine(34) galactosyltransferase activity,molecular_function
88837,GO:0141126,Catalysis of the reaction: a short-chain fatty acyl-CoA + H2O = a short fatty acid + CoA + H+. A short-chain fatty acid has an aliphatic tail of less than 6 carbons.,short-chain fatty acyl-CoA hydrolase activity,molecular_function
88838,GO:0141127,A process in which a symbiont alters a Rab protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host Rab small GTPase signal transduction,biological_process
88839,GO:0141128,"A process by which a symbiont superantigen elicits a strong immune response by activating a large number of T cells in a non-specific manner. Unlike conventional antigens, which activate T cells by interacting with specific receptors on the surface of these cells, superantigens can stimulate T cells by binding to regions outside the antigen-binding site. Superantigens can activate a large proportion of T cells, leading to an exaggerated immune response. This excessive activation can result in...",symbiont-mediated non-specific activation of host T-cells,biological_process
88840,GO:0141129,A process by which a symbiont alters or subverts a host cell surface receptor-mediated signal transduction pathway by binding to and inhibiting the receptor of the pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host signal transduction pathway via antagonism of host cell surface receptor,biological_process
88841,GO:0141130,A process in which a symbiont inhibits or disrupts translation of mRNA into protein in its host by inactivating its ribosomes.,symbiont-mediated inactivation of host ribosome,biological_process
88842,GO:0141131,Catalysis of the reaction: 2-oxoglutarate + an N6-methyl-2'-deoxyadenosine in DNA + O2 = a 2'-deoxyadenosine in DNA + CO2 + formaldehyde + succinate.,DNA N6-methyladenine demethylase activity,molecular_function
88843,GO:0141133,Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 3 H+ + 4 S-adenosyl-L-homocysteine.,diphthine methyl ester synthase activity,molecular_function
88844,GO:0141134,A process in which a symbiont subverts a signal transduction pathway in the host organism by binding to and enhancing the activation of the receptor of the pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated activation of host signal transduction pathway via agonism of host cell surface receptor,biological_process
88845,GO:0141135,"A process in which a symbiont interferes with, inhibits or disrupts a chemokine signaling pathway, a G protein-coupled receptor signal transduction pathway activated by a chemokine. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host chemokine signal transduction pathway,biological_process
88846,GO:0141137,"An epigenetic process that increases gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA demethylation.","positive regulation of gene expression, epigenetic",biological_process
88847,GO:0141139,"The disruption of the host mucosa by a symbiont, leading to damage or temporary subversion of that tissue. The mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs.",symbiont-mediated disruption of host mucosa,biological_process
88848,GO:0141140,"A process in which a symbiont interferes with, inhibits or disrupts the normal execution of the immunoglobulin-mediated immune response of the host organism. One common mechanism by which this happens is the direct inhibition of immunoglobulin activity, by direct binding or modification. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host immunoglobulin-mediated immune response,biological_process
88849,GO:0141141,"A process by which a symbiont avoids recognition by host's innate immune response by altering or concealing a conserved molecule recognized by the host's cell surface and intracellular pattern recognition receptors, including Toll-like and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated evasion of recognition by host pattern recognition receptor,biological_process
88850,GO:0141142,A process in which a symbiont moves across a tissue barrier of the host to transports itself across an extracellular cellular matrix barrier or between the cells of a tissue. This involves the temporary or permanent breaching of the tissue barrier.,symbiont-mediated migration across host tissue barrier,biological_process
88851,GO:0141144,A process in which a symbiont damages or impairs host neutrophil extracellular traps. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated disruption of host neutrophil extracellular traps,biological_process
88852,GO:0141145,A process in which a symbiont inhibits or disrupts the formation of neutrophil extracellular traps by the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host neutrophil extracellular trap formation,biological_process
88853,GO:0141146,"The process in which an organism effects a change that impairs the structure or function of a host tissue. This can occur via the disruption of the extracellular matrix, or the detachment of cells from the extracellular matrix, or the dissociation of the cells composing that tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated disruption of host tissue,biological_process
88854,GO:0141147,Enables the transmembrane transfer of a solute by a channel that opens when calcium ions bind on the intracellular side of the channel complex or one of its constituent parts.,intracellularly calcium-gated channel activity,molecular_function
88855,GO:0141148,"Catalysis of the reaction: a 2,3-saturated acyl-[ACP] + NADP+ = a (2E)-enoyl-[ACP] + H+ + NADPH.",enoyl-[acyl-carrier-protein] reductase (NADPH) activity,molecular_function
88856,GO:0141149,"Any process that modulates the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.",regulation of nitric oxide-cGMP mediated signal transduction,biological_process
88857,GO:0141150,"Any process that increases the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.",positive regulation of nitric oxide-cGMP mediated signal transduction,biological_process
88858,GO:0141151,"Any process that decreases the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.",negative regulation of nitric oxide-cGMP mediated signal transduction,biological_process
88859,GO:0141152,Catalysis of the reaction: NAD+ + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H+ + NADH.,glycerol-3-phosphate dehydrogenase (NAD+) activity,molecular_function
88860,GO:0141153,NADP+ + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H+ + NADPH.,glycerol-3-phosphate dehydrogenase (NADP+) activity,molecular_function
88861,GO:0141154,"A process in which a symbiont inhibits or disrupts the host shutoff of host translation, a host response that prevents mRNA in the cell to be translated, to prevent the symbiont from expressing its genes. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host-directed shutoff of host translation,biological_process
88862,GO:0141155,"A process in which a symbiont inhibits or disrupts the translation elongation of host mRNA into protein, for example by directly inhibiting elongation factors. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host translation elongation,biological_process
88863,GO:0141156,"An intracellular signaling cassette that starts with production of cyclic AMP (cAMP) by adenylate cyclase (either transmembrane or soluble), which activates protein kinase A, and ends with activation of downstream effectors such as the transcription factor CREB that further transmit the signal within the cell.",cAMP/PKA signal transduction,biological_process
88864,GO:0141157,A process in which a symbiont inhibits or disrupts the normal execution of  host exocytosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host exocytosis,biological_process
88865,GO:0141158,A process in which a symbiont inhibits or disrupts the normal maturation of host phagosomes. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host phagosome maturation,biological_process
88866,GO:0141159,"A process in which a symbiont inhibits or disrupts the normal acidification of host phagosomes. Mechanisms by which a symbiont prevents host phagosome acidification include the inhibitition of host V-ATPase, the proton pump that acidifies the phagosome, or disruption of the phagosome membrane by pore-forming toxin. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host phagosome acidification,biological_process
88867,GO:0141160,The process in which an organism effects a change that impairs the structure or function of host phagosomes.,symbiont-mediated disruption of host phagosome,biological_process
88868,GO:0141161,"Any process that modulates the frequency, rate or extent of cAMP/PKA signal transduction.",regulation of cAMP/PKA signal transduction,biological_process
88869,GO:0141162,"Any process that stops, prevents or reduces the frequency, rate or extent of cAMP/PKA signal transduction.",negative regulation of cAMP/PKA signal transduction,biological_process
88870,GO:0141163,"Any process that activates or increases the frequency, rate or extent of cAMP/PKA signal transduction.",positive regulation of cAMP/PKA signal transduction,biological_process
88871,GO:0141164,"The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the mitochondrion, which are targeted for degradation.",mitochondrial protein quality control,biological_process
88872,GO:0141165,Enables the transfer of a glucosinolate across a membrane.,glucosinolate transmembrane transporter activity,molecular_function
88873,GO:0141166,"A process that chemically modifies 5-methylcytosine (5meC) to make it a substrate for the base excision repair pathway, which then restores the unmodified cytosine.",chromosomal 5-methylcytosine DNA demethylation pathway,biological_process
88874,GO:0141167,"An epigenetic cytosine DNA demethylation pathway that starts with the enzymatic oxidation of the 5-methylcytosine (5meC) to generate 5-hydroxymethylcytosine (5hmC), which successively converted to 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC).  A DNA glycosylase (e. g. TDG) recognizes the  intermediate bases 5fC and 5caC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.","chromosomal 5-methylcytosine DNA demethylation, oxidation pathway",biological_process
88875,GO:0141168,"An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. A DNA glycosylase (e. g. TDG) recognizes the T mispaired with a G or the 5hmC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.","chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway",biological_process
88876,GO:0141169,"An epigenetic cytosine DNA demethylation pathway that involves a DNA glycosylase that directly excises 5-methylcytosine (5-meC) to initiate its replacement with unmethylated cytosine through base excision repair. This pathway is known to occur in plants. In addition to CG sites, plants also methylate cytosines within CHH and CNG sequences.","chromosomal 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway",biological_process
88877,GO:0141170,"Any process that activates or increases the frequency, rate or extent of positive regulation of 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway.","positive regulation of 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway",biological_process
88878,GO:0141171,The process in which a symbiont effects a change that impairs the structure or function of a host membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host membrane,biological_process
88879,GO:0141173,"A process by which a symbiont inhibits or disrupts pro-inflammatory cytokine signaling in the host organism, either by disruption of production, sequesteration, or destruction of at least one component of the signaling pathway. Pro-inflammatory cytokines include: IL-1, IL-12, IL-18, TNF, IFN-gamma, and GM-CSF. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host pro-inflammatory cytokine signaling,biological_process
88880,GO:0141174,"A process by which a symbiont inhibits or disrupts anti-inflammatory cytokine signaling in the host organism, either by disruption of production, sequesteration, or destruction of at least one component of the signaling pathway.  Anti-inflammatory cytokines include: interleukin (IL)-1, IL-4, IL-6, IL-10, IL-11, and IL-13. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated suppression of host anti-inflammatory cytokine signaling,biological_process
88881,GO:0141175,"A protein-protein adaptor that acts as a platform for receptor clustering, often serving to amplify the sensitivity of a signaling response.",receptor clustering activity,molecular_function
88882,GO:0141176,"A small RNA-based gene silencing process in which Piwi-associated RNAs (piRNAs) guide de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.",gene silencing by piRNA-directed DNA methylation,biological_process
88883,GO:0141177,"A process by which a symbiont mitigates the effects of recognition by a host innate immune effector. Effectors have a direct activity against a symbiont and include complement, antimicrobial peptides, and bacterial restriction enzymes. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated evasion of recognition by host innate immune effector,biological_process
88884,GO:0141178,A process by which a symbiont avoids the effects of recognition by host  complement by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated evasion of recognition by host complement,biological_process
88885,GO:0141179,A process by which a symbiont avoids the effects of recognition by a host  antimicrobial peptide by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated evasion of recognition by host antimicrobial peptide,biological_process
88886,GO:0141180,A chromatin-protein adaptor activity that bridges dsDNA and chromatin proteins to bring regions of a chromosome in proximity. The DNA:DNA:RNA triple-helical structure is formed non-Watson-Crick base-pairing.,dsDNA-RNA triple helix-forming chromatin adaptor activity,molecular_function
88887,GO:0141184,"A process in which a symbiont subverts an anti-inflammatory cytokine signaling pathway in the host organism by initiating, promoting, or enhancing its activation.",symbiont-mediated activation of host anti-inflammatory cytokine signaling,biological_process
88888,GO:0141185,A molecular adaptor recognizes and binds a target protein containing a UFM1 modification and brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.,UFM1-modified protein reader activity,molecular_function
88889,GO:0141187,The biosynthetic process resulting in the formation of a nucleic acid.,nucleic acid biosynthetic process,biological_process
88890,GO:0141188,The cellular DNA metabolic process resulting in the breakdown of a nucleic acid.,nucleic acid catabolic process,biological_process
88891,GO:0141190,"A G protein-coupled receptor signaling pathway that starts with an opsin molecule being activated by a photon. Opsins include rhodopsin and others visual receptors bind heterotrimeric transducin G proteins upon activation. Activated transducin alpha-subunit activates cGMP phosphodiesterase, which breaks down cGMP. The decrease in cGMP concentration leads to closure of cGMP-gated (CNG) channels, blockage of Na+ influx, and hyperpolarization of photoreceptor plasma membrane, leading to transmis...",transducin-mediated opsin signaling pathway,biological_process
88892,GO:0141191,"Any process that stops, prevents, or reduces the frequency, rate or extent of HRI-mediated signaling.",negative regulation of HRI-mediated signaling,biological_process
88893,GO:0141192,"Catalysis of the reaction: 2 ATP + H+ = diphosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.",ATP:ATP adenylyltransferase activity,molecular_function
88894,GO:0141193,"The series of molecular signals initiated by a signaling molecule binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",nuclear receptor-mediated signaling pathway,biological_process
88895,GO:0141194,The formation of heterochromatin into a heterochromatin domain by a process mediated by a small interfering siRNA.,siRNA-mediated heterochromatin formation,biological_process
88896,GO:0141196,"A transposable element silencing mechanism mediated by Piwi-associated RNA (piRNA)-directed DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.",transposable element silencing by piRNA-mediated DNA methylation,biological_process
88897,GO:0141197,"Catalysis of the reaction: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H+ + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin].",4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin),molecular_function
88898,GO:0141198,"A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at various positions of the ubiquitin monomers, forming branched linkages, such as K11/K48- or K11/K63-linked chains.",protein branched polyubiquitination,biological_process
88899,GO:0141200,Catalysis of the reaction: UTP + thiamine = UMP + thiamine diphosphate.,UTP thiamine diphosphokinase activity,molecular_function
88900,GO:0141201,A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins.,pyroptotic cell death,biological_process
88901,GO:0141203,"A process by which a symbiont prevents host complement activation by recruiting host proteases, destroying the complement before it has its effect on the symbiont.",symbiont-mediated suppression of host complement activation by activation of host proteases,biological_process
88902,GO:0141204,The directed movement of dipeptide from the lysosomal lumen across the lysosomal membrane and into the cytosol.,dipeptide transmembrane transport from lysosomal lumen to cytosol,biological_process
88903,GO:0141207,Catalysis of the reaction: lactate + ATP + L-lysyl-[protein] = N(6)-lactoyl-L-lysyl-[protein]+ AMP + diphosphate. Can also act on free lactate.,peptide lactyltransferase (ATP-dependent) activity,molecular_function
88904,GO:0141208,"Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] + NAD = L-lysyl-[protein] + nicotinamide +2''-O-lactoyl-ADP-D-ribose, transfering a lactoyl group attached to a lysine residue in a protein to NAD.",NAD-dependent protein lysine delactylase activity,molecular_function
88905,GO:0141209,"A nuclear receptor-mediated signaling pathway initiated by an oxysterol binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.",oxysterol receptor signaling pathway,biological_process
88906,GO:0141212,"An intracellular signaling cassette that starts with activation of phospholipase C (PLC) activity and ends with the activation of protein kinase C (PKC). PLC produces inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). IP3 regulates the opening of calcium channels in intracellular calcium store, leading to the release of calcium into the cytosol. Calcium and DAG activate protein kinase C (PKC), which in turn activates downstream effectors. This cassette is often part of the phospholi...",phospholipase C/protein kinase C signal transduction,biological_process
88907,GO:0141213,A process in which a symbiont alters or subverts vacuole organization in its host organism to form a protected environment in which it can replicate. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated generation of symbiont replication vacuole,biological_process
88908,GO:0141214,"Any process that activates or increases the frequency, rate or extent of phospholipase C/protein kinase C signal transduction.",positive regulation of phospholipase C/protein kinase C signal transduction,biological_process
88909,GO:0141215,Catalysis of the reaction: N-acetyltaurine + H2O = acetate + taurine.,N-acetyltaurine hydrolase activity,molecular_function
88910,GO:0141217,The posttranscriptional addition of a carbohydrate or carbohydrate derivative unit to residues in an RNA molecule. GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell surface.,glycoRNA biosynthetic process,biological_process
88911,GO:0141218,Catalysis of the reaction: N6-acyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-acyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].,NAD-dependent protein lysine deacylase activity,molecular_function
88912,GO:0141221,Catalysis of the reaction: H2O + N6-acetyl-L-lysyl-[histone] = acetate + L-lysyl-[histone].,"histone deacetylase activity, hydrolytic mechanism",molecular_function
88913,GO:0141222,"Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + NAD+ + H2O = histone H3 L-lysine (position 14) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K4 to NAD, producing nicotinamide.","histone H3K4 deacetylase activity, NAD-dependent",molecular_function
88914,GO:0141223,Catalysis of the reaction: hydrogen sulfide + O-succinyl-L-serine = L-cysteine + succinate.,"cysteine synthase activity, acting on O-succinyl-L-serine",molecular_function
88915,GO:0150001,A dendrite emerging from the cell body (the soma) of a neuron.,primary dendrite,cellular_component
88916,GO:0150002,The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).,distal dendrite,cellular_component
88917,GO:0150003,"Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.",regulation of spontaneous synaptic transmission,biological_process
88918,GO:0150004,The part of the dendritic spine neck where the spine arises from the dendritic shaft.,dendritic spine origin,cellular_component
88919,GO:0150005,A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.,enzyme activator complex,cellular_component
88920,GO:0150006,A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.,urease activator complex,cellular_component
88921,GO:0150007,Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.,clathrin-dependent synaptic vesicle endocytosis,biological_process
88922,GO:0150008,Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.,bulk synaptic vesicle endocytosis,biological_process
88923,GO:0150011,"Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.",regulation of neuron projection arborization,biological_process
88924,GO:0150012,"Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.",positive regulation of neuron projection arborization,biological_process
88925,GO:0150013,"Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.",negative regulation of neuron projection arborization,biological_process
88926,GO:0150014,"Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).",apical distal dendrite,cellular_component
88927,GO:0150015,"The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma).",apical proximal dendrite,cellular_component
88928,GO:0150016,"Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).",basal distal dendrite,cellular_component
88929,GO:0150017,"Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).",basal proximal dendrite,cellular_component
88930,GO:0150018,"The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.",basal dendrite development,biological_process
88931,GO:0150019,The process in which the anatomical structures of a basal dendrite are generated and organized.,basal dendrite morphogenesis,biological_process
88932,GO:0150020,The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.,basal dendrite arborization,biological_process
88933,GO:0150021,The process in which the anatomical structures of an apical dendrite are generated and organized.,apical dendrite morphogenesis,biological_process
88934,GO:0150022,"The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.",apical dendrite development,biological_process
88935,GO:0150023,The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.,apical dendrite arborization,biological_process
88936,GO:0150024,The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.,oxidised low-density lipoprotein particle clearance,biological_process
88937,GO:0150025,Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.,oxidised low-density lipoprotein particle receptor activity,molecular_function
88938,GO:0150031,"Any process that modulates the frequency, rate or extent of protein localization to lysosome.",regulation of protein localization to lysosome,biological_process
88939,GO:0150032,"Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.",positive regulation of protein localization to lysosome,biological_process
88940,GO:0150033,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.",negative regulation of protein localization to lysosome,biological_process
88941,GO:0150034,That part of an axon close to and including the growth cone or the axon terminus.,distal axon,cellular_component
88942,GO:0150035,"Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.","regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission",biological_process
88943,GO:0150036,"Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.","regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission",biological_process
88944,GO:0150037,"Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.",regulation of calcium-dependent activation of synaptic vesicle fusion,biological_process
88945,GO:0150038,"The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.",postsynaptic dense core vesicle exocytosis,biological_process
88946,GO:0150043,The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.,structural constituent of synapse-associated extracellular matrix,molecular_function
88947,GO:0150044,"Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.",regulation of postsynaptic dense core vesicle exocytosis,biological_process
88948,GO:0150045,"Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.",regulation of synaptic signaling by nitric oxide,biological_process
88949,GO:0150048,A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.,cerebellar granule cell to Purkinje cell synapse,cellular_component
88950,GO:0150050,The portion of the septin cytoskeleton contained within the postsynapse.,postsynaptic septin cytoskeleton,cellular_component
88951,GO:0150051,The network of the Golgi apparatus structures located within the postsynapse.,postsynaptic Golgi apparatus,cellular_component
88952,GO:0150052,"Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.",regulation of postsynapse assembly,biological_process
88953,GO:0150053,A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.,cerebellar climbing fiber to Purkinje cell synapse,cellular_component
88954,GO:0150054,"Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.",regulation of postsynaptic neurotransmitter receptor diffusion trapping,biological_process
88955,GO:0150056,A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).,amylin receptor complex 1,cellular_component
88956,GO:0150057,A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).,amylin receptor complex 2,cellular_component
88957,GO:0150058,A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways.,amylin receptor complex 3,cellular_component
88958,GO:0150059,"The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).",amylin receptor 1 signaling pathway,biological_process
88959,GO:0150060,"The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).",amylin receptor 2 signaling pathway,biological_process
88960,GO:0150061,"The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.",amylin receptor 3 signaling pathway,biological_process
88961,GO:0150062,Synaptic pruning mediated by complement system signaling.,complement-mediated synapse pruning,biological_process
88962,GO:0150063,"The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.",visual system development,biological_process
88963,GO:0150064,"Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus.",vertebrate eye-specific patterning,biological_process
88964,GO:0150065,"Any process that modulates the frequency, rate or extent of deacetylase activity.",regulation of deacetylase activity,biological_process
88965,GO:0150074,"Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.",positive regulation of protein-glutamine gamma-glutamyltransferase activity,biological_process
88966,GO:0150076,The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.,neuroinflammatory response,biological_process
88967,GO:0150077,"Any process that modulates the frequency, rate or extent of neuroinflammatory response.",regulation of neuroinflammatory response,biological_process
88968,GO:0150078,"Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.",positive regulation of neuroinflammatory response,biological_process
88969,GO:0150079,"Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.",negative regulation of neuroinflammatory response,biological_process
88970,GO:0150086,A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.,multiple synapse bouton,cellular_component
88971,GO:0150087,A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.,"multiple synapse bouton, contacting single dendrite",cellular_component
88972,GO:0150088,A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.,"multiple synapse bouton, contacting multiple dendrites",cellular_component
88973,GO:0150089,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.",multiple spine synapse organization,biological_process
88974,GO:0150090,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.","multiple spine synapse organization, single dendrite",biological_process
88975,GO:0150091,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.","multiple spine synapse organization, multiple dendrites",biological_process
88976,GO:0150092,"A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.",regulation of synaptic scaling,biological_process
88977,GO:0150093,"The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.",amyloid-beta clearance by transcytosis,biological_process
88978,GO:0150094,"The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.",amyloid-beta clearance by cellular catabolic process,biological_process
88979,GO:0150098,"Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.",glial cell-neuron signaling,biological_process
88980,GO:0150099,"Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.",neuron-glial cell signaling,biological_process
88981,GO:0150101,"Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.",regulation of microtubule anchoring at centrosome,biological_process
88982,GO:0150102,"Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.",negative regulation of monocyte activation,biological_process
88983,GO:0150103,"A coordinated response of central nervous system (CNS) glial cells-including astrocytes, microglia, and NG2 glia-to injury, infection, or disease, characterized by changes in gene expression, morphology, proliferation, and extracellular matrix production. Reactive gliosis can range from transient glial activation to the formation of a persistent glial scar border.",reactive gliosis,biological_process
88984,GO:0150104,"The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.",transport across blood-brain barrier,biological_process
88985,GO:0150105,"A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.",protein localization to cell-cell junction,biological_process
88986,GO:0150106,"Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.",regulation of protein localization to cell-cell junction,biological_process
88987,GO:0150107,"Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.",positive regulation of protein localization to cell-cell junction,biological_process
88988,GO:0150111,"Any process that modulates the frequency, rate or extent of transepithelial transport.",regulation of transepithelial transport,biological_process
88989,GO:0150115,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.",cell-substrate junction organization,biological_process
88990,GO:0150116,"Any process that modulates the frequency, rate or extent of cell-substrate junction organization.",regulation of cell-substrate junction organization,biological_process
88991,GO:0150117,"Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization.",positive regulation of cell-substrate junction organization,biological_process
88992,GO:0150118,"Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.",negative regulation of cell-substrate junction organization,biological_process
88993,GO:0150119,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.",negative regulation of protein localization to cell-cell junction,biological_process
88994,GO:0150127,"Any process that modulates the frequency, rate or extent of interleukin-33 production.",regulation of interleukin-33 production,biological_process
88995,GO:0150128,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.",negative regulation of interleukin-33 production,biological_process
88996,GO:0150129,"Any process that activates or increases the frequency, rate or extent of interleukin-33 production.",positive regulation of interleukin-33 production,biological_process
88997,GO:0150136,"Any process that modulates the frequency, rate or extent of interleukin-37 production.",regulation of interleukin-37 production,biological_process
88998,GO:0150137,"The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-37 production,biological_process
88999,GO:0150138,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.",negative regulation of interleukin-37 production,biological_process
89000,GO:0150139,"Any process that activates or increases the frequency, rate or extent of interleukin-37 production.",positive regulation of interleukin-37 production,biological_process
89001,GO:0150146,The disaggregation of a cell junction into its constituent components.,cell junction disassembly,biological_process
89002,GO:0150147,The disaggregation of a cell-cell junction into its constituent components.,cell-cell junction disassembly,biological_process
89003,GO:0150151,"Any process that modulates the frequency, rate or extent of interleukin-17A production.",regulation of interleukin-17A production,biological_process
89004,GO:0150152,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.",negative regulation of interleukin-17A production,biological_process
89005,GO:0150153,"Any process that activates or increases the frequency, rate or extent of interleukin-17A production.",positive regulation of interleukin-17A production,biological_process
89006,GO:0150155,"The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.",interleukin-34 production,biological_process
89007,GO:0150157,"Any process that modulates the frequency, rate or extent of interleukin-34 production.",regulation of interleukin-34 production,biological_process
89008,GO:0150158,"Any process that activates or increases the frequency, rate or extent of interleukin-34 production.",positive regulation of interleukin-34 production,biological_process
89009,GO:0150159,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.",negative regulation of interleukin-34 production,biological_process
89010,GO:0150172,"Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.",regulation of phosphatidylcholine metabolic process,biological_process
89011,GO:0150175,"Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.",regulation of phosphatidylethanolamine metabolic process,biological_process
89012,GO:0150189,"Any process that modulates the frequency, rate or extent of interleukin-32 production.",regulation of interleukin-32 production,biological_process
89013,GO:0150190,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.",negative regulation of interleukin-32 production,biological_process
89014,GO:0150191,"Any process that activates or increases the frequency, rate or extent of interleukin-32 production.",positive regulation of interleukin-32 production,biological_process
89015,GO:0150195,"The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.",transport across blood-cerebrospinal fluid barrier,biological_process
89016,GO:0150200,"Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.",regulation of transport across blood-brain barrier,biological_process
89017,GO:0150201,"Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.",positive regulation of transport across blood-brain barrier,biological_process
89018,GO:0150202,"Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.",negative regulation of transport across blood-brain barrier,biological_process
89019,GO:0151001,"A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell.",tuft,cellular_component
89020,GO:0160001,Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.,extrasynaptic signaling via GABA,biological_process
89021,GO:0160002,Binding to a protein upon ADP-ribosylation of the target protein.,ADP-D-ribose modification-dependent protein binding,molecular_function
89022,GO:0160003,Binding to a protein upon mono-ADP-ribosylation of the target protein.,mono-ADP-D-ribose modification-dependent protein binding,molecular_function
89023,GO:0160004,Binding to a protein upon poly-ADP-ribosylation of the target protein.,poly-ADP-D-ribose modification-dependent protein binding,molecular_function
89024,GO:0160005,"A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47.",PAT complex,cellular_component
89025,GO:0160006,An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I.,Fc receptor-mediated immune complex endocytosis,biological_process
89026,GO:0160007,The process in which glutathione is transported from the cytosol into the mitochondrial matrix.,glutathione import into mitochondrion,biological_process
89027,GO:0160008,Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein].,protein decrotonylase activity,molecular_function
89028,GO:0160009,Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] = (2E)-2-butenoate + L-lysyl-[histone].,histone decrotonylase activity,molecular_function
89029,GO:0160010,Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein].,protein de-2-hydroxyisobutyrylase activity,molecular_function
89030,GO:0160011,Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein decrotonylase activity,molecular_function
89031,GO:0160012,Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone] + nicotinamide.,"histone decrotonylase activity, NAD-dependent",molecular_function
89032,GO:0160013,Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.,NAD-dependent protein de-2-hydroxyisobutyrylase activity,molecular_function
89033,GO:0160014,"An extracellular vesicle that is approximately four microns in diameter, released by budding out of cells into the extracellular space, and hypothesized to be a mechanism for disposal of unwanted cellular material including protein aggregates and damaged organelles.",exopher,cellular_component
89034,GO:0160015,"Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium.",platelet rolling,biological_process
89035,GO:0160016,Catalysis of the reaction: a tRNA with a 3' CCA end + 2 CTP + ATP = a tRNA with a 3' CCACCA end + 3 diphosphate.,CCACCA tRNA nucleotidyltransferase activity,molecular_function
89036,GO:0160017,"Any process that modulates the frequency, rate or extent of platelet rolling.",regulation of platelet rolling,biological_process
89037,GO:0160018,"Any process that increases the rate, frequency, or extent of platelet rolling.",positive regulation of platelet rolling,biological_process
89038,GO:0160019,"Any process that decreases the rate, frequency, or extent of platelet rolling.",negative regulation of platelet rolling,biological_process
89039,GO:0160020,"Any process that activates or increases the frequency, rate or extent of ferroptosis.",positive regulation of ferroptosis,biological_process
89040,GO:0160021,"Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome.",maternal-to-zygotic transition of gene expression,biological_process
89041,GO:0160022,The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm.,apocrine secretion,biological_process
89042,GO:0160023,"A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane.",sneeze reflex,biological_process
89043,GO:0160024,"The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone.",Leydig cell proliferation,biological_process
89044,GO:0160025,A sensory perception which causes the desire or reflex to scratch.,sensory perception of itch,biological_process
89045,GO:0160027,The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment.,egg deposition,biological_process
89046,GO:0160028,"Any process that decreases the frequency, rate or extent of a pyroptotic inflammatory response.",negative regulation of pyroptotic inflammatory response,biological_process
89047,GO:0160029,"The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.",kidney cortex tubule cell dedifferentiation,biological_process
89048,GO:0160030,"Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine.",pollen intine formation,biological_process
89049,GO:0160031,"The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together.",endoplasmic reticulum membrane biogenesis,biological_process
89050,GO:0160032,"A protein activation cascade that generates the active Toll receptor ligand and consists of the cascade of enzymatic reactions initiated by extracellular recognition factors, leading to the cleavage of the inactive form of spatzle family of ligands.",Toll receptor ligand protein activation cascade,biological_process
89051,GO:0160033,"Any process that modulates the frequency, rate or extent of the Toll receptor ligand protein activation cascade.",regulation of Toll receptor ligand protein activation cascade,biological_process
89052,GO:0160034,"Any process that activates or increases the frequency, rate or extent of Toll receptor ligand protein activation cascade.",positive regulation of Toll receptor ligand protein activation cascade,biological_process
89053,GO:0160035,"Any process that stops, prevents or reduces the frequency, rate or extent of Toll receptor ligand protein activation cascade.",negative regulation of Toll receptor ligand protein activation cascade,biological_process
89054,GO:0160036,"Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly.",positive regulation of postsynaptic density assembly,biological_process
89055,GO:0160037,"Any process that decreases the rate, frequency, or extent of postsynaptic density assembly.",negative regulation of postsynaptic density assembly,biological_process
89056,GO:0160038,The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain.,somatic sensory system development,biological_process
89057,GO:0160039,Enables the transmembrane transfer of a chloride ion by a channel that opens when the biogenic amine serotonin has been bound by the channel complex or one of its constituent parts. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.,serotonin-gated chloride channel activity,molecular_function
89058,GO:0160040,A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells.,mitocytosis,biological_process
89059,GO:0160041,"The receptor ligand activity of any polypeptide expressed in, and secreted from a neuron.",neuropeptide activity,molecular_function
89060,GO:0160042,"Catalysis of the active transport of purine nucleotides across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.",purine nucleotide uniporter activity,molecular_function
89061,GO:0160043,The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter.,"catecholamine secretion, neurotransmission",biological_process
89062,GO:0160044,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + sulfate(out) = chloride(out) + sulfate(in).,sulfate:chloride antiporter activity,molecular_function
89063,GO:0160045,"A multilamellar subcellular structure formed in the cytoplasm of developing neuron, composed of Tmem240 and Emd proteins.",TMEM240-body,cellular_component
89064,GO:0160046,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + oxalate(in) = chloride(in) + oxalate(out).,oxalate:chloride antiporter activity,molecular_function
89065,GO:0160047,Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H+ + 6-O-phospho-muramyl dipeptide.,muramyl dipeptide kinase activity,molecular_function
89066,GO:0160048,The process of fusing together the edges of a craniofacial suture.,craniofacial suture closure,biological_process
89067,GO:0160049,"Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway.",negative regulation of cGAS/STING signaling pathway,biological_process
89068,GO:0160050,"Binding to xanthine, a purine base.",xanthine binding,molecular_function
89069,GO:0160051,"A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters.",Cyc8(Ssn6)-Tup1 general repressor complex,cellular_component
89070,GO:0160052,"The mitotic cell cycle process in which the nuclear envelope, including nuclear pores, is equally distributed to the two daughter cells during the mitotic cell cycle.",mitotic nuclear envelope segregation,biological_process
89071,GO:0160053,"Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphoseryl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a serine in the active site.",serine-based site-specific recombinase activity,molecular_function
89072,GO:0160054,"The aggregation, arrangement and bonding together of microfibril.",microfibril assembly,biological_process
89073,GO:0160055,"A protein complex composed of at least GAP45 (gliding-associated protein), GAP50 and myosin heavy and light chains. Anchored via GAP50 to the inner membrane complex of motile and invasive forms of apicomplexan parasites and regulates parasite gliding motility and invasion of host cells.",glideosome,cellular_component
89074,GO:0160056,The lipid bilayer surrounding a macropinosome.,macropinosome membrane,cellular_component
89075,GO:0160057,"The process in which a cell becomes capable of differentiating autonomously into a plant endodermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.",plant endodermal cell fate specification,biological_process
89076,GO:0160058,The process in which a relatively unspecialized cell acquires specialized features of a plant endodermal cell.,plant endodermal cell differentiation,biological_process
89077,GO:0160059,Cell death resulting from activation of endogenous cellular processes and occurring as a result of a retinoic acid.,programmed cell death in response to retinoic acid,biological_process
89078,GO:0160060,A homeostatic process in which the drive for sleep increases sleep propensity with prolonged wakefulness.,sleep homeostasis,biological_process
89079,GO:0160061,A homeostatic process by which the sensing of CO2 and/or H+ by the brain leads to appropriate altering in breathing to regulate blood gas and tissue pH.,respiratory chemosensitivity,biological_process
89080,GO:0160062,"The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. Cutin-based cuticle is an extracellular structure composed of a covalently linked macromolecular scaffold of cutin and a variety of organic solvent-soluble lipids that are collectively termed waxes. Such structures are found on the external face of polysaccharide cell walls in land plants.",cutin-based cuticle development,biological_process
89081,GO:0160063,A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions.,multi-pass transmembrane protein insertion into ER membrane,biological_process
89082,GO:0160064,"A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47).",multi-pass translocon complex,cellular_component
89083,GO:0160065,"A protein complex associated with the mitotic spindle pole body during interphase and mitosis and comprises of the proteins of the septation initiation signaling network (SIN) of fission yeast or mitotic exit network (MEN) of budding yeast, organized by two scaffold/adaptor proteins.",SIN/MEN signaling complex,cellular_component
89084,GO:0160066,A SIN signaling complex associated with the old mitotic spindle pole body during interphase and early M-phase and characterised by the presence active ubiquitin ligase (Dma1 in fission yeast) and GTPase activator (Spg1 in fission yeast) to inactivate SIN signaling.,interphase SIN signaling complex,cellular_component
89085,GO:0160067,A SIN signaling complex associated with the new mitotic spindle pole body during anaphase and characterized by the presence activated (GTP bound) GTPase (Spg1 in fission yeast) to activate SIN signaling.,new spindle pole body SIN signaling complex,cellular_component
89086,GO:0160068,"Any process that decreases the rate, frequency or extent of pollen tube guidance towards ovules. This is one mechanism to prevent polytuby, the simultaneous penetration of ovules by multiple pollen tubes.",negative regulation of pollen tube guidance,biological_process
89087,GO:0160069,The regulated release of surfactant by a cell or tissue.,surfactant secretion,biological_process
89088,GO:0160070,A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell.,intracellular borate homeostasis,biological_process
89089,GO:0160071,The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell.,prevention of polyspermy during double fertilization,biological_process
89090,GO:0160072,"The binding activity of a molecule that brings together an ubiquitin ligase and an ubiquitin ligase-substrate adaptor, permitting those molecules to function in a coordinated way.",ubiquitin ligase complex scaffold activity,molecular_function
89091,GO:0160073,"The aggregation, arrangement and bonding together of a set of components to form a Casparian strip, a region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material.",Casparian strip assembly,biological_process
89092,GO:0160074,"An inflammasome complex containing CASP4, known as caspase-11 (Casp11) in mouse, which assembles upon cytosolic lipopolysaccharide-binding and directly activates Gasdermin-D (GSDMD).",non-canonical inflammasome complex,cellular_component
89093,GO:0160075,"The aggregation, arrangement and bonding together of a set of components to form a non-canonical inflammasome complex.",non-canonical inflammasome complex assembly,biological_process
89094,GO:0160076,"Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical inflammasome complex assembly.",negative regulation of non-canonical inflammasome complex assembly,biological_process
89095,GO:0160077,The process by which a single lipid droplet is created from the fusion of two or more lipid droplets.,lipid droplet fusion,biological_process
89096,GO:0160078,"Any process that stops, prevents, or reduces the frequency, rate or extent of lipid droplet fusion.",negative regulation of lipid droplet fusion,biological_process
89097,GO:0160079,Combining with glycine and transmitting the signal across the membrane by changing the activity of intracellular G protein signaling.,G protein-coupled glycine receptor activity,molecular_function
89098,GO:0160080,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + indole(in) = ADP + phosphate + indole(out).,ABC-type indole transporter activity,molecular_function
89099,GO:0160081,Enables the energy-independent facilitated diffusion of iodide through a transmembrane aqueous pore or channel.,iodide channel activity,molecular_function
89100,GO:0160082,Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].,hypoxia-inducible factor-proline dioxygenase activity,molecular_function
89101,GO:0160083,The process in which an activated T cell acquires specialized features of an exhausted T cell.,exhausted T cell differentiation,biological_process
89102,GO:0160086,"A process in which a protein is transported to, or maintained in, a location within a polar microtubule.",protein localization to polar microtubule,biological_process
89103,GO:0160087,The process of removing the majority of the cytoplasm and organelles from a spermatid as it develops into a mature flagellated sperm cell.,spermatid cytoplasm removal during spermiation of flagellated sperm,biological_process
89104,GO:0160089,"A protein adaptor that recognizes and binds an RNA molecule modified by N(7)-methylguanine (m7G), a modification present at internal sites of mRNAs and some non-coding RNAs.",internal N(7)-methylguanine-containing RNA reader activity,molecular_function
89105,GO:0160090,Catalysis of the reaction: a guanosine in mRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine.,internal mRNA (guanine-N7-)-methyltransferase activity,molecular_function
89106,GO:0160091,Formation of circular RNAs (circRNAs) by back-splicing circularization of pre-mRNAs in a spliceosome-dependent process.,spliceosome-depend formation of circular RNA,biological_process
89107,GO:0160092,"A protein-containing complex involved in hemoglobin degradation and detoxification of heme in the food vacuole during the asexual blood stage of a Plasmodium. It is composed of at least falcipains FP2A and/or FP2B, plasmepsins PMII, PMIII/HAP and PMIV, heme detoxifying protein HDP and falcilysin FLN.",hemozoin formation complex,cellular_component
89108,GO:0160093,"The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure.",chordate pharynx development,biological_process
89109,GO:0160094,"The process whose specific outcome is the progression of nematode pharynx over time, from its formation to the mature structure.",nematode pharynx development,biological_process
89110,GO:0160095,"The process whose specific outcome is the progression of insect pharynx over time, from its formation to the mature structure.",insect pharynx development,biological_process
89111,GO:0160096,"The process whose specific outcome is the progression of the nematode pharyngeal muscle over time, from its formation to the mature structure.",nematode pharyngeal muscle development,biological_process
89112,GO:0160097,"Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle, is driven by ATP hydrolysis.",reverse gyrase activity,molecular_function
89113,GO:0160101,Catalysis of the reaction: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine.,tRNA (guanine(10)-N2)-dimethyltransferase activity,molecular_function
89114,GO:0160102,Catalysis of the reaction: guanosine(10) in tRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanine(10)-N2)-methyltransferase activity,molecular_function
89115,GO:0160103,Catalysis of the reaction: guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine = 4 H+ + N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine.,tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity,molecular_function
89116,GO:0160104,Catalysis of the reaction:guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine.,tRNA (guanine(26)-N2)-dimethyltransferase activity,molecular_function
89117,GO:0160105,Catalysis of the reaction: adenosine(22) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(22) in tRNA + S-adenosyl-L-homocysteine.,tRNA (adenine(22)-N1)-methyltransferase activity,molecular_function
89118,GO:0160106,Catalysis of the reaction: adenosine(9) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine.,tRNA (adenine(9)-N1)-methyltransferase activity,molecular_function
89119,GO:0160107,Catalysis of the reaction: adenosine(58) in tRNA + S-adenosyl-L-methionine = H+ + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine.,tRNA (adenine(58)-N1)-methyltransferase activity,molecular_function
89120,GO:0160108,A developmental process whose specific outcome is the progression of a gross anatomical part of an animal over time from an initial condition to a later condition.,animal gross anatomical part developmental process,biological_process
89121,GO:0160109,A developmental process whose specific outcome is the progression of a gross anatomical part of a plant over time from an initial condition to a later condition.,plant gross anatomical part developmental process,biological_process
89122,GO:0160110,A structural network of microtubule inner proteins (MIPs) located inside the lumens of the A and B tubules of the axonemal microtuble doublet that helps stabilize the doublet microtubule.,axonemal microtubule doublet inner sheath,cellular_component
89123,GO:0160111,A structural network of microtubule inner proteins (MIPs) located inside the lumen of the A tubule of the axonemal microtubule doublet that helps stabilize the A tubule.,axonemal A tubule inner sheath,cellular_component
89124,GO:0160112,A structural network of microtubule inner proteins (MIPs) located inside the lumen of the B tubule of the axonemal microtubule doublet that helps stabilize the B tubule.,axonemal B tubule inner sheath,cellular_component
89125,GO:0160113,The structure which joins the B10 protofilament of the B tubule to the A1 protofilament of the A tubule within an axonemal microtubule doublet.,axonemal microtubule doublet inner junction,cellular_component
89126,GO:0160114,The structure which joins the B1 protofilament of the B tubule to the A10 and A11 protofilaments of the A tubule within an axonemal microtubule doublet.,axonemal microtubule doublet outer junction,cellular_component
89127,GO:0160115,"The 3 protofilaments A11, A12, and A13 of the A tubule along with associated inner sheath microtuble inner proteins (MIPs), either in the lumen of the A tubule or of the B tubule, which stabilize these three filiments within the axonemal doublet microtubule. The ribbon protofilaments separate the lumens of the A and B tubules.",axonemal microtubule doublet ribbon,cellular_component
89128,GO:0160117,Catalysis of the reaction: guanosine(6) in tRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanine(6)-N2)-methyltransferase activity,molecular_function
89129,GO:0160118,Catalysis of the reaction: guanosine(7) in tRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine(7) in tRNA + S-adenosyl-L-homocysteine.,tRNA (guanine(7)-N2)-methyltransferase activity,molecular_function
89130,GO:0160119,A programmed cell death process that is induced by intracellular copper accumulation.,cuproptosis,biological_process
89131,GO:0160121,Catalysis of the reaction: 2 3-acyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-acyl-sn-glycero-1-phospho-(3'-acyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol).,bis(monoacylglycero)phosphate synthase activity,molecular_function
89132,GO:0160122,"The process in which a relatively unspecialized cell acquires specialized features of an corneal epithelial cell, any of the cells making up an corneal epithelium.",corneal epithelial cell differentiation,biological_process
89133,GO:0160123,The action of a molecule that contributes to the structural integrity of nuclear lamina.,structural constituent of nuclear lamina,molecular_function
89134,GO:0160124,Binds to and increases the activity of a guanyl nucleotide exchange factor.,guanyl nucleotide exchange factor activator activity,molecular_function
89135,GO:0160125,A gated channel activity that enables the transmembrane transfer of a sodium ion by a channel that opens in response to a change in pH.,pH-gated sodium channel activity,molecular_function
89136,GO:0160126,A gated channel activity that enables the transmembrane transfer of a calcium ion by a channel that opens in response to a change in pH.,pH-gated calcium channel activity,molecular_function
89137,GO:0160127,A process that rescues stalled ribosomes by removing the covalent cross-link between RNA and a protein.,protein-RNA covalent cross-linking repair,biological_process
89138,GO:0160128,Enables the transmembrane transfer of an inorganic ion by a channel that opens in response to a change in proton concentration (pH).,pH-gated monoatomic ion channel activity,molecular_function
89139,GO:0160129,"Catalysis of the cross-link between a protein and a DNA abasic site, forming a thiazolidine linkage between a DNA ring-opened abasic site and the alpha-amino and sulfhydryl substituents of cysteine residue of the protein.",protein-DNA covalent cross-linking activity,molecular_function
89140,GO:0160130,A protein complex that consists of RNA guanine-7 methyltransferase (RNMT) and RNA guanine-7 methyltransferase activating subunit (RAMAC) and is involved in mRNA cap methylation.,mRNA cap methyltransferase RNMT:RAMAC complex,cellular_component
89141,GO:0160131,"The controlled self-propelled movement of a sperm cell from the uterus through the uterotubal junction (UTJ) into the oviduct, where interaction between the sperm and the UTJ acts as a major selective barrier for sperm, allowing only living, motile, uncapacitated, morphologically normal sperm with intact acrosomes to pass from the uterus into the oviduct.",sperm migration through the uterotubal junction,biological_process
89142,GO:0160132,"A cell part that is composed of multifold plasma membrane of the epidermis where it is in direct contact with apical extracellular matrix. Meisosome, or multiple eisome is named because of its superficial similarity to yeast eisosome.",meisosome,cellular_component
89143,GO:0160133,Enables the energy-independent facilitated diffusion of bicarbonate through a transmembrane aqueous pore or channel.,bicarbonate channel activity,molecular_function
89144,GO:0160134,"A protein adaptor activity characterized by the capacity to selectively recognize and interact with RNA molecules in a sequence-specific manner. Entities possessing this activity typically exhibit discerning binding preferences for specific nucleotide sequences within RNA molecules, enabling the identification and engagement of distinct RNA motifs or structural elements. This function is integral to various biological processes, including RNA processing, transport, and regulatory mechanisms, ...",protein-RNA sequence-specific adaptor activity,molecular_function
89145,GO:0160135,"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.",phospholipase C-activating endothelin receptor signaling pathway,biological_process
89146,GO:0160136,Catalysis of the reaction: uridine(516) in 16S rRNA = pseudouridine(516) in 16S rRNA.,16S rRNA pseudouridine(516) synthase activity,molecular_function
89147,GO:0160137,Catalysis of the reaction: uridine(2457) in 23S rRNA = pseudouridine(2457) in 23S rRNA.,23S rRNA pseudouridine(2457) synthase activity,molecular_function
89148,GO:0160138,Catalysis of the reaction: uridine(2604) in 23S rRNA = pseudouridine(2604) in 23S rRNA.,23S rRNA pseudouridine(2604) synthase activity,molecular_function
89149,GO:0160139,Catalysis of the reaction: uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA.,23S rRNA pseudouridine(2605) synthase activity,molecular_function
89150,GO:0160140,Catalysis of the reaction: uridine(1911/1915/1917) in 23S rRNA = pseudouridine(1911/1915/1917) in 23S rRNA.,23S rRNA pseudouridine(1911/1915/1917) synthase activity,molecular_function
89151,GO:0160141,Catalysis of the reaction: uridine(955/2504/2580) in 23S rRNA = pseudouridine(955/2504/2580) in 23S rRNA.,23S rRNA pseudouridine(955/2504/2580) synthase activity,molecular_function
89152,GO:0160142,Catalysis of the reaction: uridine(746) in 23S rRNA = pseudouridine(746) in 23S rRNA.,23S rRNA pseudouridine(746) synthase activity,molecular_function
89153,GO:0160143,Catalysis of the reaction: uridine(2819) in 21S rRNA = pseudouridine(2819) in 21S rRNA.,21S rRNA pseudouridine(2819) synthase activity,molecular_function
89154,GO:0160144,"The series of molecular signals initiated by GDF15 binding to GFRAL coreceptor, triggering RET autophosphorylation and activation, in response to stress.",GDF15-GFRAL signaling pathway,biological_process
89155,GO:0160145,"Any process that stops, prevents or reduces the frequency, rate or extent of GDF15-GFRAL signaling pathway.",negative regulation of GDF15-GFRAL signaling pathway,biological_process
89156,GO:0160147,"Catalysis of the reaction: uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA. Modifies uridine(38), uridine(39) and/or uridine(40) in tRNA.",tRNA pseudouridine(38-40) synthase activity,molecular_function
89157,GO:0160148,Catalysis of the reaction: uridine(55) in tRNA = pseudouridine(55) in tRNA.,tRNA pseudouridine(55) synthase activity,molecular_function
89158,GO:0160149,Catalysis of the reaction: uridine(65) in tRNA = pseudouridine(65) in tRNA.,tRNA pseudouridine(65) synthase activity,molecular_function
89159,GO:0160150,Catalysis of the reaction: uridine(13) in tRNA = pseudouridine(13) in tRNA.,tRNA pseudouridine(13) synthase activity,molecular_function
89160,GO:0160151,Catalysis of the reaction: uridine(32) in tRNA = pseudouridine(32) in tRNA.,tRNA pseudouridine(32) synthase activity,molecular_function
89161,GO:0160152,Catalysis of the reaction: uridine(31) in tRNA = pseudouridine(31) in tRNA.,tRNA pseudouridine(31) synthase activity,molecular_function
89162,GO:0160153,Catalysis of the reaction: uridine(27/28) in mitochondrial tRNA = pseudouridine(27/28) in mitochondrial tRNA.,mitochondrial tRNA pseudouridine(27/28) synthase activity,molecular_function
89163,GO:0160154,Catalysis of the reaction: uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA. Modifies uridine(38) and/or uridine(39) in tRNA.,tRNA pseudouridine(38/39) synthase activity,molecular_function
89164,GO:0160155,"The autophagic process which involves the direct fusion of abnormal, excess or obsolete secretory granules with lysosomes. This pathway is often associated with maintaining homeostasis in endocrine and exocrine cells.",crinophagy,biological_process
89165,GO:0160156,The cellular process that results in the fusion of secretory granules with lysosomes to form crinosomes.,secretory granule-lysosome fusion,biological_process
89166,GO:0160157,"A multi-enzyme complex that catalyzes the oxidative decarboxylation of branched-chain alpha-ketoacids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: branched-chain alpha-ketoacid dehydrogenase (E1, a heterotetramer of two alpha and two beta subunits), dihydrolipoyl transacylase (E2), and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present.",branched-chain alpha-ketoacid dehydrogenase complex,cellular_component
89167,GO:0160159,"Any process that activates or increases the frequency, rate or extent of N-acetylmuramic acid catabolic process.",positive regulation of N-acetylmuramic acid catabolic process,biological_process
89168,GO:0160160,"Any process that activates or increases the frequency, rate or extent of nicotine catabolic process.",positive regulation of nicotine catabolic process,biological_process
89169,GO:0160161,"Any process that activates or increases the frequency, rate or extent of 1,2-propanediol catabolic process.","positive regulation of 1,2-propanediol catabolic process",biological_process
89170,GO:0160162,"The series of molecular signals initiated by the binding of the cell surface receptor CD27 to its physiological ligand CD70, and ending with the regulation of a downstream cellular process, e.g. transcription.",CD27 signaling pathway,biological_process
89171,GO:0160163,Catalysis of the reaction: H+ + NADPH + S-nitrosoglutathione = NADP+ + S-(hydroxysulfenamide)glutathione.,S-nitrosoglutathione reductase (NADPH) activity,molecular_function
89172,GO:0160164,"Any process that stops, prevents or reduces the frequency, rate or extent of chromatin looping.",negative regulation of chromatin looping,biological_process
89173,GO:0160165,The process of regulating the proliferation and elimination of CD8-positive alpha-beta T cells such that the total number of CD8-positive alpha-beta T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.,"CD8-positive, alpha-beta T cell homeostasis",biological_process
89174,GO:0160166,Catalysis of the reaction: 2-oxoadipate + H+ + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] = CO2 + N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase].,2-oxoadipate dehydrogenase activity,molecular_function
89175,GO:0160167,"A multi-enzyme complex that catalyzes the oxidative decarboxylation of 2-oxoadipate to glutaryl-CoA, thereby acting in the final step of lysine and tryptophan catabolism in mitochondria. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: 2-oxoadipate dehydrogenase (E1), dihydrolipoamide S-glutaryltransferase (E2) and dihydrolipoamide dehydrogenase (E3).",oxoadipate dehydrogenase complex,cellular_component
89176,GO:0160168,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=9 symmetry. The T=9 capsid is composed of 12 pentameric and 80 hexameric capsomeres.,T=9 icosahedral viral capsid,cellular_component
89177,GO:0160169,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=21 or pseudo T=21 symmetry.,T=21/pseudo21 icosahedral capsid,cellular_component
89178,GO:0160170,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=27 or pseudo T=27 symmetry.,T=27/pseudo27 icosahedral capsid,cellular_component
89179,GO:0160171,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=28 symmetry.,T=28 icosahedral capsid,cellular_component
89180,GO:0160172,The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=31 or pseudo T=31 symmetry.,T=31/pseudo31 icosahedral capsid,cellular_component
89181,GO:0160173,Enables the transfer of histamine from one side of a membrane to the other.,histamine transmembrane transporter activity,molecular_function
89182,GO:0160174,A cellular developmental process by which the outer layer of the cell (the cortex) rotates relative to the inner cytoplasm.,cortical rotation,biological_process
89183,GO:0160175,"The developmental process in which a somatic muscle attaches to the chitin-based cuticle. In insects, this may occur via a specialized epithelial cell adherence to the chitinous extracellular matrix and to muscle cells through their basement membrane.",somatic muscle attachment to chitin-based cuticle,biological_process
89184,GO:0160176,The directed movement of magnesium ion from cytosol to endoplasmic reticulum.,magnesium ion transport from cytosol to endoplasmic reticulum,biological_process
89185,GO:0160177,Any process that activates or increases the rate which autophagosomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects).,positive regulation of autophagosome-lysosome fusion,biological_process
89186,GO:0160178,Catalysis of the transport of a dipeptide across a membrane; transport is independent of the movement of any other molecular species.,dipeptide uniporter activity,molecular_function
89187,GO:0160179,A process in which iron is taken up from the contents of the intestine.,intestinal iron absorption,biological_process
89188,GO:0160181,The chemical reactions and pathways resulting in the formation of piperine.,piperine biosynthetic process,biological_process
89189,GO:0160182,Catalysis of the reaction: a quinol + nitrate = a quinone + H2O + nitrite.,nitrate reductase (quinone) activity,molecular_function
89190,GO:0160183,The binding activity of a molecule that brings together a target membrane and an autophagosome membrane during autophagy.,autophagosome-membrane adaptor activity,molecular_function
89191,GO:0160184,"The directed movement of substance through the space in between adjacent cells, rather than through the cells themselves.",paracellular transport,biological_process
89192,GO:0160185,Binds to and increases the activity of the enzyme phospholipase C.,phospholipase C activator activity,molecular_function
89193,GO:0160186,"Binds to and stops, prevents or reduces the activity of the enzyme phospholipase C.",phospholipase C inhibitor activity,molecular_function
89194,GO:0160187,"Enables size- and charge-selective transport of solutes through a tight junction barrier paracellularly, across the epithelium.",paracellular tight junction channel activity,molecular_function
89195,GO:0160189,An organelle membrane contact site between peroxisomal membrane and mitochondrial outer membrane.,peroxisomal-mitochondrial contact site,cellular_component
89196,GO:0160190,"The binding activity of a molecule that brings together the peroxisome membrane and the mitochondrial outer membrane, establishing the localization of the peroxisome close to the mitochondrion.",peroxisome-mitochondrion membrane tether activity,molecular_function
89197,GO:0160191,Catalysis of the reaction: a C28-steroid + O2 + reduced NADPH--hemoprotein reductase = a (22S)-22-hydroxy C28-steroid + H+ + H2O + oxidized NADPH--hemoprotein reductase. Also catalyzes the C-22 hydroxylation of a variety of C27 and C29 steroids.,steroid 22S-hydroxylase activity,molecular_function
89198,GO:0160192,A process of exocytosis that uses the autophagy machinery to facilitate secretion of the cytosolic cargo such as leaderless cytosolic proteins which cannot enter the conventional secretory pathway operating via the endoplasmic reticulum and the Golgi apparatus.,autophagosome-dependent secretion,biological_process
89199,GO:0160193,"Binds to and stops, prevents or reduces the activity of L-lactate dehydrogenase.",L-lactate dehydrogenase inhibitor activity,molecular_function
89200,GO:0160194,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a sensory hair cell stereocilium bundle.",stereocilium bundle organization,biological_process
89201,GO:0160195,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C/protein kinase C signal transduction.",negative regulation of phospholipase C/protein kinase C signal transduction,biological_process
89202,GO:0160196,"Catalysis of the reaction: a di-trans,poly-cis-polyprenol + NAD+ = a di-trans,poly-cis-polyprenal + NADH + H+.",polyprenol dehydrogenase (NAD+) activity,molecular_function
89203,GO:0160197,"Catalysis of the reaction: a di-trans,poly-cis-dolichol + NADP+ = a di-trans,poly-cis-dolichal + NADPH + H+.",dolichal reductase (NADPH) activity,molecular_function
89204,GO:0160198,"Catalysis of the reaction: ditrans,polycis-polyprenal+ H+ + NADPH = ditrans,polycis-dolichal+ NADP.",polyprenal reductase activity,molecular_function
89205,GO:0160199,"Any process that activates or increases the frequency, rate or extent of 7-methylguanosine mRNA capping.",positive regulation of 7-methylguanosine mRNA capping,biological_process
89206,GO:0160201,"A membrane-bounded organelle found in a microsporidian spore,  that swells with water, and exerts pressure to rupture the polar cap and evert the polar tube through which the sporoplasm escapes to infect the host.",polaroplast,cellular_component
89207,GO:0160202,A structural component of the microsporidian spore's invasion apparatus that is located at the anterior end of the spore and serves to attach the polar tube to the inside of the spore wall.,polar tube anchoring disc,cellular_component
89208,GO:0160203,The import of small cysteine-containing proteins from the cytosol across the outer mitochondrial membrane via the TOM complex driven by oxidative folding.,protein import into the intermembrane space via the disulfide relay system,biological_process
89209,GO:0160204,"The binding activity of a molecule that brings together two mitochondrion membranes via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.",mitochondrion-mitochondrion outer membrane tether activity,molecular_function
89210,GO:0160205,Catalysis of the reaction: [ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 2 H(+) + 3 H2O + nicotinamide.,cysteine-dependent adenosine diphosphate thiazole synthase activity,molecular_function
89211,GO:0160206,Catalysis of the reaction: cytidine(32)/uridine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methyluridine(32) in tRNA + H+ + S-adenosyl-L-homocysteine.,tRNA (cytidine(32)/uridine(32)-2'-O-ribose)-methyltransferase activity,molecular_function
89212,GO:0160207,"Any process that activates or increases the frequency, rate or extent of androgen receptor signaling.",positive regulation of androgen receptor signaling pathway,biological_process
89213,GO:0160208,A Golgi-derived organelle that forms in primary spermatocytes during spermatogenesis of some nematodes including C. elegans. This 'double organelle' consists of a fibrous body containing major sperm protein and a membranous organelle that envelops the developing fibrous body.,fibrous body-membranous organelle,cellular_component
89214,GO:0160209,"A protein-containing complex that contains the fragile X mental retardation protein (FMRP) and cytoplasmic FMRP Interacting protein 1 (CYIFIP1), and is capable of inhibiting translation initiation by binding to the eIF4F complex.",FMRP-CYFIP1 complex,cellular_component
89215,GO:0160210,Catalysis of the reaction: L-serine + succinyl-CoA = CoA + O-succinyl-L-serine.,L-serine O-succinyltransferase activity,molecular_function
89216,GO:0160211,Any of the lipid bilayers that surround an apicoplast and form the apicoplast envelope.,apicoplast membrane,cellular_component
89217,GO:0160212,Enables the transmembrane transfer of a cation by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.,glycine-gated cation channel activity,molecular_function
89218,GO:0160213,"A beta-arrestin-dependent signaling pathway initiated by a dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.",beta-arrestin-dependent dopamine receptor signaling pathway,biological_process
89219,GO:0160214,"The binding activity of a molecule that brings together a plasma membrane with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication.",endoplasmic reticulum-plasma membrane adaptor activity,molecular_function
89220,GO:0160215,"Catalysis of the reaction: R-CO-X + H2O = R-COOH + HX, hydrolysis of an acyl group or groups from a substrate molecule.",deacylase activity,molecular_function
89221,GO:0160216,Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] = (S)-lactate + L-lysyl-[protein].,protein lysine delactylase activity,molecular_function
89222,GO:0160217,"Any process that stops, prevents or reduces the frequency, rate or extent of transcription initiation-coupled chromatin remodeling.",negative regulation of transcription initiation-coupled chromatin remodeling,biological_process
89223,GO:0160218,"Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.",negative regulation of pyruvate decarboxylation to acetyl-CoA,biological_process
89224,GO:0160219,The lipid bilayer surrounding the cortical endoplasmic reticulum.,cortical endoplasmic reticulum membrane,cellular_component
89225,GO:0160220,Catalysis of the reaction: (R)-lactate + ATP + D-alanine = ADP + D-alanyl-(R)-lactate + phosphate.,D-alanine-(R)-lactate ligase activity,molecular_function
89226,GO:0160221,"A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of Rho activity. Rho is a family of small (~21 kDa) signaling G proteins that include RhoA, Cdc42, and Rac1.",Rho-activating G protein-coupled receptor signaling pathway,biological_process
89227,GO:0160222,Catalysis of the reaction: ATP + D-alanine + D-serine = ADP + D-alanyl-D-serine + H+ + phosphate.,D-alanine-D-serine ligase activity,molecular_function
89228,GO:0160223,A specialized membranous structure that extends from the photosynthetic thylakoid membrane into and transverses the matrix of a pyrenoid.,pyrenoid tubule,cellular_component
89229,GO:0160224,Catalysis of the reaction: a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzoquinone + NADH + O2 = a 3-demethylubiquinone + NAD+ + H2O.,3-demethoxyubiquinone 3-hydroxylase (NADH) activity,molecular_function
89230,GO:0160225,Unwinding G-quadruplex structures in nucleic acids. A G-quadruplex is a specialized structure formed in DNA/RNA when sequences rich in guanine (G) assemble into a unique four-stranded arrangement.,G-quadruplex unwinding activity,molecular_function
89231,GO:0160226,An oligosaccharyltransferase complex that contains STT3A as the catalytic subunit.,oligosaccharyltransferase complex A,cellular_component
89232,GO:0160227,An oligosaccharyltransferase complex that contains STT3B as the catalytic subunit.,oligosaccharyltransferase complex B,cellular_component
89233,GO:0160228,Enables the transmembrane transfer of a sodium ion by a channel that opens when bile acid has been bound by the channel complex or one of its constituent parts.,bile acid-gated sodium channel activity,molecular_function
89234,GO:0160229,"The binding activity of a molecule that brings together a peroxisome membrane and an ER membrane, either via membrane lipid binding or by interacting with a membrane protein.",peroxisome-endoplasmic reticulum membrane tether activity,molecular_function
89235,GO:0160230,Catalysis of the reaction: guanosine in U6 snRNA + S-adenosyl-L-methionine = H+ + N(2)-methylguanosine in U6 snRNA + S-adenosyl-L-homocysteine.,U6 snRNA (guanine-N(2))-methyltransferase activity,molecular_function
89236,GO:0160231,"An actin-based cell projection extending laterally from the basolateral membrane of tuft cells in epithelial tissues, including the intestinal epithelium. These thin projections, typically 3-4 per cell and up to 3 micron long, directly contact the nuclei of adjacent epithelial cells, potentially facilitating intercellular communication and molecular exchange.",cytospinule,cellular_component
89237,GO:0160232,A protein complex containing Integrator and protein phosphatase 2A core enzyme (PP2A-AC) that stably associates with the C-terminus of RNA polymerase II and promotes premature RNA polymerase II transcription termination.,INTAC complex,cellular_component
89238,GO:0160233,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of valine.",valine sensor activity,molecular_function
89239,GO:0160234,"The aggregation, arrangement and bonding together of a set of components to form the integrator complex.",integrator complex assembly,biological_process
89240,GO:0160236,"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + taurine + GTP + H2O + uridine34 in tRNA + A = 7,8-dihydrofolate + GDP + phosphate + 5-taurinomethyluridine34 in tRNA + H+ + AH2.",tRNA 5-taurinomethyluridine synthase activity,molecular_function
89241,GO:0160237,Catalysis of the reaction: D-alanyl-D-alanine + H2O = 2 D-alanine.,D-Ala-D-Ala dipeptidase activity,molecular_function
89242,GO:0160238,Catalysis of the reaction: reduced [NADPH-hemoprotein reductase] + O2 + a long-chain fatty aldehyde = oxidized [NADPH-hemoprotein reductase] + CO2 + H2O + H+ + a long-chain alkane.,long-chain fatty aldehyde oxidative decarbonylase activity,molecular_function
89243,GO:0160239,"A transcription halt following transcription initiation but prior to elongation, during which RNA polymerase II pauses approximately 20-60 nucleotides downstream of the transcriptional start site before proceeding into productive elongation. Transcription pausing starts following phosphorylation of the C-terminal domain (CTD) of RNA polymerase II subunit POLR2A at Ser-5 and stops following phosphorylation of POLR2A by the P-TEFb complex.",transcription pausing by RNA polymerase II,biological_process
89244,GO:0160240,A process that promotes premature RNA polymerase II transcription termination of transcripts that are unfavorably configured for transcriptional elongation by releasing RNA polymerase II from bound DNA or promoting RNA polymerase II degradation.,RNA polymerase II transcription initiation surveillance,biological_process
89245,GO:0160241,Catalysis of the reaction: a cardiolipin + NAD+ = a diphosphatidylglycerone + NADH + H+.,cardiolipin dehydrogenase (NAD+) activity,molecular_function
89246,GO:0160242,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + NAD+ = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerone) + NADH + H+.",phosphatidylglycerol dehydrogenase (NAD+) activity,molecular_function
89247,GO:0160243,Catalysis of the removal of a methyl group from a modified lysine residue of the histone H1 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.,histone H1 demethylase activity,molecular_function
89248,GO:0160244,"The directed movement of sulfite from inside of a cell, across the plasma membrane and into the extracellular region.",sulfite export across plasma membrane,biological_process
89249,GO:0160245,Any process that reduces or removes the toxicity of sulfite. These include transport of sulfite away from sensitive areas and to compartments or complexes whose purpose is sequestration of sulfite.,detoxification of sulfite,biological_process
89250,GO:0160246,Catalysis of the reaction: 2 oxidized [2Fe-2S]-[protein] + NADPH = 2 reduced [2Fe-2S]-[protein] + NADP+ + H+.,NADPH-iron-sulfur [2Fe-2S] protein oxidoreductase activity,molecular_function
89251,GO:0160247,"The binding activity of a molecule that brings together a cargo, targeted for degradation via autophagy, to a phagophore.",autophagy cargo adaptor activity,molecular_function
89252,GO:0160248,Catalysis of the reaction: guanosine(27) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(27) in tRNA + 2 S-adenosyl-L-homocysteine.,tRNA (guanine(27)-N2)-dimethyltransferase activity,molecular_function
89253,GO:0160253,The chemical reactions and pathways resulting in the formation of tRNA queuosine(34) from guanosine triphosphate (GTP).,de novo tRNA queuosine(34) biosynthetic process,biological_process
89254,GO:0160254,The chemical reactions and pathways resulting in the formation of tRNA queuosine(34) by salvaging available queuosine or precursors of queuosine (preQ0 or preQ1).,tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors,biological_process
89255,GO:0160255,The chemical reactions and pathways resulting in the formation of tRNA queuosine(34) by salvaging available queuine.,tRNA queuosine(34) biosynthetic process from salvaged queuine,biological_process
89256,GO:0160256,The process in which L-lysine is transported from the cytosol into the mitochondrial matrix.,L-lysine transmembrane import into the mitochondrion,biological_process
89257,GO:0160257,Any process involved in the activation of any of the steps of the granzyme K pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.,"complement activation, GZMK pathway",biological_process
89258,GO:0160258,An organelle membrane contact site between the endoplasmic reticulum (ER) membrane and the trans-Golgi network (TGN) membrane.,endoplasmic reticulum-trans-Golgi network membrane contact site,cellular_component
89259,GO:0160259,A membrane contact site between the endoplasmic reticulum (ER) membrane and the lipid droplet.,endoplasmic reticulum membrane-lipid droplet contact site,cellular_component
89260,GO:0160260,Catalysis of the reaction: L-asparaginyl-[protein] + H2O = L-aspartyl-[protein] + NH4+.,protein asparagine deamidase activity,molecular_function
89261,GO:0160261,Catalysis of the reaction: histone H1 L-asparagine + H2O = histone H1 L-aspartate + NH4+.,histone H1 asparagine deamidase activity,molecular_function
89262,GO:0160262,Catalysis of the reaction: acetyl-CoA + histone H1 = CoA + acetyl-histone H1.,histone H1 acetyltransferase activity,molecular_function
89263,GO:0160263,Catalysis of the reaction: acetyl-CoA + histone H1 L-lysine (position 75) = CoA + histone H1 N6-acetyl-L-lysine (position 75).,histone H1K75 acetyltransferase activity,molecular_function
89264,GO:0160264,Catalysis of the reaction: histone H1 L-asparagine [positions 76 and 77] + H2O = histone H1 L-aspartate [positions 76 and 77] + NH4+.,histone H1N76/N77 asparagine deamidase activity,molecular_function
89265,GO:0160265,Catalysis of the transfer of a alpha-D-glucose residue from UDP-alpha-D-glucose to the fucose residue of a fucosylated protein acceptor.,O-fucosylpeptide 3-beta-glucosyltransferase activity,molecular_function
89266,GO:0160266,"A biological phase of reproductive dormancy characterized by the temporary cessation of reproductive cyclicity, marked by the absence of ovarian follicular development, estrous behavior, and ovulation. This phase represents a period of sexual quiescence between estrous cycles or breeding seasons.",anestrus phase,biological_process
89267,GO:0160267,A histone reader that recognizes a histone H1 monomethylated at lysine 26.,histone H1K26me1 reader activity,molecular_function
89268,GO:0160268,A histone reader that recognizes a histone H1 dimethylated at lysine 26.,histone H1K26me2 reader activity,molecular_function
89269,GO:0160269,The regulated release of sweat from the sweat glands.,sweat secretion,biological_process
89270,GO:0160270,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out). This reaction results in the exchange of phosphatidylserine (PS) for phosphatidylinositol-4-phosphate (PI(4)P) between membranes.",phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity,molecular_function
89271,GO:0160271,"A protein complex that directly interacts with mRNAs and Rab5, functions as a Rab5 effector, recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction, is composed of five subunits, TBCK, PPP1R21, FERRY3, CRYZL1 and GATD1 with a ratio of 1:2:1:2:4, respectively.",FERRY complex,cellular_component
89272,GO:0160272,"Catalysis of the reaction: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + 2 H2O = a 3'-end ribonucleotide-RNA + phosphate + H+.","RNA 2',3'-cyclic phosphatase activity",molecular_function
89273,GO:0160273,Catalysis of the reaction: H2O + a 3'-end 2'-phospho-ribonucleotide-RNA = a 3'-end ribonucleotide-RNA + phosphate.,RNA 2'-phosphatase activity,molecular_function
89274,GO:0160274,"The process in which a white fat cell acquires specialized features of a beige adipocyte. Beige adipocytes reside within white adipose tissue and can be induced to produce heat in response to cold exposure or certain stimuli, resembling brown adipocytes.",beige fat cell differentiation,biological_process
89275,GO:0160275,"Any process that stops, prevents or reduces the frequency, rate or extent of white fat cell differentiation.",negative regulation of white fat cell differentiation,biological_process
89276,GO:0160276,"Any process that stops, prevents or reduces the frequency, rate or extent of beige fat cell differentiation.",negative regulation of beige fat cell differentiation,biological_process
89277,GO:0160277,"The leaflet of the cis-Golgi cisternae membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where glycosylation and lumen-facing cargo recognition occur.",lumenal side of cis-Golgi cisternae membrane,cellular_component
89278,GO:0160278,"The leaflet of the cis-Golgi cisternae membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site of interactions with cytosolic proteins, including those involved in vesicle budding, membrane tethering, and lipid or protein trafficking.",cytoplasmic side of cis-Golgi cisternae membrane,cellular_component
89279,GO:0160279,"The leaflet of the medial-Golgi cisternae membrane that faces the cytoplasm,including any protein embedded in, attached to, or peripherally associated with it. This is the site of interactions with cytosolic proteins involved in membrane trafficking, vesicle docking, and cargo sorting.",cytoplasmic side of medial-Golgi cisterna membrane,cellular_component
89280,GO:0160280,"The leaflet of the medial-Golgi cisternae membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where protein glycosylation occur.",lumenal side of medial-Golgi cisterna membrane,cellular_component
89281,GO:0160281,"The leaflet of the trans-Golgi network membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site of interaction where cytoplasmic proteins interact with proteins involved in vesicle formation and targeting.",cytoplasmic side of trans-Golgi network membrane,cellular_component
89282,GO:0160282,"The leaflet of the trans-Golgi network membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it.",lumenal side of trans-Golgi network membrane,cellular_component
89283,GO:0160283,Enables the transfer of queuine from one side of a membrane to the other according to the reaction: queuine(out) = queuine(in).,queuine transmembrane transporter activity,molecular_function
89284,GO:0160284,"The directed movement of queuine from outside of a cell, across the plasma membrane and into the cytosol.",queuine import across plasma membrane,biological_process
89285,GO:0160286,Enables the transfer of queuosine from one side of a membrane to the other according to the reaction: queuosine(out) = queuosine(in).,queuosine transmembrane transporter activity,molecular_function
89286,GO:0160287,"The directed movement of queuosine from outside of a cell, across the plasma membrane and into the cytosol.",queuosine import across plasma membrane,biological_process
89287,GO:0160288,"The leaflet of the trans-Golgi cisternae membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site where vesicle formation, and cargo sorting towards post-Golgi destinations such as endosomes, lysosomes and the plasma membrane occur.",cytoplasmic side of trans-Golgi cisterna membrane,cellular_component
89288,GO:0160289,"The leaflet of the trans-Golgi cisternae membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where the final steps of glycan processing, proteolytic modification, and cargo maturation prior to sorting at the trans-Golgi network occur.",lumenal side of trans-Golgi cisternae membrane,cellular_component
89289,GO:0160290,Catalysis of the reaction: 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 2-oxoglutarate + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 succinate + 2 CO2 + H2O.,2-oxoglutarate-dependent tRNA 5-methylcytidine formyltransferase activity,molecular_function
89290,GO:0160291,"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + cholesterol(in) = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + cholesterol(out). This reaction results in the exchange of cholesterol for phosphatidylinositol-4-phosphate (PI(4)P) between membranes.",phosphatidylinositol-4-phosphate-cholesterol exchange activity,molecular_function
89291,GO:0160292,"A bacterial protein complex consisting of six subunits, NqrABCDEF, encoded by the nqr operon, which catalyzes electron transfer from NADH to ubiquinone in the respiratory chain coupled with the transport of sodium ions from the cytoplasm to the periplasm.",sodium-translocating NADH:quinone reductase complex,cellular_component
89292,GO:0160293,"The aggregation, arrangement and bonding together of a set of components to form a sodium-translocating NADH-quinone reductase complex.",sodium-translocating NADH-quinone reductase complex assembly,biological_process
89293,GO:0160295,"A protein complex involved in mitochondrial respiratory chain complex I (MCI) assembly. The mitochondrial complex I intermediate assembly (MCIA) complex is an inner mitochondrial membrane complex required for the aggregation, arrangement and bonding together of the subunits of the ND2-module of MCI. In humans, the MCIA complex is formed from NDUFAF1, ACAD9, ECSIT, TMEM126B, TMEM186 and COA1.",mitochondrial complex I intermediate assembly complex,cellular_component
89294,GO:0160296,"A translation initiation factor activity that enables the recognition and binding to the 7-methylguanosine cap structure at the 5' end of eukaryotic mRNAs, promoting ribosome recruitment and assembly and translation initiation in a cap-dependent manner.",cap-dependent translation initiation factor activity,molecular_function
89295,GO:0160297,"A translation initiation factor activity that enables interaction with internal ribosome entry sites (IRESs) located within mRNA, promoting ribosome recruitment and assembly at internal initiation sites and translation initiation independent of the 5' cap structure.",IRES-mediated translation initiation factor activity,molecular_function
89296,GO:0160298,"Catalysis of the reaction: 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + GTP + H+ = guanylylpyridinol + diphosphate.",pyridinol guanylyltransferase activity,molecular_function
89297,GO:0160300,"The chemical reactions and pathways resulting in the formation of iron-guanylylpyridinol cofactor, in which mononuclear Fe(II) is ligated with a pyridinol and two CO ligands.",iron-guanylylpyridinol cofactor biosynthetic process,biological_process
89298,GO:0160301,Catalysis of the reaction: guanylylpyridinol + ATP + H+ = guanylylpyridinol-AMP + diphosphate.,guanylylpyridinol adenylase activity,molecular_function
89299,GO:0160302,"Catalysis of the reaction: 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol + S-adenosyl-L-methionine = 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + S-adenosyl-L-homocysteine + H+.",6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity,molecular_function
89300,GO:0160303,The process by which proteins are transported from the periplasmic space across the outer membrane of Bacteroidota bacteria via the type IX secretion system (T9SS).,protein secretion by the type IX secretion system,biological_process
89301,GO:0160304,Catalysis of the reaction: 4-vinylphenol + S-adenosyl-L-methionine = 4-vinylanisole + S-adenosyl-L-homocysteine + H+.,4-vinylphenol methyltransferase activity,molecular_function
89302,GO:0160305,The chemical reactions and pathways resulting in the formation of 4-vinylanisole. 4-vinylanisole derived from food plant phenylalanin is the aggregation pheromone specifically released by gregarious migratory locusts.,4-vinylanisole biosynthetic process,biological_process
89303,GO:0160306,"A social behavior in which multiple individuals of the same animal species coordinate their movement in close spatial proximity, forming a dynamic aggregation typically characterized by collective motion, cohesion, and mutual responsiveness among members of the group.",swarm social behavior,biological_process
89304,GO:0160307,The chemical reactions and pathways resulting in the formation of protein.,protein biosynthetic process,biological_process
89305,GO:0160308,Catalysis of the reaction: FAD + succinate + H+ = fumarate + FADH2.,succinate dehydrogenase (FAD) activity,molecular_function
89306,GO:0160309,"A protein complex that promotes the recycling of internalized transmembrane proteins from endosomes back to the plasma membrane. The commander complex consists of the CCC (COMMD/CCDC22/CCDC93) subcomplex and the retriever subcomplex. In human, the CCC subcomplex consists of COMMD1, COMMD2, COMMD3, COMMD4, COMMD5, COMMD6, COMMD7, COMMD8, COMMD9, COMMD10, CCDC22 and CCDC93 and the retriever complex consists of VPS26C, VPS29 and VPS35L.",commander complex,cellular_component
89307,GO:0160310,The active transport of dopamine neurotransmitters into a synaptic vesicle.,dopamine loading into synaptic vesicle,biological_process
89308,GO:0160311,The active transport of tyramine neurotransmitters into a synaptic vesicle.,tyramine loading into synaptic vesicle,biological_process
89309,GO:0160312,The active transport of octopamine neurotransmitters into a synaptic vesicle.,octopamine loading into synaptic vesicle,biological_process
89310,GO:0160313,A membrane-bounded vesicle that is located within the lumen of an endosome.,endosomal intralumenal vesicle,cellular_component
89311,GO:0160314,The lipid bilayer surrounding an intraluminal vesicle within an endososome.,endosomal intralumenal vesicle membrane,cellular_component
89312,GO:0160315,The volume enclosed by the membrane of an intraluminal vesicle within an endosome.,endosomal intralumenal vesicle lumen,cellular_component
89313,GO:0160316,A membrane-bounded vesicle that is located within the lumen of an endolysosome.,endolysosomal intralumenal vesicle,cellular_component
89314,GO:0160317,The lipid bilayer surrounding an intraluminal vesicle within an endolysosome.,endolysosomal intralumenal vesicle membrane,cellular_component
89315,GO:0160318,The volume enclosed by the membrane of an intraluminal vesicle within an endolysosome.,endolysosomal intralumenal vesicle lumen,cellular_component
89316,GO:0160319,Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O.,lipoyl-dependent peroxiredoxin activity,molecular_function
89317,GO:0160321,"The binding activity of a protein that directly mediates the stable attachment of a transport vesicle to a target membrane, bringing the two membranes into close apposition.",vesicle docking activity,molecular_function
89318,GO:0170001,Enables the transfer of ergothioneine from one side of a membrane to the other.,ergothioneine transmembrane transporter activity,molecular_function
89319,GO:0170002,A sodium-specific negative tropism that is crucial for surviving and thriving under high salinity.,halotropism,biological_process
89320,GO:0170003,Enables the transfer of heme B from one side of a membrane to the other.,heme B transmembrane transporter activity,molecular_function
89321,GO:0170004,Enables the transfer of lipoate from one side of a membrane to the other.,lipoate transmembrane transporter activity,molecular_function
89322,GO:0170005,Binds to and increases the activity of cyclic nucleotide phosphodiesterase.,cyclic nucleotide phosphodiesterase activator activity,molecular_function
89323,GO:0170006,The process in which lipoate is transported across a membrane.,lipoate transmembrane transport,biological_process
89324,GO:0170007,"The binding activity of a molecule that brings together a lipid droplet with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication.",endoplasmic reticulum-lipid droplet tether activity,molecular_function
89325,GO:0170008,Binds to and increases the activity of mRNA phosphatase.,mRNA phosphatase activator activity,molecular_function
89326,GO:0170009,"The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication.",endoplasmic reticulum-organelle membrane tether activity,molecular_function
89327,GO:0170010,A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.,nonsense-mediated decay complex,cellular_component
89328,GO:0170011,A molecule that recognizes stalled ribosomes and initiates a signaling response.,stalled ribosome sensor activity,molecular_function
89329,GO:0170012,Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide.,histone H3K18 decrotonylase activity,molecular_function
89330,GO:0170013,A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.,channel complex,cellular_component
89331,GO:0170014,"A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human.",ankyrin-1 complex,cellular_component
89332,GO:0170015,Combining with carbon dioxide to initiate a change in cell activity.,carbon dioxide receptor activity,molecular_function
89333,GO:0170016,"The binding activity of a molecule that brings together an endosome membrane and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange.",endoplasmic reticulum-endosome tether activity,molecular_function
89334,GO:0170020,Enables the transmembrane transfer of an ion by a channel that opens when a specific odorant has been bound by the channel complex or one of its constituent parts.,ionotropic olfactory receptor activity,molecular_function
89335,GO:0170021,Enables the transmembrane transfer of an ion by a channel that opens when a soluble compound has been bound by the channel complex or one of its constituent parts.,ionotropic taste receptor activity,molecular_function
89336,GO:0170022,Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts.,ionotropic bitter taste receptor activity,molecular_function
89337,GO:0170023,Enables the transmembrane transfer of an ion by a channel that opens when a specific soluble sweet compound has been bound by the channel complex or one of its constituent parts.,ionotropic sweet taste receptor activity,molecular_function
89338,GO:0170027,"An outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis. In humans, it contains the subunits SKA1, SKA2 and SKA3.",SKA complex,cellular_component
89339,GO:0170036,The directed movement of substances from the cytosol into the mitochondrion.,import into the mitochondrion,biological_process
89340,GO:0170037,The directed movement of substances from the mitochondrion to the cytosol.,export from the mitochondrion,biological_process
89341,GO:0170038,"The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.",proteinogenic amino acid biosynthetic process,biological_process
89342,GO:0170039,"The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.",proteinogenic amino acid metabolic process,biological_process
89343,GO:0170040,"The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.",proteinogenic amino acid catabolic process,biological_process
89344,GO:0170041,The chemical reactions and pathways involving non-proteingenic amino acids.,non-proteinogenic amino acid metabolic process,biological_process
89345,GO:0170043,The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids.,non-proteinogenic amino acid biosynthetic process,biological_process
89346,GO:0170044,The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids.,non-proteinogenic amino acid catabolic process,biological_process
89347,GO:0170045,Enables the transfer of isopentenyl pyrophosphate from one side of a membrane to the other.,isopentenyl pyrophosphate transmembrane transporter activity,molecular_function
89348,GO:0170046,The process in which isopentenyl pyrophosphate is transported across a membrane into the mitochondrion.,isopentenyl pyrophosphate import into mitochondrion,biological_process
89349,GO:0170047,A protein coat that surrounds nucleic acid to form a structure similar to a virus capsid. Virus-like capsids are non-infectious and are encoded by endogenous (non-viral) genes. Fly and tetrapod Arc (ancestrally-related to retrotransposon Gag) are examples of proteins that can self-assemble into capsid-like structures which encapsulate Arc mRNA and mediate the intercellular transmission of RNA.,virus-like capsid,cellular_component
89350,GO:0170048,The directed import of D-alanine from the extracellular region across the plasma membrane and into the cytosol.,D-alanine import across plasma membrane,biological_process
89351,GO:0170049,"A ribonucleoprotein complex consisting of a box C/D type snRNA and three (Archaea) or four (Eukaryotes) core proteins that have diverse functions, including site-specific methylation of rRNA and processing rRNA.",box C/D RNP complex,cellular_component
89352,GO:0170050,A ribonucleoprotein complex containing a box C/D type snoRNA and three (Archaea) or four (Eukaryotes) core proteins that is capable of methylation of target RNAs.,box C/D methylation guide RNP complex,cellular_component
89353,GO:0170051,"A ribonucleoprotein complex containing a small CB-specific RNA (scaRNA), with a short sequence motif (GU/UG wobble stem) for CB localization that is capable of methylation of target RNAs.",box C/D methylation guide scaRNP complex,cellular_component
89354,GO:0170052,A ribonucleoprotein complex containing a box C/D type RNA that is involved in pre-rRNA cleavage.,box C/D pre-rRNA cleavage RNP complex,cellular_component
89355,GO:0170053,Binds to and increases the activity of a nuclease.,nuclease activator activity,molecular_function
89356,GO:0170054,Binds to and increases the activity of a ribonuclease.,ribonuclease activator activity,molecular_function
89357,GO:0170055,Enables the transfer of a lipid from one side of a membrane to the other.,lipid transmembrane transporter activity,molecular_function
89358,GO:0170056,Catalysis of the reaction: cholesterol + H+ + NAD(P)H + O2 = 7-dehydrocholesterol + 2 H2O + NAD(P)+.,cholesterol 7-desaturase [NAD(P)H] activity,molecular_function
89359,GO:0170057,"Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+.",RNA ligase (GTP) activity,molecular_function
89360,GO:0170060,A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage).,microtubule destabilizing activity,molecular_function
89361,GO:0170061,Directly binding to and delivering nickel ions to a target protein.,nickel chaperone activity,molecular_function
89362,GO:0170062,"The accumulation and maintenance in cells or tissues of a nutrient, a substance that is used by an organism to survive, to grow, and to reproduce; such as proteins, vitamins, and minerals. Nutrient reserves can be accumulated for mobilization and utilization when needed.",nutrient storage,biological_process
89363,GO:0170063,The directed movement of a solute from the lysosomal lumen across the lysosomal membrane and into the cytosol.,transmembrane transport from lysosomal lumen to cytosol,biological_process
89364,GO:0170064,"The process by which lysosomes undergo budding and fission to maintain their steady-state number, shape, size, composition and function, and to accomplish regeneration.",lysosome fission,biological_process
89365,GO:0170066,"Any process that stops, prevents, or reduces the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.",negative regulation of polyamine biosynthetic process,biological_process
89366,GO:0170068,Catalyzes the covalent addition of a geranylgeranyl group to a mono-farnesylated substrate via a thioether linkage to a cysteine residue located within a conserved C-terminal tandem cysteine motif (CCAIM or CCIIM) that is used in substrate recognition. Known substrates include mono-farnesylated Golgi SNARE proteins.,geranylgeranyltransferase type III activity,molecular_function
89367,GO:0170069,"A protein-containing complex that catalyzes the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a mono-farnsylated substrate. In humans, the complex is comprised of a prenyltransferase alpha subunit, PTAR1 and beta subunit, RabGGTB, while in budding yeast the prenyltransferase complex contains Ecm9p, the alpha subunit and Bet2p, the beta subunit.",geranylgeranyltransferase-III complex,cellular_component
89368,GO:0170070,"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription occurring in the mitochondrion.",negative regulation of mitochondrial transcription,biological_process
89369,GO:0170071,"A complex involved in membrane fission during protein exchange in endo-lysosomal compartments. CROP joins members of two protein families: the peripheral subunits of retromer, a coat forming endosomal transport carriers, and membrane inserting PROPPINs.",CROP complex,cellular_component
89370,GO:0170074,"A quality control pathway that degrades peroxisomal matrix protein receptors when the recycling machinery is blocked. When recycling to the cytosol fails, cargo-free receptors accumulate at the peroxisomal membrane, where they are polyubiquitinated and subsequently degraded by the ubiquitin-proteasome system (UPS).",RADAR pathway,biological_process
89371,GO:0170075,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, no-go decay.","negative regluation of nuclear-transribed mRNA catabolic process, no-go decay",biological_process
89372,GO:0180000,"Binds to and stops, prevents or reduces the activity of a histone methyltransferase.",histone methyltransferase inhibitor activity,molecular_function
89373,GO:0180001,Binding to a cyclic di-AMP nucleotide.,cyclic-di-AMP binding,molecular_function
89374,GO:0180002,The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.,renal zinc excretion,biological_process
89375,GO:0180003,Catalysis of the reaction: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) = S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out).,S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity,molecular_function
89376,GO:0180004,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity,molecular_function
89377,GO:0180005,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity,molecular_function
89378,GO:0180006,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity,molecular_function
89379,GO:0180007,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity,molecular_function
89380,GO:0180008,Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate.,RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity,molecular_function
89381,GO:0180009,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: basic L-amino acid(in) + neutral L-amino acid(out) = basic L-amino acid(in) + neutral L-amino acid(out).,broad specificity neutral L-amino acid:basic L-amino acid antiporter activity,molecular_function
89382,GO:0180010,Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage and addition of a poly(A) tail.,"co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway",biological_process
89383,GO:0180011,"Any process by which dormant, translationally inactive mRNAs become activated, or mRNAs become stabilized, via the elongation of their poly(A) tails in the cytosol.",cytosolic mRNA polyadenylation,biological_process
89384,GO:0180012,Any process involved in transcription termination-coupled 3' processing of RNA polymerase II RNA transcripts by 3' end cleavage and addition of a poly(A) tail.,"co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway",biological_process
89385,GO:0180013,"Catalysis of the movement of a lysophosphatidylserine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.",lysophosphatidylserine flippase activity,molecular_function
89386,GO:0180014,"The binding activity of a protein that brings together another protein and a tRNA, permitting those molecules to function in a coordinated way.",protein-tRNA adaptor activity,molecular_function
89387,GO:0180015,"The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol.",nucleoside import across plasma membrane,biological_process
89388,GO:0180016,Binds to and modulates the activity of a SUMO ligase.,SUMO ligase regulator activity,molecular_function
89389,GO:0180017,Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys11 residue of ubiquitin.,K11-linked deubiquitinase activity,molecular_function
89390,GO:0180018,"The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.",cytoplasmic polyadenylation-dependent RNA catabolic process,biological_process
89391,GO:0180019,"A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans, budding and fission yeast, it consists of KNL1/ZWINT, Spc105p/Kre28p and Spc7/Sos1, members of the Panther PTHR28260 and PTHR37329 families, respectively.",Knl1/Spc105 complex,cellular_component
89392,GO:0180020,The activity of bending or deforming a membrane. This activity can occur by multiple mechanisms including the insertion amphipathic domains into one or both leaflets.,membrane bending activity,molecular_function
89393,GO:0180021,Catalysis of the reaction: S-adenosyl-L-methionine + U6 snRNA = S-adenosyl-L-homocysteine + U6 containing a 3'-terminal 2'-O-methylnucleotide + H+.,U6 snRNA 2'-O-ribose methyltransferase activity,molecular_function
89394,GO:0180022,"A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.",RQC-trigger complex,cellular_component
89395,GO:0180023,"The aggregation, arrangement and bonding together of a set of components to form a cytosolic large ribosomal subunit.",cytosolic large ribosomal subunit assembly,biological_process
89396,GO:0180024,"An activity in which a protein, or group of proteins, acts to restrict the size of a fenestration in a membrane or membrane system (i.e. restrict the diameter of a hole in a membrane). An example of this is the molecular function is performed by ESCRT-III proteins at the nuclear envelope of fission yeast during anaphase B.",membrane grommet activity,molecular_function
89397,GO:0180025,"The aggregation, arrangement and bonding together of a set of components to form a cytosolic small ribosomal subunit.",cytosolic small ribosomal subunit assembly,biological_process
89398,GO:0180026,"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial small ribosomal subunit.",mitochondrial small ribosomal subunit assembly,biological_process
89399,GO:0180027,A protein quality control pathway that removes ubiquitinated proteins from the nuclear inner membrane before transferring them to the proteasome for degradation.,inner nuclear membrane-associated protein degradation pathway,biological_process
89400,GO:0180028,A region of the nuclear envelope to which a spindle pole body (SPB) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.,mitotic spindle pole body attachment site,cellular_component
89401,GO:0180029,"The directed movement of phosphate ions (Pi) from inside of a cell, across the plasma membrane and into the extracellular region.",phosphate ion export across plasma membrane,biological_process
89402,GO:0180030,Catalysis of the reaction: inositol phosphate + ATP = inositol phosphate + ADP.,inositol phosphate kinase activity,molecular_function
89403,GO:0180031,"The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snoRNA. The snoRNA capping includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed snoRNAs are also TMG capped.","snoRNA 2,2,7-trimethylguanosine (TMG) capping",biological_process
89404,GO:0180032,Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 5) + H2O = histone H4 L-lysine (position 5) + acetate. This reaction represents the removal of an acetyl group from lysine at position 5 of the histone H4 protein.,"histone H4K5 deacetylase activity, hydrolytic mechanism",molecular_function
89405,GO:0180033,Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 8) + H2O = histone H4 L-lysine (position 8) + acetate. This reaction represents the removal of an acetyl group from lysine at position 8 of the histone H4 protein.,"histone H4K8 deacetylase activity, hydrolytic mechanism",molecular_function
89406,GO:0180034,Any process involved in transcription termination-coupled 3' processing of RNA polymerase II lncRNA transcripts by the 3' end cleavage and addition of a poly(A) tail.,"co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway",biological_process
89407,GO:0180035,Any process involved in the conversion of one or more primary lncRNA transcripts into one or more mature lncRNA molecules.,lncRNA processing,biological_process
89408,GO:0180036,A process that identifies and degrades defective or aberrant lncRNAs within the nucleus.,nuclear lncRNA surveillance,biological_process
89409,GO:0180037,"A cytoplasmic tRNA surveillance pathway that targets mature hypomodified tRNAs, catalyzed by 5'-3' exonucleases Xrn1 (S. cerevisiae/human) and Rat1 (S. cerevisiae) XRN2 human, and regulated by adenosine 3',5' bisphosphate (pAp).",rapid tRNA decay,biological_process
89410,GO:0180038,A protein complex consisting of cyclin L and cyclin-dependent kinase 11 (CDK11). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.,cyclin L-CDK11 complex,cellular_component
89411,GO:0180039,"Any process that modulates the frequency, rate or extent of a pheromone response MAPK cascade.",regulation of pheromone response MAPK cascade,biological_process
89412,GO:0180040,"Any process that stops, prevents or reduces the frequency, rate or extent of a pheromone response MAPK cascade.",negative regulation of pheromone response MAPK cascade,biological_process
89413,GO:0180041,"Catalysis of the reaction: a 2-acyl-6-alpha-D-glucosaminyl-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H+.","dol-P-Man:GlcN-acyl-PI alpha-1,4-mannosyltransferase activity",molecular_function
89414,GO:0180042,The directed movement of polyphosphate into the vacuole across the vacuolar membrane.,polyphosphate import into vacuole,biological_process
89415,GO:0180043,"Binding to and responding, e.g. by conformational change, to changes in the cellular level of an inositol pyrophosphate.",inositol pyrophosphate sensor activity,molecular_function
89416,GO:0180044,Enables the facilitated diffusion of borate (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.,borate channel activity,molecular_function
89417,GO:0180045,The selective autophagy process in which a functional mitochondrion is degraded by macroautophagy to provide metabolic precursors during nutrient deprivation or to remove mitochondria in excess of metabolic needs.,type 1 mitophagy,biological_process
89418,GO:0180046,Any process leading to the post-translational modification of a protein with a GPI anchor to achieve full functional capacity of the protein.,GPI anchored protein biosynthesis,biological_process
89419,GO:0180047,The chemical reactions and pathways resulting in the formation of dolichol phosphate mannose.,dolichol phosphate mannose biosynthetic process,biological_process
89420,GO:0180048,The chemical reactions and pathways resulting in the formation of phosphatidylinositol 4-phosphate.,phosphatidylinositol 4-phosphate biosynthetic process,biological_process
89421,GO:0180049,"A protein complex capable of translation activator activity, and is involved in the activation of cox1 mRNA for translation. In fission yeast this complex consists of a scaffold (Sls1), a helicase (Mrh5), and PPR repeat proteins Prr4 and Mtf2.",Mrh5C translation activator complex,cellular_component
89422,GO:0180050,"The binding activity of a molecule that brings together a protein or protein complex and a mitochondrial outer membrane lipid or membrane-associated protein, in order to maintain the localization of the protein, or protein complex at a specific mitochondrial outer membrane location.",protein-mitochondrial outer membrane tethering activity,molecular_function
89423,GO:0180051,"A molecular function required for translation of a mRNA into a protein functioning as part of initiation, elongation or termination of translation.",translation factor activity,molecular_function
89424,GO:0180052,A ribonucleoprotein complex comprising the mRNA bound fully assembled 55S mitoribosome with the tRNA-met positioned in the P-site of the mitochondrial small subunit to recognize the mRNA start codon.,mitochondrial translation initiation complex,cellular_component
89425,GO:0180053,"A ribonucleoprotein complex comprising of the 28S small mitoribosomal subunit (mt-SSU) and mitochondrial initiation factors (e.g. mtIF3 and mtIF2-GTP) and the initiator tRNA-Met and an mRNA binding. The early steps of translation initiation, including the association of the 28S mitochondrial small subunit (mt-SSU) with initiation factors (mtIF3 and mtIF2), prevention of premature large subunit (39S) joining occur during the assembly of the mitochondrial pre-initiation complex (mtPIC).",mitochondrial translation preinitiation complex,cellular_component
89426,GO:0180054,"A motor activity that generates movement of a ribosome one codon forward along the mRNA, driven by GTP hydrolysis.",ribosome translocase activity,molecular_function
89427,GO:0180055,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of some metal ion.",response to metal ion starvation,biological_process
89428,GO:0180056,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + 2-oxogluarate(in) = citrate(in) + 2-oxogluarat(out).,citrate:2-oxoglutarate antiporter activity,molecular_function
89429,GO:0180057,A N-linked protein glycosylation process in which the preassembled dolichol-linked oligosaccharide precursor is transfered co-translationally to an asparagine residue within the motif Asn-X-Ser/Thr of the target protein. This is mediated by the OSTB complex.,protein post-translational transfer of dolichol-linked oligosaccharide,biological_process
89430,GO:0180058,A N-linked protein glycosylation process in which the preassembled dolichol-linked oligosaccharide precursor is transfered post-translationally to an asparagine residue within the motif Asn-X-Ser/Thr of the target protein. This is mediated by the OSTA complex.,protein co-translational transfer of dolichol-linked oligosaccharide,biological_process
89431,GO:0180059,"A glycoprotein biosynthetic process starting with the covalent linkage of a glucose via a beta-glycosidic bond to the oxygen atom of a serine, threonine or tyrosine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation via glucose,biological_process
89432,GO:0180060,"A process in which iron siderophores (low-molecular-weight, high-affinity iron-chelating compounds) are exported to scavenge iron and the iron-loaded siderophores imported back into the cell by transmembrane transport or endocytosis.",siderophore-dependent iron import pathway,biological_process
89433,GO:0180061,"The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from inside of a cell, across the plasma membrane and into the extracellular region.",native siderophore export across plasma membrane,biological_process
89434,GO:0180062,"A glycoprotein biosynthetic process starting with the covalent linkage of galactose via a beta-glycosidic bond to the oxygen atom of the hydroxyl group of a hydroxyproline, a hydroxylysine, a serine or a threonine in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan. Hydroxylysine modification occurs in the endoplasmic reticulum and is predominantly found in collagen. Hydroxyproline modification occurs...",protein O-linked glycosylation via galactose,biological_process
89435,GO:0180063,"A glycoprotein biosynthetic process starting with the covalent linkage of an arabinose via a beta-glycosidic bond to the oxygen atom of the hydroxyl group of a hydroxyproline in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation via arabinose,biological_process
89436,GO:0180064,"A glycoprotein biosynthetic process starting with the covalent linkage of a xylose via a beta-glycosidic bond to the oxygen atom of a serine or a threonine side chain in a protein, which can be further elongated with the sequential addition of sugar units resulting in the formation of a protein O-linked glycan.",protein O-linked glycosylation via xylose,biological_process
89437,GO:0180065,Binding to a mitochondrial small ribosomal subunit.,mitochondrial small ribosomal subunit binding,molecular_function
89438,GO:0180066,A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation by the mitochondrial RNA polymerase.,mitochondrial RNA polymerase general transcription initiation factor activity,molecular_function
89439,GO:0180067,"The chemical reactions and pathways resulting in the formation of terreate, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities.",terreate biosynthetic process,biological_process
89440,GO:0180068,"Any process that  that stops, prevents, or reduces the frequency, rate or extent of carbohydrate utilization.",negative regulation of carbohydrate utilization,biological_process
89441,GO:0180069,"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of terreate.",positive regulation of terreate biosynthetic process,biological_process
89442,GO:1900000,"Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.",regulation of anthocyanin catabolic process,biological_process
89443,GO:1900001,"Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.",negative regulation of anthocyanin catabolic process,biological_process
89444,GO:1900002,"Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.",positive regulation of anthocyanin catabolic process,biological_process
89445,GO:1900003,"Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.",regulation of serine-type endopeptidase activity,biological_process
89446,GO:1900004,"Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.",negative regulation of serine-type endopeptidase activity,biological_process
89447,GO:1900005,"Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.",positive regulation of serine-type endopeptidase activity,biological_process
89448,GO:1900006,"Any process that activates or increases the frequency, rate or extent of dendrite development.",positive regulation of dendrite development,biological_process
89449,GO:1900011,"Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.",negative regulation of corticotropin-releasing hormone receptor activity,biological_process
89450,GO:1900015,"Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.",regulation of cytokine production involved in inflammatory response,biological_process
89451,GO:1900016,"Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.",negative regulation of cytokine production involved in inflammatory response,biological_process
89452,GO:1900017,"Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.",positive regulation of cytokine production involved in inflammatory response,biological_process
89453,GO:1900019,"Any process that modulates the frequency, rate or extent of protein kinase C activity.",regulation of protein kinase C activity,biological_process
89454,GO:1900020,"Any process that activates or increases the frequency, rate or extent of protein kinase C activity.",positive regulation of protein kinase C activity,biological_process
89455,GO:1900024,"Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.",regulation of substrate adhesion-dependent cell spreading,biological_process
89456,GO:1900025,"Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.",negative regulation of substrate adhesion-dependent cell spreading,biological_process
89457,GO:1900026,"Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.",positive regulation of substrate adhesion-dependent cell spreading,biological_process
89458,GO:1900027,"Any process that modulates the frequency, rate or extent of ruffle assembly.",regulation of ruffle assembly,biological_process
89459,GO:1900028,"Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.",negative regulation of ruffle assembly,biological_process
89460,GO:1900029,"Any process that activates or increases the frequency, rate or extent of ruffle assembly.",positive regulation of ruffle assembly,biological_process
89461,GO:1900030,"Any process that modulates the frequency, rate or extent of pectin biosynthetic process.",regulation of pectin biosynthetic process,biological_process
89462,GO:1900032,"Any process that modulates the frequency, rate or extent of trichome patterning.",regulation of trichome patterning,biological_process
89463,GO:1900033,"Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning.",negative regulation of trichome patterning,biological_process
89464,GO:1900034,"Any process that modulates the frequency, rate or extent of cellular response to heat.",regulation of cellular response to heat,biological_process
89465,GO:1900035,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.",negative regulation of cellular response to heat,biological_process
89466,GO:1900036,"Any process that activates or increases the frequency, rate or extent of cellular response to heat.",positive regulation of cellular response to heat,biological_process
89467,GO:1900037,"Any process that modulates the frequency, rate or extent of cellular response to hypoxia.",regulation of cellular response to hypoxia,biological_process
89468,GO:1900038,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.",negative regulation of cellular response to hypoxia,biological_process
89469,GO:1900039,"Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia.",positive regulation of cellular response to hypoxia,biological_process
89470,GO:1900044,"Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.",regulation of protein K63-linked ubiquitination,biological_process
89471,GO:1900045,"Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination.",negative regulation of protein K63-linked ubiquitination,biological_process
89472,GO:1900046,"Any process that modulates the frequency, rate or extent of hemostasis.",regulation of hemostasis,biological_process
89473,GO:1900047,"Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.",negative regulation of hemostasis,biological_process
89474,GO:1900048,"Any process that activates or increases the frequency, rate or extent of hemostasis.",positive regulation of hemostasis,biological_process
89475,GO:1900052,"Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.",regulation of retinoic acid biosynthetic process,biological_process
89476,GO:1900053,"Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process.",negative regulation of retinoic acid biosynthetic process,biological_process
89477,GO:1900054,"Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.",positive regulation of retinoic acid biosynthetic process,biological_process
89478,GO:1900055,"Any process that modulates the frequency, rate or extent of leaf senescence.",regulation of leaf senescence,biological_process
89479,GO:1900056,"Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.",negative regulation of leaf senescence,biological_process
89480,GO:1900057,"Any process that activates or increases the frequency, rate or extent of leaf senescence.",positive regulation of leaf senescence,biological_process
89481,GO:1900058,"Any process that modulates the frequency, rate or extent of sulfate assimilation.",regulation of sulfate assimilation,biological_process
89482,GO:1900059,"Any process that activates or increases the frequency, rate or extent of sulfate assimilation.",positive regulation of sulfate assimilation,biological_process
89483,GO:1900060,"Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.",negative regulation of ceramide biosynthetic process,biological_process
89484,GO:1900063,"Any process that modulates the frequency, rate or extent of peroxisome organization.",regulation of peroxisome organization,biological_process
89485,GO:1900064,"Any process that activates or increases the frequency, rate or extent of peroxisome organization.",positive regulation of peroxisome organization,biological_process
89486,GO:1900065,"Any process that modulates the frequency, rate or extent of ethanol catabolic process.",regulation of ethanol catabolic process,biological_process
89487,GO:1900066,"Any process that activates or increases the frequency, rate or extent of ethanol catabolic process.",positive regulation of ethanol catabolic process,biological_process
89488,GO:1900067,"Any process that modulates the frequency, rate or extent of cellular response to alkalinity.",regulation of cellular response to alkaline pH,biological_process
89489,GO:1900068,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.",negative regulation of cellular response to alkaline pH,biological_process
89490,GO:1900069,"Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.",regulation of cellular hyperosmotic salinity response,biological_process
89491,GO:1900070,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.",negative regulation of cellular hyperosmotic salinity response,biological_process
89492,GO:1900071,"Any process that modulates the frequency, rate or extent of sulfite transmembrane transport.",regulation of sulfite transmembrane transport,biological_process
89493,GO:1900072,"Any process that activates or increases the frequency, rate or extent of sulfite transmembrane transport.",positive regulation of sulfite transmembrane transport,biological_process
89494,GO:1900073,"Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.",regulation of neuromuscular synaptic transmission,biological_process
89495,GO:1900074,"Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.",negative regulation of neuromuscular synaptic transmission,biological_process
89496,GO:1900075,"Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.",positive regulation of neuromuscular synaptic transmission,biological_process
89497,GO:1900076,"Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.",regulation of cellular response to insulin stimulus,biological_process
89498,GO:1900077,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.",negative regulation of cellular response to insulin stimulus,biological_process
89499,GO:1900078,"Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.",positive regulation of cellular response to insulin stimulus,biological_process
89500,GO:1900079,"Any process that modulates the frequency, rate or extent of arginine biosynthetic process.",regulation of arginine biosynthetic process,biological_process
89501,GO:1900080,"Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process.",positive regulation of arginine biosynthetic process,biological_process
89502,GO:1900081,"Any process that modulates the frequency, rate or extent of arginine catabolic process.",regulation of arginine catabolic process,biological_process
89503,GO:1900082,"Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process.",negative regulation of arginine catabolic process,biological_process
89504,GO:1900084,"Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.",regulation of peptidyl-tyrosine autophosphorylation,biological_process
89505,GO:1900085,"Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.",negative regulation of peptidyl-tyrosine autophosphorylation,biological_process
89506,GO:1900086,"Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.",positive regulation of peptidyl-tyrosine autophosphorylation,biological_process
89507,GO:1900087,Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.,positive regulation of G1/S transition of mitotic cell cycle,biological_process
89508,GO:1900088,"Any process that modulates the frequency, rate or extent of inositol biosynthetic process.",regulation of inositol biosynthetic process,biological_process
89509,GO:1900089,"Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process.",negative regulation of inositol biosynthetic process,biological_process
89510,GO:1900090,"Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process.",positive regulation of inositol biosynthetic process,biological_process
89511,GO:1900091,"Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.",regulation of raffinose biosynthetic process,biological_process
89512,GO:1900092,"Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.",negative regulation of raffinose biosynthetic process,biological_process
89513,GO:1900093,"Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process.",positive regulation of raffinose biosynthetic process,biological_process
89514,GO:1900098,"Any process that modulates the frequency, rate or extent of plasma cell differentiation.",regulation of plasma cell differentiation,biological_process
89515,GO:1900099,"Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.",negative regulation of plasma cell differentiation,biological_process
89516,GO:1900100,"Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.",positive regulation of plasma cell differentiation,biological_process
89517,GO:1900101,"Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.",regulation of endoplasmic reticulum unfolded protein response,biological_process
89518,GO:1900102,"Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.",negative regulation of endoplasmic reticulum unfolded protein response,biological_process
89519,GO:1900103,"Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.",positive regulation of endoplasmic reticulum unfolded protein response,biological_process
89520,GO:1900104,"Any process that modulates the frequency, rate or extent of hyaluranon cable assembly.",regulation of hyaluranon cable assembly,biological_process
89521,GO:1900105,"Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly.",negative regulation of hyaluranon cable assembly,biological_process
89522,GO:1900106,"Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.",positive regulation of hyaluranon cable assembly,biological_process
89523,GO:1900107,"Any process that modulates the frequency, rate or extent of nodal signaling pathway.",regulation of nodal signaling pathway,biological_process
89524,GO:1900108,"Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.",negative regulation of nodal signaling pathway,biological_process
89525,GO:1900115,Any regulation of signal transduction that takes place in the extracellular region.,extracellular regulation of signal transduction,biological_process
89526,GO:1900116,Any negative regulation of signal transduction that takes place in extracellular region.,extracellular negative regulation of signal transduction,biological_process
89527,GO:1900117,"Any process that modulates the frequency, rate or extent of execution phase of apoptosis.",regulation of execution phase of apoptosis,biological_process
89528,GO:1900118,"Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.",negative regulation of execution phase of apoptosis,biological_process
89529,GO:1900119,"Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.",positive regulation of execution phase of apoptosis,biological_process
89530,GO:1900120,"Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.",regulation of receptor binding,biological_process
89531,GO:1900121,"Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.",negative regulation of receptor binding,biological_process
89532,GO:1900123,"Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.",regulation of nodal receptor complex assembly,biological_process
89533,GO:1900124,"Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly.",negative regulation of nodal receptor complex assembly,biological_process
89534,GO:1900125,"Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.",regulation of hyaluronan biosynthetic process,biological_process
89535,GO:1900126,"Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.",negative regulation of hyaluronan biosynthetic process,biological_process
89536,GO:1900127,"Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.",positive regulation of hyaluronan biosynthetic process,biological_process
89537,GO:1900131,"Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.",negative regulation of lipid binding,biological_process
89538,GO:1900133,"Any process that modulates the frequency, rate or extent of renin secretion into blood stream.",regulation of renin secretion into blood stream,biological_process
89539,GO:1900134,"Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.",negative regulation of renin secretion into blood stream,biological_process
89540,GO:1900135,"Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.",positive regulation of renin secretion into blood stream,biological_process
89541,GO:1900136,"Any process that modulates the frequency, rate or extent of chemokine activity.",regulation of chemokine activity,biological_process
89542,GO:1900137,"Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.",negative regulation of chemokine activity,biological_process
89543,GO:1900139,"Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.",negative regulation of arachidonate secretion,biological_process
89544,GO:1900140,"Any process that modulates the frequency, rate or extent of seedling development.",regulation of seedling development,biological_process
89545,GO:1900141,"Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.",regulation of oligodendrocyte apoptotic process,biological_process
89546,GO:1900142,"Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.",negative regulation of oligodendrocyte apoptotic process,biological_process
89547,GO:1900143,"Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.",positive regulation of oligodendrocyte apoptotic process,biological_process
89548,GO:1900144,"Any process that activates or increases the frequency, rate or extent of BMP secretion.",positive regulation of BMP secretion,biological_process
89549,GO:1900147,"Any process that modulates the frequency, rate or extent of Schwann cell migration.",regulation of Schwann cell migration,biological_process
89550,GO:1900148,"Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.",negative regulation of Schwann cell migration,biological_process
89551,GO:1900149,"Any process that activates or increases the frequency, rate or extent of Schwann cell migration.",positive regulation of Schwann cell migration,biological_process
89552,GO:1900150,"Any process that modulates the frequency, rate or extent of defense response to fungus.",regulation of defense response to fungus,biological_process
89553,GO:1900151,"Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.","regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",biological_process
89554,GO:1900152,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.","negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",biological_process
89555,GO:1900153,"Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.","positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",biological_process
89556,GO:1900154,"Any process that modulates the frequency, rate or extent of bone trabecula formation.",regulation of bone trabecula formation,biological_process
89557,GO:1900155,"Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.",negative regulation of bone trabecula formation,biological_process
89558,GO:1900156,"Any process that activates or increases the frequency, rate or extent of bone trabecula formation.",positive regulation of bone trabecula formation,biological_process
89559,GO:1900158,"Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.",negative regulation of bone mineralization involved in bone maturation,biological_process
89560,GO:1900159,"Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.",positive regulation of bone mineralization involved in bone maturation,biological_process
89561,GO:1900160,"A process in which plastidial DNA and associated proteins organize into a compact, orderly structure.",plastid chromosome packaging,biological_process
89562,GO:1900163,"Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.",positive regulation of phospholipid scramblase activity,biological_process
89563,GO:1900166,"Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production.",regulation of glial cell-derived neurotrophic factor production,biological_process
89564,GO:1900167,"Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.",negative regulation of glial cell-derived neurotrophic factor production,biological_process
89565,GO:1900168,"Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production.",positive regulation of glial cell-derived neurotrophic factor production,biological_process
89566,GO:1900177,"Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.",regulation of aflatoxin biosynthetic process,biological_process
89567,GO:1900178,"Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.",negative regulation of aflatoxin biosynthetic process,biological_process
89568,GO:1900179,"Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.",positive regulation of aflatoxin biosynthetic process,biological_process
89569,GO:1900180,"Any process that modulates the frequency, rate or extent of protein localization to nucleus.",regulation of protein localization to nucleus,biological_process
89570,GO:1900181,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.",negative regulation of protein localization to nucleus,biological_process
89571,GO:1900182,"Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.",positive regulation of protein localization to nucleus,biological_process
89572,GO:1900183,"Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process.",regulation of xanthone-containing compound biosynthetic process,biological_process
89573,GO:1900184,"Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process.",negative regulation of xanthone-containing compound biosynthetic process,biological_process
89574,GO:1900185,"Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process.",positive regulation of xanthone-containing compound biosynthetic process,biological_process
89575,GO:1900186,"Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.",negative regulation of clathrin-dependent endocytosis,biological_process
89576,GO:1900188,"Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.",negative regulation of cell adhesion involved in single-species biofilm formation,biological_process
89577,GO:1900189,"Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.",positive regulation of cell adhesion involved in single-species biofilm formation,biological_process
89578,GO:1900190,"Any process that modulates the frequency, rate or extent of single-species biofilm formation.",regulation of single-species biofilm formation,biological_process
89579,GO:1900191,"Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.",negative regulation of single-species biofilm formation,biological_process
89580,GO:1900192,"Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.",positive regulation of single-species biofilm formation,biological_process
89581,GO:1900193,"Any process that modulates the frequency, rate or extent of oocyte maturation.",regulation of oocyte maturation,biological_process
89582,GO:1900194,"Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.",negative regulation of oocyte maturation,biological_process
89583,GO:1900195,"Any process that activates or increases the frequency, rate or extent of oocyte maturation.",positive regulation of oocyte maturation,biological_process
89584,GO:1900196,"Any process that modulates the frequency, rate or extent of penicillin biosynthetic process.",regulation of penicillin biosynthetic process,biological_process
89585,GO:1900197,"Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.",negative regulation of penicillin biosynthetic process,biological_process
89586,GO:1900198,"Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process.",positive regulation of penicillin biosynthetic process,biological_process
89587,GO:1900199,"Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.",positive regulation of protein export from nucleus during meiotic anaphase II,biological_process
89588,GO:1900200,Any mesenchymal cell apoptotic process that is involved in metanephros development.,mesenchymal cell apoptotic process involved in metanephros development,biological_process
89589,GO:1900206,"Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.",regulation of pronephric nephron tubule development,biological_process
89590,GO:1900207,"Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.",negative regulation of pronephric nephron tubule development,biological_process
89591,GO:1900208,"Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.",regulation of cardiolipin metabolic process,biological_process
89592,GO:1900209,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.",negative regulation of cardiolipin metabolic process,biological_process
89593,GO:1900210,"Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.",positive regulation of cardiolipin metabolic process,biological_process
89594,GO:1900212,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.",negative regulation of mesenchymal cell apoptotic process involved in metanephros development,biological_process
89595,GO:1900221,"Any process that modulates the frequency, rate or extent of amyloid-beta clearance.",regulation of amyloid-beta clearance,biological_process
89596,GO:1900222,"Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance.",negative regulation of amyloid-beta clearance,biological_process
89597,GO:1900223,"Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance.",positive regulation of amyloid-beta clearance,biological_process
89598,GO:1900225,"Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.",regulation of NLRP3 inflammasome complex assembly,biological_process
89599,GO:1900226,"Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.",negative regulation of NLRP3 inflammasome complex assembly,biological_process
89600,GO:1900227,"Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.",positive regulation of NLRP3 inflammasome complex assembly,biological_process
89601,GO:1900228,"Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.",regulation of single-species biofilm formation in or on host organism,biological_process
89602,GO:1900229,"Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism.",negative regulation of single-species biofilm formation in or on host organism,biological_process
89603,GO:1900230,"Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.",positive regulation of single-species biofilm formation in or on host organism,biological_process
89604,GO:1900231,"Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.",regulation of single-species biofilm formation on inanimate substrate,biological_process
89605,GO:1900232,"Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.",negative regulation of single-species biofilm formation on inanimate substrate,biological_process
89606,GO:1900233,"Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.",positive regulation of single-species biofilm formation on inanimate substrate,biological_process
89607,GO:1900234,"Any process that modulates the frequency, rate or extent of Kit signaling pathway.",regulation of Kit signaling pathway,biological_process
89608,GO:1900235,"Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.",negative regulation of Kit signaling pathway,biological_process
89609,GO:1900236,"Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.",positive regulation of Kit signaling pathway,biological_process
89610,GO:1900238,"Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.",regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway,biological_process
89611,GO:1900239,"Any process that modulates the frequency, rate or extent of phenotypic switching.",regulation of phenotypic switching,biological_process
89612,GO:1900240,"Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.",negative regulation of phenotypic switching,biological_process
89613,GO:1900241,"Any process that activates or increases the frequency, rate or extent of phenotypic switching.",positive regulation of phenotypic switching,biological_process
89614,GO:1900242,"Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.",regulation of synaptic vesicle endocytosis,biological_process
89615,GO:1900243,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.",negative regulation of synaptic vesicle endocytosis,biological_process
89616,GO:1900244,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.",positive regulation of synaptic vesicle endocytosis,biological_process
89617,GO:1900245,"Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.",positive regulation of MDA-5 signaling pathway,biological_process
89618,GO:1900246,"Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.",positive regulation of RIG-I signaling pathway,biological_process
89619,GO:1900247,"Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.",regulation of cytoplasmic translational elongation,biological_process
89620,GO:1900248,"Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.",negative regulation of cytoplasmic translational elongation,biological_process
89621,GO:1900249,"Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.",positive regulation of cytoplasmic translational elongation,biological_process
89622,GO:1900260,"Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.",negative regulation of RNA-dependent RNA polymerase activity,biological_process
89623,GO:1900264,"Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.",positive regulation of DNA-directed DNA polymerase activity,biological_process
89624,GO:1900268,"Any process that modulates the frequency, rate or extent of reverse transcription.",regulation of reverse transcription,biological_process
89625,GO:1900269,"Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.",negative regulation of reverse transcription,biological_process
89626,GO:1900270,"Any process that activates or increases the frequency, rate or extent of reverse transcription.",positive regulation of reverse transcription,biological_process
89627,GO:1900271,"Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.",regulation of long-term synaptic potentiation,biological_process
89628,GO:1900272,"Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.",negative regulation of long-term synaptic potentiation,biological_process
89629,GO:1900273,"Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.",positive regulation of long-term synaptic potentiation,biological_process
89630,GO:1900279,"Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.","regulation of CD4-positive, alpha-beta T cell costimulation",biological_process
89631,GO:1900280,"Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.","negative regulation of CD4-positive, alpha-beta T cell costimulation",biological_process
89632,GO:1900281,"Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.","positive regulation of CD4-positive, alpha-beta T cell costimulation",biological_process
89633,GO:1900282,"Any process that modulates the frequency, rate or extent of cellobiose catabolic process.",regulation of cellobiose catabolic process,biological_process
89634,GO:1900283,"Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.",negative regulation of cellobiose catabolic process,biological_process
89635,GO:1900284,"Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.",positive regulation of cellobiose catabolic process,biological_process
89636,GO:1900285,"Any process that modulates the frequency, rate or extent of cellotriose transport.",regulation of cellotriose transport,biological_process
89637,GO:1900286,"Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.",negative regulation of cellotriose transport,biological_process
89638,GO:1900287,"Any process that activates or increases the frequency, rate or extent of cellotriose transport.",positive regulation of cellotriose transport,biological_process
89639,GO:1900288,"Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.",regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process,biological_process
89640,GO:1900289,"Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.",negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process,biological_process
89641,GO:1900290,"Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.",positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process,biological_process
89642,GO:1900291,"Any process that modulates the frequency, rate or extent of galactotriose transport.",regulation of galactotriose transport,biological_process
89643,GO:1900292,"Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport.",negative regulation of galactotriose transport,biological_process
89644,GO:1900293,"Any process that activates or increases the frequency, rate or extent of galactotriose transport.",positive regulation of galactotriose transport,biological_process
89645,GO:1900294,"Any process that modulates the frequency, rate or extent of heptasaccharide transport.",regulation of heptasaccharide transport,biological_process
89646,GO:1900295,"Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.",negative regulation of heptasaccharide transport,biological_process
89647,GO:1900296,"Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.",positive regulation of heptasaccharide transport,biological_process
89648,GO:1900297,"Any process that modulates the frequency, rate or extent of hexasaccharide transport.",regulation of hexasaccharide transport,biological_process
89649,GO:1900298,"Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.",negative regulation of hexasaccharide transport,biological_process
89650,GO:1900299,"Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.",positive regulation of hexasaccharide transport,biological_process
89651,GO:1900303,"Any process that modulates the frequency, rate or extent of laminaritriose transport.",regulation of laminaritriose transport,biological_process
89652,GO:1900304,"Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport.",negative regulation of laminaritriose transport,biological_process
89653,GO:1900305,"Any process that activates or increases the frequency, rate or extent of laminaritriose transport.",positive regulation of laminaritriose transport,biological_process
89654,GO:1900306,"Any process that modulates the frequency, rate or extent of maltoheptaose transport.",regulation of maltoheptaose transport,biological_process
89655,GO:1900307,"Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport.",negative regulation of maltoheptaose transport,biological_process
89656,GO:1900308,"Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.",positive regulation of maltoheptaose transport,biological_process
89657,GO:1900312,"Any process that modulates the frequency, rate or extent of maltohexaose transport.",regulation of maltohexaose transport,biological_process
89658,GO:1900313,"Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.",negative regulation of maltohexaose transport,biological_process
89659,GO:1900314,"Any process that activates or increases the frequency, rate or extent of maltohexaose transport.",positive regulation of maltohexaose transport,biological_process
89660,GO:1900315,"Any process that modulates the frequency, rate or extent of maltopentaose transport.",regulation of maltopentaose transport,biological_process
89661,GO:1900316,"Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport.",negative regulation of maltopentaose transport,biological_process
89662,GO:1900317,"Any process that activates or increases the frequency, rate or extent of maltopentaose transport.",positive regulation of maltopentaose transport,biological_process
89663,GO:1900321,"Any process that modulates the frequency, rate or extent of maltotetraose transport.",regulation of maltotetraose transport,biological_process
89664,GO:1900322,"Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.",negative regulation of maltotetraose transport,biological_process
89665,GO:1900323,"Any process that activates or increases the frequency, rate or extent of maltotetraose transport.",positive regulation of maltotetraose transport,biological_process
89666,GO:1900324,"Any process that modulates the frequency, rate or extent of maltotriulose transport.",regulation of maltotriulose transport,biological_process
89667,GO:1900325,"Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.",negative regulation of maltotriulose transport,biological_process
89668,GO:1900326,"Any process that activates or increases the frequency, rate or extent of maltotriulose transport.",positive regulation of maltotriulose transport,biological_process
89669,GO:1900327,"Any process that modulates the frequency, rate or extent of mannotriose transport.",regulation of mannotriose transport,biological_process
89670,GO:1900328,"Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.",negative regulation of mannotriose transport,biological_process
89671,GO:1900329,"Any process that activates or increases the frequency, rate or extent of mannotriose transport.",positive regulation of mannotriose transport,biological_process
89672,GO:1900351,"Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.",regulation of methanofuran biosynthetic process,biological_process
89673,GO:1900352,"Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process.",negative regulation of methanofuran biosynthetic process,biological_process
89674,GO:1900353,"Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.",positive regulation of methanofuran biosynthetic process,biological_process
89675,GO:1900357,"Any process that modulates the frequency, rate or extent of nigerotriose transport.",regulation of nigerotriose transport,biological_process
89676,GO:1900358,"Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.",negative regulation of nigerotriose transport,biological_process
89677,GO:1900359,"Any process that activates or increases the frequency, rate or extent of nigerotriose transport.",positive regulation of nigerotriose transport,biological_process
89678,GO:1900360,"Any process that modulates the frequency, rate or extent of pentasaccharide transport.",regulation of pentasaccharide transport,biological_process
89679,GO:1900361,"Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport.",negative regulation of pentasaccharide transport,biological_process
89680,GO:1900362,"Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.",positive regulation of pentasaccharide transport,biological_process
89681,GO:1900366,"Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.",negative regulation of defense response to insect,biological_process
89682,GO:1900367,"Any process that activates or increases the frequency, rate or extent of defense response to insect.",positive regulation of defense response to insect,biological_process
89683,GO:1900368,"Any process that modulates the frequency, rate or extent of post-transcriptional gene silencing by a non-coding RNA.",regulation of post-transcriptional gene silencing by regulatory ncRNA,biological_process
89684,GO:1900369,"Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA.",negative regulation of post-transcriptional gene silencing by regulatory ncRNA,biological_process
89685,GO:1900370,"Any process that activates or increases the frequency, rate or extent of post-transcriptional gene silencing by RNA.",positive regulation of post-transcriptional gene silencing by RNA,biological_process
89686,GO:1900371,"Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.",regulation of purine nucleotide biosynthetic process,biological_process
89687,GO:1900372,"Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.",negative regulation of purine nucleotide biosynthetic process,biological_process
89688,GO:1900373,"Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.",positive regulation of purine nucleotide biosynthetic process,biological_process
89689,GO:1900376,"Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.",regulation of secondary metabolite biosynthetic process,biological_process
89690,GO:1900377,"Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.",negative regulation of secondary metabolite biosynthetic process,biological_process
89691,GO:1900378,"Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.",positive regulation of secondary metabolite biosynthetic process,biological_process
89692,GO:1900379,"Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process.",regulation of asperthecin biosynthetic process,biological_process
89693,GO:1900380,"Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process.",negative regulation of asperthecin biosynthetic process,biological_process
89694,GO:1900381,"Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process.",positive regulation of asperthecin biosynthetic process,biological_process
89695,GO:1900383,"Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse.",regulation of synaptic plasticity by receptor localization to synapse,biological_process
89696,GO:1900384,"Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.",regulation of flavonol biosynthetic process,biological_process
89697,GO:1900385,"Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.",negative regulation of flavonol biosynthetic process,biological_process
89698,GO:1900386,"Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process.",positive regulation of flavonol biosynthetic process,biological_process
89699,GO:1900394,"Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process.",regulation of kojic acid biosynthetic process,biological_process
89700,GO:1900395,"Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process.",negative regulation of kojic acid biosynthetic process,biological_process
89701,GO:1900396,"Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process.",positive regulation of kojic acid biosynthetic process,biological_process
89702,GO:1900397,"Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.",regulation of pyrimidine nucleotide biosynthetic process,biological_process
89703,GO:1900398,"Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.",negative regulation of pyrimidine nucleotide biosynthetic process,biological_process
89704,GO:1900399,"Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.",positive regulation of pyrimidine nucleotide biosynthetic process,biological_process
89705,GO:1900407,"Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.",regulation of cellular response to oxidative stress,biological_process
89706,GO:1900408,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.",negative regulation of cellular response to oxidative stress,biological_process
89707,GO:1900409,"Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.",positive regulation of cellular response to oxidative stress,biological_process
89708,GO:1900419,"Any process that modulates the frequency, rate or extent of alcohol catabolic process within a cell.",regulation of alcohol catabolic process,biological_process
89709,GO:1900420,"Any process that stops, prevents or reduces the frequency, rate or extent of  alcohol catabolic process within a cell.",negative regulation of alcohol catabolic process,biological_process
89710,GO:1900421,"Any process that activates or increases the frequency, rate or extent of alcohol catabolic process within a cell.",positive regulation of alcohol catabolic process,biological_process
89711,GO:1900424,"Any process that modulates the frequency, rate or extent of defense response to bacterium.",regulation of defense response to bacterium,biological_process
89712,GO:1900425,"Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.",negative regulation of defense response to bacterium,biological_process
89713,GO:1900426,"Any process that activates or increases the frequency, rate or extent of defense response to bacterium.",positive regulation of defense response to bacterium,biological_process
89714,GO:1900428,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.",regulation of filamentous growth of a population of unicellular organisms,biological_process
89715,GO:1900429,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.",negative regulation of filamentous growth of a population of unicellular organisms,biological_process
89716,GO:1900430,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms.",positive regulation of filamentous growth of a population of unicellular organisms,biological_process
89717,GO:1900431,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.",regulation of filamentous growth of a population of unicellular organisms in response to heat,biological_process
89718,GO:1900432,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.",negative regulation of filamentous growth of a population of unicellular organisms in response to heat,biological_process
89719,GO:1900433,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.",positive regulation of filamentous growth of a population of unicellular organisms in response to heat,biological_process
89720,GO:1900434,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.",regulation of filamentous growth of a population of unicellular organisms in response to starvation,biological_process
89721,GO:1900436,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.",positive regulation of filamentous growth of a population of unicellular organisms in response to starvation,biological_process
89722,GO:1900437,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.",regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus,biological_process
89723,GO:1900438,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.",negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus,biological_process
89724,GO:1900439,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.",positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus,biological_process
89725,GO:1900440,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.",regulation of filamentous growth of a population of unicellular organisms in response to neutral pH,biological_process
89726,GO:1900441,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.",negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH,biological_process
89727,GO:1900442,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.",positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH,biological_process
89728,GO:1900443,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.",regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus,biological_process
89729,GO:1900444,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.",negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus,biological_process
89730,GO:1900445,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.",positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus,biological_process
89731,GO:1900449,"Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.",regulation of glutamate receptor signaling pathway,biological_process
89732,GO:1900450,"Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.",negative regulation of glutamate receptor signaling pathway,biological_process
89733,GO:1900451,"Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.",positive regulation of glutamate receptor signaling pathway,biological_process
89734,GO:1900452,"Any process that modulates the frequency, rate or extent of long term synaptic depression.",regulation of long-term synaptic depression,biological_process
89735,GO:1900453,"Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.",negative regulation of long-term synaptic depression,biological_process
89736,GO:1900454,"Any process that activates or increases the frequency, rate or extent of long term synaptic depression.",positive regulation of long-term synaptic depression,biological_process
89737,GO:1900457,"Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.",regulation of brassinosteroid mediated signaling pathway,biological_process
89738,GO:1900458,"Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.",negative regulation of brassinosteroid mediated signaling pathway,biological_process
89739,GO:1900459,"Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.",positive regulation of brassinosteroid mediated signaling pathway,biological_process
89740,GO:1900461,"Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.",positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter,biological_process
89741,GO:1900468,"Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process.",regulation of phosphatidylserine biosynthetic process,biological_process
89742,GO:1900469,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process.",negative regulation of phosphatidylserine biosynthetic process,biological_process
89743,GO:1900470,"Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process.",positive regulation of phosphatidylserine biosynthetic process,biological_process
89744,GO:1900480,"Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.",regulation of diacylglycerol biosynthetic process,biological_process
89745,GO:1900481,"Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process.",negative regulation of diacylglycerol biosynthetic process,biological_process
89746,GO:1900482,"Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.",positive regulation of diacylglycerol biosynthetic process,biological_process
89747,GO:1900483,"Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.",regulation of protein targeting to vacuolar membrane,biological_process
89748,GO:1900484,"Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.",negative regulation of protein targeting to vacuolar membrane,biological_process
89749,GO:1900485,"Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.",positive regulation of protein targeting to vacuolar membrane,biological_process
89750,GO:1900486,"Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.","positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway",biological_process
89751,GO:1900487,"Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.",regulation of [2Fe-2S] cluster assembly,biological_process
89752,GO:1900488,"Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.",negative regulation of [2Fe-2S] cluster assembly,biological_process
89753,GO:1900489,"Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly.",positive regulation of [2Fe-2S] cluster assembly,biological_process
89754,GO:1900491,"Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.",regulation of [4Fe-4S] cluster assembly,biological_process
89755,GO:1900492,"Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.",negative regulation of [4Fe-4S] cluster assembly,biological_process
89756,GO:1900493,"Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly.",positive regulation of [4Fe-4S] cluster assembly,biological_process
89757,GO:1900503,"Any process that modulates the frequency, rate or extent of cellulosome assembly.",regulation of cellulosome assembly,biological_process
89758,GO:1900504,"Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly.",negative regulation of cellulosome assembly,biological_process
89759,GO:1900505,"Any process that activates or increases the frequency, rate or extent of cellulosome assembly.",positive regulation of cellulosome assembly,biological_process
89760,GO:1900506,"Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.",regulation of iron-sulfur-molybdenum cofactor assembly,biological_process
89761,GO:1900507,"Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.",negative regulation of iron-sulfur-molybdenum cofactor assembly,biological_process
89762,GO:1900508,"Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.",positive regulation of iron-sulfur-molybdenum cofactor assembly,biological_process
89763,GO:1900512,"Any process that modulates the frequency, rate or extent of starch utilization system complex assembly.",regulation of starch utilization system complex assembly,biological_process
89764,GO:1900513,"Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly.",negative regulation of starch utilization system complex assembly,biological_process
89765,GO:1900514,"Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly.",positive regulation of starch utilization system complex assembly,biological_process
89766,GO:1900515,"Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol.",regulation of xylose catabolic process to ethanol,biological_process
89767,GO:1900516,"Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol.",negative regulation of xylose catabolic process to ethanol,biological_process
89768,GO:1900517,"Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.",positive regulation of xylose catabolic process to ethanol,biological_process
89769,GO:1900518,"Any process that modulates the frequency, rate or extent of response to pullulan.",regulation of response to pullulan,biological_process
89770,GO:1900519,"Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.",negative regulation of response to pullulan,biological_process
89771,GO:1900520,"Any process that activates or increases the frequency, rate or extent of response to pullulan.",positive regulation of response to pullulan,biological_process
89772,GO:1900521,"Any process that modulates the frequency, rate or extent of response to amylopectin.",regulation of response to amylopectin,biological_process
89773,GO:1900522,"Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.",negative regulation of response to amylopectin,biological_process
89774,GO:1900523,"Any process that activates or increases the frequency, rate or extent of response to amylopectin.",positive regulation of response to amylopectin,biological_process
89775,GO:1900535,The chemical reactions and pathways resulting in the formation of palmitic acid.,palmitic acid biosynthetic process,biological_process
89776,GO:1900540,The chemical reactions and pathways resulting in the breakdown of fumonisin.,fumonisin catabolic process,biological_process
89777,GO:1900541,The chemical reactions and pathways resulting in the formation of fumonisin.,fumonisin biosynthetic process,biological_process
89778,GO:1900542,"Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.",regulation of purine nucleotide metabolic process,biological_process
89779,GO:1900543,"Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.",negative regulation of purine nucleotide metabolic process,biological_process
89780,GO:1900544,"Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.",positive regulation of purine nucleotide metabolic process,biological_process
89781,GO:1900548,"The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.",heme B catabolic process,biological_process
89782,GO:1900550,"The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C.","N',N'',N'''-triacetylfusarinine C catabolic process",biological_process
89783,GO:1900551,"The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.","N',N'',N'''-triacetylfusarinine C biosynthetic process",biological_process
89784,GO:1900553,The chemical reactions and pathways resulting in the breakdown of asperfuranone.,asperfuranone catabolic process,biological_process
89785,GO:1900554,The chemical reactions and pathways resulting in the formation of asperfuranone.,asperfuranone biosynthetic process,biological_process
89786,GO:1900556,The chemical reactions and pathways resulting in the breakdown of emericellamide.,emericellamide catabolic process,biological_process
89787,GO:1900557,The chemical reactions and pathways resulting in the formation of emericellamide.,emericellamide biosynthetic process,biological_process
89788,GO:1900559,The chemical reactions and pathways resulting in the breakdown of austinol.,austinol catabolic process,biological_process
89789,GO:1900560,The chemical reactions and pathways resulting in the formation of austinol.,austinol biosynthetic process,biological_process
89790,GO:1900562,The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.,dehydroaustinol catabolic process,biological_process
89791,GO:1900563,The chemical reactions and pathways resulting in the formation of dehydroaustinol.,dehydroaustinol biosynthetic process,biological_process
89792,GO:1900569,The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine.,chanoclavine-I aldehyde biosynthetic process,biological_process
89793,GO:1900574,The chemical reactions and pathways resulting in the breakdown of emodin.,emodin catabolic process,biological_process
89794,GO:1900575,The chemical reactions and pathways resulting in the formation of emodin.,emodin biosynthetic process,biological_process
89795,GO:1900577,The chemical reactions and pathways resulting in the breakdown of gerfelin.,gerfelin catabolic process,biological_process
89796,GO:1900578,The chemical reactions and pathways resulting in the formation of gerfelin.,gerfelin biosynthetic process,biological_process
89797,GO:1900580,"The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.","(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process",biological_process
89798,GO:1900581,"The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.","(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process",biological_process
89799,GO:1900583,The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.,o-orsellinic acid catabolic process,biological_process
89800,GO:1900584,The chemical reactions and pathways resulting in the formation of o-orsellinic acid.,o-orsellinic acid biosynthetic process,biological_process
89801,GO:1900586,The chemical reactions and pathways resulting in the breakdown of arugosin.,arugosin catabolic process,biological_process
89802,GO:1900587,The chemical reactions and pathways resulting in the formation of arugosin.,arugosin biosynthetic process,biological_process
89803,GO:1900588,The chemical reactions and pathways involving violaceol I.,violaceol I metabolic process,biological_process
89804,GO:1900589,The chemical reactions and pathways resulting in the breakdown of violaceol I.,violaceol I catabolic process,biological_process
89805,GO:1900590,The chemical reactions and pathways resulting in the formation of violaceol I.,violaceol I biosynthetic process,biological_process
89806,GO:1900591,The chemical reactions and pathways involving violaceol II.,violaceol II metabolic process,biological_process
89807,GO:1900592,The chemical reactions and pathways resulting in the breakdown of violaceol II.,violaceol II catabolic process,biological_process
89808,GO:1900593,The chemical reactions and pathways resulting in the formation of violaceol II.,violaceol II biosynthetic process,biological_process
89809,GO:1900595,The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.,(+)-kotanin catabolic process,biological_process
89810,GO:1900596,The chemical reactions and pathways resulting in the formation of (+)-kotanin.,(+)-kotanin biosynthetic process,biological_process
89811,GO:1900598,The chemical reactions and pathways resulting in the breakdown of demethylkotanin.,demethylkotanin catabolic process,biological_process
89812,GO:1900599,The chemical reactions and pathways resulting in the formation of demethylkotanin.,demethylkotanin biosynthetic process,biological_process
89813,GO:1900601,The chemical reactions and pathways resulting in the breakdown of endocrocin.,endocrocin catabolic process,biological_process
89814,GO:1900602,The chemical reactions and pathways resulting in the formation of endocrocin.,endocrocin biosynthetic process,biological_process
89815,GO:1900604,The chemical reactions and pathways resulting in the breakdown of tensidol A.,tensidol A catabolic process,biological_process
89816,GO:1900605,The chemical reactions and pathways resulting in the formation of tensidol A.,tensidol A biosynthetic process,biological_process
89817,GO:1900607,The chemical reactions and pathways resulting in the breakdown of tensidol B.,tensidol B catabolic process,biological_process
89818,GO:1900608,The chemical reactions and pathways resulting in the formation of tensidol B.,tensidol B biosynthetic process,biological_process
89819,GO:1900610,The chemical reactions and pathways resulting in the breakdown of F-9775A.,F-9775A catabolic process,biological_process
89820,GO:1900611,The chemical reactions and pathways resulting in the formation of F-9775A.,F-9775A biosynthetic process,biological_process
89821,GO:1900613,The chemical reactions and pathways resulting in the breakdown of F-9775B.,F-9775B catabolic process,biological_process
89822,GO:1900614,The chemical reactions and pathways resulting in the formation of F-9775B.,F-9775B biosynthetic process,biological_process
89823,GO:1900616,The chemical reactions and pathways resulting in the breakdown of emericellamide A.,emericellamide A catabolic process,biological_process
89824,GO:1900617,The chemical reactions and pathways resulting in the formation of emericellamide A.,emericellamide A biosynthetic process,biological_process
89825,GO:1900618,"Any process that modulates the frequency, rate or extent of shoot morphogenesis.",regulation of shoot system morphogenesis,biological_process
89826,GO:1900623,"Any process that modulates the frequency, rate or extent of monocyte aggregation.",regulation of monocyte aggregation,biological_process
89827,GO:1900624,"Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.",negative regulation of monocyte aggregation,biological_process
89828,GO:1900625,"Any process that activates or increases the frequency, rate or extent of monocyte aggregation.",positive regulation of monocyte aggregation,biological_process
89829,GO:1900626,"Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.",regulation of arugosin biosynthetic process,biological_process
89830,GO:1900627,"Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.",negative regulation of arugosin biosynthetic process,biological_process
89831,GO:1900628,"Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process.",positive regulation of arugosin biosynthetic process,biological_process
89832,GO:1900630,The chemical reactions and pathways resulting in the formation of methanophenazine.,methanophenazine biosynthetic process,biological_process
89833,GO:1900632,The chemical reactions and pathways resulting in the formation of tridecane.,tridecane biosynthetic process,biological_process
89834,GO:1900634,The chemical reactions and pathways resulting in the formation of pentadecane.,pentadecane biosynthetic process,biological_process
89835,GO:1900636,The chemical reactions and pathways resulting in the formation of heptadecane.,heptadecane biosynthetic process,biological_process
89836,GO:1900637,"Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process.",regulation of asperfuranone biosynthetic process,biological_process
89837,GO:1900638,"Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process.",negative regulation of asperfuranone biosynthetic process,biological_process
89838,GO:1900639,"Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process.",positive regulation of asperfuranone biosynthetic process,biological_process
89839,GO:1900640,"Any process that modulates the frequency, rate or extent of austinol biosynthetic process.",regulation of austinol biosynthetic process,biological_process
89840,GO:1900641,"Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.",negative regulation of austinol biosynthetic process,biological_process
89841,GO:1900642,"Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.",positive regulation of austinol biosynthetic process,biological_process
89842,GO:1900646,"Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.",regulation of chanoclavine-I aldehyde biosynthetic process,biological_process
89843,GO:1900647,"Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.",negative regulation of chanoclavine-I aldehyde biosynthetic process,biological_process
89844,GO:1900648,"Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.",positive regulation of chanoclavine-I aldehyde biosynthetic process,biological_process
89845,GO:1900649,"Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.",regulation of dehydroaustinol biosynthetic process,biological_process
89846,GO:1900650,"Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.",negative regulation of dehydroaustinol biosynthetic process,biological_process
89847,GO:1900651,"Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process.",positive regulation of dehydroaustinol biosynthetic process,biological_process
89848,GO:1900652,"Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.",regulation of demethylkotanin biosynthetic process,biological_process
89849,GO:1900653,"Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.",negative regulation of demethylkotanin biosynthetic process,biological_process
89850,GO:1900654,"Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process.",positive regulation of demethylkotanin biosynthetic process,biological_process
89851,GO:1900658,"Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process.",regulation of emericellamide biosynthetic process,biological_process
89852,GO:1900659,"Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process.",negative regulation of emericellamide biosynthetic process,biological_process
89853,GO:1900660,"Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process.",positive regulation of emericellamide biosynthetic process,biological_process
89854,GO:1900661,"Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process.",regulation of emericellamide A biosynthetic process,biological_process
89855,GO:1900662,"Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process.",negative regulation of emericellamide A biosynthetic process,biological_process
89856,GO:1900663,"Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process.",positive regulation of emericellamide A biosynthetic process,biological_process
89857,GO:1900664,"Any process that modulates the frequency, rate or extent of emodin biosynthetic process.",regulation of emodin biosynthetic process,biological_process
89858,GO:1900665,"Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.",negative regulation of emodin biosynthetic process,biological_process
89859,GO:1900666,"Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process.",positive regulation of emodin biosynthetic process,biological_process
89860,GO:1900667,"Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.",regulation of endocrocin biosynthetic process,biological_process
89861,GO:1900668,"Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process.",negative regulation of endocrocin biosynthetic process,biological_process
89862,GO:1900669,"Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process.",positive regulation of endocrocin biosynthetic process,biological_process
89863,GO:1900670,"Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process.",regulation of F-9775A biosynthetic process,biological_process
89864,GO:1900671,"Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process.",negative regulation of F-9775A biosynthetic process,biological_process
89865,GO:1900672,"Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.",positive regulation of F-9775A biosynthetic process,biological_process
89866,GO:1900673,The chemical reactions and pathways involving olefin.,olefin metabolic process,biological_process
89867,GO:1900674,The chemical reactions and pathways resulting in the formation of olefin.,olefin biosynthetic process,biological_process
89868,GO:1900675,"Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process.",regulation of F-9775B biosynthetic process,biological_process
89869,GO:1900676,"Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process.",negative regulation of F-9775B biosynthetic process,biological_process
89870,GO:1900677,"Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process.",positive regulation of F-9775B biosynthetic process,biological_process
89871,GO:1900678,"Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.",regulation of ferricrocin biosynthetic process,biological_process
89872,GO:1900679,"Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process.",negative regulation of ferricrocin biosynthetic process,biological_process
89873,GO:1900680,"Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process.",positive regulation of ferricrocin biosynthetic process,biological_process
89874,GO:1900683,"Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process.",regulation of fumonisin biosynthetic process,biological_process
89875,GO:1900684,"Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process.",negative regulation of fumonisin biosynthetic process,biological_process
89876,GO:1900685,"Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process.",positive regulation of fumonisin biosynthetic process,biological_process
89877,GO:1900686,"Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process.",regulation of gerfelin biosynthetic process,biological_process
89878,GO:1900687,"Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.",negative regulation of gerfelin biosynthetic process,biological_process
89879,GO:1900688,"Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process.",positive regulation of gerfelin biosynthetic process,biological_process
89880,GO:1900689,"Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process.",regulation of gliotoxin biosynthetic process,biological_process
89881,GO:1900690,"Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process.",negative regulation of gliotoxin biosynthetic process,biological_process
89882,GO:1900691,"Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process.",positive regulation of gliotoxin biosynthetic process,biological_process
89883,GO:1900692,"Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.",regulation of (+)-kotanin biosynthetic process,biological_process
89884,GO:1900693,"Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.",negative regulation of (+)-kotanin biosynthetic process,biological_process
89885,GO:1900694,"Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.",positive regulation of (+)-kotanin biosynthetic process,biological_process
89886,GO:1900695,"Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.","regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process",biological_process
89887,GO:1900696,"Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.","negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process",biological_process
89888,GO:1900697,"Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.","positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process",biological_process
89889,GO:1900698,"Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process.",regulation of o-orsellinic acid biosynthetic process,biological_process
89890,GO:1900699,"Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process.",negative regulation of o-orsellinic acid biosynthetic process,biological_process
89891,GO:1900700,"Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process.",positive regulation of o-orsellinic acid biosynthetic process,biological_process
89892,GO:1900701,"Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.",regulation of orcinol biosynthetic process,biological_process
89893,GO:1900702,"Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.",negative regulation of orcinol biosynthetic process,biological_process
89894,GO:1900703,"Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process.",positive regulation of orcinol biosynthetic process,biological_process
89895,GO:1900704,"Any process that modulates the frequency, rate or extent of siderophore biosynthetic process.",regulation of siderophore biosynthetic process,biological_process
89896,GO:1900705,"Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process.",negative regulation of siderophore biosynthetic process,biological_process
89897,GO:1900706,"Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process.",positive regulation of siderophore biosynthetic process,biological_process
89898,GO:1900707,"Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process.",regulation of tensidol A biosynthetic process,biological_process
89899,GO:1900708,"Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process.",negative regulation of tensidol A biosynthetic process,biological_process
89900,GO:1900709,"Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process.",positive regulation of tensidol A biosynthetic process,biological_process
89901,GO:1900710,"Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process.",regulation of tensidol B biosynthetic process,biological_process
89902,GO:1900711,"Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process.",negative regulation of tensidol B biosynthetic process,biological_process
89903,GO:1900712,"Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process.",positive regulation of tensidol B biosynthetic process,biological_process
89904,GO:1900713,"Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.",regulation of violaceol I biosynthetic process,biological_process
89905,GO:1900714,"Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.",negative regulation of violaceol I biosynthetic process,biological_process
89906,GO:1900715,"Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process.",positive regulation of violaceol I biosynthetic process,biological_process
89907,GO:1900716,"Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.",regulation of violaceol II biosynthetic process,biological_process
89908,GO:1900717,"Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.",negative regulation of violaceol II biosynthetic process,biological_process
89909,GO:1900718,"Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process.",positive regulation of violaceol II biosynthetic process,biological_process
89910,GO:1900719,"Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.",regulation of uterine smooth muscle relaxation,biological_process
89911,GO:1900720,"Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.",negative regulation of uterine smooth muscle relaxation,biological_process
89912,GO:1900721,"Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.",positive regulation of uterine smooth muscle relaxation,biological_process
89913,GO:1900722,"Any process that modulates the frequency, rate or extent of protein adenylylation.",regulation of protein adenylylation,biological_process
89914,GO:1900723,"Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.",negative regulation of protein adenylylation,biological_process
89915,GO:1900724,"Any process that activates or increases the frequency, rate or extent of protein adenylylation.",positive regulation of protein adenylylation,biological_process
89916,GO:1900726,The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.,osmoregulated periplasmic glucan catabolic process,biological_process
89917,GO:1900727,The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.,osmoregulated periplasmic glucan biosynthetic process,biological_process
89918,GO:1900729,"Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.",regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway,biological_process
89919,GO:1900730,"Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.",negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway,biological_process
89920,GO:1900731,"Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.",positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway,biological_process
89921,GO:1900732,"Any process that modulates the frequency, rate or extent of polyketide biosynthetic process.",regulation of polyketide biosynthetic process,biological_process
89922,GO:1900733,"Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process.",negative regulation of polyketide biosynthetic process,biological_process
89923,GO:1900734,"Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process.",positive regulation of polyketide biosynthetic process,biological_process
89924,GO:1900735,"Any process that activates or increases the frequency, rate or extent of flocculation.",positive regulation of flocculation,biological_process
89925,GO:1900736,"Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.",regulation of phospholipase C-activating G protein-coupled receptor signaling pathway,biological_process
89926,GO:1900737,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.",negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway,biological_process
89927,GO:1900738,"Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.",positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway,biological_process
89928,GO:1900741,"Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.",regulation of filamentous growth of a population of unicellular organisms in response to pH,biological_process
89929,GO:1900742,"Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.",negative regulation of filamentous growth of a population of unicellular organisms in response to pH,biological_process
89930,GO:1900743,"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.",positive regulation of filamentous growth of a population of unicellular organisms in response to pH,biological_process
89931,GO:1900744,"Any process that modulates the frequency, rate or extent of p38MAPK cascade.",regulation of p38MAPK cascade,biological_process
89932,GO:1900745,"Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.",positive regulation of p38MAPK cascade,biological_process
89933,GO:1900746,"Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.",regulation of vascular endothelial growth factor signaling pathway,biological_process
89934,GO:1900747,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.",negative regulation of vascular endothelial growth factor signaling pathway,biological_process
89935,GO:1900748,"Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.",positive regulation of vascular endothelial growth factor signaling pathway,biological_process
89936,GO:1900749,"The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",(R)-carnitine transport,biological_process
89937,GO:1900750,Binding to an oligopeptide.,oligopeptide binding,molecular_function
89938,GO:1900751,"The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",4-(trimethylammonio)butanoate transport,biological_process
89939,GO:1900752,"The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",malonic acid transport,biological_process
89940,GO:1900753,"The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",doxorubicin transport,biological_process
89941,GO:1900754,"The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",4-hydroxyphenylacetate transport,biological_process
89942,GO:1900756,Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation.,protein processing in phagocytic vesicle,biological_process
89943,GO:1900760,"Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.",negative regulation of sterigmatocystin biosynthetic process,biological_process
89944,GO:1900762,The chemical reactions and pathways resulting in the breakdown of averantin.,averantin catabolic process,biological_process
89945,GO:1900763,The chemical reactions and pathways resulting in the formation of averantin.,averantin biosynthetic process,biological_process
89946,GO:1900765,The chemical reactions and pathways resulting in the breakdown of emericellin.,emericellin catabolic process,biological_process
89947,GO:1900766,The chemical reactions and pathways resulting in the formation of emericellin.,emericellin biosynthetic process,biological_process
89948,GO:1900768,The chemical reactions and pathways resulting in the breakdown of fonsecin.,fonsecin catabolic process,biological_process
89949,GO:1900769,The chemical reactions and pathways resulting in the formation of fonsecin.,fonsecin biosynthetic process,biological_process
89950,GO:1900772,The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B.,fumitremorgin B biosynthetic process,biological_process
89951,GO:1900781,The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C.,fumiquinazoline C biosynthetic process,biological_process
89952,GO:1900786,The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone.,naphtho-gamma-pyrone catabolic process,biological_process
89953,GO:1900787,The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.,naphtho-gamma-pyrone biosynthetic process,biological_process
89954,GO:1900789,The chemical reactions and pathways resulting in the breakdown of pseurotin A.,pseurotin A catabolic process,biological_process
89955,GO:1900790,The chemical reactions and pathways resulting in the formation of pseurotin A.,pseurotin A biosynthetic process,biological_process
89956,GO:1900792,The chemical reactions and pathways resulting in the breakdown of shamixanthone.,shamixanthone catabolic process,biological_process
89957,GO:1900793,The chemical reactions and pathways resulting in the formation of shamixanthone.,shamixanthone biosynthetic process,biological_process
89958,GO:1900796,The chemical reactions and pathways resulting in the formation of terrequinone A.,terrequinone A biosynthetic process,biological_process
89959,GO:1900801,The chemical reactions and pathways resulting in the breakdown of cspyrone B1.,cspyrone B1 catabolic process,biological_process
89960,GO:1900802,The chemical reactions and pathways resulting in the formation of cspyrone B1.,cspyrone B1 biosynthetic process,biological_process
89961,GO:1900805,"The chemical reactions and pathways resulting in the formation of brevianamide F. Brevianamide F is the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by some fungi.",brevianamide F biosynthetic process,biological_process
89962,GO:1900809,"The chemical reactions and pathways resulting in the formation of fumigaclavine C, a fungal ergot alkaloid.",fumigaclavine C biosynthetic process,biological_process
89963,GO:1900811,The chemical reactions and pathways resulting in the breakdown of helvolic acid.,helvolic acid catabolic process,biological_process
89964,GO:1900812,The chemical reactions and pathways resulting in the formation of helvolic acid.,helvolic acid biosynthetic process,biological_process
89965,GO:1900813,The chemical reactions and pathways involving monodictyphenone.,monodictyphenone metabolic process,biological_process
89966,GO:1900814,The chemical reactions and pathways resulting in the breakdown of monodictyphenone.,monodictyphenone catabolic process,biological_process
89967,GO:1900815,The chemical reactions and pathways resulting in the formation of monodictyphenone.,monodictyphenone biosynthetic process,biological_process
89968,GO:1900817,The chemical reactions and pathways resulting in the breakdown of ochratoxin A.,ochratoxin A catabolic process,biological_process
89969,GO:1900818,The chemical reactions and pathways resulting in the formation of ochratoxin A.,ochratoxin A biosynthetic process,biological_process
89970,GO:1900819,The chemical reactions and pathways involving orlandin.,orlandin metabolic process,biological_process
89971,GO:1900820,The chemical reactions and pathways resulting in the breakdown of orlandin.,orlandin catabolic process,biological_process
89972,GO:1900821,The chemical reactions and pathways resulting in the formation of orlandin.,orlandin biosynthetic process,biological_process
89973,GO:1900822,"Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.",regulation of ergot alkaloid biosynthetic process,biological_process
89974,GO:1900823,"Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.",negative regulation of ergot alkaloid biosynthetic process,biological_process
89975,GO:1900824,"Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process.",positive regulation of ergot alkaloid biosynthetic process,biological_process
89976,GO:1900825,"Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.",regulation of membrane depolarization during cardiac muscle cell action potential,biological_process
89977,GO:1900826,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.",negative regulation of membrane depolarization during cardiac muscle cell action potential,biological_process
89978,GO:1900827,"Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.",positive regulation of membrane depolarization during cardiac muscle cell action potential,biological_process
89979,GO:1900834,"Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.",regulation of emericellin biosynthetic process,biological_process
89980,GO:1900835,"Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process.",negative regulation of emericellin biosynthetic process,biological_process
89981,GO:1900836,"Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.",positive regulation of emericellin biosynthetic process,biological_process
89982,GO:1900837,"Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.",regulation of fumigaclavine C biosynthetic process,biological_process
89983,GO:1900838,"Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process.",negative regulation of fumigaclavine C biosynthetic process,biological_process
89984,GO:1900839,"Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process.",positive regulation of fumigaclavine C biosynthetic process,biological_process
89985,GO:1900840,"Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process.",regulation of helvolic acid biosynthetic process,biological_process
89986,GO:1900841,"Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.",negative regulation of helvolic acid biosynthetic process,biological_process
89987,GO:1900842,"Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.",positive regulation of helvolic acid biosynthetic process,biological_process
89988,GO:1900843,"Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process.",regulation of monodictyphenone biosynthetic process,biological_process
89989,GO:1900844,"Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process.",negative regulation of monodictyphenone biosynthetic process,biological_process
89990,GO:1900845,"Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process.",positive regulation of monodictyphenone biosynthetic process,biological_process
89991,GO:1900846,"Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.",regulation of naphtho-gamma-pyrone biosynthetic process,biological_process
89992,GO:1900847,"Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.",negative regulation of naphtho-gamma-pyrone biosynthetic process,biological_process
89993,GO:1900848,"Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.",positive regulation of naphtho-gamma-pyrone biosynthetic process,biological_process
89994,GO:1900849,"Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.",regulation of pseurotin A biosynthetic process,biological_process
89995,GO:1900850,"Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.",negative regulation of pseurotin A biosynthetic process,biological_process
89996,GO:1900851,"Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process.",positive regulation of pseurotin A biosynthetic process,biological_process
89997,GO:1900854,"Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process.",positive regulation of terrequinone A biosynthetic process,biological_process
89998,GO:1900864,Any RNA modification that takes place in mitochondrion.,mitochondrial RNA modification,biological_process
89999,GO:1900865,Any RNA modification that takes place in chloroplast.,chloroplast RNA modification,biological_process
90000,GO:1900866,"The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycolate transport,biological_process
90001,GO:1900868,The chemical reactions and pathways resulting in the formation of sarcinapterin.,sarcinapterin biosynthetic process,biological_process
90002,GO:1900871,The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.,chloroplast mRNA modification,biological_process
90003,GO:1900873,The chemical reactions and pathways resulting in the formation of pentadec-1-ene.,pentadec-1-ene biosynthetic process,biological_process
90004,GO:1900875,The chemical reactions and pathways resulting in the formation of heptadec-1-ene.,heptadec-1-ene biosynthetic process,biological_process
90005,GO:1900877,The chemical reactions and pathways resulting in the formation of nonadec-1-ene.,nonadec-1-ene biosynthetic process,biological_process
90006,GO:1900884,"Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.",regulation of tridecane biosynthetic process,biological_process
90007,GO:1900885,"Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.",negative regulation of tridecane biosynthetic process,biological_process
90008,GO:1900886,"Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process.",positive regulation of tridecane biosynthetic process,biological_process
90009,GO:1900887,"Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.",regulation of pentadecane biosynthetic process,biological_process
90010,GO:1900888,"Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.",negative regulation of pentadecane biosynthetic process,biological_process
90011,GO:1900889,"Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process.",positive regulation of pentadecane biosynthetic process,biological_process
90012,GO:1900896,"Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.",regulation of heptadecane biosynthetic process,biological_process
90013,GO:1900897,"Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.",negative regulation of heptadecane biosynthetic process,biological_process
90014,GO:1900898,"Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.",positive regulation of heptadecane biosynthetic process,biological_process
90015,GO:1900902,"Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.",regulation of hexadecanal biosynthetic process,biological_process
90016,GO:1900903,"Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.",negative regulation of hexadecanal biosynthetic process,biological_process
90017,GO:1900904,"Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.",positive regulation of hexadecanal biosynthetic process,biological_process
90018,GO:1900911,"Any process that modulates the frequency, rate or extent of olefin biosynthetic process.",regulation of olefin biosynthetic process,biological_process
90019,GO:1900912,"Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process.",negative regulation of olefin biosynthetic process,biological_process
90020,GO:1900913,"Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.",positive regulation of olefin biosynthetic process,biological_process
90021,GO:1900923,"Any process that modulates the frequency, rate or extent of glycine import into a cell.",regulation of glycine import across plasma membrane,biological_process
90022,GO:1900924,"Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.",negative regulation of glycine import across plasma membrane,biological_process
90023,GO:1900925,"Any process that activates or increases the frequency, rate or extent of glycine import.",positive regulation of glycine import across plasma membrane,biological_process
90024,GO:1900926,"Any process that modulates the frequency, rate or extent of L-threonine import into cell.",regulation of L-threonine import across plasma membrane,biological_process
90025,GO:1900927,"Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell.",negative regulation of L-threonine import across plasma membrane,biological_process
90026,GO:1900928,"Any process that activates or increases the frequency, rate or extent of L-threonine import into cell.",positive regulation of L-threonine import across plasma membrane,biological_process
90027,GO:1900929,"Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.",regulation of L-tyrosine import across plasma membrane,biological_process
90028,GO:1900930,"Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.",negative regulation of L-tyrosine import across plasma membrane,biological_process
90029,GO:1900931,"Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.",positive regulation of L-tyrosine import across plasma membrane,biological_process
90030,GO:1900949,"Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process.","positive regulation of isopentenyl diphosphate biosynthetic process, methylerythritol phosphate pathway",biological_process
90031,GO:1900962,"Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.",regulation of methanophenazine biosynthetic process,biological_process
90032,GO:1900963,"Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process.",negative regulation of methanophenazine biosynthetic process,biological_process
90033,GO:1900964,"Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.",positive regulation of methanophenazine biosynthetic process,biological_process
90034,GO:1900971,"Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.",regulation of sarcinapterin biosynthetic process,biological_process
90035,GO:1900972,"Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.",negative regulation of sarcinapterin biosynthetic process,biological_process
90036,GO:1900973,"Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process.",positive regulation of sarcinapterin biosynthetic process,biological_process
90037,GO:1900980,"Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.",regulation of phenazine biosynthetic process,biological_process
90038,GO:1900981,"Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.",negative regulation of phenazine biosynthetic process,biological_process
90039,GO:1900982,"Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process.",positive regulation of phenazine biosynthetic process,biological_process
90040,GO:1900985,The chemical reactions and pathways resulting in the formation of vindoline.,vindoline biosynthetic process,biological_process
90041,GO:1900988,The chemical reactions and pathways resulting in the formation of ajmaline.,ajmaline biosynthetic process,biological_process
90042,GO:1900991,The chemical reactions and pathways resulting in the formation of scopolamine.,scopolamine biosynthetic process,biological_process
90043,GO:1900994,The chemical reactions and pathways resulting in the formation of (-)-secologanin.,(-)-secologanin biosynthetic process,biological_process
90044,GO:1900995,"Binding to ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.",ubiquinone-6 binding,molecular_function
90045,GO:1900996,The chemical reactions and pathways resulting in the breakdown of benzene.,benzene catabolic process,biological_process
90046,GO:1900997,The chemical reactions and pathways resulting in the formation of benzene.,benzene biosynthetic process,biological_process
90047,GO:1900998,The chemical reactions and pathways resulting in the breakdown of nitrobenzene.,nitrobenzene catabolic process,biological_process
90048,GO:1900999,The chemical reactions and pathways resulting in the formation of nitrobenzene.,nitrobenzene biosynthetic process,biological_process
90049,GO:1901000,"Any process that modulates the frequency, rate or extent of response to salt stress.",regulation of response to salt stress,biological_process
90050,GO:1901001,"Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.",negative regulation of response to salt stress,biological_process
90051,GO:1901002,"Any process that activates or increases the frequency, rate or extent of response to salt stress.",positive regulation of response to salt stress,biological_process
90052,GO:1901003,"Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.",negative regulation of fermentation,biological_process
90053,GO:1901009,The chemical reactions and pathways resulting in the formation of (S)-scoulerine.,(S)-scoulerine biosynthetic process,biological_process
90054,GO:1901012,The chemical reactions and pathways resulting in the formation of (S)-reticuline.,(S)-reticuline biosynthetic process,biological_process
90055,GO:1901015,The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine.,3alpha(S)-strictosidine biosynthetic process,biological_process
90056,GO:1901017,"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.",negative regulation of potassium ion transmembrane transporter activity,biological_process
90057,GO:1901020,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.",negative regulation of calcium ion transmembrane transporter activity,biological_process
90058,GO:1901022,The chemical reactions and pathways involving 4-hydroxyphenylacetate.,4-hydroxyphenylacetate metabolic process,biological_process
90059,GO:1901023,The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.,4-hydroxyphenylacetate catabolic process,biological_process
90060,GO:1901024,The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate.,4-hydroxyphenylacetate biosynthetic process,biological_process
90061,GO:1901026,"The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.",ripoptosome assembly involved in necroptotic process,biological_process
90062,GO:1901027,The chemical reactions and pathways resulting in the breakdown of dextrin.,dextrin catabolic process,biological_process
90063,GO:1901028,"Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.",regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,biological_process
90064,GO:1901029,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.",negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,biological_process
90065,GO:1901030,"Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.",positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,biological_process
90066,GO:1901031,"Any process that modulates the frequency, rate or extent of response to reactive oxygen species.",regulation of response to reactive oxygen species,biological_process
90067,GO:1901032,"Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.",negative regulation of response to reactive oxygen species,biological_process
90068,GO:1901033,"Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species.",positive regulation of response to reactive oxygen species,biological_process
90069,GO:1901034,"Any process that modulates the frequency, rate or extent of L-glutamine import into cell.",regulation of L-glutamine import across plasma membrane,biological_process
90070,GO:1901035,"Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell.",negative regulation of L-glutamine import across plasma membrane,biological_process
90071,GO:1901036,"Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell.",positive regulation of L-glutamine import across plasma membrane,biological_process
90072,GO:1901038,The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.,cyanidin 3-O-glucoside metabolic process,biological_process
90073,GO:1901039,"Any process that modulates the frequency, rate or extent of peptide antigen transport.",regulation of peptide antigen transport,biological_process
90074,GO:1901040,"Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport.",negative regulation of peptide antigen transport,biological_process
90075,GO:1901041,"Any process that activates or increases the frequency, rate or extent of peptide antigen transport.",positive regulation of peptide antigen transport,biological_process
90076,GO:1901045,"Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.",negative regulation of egg-laying behavior,biological_process
90077,GO:1901046,"Any process that activates or increases the frequency, rate or extent of oviposition.",positive regulation of egg-laying behavior,biological_process
90078,GO:1901051,The chemical reactions and pathways resulting in the formation of atropine. Atropine is the racemic mixture of hyoscyamine.,atropine biosynthetic process,biological_process
90079,GO:1901057,The chemical reactions and pathways resulting in the formation of trimethylenediamine.,trimethylenediamine biosynthetic process,biological_process
90080,GO:1901059,The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.,p-hydroxyphenyl lignin catabolic process,biological_process
90081,GO:1901060,The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin.,p-hydroxyphenyl lignin biosynthetic process,biological_process
90082,GO:1901062,The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.,guaiacyl lignin catabolic process,biological_process
90083,GO:1901063,The chemical reactions and pathways resulting in the formation of guaiacyl lignin.,guaiacyl lignin biosynthetic process,biological_process
90084,GO:1901065,The chemical reactions and pathways resulting in the breakdown of syringal lignin.,syringal lignin catabolic process,biological_process
90085,GO:1901066,The chemical reactions and pathways resulting in the formation of syringal lignin.,syringal lignin biosynthetic process,biological_process
90086,GO:1901067,The chemical reactions and pathways resulting in the breakdown of ferulate.,ferulate catabolic process,biological_process
90087,GO:1901069,The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).,guanosine-containing compound catabolic process,biological_process
90088,GO:1901070,The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines).,guanosine-containing compound biosynthetic process,biological_process
90089,GO:1901072,The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).,glucosamine-containing compound catabolic process,biological_process
90090,GO:1901073,The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).,glucosamine-containing compound biosynthetic process,biological_process
90091,GO:1901074,"Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.",regulation of engulfment of apoptotic cell,biological_process
90092,GO:1901075,"Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.",negative regulation of engulfment of apoptotic cell,biological_process
90093,GO:1901076,"Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.",positive regulation of engulfment of apoptotic cell,biological_process
90094,GO:1901077,"Any process that modulates the frequency, rate or extent of relaxation of muscle.",regulation of relaxation of muscle,biological_process
90095,GO:1901078,"Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.",negative regulation of relaxation of muscle,biological_process
90096,GO:1901079,"Any process that activates or increases the frequency, rate or extent of relaxation of muscle.",positive regulation of relaxation of muscle,biological_process
90097,GO:1901080,"Any process that modulates the frequency, rate or extent of relaxation of smooth muscle.",regulation of relaxation of smooth muscle,biological_process
90098,GO:1901081,"Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.",negative regulation of relaxation of smooth muscle,biological_process
90099,GO:1901082,"Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.",positive regulation of relaxation of smooth muscle,biological_process
90100,GO:1901085,The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid.,pyrrolizidine alkaloid biosynthetic process,biological_process
90101,GO:1901086,The chemical reactions and pathways involving benzylpenicillin.,benzylpenicillin metabolic process,biological_process
90102,GO:1901087,The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.,benzylpenicillin catabolic process,biological_process
90103,GO:1901088,The chemical reactions and pathways resulting in the formation of benzylpenicillin.,benzylpenicillin biosynthetic process,biological_process
90104,GO:1901090,"Any process that modulates the frequency, rate or extent of protein tetramerization.",regulation of protein tetramerization,biological_process
90105,GO:1901091,"Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization.",negative regulation of protein tetramerization,biological_process
90106,GO:1901092,"Any process that activates or increases the frequency, rate or extent of protein tetramerization.",positive regulation of protein tetramerization,biological_process
90107,GO:1901093,"Any process that modulates the frequency, rate or extent of protein homotetramerization.",regulation of protein homotetramerization,biological_process
90108,GO:1901094,"Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.",negative regulation of protein homotetramerization,biological_process
90109,GO:1901095,"Any process that activates or increases the frequency, rate or extent of protein homotetramerization.",positive regulation of protein homotetramerization,biological_process
90110,GO:1901096,"Any process that modulates the frequency, rate or extent of autophagosome maturation.",regulation of autophagosome maturation,biological_process
90111,GO:1901097,"Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.",negative regulation of autophagosome maturation,biological_process
90112,GO:1901098,"Any process that activates or increases the frequency, rate or extent of autophagosome maturation.",positive regulation of autophagosome maturation,biological_process
90113,GO:1901099,"Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.",negative regulation of signal transduction in absence of ligand,biological_process
90114,GO:1901103,The chemical reactions and pathways resulting in the formation of gramicidin S.,gramicidin S biosynthetic process,biological_process
90115,GO:1901105,The chemical reactions and pathways resulting in the breakdown of tetracenomycin C.,tetracenomycin C catabolic process,biological_process
90116,GO:1901106,The chemical reactions and pathways resulting in the formation of tetracenomycin C.,tetracenomycin C biosynthetic process,biological_process
90117,GO:1901108,The chemical reactions and pathways resulting in the breakdown of granaticin.,granaticin catabolic process,biological_process
90118,GO:1901109,The chemical reactions and pathways resulting in the formation of granaticin.,granaticin biosynthetic process,biological_process
90119,GO:1901111,The chemical reactions and pathways resulting in the breakdown of actinorhodin.,actinorhodin catabolic process,biological_process
90120,GO:1901112,The chemical reactions and pathways resulting in the formation of actinorhodin.,actinorhodin biosynthetic process,biological_process
90121,GO:1901114,The chemical reactions and pathways resulting in the breakdown of erythromycin.,erythromycin catabolic process,biological_process
90122,GO:1901115,The chemical reactions and pathways resulting in the formation of erythromycin.,erythromycin biosynthetic process,biological_process
90123,GO:1901117,The chemical reactions and pathways resulting in the breakdown of cephamycin C.,cephamycin C catabolic process,biological_process
90124,GO:1901118,The chemical reactions and pathways resulting in the formation of cephamycin C.,cephamycin C biosynthetic process,biological_process
90125,GO:1901120,The chemical reactions and pathways resulting in the breakdown of tobramycin.,tobramycin catabolic process,biological_process
90126,GO:1901121,The chemical reactions and pathways resulting in the formation of tobramycin.,tobramycin biosynthetic process,biological_process
90127,GO:1901123,The chemical reactions and pathways resulting in the breakdown of bacitracin A.,bacitracin A catabolic process,biological_process
90128,GO:1901124,The chemical reactions and pathways resulting in the formation of bacitracin A.,bacitracin A biosynthetic process,biological_process
90129,GO:1901126,The chemical reactions and pathways resulting in the breakdown of candicidin.,candicidin catabolic process,biological_process
90130,GO:1901127,The chemical reactions and pathways resulting in the formation of candicidin.,candicidin biosynthetic process,biological_process
90131,GO:1901130,The chemical reactions and pathways resulting in the formation of gentamycin.,gentamycin biosynthetic process,biological_process
90132,GO:1901132,The chemical reactions and pathways resulting in the breakdown of kanamycin.,kanamycin catabolic process,biological_process
90133,GO:1901133,The chemical reactions and pathways resulting in the formation of kanamycin.,kanamycin biosynthetic process,biological_process
90134,GO:1901135,The chemical reactions and pathways involving carbohydrate derivative.,carbohydrate derivative metabolic process,biological_process
90135,GO:1901136,The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.,carbohydrate derivative catabolic process,biological_process
90136,GO:1901137,The chemical reactions and pathways resulting in the formation of carbohydrate derivative.,carbohydrate derivative biosynthetic process,biological_process
90137,GO:1901140,"The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",p-coumaryl alcohol transport,biological_process
90138,GO:1901141,"Any process that modulates the frequency, rate or extent of lignin biosynthetic process.",regulation of lignin biosynthetic process,biological_process
90139,GO:1901142,The chemical reactions and pathways involving insulin.,insulin metabolic process,biological_process
90140,GO:1901143,The chemical reactions and pathways resulting in the breakdown of insulin.,insulin catabolic process,biological_process
90141,GO:1901145,Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.,mesenchymal cell apoptotic process involved in nephron morphogenesis,biological_process
90142,GO:1901148,"Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.",gene expression involved in extracellular matrix organization,biological_process
90143,GO:1901149,Binding to salicylic acid.,salicylic acid binding,molecular_function
90144,GO:1901151,The chemical reactions and pathways resulting in the breakdown of vistamycin.,vistamycin catabolic process,biological_process
90145,GO:1901152,The chemical reactions and pathways resulting in the formation of vistamycin.,vistamycin biosynthetic process,biological_process
90146,GO:1901154,The chemical reactions and pathways resulting in the breakdown of paromomycin.,paromomycin catabolic process,biological_process
90147,GO:1901155,The chemical reactions and pathways resulting in the formation of paromomycin.,paromomycin biosynthetic process,biological_process
90148,GO:1901158,The chemical reactions and pathways resulting in the formation of neomycin.,neomycin biosynthetic process,biological_process
90149,GO:1901159,The chemical reactions and pathways resulting in the formation of D-xylulose 5-phosphate.,D-xylulose 5-phosphate biosynthetic process,biological_process
90150,GO:1901161,The chemical reactions and pathways resulting in the breakdown of primary amino compound.,primary amino compound catabolic process,biological_process
90151,GO:1901162,The chemical reactions and pathways resulting in the formation of primary amino compound.,primary amino compound biosynthetic process,biological_process
90152,GO:1901163,"Any process that modulates the frequency, rate or extent of trophoblast cell migration.",regulation of trophoblast cell migration,biological_process
90153,GO:1901164,"Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.",negative regulation of trophoblast cell migration,biological_process
90154,GO:1901165,"Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.",positive regulation of trophoblast cell migration,biological_process
90155,GO:1901166,Any neural crest cell migration that is involved in autonomic nervous system development.,neural crest cell migration involved in autonomic nervous system development,biological_process
90156,GO:1901168,The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.,3-chlorocatechol catabolic process,biological_process
90157,GO:1901169,The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.,3-chlorocatechol biosynthetic process,biological_process
90158,GO:1901170,The chemical reactions and pathways resulting in the breakdown of naphthalene.,naphthalene catabolic process,biological_process
90159,GO:1901173,The chemical reactions and pathways resulting in the breakdown of phytoene.,phytoene catabolic process,biological_process
90160,GO:1901174,The chemical reactions and pathways resulting in the formation of phytoene.,phytoene biosynthetic process,biological_process
90161,GO:1901176,The chemical reactions and pathways resulting in the breakdown of lycopene.,lycopene catabolic process,biological_process
90162,GO:1901177,The chemical reactions and pathways resulting in the formation of lycopene.,lycopene biosynthetic process,biological_process
90163,GO:1901179,The chemical reactions and pathways resulting in the breakdown of spheroidene.,spheroidene catabolic process,biological_process
90164,GO:1901180,The chemical reactions and pathways resulting in the formation of spheroidene.,spheroidene biosynthetic process,biological_process
90165,GO:1901181,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.",negative regulation of cellular response to caffeine,biological_process
90166,GO:1901183,"Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.",positive regulation of camalexin biosynthetic process,biological_process
90167,GO:1901184,"Any process that modulates the frequency, rate or extent of ERBB signaling pathway.",regulation of ERBB signaling pathway,biological_process
90168,GO:1901185,"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.",negative regulation of ERBB signaling pathway,biological_process
90169,GO:1901186,"Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.",positive regulation of ERBB signaling pathway,biological_process
90170,GO:1901187,"Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.",regulation of ephrin receptor signaling pathway,biological_process
90171,GO:1901188,"Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway.",negative regulation of ephrin receptor signaling pathway,biological_process
90172,GO:1901189,"Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.",positive regulation of ephrin receptor signaling pathway,biological_process
90173,GO:1901190,"Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.",regulation of formation of translation initiation ternary complex,biological_process
90174,GO:1901191,"Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.",negative regulation of formation of translation initiation ternary complex,biological_process
90175,GO:1901192,"Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.",positive regulation of formation of translation initiation ternary complex,biological_process
90176,GO:1901193,"Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex.",regulation of formation of translation preinitiation complex,biological_process
90177,GO:1901194,"Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.",negative regulation of formation of translation preinitiation complex,biological_process
90178,GO:1901195,"Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.",positive regulation of formation of translation preinitiation complex,biological_process
90179,GO:1901201,"Any process that modulates the frequency, rate or extent of extracellular matrix assembly.",regulation of extracellular matrix assembly,biological_process
90180,GO:1901202,"Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.",negative regulation of extracellular matrix assembly,biological_process
90181,GO:1901203,"Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.",positive regulation of extracellular matrix assembly,biological_process
90182,GO:1901207,"Any process that modulates the frequency, rate or extent of heart looping.",regulation of heart looping,biological_process
90183,GO:1901208,"Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.",negative regulation of heart looping,biological_process
90184,GO:1901209,"Any process that activates or increases the frequency, rate or extent of heart looping.",positive regulation of heart looping,biological_process
90185,GO:1901210,"Any process that modulates the frequency, rate or extent of cardiac chamber formation.",regulation of cardiac chamber formation,biological_process
90186,GO:1901211,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.",negative regulation of cardiac chamber formation,biological_process
90187,GO:1901212,"Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.",positive regulation of cardiac chamber formation,biological_process
90188,GO:1901219,"Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.",regulation of cardiac chamber morphogenesis,biological_process
90189,GO:1901220,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.",negative regulation of cardiac chamber morphogenesis,biological_process
90190,GO:1901221,"Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.",positive regulation of cardiac chamber morphogenesis,biological_process
90191,GO:1901222,"Any process that modulates the frequency, rate or extent of the non-canonical NF-kappaB signaling cascade.",regulation of non-canonical NF-kappaB signal transduction,biological_process
90192,GO:1901223,"Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical NF-kappaB signaling cascade.",negative regulation of non-canonical NF-kappaB signal transduction,biological_process
90193,GO:1901224,"Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade.",positive regulation of non-canonical NF-kappaB signal transduction,biological_process
90194,GO:1901232,"Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.",regulation of convergent extension involved in axis elongation,biological_process
90195,GO:1901235,Enables the transfer of (R)-carnitine from one side of a membrane to the other.,(R)-carnitine transmembrane transporter activity,molecular_function
90196,GO:1901236,Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other.,4-(trimethylammonio)butanoate transmembrane transporter activity,molecular_function
90197,GO:1901238,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).,ABC-type tungstate transporter activity,molecular_function
90198,GO:1901239,Enables the transfer of malonate(1-) from one side of a membrane to the other.,malonate(1-) transmembrane transporter activity,molecular_function
90199,GO:1901241,Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.,4-hydroxyphenylacetate transmembrane transporter activity,molecular_function
90200,GO:1901242,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).,ABC-type doxorubicin transporter activity,molecular_function
90201,GO:1901245,"The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling.",positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization,biological_process
90202,GO:1901246,"Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.",regulation of lung ciliated cell differentiation,biological_process
90203,GO:1901247,"Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.",negative regulation of lung ciliated cell differentiation,biological_process
90204,GO:1901248,"Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.",positive regulation of lung ciliated cell differentiation,biological_process
90205,GO:1901249,"Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.",regulation of lung goblet cell differentiation,biological_process
90206,GO:1901250,"Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.",negative regulation of lung goblet cell differentiation,biological_process
90207,GO:1901251,"Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.",positive regulation of lung goblet cell differentiation,biological_process
90208,GO:1901252,"Any process that modulates the frequency, rate or extent of egress of virus within host cell.",regulation of intracellular transport of viral material,biological_process
90209,GO:1901253,"Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.",negative regulation of intracellular transport of viral material,biological_process
90210,GO:1901254,"Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.",positive regulation of intracellular transport of viral material,biological_process
90211,GO:1901255,Any nucleotide-excision repair that is involved in interstrand cross-link repair.,nucleotide-excision repair involved in interstrand cross-link repair,biological_process
90212,GO:1901256,"Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.",regulation of macrophage colony-stimulating factor production,biological_process
90213,GO:1901257,"Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.",negative regulation of macrophage colony-stimulating factor production,biological_process
90214,GO:1901258,"Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.",positive regulation of macrophage colony-stimulating factor production,biological_process
90215,GO:1901259,Any rRNA processing that takes place in chloroplast.,chloroplast rRNA processing,biological_process
90216,GO:1901261,"Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.",regulation of sorocarp spore cell differentiation,biological_process
90217,GO:1901262,"Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.",negative regulation of sorocarp spore cell differentiation,biological_process
90218,GO:1901263,"Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.",positive regulation of sorocarp spore cell differentiation,biological_process
90219,GO:1901264,"The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",carbohydrate derivative transport,biological_process
90220,GO:1901265,Binding to nucleoside phosphate.,nucleoside phosphate binding,molecular_function
90221,GO:1901267,The chemical reactions and pathways resulting in the breakdown of cephalosporin C.,cephalosporin C catabolic process,biological_process
90222,GO:1901268,The chemical reactions and pathways resulting in the formation of cephalosporin C.,cephalosporin C biosynthetic process,biological_process
90223,GO:1901269,The chemical reactions and pathways involving lipooligosaccharide.,lipooligosaccharide metabolic process,biological_process
90224,GO:1901270,The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.,lipooligosaccharide catabolic process,biological_process
90225,GO:1901271,The chemical reactions and pathways resulting in the formation of lipooligosaccharide.,lipooligosaccharide biosynthetic process,biological_process
90226,GO:1901273,The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid.,2-dehydro-3-deoxy-D-gluconic acid catabolic process,biological_process
90227,GO:1901274,The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid.,2-dehydro-3-deoxy-D-gluconic acid biosynthetic process,biological_process
90228,GO:1901275,The chemical reactions and pathways involving tartrate.,tartrate metabolic process,biological_process
90229,GO:1901276,The chemical reactions and pathways resulting in the breakdown of tartrate.,tartrate catabolic process,biological_process
90230,GO:1901277,The chemical reactions and pathways resulting in the formation of tartrate.,tartrate biosynthetic process,biological_process
90231,GO:1901279,The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate.,D-ribose 5-phosphate catabolic process,biological_process
90232,GO:1901280,The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate.,D-ribose 5-phosphate biosynthetic process,biological_process
90233,GO:1901281,The chemical reactions and pathways resulting in the breakdown of fructoselysine.,fructoselysine catabolic process,biological_process
90234,GO:1901282,The chemical reactions and pathways resulting in the formation of fructoselysine.,fructoselysine biosynthetic process,biological_process
90235,GO:1901284,"The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin.","5,6,7,8-tetrahydromethanopterin catabolic process",biological_process
90236,GO:1901285,"The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin.","5,6,7,8-tetrahydromethanopterin biosynthetic process",biological_process
90237,GO:1901286,The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.,iron-sulfur-molybdenum cofactor metabolic process,biological_process
90238,GO:1901287,The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.,iron-sulfur-molybdenum cofactor catabolic process,biological_process
90239,GO:1901288,The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.,iron-sulfur-molybdenum cofactor biosynthetic process,biological_process
90240,GO:1901289,The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.,succinyl-CoA catabolic process,biological_process
90241,GO:1901290,The chemical reactions and pathways resulting in the formation of succinyl-CoA.,succinyl-CoA biosynthetic process,biological_process
90242,GO:1901291,"Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.",negative regulation of double-strand break repair via single-strand annealing,biological_process
90243,GO:1901292,The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.,nucleoside phosphate catabolic process,biological_process
90244,GO:1901293,The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.,nucleoside phosphate biosynthetic process,biological_process
90245,GO:1901298,"Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.",regulation of hydrogen peroxide-mediated programmed cell death,biological_process
90246,GO:1901299,"Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.",negative regulation of hydrogen peroxide-mediated programmed cell death,biological_process
90247,GO:1901300,"Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.",positive regulation of hydrogen peroxide-mediated programmed cell death,biological_process
90248,GO:1901301,"Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.",regulation of cargo loading into COPII-coated vesicle,biological_process
90249,GO:1901303,"Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.",negative regulation of cargo loading into COPII-coated vesicle,biological_process
90250,GO:1901304,"Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.",regulation of spermidine biosynthetic process,biological_process
90251,GO:1901305,"Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.",negative regulation of spermidine biosynthetic process,biological_process
90252,GO:1901307,"Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.",positive regulation of spermidine biosynthetic process,biological_process
90253,GO:1901317,"Any process that modulates the frequency, rate or extent of flagellated sperm motility.",regulation of flagellated sperm motility,biological_process
90254,GO:1901318,"Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.",negative regulation of flagellated sperm motility,biological_process
90255,GO:1901319,"Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.",positive regulation of trehalose catabolic process,biological_process
90256,GO:1901320,"Any process that stops, prevents or reduces the frequency, rate or extent of heart induction.",negative regulation of heart induction,biological_process
90257,GO:1901321,"Any process that activates or increases the frequency, rate or extent of heart induction.",positive regulation of heart induction,biological_process
90258,GO:1901322,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.",response to chloramphenicol,biological_process
90259,GO:1901323,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.",response to erythromycin,biological_process
90260,GO:1901324,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.",response to trichodermin,biological_process
90261,GO:1901325,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.",response to antimycin A,biological_process
90262,GO:1901326,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.",response to tetracycline,biological_process
90263,GO:1901327,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.",response to tacrolimus,biological_process
90264,GO:1901328,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.",response to cytochalasin B,biological_process
90265,GO:1901329,"Any process that modulates the frequency, rate or extent of odontoblast differentiation.",regulation of odontoblast differentiation,biological_process
90266,GO:1901330,"Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.",negative regulation of odontoblast differentiation,biological_process
90267,GO:1901331,"Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.",positive regulation of odontoblast differentiation,biological_process
90268,GO:1901332,"Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development.",negative regulation of lateral root development,biological_process
90269,GO:1901333,"Any process that activates or increases the frequency, rate or extent of lateral root development.",positive regulation of lateral root development,biological_process
90270,GO:1901334,The chemical reactions and pathways involving lactone.,lactone metabolic process,biological_process
90271,GO:1901335,The chemical reactions and pathways resulting in the breakdown of lactone.,lactone catabolic process,biological_process
90272,GO:1901336,The chemical reactions and pathways resulting in the formation of lactone.,lactone biosynthetic process,biological_process
90273,GO:1901337,"The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",thioester transport,biological_process
90274,GO:1901338,Binding to catecholamine.,catecholamine binding,molecular_function
90275,GO:1901339,"Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.",regulation of store-operated calcium channel activity,biological_process
90276,GO:1901340,"Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.",negative regulation of store-operated calcium channel activity,biological_process
90277,GO:1901341,"Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.",positive regulation of store-operated calcium channel activity,biological_process
90278,GO:1901342,"Any process that modulates the frequency, rate or extent of vasculature development.",regulation of vasculature development,biological_process
90279,GO:1901343,"Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.",negative regulation of vasculature development,biological_process
90280,GO:1901344,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.",response to leptomycin B,biological_process
90281,GO:1901345,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.",response to L-thialysine,biological_process
90282,GO:1901346,Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.,negative regulation of vasculature development involved in avascular cornea development in camera-type eye,biological_process
90283,GO:1901347,"Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.",negative regulation of secondary cell wall biogenesis,biological_process
90284,GO:1901348,"Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.",positive regulation of secondary cell wall biogenesis,biological_process
90285,GO:1901349,"The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glucosinolate transport,biological_process
90286,GO:1901351,"Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.",regulation of phosphatidylglycerol biosynthetic process,biological_process
90287,GO:1901352,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.",negative regulation of phosphatidylglycerol biosynthetic process,biological_process
90288,GO:1901353,"Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.",positive regulation of phosphatidylglycerol biosynthetic process,biological_process
90289,GO:1901354,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.",response to L-canavanine,biological_process
90290,GO:1901355,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.",response to rapamycin,biological_process
90291,GO:1901357,The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.,beta-D-galactofuranose catabolic process,biological_process
90292,GO:1901358,The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose.,beta-D-galactofuranose biosynthetic process,biological_process
90293,GO:1901359,Binding to tungstate.,tungstate binding,molecular_function
90294,GO:1901363,Binding to heterocyclic compound.,heterocyclic compound binding,molecular_function
90295,GO:1901365,The chemical reactions and pathways resulting in the breakdown of funalenone.,funalenone catabolic process,biological_process
90296,GO:1901366,The chemical reactions and pathways resulting in the formation of funalenone.,funalenone biosynthetic process,biological_process
90297,GO:1901367,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.",response to L-cysteine,biological_process
90298,GO:1901369,"The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid.","cyclic 2,3-bisphospho-D-glycerate biosynthetic process",biological_process
90299,GO:1901370,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.",response to glutathione,biological_process
90300,GO:1901371,"Any process that modulates the frequency, rate or extent of leaf morphogenesis.",regulation of leaf morphogenesis,biological_process
90301,GO:1901373,"The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",lipid hydroperoxide transport,biological_process
90302,GO:1901374,"The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",acetate ester transport,biological_process
90303,GO:1901375,Enables the transfer of an acetate ester from one side of a membrane to the other.,acetate ester transmembrane transporter activity,molecular_function
90304,GO:1901379,"Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.",regulation of potassium ion transmembrane transport,biological_process
90305,GO:1901380,"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.",negative regulation of potassium ion transmembrane transport,biological_process
90306,GO:1901381,"Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.",positive regulation of potassium ion transmembrane transport,biological_process
90307,GO:1901382,"Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.",regulation of chorionic trophoblast cell proliferation,biological_process
90308,GO:1901383,"Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.",negative regulation of chorionic trophoblast cell proliferation,biological_process
90309,GO:1901384,"Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.",positive regulation of chorionic trophoblast cell proliferation,biological_process
90310,GO:1901385,"Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.",regulation of voltage-gated calcium channel activity,biological_process
90311,GO:1901386,"Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.",negative regulation of voltage-gated calcium channel activity,biological_process
90312,GO:1901387,"Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.",positive regulation of voltage-gated calcium channel activity,biological_process
90313,GO:1901401,"Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.",regulation of tetrapyrrole metabolic process,biological_process
90314,GO:1901404,"Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.",regulation of tetrapyrrole catabolic process,biological_process
90315,GO:1901405,"Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.",negative regulation of tetrapyrrole catabolic process,biological_process
90316,GO:1901406,"Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.",positive regulation of tetrapyrrole catabolic process,biological_process
90317,GO:1901416,"Any process that modulates the frequency, rate or extent of response to ethanol.",regulation of response to ethanol,biological_process
90318,GO:1901417,"Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol.",negative regulation of response to ethanol,biological_process
90319,GO:1901418,"Any process that activates or increases the frequency, rate or extent of response to ethanol.",positive regulation of response to ethanol,biological_process
90320,GO:1901419,"Any process that modulates the frequency, rate or extent of response to alcohol.",regulation of response to alcohol,biological_process
90321,GO:1901420,"Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.",negative regulation of response to alcohol,biological_process
90322,GO:1901421,"Any process that activates or increases the frequency, rate or extent of response to alcohol.",positive regulation of response to alcohol,biological_process
90323,GO:1901422,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.",response to butan-1-ol,biological_process
90324,GO:1901423,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.",response to benzene,biological_process
90325,GO:1901424,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus.",response to toluene,biological_process
90326,GO:1901425,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.",response to formic acid,biological_process
90327,GO:1901426,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus.",response to furfural,biological_process
90328,GO:1901427,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.",response to propan-1-ol,biological_process
90329,GO:1901428,"Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.",regulation of syringal lignin biosynthetic process,biological_process
90330,GO:1901429,"Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.",negative regulation of syringal lignin biosynthetic process,biological_process
90331,GO:1901430,"Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process.",positive regulation of syringal lignin biosynthetic process,biological_process
90332,GO:1901431,"Any process that modulates the frequency, rate or extent of response to cycloalkane.",regulation of response to cycloalkane,biological_process
90333,GO:1901432,"Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane.",negative regulation of response to cycloalkane,biological_process
90334,GO:1901433,"Any process that activates or increases the frequency, rate or extent of response to cycloalkane.",positive regulation of response to cycloalkane,biological_process
90335,GO:1901434,"Any process that modulates the frequency, rate or extent of toluene catabolic process.",regulation of toluene catabolic process,biological_process
90336,GO:1901435,"Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.",negative regulation of toluene catabolic process,biological_process
90337,GO:1901436,"Any process that activates or increases the frequency, rate or extent of toluene catabolic process.",positive regulation of toluene catabolic process,biological_process
90338,GO:1901441,The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).,poly(hydroxyalkanoate) biosynthetic process,biological_process
90339,GO:1901442,"Any process that modulates the frequency, rate or extent of response to furfural.",regulation of response to furfural,biological_process
90340,GO:1901443,"Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural.",negative regulation of response to furfural,biological_process
90341,GO:1901444,"Any process that activates or increases the frequency, rate or extent of response to furfural.",positive regulation of response to furfural,biological_process
90342,GO:1901445,"Any process that modulates the frequency, rate or extent of response to propan-1-ol.",regulation of response to propan-1-ol,biological_process
90343,GO:1901446,"Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.",negative regulation of response to propan-1-ol,biological_process
90344,GO:1901447,"Any process that activates or increases the frequency, rate or extent of response to propan-1-ol.",positive regulation of response to propan-1-ol,biological_process
90345,GO:1901448,"Any process that modulates the frequency, rate or extent of response to butan-1-ol.",regulation of response to butan-1-ol,biological_process
90346,GO:1901449,"Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol.",negative regulation of response to butan-1-ol,biological_process
90347,GO:1901450,"Any process that activates or increases the frequency, rate or extent of response to butan-1-ol.",positive regulation of response to butan-1-ol,biological_process
90348,GO:1901451,"Any process that modulates the frequency, rate or extent of response to benzene.",regulation of response to benzene,biological_process
90349,GO:1901452,"Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.",negative regulation of response to benzene,biological_process
90350,GO:1901453,"Any process that activates or increases the frequency, rate or extent of response to benzene.",positive regulation of response to benzene,biological_process
90351,GO:1901454,"Any process that modulates the frequency, rate or extent of response to toluene.",regulation of response to toluene,biological_process
90352,GO:1901455,"Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene.",negative regulation of response to toluene,biological_process
90353,GO:1901456,"Any process that activates or increases the frequency, rate or extent of response to toluene.",positive regulation of response to toluene,biological_process
90354,GO:1901457,"Any process that modulates the frequency, rate or extent of response to acetate.",regulation of response to acetate,biological_process
90355,GO:1901458,"Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.",negative regulation of response to acetate,biological_process
90356,GO:1901459,"Any process that activates or increases the frequency, rate or extent of response to acetate.",positive regulation of response to acetate,biological_process
90357,GO:1901460,"Any process that modulates the frequency, rate or extent of response to formic acid.",regulation of response to formic acid,biological_process
90358,GO:1901461,"Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.",negative regulation of response to formic acid,biological_process
90359,GO:1901462,"Any process that activates or increases the frequency, rate or extent of response to formic acid.",positive regulation of response to formic acid,biological_process
90360,GO:1901463,"Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.",regulation of tetrapyrrole biosynthetic process,biological_process
90361,GO:1901464,"Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.",negative regulation of tetrapyrrole biosynthetic process,biological_process
90362,GO:1901465,"Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.",positive regulation of tetrapyrrole biosynthetic process,biological_process
90363,GO:1901466,"Any process that modulates the frequency, rate or extent of ferulate catabolic process.",regulation of ferulate catabolic process,biological_process
90364,GO:1901467,"Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process.",negative regulation of ferulate catabolic process,biological_process
90365,GO:1901468,"Any process that activates or increases the frequency, rate or extent of ferulate catabolic process.",positive regulation of ferulate catabolic process,biological_process
90366,GO:1901469,"Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.",regulation of syringal lignin catabolic process,biological_process
90367,GO:1901470,"Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.",negative regulation of syringal lignin catabolic process,biological_process
90368,GO:1901471,"Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.",positive regulation of syringal lignin catabolic process,biological_process
90369,GO:1901472,"Any process that modulates the frequency, rate or extent of Golgi calcium ion export.",regulation of Golgi calcium ion export,biological_process
90370,GO:1901474,"Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.",azole transmembrane transporter activity,molecular_function
90371,GO:1901475,The directed movement of pyruvate across a membrane.,pyruvate transmembrane transport,biological_process
90372,GO:1901478,Enables the transfer of amitrole from one side of a membrane to the other.,aminotriazole transmembrane transporter activity,molecular_function
90373,GO:1901480,Enables the transfer of oleate from one side of a membrane to the other.,oleate transmembrane transporter activity,molecular_function
90374,GO:1901490,"Any process that modulates the frequency, rate or extent of lymphangiogenesis.",regulation of lymphangiogenesis,biological_process
90375,GO:1901491,"Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.",negative regulation of lymphangiogenesis,biological_process
90376,GO:1901492,"Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.",positive regulation of lymphangiogenesis,biological_process
90377,GO:1901493,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.",response to decalin,biological_process
90378,GO:1901497,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus.",response to diphenyl ether,biological_process
90379,GO:1901498,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus.",response to tetralin,biological_process
90380,GO:1901499,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus.",response to hexane,biological_process
90381,GO:1901500,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.",response to p-xylene,biological_process
90382,GO:1901501,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus.",response to xylene,biological_process
90383,GO:1901502,The chemical reactions and pathways resulting in the breakdown of ether.,ether catabolic process,biological_process
90384,GO:1901503,The chemical reactions and pathways resulting in the formation of ether.,ether biosynthetic process,biological_process
90385,GO:1901504,"The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",triazole transport,biological_process
90386,GO:1901505,Enables the transfer of carbohydrate derivative from one side of a membrane to the other.,carbohydrate derivative transmembrane transporter activity,molecular_function
90387,GO:1901506,"Any process that modulates the frequency, rate or extent of acylglycerol transport.",regulation of acylglycerol transport,biological_process
90388,GO:1901507,"Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.",negative regulation of acylglycerol transport,biological_process
90389,GO:1901508,"Any process that activates or increases the frequency, rate or extent of acylglycerol transport.",positive regulation of acylglycerol transport,biological_process
90390,GO:1901509,"Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.",regulation of endothelial tube morphogenesis,biological_process
90391,GO:1901511,The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone.,(-)-microperfuranone catabolic process,biological_process
90392,GO:1901512,The chemical reactions and pathways resulting in the formation of (-)-microperfuranone.,(-)-microperfuranone biosynthetic process,biological_process
90393,GO:1901513,Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.,lipo-chitin oligosaccharide transmembrane transporter activity,molecular_function
90394,GO:1901514,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out).,ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity,molecular_function
90395,GO:1901515,"Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other.","poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity",molecular_function
90396,GO:1901517,The chemical reactions and pathways resulting in the breakdown of aspyridone A.,aspyridone A catabolic process,biological_process
90397,GO:1901518,The chemical reactions and pathways resulting in the formation of aspyridone A.,aspyridone A biosynthetic process,biological_process
90398,GO:1901520,The chemical reactions and pathways resulting in the breakdown of aspyridone B.,aspyridone B catabolic process,biological_process
90399,GO:1901521,The chemical reactions and pathways resulting in the formation of aspyridone B.,aspyridone B biosynthetic process,biological_process
90400,GO:1901523,The chemical reactions and pathways resulting in the breakdown of icosanoid.,icosanoid catabolic process,biological_process
90401,GO:1901524,"Any process that modulates the frequency, rate or extent of macromitophagy.",regulation of mitophagy,biological_process
90402,GO:1901525,"Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy.",negative regulation of mitophagy,biological_process
90403,GO:1901526,"Any process that activates or increases the frequency, rate or extent of mitophagy.",positive regulation of mitophagy,biological_process
90404,GO:1901527,Any abscisic acid mediated signaling pathway that is involved in stomatal movement.,abscisic acid-activated signaling pathway involved in stomatal movement,biological_process
90405,GO:1901529,"Any process that activates or increases the frequency, rate or extent of anion channel activity.",positive regulation of anion channel activity,biological_process
90406,GO:1901530,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.",response to hypochlorite,biological_process
90407,GO:1901531,Binding to hypochlorite.,hypochlorite binding,molecular_function
90408,GO:1901532,"Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.",regulation of hematopoietic progenitor cell differentiation,biological_process
90409,GO:1901533,"Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.",negative regulation of hematopoietic progenitor cell differentiation,biological_process
90410,GO:1901534,"Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.",positive regulation of hematopoietic progenitor cell differentiation,biological_process
90411,GO:1901540,"The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene.","ent-pimara-8(14),15-diene catabolic process",biological_process
90412,GO:1901541,"The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene.","ent-pimara-8(14),15-diene biosynthetic process",biological_process
90413,GO:1901542,"Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.","regulation of ent-pimara-8(14),15-diene biosynthetic process",biological_process
90414,GO:1901543,"Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.","negative regulation of ent-pimara-8(14),15-diene biosynthetic process",biological_process
90415,GO:1901544,"Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.","positive regulation of ent-pimara-8(14),15-diene biosynthetic process",biological_process
90416,GO:1901545,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.",response to raffinose,biological_process
90417,GO:1901546,"Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.",regulation of synaptic vesicle lumen acidification,biological_process
90418,GO:1901547,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification.",negative regulation of synaptic vesicle lumen acidification,biological_process
90419,GO:1901548,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.",positive regulation of synaptic vesicle lumen acidification,biological_process
90420,GO:1901550,"Any process that modulates the frequency, rate or extent of endothelial cell development.",regulation of endothelial cell development,biological_process
90421,GO:1901551,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.",negative regulation of endothelial cell development,biological_process
90422,GO:1901552,"Any process that activates or increases the frequency, rate or extent of endothelial cell development.",positive regulation of endothelial cell development,biological_process
90423,GO:1901553,The directed movement of malonic acid across a membrane.,malonic acid transmembrane transport,biological_process
90424,GO:1901554,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.",response to paracetamol,biological_process
90425,GO:1901556,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.",response to candesartan,biological_process
90426,GO:1901557,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.",response to fenofibrate,biological_process
90427,GO:1901558,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.",response to metformin,biological_process
90428,GO:1901559,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.",response to ribavirin,biological_process
90429,GO:1901560,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.",response to purvalanol A,biological_process
90430,GO:1901562,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.",response to paraquat,biological_process
90431,GO:1901563,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.",response to camptothecin,biological_process
90432,GO:1901567,Binding to fatty acid derivative.,fatty acid derivative binding,molecular_function
90433,GO:1901568,The chemical reactions and pathways involving fatty acid derivative.,fatty acid derivative metabolic process,biological_process
90434,GO:1901569,The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.,fatty acid derivative catabolic process,biological_process
90435,GO:1901570,The chemical reactions and pathways resulting in the formation of fatty acid derivative.,fatty acid derivative biosynthetic process,biological_process
90436,GO:1901571,"The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",fatty acid derivative transport,biological_process
90437,GO:1901577,"Any process that modulates the frequency, rate or extent of alkane biosynthetic process.",regulation of alkane biosynthetic process,biological_process
90438,GO:1901578,"Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.",negative regulation of alkane biosynthetic process,biological_process
90439,GO:1901579,"Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.",positive regulation of alkane biosynthetic process,biological_process
90440,GO:1901583,"The directed movement of a tetrapeptide from outside of a cell, across the plasma membrane and into the cytosol.",tetrapeptide import across plasma membrane,biological_process
90441,GO:1901584,Enables the transfer of tetrapeptide from one side of a membrane to the other.,tetrapeptide transmembrane transporter activity,molecular_function
90442,GO:1901588,"Any microtubule in a dendrite, a neuron projection.",dendritic microtubule,cellular_component
90443,GO:1901589,An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.,axon microtubule bundle,cellular_component
90444,GO:1901591,"Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.",regulation of double-strand break repair via break-induced replication,biological_process
90445,GO:1901592,"Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.",negative regulation of double-strand break repair via break-induced replication,biological_process
90446,GO:1901593,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.",response to GW 7647,biological_process
90447,GO:1901594,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.",response to capsazepine,biological_process
90448,GO:1901595,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.",response to hesperadin,biological_process
90449,GO:1901596,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.",response to reversine,biological_process
90450,GO:1901597,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.",response to carbendazim,biological_process
90451,GO:1901598,The chemical reactions and pathways involving (-)-pinoresinol.,(-)-pinoresinol metabolic process,biological_process
90452,GO:1901599,The chemical reactions and pathways resulting in the formation of (-)-pinoresinol.,(-)-pinoresinol biosynthetic process,biological_process
90453,GO:1901600,The chemical reactions and pathways involving strigolactone.,strigolactone metabolic process,biological_process
90454,GO:1901601,The chemical reactions and pathways resulting in the formation of strigolactone.,strigolactone biosynthetic process,biological_process
90455,GO:1901602,Binding to dethiobiotin.,dethiobiotin binding,molecular_function
90456,GO:1901604,Enables the transfer of dethiobiotin from one side of a membrane to the other.,dethiobiotin transmembrane transporter activity,molecular_function
90457,GO:1901608,"Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.",regulation of vesicle transport along microtubule,biological_process
90458,GO:1901609,"Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.",negative regulation of vesicle transport along microtubule,biological_process
90459,GO:1901610,"Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.",positive regulation of vesicle transport along microtubule,biological_process
90460,GO:1901611,Binding to phosphatidylglycerol.,phosphatidylglycerol binding,molecular_function
90461,GO:1901612,Binding to cardiolipin.,cardiolipin binding,molecular_function
90462,GO:1901613,"Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization.",negative regulation of terminal button organization,biological_process
90463,GO:1901614,"Any process that activates or increases the frequency, rate or extent of terminal button organization.",positive regulation of terminal button organization,biological_process
90464,GO:1901620,"Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.",regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning,biological_process
90465,GO:1901621,"Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.",negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning,biological_process
90466,GO:1901623,"Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.",regulation of lymphocyte chemotaxis,biological_process
90467,GO:1901624,"Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.",negative regulation of lymphocyte chemotaxis,biological_process
90468,GO:1901625,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.",cellular response to ergosterol,biological_process
90469,GO:1901626,"Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.",regulation of postsynaptic membrane organization,biological_process
90470,GO:1901627,"Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.",negative regulation of postsynaptic membrane organization,biological_process
90471,GO:1901628,"Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.",positive regulation of postsynaptic membrane organization,biological_process
90472,GO:1901629,"Any process that modulates the frequency, rate or extent of presynaptic membrane organization.",regulation of presynaptic membrane organization,biological_process
90473,GO:1901630,"Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.",negative regulation of presynaptic membrane organization,biological_process
90474,GO:1901631,"Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization.",positive regulation of presynaptic membrane organization,biological_process
90475,GO:1901632,"Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.",regulation of synaptic vesicle membrane organization,biological_process
90476,GO:1901633,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.",negative regulation of synaptic vesicle membrane organization,biological_process
90477,GO:1901634,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization.",positive regulation of synaptic vesicle membrane organization,biological_process
90478,GO:1901640,Binding to XTP.,XTP binding,molecular_function
90479,GO:1901641,Binding to ITP.,ITP binding,molecular_function
90480,GO:1901642,The directed movement of nucleoside across a membrane.,nucleoside transmembrane transport,biological_process
90481,GO:1901645,"Any process that modulates the frequency, rate or extent of synoviocyte proliferation.",regulation of synoviocyte proliferation,biological_process
90482,GO:1901646,"Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.",negative regulation of synoviocyte proliferation,biological_process
90483,GO:1901647,"Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.",positive regulation of synoviocyte proliferation,biological_process
90484,GO:1901652,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.",response to peptide,biological_process
90485,GO:1901653,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.",cellular response to peptide,biological_process
90486,GO:1901654,A response that results in a state of tolerance to ketone.,response to ketone,biological_process
90487,GO:1901655,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.",cellular response to ketone,biological_process
90488,GO:1901656,"The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",glycoside transport,biological_process
90489,GO:1901658,The chemical reactions and pathways resulting in the breakdown of glycosyl compound.,glycosyl compound catabolic process,biological_process
90490,GO:1901659,The chemical reactions and pathways resulting in the formation of glycosyl compound.,glycosyl compound biosynthetic process,biological_process
90491,GO:1901660,The directed movement of calcium ion out of a cell or organelle.,calcium ion export,biological_process
90492,GO:1901661,The chemical reactions and pathways involving quinone.,quinone metabolic process,biological_process
90493,GO:1901662,The chemical reactions and pathways resulting in the breakdown of quinone.,quinone catabolic process,biological_process
90494,GO:1901663,The chemical reactions and pathways resulting in the formation of quinone.,quinone biosynthetic process,biological_process
90495,GO:1901668,"Any process that modulates the frequency, rate or extent of superoxide dismutase activity.",regulation of superoxide dismutase activity,biological_process
90496,GO:1901671,"Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.",positive regulation of superoxide dismutase activity,biological_process
90497,GO:1901672,"Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.",positive regulation of systemic acquired resistance,biological_process
90498,GO:1901673,"Any process that modulates the frequency, rate or extent of mitotic spindle assembly.",regulation of mitotic spindle assembly,biological_process
90499,GO:1901678,"The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",iron coordination entity transport,biological_process
90500,GO:1901679,The directed movement of nucleotide across a membrane.,nucleotide transmembrane transport,biological_process
90501,GO:1901681,Binding to a sulfur compound.,sulfur compound binding,molecular_function
90502,GO:1901682,Enables the transfer of a sulfur compound from one side of a membrane to the other.,sulfur compound transmembrane transporter activity,molecular_function
90503,GO:1901683,Enables the transfer of an arsenate ion from one side of a membrane to the other.,arsenate ion transmembrane transporter activity,molecular_function
90504,GO:1901684,The process in which arsenate is transported across a membrane.,arsenate ion transmembrane transport,biological_process
90505,GO:1901686,The chemical reactions and pathways resulting in the breakdown of glutathione derivative.,glutathione derivative catabolic process,biological_process
90506,GO:1901687,The chemical reactions and pathways resulting in the formation of glutathione derivative.,glutathione derivative biosynthetic process,biological_process
90507,GO:1901691,Binding to proton.,proton binding,molecular_function
90508,GO:1901692,"Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.",regulation of compound eye retinal cell apoptotic process,biological_process
90509,GO:1901693,"Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.",negative regulation of compound eye retinal cell apoptotic process,biological_process
90510,GO:1901694,"Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.",positive regulation of compound eye retinal cell apoptotic process,biological_process
90511,GO:1901695,The chemical reactions and pathways resulting in the formation of tyramine.,tyramine biosynthetic process,biological_process
90512,GO:1901696,The chemical reactions and pathways resulting in the formation of cannabinoid.,cannabinoid biosynthetic process,biological_process
90513,GO:1901697,The chemical reactions and pathways resulting in the formation of olivetolic acid.,olivetolic acid biosynthetic process,biological_process
90514,GO:1901698,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.",response to nitrogen compound,biological_process
90515,GO:1901699,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.",cellular response to nitrogen compound,biological_process
90516,GO:1901700,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.",response to oxygen-containing compound,biological_process
90517,GO:1901701,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.",cellular response to oxygen-containing compound,biological_process
90518,GO:1901702,Enables the transfer of salt from one side of a membrane to the other.,salt transmembrane transporter activity,molecular_function
90519,GO:1901703,Any protein localization that is involved in auxin polar transport.,protein localization involved in auxin polar transport,biological_process
90520,GO:1901704,The chemical reactions and pathways resulting in the formation of L-glutamine.,L-glutamine biosynthetic process,biological_process
90521,GO:1901705,The chemical reactions and pathways resulting in the formation of L-isoleucine.,L-isoleucine biosynthetic process,biological_process
90522,GO:1901706,The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.,mesenchymal cell differentiation involved in bone development,biological_process
90523,GO:1901707,Binding to leptomycin B.,leptomycin B binding,molecular_function
90524,GO:1901708,The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin.,(+)-3'-hydroxylarreatricin biosynthetic process,biological_process
90525,GO:1901709,The chemical reactions and pathways resulting in the formation of (+)-larreatricin.,(+)-larreatricin biosynthetic process,biological_process
90526,GO:1901710,"Any process that modulates the frequency, rate or extent of homoserine biosynthetic process.",regulation of homoserine biosynthetic process,biological_process
90527,GO:1901711,"Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process.",negative regulation of homoserine biosynthetic process,biological_process
90528,GO:1901712,"Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process.",positive regulation of homoserine biosynthetic process,biological_process
90529,GO:1901713,"Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process.",negative regulation of urea catabolic process,biological_process
90530,GO:1901714,"Any process that activates or increases the frequency, rate or extent of urea catabolic process.",positive regulation of urea catabolic process,biological_process
90531,GO:1901715,"Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.",regulation of GABA catabolic process,biological_process
90532,GO:1901716,"Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.",negative regulation of GABA catabolic process,biological_process
90533,GO:1901717,"Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.",positive regulation of GABA catabolic process,biological_process
90534,GO:1901723,"Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.",negative regulation of cell proliferation involved in kidney development,biological_process
90535,GO:1901724,"Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.",positive regulation of cell proliferation involved in kidney development,biological_process
90536,GO:1901729,The chemical reactions and pathways resulting in the breakdown of monensin A.,monensin A catabolic process,biological_process
90537,GO:1901730,The chemical reactions and pathways resulting in the formation of monensin A.,monensin A biosynthetic process,biological_process
90538,GO:1901731,"Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.",positive regulation of platelet aggregation,biological_process
90539,GO:1901733,The chemical reactions and pathways resulting in the breakdown of quercetin.,quercetin catabolic process,biological_process
90540,GO:1901734,The chemical reactions and pathways resulting in the formation of quercetin.,quercetin biosynthetic process,biological_process
90541,GO:1901736,The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid.,(R)-mevalonic acid catabolic process,biological_process
90542,GO:1901737,The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid.,(R)-mevalonic acid biosynthetic process,biological_process
90543,GO:1901738,"Any process that modulates the frequency, rate or extent of vitamin A metabolic process.",regulation of vitamin A metabolic process,biological_process
90544,GO:1901739,"Any process that modulates the frequency, rate or extent of myoblast fusion.",regulation of myoblast fusion,biological_process
90545,GO:1901740,"Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.",negative regulation of myoblast fusion,biological_process
90546,GO:1901741,"Any process that activates or increases the frequency, rate or extent of myoblast fusion.",positive regulation of myoblast fusion,biological_process
90547,GO:1901742,The chemical reactions and pathways involving 2-deoxystreptamine.,2-deoxystreptamine metabolic process,biological_process
90548,GO:1901743,The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine.,2-deoxystreptamine catabolic process,biological_process
90549,GO:1901744,The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.,2-deoxystreptamine biosynthetic process,biological_process
90550,GO:1901746,The chemical reactions and pathways resulting in the breakdown of prephenate(2-).,prephenate(2-) catabolic process,biological_process
90551,GO:1901747,The chemical reactions and pathways resulting in the formation of prephenate(2-).,prephenate(2-) biosynthetic process,biological_process
90552,GO:1901749,The chemical reactions and pathways resulting in the breakdown of leukotriene D4.,leukotriene D4 catabolic process,biological_process
90553,GO:1901750,The chemical reactions and pathways resulting in the formation of leukotriene D4.,leukotriene D4 biosynthetic process,biological_process
90554,GO:1901751,The chemical reactions and pathways involving leukotriene A4.,leukotriene A4 metabolic process,biological_process
90555,GO:1901752,The chemical reactions and pathways resulting in the breakdown of leukotriene A4.,leukotriene A4 catabolic process,biological_process
90556,GO:1901753,The chemical reactions and pathways resulting in the formation of leukotriene A4.,leukotriene A4 biosynthetic process,biological_process
90557,GO:1901754,The chemical reactions and pathways resulting in the breakdown of vitamin D3.,vitamin D3 catabolic process,biological_process
90558,GO:1901755,The chemical reactions and pathways resulting in the formation of vitamin D3.,vitamin D3 biosynthetic process,biological_process
90559,GO:1901757,The chemical reactions and pathways resulting in the breakdown of butirosin.,butirosin catabolic process,biological_process
90560,GO:1901758,The chemical reactions and pathways resulting in the formation of butirosin.,butirosin biosynthetic process,biological_process
90561,GO:1901760,The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.,beta-L-Ara4N-lipid A biosynthetic process,biological_process
90562,GO:1901762,The chemical reactions and pathways resulting in the breakdown of oxytetracycline.,oxytetracycline catabolic process,biological_process
90563,GO:1901763,The chemical reactions and pathways resulting in the formation of oxytetracycline.,oxytetracycline biosynthetic process,biological_process
90564,GO:1901766,The chemical reactions and pathways resulting in the formation of phosphinothricin.,L-phosphinothricin biosynthetic process,biological_process
90565,GO:1901768,The chemical reactions and pathways resulting in the breakdown of carbapenem.,carbapenem catabolic process,biological_process
90566,GO:1901769,The chemical reactions and pathways resulting in the formation of carbapenem.,carbapenem biosynthetic process,biological_process
90567,GO:1901770,The chemical reactions and pathways resulting in the breakdown of daunorubicin.,daunorubicin catabolic process,biological_process
90568,GO:1901771,The chemical reactions and pathways resulting in the formation of daunorubicin.,daunorubicin biosynthetic process,biological_process
90569,GO:1901773,The chemical reactions and pathways resulting in the breakdown of lincomycin.,lincomycin catabolic process,biological_process
90570,GO:1901774,The chemical reactions and pathways resulting in the formation of lincomycin.,lincomycin biosynthetic process,biological_process
90571,GO:1901776,The chemical reactions and pathways resulting in the breakdown of mitomycin C.,mitomycin C catabolic process,biological_process
90572,GO:1901777,The chemical reactions and pathways resulting in the formation of mitomycin C.,mitomycin C biosynthetic process,biological_process
90573,GO:1901779,The chemical reactions and pathways resulting in the breakdown of pentalenolactone.,pentalenolactone catabolic process,biological_process
90574,GO:1901780,The chemical reactions and pathways resulting in the formation of pentalenolactone.,pentalenolactone biosynthetic process,biological_process
90575,GO:1901782,The chemical reactions and pathways resulting in the breakdown of p-cumate.,p-cumate catabolic process,biological_process
90576,GO:1901783,The chemical reactions and pathways resulting in the formation of p-cumate.,p-cumate biosynthetic process,biological_process
90577,GO:1901785,The chemical reactions and pathways resulting in the breakdown of p-cresol.,p-cresol catabolic process,biological_process
90578,GO:1901786,The chemical reactions and pathways resulting in the formation of p-cresol.,p-cresol biosynthetic process,biological_process
90579,GO:1901787,The chemical reactions and pathways involving benzoyl-CoA.,benzoyl-CoA metabolic process,biological_process
90580,GO:1901788,The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA.,benzoyl-CoA catabolic process,biological_process
90581,GO:1901789,The chemical reactions and pathways resulting in the formation of benzoyl-CoA.,benzoyl-CoA biosynthetic process,biological_process
90582,GO:1901792,"The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate.","3-(2,3-dihydroxyphenyl)propanoate biosynthetic process",biological_process
90583,GO:1901794,The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate.,3-(3-hydroxyphenyl)propanoate catabolic process,biological_process
90584,GO:1901795,The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate.,3-(3-hydroxyphenyl)propanoate biosynthetic process,biological_process
90585,GO:1901796,"Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.",regulation of signal transduction by p53 class mediator,biological_process
90586,GO:1901797,"Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.",negative regulation of signal transduction by p53 class mediator,biological_process
90587,GO:1901798,"Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.",positive regulation of signal transduction by p53 class mediator,biological_process
90588,GO:1901799,"Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.",negative regulation of proteasomal protein catabolic process,biological_process
90589,GO:1901800,"Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.",positive regulation of proteasomal protein catabolic process,biological_process
90590,GO:1901802,"The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.","1,5-anhydro-D-fructose catabolic process",biological_process
90591,GO:1901805,The chemical reactions and pathways resulting in the breakdown of beta-glucoside.,beta-glucoside catabolic process,biological_process
90592,GO:1901806,The chemical reactions and pathways resulting in the formation of beta-glucoside.,beta-glucoside biosynthetic process,biological_process
90593,GO:1901808,The chemical reactions and pathways resulting in the breakdown of capsanthin.,capsanthin catabolic process,biological_process
90594,GO:1901809,The chemical reactions and pathways resulting in the formation of capsanthin.,capsanthin biosynthetic process,biological_process
90595,GO:1901810,The chemical reactions and pathways involving beta-carotene.,beta-carotene metabolic process,biological_process
90596,GO:1901811,The chemical reactions and pathways resulting in the breakdown of beta-carotene.,beta-carotene catabolic process,biological_process
90597,GO:1901812,The chemical reactions and pathways resulting in the formation of beta-carotene.,beta-carotene biosynthetic process,biological_process
90598,GO:1901815,The chemical reactions and pathways resulting in the formation of astaxanthin.,astaxanthin biosynthetic process,biological_process
90599,GO:1901817,The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.,beta-zeacarotene catabolic process,biological_process
90600,GO:1901818,The chemical reactions and pathways resulting in the formation of beta-zeacarotene.,beta-zeacarotene biosynthetic process,biological_process
90601,GO:1901820,The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.,alpha-zeacarotene catabolic process,biological_process
90602,GO:1901821,The chemical reactions and pathways resulting in the formation of alpha-zeacarotene.,alpha-zeacarotene biosynthetic process,biological_process
90603,GO:1901824,The chemical reactions and pathways resulting in the formation of alpha-carotene.,alpha-carotene biosynthetic process,biological_process
90604,GO:1901826,The chemical reactions and pathways resulting in the breakdown of zeaxanthin.,zeaxanthin catabolic process,biological_process
90605,GO:1901827,The chemical reactions and pathways resulting in the formation of zeaxanthin.,zeaxanthin biosynthetic process,biological_process
90606,GO:1901830,The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside).,zeaxanthin bis(beta-D-glucoside) biosynthetic process,biological_process
90607,GO:1901833,The chemical reactions and pathways resulting in the formation of trans-neoxanthin and 9'-cis-neoxanthin.,neoxanthin biosynthetic process,biological_process
90608,GO:1901834,"Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.",regulation of deadenylation-independent decapping of nuclear-transcribed mRNA,biological_process
90609,GO:1901835,"Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.",positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA,biological_process
90610,GO:1901836,"Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.",regulation of transcription of nucleolar large rRNA by RNA polymerase I,biological_process
90611,GO:1901837,"Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.",negative regulation of transcription of nucleolar large rRNA by RNA polymerase I,biological_process
90612,GO:1901838,"Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.",positive regulation of transcription of nucleolar large rRNA by RNA polymerase I,biological_process
90613,GO:1901842,"Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.",negative regulation of high voltage-gated calcium channel activity,biological_process
90614,GO:1901843,"Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.",positive regulation of high voltage-gated calcium channel activity,biological_process
90615,GO:1901844,"Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.",regulation of cell communication by electrical coupling involved in cardiac conduction,biological_process
90616,GO:1901845,"Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.",negative regulation of cell communication by electrical coupling involved in cardiac conduction,biological_process
90617,GO:1901846,"Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.",positive regulation of cell communication by electrical coupling involved in cardiac conduction,biological_process
90618,GO:1901847,The chemical reactions and pathways involving nicotinate.,nicotinate metabolic process,biological_process
90619,GO:1901848,The chemical reactions and pathways resulting in the breakdown of nicotinate.,nicotinate catabolic process,biological_process
90620,GO:1901849,The chemical reactions and pathways resulting in the formation of nicotinate.,nicotinate biosynthetic process,biological_process
90621,GO:1901851,"The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.","7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process",biological_process
90622,GO:1901852,"The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.","7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process",biological_process
90623,GO:1901854,"The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin.","5,6,7,8-tetrahydrosarcinapterin catabolic process",biological_process
90624,GO:1901855,"The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.","5,6,7,8-tetrahydrosarcinapterin biosynthetic process",biological_process
90625,GO:1901856,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.",negative regulation of cellular respiration,biological_process
90626,GO:1901857,"Any process that activates or increases the frequency, rate or extent of cellular respiration.",positive regulation of cellular respiration,biological_process
90627,GO:1901858,"Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.",regulation of mitochondrial DNA metabolic process,biological_process
90628,GO:1901859,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.",negative regulation of mitochondrial DNA metabolic process,biological_process
90629,GO:1901860,"Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.",positive regulation of mitochondrial DNA metabolic process,biological_process
90630,GO:1901861,"Any process that modulates the frequency, rate or extent of muscle tissue development.",regulation of muscle tissue development,biological_process
90631,GO:1901862,"Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.",negative regulation of muscle tissue development,biological_process
90632,GO:1901863,"Any process that activates or increases the frequency, rate or extent of muscle tissue development.",positive regulation of muscle tissue development,biological_process
90633,GO:1901865,The chemical reactions and pathways resulting in the breakdown of capsorubin.,capsorubin catabolic process,biological_process
90634,GO:1901866,The chemical reactions and pathways resulting in the formation of capsorubin.,capsorubin biosynthetic process,biological_process
90635,GO:1901868,The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.,ecgonine methyl ester catabolic process,biological_process
90636,GO:1901869,The chemical reactions and pathways resulting in the formation of ecgonine methyl ester.,ecgonine methyl ester biosynthetic process,biological_process
90637,GO:1901871,The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester.,ecgonone methyl ester catabolic process,biological_process
90638,GO:1901872,The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.,ecgonone methyl ester biosynthetic process,biological_process
90639,GO:1901873,"Any process that modulates the frequency, rate or extent of post-translational protein modification.",regulation of post-translational protein modification,biological_process
90640,GO:1901874,"Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.",negative regulation of post-translational protein modification,biological_process
90641,GO:1901875,"Any process that activates or increases the frequency, rate or extent of post-translational protein modification.",positive regulation of post-translational protein modification,biological_process
90642,GO:1901876,"Any process that modulates the frequency, rate or extent of calcium ion binding.",regulation of calcium ion binding,biological_process
90643,GO:1901879,"Any process that modulates the frequency, rate or extent of protein depolymerization.",regulation of protein depolymerization,biological_process
90644,GO:1901880,"Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.",negative regulation of protein depolymerization,biological_process
90645,GO:1901881,"Any process that activates or increases the frequency, rate or extent of protein depolymerization.",positive regulation of protein depolymerization,biological_process
90646,GO:1901883,The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin.,4-hydroxycoumarin catabolic process,biological_process
90647,GO:1901884,The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.,4-hydroxycoumarin biosynthetic process,biological_process
90648,GO:1901886,The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.,2-hydroxybenzoyl-CoA catabolic process,biological_process
90649,GO:1901887,The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.,2-hydroxybenzoyl-CoA biosynthetic process,biological_process
90650,GO:1901888,"Any process that modulates the frequency, rate or extent of cell junction assembly.",regulation of cell junction assembly,biological_process
90651,GO:1901889,"Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.",negative regulation of cell junction assembly,biological_process
90652,GO:1901890,"Any process that activates or increases the frequency, rate or extent of cell junction assembly.",positive regulation of cell junction assembly,biological_process
90653,GO:1901891,"Any process that modulates the frequency, rate or extent of cell septum assembly.",regulation of cell septum assembly,biological_process
90654,GO:1901892,"Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.",negative regulation of cell septum assembly,biological_process
90655,GO:1901893,"Any process that activates or increases the frequency, rate or extent of cell septum assembly.",positive regulation of cell septum assembly,biological_process
90656,GO:1901894,"Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.",regulation of ATPase-coupled calcium transmembrane transporter activity,biological_process
90657,GO:1901895,"Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.",negative regulation of ATPase-coupled calcium transmembrane transporter activity,biological_process
90658,GO:1901896,"Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.",positive regulation of ATPase-coupled calcium transmembrane transporter activity,biological_process
90659,GO:1901897,"Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.",regulation of relaxation of cardiac muscle,biological_process
90660,GO:1901898,"Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.",negative regulation of relaxation of cardiac muscle,biological_process
90661,GO:1901899,"Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.",positive regulation of relaxation of cardiac muscle,biological_process
90662,GO:1901900,"Any process that modulates the frequency, rate or extent of protein localization to cell division site.",regulation of protein localization to cell division site,biological_process
90663,GO:1901901,Any regulation of protein localization to cell division site that is involved in cytokinesis.,regulation of protein localization to cell division site involved in cytokinesis,biological_process
90664,GO:1901903,The chemical reactions and pathways resulting in the breakdown of tyrocidine.,tyrocidine catabolic process,biological_process
90665,GO:1901904,The chemical reactions and pathways resulting in the formation of tyrocidine.,tyrocidine biosynthetic process,biological_process
90666,GO:1901905,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.",response to tamsulosin,biological_process
90667,GO:1901907,The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.,diadenosine pentaphosphate catabolic process,biological_process
90668,GO:1901909,The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.,diadenosine hexaphosphate catabolic process,biological_process
90669,GO:1901911,The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).,adenosine 5'-(hexahydrogen pentaphosphate) catabolic process,biological_process
90670,GO:1901913,"Any process that modulates the frequency, rate or extent of capsule organization.",regulation of capsule organization,biological_process
90671,GO:1901914,"Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.",negative regulation of capsule organization,biological_process
90672,GO:1901915,"Any process that activates or increases the frequency, rate or extent of capsule organization.",positive regulation of capsule organization,biological_process
90673,GO:1901922,"Any process that modulates the frequency, rate or extent of sclerotium development.",regulation of sclerotium development,biological_process
90674,GO:1901923,"Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.",negative regulation of sclerotium development,biological_process
90675,GO:1901924,"Any process that activates or increases the frequency, rate or extent of sclerotium development.",positive regulation of sclerotium development,biological_process
90676,GO:1901925,"Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein...",negative regulation of protein import into nucleus during spindle assembly checkpoint,biological_process
90677,GO:1901927,The chemical reactions and pathways resulting in the breakdown of cadinene.,cadinene catabolic process,biological_process
90678,GO:1901928,The chemical reactions and pathways resulting in the formation of cadinene.,cadinene biosynthetic process,biological_process
90679,GO:1901930,The chemical reactions and pathways resulting in the breakdown of alpha-copaene.,alpha-copaene catabolic process,biological_process
90680,GO:1901931,The chemical reactions and pathways resulting in the formation of alpha-copaene.,alpha-copaene biosynthetic process,biological_process
90681,GO:1901933,The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene.,bicyclogermacrene catabolic process,biological_process
90682,GO:1901934,The chemical reactions and pathways resulting in the formation of bicyclogermacrene.,bicyclogermacrene biosynthetic process,biological_process
90683,GO:1901936,The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.,beta-caryophyllene catabolic process,biological_process
90684,GO:1901937,The chemical reactions and pathways resulting in the formation of beta-caryophyllene.,beta-caryophyllene biosynthetic process,biological_process
90685,GO:1901939,The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.,(-)-exo-alpha-bergamotene catabolic process,biological_process
90686,GO:1901940,The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene.,(-)-exo-alpha-bergamotene biosynthetic process,biological_process
90687,GO:1901942,The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.,(+)-epi-alpha-bisabolol catabolic process,biological_process
90688,GO:1901943,The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.,(+)-epi-alpha-bisabolol biosynthetic process,biological_process
90689,GO:1901945,The chemical reactions and pathways resulting in the breakdown of miltiradiene.,miltiradiene catabolic process,biological_process
90690,GO:1901946,The chemical reactions and pathways resulting in the formation of miltiradiene.,miltiradiene biosynthetic process,biological_process
90691,GO:1901948,"The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.","5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process",biological_process
90692,GO:1901949,"The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.","5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process",biological_process
90693,GO:1901950,The directed movement a dense core granule within a cell.,dense core granule transport,biological_process
90694,GO:1901951,"Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.",regulation of anterograde dense core granule transport,biological_process
90695,GO:1901952,"Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.",negative regulation of anterograde dense core granule transport,biological_process
90696,GO:1901953,"Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.",positive regulation of anterograde dense core granule transport,biological_process
90697,GO:1901954,"Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.",regulation of retrograde dense core granule transport,biological_process
90698,GO:1901955,"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.",negative regulation of retrograde dense core granule transport,biological_process
90699,GO:1901956,"Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.",positive regulation of retrograde dense core granule transport,biological_process
90700,GO:1901957,"Any process that modulates the frequency, rate or extent of cutin biosynthetic process.",regulation of cutin biosynthetic process,biological_process
90701,GO:1901958,"Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.",negative regulation of cutin biosynthetic process,biological_process
90702,GO:1901959,"Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.",positive regulation of cutin biosynthetic process,biological_process
90703,GO:1901961,The chemical reactions and pathways resulting in the formation of isobutanol.,isobutanol biosynthetic process,biological_process
90704,GO:1901962,The directed movement of S-adenosyl-L-methionine across a membrane.,S-adenosyl-L-methionine transmembrane transport,biological_process
90705,GO:1901965,The directed movement of substances from endoplasmic reticulum to chloroplast.,endoplasmic reticulum to chloroplast transport,biological_process
90706,GO:1901966,"Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.",regulation of cellular response to iron ion starvation,biological_process
90707,GO:1901967,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.",negative regulation of cellular response to iron ion starvation,biological_process
90708,GO:1901970,"Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.",positive regulation of mitotic sister chromatid separation,biological_process
90709,GO:1901973,Binding to proline.,proline binding,molecular_function
90710,GO:1901974,Enables the transfer of glycerate from one side of a membrane to the other.,glycerate transmembrane transporter activity,molecular_function
90711,GO:1901975,The process in which glycerate is transported across a membrane.,glycerate transmembrane transport,biological_process
90712,GO:1901976,"Any process that modulates the frequency, rate or extent of cell cycle checkpoint.",regulation of cell cycle checkpoint,biological_process
90713,GO:1901977,"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.",negative regulation of cell cycle checkpoint,biological_process
90714,GO:1901978,"Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.",positive regulation of cell cycle checkpoint,biological_process
90715,GO:1901981,Binding to phosphatidylinositol phosphate.,phosphatidylinositol phosphate binding,molecular_function
90716,GO:1901982,Binding to maltose.,maltose binding,molecular_function
90717,GO:1901983,"Any process that modulates the frequency, rate or extent of protein acetylation.",regulation of protein acetylation,biological_process
90718,GO:1901984,"Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.",negative regulation of protein acetylation,biological_process
90719,GO:1901985,"Any process that activates or increases the frequency, rate or extent of protein acetylation.",positive regulation of protein acetylation,biological_process
90720,GO:1901986,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.",response to ketamine,biological_process
90721,GO:1901987,"Any process that modulates the frequency, rate or extent of cell cycle phase transition.",regulation of cell cycle phase transition,biological_process
90722,GO:1901988,"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.",negative regulation of cell cycle phase transition,biological_process
90723,GO:1901989,"Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.",positive regulation of cell cycle phase transition,biological_process
90724,GO:1901990,"Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.",regulation of mitotic cell cycle phase transition,biological_process
90725,GO:1901991,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.",negative regulation of mitotic cell cycle phase transition,biological_process
90726,GO:1901992,"Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.",positive regulation of mitotic cell cycle phase transition,biological_process
90727,GO:1901993,"Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition.",regulation of meiotic cell cycle phase transition,biological_process
90728,GO:1901994,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition.",negative regulation of meiotic cell cycle phase transition,biological_process
90729,GO:1901995,"Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.",positive regulation of meiotic cell cycle phase transition,biological_process
90730,GO:1901997,"Any process that stops, prevents or reduces the frequency, rate or extent of auxin biosynthetic process.",negative regulation of auxin biosynthetic process,biological_process
90731,GO:1902000,The chemical reactions and pathways resulting in the breakdown of homogentisate.,homogentisate catabolic process,biological_process
90732,GO:1902001,The process in which a fatty acid is transported across a membrane.,fatty acid transmembrane transport,biological_process
90733,GO:1902003,"Any process that modulates the frequency, rate or extent of amyloid-beta formation.",regulation of amyloid-beta formation,biological_process
90734,GO:1902004,"Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.",positive regulation of amyloid-beta formation,biological_process
90735,GO:1902005,"Any process that modulates the frequency, rate or extent of L-proline biosynthetic process.",regulation of L-proline biosynthetic process,biological_process
90736,GO:1902006,"Any process that stops, prevents or reduces the frequency, rate or extent of L-proline biosynthetic process.",negative regulation of L-proline biosynthetic process,biological_process
90737,GO:1902010,"Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.",negative regulation of translation in response to endoplasmic reticulum stress,biological_process
90738,GO:1902012,The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.,poly(ribitol phosphate) teichoic acid biosynthetic process,biological_process
90739,GO:1902014,The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.,poly(glycerol phosphate) teichoic acid biosynthetic process,biological_process
90740,GO:1902016,The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.,poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process,biological_process
90741,GO:1902017,"Any process that modulates the frequency, rate or extent of cilium assembly.",regulation of cilium assembly,biological_process
90742,GO:1902018,"Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.",negative regulation of cilium assembly,biological_process
90743,GO:1902019,"Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.",regulation of cilium-dependent cell motility,biological_process
90744,GO:1902020,"Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.",negative regulation of cilium-dependent cell motility,biological_process
90745,GO:1902021,"Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.",regulation of bacterial-type flagellum-dependent cell motility,biological_process
90746,GO:1902022,"The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-lysine transport,biological_process
90747,GO:1902024,"The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",L-histidine transport,biological_process
90748,GO:1902025,The directed movement of nitrate into a cell or organelle.,nitrate import,biological_process
90749,GO:1902026,"Any process that modulates the frequency, rate or extent of cartilage condensation.",regulation of cartilage condensation,biological_process
90750,GO:1902027,"Any process that activates or increases the frequency, rate or extent of cartilage condensation.",positive regulation of cartilage condensation,biological_process
90751,GO:1902031,"Any process that modulates the frequency, rate or extent of NADP metabolic process.",regulation of NADP metabolic process,biological_process
90752,GO:1902033,"Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.",regulation of hematopoietic stem cell proliferation,biological_process
90753,GO:1902034,"Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.",negative regulation of hematopoietic stem cell proliferation,biological_process
90754,GO:1902035,"Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.",positive regulation of hematopoietic stem cell proliferation,biological_process
90755,GO:1902036,"Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.",regulation of hematopoietic stem cell differentiation,biological_process
90756,GO:1902037,"Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.",negative regulation of hematopoietic stem cell differentiation,biological_process
90757,GO:1902038,"Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.",positive regulation of hematopoietic stem cell differentiation,biological_process
90758,GO:1902039,"Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process.",negative regulation of seed dormancy process,biological_process
90759,GO:1902040,"Any process that activates or increases the frequency, rate or extent of seed dormancy process.",positive regulation of seed dormancy process,biological_process
90760,GO:1902041,"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.",regulation of extrinsic apoptotic signaling pathway via death domain receptors,biological_process
90761,GO:1902042,"Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.",negative regulation of extrinsic apoptotic signaling pathway via death domain receptors,biological_process
90762,GO:1902043,"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.",positive regulation of extrinsic apoptotic signaling pathway via death domain receptors,biological_process
90763,GO:1902044,"Any process that modulates the frequency, rate or extent of Fas signaling pathway.",regulation of Fas signaling pathway,biological_process
90764,GO:1902045,"Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.",negative regulation of Fas signaling pathway,biological_process
90765,GO:1902046,"Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.",positive regulation of Fas signaling pathway,biological_process
90766,GO:1902047,The process in which a polyamine macromolecule is transported across a membrane.,polyamine transmembrane transport,biological_process
90767,GO:1902049,The chemical reactions and pathways resulting in the breakdown of neosartoricin.,neosartoricin catabolic process,biological_process
90768,GO:1902050,The chemical reactions and pathways resulting in the formation of neosartoricin.,neosartoricin biosynthetic process,biological_process
90769,GO:1902051,Binding to (25S)-Delta(4)-dafachronate.,(25S)-Delta(4)-dafachronate binding,molecular_function
90770,GO:1902052,Binding to (25S)-Delta(7)-dafachronate.,(25S)-Delta(7)-dafachronate binding,molecular_function
90771,GO:1902053,"Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process.",regulation of neosartoricin biosynthetic process,biological_process
90772,GO:1902054,"Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process.",negative regulation of neosartoricin biosynthetic process,biological_process
90773,GO:1902055,"Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process.",positive regulation of neosartoricin biosynthetic process,biological_process
90774,GO:1902056,The chemical reactions and pathways resulting in the formation of (25S)-Delta(7)-dafachronate.,(25S)-Delta(7)-dafachronate biosynthetic process,biological_process
90775,GO:1902059,"Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.",negative regulation of sporocarp development involved in sexual reproduction,biological_process
90776,GO:1902060,"Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.",positive regulation of sporocarp development involved in sexual reproduction,biological_process
90777,GO:1902062,The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.,betaine aldehyde catabolic process,biological_process
90778,GO:1902063,The chemical reactions and pathways resulting in the formation of betaine aldehyde.,betaine aldehyde biosynthetic process,biological_process
90779,GO:1902065,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.",response to L-glutamate,biological_process
90780,GO:1902066,"Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.",regulation of cell wall pectin metabolic process,biological_process
90781,GO:1902068,"Any process that modulates the frequency, rate or extent of sphingolipid signaling.",regulation of sphingolipid mediated signaling pathway,biological_process
90782,GO:1902069,"Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.",negative regulation of sphingolipid mediated signaling pathway,biological_process
90783,GO:1902070,"Any process that activates or increases the frequency, rate or extent of sphingolipid signaling.",positive regulation of sphingolipid mediated signaling pathway,biological_process
90784,GO:1902071,"Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.",regulation of hypoxia-inducible factor-1alpha signaling pathway,biological_process
90785,GO:1902072,"Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.",negative regulation of hypoxia-inducible factor-1alpha signaling pathway,biological_process
90786,GO:1902073,"Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.",positive regulation of hypoxia-inducible factor-1alpha signaling pathway,biological_process
90787,GO:1902074,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.",response to salt,biological_process
90788,GO:1902075,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.",cellular response to salt,biological_process
90789,GO:1902076,"Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.",regulation of lateral motor column neuron migration,biological_process
90790,GO:1902077,"Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.",negative regulation of lateral motor column neuron migration,biological_process
90791,GO:1902078,"Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.",positive regulation of lateral motor column neuron migration,biological_process
90792,GO:1902080,"Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.",regulation of calcium ion import into sarcoplasmic reticulum,biological_process
90793,GO:1902081,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.",negative regulation of calcium ion import into sarcoplasmic reticulum,biological_process
90794,GO:1902082,"Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.",positive regulation of calcium ion import into sarcoplasmic reticulum,biological_process
90795,GO:1902083,"Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.",negative regulation of peptidyl-cysteine S-nitrosylation,biological_process
90796,GO:1902085,The chemical reactions and pathways resulting in the breakdown of fumagillin.,fumagillin catabolic process,biological_process
90797,GO:1902086,The chemical reactions and pathways resulting in the formation of fumagillin.,fumagillin biosynthetic process,biological_process
90798,GO:1902087,"The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.",dimethylsulfoniopropionate catabolic process,biological_process
90799,GO:1902090,"Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.",regulation of fumagillin biosynthetic process,biological_process
90800,GO:1902091,"Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.",negative regulation of fumagillin biosynthetic process,biological_process
90801,GO:1902092,"Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.",positive regulation of fumagillin biosynthetic process,biological_process
90802,GO:1902093,"Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.",positive regulation of flagellated sperm motility,biological_process
90803,GO:1902098,"Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.",calcitriol binding,molecular_function
90804,GO:1902099,"Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.",regulation of metaphase/anaphase transition of cell cycle,biological_process
90805,GO:1902100,"Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.",negative regulation of metaphase/anaphase transition of cell cycle,biological_process
90806,GO:1902101,"Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.",positive regulation of metaphase/anaphase transition of cell cycle,biological_process
90807,GO:1902102,"Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.",regulation of metaphase/anaphase transition of meiotic cell cycle,biological_process
90808,GO:1902103,"Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.",negative regulation of metaphase/anaphase transition of meiotic cell cycle,biological_process
90809,GO:1902104,"Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.",positive regulation of metaphase/anaphase transition of meiotic cell cycle,biological_process
90810,GO:1902105,"Any process that modulates the frequency, rate or extent of leukocyte differentiation.",regulation of leukocyte differentiation,biological_process
90811,GO:1902106,"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.",negative regulation of leukocyte differentiation,biological_process
90812,GO:1902107,"Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.",positive regulation of leukocyte differentiation,biological_process
90813,GO:1902108,Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.,regulation of mitochondrial membrane permeability involved in apoptotic process,biological_process
90814,GO:1902109,Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.,negative regulation of mitochondrial membrane permeability involved in apoptotic process,biological_process
90815,GO:1902110,Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.,positive regulation of mitochondrial membrane permeability involved in apoptotic process,biological_process
90816,GO:1902111,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.",response to diethyl maleate,biological_process
90817,GO:1902112,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.",cellular response to diethyl maleate,biological_process
90818,GO:1902115,"Any process that modulates the frequency, rate or extent of organelle assembly.",regulation of organelle assembly,biological_process
90819,GO:1902116,"Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.",negative regulation of organelle assembly,biological_process
90820,GO:1902117,"Any process that activates or increases the frequency, rate or extent of organelle assembly.",positive regulation of organelle assembly,biological_process
90821,GO:1902118,Binding to calcidiol.,calcidiol binding,molecular_function
90822,GO:1902119,"Any process that modulates the frequency, rate or extent of meiotic spindle elongation.",regulation of meiotic spindle elongation,biological_process
90823,GO:1902120,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.",negative regulation of meiotic spindle elongation,biological_process
90824,GO:1902121,Binding to lithocholic acid.,lithocholic acid binding,molecular_function
90825,GO:1902122,Binding to chenodeoxycholic acid.,chenodeoxycholic acid binding,molecular_function
90826,GO:1902123,The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol.,(-)-pinoresinol catabolic process,biological_process
90827,GO:1902125,The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol.,(+)-pinoresinol catabolic process,biological_process
90828,GO:1902126,The chemical reactions and pathways resulting in the formation of (+)-pinoresinol.,(+)-pinoresinol biosynthetic process,biological_process
90829,GO:1902128,The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.,(-)-lariciresinol catabolic process,biological_process
90830,GO:1902129,The chemical reactions and pathways resulting in the formation of (-)-lariciresinol.,(-)-lariciresinol biosynthetic process,biological_process
90831,GO:1902131,The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol.,(+)-lariciresinol catabolic process,biological_process
90832,GO:1902132,The chemical reactions and pathways resulting in the formation of (+)-lariciresinol.,(+)-lariciresinol biosynthetic process,biological_process
90833,GO:1902134,The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol.,(+)-secoisolariciresinol catabolic process,biological_process
90834,GO:1902135,The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.,(+)-secoisolariciresinol biosynthetic process,biological_process
90835,GO:1902137,The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol.,(-)-secoisolariciresinol catabolic process,biological_process
90836,GO:1902138,The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol.,(-)-secoisolariciresinol biosynthetic process,biological_process
90837,GO:1902140,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.",response to inositol,biological_process
90838,GO:1902141,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.",cellular response to inositol,biological_process
90839,GO:1902145,"Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.",regulation of response to cell cycle checkpoint signaling,biological_process
90840,GO:1902146,"Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling.",positive regulation of response to cell cycle checkpoint signaling,biological_process
90841,GO:1902147,"Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.",regulation of response to cytokinesis checkpoint signaling,biological_process
90842,GO:1902148,"Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.",positive regulation of response to cytokinesis checkpoint signaling,biological_process
90843,GO:1902151,"Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.",regulation of response to DNA integrity checkpoint signaling,biological_process
90844,GO:1902152,"Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.",positive regulation of response to DNA integrity checkpoint signaling,biological_process
90845,GO:1902153,"Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling.",regulation of response to DNA damage checkpoint signaling,biological_process
90846,GO:1902154,"Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling.",positive regulation of response to DNA damage checkpoint signaling,biological_process
90847,GO:1902155,"Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.",regulation of response to G1 DNA damage checkpoint signaling,biological_process
90848,GO:1902156,"Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.",positive regulation of response to G1 DNA damage checkpoint signaling,biological_process
90849,GO:1902157,"Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.",regulation of response to G2 DNA damage checkpoint signaling,biological_process
90850,GO:1902158,"Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.",positive regulation of response to G2 DNA damage checkpoint signaling,biological_process
90851,GO:1902159,"Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.",regulation of cyclic nucleotide-gated ion channel activity,biological_process
90852,GO:1902165,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.",regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,biological_process
90853,GO:1902166,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.",negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,biological_process
90854,GO:1902167,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.",positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,biological_process
90855,GO:1902168,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.",response to catechin,biological_process
90856,GO:1902169,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.",cellular response to catechin,biological_process
90857,GO:1902170,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.",cellular response to reactive nitrogen species,biological_process
90858,GO:1902171,"Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.",regulation of tocopherol cyclase activity,biological_process
90859,GO:1902172,"Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.",regulation of keratinocyte apoptotic process,biological_process
90860,GO:1902173,"Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.",negative regulation of keratinocyte apoptotic process,biological_process
90861,GO:1902174,"Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.",positive regulation of keratinocyte apoptotic process,biological_process
90862,GO:1902175,"Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.",regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,biological_process
90863,GO:1902176,"Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.",negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,biological_process
90864,GO:1902177,"Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.",positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,biological_process
90865,GO:1902178,"An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).",fibroblast growth factor receptor apoptotic signaling pathway,biological_process
90866,GO:1902181,The chemical reactions and pathways resulting in the formation of verruculogen.,verruculogen biosynthetic process,biological_process
90867,GO:1902182,"The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.",shoot apical meristem development,biological_process
90868,GO:1902183,"Any process that modulates the frequency, rate or extent of shoot apical meristem development.",regulation of shoot apical meristem development,biological_process
90869,GO:1902184,"Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.",negative regulation of shoot apical meristem development,biological_process
90870,GO:1902185,"Any process that activates or increases the frequency, rate or extent of shoot apical meristem development.",positive regulation of shoot apical meristem development,biological_process
90871,GO:1902190,The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-).,2-methylbutanoyl-CoA(4-) catabolic process,biological_process
90872,GO:1902191,The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).,2-methylbutanoyl-CoA(4-) biosynthetic process,biological_process
90873,GO:1902192,The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).,2-methylbut-2-enoyl-CoA(4-) metabolic process,biological_process
90874,GO:1902193,The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-).,2-methylbut-2-enoyl-CoA(4-) catabolic process,biological_process
90875,GO:1902194,The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-).,2-methylbut-2-enoyl-CoA(4-) biosynthetic process,biological_process
90876,GO:1902196,The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).,isovaleryl-CoA(4-) catabolic process,biological_process
90877,GO:1902197,The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-).,isovaleryl-CoA(4-) biosynthetic process,biological_process
90878,GO:1902198,The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).,3-methylbut-2-enoyl-CoA(4-) metabolic process,biological_process
90879,GO:1902199,The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).,3-methylbut-2-enoyl-CoA(4-) catabolic process,biological_process
90880,GO:1902200,The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-).,3-methylbut-2-enoyl-CoA(4-) biosynthetic process,biological_process
90881,GO:1902201,"Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.",negative regulation of bacterial-type flagellum-dependent cell motility,biological_process
90882,GO:1902202,"Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.",regulation of hepatocyte growth factor receptor signaling pathway,biological_process
90883,GO:1902203,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.",negative regulation of hepatocyte growth factor receptor signaling pathway,biological_process
90884,GO:1902204,"Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.",positive regulation of hepatocyte growth factor receptor signaling pathway,biological_process
90885,GO:1902205,"Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.",regulation of interleukin-2-mediated signaling pathway,biological_process
90886,GO:1902206,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.",negative regulation of interleukin-2-mediated signaling pathway,biological_process
90887,GO:1902207,"Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.",positive regulation of interleukin-2-mediated signaling pathway,biological_process
90888,GO:1902208,"Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.",regulation of bacterial-type flagellum assembly,biological_process
90889,GO:1902209,"Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.",negative regulation of bacterial-type flagellum assembly,biological_process
90890,GO:1902210,"Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.",positive regulation of bacterial-type flagellum assembly,biological_process
90891,GO:1902211,"Any process that modulates the frequency, rate or extent of prolactin signaling pathway.",regulation of prolactin signaling pathway,biological_process
90892,GO:1902212,"Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.",negative regulation of prolactin signaling pathway,biological_process
90893,GO:1902213,"Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.",positive regulation of prolactin signaling pathway,biological_process
90894,GO:1902214,"Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.",regulation of interleukin-4-mediated signaling pathway,biological_process
90895,GO:1902215,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.",negative regulation of interleukin-4-mediated signaling pathway,biological_process
90896,GO:1902216,"Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.",positive regulation of interleukin-4-mediated signaling pathway,biological_process
90897,GO:1902217,Any apoptotic process in an erythrocyte.,erythrocyte apoptotic process,biological_process
90898,GO:1902218,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.",regulation of intrinsic apoptotic signaling pathway in response to osmotic stress,biological_process
90899,GO:1902219,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.",negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress,biological_process
90900,GO:1902220,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.",positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress,biological_process
90901,GO:1902223,"The chemical reactions and pathways resulting in the formation of an L-amino acid derived from erythrose 4-phosphate and phosphoenolpyruvate (L-phenylalanine, L-tyrosine and L-tryptophan).",erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process,biological_process
90902,GO:1902225,"Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.",negative regulation of acrosome reaction,biological_process
90903,GO:1902226,"Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.",regulation of macrophage colony-stimulating factor signaling pathway,biological_process
90904,GO:1902227,"Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.",negative regulation of macrophage colony-stimulating factor signaling pathway,biological_process
90905,GO:1902228,"Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.",positive regulation of macrophage colony-stimulating factor signaling pathway,biological_process
90906,GO:1902229,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.",regulation of intrinsic apoptotic signaling pathway in response to DNA damage,biological_process
90907,GO:1902230,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.",negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage,biological_process
90908,GO:1902231,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.",positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage,biological_process
90909,GO:1902232,"Any process that modulates the frequency, rate or extent of positive thymic T cell selection.",regulation of positive thymic T cell selection,biological_process
90910,GO:1902233,"Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.",negative regulation of positive thymic T cell selection,biological_process
90911,GO:1902234,"Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.",positive regulation of positive thymic T cell selection,biological_process
90912,GO:1902235,"Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.",regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway,biological_process
90913,GO:1902236,"Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.",negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway,biological_process
90914,GO:1902237,"Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.",positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway,biological_process
90915,GO:1902238,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.",regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator,biological_process
90916,GO:1902239,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.",negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator,biological_process
90917,GO:1902240,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.",positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator,biological_process
90918,GO:1902242,The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-).,copal-8-ol diphosphate(3-) catabolic process,biological_process
90919,GO:1902243,The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-).,copal-8-ol diphosphate(3-) biosynthetic process,biological_process
90920,GO:1902245,The chemical reactions and pathways resulting in the breakdown of cis-abienol.,cis-abienol catabolic process,biological_process
90921,GO:1902246,The chemical reactions and pathways resulting in the formation of cis-abienol.,cis-abienol biosynthetic process,biological_process
90922,GO:1902247,The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.,geranylgeranyl diphosphate catabolic process,biological_process
90923,GO:1902248,Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.,5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding,molecular_function
90924,GO:1902249,"Binding to IMP, inosine monophosphate.",IMP binding,molecular_function
90925,GO:1902250,"Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.",regulation of erythrocyte apoptotic process,biological_process
90926,GO:1902251,"Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.",negative regulation of erythrocyte apoptotic process,biological_process
90927,GO:1902252,"Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.",positive regulation of erythrocyte apoptotic process,biological_process
90928,GO:1902253,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.",regulation of intrinsic apoptotic signaling pathway by p53 class mediator,biological_process
90929,GO:1902254,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.",negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator,biological_process
90930,GO:1902255,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.",positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator,biological_process
90931,GO:1902256,"Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.",regulation of apoptotic process involved in outflow tract morphogenesis,biological_process
90932,GO:1902257,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.",negative regulation of apoptotic process involved in outflow tract morphogenesis,biological_process
90933,GO:1902259,"Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.",regulation of delayed rectifier potassium channel activity,biological_process
90934,GO:1902260,"Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.",negative regulation of delayed rectifier potassium channel activity,biological_process
90935,GO:1902262,Any apoptotic process that is involved in blood vessel morphogenesis.,apoptotic process involved in blood vessel morphogenesis,biological_process
90936,GO:1902263,Any apoptotic process that is involved in embryonic digit morphogenesis.,apoptotic process involved in embryonic digit morphogenesis,biological_process
90937,GO:1902265,Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.,abscisic acid homeostasis,biological_process
90938,GO:1902266,A homeostatic process involved in the maintenance of a steady state level of abscisic acid within a cell.,intracellular abscisic acid homeostasis,biological_process
90939,GO:1902267,"Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.",regulation of polyamine transmembrane transport,biological_process
90940,GO:1902268,"Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.",negative regulation of polyamine transmembrane transport,biological_process
90941,GO:1902269,"Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.",positive regulation of polyamine transmembrane transport,biological_process
90942,GO:1902270,The process in which (R)-carnitine is transported across a membrane.,(R)-carnitine transmembrane transport,biological_process
90943,GO:1902271,Binding to D3 vitamins.,D3 vitamins binding,molecular_function
90944,GO:1902272,"Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport.",regulation of (R)-carnitine transmembrane transport,biological_process
90945,GO:1902273,"Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport.",negative regulation of (R)-carnitine transmembrane transport,biological_process
90946,GO:1902274,"Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.",positive regulation of (R)-carnitine transmembrane transport,biological_process
90947,GO:1902275,"Any process that modulates the frequency, rate or extent of chromatin organization.",regulation of chromatin organization,biological_process
90948,GO:1902276,"Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.",regulation of pancreatic amylase secretion,biological_process
90949,GO:1902277,"Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.",negative regulation of pancreatic amylase secretion,biological_process
90950,GO:1902278,"Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.",positive regulation of pancreatic amylase secretion,biological_process
90951,GO:1902279,A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.,positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway,biological_process
90952,GO:1902280,"Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.",regulation of RNA helicase activity,biological_process
90953,GO:1902282,Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.,voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization,molecular_function
90954,GO:1902287,Any semaphorin-plexin signaling pathway that is involved in axon guidance.,semaphorin-plexin signaling pathway involved in axon guidance,biological_process
90955,GO:1902288,"Any process that modulates the frequency, rate or extent of defense response to oomycetes.",regulation of defense response to oomycetes,biological_process
90956,GO:1902289,"Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes.",negative regulation of defense response to oomycetes,biological_process
90957,GO:1902290,"Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.",positive regulation of defense response to oomycetes,biological_process
90958,GO:1902292,Any DNA replication initiation that is involved in cell cycle DNA replication.,cell cycle DNA replication initiation,biological_process
90959,GO:1902294,Any DNA replication termination that is involved in cell cycle DNA replication.,cell cycle DNA replication termination,biological_process
90960,GO:1902296,Any DNA strand elongation that is involved in cell cycle DNA replication.,DNA strand elongation involved in cell cycle DNA replication,biological_process
90961,GO:1902298,Any maintenance of fidelity that is involved in cell cycle DNA replication.,cell cycle DNA replication maintenance of fidelity,biological_process
90962,GO:1902299,Any pre-replicative complex assembly that is involved in cell cycle DNA replication.,pre-replicative complex assembly involved in cell cycle DNA replication,biological_process
90963,GO:1902300,"The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other.",galactarate transmembrane transport,biological_process
90964,GO:1902301,Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other.,galactarate transmembrane transporter activity,molecular_function
90965,GO:1902305,"Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.",regulation of sodium ion transmembrane transport,biological_process
90966,GO:1902306,"Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.",negative regulation of sodium ion transmembrane transport,biological_process
90967,GO:1902307,"Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.",positive regulation of sodium ion transmembrane transport,biological_process
90968,GO:1902311,"Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.",regulation of copper ion transmembrane transport,biological_process
90969,GO:1902312,"Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport.",negative regulation of copper ion transmembrane transport,biological_process
90970,GO:1902313,"Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.",positive regulation of copper ion transmembrane transport,biological_process
90971,GO:1902314,Binding to hydroquinone.,hydroquinone binding,molecular_function
90972,GO:1902315,Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.,nuclear cell cycle DNA replication initiation,biological_process
90973,GO:1902317,Any DNA replication termination that is involved in nuclear cell cycle DNA replication.,nuclear DNA replication termination,biological_process
90974,GO:1902319,Any DNA strand elongation that is involved in nuclear cell cycle DNA replication.,DNA strand elongation involved in nuclear cell cycle DNA replication,biological_process
90975,GO:1902321,The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid.,methyl-branched fatty acid biosynthetic process,biological_process
90976,GO:1902322,"Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.",regulation of methyl-branched fatty acid biosynthetic process,biological_process
90977,GO:1902323,"Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.",negative regulation of methyl-branched fatty acid biosynthetic process,biological_process
90978,GO:1902324,"Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.",positive regulation of methyl-branched fatty acid biosynthetic process,biological_process
90979,GO:1902325,"Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.",negative regulation of chlorophyll biosynthetic process,biological_process
90980,GO:1902326,"Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process.",positive regulation of chlorophyll biosynthetic process,biological_process
90981,GO:1902328,Any DNA replication initiation that is involved in bacterial-type DNA replication.,bacterial-type DNA replication initiation,biological_process
90982,GO:1902329,Any DNA replication termination that is involved in bacterial-type DNA replication.,bacterial-type DNA replication termination,biological_process
90983,GO:1902334,The directed movement of fructose from vacuole to cytoplasm.,fructose export from vacuole to cytoplasm,biological_process
90984,GO:1902336,"Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.",positive regulation of retinal ganglion cell axon guidance,biological_process
90985,GO:1902338,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.",negative regulation of apoptotic process involved in morphogenesis,biological_process
90986,GO:1902339,"Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.",positive regulation of apoptotic process involved in morphogenesis,biological_process
90987,GO:1902340,"Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.",negative regulation of chromosome condensation,biological_process
90988,GO:1902341,"The directed movement of a xylitol across a membrane. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose.",xylitol transmembrane transport,biological_process
90989,GO:1902343,"Any process that modulates the frequency, rate or extent of maltose transport.",regulation of maltose transport,biological_process
90990,GO:1902344,"Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.",negative regulation of maltose transport,biological_process
90991,GO:1902345,"Any process that activates or increases the frequency, rate or extent of maltose transport.",positive regulation of maltose transport,biological_process
90992,GO:1902346,Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA).,meiotic strand displacement involved in double-strand break repair via SDSA,biological_process
90993,GO:1902347,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.",response to strigolactone,biological_process
90994,GO:1902348,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.",cellular response to strigolactone,biological_process
90995,GO:1902349,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.",response to chloroquine,biological_process
90996,GO:1902350,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.",cellular response to chloroquine,biological_process
90997,GO:1902351,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus.",response to imidacloprid,biological_process
90998,GO:1902354,Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment.,blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment,biological_process
90999,GO:1902355,Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment.,endothelial tube lumen extension involved in blood vessel lumen ensheathment,biological_process
91000,GO:1902356,The directed movement of oxaloacetate(2-) across a membrane.,oxaloacetate(2-) transmembrane transport,biological_process
91001,GO:1902357,The process in which 2-isopropylmalate(2-) is transported across a membrane.,2-isopropylmalate(2-) transmembrane transport,biological_process
91002,GO:1902358,The directed movement of sulfate across a membrane.,sulfate transmembrane transport,biological_process
91003,GO:1902362,"Any apoptotic process in a melanocyte, the main structural component of the epidermis.",melanocyte apoptotic process,biological_process
91004,GO:1902363,"Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.",regulation of protein localization to spindle pole body,biological_process
91005,GO:1902364,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.",negative regulation of protein localization to spindle pole body,biological_process
91006,GO:1902365,"Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.",positive regulation of protein localization to spindle pole body,biological_process
91007,GO:1902369,"Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.",negative regulation of RNA catabolic process,biological_process
91008,GO:1902370,"Any process that modulates the frequency, rate or extent of tRNA catabolic process.",regulation of tRNA catabolic process,biological_process
91009,GO:1902371,"Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.",negative regulation of tRNA catabolic process,biological_process
91010,GO:1902372,"Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.",positive regulation of tRNA catabolic process,biological_process
91011,GO:1902373,"Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.",negative regulation of mRNA catabolic process,biological_process
91012,GO:1902374,"Any process that modulates the frequency, rate or extent of rRNA catabolic process.",regulation of rRNA catabolic process,biological_process
91013,GO:1902379,Any chemoattractant activity that is involved in axon guidance.,chemoattractant activity involved in axon guidance,molecular_function
91014,GO:1902382,The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.,11-oxo-beta-amyrin catabolic process,biological_process
91015,GO:1902383,The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin.,11-oxo-beta-amyrin biosynthetic process,biological_process
91016,GO:1902385,The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.,glycyrrhetinate catabolic process,biological_process
91017,GO:1902386,The chemical reactions and pathways resulting in the formation of glycyrrhetinate.,glycyrrhetinate biosynthetic process,biological_process
91018,GO:1902387,Binding to ceramide 1-phosphate.,ceramide 1-phosphate binding,molecular_function
91019,GO:1902388,"Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",ceramide 1-phosphate transfer activity,molecular_function
91020,GO:1902389,"The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",ceramide 1-phosphate transport,biological_process
91021,GO:1902396,"A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.",protein localization to bicellular tight junction,biological_process
91022,GO:1902404,Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.,mitotic actomyosin contractile ring contraction,biological_process
91023,GO:1902406,The cellular process in which the mitotic contractile ring cytokinetic ring attains its fully functional state.,mitotic actomyosin contractile ring maturation,biological_process
91024,GO:1902407,Any assembly of mitotic cytokinetic actomyosin apparatus.,assembly of actomyosin apparatus involved in mitotic cytokinesis,biological_process
91025,GO:1902408,The process in which a contractile ring is positioned in a specific location during the mitotic cell cycle. This process is critical for both for both symmetric and asymmetric cell divisions.,"mitotic cytokinesis, division site positioning",biological_process
91026,GO:1902410,Any cytokinetic process that is involved in mitotic cell cycle.,mitotic cytokinetic process,biological_process
91027,GO:1902412,"Any process that modulates the frequency, rate or extent of mitotic cytokinesis.",regulation of mitotic cytokinesis,biological_process
91028,GO:1902413,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.",negative regulation of mitotic cytokinesis,biological_process
91029,GO:1902414,"A process in which a protein is transported to, or maintained in, a location within a cell junction.",protein localization to cell junction,biological_process
91030,GO:1902415,"Any process that modulates the frequency, rate or extent of mRNA binding.",regulation of mRNA binding,biological_process
91031,GO:1902416,"Any process that activates or increases the frequency, rate or extent of mRNA binding.",positive regulation of mRNA binding,biological_process
91032,GO:1902417,Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.,(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity,molecular_function
91033,GO:1902418,The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane.,(+)-abscisic acid D-glucopyranosyl ester transmembrane transport,biological_process
91034,GO:1902421,The chemical reactions and pathways involving H2 (dihydrogen).,hydrogen metabolic process,biological_process
91035,GO:1902422,The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).,hydrogen biosynthetic process,biological_process
91036,GO:1902423,"Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.",regulation of attachment of mitotic spindle microtubules to kinetochore,biological_process
91037,GO:1902424,"Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.",negative regulation of attachment of mitotic spindle microtubules to kinetochore,biological_process
91038,GO:1902425,"Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.",positive regulation of attachment of mitotic spindle microtubules to kinetochore,biological_process
91039,GO:1902426,A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.,deactivation of mitotic spindle assembly checkpoint,biological_process
91040,GO:1902427,"Any process that modulates the frequency, rate or extent of water channel activity.",regulation of water channel activity,biological_process
91041,GO:1902430,"Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.",negative regulation of amyloid-beta formation,biological_process
91042,GO:1902432,"A process in which a protein is transported to, or maintained in, a location within a division septum.",protein localization to division septum,biological_process
91043,GO:1902434,"The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.",sulfate import across plasma membrane,biological_process
91044,GO:1902435,"Any process that modulates the frequency, rate or extent of male mating behavior.",regulation of male mating behavior,biological_process
91045,GO:1902436,"Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.",negative regulation of male mating behavior,biological_process
91046,GO:1902437,"Any process that activates or increases the frequency, rate or extent of male mating behavior.",positive regulation of male mating behavior,biological_process
91047,GO:1902438,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.",response to vanadate(3-),biological_process
91048,GO:1902439,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.",cellular response to vanadate(3-),biological_process
91049,GO:1902440,"A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.",protein localization to mitotic spindle pole body,biological_process
91050,GO:1902441,"A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.",protein localization to meiotic spindle pole body,biological_process
91051,GO:1902443,"Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.",negative regulation of ripoptosome assembly involved in necroptotic process,biological_process
91052,GO:1902444,Binding to riboflavin.,riboflavin binding,molecular_function
91053,GO:1902445,Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.,regulation of mitochondrial membrane permeability involved in programmed necrotic cell death,biological_process
91054,GO:1902446,"Any process that modulates the frequency, rate or extent of shade avoidance.",regulation of shade avoidance,biological_process
91055,GO:1902447,"Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance.",negative regulation of shade avoidance,biological_process
91056,GO:1902448,"Any process that activates or increases the frequency, rate or extent of shade avoidance.",positive regulation of shade avoidance,biological_process
91057,GO:1902455,"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.",negative regulation of stem cell population maintenance,biological_process
91058,GO:1902456,"Any process that modulates the frequency, rate or extent of stomatal opening.",regulation of stomatal opening,biological_process
91059,GO:1902457,"Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening.",negative regulation of stomatal opening,biological_process
91060,GO:1902458,"Any process that activates or increases the frequency, rate or extent of stomatal opening.",positive regulation of stomatal opening,biological_process
91061,GO:1902459,"Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.",positive regulation of stem cell population maintenance,biological_process
91062,GO:1902460,"Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.",regulation of mesenchymal stem cell proliferation,biological_process
91063,GO:1902461,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.",negative regulation of mesenchymal stem cell proliferation,biological_process
91064,GO:1902462,"Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.",positive regulation of mesenchymal stem cell proliferation,biological_process
91065,GO:1902463,"A process in which a protein is transported to, or maintained in, a location within a cell leading edge.",protein localization to cell leading edge,biological_process
91066,GO:1902472,"Any process that modulates the frequency, rate or extent of mitotic cytokinesis, division site positioning.","regulation of mitotic cytokinesis, division site positioning",biological_process
91067,GO:1902473,"Any process that modulates the frequency, rate or extent of protein localization to synapse.",regulation of protein localization to synapse,biological_process
91068,GO:1902474,"Any process that activates or increases the frequency, rate or extent of protein localization to synapse.",positive regulation of protein localization to synapse,biological_process
91069,GO:1902475,The directed movement of L-alpha-amino acid across a membrane by means of some agent such as a transporter or a pore.,L-alpha-amino acid transmembrane transport,biological_process
91070,GO:1902476,The process in which chloride is transported across a membrane.,chloride transmembrane transport,biological_process
91071,GO:1902480,"A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.",protein localization to mitotic spindle,biological_process
91072,GO:1902481,"The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.",gamma-tubulin complex assembly,biological_process
91073,GO:1902482,Any apoptotic process in a regulatory T cell.,regulatory T cell apoptotic process,biological_process
91074,GO:1902483,A pyroptotic cell death process that occurs in a cytotoxic T cell.,cytotoxic T cell pyroptotic cell death,biological_process
91075,GO:1902484,Any apoptotic process in a Sertoli cell.,Sertoli cell apoptotic process,biological_process
91076,GO:1902485,Binding to L-cysteine.,L-cysteine binding,molecular_function
91077,GO:1902486,"A process in which a protein is transported to, or maintained in, a location within a growing cell tip.",protein localization to growing cell tip,biological_process
91078,GO:1902487,"A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.",protein localization to non-growing cell tip,biological_process
91079,GO:1902488,Any apoptotic process in a cholangiocyte.,cholangiocyte apoptotic process,biological_process
91080,GO:1902489,Any apoptotic process in a hepatoblast.,hepatoblast apoptotic process,biological_process
91081,GO:1902490,"Any process that modulates the frequency, rate or extent of sperm capacitation.",regulation of sperm capacitation,biological_process
91082,GO:1902491,"Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.",negative regulation of sperm capacitation,biological_process
91083,GO:1902492,"Any process that activates or increases the frequency, rate or extent of sperm capacitation.",positive regulation of sperm capacitation,biological_process
91084,GO:1902493,A protein complex which is capable of acetyltransferase activity.,acetyltransferase complex,cellular_component
91085,GO:1902494,A protein complex which is capable of catalytic activity.,catalytic complex,cellular_component
91086,GO:1902495,A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.,transmembrane transporter complex,cellular_component
91087,GO:1902497,A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.,iron-sulfur cluster transmembrane transport,biological_process
91088,GO:1902498,"Any process that modulates the frequency, rate or extent of protein autoubiquitination.",regulation of protein autoubiquitination,biological_process
91089,GO:1902499,"Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.",positive regulation of protein autoubiquitination,biological_process
91090,GO:1902500,Any HOPS complex that is part of a vacuolar membrane.,vacuolar HOPS complex,cellular_component
91091,GO:1902501,Any HOPS complex that is part of a lysosomal membrane.,lysosomal HOPS complex,cellular_component
91092,GO:1902502,Any HOPS complex that is part of a multivesicular body membrane.,multivesicular body HOPS complex,cellular_component
91093,GO:1902503,A protein complex which is capable of adenylyltransferase activity.,adenylyltransferase complex,cellular_component
91094,GO:1902507,A protein complex which is capable of thiazole synthase activity.,thiazole synthase complex,cellular_component
91095,GO:1902508,A protein complex which is capable of 2-iminoacetate synthase activity.,2-iminoacetate synthase complex,cellular_component
91096,GO:1902509,A protein complex which is capable of methionine-importing activity.,methionine-importing complex,cellular_component
91097,GO:1902510,"Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.",regulation of apoptotic DNA fragmentation,biological_process
91098,GO:1902511,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.",negative regulation of apoptotic DNA fragmentation,biological_process
91099,GO:1902512,"Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.",positive regulation of apoptotic DNA fragmentation,biological_process
91100,GO:1902513,"Any process that modulates the frequency, rate or extent of organelle transport along microtubule.",regulation of organelle transport along microtubule,biological_process
91101,GO:1902514,"Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.",regulation of calcium ion transmembrane transport via high voltage-gated calcium channel,biological_process
91102,GO:1902515,A protein complex which is capable of thioredoxin-disulfide reductase activity.,thioredoxin-disulfide reductase complex,cellular_component
91103,GO:1902516,Binding to sn-glycerol 3-phosphate.,sn-glycerol 3-phosphate binding,molecular_function
91104,GO:1902517,A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity.,glycerol-3-phosphate-transporting ATPase complex,cellular_component
91105,GO:1902518,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.",response to cyclophosphamide,biological_process
91106,GO:1902519,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.",response to docetaxel trihydrate,biological_process
91107,GO:1902520,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.",response to doxorubicin,biological_process
91108,GO:1902521,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.",response to etoposide,biological_process
91109,GO:1902522,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.",response to 4'-epidoxorubicin,biological_process
91110,GO:1902523,"Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.",positive regulation of protein K63-linked ubiquitination,biological_process
91111,GO:1902524,"Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.",positive regulation of protein K48-linked ubiquitination,biological_process
91112,GO:1902525,"Any process that modulates the frequency, rate or extent of protein monoubiquitination.",regulation of protein monoubiquitination,biological_process
91113,GO:1902526,"Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination.",negative regulation of protein monoubiquitination,biological_process
91114,GO:1902527,"Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.",positive regulation of protein monoubiquitination,biological_process
91115,GO:1902528,"Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.",regulation of protein linear polyubiquitination,biological_process
91116,GO:1902529,"Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination.",negative regulation of protein linear polyubiquitination,biological_process
91117,GO:1902530,"Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.",positive regulation of protein linear polyubiquitination,biological_process
91118,GO:1902531,"Any process that modulates the frequency, rate or extent of intracellular signal transduction.",regulation of intracellular signal transduction,biological_process
91119,GO:1902532,"Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.",negative regulation of intracellular signal transduction,biological_process
91120,GO:1902533,"Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.",positive regulation of intracellular signal transduction,biological_process
91121,GO:1902542,"Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.",regulation of protein localization to mitotic spindle pole body,biological_process
91122,GO:1902543,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.",negative regulation of protein localization to mitotic spindle pole body,biological_process
91123,GO:1902547,"Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.",regulation of cellular response to vascular endothelial growth factor stimulus,biological_process
91124,GO:1902548,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.",negative regulation of cellular response to vascular endothelial growth factor stimulus,biological_process
91125,GO:1902549,"A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.",protein localization to Mei2 nuclear dot,biological_process
91126,GO:1902553,"Any process that activates or increases the frequency, rate or extent of catalase activity.",positive regulation of catalase activity,biological_process
91127,GO:1902554,A protein complex which is capable of protein serine/threonine kinase activity.,serine/threonine protein kinase complex,cellular_component
91128,GO:1902555,A protein complex which is capable of endoribonuclease activity.,endoribonuclease complex,cellular_component
91129,GO:1902556,A protein complex which is capable of phosphatidylinositol transporter activity.,phosphatidylinositol transporter complex,cellular_component
91130,GO:1902557,Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.,5'-adenylyl sulfate transmembrane transporter activity,molecular_function
91131,GO:1902558,The process in which 5'-adenylyl sulfate is transported across a membrane.,5'-adenylyl sulfate transmembrane transport,biological_process
91132,GO:1902559,The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane.,3'-phospho-5'-adenylyl sulfate transmembrane transport,biological_process
91133,GO:1902560,An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H+ + NADPH => IMP + NADP+ + NH4.,GMP reductase complex,cellular_component
91134,GO:1902561,"The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex.",origin recognition complex assembly,biological_process
91135,GO:1902562,A protein complex which is capable of H4 histone acetyltransferase activity.,H4 histone acetyltransferase complex,cellular_component
91136,GO:1902563,"Any process that modulates the frequency, rate or extent of neutrophil activation.",regulation of neutrophil activation,biological_process
91137,GO:1902564,"Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.",negative regulation of neutrophil activation,biological_process
91138,GO:1902565,"Any process that activates or increases the frequency, rate or extent of neutrophil activation.",positive regulation of neutrophil activation,biological_process
91139,GO:1902566,"Any process that modulates the frequency, rate or extent of eosinophil activation.",regulation of eosinophil activation,biological_process
91140,GO:1902567,"Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.",negative regulation of eosinophil activation,biological_process
91141,GO:1902568,"Any process that activates or increases the frequency, rate or extent of eosinophil activation.",positive regulation of eosinophil activation,biological_process
91142,GO:1902570,"A process in which a protein is transported to, or maintained in, a location within a nucleolus.",protein localization to nucleolus,biological_process
91143,GO:1902572,"Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity.",negative regulation of serine-type peptidase activity,biological_process
91144,GO:1902576,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.",negative regulation of nuclear cell cycle DNA replication,biological_process
91145,GO:1902577,"A process in which a protein is transported to, or maintained in, a location within a medial cortical node.",protein localization to medial cortical node,biological_process
91146,GO:1902584,"Any process that activates or increases the frequency, rate or extent of response to water deprivation.",positive regulation of response to water deprivation,biological_process
91147,GO:1902599,The directed movement of sulfathiazole across a membrane.,sulfathiazole transmembrane transport,biological_process
91148,GO:1902600,The directed movement of a proton across a membrane.,proton transmembrane transport,biological_process
91149,GO:1902601,The directed movement of silver (Ag+) ions across a membrane.,silver ion transmembrane transport,biological_process
91150,GO:1902602,The directed movement of aluminium ions across a membrane.,aluminum ion transmembrane transport,biological_process
91151,GO:1902603,The directed movement of carnitine across a membrane.,carnitine transmembrane transport,biological_process
91152,GO:1902604,The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane.,p-aminobenzoyl-glutamate transmembrane transport,biological_process
91153,GO:1902605,"The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.",heterotrimeric G-protein complex assembly,biological_process
91154,GO:1902607,"Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.",negative regulation of large conductance calcium-activated potassium channel activity,biological_process
91155,GO:1902608,"Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.",positive regulation of large conductance calcium-activated potassium channel activity,biological_process
91156,GO:1902609,The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid.,(R)-2-hydroxy-alpha-linolenic acid biosynthetic process,biological_process
91157,GO:1902610,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.",response to N-phenylthiourea,biological_process
91158,GO:1902611,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.",cellular response to N-phenylthiourea,biological_process
91159,GO:1902612,"Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway.",regulation of anti-Mullerian hormone signaling pathway,biological_process
91160,GO:1902613,"Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.",negative regulation of anti-Mullerian hormone signaling pathway,biological_process
91161,GO:1902614,"Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.",positive regulation of anti-Mullerian hormone signaling pathway,biological_process
91162,GO:1902615,Any immune response that is involved in response to exogenous dsRNA.,immune response involved in response to exogenous dsRNA,biological_process
91163,GO:1902616,The process in which O-acyl-L-carnitine is transported across a membrane.,O-acyl-L-carnitine transmembrane transport,biological_process
91164,GO:1902617,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.",response to fluoride,biological_process
91165,GO:1902618,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.",cellular response to fluoride,biological_process
91166,GO:1902622,"Any process that modulates the frequency, rate or extent of neutrophil migration.",regulation of neutrophil migration,biological_process
91167,GO:1902623,"Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.",negative regulation of neutrophil migration,biological_process
91168,GO:1902624,"Any process that activates or increases the frequency, rate or extent of neutrophil migration.",positive regulation of neutrophil migration,biological_process
91169,GO:1902626,"The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.",assembly of large subunit precursor of preribosome,biological_process
91170,GO:1902627,"Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.",regulation of assembly of large subunit precursor of preribosome,biological_process
91171,GO:1902628,"Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome.",positive regulation of assembly of large subunit precursor of preribosome,biological_process
91172,GO:1902629,Any regulation of mRNA stability that is involved in cellular response to UV.,regulation of mRNA stability involved in cellular response to UV,biological_process
91173,GO:1902630,"Any process that modulates the frequency, rate or extent of membrane hyperpolarization.",regulation of membrane hyperpolarization,biological_process
91174,GO:1902631,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.",negative regulation of membrane hyperpolarization,biological_process
91175,GO:1902632,"Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.",positive regulation of membrane hyperpolarization,biological_process
91176,GO:1902633,"The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process",biological_process
91177,GO:1902634,"The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process",biological_process
91178,GO:1902635,"The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process",biological_process
91179,GO:1902636,A ciliary basal body that is part of a kinocilium.,kinociliary basal body,cellular_component
91180,GO:1902640,The chemical reactions and pathways resulting in the formation of propan-2-ol.,propan-2-ol biosynthetic process,biological_process
91181,GO:1902641,"Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.","regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process",biological_process
91182,GO:1902642,"Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.","negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process",biological_process
91183,GO:1902643,"Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.","positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process",biological_process
91184,GO:1902644,The chemical reactions and pathways involving tertiary alcohol.,tertiary alcohol metabolic process,biological_process
91185,GO:1902645,The chemical reactions and pathways resulting in the formation of tertiary alcohol.,tertiary alcohol biosynthetic process,biological_process
91186,GO:1902646,"Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.","regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process",biological_process
91187,GO:1902647,"Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.","negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process",biological_process
91188,GO:1902648,"Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.","positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process",biological_process
91189,GO:1902652,The chemical reactions and pathways involving secondary alcohol.,secondary alcohol metabolic process,biological_process
91190,GO:1902653,The chemical reactions and pathways resulting in the formation of secondary alcohol.,secondary alcohol biosynthetic process,biological_process
91191,GO:1902654,The chemical reactions and pathways involving aromatic primary alcohol.,aromatic primary alcohol metabolic process,biological_process
91192,GO:1902655,The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.,aromatic primary alcohol biosynthetic process,biological_process
91193,GO:1902656,The directed movement of calcium ion into a cytosol.,calcium ion import into cytosol,biological_process
91194,GO:1902657,"A process in which a protein is transported to, or maintained in, a location within a prospore membrane.",protein localization to prospore membrane,biological_process
91195,GO:1902659,"Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway.",regulation of glucose mediated signaling pathway,biological_process
91196,GO:1902660,"Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.",negative regulation of glucose mediated signaling pathway,biological_process
91197,GO:1902661,"Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.",positive regulation of glucose mediated signaling pathway,biological_process
91198,GO:1902662,"Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.",regulation of peptidyl-L-cysteine S-palmitoylation,biological_process
91199,GO:1902663,"Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.",negative regulation of peptidyl-L-cysteine S-palmitoylation,biological_process
91200,GO:1902664,"Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.",positive regulation of peptidyl-L-cysteine S-palmitoylation,biological_process
91201,GO:1902665,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus.",response to isobutanol,biological_process
91202,GO:1902667,"Any process that modulates the frequency, rate or extent of axon guidance.",regulation of axon guidance,biological_process
91203,GO:1902668,"Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance.",negative regulation of axon guidance,biological_process
91204,GO:1902669,"Any process that activates or increases the frequency, rate or extent of axon guidance.",positive regulation of axon guidance,biological_process
91205,GO:1902670,Binding to carbon dioxide.,carbon dioxide binding,molecular_function
91206,GO:1902671,Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).,left anterior basal body,cellular_component
91207,GO:1902672,Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage).,right anterior basal body,cellular_component
91208,GO:1902673,Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage).,left posteriolateral basal body,cellular_component
91209,GO:1902674,Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage).,right posteriolateral basal body,cellular_component
91210,GO:1902675,Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).,left ventral basal body,cellular_component
91211,GO:1902676,Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage).,right ventral basal body,cellular_component
91212,GO:1902677,Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage).,left caudal basal body,cellular_component
91213,GO:1902678,Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).,right caudal basal body,cellular_component
91214,GO:1902679,"Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.",negative regulation of RNA biosynthetic process,biological_process
91215,GO:1902680,"Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.",positive regulation of RNA biosynthetic process,biological_process
91216,GO:1902681,"Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.",regulation of replication fork arrest at rDNA repeats,biological_process
91217,GO:1902682,"A process in which a protein is transported to, or maintained in the pericentric heterochromatin.",protein localization to pericentric heterochromatin,biological_process
91218,GO:1902683,"Any process that modulates the frequency, rate or extent of receptor localization to synapse.",regulation of receptor localization to synapse,biological_process
91219,GO:1902684,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.",negative regulation of receptor localization to synapse,biological_process
91220,GO:1902685,"Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.",positive regulation of receptor localization to synapse,biological_process
91221,GO:1902686,The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.,mitochondrial outer membrane permeabilization involved in programmed cell death,biological_process
91222,GO:1902687,A protein complex which is capable of glucosidase activity.,glucosidase complex,cellular_component
91223,GO:1902688,"Any process that modulates the frequency, rate or extent of NAD metabolic process.",regulation of NAD metabolic process,biological_process
91224,GO:1902689,"Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.",negative regulation of NAD metabolic process,biological_process
91225,GO:1902690,"Any process that activates or increases the frequency, rate or extent of NAD metabolic process.",positive regulation of NAD metabolic process,biological_process
91226,GO:1902691,The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.,respiratory basal cell differentiation,biological_process
91227,GO:1902692,"Any process that modulates the frequency, rate or extent of neuroblast proliferation.",regulation of neuroblast proliferation,biological_process
91228,GO:1902693,A protein complex which is capable of superoxide dismutase activity.,superoxide dismutase complex,cellular_component
91229,GO:1902694,A protein complex which is capable of superoxide dismutase copper chaperone activity.,superoxide dismutase copper chaperone complex,cellular_component
91230,GO:1902695,A protein complex which is capable of metallochaperone activity.,metallochaperone complex,cellular_component
91231,GO:1902708,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.",response to plumbagin,biological_process
91232,GO:1902709,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.",cellular response to plumbagin,biological_process
91233,GO:1902710,"A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.",GABA receptor complex,cellular_component
91234,GO:1902711,"A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor).",GABA-A receptor complex,cellular_component
91235,GO:1902712,"A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2.",G protein-coupled GABA receptor complex,cellular_component
91236,GO:1902716,Any cell cortex that is part of a growing cell tip.,cell cortex of growing cell tip,cellular_component
91237,GO:1902721,"Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.",negative regulation of prolactin secretion,biological_process
91238,GO:1902722,"Any process that activates or increases the frequency, rate or extent of prolactin secretion.",positive regulation of prolactin secretion,biological_process
91239,GO:1902723,"Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.",negative regulation of skeletal muscle satellite cell proliferation,biological_process
91240,GO:1902724,"Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.",positive regulation of skeletal muscle satellite cell proliferation,biological_process
91241,GO:1902725,"Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.",negative regulation of satellite cell differentiation,biological_process
91242,GO:1902726,"Any process that activates or increases the frequency, rate or extent of satellite cell differentiation.",positive regulation of skeletal muscle satellite cell differentiation,biological_process
91243,GO:1902727,"Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.",negative regulation of growth factor dependent skeletal muscle satellite cell proliferation,biological_process
91244,GO:1902728,"Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.",positive regulation of growth factor dependent skeletal muscle satellite cell proliferation,biological_process
91245,GO:1902729,"Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",negative regulation of proteoglycan biosynthetic process,biological_process
91246,GO:1902730,"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.",positive regulation of proteoglycan biosynthetic process,biological_process
91247,GO:1902731,"Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.",negative regulation of chondrocyte proliferation,biological_process
91248,GO:1902732,"Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.",positive regulation of chondrocyte proliferation,biological_process
91249,GO:1902733,"Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.",regulation of growth plate cartilage chondrocyte differentiation,biological_process
91250,GO:1902734,"Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell.",regulation of receptor-mediated virion attachment to host cell,biological_process
91251,GO:1902735,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell.",negative regulation of receptor-mediated virion attachment to host cell,biological_process
91252,GO:1902736,"Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.",positive regulation of receptor-mediated virion attachment to host cell,biological_process
91253,GO:1902737,"A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.",dendritic filopodium,cellular_component
91254,GO:1902738,"Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.",regulation of chondrocyte differentiation involved in endochondral bone morphogenesis,biological_process
91255,GO:1902742,Any apoptotic process that is involved in anatomical structure development.,apoptotic process involved in development,biological_process
91256,GO:1902743,"Any process that modulates the frequency, rate or extent of lamellipodium organization.",regulation of lamellipodium organization,biological_process
91257,GO:1902744,"Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization.",negative regulation of lamellipodium organization,biological_process
91258,GO:1902745,"Any process that activates or increases the frequency, rate or extent of lamellipodium organization.",positive regulation of lamellipodium organization,biological_process
91259,GO:1902746,"Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.",regulation of lens fiber cell differentiation,biological_process
91260,GO:1902747,"Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.",negative regulation of lens fiber cell differentiation,biological_process
91261,GO:1902748,"Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.",positive regulation of lens fiber cell differentiation,biological_process
91262,GO:1902749,Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.,regulation of cell cycle G2/M phase transition,biological_process
91263,GO:1902750,Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.,negative regulation of cell cycle G2/M phase transition,biological_process
91264,GO:1902751,Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.,positive regulation of cell cycle G2/M phase transition,biological_process
91265,GO:1902752,"Any process that modulates the frequency, rate or extent of renal amino acid absorption.",regulation of renal amino acid absorption,biological_process
91266,GO:1902753,"Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption.",negative regulation of renal amino acid absorption,biological_process
91267,GO:1902754,"Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.",positive regulation of renal amino acid absorption,biological_process
91268,GO:1902756,The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).,sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process,biological_process
91269,GO:1902758,The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum.,bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process,biological_process
91270,GO:1902760,The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide.,Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process,biological_process
91271,GO:1902761,"Any process that activates or increases the frequency, rate or extent of chondrocyte development.",positive regulation of chondrocyte development,biological_process
91272,GO:1902762,"Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.",regulation of embryonic skeletal joint development,biological_process
91273,GO:1902763,"Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development.",negative regulation of embryonic skeletal joint development,biological_process
91274,GO:1902764,"Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.",positive regulation of embryonic skeletal joint development,biological_process
91275,GO:1902766,The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.,skeletal muscle satellite cell migration,biological_process
91276,GO:1902773,A protein complex which is capable of GTPase activator activity.,GTPase activator complex,cellular_component
91277,GO:1902774,The directed movement of substances from late endosome to lysosome.,late endosome to lysosome transport,biological_process
91278,GO:1902775,"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.",mitochondrial large ribosomal subunit assembly,biological_process
91279,GO:1902777,The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).,6-sulfoquinovose(1-) catabolic process,biological_process
91280,GO:1902778,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.",response to alkane,biological_process
91281,GO:1902779,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.",cellular response to alkane,biological_process
91282,GO:1902780,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.",response to nonane,biological_process
91283,GO:1902781,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.",cellular response to nonane,biological_process
91284,GO:1902782,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.",response to decane,biological_process
91285,GO:1902783,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.",cellular response to decane,biological_process
91286,GO:1902784,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.",response to undecane,biological_process
91287,GO:1902785,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.",cellular response to undecane,biological_process
91288,GO:1902786,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.",response to dodecane,biological_process
91289,GO:1902787,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.",cellular response to dodecane,biological_process
91290,GO:1902788,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.",response to isooctane,biological_process
91291,GO:1902789,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.",cellular response to isooctane,biological_process
91292,GO:1902791,The chemical reactions and pathways resulting in the formation of undecan-2-one.,undecan-2-one biosynthetic process,biological_process
91293,GO:1902792,A protein complex which is capable of pyrroline-5-carboxylate reductase activity.,pyrroline-5-carboxylate reductase complex,cellular_component
91294,GO:1902793,A protein complex which is capable of glutamate decarboxylase activity.,glutamate decarboxylase complex,cellular_component
91295,GO:1902794,"The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs.",siRNA-independent facultative heterochromatin formation,biological_process
91296,GO:1902795,"The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA.",siRNA-mediated facultative heterochromatin formation,biological_process
91297,GO:1902796,"Any process that modulates the frequency, rate or extent of snoRNA processing.",regulation of snoRNA processing,biological_process
91298,GO:1902797,"Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.",negative regulation of snoRNA processing,biological_process
91299,GO:1902798,"Any process that activates or increases the frequency, rate or extent of snoRNA processing.",positive regulation of snoRNA processing,biological_process
91300,GO:1902800,"Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.",positive regulation of phosphodiesterase I activity,biological_process
91301,GO:1902801,"Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly.",regulation of siRNA-independent facultative heterochromatin formation,biological_process
91302,GO:1902802,"Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation.",regulation of siRNA-mediated facultative heterochromatin formation,biological_process
91303,GO:1902803,"Any process that modulates the frequency, rate or extent of synaptic vesicle transport.",regulation of synaptic vesicle transport,biological_process
91304,GO:1902804,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport.",negative regulation of synaptic vesicle transport,biological_process
91305,GO:1902805,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.",positive regulation of synaptic vesicle transport,biological_process
91306,GO:1902806,Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.,regulation of cell cycle G1/S phase transition,biological_process
91307,GO:1902807,Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.,negative regulation of cell cycle G1/S phase transition,biological_process
91308,GO:1902808,Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.,positive regulation of cell cycle G1/S phase transition,biological_process
91309,GO:1902809,"Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.",regulation of skeletal muscle fiber differentiation,biological_process
91310,GO:1902810,"Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.",negative regulation of skeletal muscle fiber differentiation,biological_process
91311,GO:1902811,"Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.",positive regulation of skeletal muscle fiber differentiation,biological_process
91312,GO:1902815,"The directed movement of N,N'-diacetylchitobiose into a cell or organelle.","N,N'-diacetylchitobiose import",biological_process
91313,GO:1902816,"Any process that modulates the frequency, rate or extent of protein localization to microtubule.",regulation of protein localization to microtubule,biological_process
91314,GO:1902817,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.",negative regulation of protein localization to microtubule,biological_process
91315,GO:1902819,The chemical reactions and pathways resulting in the formation of ethyl acetate.,ethyl acetate biosynthetic process,biological_process
91316,GO:1902821,The chemical reactions and pathways resulting in the formation of 1-undecene.,1-undecene biosynthetic process,biological_process
91317,GO:1902822,"Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.",regulation of late endosome to lysosome transport,biological_process
91318,GO:1902823,"Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.",negative regulation of late endosome to lysosome transport,biological_process
91319,GO:1902824,"Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.",positive regulation of late endosome to lysosome transport,biological_process
91320,GO:1902829,"Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.",regulation of spinal cord association neuron differentiation,biological_process
91321,GO:1902830,"Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.",negative regulation of spinal cord association neuron differentiation,biological_process
91322,GO:1902831,"Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.",positive regulation of spinal cord association neuron differentiation,biological_process
91323,GO:1902832,"Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.",negative regulation of cell proliferation in dorsal spinal cord,biological_process
91324,GO:1902833,"Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.",positive regulation of cell proliferation in dorsal spinal cord,biological_process
91325,GO:1902834,"Any process that modulates the frequency, rate or extent of proline import into cell.",regulation of proline import across plasma membrane,biological_process
91326,GO:1902835,"Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell.",negative regulation of proline import across plasma membrane,biological_process
91327,GO:1902836,"Any process that activates or increases the frequency, rate or extent of proline import into cell.",positive regulation of proline import across plasma membrane,biological_process
91328,GO:1902838,"Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.",regulation of nuclear migration along microtubule,biological_process
91329,GO:1902839,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.",negative regulation of nuclear migration along microtubule,biological_process
91330,GO:1902840,"Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.",positive regulation of nuclear migration along microtubule,biological_process
91331,GO:1902841,"Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.",regulation of netrin-activated signaling pathway,biological_process
91332,GO:1902842,"Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.",negative regulation of netrin-activated signaling pathway,biological_process
91333,GO:1902843,"Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.",positive regulation of netrin-activated signaling pathway,biological_process
91334,GO:1902845,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.",negative regulation of mitotic spindle elongation,biological_process
91335,GO:1902846,"Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.",positive regulation of mitotic spindle elongation,biological_process
91336,GO:1902847,"Any process that modulates the frequency, rate or extent of neuronal signal transduction.",regulation of neuronal signal transduction,biological_process
91337,GO:1902848,"Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.",negative regulation of neuronal signal transduction,biological_process
91338,GO:1902849,"Any process that activates or increases the frequency, rate or extent of neuronal signal transduction.",positive regulation of neuronal signal transduction,biological_process
91339,GO:1902850,Any microtubule cytoskeleton organization that is involved in mitosis.,microtubule cytoskeleton organization involved in mitosis,biological_process
91340,GO:1902852,"Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.",regulation of nuclear migration during mitotic telophase,biological_process
91341,GO:1902853,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.",negative regulation of nuclear migration during mitotic telophase,biological_process
91342,GO:1902854,"Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.",positive regulation of nuclear migration during mitotic telophase,biological_process
91343,GO:1902855,"Any process that modulates the frequency, rate or extent of non-motile cilium assembly.",regulation of non-motile cilium assembly,biological_process
91344,GO:1902856,"Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.",negative regulation of non-motile cilium assembly,biological_process
91345,GO:1902857,"Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.",positive regulation of non-motile cilium assembly,biological_process
91346,GO:1902858,The chemical reactions and pathways involving propionyl-CoA.,propionyl-CoA metabolic process,biological_process
91347,GO:1902859,The chemical reactions and pathways resulting in the breakdown of propionyl-CoA.,propionyl-CoA catabolic process,biological_process
91348,GO:1902860,The chemical reactions and pathways resulting in the formation of propionyl-CoA.,propionyl-CoA biosynthetic process,biological_process
91349,GO:1902863,"Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.",regulation of embryonic camera-type eye development,biological_process
91350,GO:1902864,"Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.",negative regulation of embryonic camera-type eye development,biological_process
91351,GO:1902865,"Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.",positive regulation of embryonic camera-type eye development,biological_process
91352,GO:1902866,"Any process that modulates the frequency, rate or extent of retina development in camera-type eye.",regulation of retina development in camera-type eye,biological_process
91353,GO:1902867,"Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.",negative regulation of retina development in camera-type eye,biological_process
91354,GO:1902868,"Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.",positive regulation of retina development in camera-type eye,biological_process
91355,GO:1902869,"Any process that modulates the frequency, rate or extent of amacrine cell differentiation.",regulation of amacrine cell differentiation,biological_process
91356,GO:1902870,"Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.",negative regulation of amacrine cell differentiation,biological_process
91357,GO:1902871,"Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.",positive regulation of amacrine cell differentiation,biological_process
91358,GO:1902872,"Any process that modulates the frequency, rate or extent of horizontal cell localization.",regulation of horizontal cell localization,biological_process
91359,GO:1902873,"Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.",negative regulation of horizontal cell localization,biological_process
91360,GO:1902874,"Any process that activates or increases the frequency, rate or extent of horizontal cell localization.",positive regulation of horizontal cell localization,biological_process
91361,GO:1902875,"Any process that modulates the frequency, rate or extent of embryonic pattern specification.",regulation of embryonic pattern specification,biological_process
91362,GO:1902876,"Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.",negative regulation of embryonic pattern specification,biological_process
91363,GO:1902877,"Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.",positive regulation of embryonic pattern specification,biological_process
91364,GO:1902882,"Any process that modulates the frequency, rate or extent of response to oxidative stress.",regulation of response to oxidative stress,biological_process
91365,GO:1902883,"Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.",negative regulation of response to oxidative stress,biological_process
91366,GO:1902884,"Any process that activates or increases the frequency, rate or extent of response to oxidative stress.",positive regulation of response to oxidative stress,biological_process
91367,GO:1902888,"A process in which a protein is transported to, or maintained in, a location within an astral microtubule.",protein localization to astral microtubule,biological_process
91368,GO:1902889,"A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.",protein localization to spindle microtubule,biological_process
91369,GO:1902890,"Any process that modulates the frequency, rate or extent of root hair elongation.",regulation of root hair elongation,biological_process
91370,GO:1902891,"Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.",negative regulation of root hair elongation,biological_process
91371,GO:1902892,"Any process that activates or increases the frequency, rate or extent of root hair elongation.",positive regulation of root hair elongation,biological_process
91372,GO:1902893,"Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription.",regulation of miRNA transcription,biological_process
91373,GO:1902894,"Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription.",negative regulation of miRNA transcription,biological_process
91374,GO:1902895,"Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription.",positive regulation of miRNA transcription,biological_process
91375,GO:1902896,"The aggregation, arrangement and bonding together of a set of components to form a terminal web.",terminal web assembly,biological_process
91376,GO:1902897,"Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.",regulation of postsynaptic density protein 95 clustering,biological_process
91377,GO:1902898,The chemical reactions and pathways involving fatty acid methyl ester.,fatty acid methyl ester metabolic process,biological_process
91378,GO:1902899,The chemical reactions and pathways resulting in the formation of fatty acid methyl ester.,fatty acid methyl ester biosynthetic process,biological_process
91379,GO:1902900,"The aggregation, arrangement and bonding together of a set of components to form a gut granule.",gut granule assembly,biological_process
91380,GO:1902902,"Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.",negative regulation of autophagosome assembly,biological_process
91381,GO:1902903,"Any process that modulates the frequency, rate or extent of supramolecular fiber organization.",regulation of supramolecular fiber organization,biological_process
91382,GO:1902904,"Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.",negative regulation of supramolecular fiber organization,biological_process
91383,GO:1902905,"Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.",positive regulation of supramolecular fiber organization,biological_process
91384,GO:1902906,"The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.",proteasome storage granule assembly,biological_process
91385,GO:1902907,The disaggregation of a proteasome storage granule into its constituent components.,proteasome storage granule disassembly,biological_process
91386,GO:1902908,"Any process that modulates the frequency, rate or extent of melanosome transport.",regulation of melanosome transport,biological_process
91387,GO:1902909,"Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.",negative regulation of melanosome transport,biological_process
91388,GO:1902910,"Any process that activates or increases the frequency, rate or extent of melanosome transport.",positive regulation of melanosome transport,biological_process
91389,GO:1902911,A protein complex which is capable of protein kinase activity.,protein kinase complex,cellular_component
91390,GO:1902912,A protein complex which is capable of pyruvate kinase activity.,pyruvate kinase complex,cellular_component
91391,GO:1902913,"Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.",positive regulation of neuroepithelial cell differentiation,biological_process
91392,GO:1902914,"Any process that modulates the frequency, rate or extent of protein polyubiquitination.",regulation of protein polyubiquitination,biological_process
91393,GO:1902915,"Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.",negative regulation of protein polyubiquitination,biological_process
91394,GO:1902916,"Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.",positive regulation of protein polyubiquitination,biological_process
91395,GO:1902917,"Any process that activates or increases the frequency, rate or extent of mating projection assembly.",positive regulation of mating projection assembly,biological_process
91396,GO:1902919,The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).,poly(5-hydroxyvalerate) biosynthetic process,biological_process
91397,GO:1902921,The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).,poly(hydroxyvalerate) biosynthetic process,biological_process
91398,GO:1902923,The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).,poly(3-hydroxyvalerate) biosynthetic process,biological_process
91399,GO:1902927,The chemical reactions and pathways resulting in the breakdown of inulin.,inulin catabolic process,biological_process
91400,GO:1902928,The chemical reactions and pathways resulting in the formation of inulin.,inulin biosynthetic process,biological_process
91401,GO:1902929,Any plasma membrane part that is part of a growing cell tip.,plasma membrane of growing cell tip,cellular_component
91402,GO:1902930,"Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.",regulation of alcohol biosynthetic process,biological_process
91403,GO:1902931,"Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.",negative regulation of alcohol biosynthetic process,biological_process
91404,GO:1902932,"Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.",positive regulation of alcohol biosynthetic process,biological_process
91405,GO:1902934,The chemical reactions and pathways resulting in the formation of isopentenol.,isopentenol biosynthetic process,biological_process
91406,GO:1902935,"A process in which a protein is transported to, or maintained in, a location within a septin ring.",protein localization to septin ring,biological_process
91407,GO:1902936,Binding to phosphatidylinositol bisphosphate.,phosphatidylinositol bisphosphate binding,molecular_function
91408,GO:1902937,A protein complex which is capable of inward rectifier potassium channel activity.,inward rectifier potassium channel complex,cellular_component
91409,GO:1902943,"Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.",positive regulation of voltage-gated chloride channel activity,biological_process
91410,GO:1902945,Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.,metalloendopeptidase activity involved in amyloid precursor protein catabolic process,molecular_function
91411,GO:1902946,"A process in which a protein is transported to, or maintained in, a location within an early endosome.",protein localization to early endosome,biological_process
91412,GO:1902950,"Any process that modulates the frequency, rate or extent of dendritic spine maintenance.",regulation of dendritic spine maintenance,biological_process
91413,GO:1902951,"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.",negative regulation of dendritic spine maintenance,biological_process
91414,GO:1902952,"Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.",positive regulation of dendritic spine maintenance,biological_process
91415,GO:1902953,"Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.",positive regulation of ER to Golgi vesicle-mediated transport,biological_process
91416,GO:1902956,"Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.","regulation of mitochondrial electron transport, NADH to ubiquinone",biological_process
91417,GO:1902957,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.","negative regulation of mitochondrial electron transport, NADH to ubiquinone",biological_process
91418,GO:1902958,"Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.","positive regulation of mitochondrial electron transport, NADH to ubiquinone",biological_process
91419,GO:1902965,"Any process that modulates the frequency, rate or extent of protein localization to early endosome.",regulation of protein localization to early endosome,biological_process
91420,GO:1902966,"Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.",positive regulation of protein localization to early endosome,biological_process
91421,GO:1902967,"A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.",protein localization to mitotic spindle midzone,biological_process
91422,GO:1902969,Any nuclear DNA replication that is involved in a mitotic cell cycle.,mitotic DNA replication,biological_process
91423,GO:1902974,Any DNA replication initiation involved in meiotic cell cycle DNA replication.,meiotic DNA replication initiation,biological_process
91424,GO:1902975,Any DNA replication initiation involved in mitotic cell cycle DNA replication.,mitotic DNA replication initiation,biological_process
91425,GO:1902976,Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle.,premeiotic DNA replication preinitiation complex assembly,biological_process
91426,GO:1902977,Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle.,mitotic DNA replication preinitiation complex assembly,biological_process
91427,GO:1902978,Any DNA replication termination involved in meiotic cell cycle DNA replication.,premeiotic DNA replication termination,biological_process
91428,GO:1902979,Any DNA replication termination involved in mitotic cell cycle DNA replication.,mitotic DNA replication termination,biological_process
91429,GO:1902983,Any DNA strand elongation involved in mitotic cell cycle DNA replication.,DNA strand elongation involved in mitotic DNA replication,biological_process
91430,GO:1902985,Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication.,mitotic pre-replicative complex assembly,biological_process
91431,GO:1902986,"Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.",regulation of lysine biosynthetic process via aminoadipic acid,biological_process
91432,GO:1902988,"The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.",neurofibrillary tangle assembly,biological_process
91433,GO:1902989,Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle.,meiotic telomere maintenance via semi-conservative replication,biological_process
91434,GO:1902990,Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.,mitotic telomere maintenance via semi-conservative replication,biological_process
91435,GO:1902991,"Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.",regulation of amyloid precursor protein catabolic process,biological_process
91436,GO:1902992,"Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process.",negative regulation of amyloid precursor protein catabolic process,biological_process
91437,GO:1902993,"Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process.",positive regulation of amyloid precursor protein catabolic process,biological_process
91438,GO:1902994,"Any process that modulates the frequency, rate or extent of phospholipid efflux.",regulation of phospholipid efflux,biological_process
91439,GO:1902995,"Any process that activates or increases the frequency, rate or extent of phospholipid efflux.",positive regulation of phospholipid efflux,biological_process
91440,GO:1902996,"Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly.",regulation of neurofibrillary tangle assembly,biological_process
91441,GO:1902997,"Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.",negative regulation of neurofibrillary tangle assembly,biological_process
91442,GO:1902998,"Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.",positive regulation of neurofibrillary tangle assembly,biological_process
91443,GO:1902999,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux.",negative regulation of phospholipid efflux,biological_process
91444,GO:1903000,"Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.",regulation of lipid transport across blood-brain barrier,biological_process
91445,GO:1903001,"Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.",negative regulation of lipid transport across blood-brain barrier,biological_process
91446,GO:1903002,"Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.",positive regulation of lipid transport across blood-brain barrier,biological_process
91447,GO:1903003,"Any process that activates or increases the frequency, rate or extent of protein deubiquitination.",positive regulation of protein deubiquitination,biological_process
91448,GO:1903004,"Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination.",regulation of protein K63-linked deubiquitination,biological_process
91449,GO:1903005,"Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination.",negative regulation of protein K63-linked deubiquitination,biological_process
91450,GO:1903006,"Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.",positive regulation of protein K63-linked deubiquitination,biological_process
91451,GO:1903008,The disaggregation of an organelle into its constituent components.,organelle disassembly,biological_process
91452,GO:1903009,The disaggregation of a proteasome complex into its constituent components.,proteasome complex disassembly,biological_process
91453,GO:1903010,"Any process that modulates the frequency, rate or extent of bone development.",regulation of bone development,biological_process
91454,GO:1903011,"Any process that stops, prevents or reduces the frequency, rate or extent of bone development.",negative regulation of bone development,biological_process
91455,GO:1903012,"Any process that activates or increases the frequency, rate or extent of bone development.",positive regulation of bone development,biological_process
91456,GO:1903013,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.",response to differentiation-inducing factor 1,biological_process
91457,GO:1903014,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.",cellular response to differentiation-inducing factor 1,biological_process
91458,GO:1903017,"Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.",positive regulation of exo-alpha-sialidase activity,biological_process
91459,GO:1903018,"Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.",regulation of glycoprotein metabolic process,biological_process
91460,GO:1903019,"Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.",negative regulation of glycoprotein metabolic process,biological_process
91461,GO:1903020,"Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.",positive regulation of glycoprotein metabolic process,biological_process
91462,GO:1903023,"Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane.",regulation of ascospore-type prospore membrane formation,biological_process
91463,GO:1903024,"Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane.",positive regulation of ascospore-type prospore membrane formation,biological_process
91464,GO:1903025,"Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.",regulation of RNA polymerase II regulatory region sequence-specific DNA binding,biological_process
91465,GO:1903026,"Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.",negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding,biological_process
91466,GO:1903027,"Any process that modulates the frequency, rate or extent of opsonization.",regulation of opsonization,biological_process
91467,GO:1903028,"Any process that activates or increases the frequency, rate or extent of opsonization.",positive regulation of opsonization,biological_process
91468,GO:1903034,"Any process that modulates the frequency, rate or extent of response to wounding.",regulation of response to wounding,biological_process
91469,GO:1903035,"Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.",negative regulation of response to wounding,biological_process
91470,GO:1903036,"Any process that activates or increases the frequency, rate or extent of response to wounding.",positive regulation of response to wounding,biological_process
91471,GO:1903037,"Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.",regulation of leukocyte cell-cell adhesion,biological_process
91472,GO:1903038,"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.",negative regulation of leukocyte cell-cell adhesion,biological_process
91473,GO:1903039,"Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.",positive regulation of leukocyte cell-cell adhesion,biological_process
91474,GO:1903040,"The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.",exon-exon junction complex assembly,biological_process
91475,GO:1903041,"Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.",regulation of chondrocyte hypertrophy,biological_process
91476,GO:1903042,"Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.",negative regulation of chondrocyte hypertrophy,biological_process
91477,GO:1903043,"Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.",positive regulation of chondrocyte hypertrophy,biological_process
91478,GO:1903044,"A process in which a protein is transported to, or maintained in, a location within a membrane raft.",protein localization to membrane raft,biological_process
91479,GO:1903045,Any neural crest cell migration that is involved in sympathetic nervous system development.,neural crest cell migration involved in sympathetic nervous system development,biological_process
91480,GO:1903046,A process that is part of the meiotic cell cycle.,meiotic cell cycle process,biological_process
91481,GO:1903047,A process that is part of the mitotic cell cycle.,mitotic cell cycle process,biological_process
91482,GO:1903053,"Any process that modulates the frequency, rate or extent of extracellular matrix organization.",regulation of extracellular matrix organization,biological_process
91483,GO:1903054,"Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.",negative regulation of extracellular matrix organization,biological_process
91484,GO:1903055,"Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.",positive regulation of extracellular matrix organization,biological_process
91485,GO:1903056,"Any process that modulates the frequency, rate or extent of melanosome organization.",regulation of melanosome organization,biological_process
91486,GO:1903057,"Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.",negative regulation of melanosome organization,biological_process
91487,GO:1903058,"Any process that activates or increases the frequency, rate or extent of melanosome organization.",positive regulation of melanosome organization,biological_process
91488,GO:1903059,"Any process that modulates the frequency, rate or extent of protein lipidation.",regulation of protein lipidation,biological_process
91489,GO:1903060,"Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation.",negative regulation of protein lipidation,biological_process
91490,GO:1903061,"Any process that activates or increases the frequency, rate or extent of protein lipidation.",positive regulation of protein lipidation,biological_process
91491,GO:1903062,"Any process that modulates the frequency, rate or extent of reverse cholesterol transport.",regulation of reverse cholesterol transport,biological_process
91492,GO:1903063,"Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.",negative regulation of reverse cholesterol transport,biological_process
91493,GO:1903064,"Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport.",positive regulation of reverse cholesterol transport,biological_process
91494,GO:1903066,"Any process that modulates the frequency, rate or extent of protein localization to cell tip.",regulation of protein localization to cell tip,biological_process
91495,GO:1903067,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.",negative regulation of protein localization to cell tip,biological_process
91496,GO:1903068,"Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.",positive regulation of protein localization to cell tip,biological_process
91497,GO:1903072,"Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.",regulation of death-inducing signaling complex assembly,biological_process
91498,GO:1903073,"Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.",negative regulation of death-inducing signaling complex assembly,biological_process
91499,GO:1903074,"The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.",TRAIL death-inducing signaling complex assembly,biological_process
91500,GO:1903075,"The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol.",pyridoxine import across plasma membrane,biological_process
91501,GO:1903076,"Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.",regulation of protein localization to plasma membrane,biological_process
91502,GO:1903077,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.",negative regulation of protein localization to plasma membrane,biological_process
91503,GO:1903078,"Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.",positive regulation of protein localization to plasma membrane,biological_process
91504,GO:1903080,"Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.",regulation of C-C chemokine receptor CCR7 signaling pathway,biological_process
91505,GO:1903081,"Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.",negative regulation of C-C chemokine receptor CCR7 signaling pathway,biological_process
91506,GO:1903082,"Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.",positive regulation of C-C chemokine receptor CCR7 signaling pathway,biological_process
91507,GO:1903083,"A process in which a protein is transported to, or maintained in, a location within a condensed chromosome.",protein localization to condensed chromosome,biological_process
91508,GO:1903084,"A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome.",protein localization to condensed nuclear chromosome,biological_process
91509,GO:1903085,"Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.",regulation of sinapate ester biosynthetic process,biological_process
91510,GO:1903086,"Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.",negative regulation of sinapate ester biosynthetic process,biological_process
91511,GO:1903087,Any spindle pole body duplication that is involved in the mitotic cell cycle.,mitotic spindle pole body duplication,biological_process
91512,GO:1903088,The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane.,5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport,biological_process
91513,GO:1903089,Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.,5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity,molecular_function
91514,GO:1903090,The process in which pyridoxal is transported across a membrane.,pyridoxal transmembrane transport,biological_process
91515,GO:1903091,The process in which pyridoxamine is transported across a membrane.,pyridoxamine transmembrane transport,biological_process
91516,GO:1903092,The process in which pyridoxine is transported across a membrane.,pyridoxine transmembrane transport,biological_process
91517,GO:1903093,"Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination.",regulation of protein K48-linked deubiquitination,biological_process
91518,GO:1903094,"Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.",negative regulation of protein K48-linked deubiquitination,biological_process
91519,GO:1903095,A protein complex which is capable of ribonuclease III activity.,ribonuclease III complex,cellular_component
91520,GO:1903096,"A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone.",protein localization to meiotic spindle midzone,biological_process
91521,GO:1903100,"The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process",biological_process
91522,GO:1903101,"The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process",biological_process
91523,GO:1903102,"The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.","1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process",biological_process
91524,GO:1903103,A protein complex which is capable of potassium:proton antiporter activity.,potassium:proton antiporter complex,cellular_component
91525,GO:1903108,"Any process that modulates the frequency, rate or extent of transcription occurring in the mitochondrion.",regulation of mitochondrial transcription,biological_process
91526,GO:1903109,"Any process that activates or increases the frequency, rate or extent of transcription occurring in the mitochondrion.",positive regulation of mitochondrial transcription,biological_process
91527,GO:1903110,"Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.",regulation of single-strand break repair via homologous recombination,biological_process
91528,GO:1903111,"Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.",negative regulation of single-strand break repair via homologous recombination,biological_process
91529,GO:1903112,"Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.",positive regulation of single-strand break repair via homologous recombination,biological_process
91530,GO:1903113,A protein complex which is capable of copper ion transmembrane transporter activity.,copper ion transmembrane transporter complex,cellular_component
91531,GO:1903114,A protein complex which is capable of silver ion transmembrane transporter activity.,silver ion transmembrane transporter complex,cellular_component
91532,GO:1903115,"Any process that modulates the frequency, rate or extent of actin filament-based movement.",regulation of actin filament-based movement,biological_process
91533,GO:1903116,"Any process that activates or increases the frequency, rate or extent of actin filament-based movement.",positive regulation of actin filament-based movement,biological_process
91534,GO:1903119,"A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.",protein localization to actin cytoskeleton,biological_process
91535,GO:1903120,"A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.",protein localization to actin filament bundle,biological_process
91536,GO:1903121,"Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.",regulation of TRAIL-activated apoptotic signaling pathway,biological_process
91537,GO:1903122,"Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.",negative regulation of TRAIL-activated apoptotic signaling pathway,biological_process
91538,GO:1903126,"Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.",negative regulation of centriole-centriole cohesion,biological_process
91539,GO:1903127,"Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.",positive regulation of centriole-centriole cohesion,biological_process
91540,GO:1903131,The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.,mononuclear cell differentiation,biological_process
91541,GO:1903132,"Any process that modulates the frequency, rate or extent of tube lumen cavitation.",regulation of tube lumen cavitation,biological_process
91542,GO:1903133,"Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation.",negative regulation of tube lumen cavitation,biological_process
91543,GO:1903135,"Binding to a cupric ion, copper(2+).",cupric ion binding,molecular_function
91544,GO:1903136,"Binding to a cuprous ion, copper(1+).",cuprous ion binding,molecular_function
91545,GO:1903137,"Any process that modulates the frequency, rate or extent of a cell integrity MAPK cascade.",regulation of cell integrity MAPK cascade,biological_process
91546,GO:1903138,"Any process that stops, prevents or reduces the frequency, rate or extent of a cell integrity MAPK cascade.",negative regulation of cell integrity MAPK cascade,biological_process
91547,GO:1903139,"Any process that activates or increases the frequency, rate or extent of a cell integrity MAPK cascade.",positive regulation of cell integrity MAPK cascade,biological_process
91548,GO:1903140,"Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.",regulation of establishment of endothelial barrier,biological_process
91549,GO:1903141,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.",negative regulation of establishment of endothelial barrier,biological_process
91550,GO:1903142,"Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.",positive regulation of establishment of endothelial barrier,biological_process
91551,GO:1903143,"A transmembrane, G protein-coupled signaling receptor complex which is capable of adrenomedullin receptor activity.",adrenomedullin receptor complex,cellular_component
91552,GO:1903144,Any actin filament that is part of a actomyosin contractile ring.,actomyosin contractile ring actin filament,cellular_component
91553,GO:1903145,Any actin filament that is part of a cell cortex of cell tip.,actin filament of cell cortex of cell tip,cellular_component
91554,GO:1903146,"Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.",regulation of autophagy of mitochondrion,biological_process
91555,GO:1903147,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.",negative regulation of autophagy of mitochondrion,biological_process
91556,GO:1903165,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.",response to polycyclic arene,biological_process
91557,GO:1903166,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.",cellular response to polycyclic arene,biological_process
91558,GO:1903169,"Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.",regulation of calcium ion transmembrane transport,biological_process
91559,GO:1903170,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.",negative regulation of calcium ion transmembrane transport,biological_process
91560,GO:1903173,The chemical reactions and pathways involving fatty alcohol.,fatty alcohol metabolic process,biological_process
91561,GO:1903174,The chemical reactions and pathways resulting in the breakdown of fatty alcohol.,fatty alcohol catabolic process,biological_process
91562,GO:1903175,The chemical reactions and pathways resulting in the formation of fatty alcohol.,fatty alcohol biosynthetic process,biological_process
91563,GO:1903179,"Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.",regulation of dopamine biosynthetic process,biological_process
91564,GO:1903180,"Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.",negative regulation of dopamine biosynthetic process,biological_process
91565,GO:1903181,"Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.",positive regulation of dopamine biosynthetic process,biological_process
91566,GO:1903186,"Any process that modulates the frequency, rate or extent of vitellogenesis.",regulation of vitellogenesis,biological_process
91567,GO:1903187,"Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.",negative regulation of vitellogenesis,biological_process
91568,GO:1903188,"Any process that activates or increases the frequency, rate or extent of vitellogenesis.",positive regulation of vitellogenesis,biological_process
91569,GO:1903189,The chemical reactions and pathways involving glyoxal.,glyoxal metabolic process,biological_process
91570,GO:1903190,The chemical reactions and pathways resulting in the breakdown of glyoxal.,glyoxal catabolic process,biological_process
91571,GO:1903191,The chemical reactions and pathways resulting in the formation of glyoxal.,glyoxal biosynthetic process,biological_process
91572,GO:1903193,The chemical reactions and pathways resulting in the formation of sesquarterpene.,sesquarterpene biosynthetic process,biological_process
91573,GO:1903210,Any apoptotic process in a glomerular visceral epithelial cell.,podocyte apoptotic process,biological_process
91574,GO:1903213,"A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin.",protein localization to subtelomeric heterochromatin,biological_process
91575,GO:1903221,"Any process that modulates the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences.",regulation of mitotic recombination-dependent replication fork processing,biological_process
91576,GO:1903222,The process in which quinolinic acid is transported across a membrane.,quinolinic acid transmembrane transport,biological_process
91577,GO:1903224,"Any process that modulates the frequency, rate or extent of endodermal cell differentiation.",regulation of endodermal cell differentiation,biological_process
91578,GO:1903225,"Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.",negative regulation of endodermal cell differentiation,biological_process
91579,GO:1903226,"Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.",positive regulation of endodermal cell differentiation,biological_process
91580,GO:1903228,The chemical reactions and pathways resulting in the breakdown of xanthosine.,xanthosine catabolic process,biological_process
91581,GO:1903229,The chemical reactions and pathways resulting in the formation of xanthosine.,xanthosine biosynthetic process,biological_process
91582,GO:1903231,A post-transcriptional repressor activity that acts by base-pairing with an mRNA to prevent gene expression. The binding can result in targeting the mRNA for degradation or interfering with mRNA translation resulting in post-transcriptional gene silencing.,mRNA base-pairing post-transcriptional repressor activity,molecular_function
91583,GO:1903232,"The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.",melanosome assembly,biological_process
91584,GO:1903233,"Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.",regulation of calcium ion-dependent exocytosis of neurotransmitter,biological_process
91585,GO:1903234,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.",negative regulation of calcium ion-dependent exocytosis of neurotransmitter,biological_process
91586,GO:1903235,"Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.",positive regulation of calcium ion-dependent exocytosis of neurotransmitter,biological_process
91587,GO:1903236,"Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling.",regulation of leukocyte tethering or rolling,biological_process
91588,GO:1903237,"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.",negative regulation of leukocyte tethering or rolling,biological_process
91589,GO:1903238,"Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.",positive regulation of leukocyte tethering or rolling,biological_process
91590,GO:1903241,"The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.",U2-type prespliceosome assembly,biological_process
91591,GO:1903242,"Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.",regulation of cardiac muscle hypertrophy in response to stress,biological_process
91592,GO:1903243,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.",negative regulation of cardiac muscle hypertrophy in response to stress,biological_process
91593,GO:1903244,"Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.",positive regulation of cardiac muscle hypertrophy in response to stress,biological_process
91594,GO:1903248,"Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.",regulation of citrulline biosynthetic process,biological_process
91595,GO:1903249,"Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.",negative regulation of citrulline biosynthetic process,biological_process
91596,GO:1903250,"Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.",positive regulation of citrulline biosynthetic process,biological_process
91597,GO:1903251,The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.,multi-ciliated epithelial cell differentiation,biological_process
91598,GO:1903257,The chemical reactions and pathways resulting in the formation of selenoneine.,selenoneine biosynthetic process,biological_process
91599,GO:1903259,The disaggregation of an exon-exon junction complex into its constituent components.,exon-exon junction complex disassembly,biological_process
91600,GO:1903260,"A process in which a protein is transported to, or maintained in, a location within a mating projection tip.",protein localization to mating projection tip,biological_process
91601,GO:1903265,"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.",positive regulation of tumor necrosis factor-mediated signaling pathway,biological_process
91602,GO:1903266,"Any process that modulates the frequency, rate or extent of ornithine catabolic process.",regulation of ornithine catabolic process,biological_process
91603,GO:1903267,"Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.",negative regulation of ornithine catabolic process,biological_process
91604,GO:1903268,"Any process that activates or increases the frequency, rate or extent of ornithine catabolic process.",positive regulation of ornithine catabolic process,biological_process
91605,GO:1903269,A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity.,ornithine carbamoyltransferase inhibitor complex,cellular_component
91606,GO:1903270,"Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.",regulation of cytoplasmic translational elongation through polyproline stretches,biological_process
91607,GO:1903271,"Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.",negative regulation of cytoplasmic translational elongation through polyproline stretches,biological_process
91608,GO:1903272,"Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.",positive regulation of cytoplasmic translational elongation through polyproline stretches,biological_process
91609,GO:1903276,"Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.",regulation of sodium ion export across plasma membrane,biological_process
91610,GO:1903277,"Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.",negative regulation of sodium ion export across plasma membrane,biological_process
91611,GO:1903278,"Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.",positive regulation of sodium ion export across plasma membrane,biological_process
91612,GO:1903285,"Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.",positive regulation of hydrogen peroxide catabolic process,biological_process
91613,GO:1903286,"Any process that modulates the frequency, rate or extent of potassium ion import.",regulation of potassium ion import,biological_process
91614,GO:1903287,"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.",negative regulation of potassium ion import across plasma membrane,biological_process
91615,GO:1903288,"Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.",positive regulation of potassium ion import across plasma membrane,biological_process
91616,GO:1903292,"A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.",protein localization to Golgi membrane,biological_process
91617,GO:1903293,A protein complex which is capable of phosphatase activity.,phosphatase complex,cellular_component
91618,GO:1903294,"Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.","regulation of glutamate secretion, neurotransmission",biological_process
91619,GO:1903295,"Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.","negative regulation of glutamate secretion, neurotransmission",biological_process
91620,GO:1903296,"Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.","positive regulation of glutamate secretion, neurotransmission",biological_process
91621,GO:1903297,"Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.",regulation of hypoxia-induced intrinsic apoptotic signaling pathway,biological_process
91622,GO:1903298,"Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.",negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway,biological_process
91623,GO:1903301,"Any process that activates or increases the frequency, rate or extent of hexokinase activity.",positive regulation of hexokinase activity,biological_process
91624,GO:1903302,"Any process that modulates the frequency, rate or extent of pyruvate kinase activity.",regulation of pyruvate kinase activity,biological_process
91625,GO:1903305,"Any process that modulates the frequency, rate or extent of regulated secretory pathway.",regulation of regulated secretory pathway,biological_process
91626,GO:1903306,"Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.",negative regulation of regulated secretory pathway,biological_process
91627,GO:1903307,"Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.",positive regulation of regulated secretory pathway,biological_process
91628,GO:1903311,"Any process that modulates the frequency, rate or extent of mRNA metabolic process.",regulation of mRNA metabolic process,biological_process
91629,GO:1903312,"Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.",negative regulation of mRNA metabolic process,biological_process
91630,GO:1903313,"Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.",positive regulation of mRNA metabolic process,biological_process
91631,GO:1903317,"Any process that modulates the frequency, rate or extent of protein maturation.",regulation of protein maturation,biological_process
91632,GO:1903318,"Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.",negative regulation of protein maturation,biological_process
91633,GO:1903319,"Any process that activates or increases the frequency, rate or extent of protein maturation.",positive regulation of protein maturation,biological_process
91634,GO:1903320,"Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal.",regulation of protein modification by small protein conjugation or removal,biological_process
91635,GO:1903321,"Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal.",negative regulation of protein modification by small protein conjugation or removal,biological_process
91636,GO:1903322,"Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal.",positive regulation of protein modification by small protein conjugation or removal,biological_process
91637,GO:1903323,"Any process that modulates the frequency, rate or extent of snoRNA metabolic process.",regulation of snoRNA metabolic process,biological_process
91638,GO:1903324,"Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.",negative regulation of snoRNA metabolic process,biological_process
91639,GO:1903325,"Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.",positive regulation of snoRNA metabolic process,biological_process
91640,GO:1903326,"Any process that modulates the frequency, rate or extent of tRNA metabolic process.",regulation of tRNA metabolic process,biological_process
91641,GO:1903327,"Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.",negative regulation of tRNA metabolic process,biological_process
91642,GO:1903328,"Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.",positive regulation of tRNA metabolic process,biological_process
91643,GO:1903329,"Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly.",regulation of iron-sulfur cluster assembly,biological_process
91644,GO:1903330,"Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.",negative regulation of iron-sulfur cluster assembly,biological_process
91645,GO:1903331,"Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.",positive regulation of iron-sulfur cluster assembly,biological_process
91646,GO:1903332,"Any process that modulates the frequency, rate or extent of protein folding.",regulation of protein folding,biological_process
91647,GO:1903333,"Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.",negative regulation of protein folding,biological_process
91648,GO:1903334,"Any process that activates or increases the frequency, rate or extent of protein folding.",positive regulation of protein folding,biological_process
91649,GO:1903335,"Any process that modulates the frequency, rate or extent of vacuolar transport.",regulation of vacuolar transport,biological_process
91650,GO:1903336,"Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.",negative regulation of vacuolar transport,biological_process
91651,GO:1903337,"Any process that activates or increases the frequency, rate or extent of vacuolar transport.",positive regulation of vacuolar transport,biological_process
91652,GO:1903338,"Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.",regulation of cell wall organization or biogenesis,biological_process
91653,GO:1903339,"Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.",negative regulation of cell wall organization or biogenesis,biological_process
91654,GO:1903340,"Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.",positive regulation of cell wall organization or biogenesis,biological_process
91655,GO:1903341,"Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.",regulation of meiotic DNA double-strand break formation,biological_process
91656,GO:1903342,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.",negative regulation of meiotic DNA double-strand break formation,biological_process
91657,GO:1903343,"Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.",positive regulation of meiotic DNA double-strand break formation,biological_process
91658,GO:1903344,"Any process that modulates the frequency, rate or extent of protein polyglycylation.",regulation of protein polyglycylation,biological_process
91659,GO:1903345,"Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation.",negative regulation of protein polyglycylation,biological_process
91660,GO:1903346,"Any process that activates or increases the frequency, rate or extent of protein polyglycylation.",positive regulation of protein polyglycylation,biological_process
91661,GO:1903347,"Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.",negative regulation of bicellular tight junction assembly,biological_process
91662,GO:1903348,"Any process that activates or increases the frequency, rate or extent of tight junction assembly.",positive regulation of bicellular tight junction assembly,biological_process
91663,GO:1903349,Any membrane that is part of an omegasome.,omegasome membrane,cellular_component
91664,GO:1903350,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.",response to dopamine,biological_process
91665,GO:1903351,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.",cellular response to dopamine,biological_process
91666,GO:1903352,The directed movement of L-ornithine across a membrane.,L-ornithine transmembrane transport,biological_process
91667,GO:1903353,"Any process that modulates the frequency, rate or extent of nucleus organization.",regulation of nucleus organization,biological_process
91668,GO:1903354,"Any process that modulates the frequency, rate or extent of distal tip cell migration.",regulation of distal tip cell migration,biological_process
91669,GO:1903355,"Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.",negative regulation of distal tip cell migration,biological_process
91670,GO:1903356,"Any process that activates or increases the frequency, rate or extent of distal tip cell migration.",positive regulation of distal tip cell migration,biological_process
91671,GO:1903357,"Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter.",regulation of transcription initiation by RNA polymerase I,biological_process
91672,GO:1903358,"Any process that modulates the frequency, rate or extent of Golgi organization.",regulation of Golgi organization,biological_process
91673,GO:1903359,"The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node.",lateral cortical node assembly,biological_process
91674,GO:1903360,"A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.",protein localization to lateral cortical node,biological_process
91675,GO:1903361,"Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane.",protein localization to basolateral plasma membrane,biological_process
91676,GO:1903365,"Any process that modulates the frequency, rate or extent of fear response.",regulation of fear response,biological_process
91677,GO:1903366,"Any process that stops, prevents or reduces the frequency, rate or extent of fear response.",negative regulation of fear response,biological_process
91678,GO:1903367,"Any process that activates or increases the frequency, rate or extent of fear response.",positive regulation of fear response,biological_process
91679,GO:1903368,"Any process that modulates the frequency, rate or extent of foraging behavior.",regulation of foraging behavior,biological_process
91680,GO:1903369,"Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior.",negative regulation of foraging behavior,biological_process
91681,GO:1903370,"Any process that activates or increases the frequency, rate or extent of foraging behavior.",positive regulation of foraging behavior,biological_process
91682,GO:1903371,"Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization.",regulation of endoplasmic reticulum tubular network organization,biological_process
91683,GO:1903372,"Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization.",negative regulation of endoplasmic reticulum tubular network organization,biological_process
91684,GO:1903373,"Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.",positive regulation of endoplasmic reticulum tubular network organization,biological_process
91685,GO:1903375,"The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.",facioacoustic ganglion development,biological_process
91686,GO:1903376,"Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.",regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway,biological_process
91687,GO:1903377,"Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.",negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway,biological_process
91688,GO:1903378,"Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.",positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway,biological_process
91689,GO:1903379,"Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.",regulation of mitotic chromosome condensation,biological_process
91690,GO:1903380,"Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.",positive regulation of mitotic chromosome condensation,biological_process
91691,GO:1903381,"Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.",regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway,biological_process
91692,GO:1903382,"Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.",negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway,biological_process
91693,GO:1903383,"Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.",regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway,biological_process
91694,GO:1903384,"Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.",negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway,biological_process
91695,GO:1903385,"Any process that modulates the frequency, rate or extent of homophilic cell adhesion.",regulation of homophilic cell adhesion,biological_process
91696,GO:1903386,"Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion.",negative regulation of homophilic cell adhesion,biological_process
91697,GO:1903387,"Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.",positive regulation of homophilic cell adhesion,biological_process
91698,GO:1903388,"Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating.",regulation of synaptic vesicle uncoating,biological_process
91699,GO:1903389,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.",negative regulation of synaptic vesicle uncoating,biological_process
91700,GO:1903390,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.",positive regulation of synaptic vesicle uncoating,biological_process
91701,GO:1903391,"Any process that modulates the frequency, rate or extent of adherens junction organization.",regulation of adherens junction organization,biological_process
91702,GO:1903392,"Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.",negative regulation of adherens junction organization,biological_process
91703,GO:1903393,"Any process that activates or increases the frequency, rate or extent of adherens junction organization.",positive regulation of adherens junction organization,biological_process
91704,GO:1903394,Any protein localization to kinetochore that is involved in kinetochore assembly.,protein localization to kinetochore involved in kinetochore assembly,biological_process
91705,GO:1903395,"Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis.",regulation of secondary cell septum biogenesis,biological_process
91706,GO:1903396,"Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.",negative regulation of secondary cell septum biogenesis,biological_process
91707,GO:1903397,"Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.",positive regulation of secondary cell septum biogenesis,biological_process
91708,GO:1903401,The directed movement of L-lysine across a membrane.,L-lysine transmembrane transport,biological_process
91709,GO:1903402,"Any process that modulates the frequency, rate or extent of renal phosphate excretion.",regulation of renal phosphate excretion,biological_process
91710,GO:1903403,"Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.",negative regulation of renal phosphate excretion,biological_process
91711,GO:1903404,"Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.",positive regulation of renal phosphate excretion,biological_process
91712,GO:1903405,"A process in which a protein is transported to, or maintained in, a location within a nuclear body.",protein localization to nuclear body,biological_process
91713,GO:1903406,"Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.",regulation of P-type sodium:potassium-exchanging transporter activity,biological_process
91714,GO:1903407,"Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.",negative regulation of P-type sodium:potassium-exchanging transporter activity,biological_process
91715,GO:1903408,"Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.",positive regulation of P-type sodium:potassium-exchanging transporter activity,biological_process
91716,GO:1903409,"The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.",reactive oxygen species biosynthetic process,biological_process
91717,GO:1903412,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.",response to bile acid,biological_process
91718,GO:1903413,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.",cellular response to bile acid,biological_process
91719,GO:1903415,The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.,flavonoid transport from endoplasmic reticulum to plant-type vacuole,biological_process
91720,GO:1903416,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.",response to glycoside,biological_process
91721,GO:1903418,"A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip.",protein localization to plasma membrane of cell tip,biological_process
91722,GO:1903419,"A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.",protein localization to cortical endoplasmic reticulum,biological_process
91723,GO:1903420,"A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.",protein localization to endoplasmic reticulum tubular network,biological_process
91724,GO:1903421,"Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.",regulation of synaptic vesicle recycling,biological_process
91725,GO:1903422,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.",negative regulation of synaptic vesicle recycling,biological_process
91726,GO:1903423,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.",positive regulation of synaptic vesicle recycling,biological_process
91727,GO:1903424,The process in which fluoride is transported across a membrane.,fluoride transmembrane transport,biological_process
91728,GO:1903425,Enables the transfer of fluoride from one side of a membrane to the other.,fluoride transmembrane transporter activity,molecular_function
91729,GO:1903426,"Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.",regulation of reactive oxygen species biosynthetic process,biological_process
91730,GO:1903427,"Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.",negative regulation of reactive oxygen species biosynthetic process,biological_process
91731,GO:1903428,"Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.",positive regulation of reactive oxygen species biosynthetic process,biological_process
91732,GO:1903429,"Any process that modulates the frequency, rate or extent of cell maturation.",regulation of cell maturation,biological_process
91733,GO:1903430,"Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.",negative regulation of cell maturation,biological_process
91734,GO:1903431,"Any process that activates or increases the frequency, rate or extent of cell maturation.",positive regulation of cell maturation,biological_process
91735,GO:1903432,"Any process that modulates the frequency, rate or extent of TORC1 signaling.",regulation of TORC1 signaling,biological_process
91736,GO:1903433,"Any process that modulates the frequency, rate or extent of constitutive secretory pathway.",regulation of constitutive secretory pathway,biological_process
91737,GO:1903434,"Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway.",negative regulation of constitutive secretory pathway,biological_process
91738,GO:1903435,"Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.",positive regulation of constitutive secretory pathway,biological_process
91739,GO:1903436,"Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.",regulation of mitotic cytokinetic process,biological_process
91740,GO:1903437,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.",negative regulation of mitotic cytokinetic process,biological_process
91741,GO:1903438,"Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.",positive regulation of mitotic cytokinetic process,biological_process
91742,GO:1903439,"A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.",calcitonin family receptor complex,cellular_component
91743,GO:1903440,A protein complex which is capable of amylin receptor activity.,amylin receptor complex,cellular_component
91744,GO:1903441,"A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.",protein localization to ciliary membrane,biological_process
91745,GO:1903442,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.",response to lipoic acid,biological_process
91746,GO:1903443,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.",cellular response to lipoic acid,biological_process
91747,GO:1903444,"Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.",negative regulation of brown fat cell differentiation,biological_process
91748,GO:1903445,The directed movement of protein from ciliary membrane to plasma membrane.,protein transport from ciliary membrane to plasma membrane,biological_process
91749,GO:1903447,The chemical reactions and pathways resulting in the breakdown of geraniol.,geraniol catabolic process,biological_process
91750,GO:1903448,The chemical reactions and pathways resulting in the formation of geraniol.,geraniol biosynthetic process,biological_process
91751,GO:1903449,"The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione.","androst-4-ene-3,17-dione biosynthetic process",biological_process
91752,GO:1903450,"Any process that modulates the frequency, rate or extent of G1 to G0 transition.",regulation of G1 to G0 transition,biological_process
91753,GO:1903451,"Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.",negative regulation of G1 to G0 transition,biological_process
91754,GO:1903452,"Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.",positive regulation of G1 to G0 transition,biological_process
91755,GO:1903454,"Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.","regulation of androst-4-ene-3,17-dione biosynthetic process",biological_process
91756,GO:1903455,"Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.","negative regulation of androst-4-ene-3,17-dione biosynthetic process",biological_process
91757,GO:1903456,"Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.","positive regulation of androst-4-ene-3,17-dione biosynthetic process",biological_process
91758,GO:1903457,The chemical reactions and pathways resulting in the breakdown of lactate.,lactate catabolic process,biological_process
91759,GO:1903459,Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.,mitotic DNA replication lagging strand elongation,biological_process
91760,GO:1903460,Any leading strand elongation that is involved in mitotic cell cycle DNA replication.,mitotic DNA replication leading strand elongation,biological_process
91761,GO:1903461,"Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.",Okazaki fragment processing involved in mitotic DNA replication,biological_process
91762,GO:1903463,"Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.",regulation of mitotic cell cycle DNA replication,biological_process
91763,GO:1903464,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.",negative regulation of mitotic cell cycle DNA replication,biological_process
91764,GO:1903465,"Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.",positive regulation of mitotic cell cycle DNA replication,biological_process
91765,GO:1903466,"Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.",regulation of mitotic DNA replication initiation,biological_process
91766,GO:1903467,"Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.",negative regulation of mitotic DNA replication initiation,biological_process
91767,GO:1903468,"Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.",positive regulation of DNA replication initiation,biological_process
91768,GO:1903469,"Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication.",removal of RNA primer involved in mitotic DNA replication,biological_process
91769,GO:1903471,"Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.",regulation of mitotic actomyosin contractile ring contraction,biological_process
91770,GO:1903472,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.",negative regulation of mitotic actomyosin contractile ring contraction,biological_process
91771,GO:1903473,"Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.",positive regulation of mitotic actomyosin contractile ring contraction,biological_process
91772,GO:1903475,Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.,mitotic actomyosin contractile ring assembly,biological_process
91773,GO:1903476,Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.,protein localization to cell division site involved in mitotic actomyosin contractile ring assembly,biological_process
91774,GO:1903477,Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly.,mitotic contractile ring actin filament bundle assembly,biological_process
91775,GO:1903479,Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.,mitotic actomyosin contractile ring assembly actin filament organization,biological_process
91776,GO:1903487,"Any process that modulates the frequency, rate or extent of lactation.",regulation of lactation,biological_process
91777,GO:1903488,"Any process that stops, prevents or reduces the frequency, rate or extent of lactation.",negative regulation of lactation,biological_process
91778,GO:1903489,"Any process that activates or increases the frequency, rate or extent of lactation.",positive regulation of lactation,biological_process
91779,GO:1903490,"Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.",positive regulation of mitotic cytokinesis,biological_process
91780,GO:1903491,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.",response to simvastatin,biological_process
91781,GO:1903492,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.",response to acetylsalicylate,biological_process
91782,GO:1903493,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.",response to clopidogrel,biological_process
91783,GO:1903494,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.",response to dehydroepiandrosterone,biological_process
91784,GO:1903495,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.",cellular response to dehydroepiandrosterone,biological_process
91785,GO:1903496,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.",response to 11-deoxycorticosterone,biological_process
91786,GO:1903497,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.",cellular response to 11-deoxycorticosterone,biological_process
91787,GO:1903498,The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.,bundle sheath cell differentiation,biological_process
91788,GO:1903499,"Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.",regulation of mitotic actomyosin contractile ring assembly,biological_process
91789,GO:1903500,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.",negative regulation of mitotic actomyosin contractile ring assembly,biological_process
91790,GO:1903501,"Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.",positive regulation of mitotic actomyosin contractile ring assembly,biological_process
91791,GO:1903502,A protein complex which is capable of translation repressor activity.,translation repressor complex,cellular_component
91792,GO:1903503,A protein complex which is capable of ATPase inhibitor activity.,ATPase inhibitor complex,cellular_component
91793,GO:1903504,"Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.",regulation of mitotic spindle checkpoint,biological_process
91794,GO:1903509,The chemical reactions and pathways involving liposaccharide.,liposaccharide metabolic process,biological_process
91795,GO:1903512,The chemical reactions and pathways involving phytanic acid.,phytanic acid metabolic process,biological_process
91796,GO:1903513,The directed movement of substances from endoplasmic reticulum to cytosol.,endoplasmic reticulum to cytosol transport,biological_process
91797,GO:1903514,The directed movement of calcium ion from endoplasmic reticulum to cytosol.,release of sequestered calcium ion into cytosol by endoplasmic reticulum,biological_process
91798,GO:1903515,The directed movement of calcium ion from cytosol to endoplasmic reticulum.,calcium ion transport from cytosol to endoplasmic reticulum,biological_process
91799,GO:1903516,"Any process that modulates the frequency, rate or extent of single strand break repair.",regulation of single strand break repair,biological_process
91800,GO:1903517,"Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.",negative regulation of single strand break repair,biological_process
91801,GO:1903518,"Any process that activates or increases the frequency, rate or extent of single strand break repair.",positive regulation of single strand break repair,biological_process
91802,GO:1903519,"Any process that modulates the frequency, rate or extent of mammary gland involution.",regulation of mammary gland involution,biological_process
91803,GO:1903520,"Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution.",negative regulation of mammary gland involution,biological_process
91804,GO:1903521,"Any process that activates or increases the frequency, rate or extent of mammary gland involution.",positive regulation of mammary gland involution,biological_process
91805,GO:1903522,"Any process that modulates the frequency, rate or extent of blood circulation.",regulation of blood circulation,biological_process
91806,GO:1903523,"Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.",negative regulation of blood circulation,biological_process
91807,GO:1903524,"Any process that activates or increases the frequency, rate or extent of blood circulation.",positive regulation of blood circulation,biological_process
91808,GO:1903525,"Any process that modulates the frequency, rate or extent of membrane tubulation.",regulation of membrane tubulation,biological_process
91809,GO:1903526,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.",negative regulation of membrane tubulation,biological_process
91810,GO:1903527,"Any process that activates or increases the frequency, rate or extent of membrane tubulation.",positive regulation of membrane tubulation,biological_process
91811,GO:1903528,"Any process that modulates the frequency, rate or extent of dCDP biosynthetic process.",regulation of dCDP biosynthetic process,biological_process
91812,GO:1903529,"Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.",negative regulation of dCDP biosynthetic process,biological_process
91813,GO:1903530,"Any process that modulates the frequency, rate or extent of secretion by cell.",regulation of secretion by cell,biological_process
91814,GO:1903531,"Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.",negative regulation of secretion by cell,biological_process
91815,GO:1903532,"Any process that activates or increases the frequency, rate or extent of secretion by cell.",positive regulation of secretion by cell,biological_process
91816,GO:1903533,"Any process that modulates the frequency, rate or extent of protein targeting.",regulation of protein targeting,biological_process
91817,GO:1903534,"Any process that modulates the frequency, rate or extent of lactose biosynthetic process.",regulation of lactose biosynthetic process,biological_process
91818,GO:1903535,"Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.",negative regulation of lactose biosynthetic process,biological_process
91819,GO:1903536,"Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.",positive regulation of lactose biosynthetic process,biological_process
91820,GO:1903537,Any meiotic cell cycle process that is involved in oocyte maturation.,meiotic cell cycle process involved in oocyte maturation,biological_process
91821,GO:1903538,"Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.",regulation of meiotic cell cycle process involved in oocyte maturation,biological_process
91822,GO:1903539,"A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.",protein localization to postsynaptic membrane,biological_process
91823,GO:1903540,The directed movement of a protein to a specific location in a postsynaptic membrane.,establishment of protein localization to postsynaptic membrane,biological_process
91824,GO:1903541,"Any process that modulates the frequency, rate or extent of exosomal secretion.",regulation of exosomal secretion,biological_process
91825,GO:1903542,"Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.",negative regulation of exosomal secretion,biological_process
91826,GO:1903543,"Any process that activates or increases the frequency, rate or extent of exosomal secretion.",positive regulation of exosomal secretion,biological_process
91827,GO:1903544,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.",response to butyrate,biological_process
91828,GO:1903545,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.",cellular response to butyrate,biological_process
91829,GO:1903546,"A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.",protein localization to photoreceptor outer segment,biological_process
91830,GO:1903551,"Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.",regulation of extracellular exosome assembly,biological_process
91831,GO:1903552,"Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.",negative regulation of extracellular exosome assembly,biological_process
91832,GO:1903553,"Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.",positive regulation of extracellular exosome assembly,biological_process
91833,GO:1903555,"Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.",regulation of tumor necrosis factor superfamily cytokine production,biological_process
91834,GO:1903556,"Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.",negative regulation of tumor necrosis factor superfamily cytokine production,biological_process
91835,GO:1903557,"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.",positive regulation of tumor necrosis factor superfamily cytokine production,biological_process
91836,GO:1903561,Any vesicle that is part of the extracellular region.,extracellular vesicle,cellular_component
91837,GO:1903564,"Any process that modulates the frequency, rate or extent of protein localization to cilium.",regulation of protein localization to cilium,biological_process
91838,GO:1903565,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.",negative regulation of protein localization to cilium,biological_process
91839,GO:1903566,"Any process that activates or increases the frequency, rate or extent of protein localization to cilium.",positive regulation of protein localization to cilium,biological_process
91840,GO:1903567,"Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.",regulation of protein localization to ciliary membrane,biological_process
91841,GO:1903568,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.",negative regulation of protein localization to ciliary membrane,biological_process
91842,GO:1903569,"Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.",positive regulation of protein localization to ciliary membrane,biological_process
91843,GO:1903573,"Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.",negative regulation of response to endoplasmic reticulum stress,biological_process
91844,GO:1903574,"Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation.",negative regulation of cellular response to amino acid starvation,biological_process
91845,GO:1903575,"The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.",cornified envelope assembly,biological_process
91846,GO:1903576,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.",response to L-arginine,biological_process
91847,GO:1903577,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.",cellular response to L-arginine,biological_process
91848,GO:1903578,"Any process that modulates the frequency, rate or extent of ATP metabolic process.",regulation of ATP metabolic process,biological_process
91849,GO:1903579,"Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.",negative regulation of ATP metabolic process,biological_process
91850,GO:1903580,"Any process that activates or increases the frequency, rate or extent of ATP metabolic process.",positive regulation of ATP metabolic process,biological_process
91851,GO:1903581,"Any process that modulates the frequency, rate or extent of basophil degranulation.",regulation of basophil degranulation,biological_process
91852,GO:1903582,"Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.",negative regulation of basophil degranulation,biological_process
91853,GO:1903583,"Any process that activates or increases the frequency, rate or extent of basophil degranulation.",positive regulation of basophil degranulation,biological_process
91854,GO:1903587,"Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.",regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis,biological_process
91855,GO:1903588,"Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.",negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis,biological_process
91856,GO:1903589,"Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.",positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis,biological_process
91857,GO:1903592,"Any process that activates or increases the frequency, rate or extent of lysozyme activity.",positive regulation of lysozyme activity,biological_process
91858,GO:1903593,"Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.",regulation of histamine secretion by mast cell,biological_process
91859,GO:1903594,"Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.",negative regulation of histamine secretion by mast cell,biological_process
91860,GO:1903595,"Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.",positive regulation of histamine secretion by mast cell,biological_process
91861,GO:1903596,"Any process that modulates the frequency, rate or extent of gap junction assembly.",regulation of gap junction assembly,biological_process
91862,GO:1903597,"Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.",negative regulation of gap junction assembly,biological_process
91863,GO:1903598,"Any process that activates or increases the frequency, rate or extent of gap junction assembly.",positive regulation of gap junction assembly,biological_process
91864,GO:1903599,"Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.",positive regulation of autophagy of mitochondrion,biological_process
91865,GO:1903600,A protein complex which is capable of glutaminase activity.,glutaminase complex,cellular_component
91866,GO:1903602,The chemical reactions and pathways resulting in the breakdown of thermospermine.,thermospermine catabolic process,biological_process
91867,GO:1903603,The chemical reactions and pathways resulting in the formation of thermospermine.,thermospermine biosynthetic process,biological_process
91868,GO:1903604,The chemical reactions and pathways involving a cytochrome.,cytochrome metabolic process,biological_process
91869,GO:1903605,The chemical reactions and pathways resulting in the formation of a cytochrome.,cytochrome biosynthetic process,biological_process
91870,GO:1903606,The chemical reactions and pathways involving cytochrome c.,cytochrome c metabolic process,biological_process
91871,GO:1903607,The chemical reactions and pathways resulting in the formation of cytochrome c.,cytochrome c biosynthetic process,biological_process
91872,GO:1903608,"A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.",protein localization to cytoplasmic stress granule,biological_process
91873,GO:1903609,"Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.",negative regulation of inward rectifier potassium channel activity,biological_process
91874,GO:1903611,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.",negative regulation of calcium-dependent ATPase activity,biological_process
91875,GO:1903612,"Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.",positive regulation of calcium-dependent ATPase activity,biological_process
91876,GO:1903617,"Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning.","positive regulation of mitotic cytokinesis, division site positioning",biological_process
91877,GO:1903618,"Any process that modulates the frequency, rate or extent of transdifferentiation.",regulation of transdifferentiation,biological_process
91878,GO:1903619,"Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation.",negative regulation of transdifferentiation,biological_process
91879,GO:1903620,"Any process that activates or increases the frequency, rate or extent of transdifferentiation.",positive regulation of transdifferentiation,biological_process
91880,GO:1903621,"A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.",protein localization to photoreceptor connecting cilium,biological_process
91881,GO:1903624,"Any process that modulates the frequency, rate or extent of DNA catabolic process.",regulation of DNA catabolic process,biological_process
91882,GO:1903625,"Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.",negative regulation of DNA catabolic process,biological_process
91883,GO:1903626,"Any process that activates or increases the frequency, rate or extent of DNA catabolic process.",positive regulation of DNA catabolic process,biological_process
91884,GO:1903639,"Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion.",regulation of gastrin-induced gastric acid secretion,biological_process
91885,GO:1903640,"Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.",negative regulation of gastrin-induced gastric acid secretion,biological_process
91886,GO:1903641,"Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion.",positive regulation of gastrin-induced gastric acid secretion,biological_process
91887,GO:1903647,"Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process.",negative regulation of chlorophyll catabolic process,biological_process
91888,GO:1903648,"Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.",positive regulation of chlorophyll catabolic process,biological_process
91889,GO:1903653,A process in which a symbiont alters or subverts cell motility in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host cell motility,biological_process
91890,GO:1903656,"Any process that modulates the frequency, rate or extent of type IV pilus biogenesis.",regulation of type IV pilus biogenesis,biological_process
91891,GO:1903657,"Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.",negative regulation of type IV pilus biogenesis,biological_process
91892,GO:1903658,"Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis.",positive regulation of type IV pilus biogenesis,biological_process
91893,GO:1903659,"Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.",regulation of complement-dependent cytotoxicity,biological_process
91894,GO:1903660,"Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.",negative regulation of complement-dependent cytotoxicity,biological_process
91895,GO:1903661,"Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.",positive regulation of complement-dependent cytotoxicity,biological_process
91896,GO:1903663,The chemical reactions and pathways resulting in the breakdown of L-altrarate.,L-altrarate catabolic process,biological_process
91897,GO:1903664,"Any process that modulates the frequency, rate or extent of asexual reproduction.",regulation of asexual reproduction,biological_process
91898,GO:1903665,"Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.",negative regulation of asexual reproduction,biological_process
91899,GO:1903666,"Any process that activates or increases the frequency, rate or extent of asexual reproduction.",positive regulation of asexual reproduction,biological_process
91900,GO:1903670,"Any process that modulates the frequency, rate or extent of sprouting angiogenesis.",regulation of sprouting angiogenesis,biological_process
91901,GO:1903671,"Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.",negative regulation of sprouting angiogenesis,biological_process
91902,GO:1903672,"Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.",positive regulation of sprouting angiogenesis,biological_process
91903,GO:1903673,Any cleavage furrow formation that is involved in mitotic cell cycle.,mitotic cleavage furrow formation,biological_process
91904,GO:1903674,"Any process that modulates the frequency, rate or extent of cap-dependent translational initiation.",regulation of cap-dependent translational initiation,biological_process
91905,GO:1903675,"Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation.",negative regulation of cap-dependent translational initiation,biological_process
91906,GO:1903676,"Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation.",positive regulation of cap-dependent translational initiation,biological_process
91907,GO:1903677,"Any process that modulates the frequency, rate or extent of cap-independent translational initiation.",regulation of cap-independent translational initiation,biological_process
91908,GO:1903678,"Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation.",negative regulation of cap-independent translational initiation,biological_process
91909,GO:1903679,"Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.",positive regulation of cap-independent translational initiation,biological_process
91910,GO:1903680,The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.,acinar cell of sebaceous gland differentiation,biological_process
91911,GO:1903684,"Any process that modulates the frequency, rate or extent of border follicle cell migration.",regulation of border follicle cell migration,biological_process
91912,GO:1903687,"Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.",negative regulation of border follicle cell migration,biological_process
91913,GO:1903688,"Any process that activates or increases the frequency, rate or extent of border follicle cell migration.",positive regulation of border follicle cell migration,biological_process
91914,GO:1903689,"Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.","regulation of wound healing, spreading of epidermal cells",biological_process
91915,GO:1903690,"Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.","negative regulation of wound healing, spreading of epidermal cells",biological_process
91916,GO:1903691,"Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.","positive regulation of wound healing, spreading of epidermal cells",biological_process
91917,GO:1903692,"The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol.",methionine import across plasma membrane,biological_process
91918,GO:1903696,"A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.",protein localization to horsetail-astral microtubule array,biological_process
91919,GO:1903697,"Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.",negative regulation of microvillus assembly,biological_process
91920,GO:1903698,"Any process that activates or increases the frequency, rate or extent of microvillus assembly.",positive regulation of microvillus assembly,biological_process
91921,GO:1903699,"The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.",tarsal gland development,biological_process
91922,GO:1903700,"The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.",caecum development,biological_process
91923,GO:1903701,"The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.",substantia propria of cornea development,biological_process
91924,GO:1903702,"The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.",esophagus development,biological_process
91925,GO:1903703,The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte.,enterocyte differentiation,biological_process
91926,GO:1903704,"Any process that stops, prevents or reduces the frequency, rate or extent of siRNA processing.",negative regulation of siRNA processing,biological_process
91927,GO:1903705,"Any process that activates or increases the frequency, rate or extent of siRNA processing.",positive regulation of siRNA processing,biological_process
91928,GO:1903706,"Any process that modulates the frequency, rate or extent of hemopoiesis.",regulation of hemopoiesis,biological_process
91929,GO:1903707,"Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.",negative regulation of hemopoiesis,biological_process
91930,GO:1903708,"Any process that activates or increases the frequency, rate or extent of hemopoiesis.",positive regulation of hemopoiesis,biological_process
91931,GO:1903709,"The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.",uterine gland development,biological_process
91932,GO:1903710,The process in which spermine is transported across a membrane.,spermine transmembrane transport,biological_process
91933,GO:1903711,The process in which spermidine is transported across a membrane.,spermidine transmembrane transport,biological_process
91934,GO:1903712,The directed movement of L-cysteine across a membrane.,L-cysteine transmembrane transport,biological_process
91935,GO:1903713,The directed movement of asparagine across a membrane.,asparagine transmembrane transport,biological_process
91936,GO:1903714,The directed movement of isoleucine across a membrane by means of some agent such as a transporter or a pore.,isoleucine transmembrane transport,biological_process
91937,GO:1903715,"Any process that modulates the frequency, rate or extent of aerobic respiration.",regulation of aerobic respiration,biological_process
91938,GO:1903716,The process in which guanine is transported across a membrane.,guanine transmembrane transport,biological_process
91939,GO:1903719,"Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation.",regulation of I-kappaB phosphorylation,biological_process
91940,GO:1903720,"Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.",negative regulation of I-kappaB phosphorylation,biological_process
91941,GO:1903721,"Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.",positive regulation of I-kappaB phosphorylation,biological_process
91942,GO:1903722,"Any process that modulates the frequency, rate or extent of centriole elongation.",regulation of centriole elongation,biological_process
91943,GO:1903723,"Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.",negative regulation of centriole elongation,biological_process
91944,GO:1903724,"Any process that activates or increases the frequency, rate or extent of centriole elongation.",positive regulation of centriole elongation,biological_process
91945,GO:1903725,"Any process that modulates the frequency, rate or extent of phospholipid metabolic process.",regulation of phospholipid metabolic process,biological_process
91946,GO:1903726,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.",negative regulation of phospholipid metabolic process,biological_process
91947,GO:1903727,"Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.",positive regulation of phospholipid metabolic process,biological_process
91948,GO:1903728,The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.,luteal cell differentiation,biological_process
91949,GO:1903729,"Any process that modulates the frequency, rate or extent of plasma membrane organization.",regulation of plasma membrane organization,biological_process
91950,GO:1903742,"Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.",regulation of anterograde synaptic vesicle transport,biological_process
91951,GO:1903743,"Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport.",negative regulation of anterograde synaptic vesicle transport,biological_process
91952,GO:1903744,"Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.",positive regulation of anterograde synaptic vesicle transport,biological_process
91953,GO:1903745,"Any process that stops, prevents or reduces the frequency, rate or extent of nematode pharyngeal pumping.",negative regulation of nematode pharyngeal pumping,biological_process
91954,GO:1903746,"Any process that activates or increases the frequency, rate or extent of nematode pharyngeal pumping.",positive regulation of nematode pharyngeal pumping,biological_process
91955,GO:1903747,"Any process that modulates the frequency, rate or extent of protein localization to mitochondrion.",regulation of protein localization to mitochondrion,biological_process
91956,GO:1903748,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitochondrion.",negative regulation of protein localization to mitochondrion,biological_process
91957,GO:1903749,"Any process that activates or increases the frequency, rate or extent of protein localization to mitochondrion.",positive regulation of protein localization to mitochondrion,biological_process
91958,GO:1903750,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.",regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide,biological_process
91959,GO:1903751,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.",negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide,biological_process
91960,GO:1903752,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.",positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide,biological_process
91961,GO:1903753,"Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.",negative regulation of p38MAPK cascade,biological_process
91962,GO:1903754,The plus-end of a cortical microtubule.,cortical microtubule plus-end,cellular_component
91963,GO:1903763,Any gap junction channel activity that is involved in cell communication by electrical coupling.,gap junction channel activity involved in cell communication by electrical coupling,molecular_function
91964,GO:1903764,"Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.",regulation of potassium ion export across plasma membrane,biological_process
91965,GO:1903765,"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.",negative regulation of potassium ion export across plasma membrane,biological_process
91966,GO:1903766,"Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.",positive regulation of potassium ion export across plasma membrane,biological_process
91967,GO:1903767,A protein complex which is capable of sweet taste receptor activity.,sweet taste receptor complex,cellular_component
91968,GO:1903768,A protein complex which is capable of taste receptor activity.,taste receptor complex,cellular_component
91969,GO:1903769,"Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.",negative regulation of cell proliferation in bone marrow,biological_process
91970,GO:1903770,"Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity.",negative regulation of beta-galactosidase activity,biological_process
91971,GO:1903771,"Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.",positive regulation of beta-galactosidase activity,biological_process
91972,GO:1903772,"Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.",regulation of viral budding via host ESCRT complex,biological_process
91973,GO:1903773,"Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex.",negative regulation of viral budding via host ESCRT complex,biological_process
91974,GO:1903774,"Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.",positive regulation of viral budding via host ESCRT complex,biological_process
91975,GO:1903775,"Any process that modulates the frequency, rate or extent of DNA double-strand break processing.",regulation of DNA double-strand break processing,biological_process
91976,GO:1903776,"Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.","regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends",biological_process
91977,GO:1903777,Binding to melibiose.,melibiose binding,molecular_function
91978,GO:1903778,"A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.",protein localization to vacuolar membrane,biological_process
91979,GO:1903779,"Any process that modulates the frequency, rate or extent of cardiac conduction.",regulation of cardiac conduction,biological_process
91980,GO:1903780,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.",negative regulation of cardiac conduction,biological_process
91981,GO:1903781,"Any process that activates or increases the frequency, rate or extent of cardiac conduction.",positive regulation of cardiac conduction,biological_process
91982,GO:1903782,"Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.",regulation of sodium ion import across plasma membrane,biological_process
91983,GO:1903783,"Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.",negative regulation of sodium ion import across plasma membrane,biological_process
91984,GO:1903784,"Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.",positive regulation of sodium ion import across plasma membrane,biological_process
91985,GO:1903785,The directed movement of L-valine across a membrane.,L-valine transmembrane transport,biological_process
91986,GO:1903786,"Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.",regulation of glutathione biosynthetic process,biological_process
91987,GO:1903787,"Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.",negative regulation of glutathione biosynthetic process,biological_process
91988,GO:1903788,"Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.",positive regulation of glutathione biosynthetic process,biological_process
91989,GO:1903789,"Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.",regulation of amino acid transmembrane transport,biological_process
91990,GO:1903790,The process in which a guanyl nucleotide is transported across a membrane.,guanine nucleotide transmembrane transport,biological_process
91991,GO:1903791,The process in which uracil is transported across a membrane.,uracil transmembrane transport,biological_process
91992,GO:1903792,"Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.",negative regulation of monoatomic anion transport,biological_process
91993,GO:1903793,"Any process that activates or increases the frequency, rate or extent of anion transport.",positive regulation of monoatomic anion transport,biological_process
91994,GO:1903794,Binding to cortisol.,cortisol binding,molecular_function
91995,GO:1903798,"Any process that modulates the frequency, rate or extent of microRNA processing.",regulation of miRNA processing,biological_process
91996,GO:1903799,"Any process that stops, prevents or reduces the frequency, rate or extent of microRNA processing.",negative regulation of miRNA processing,biological_process
91997,GO:1903800,"Any process that activates or increases the frequency, rate or extent of microRNA processing.",positive regulation of miRNA processing,biological_process
91998,GO:1903801,"The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol.",L-leucine import across plasma membrane,biological_process
91999,GO:1903803,"The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol.",L-glutamine import across plasma membrane,biological_process
92000,GO:1903804,"The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol.",glycine import across plasma membrane,biological_process
92001,GO:1903805,"The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol.",L-valine import across plasma membrane,biological_process
92002,GO:1903806,"The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol.",L-isoleucine import across plasma membrane,biological_process
92003,GO:1903807,"The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol.",L-threonine import across plasma membrane,biological_process
92004,GO:1903808,"The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol.",L-tyrosine import across plasma membrane,biological_process
92005,GO:1903810,"The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol.",L-histidine import across plasma membrane,biological_process
92006,GO:1903811,"The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol.",L-asparagine import across plasma membrane,biological_process
92007,GO:1903812,The directed movement of L-serine into a cell.,L-serine import across plasma membrane,biological_process
92008,GO:1903814,"Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.",regulation of collecting lymphatic vessel constriction,biological_process
92009,GO:1903815,"Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.",negative regulation of collecting lymphatic vessel constriction,biological_process
92010,GO:1903816,"Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction.",positive regulation of collecting lymphatic vessel constriction,biological_process
92011,GO:1903817,"Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.",negative regulation of voltage-gated potassium channel activity,biological_process
92012,GO:1903818,"Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.",positive regulation of voltage-gated potassium channel activity,biological_process
92013,GO:1903823,Single strand break repair that takes place in a telomere.,telomere single strand break repair,biological_process
92014,GO:1903824,"Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.",negative regulation of telomere single strand break repair,biological_process
92015,GO:1903826,The directed movement of L-arginine across a membrane.,L-arginine transmembrane transport,biological_process
92016,GO:1903828,"Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization.",negative regulation of protein localization,biological_process
92017,GO:1903829,"Any process that activates or increases the frequency, rate or extent of a protein localization.",positive regulation of protein localization,biological_process
92018,GO:1903830,The directed movement of magnesium ion across a membrane.,magnesium ion transmembrane transport,biological_process
92019,GO:1903831,Any signal transduction that is involved in cellular response to ammonium ion.,signal transduction involved in cellular response to ammonium ion,biological_process
92020,GO:1903832,"Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation.",regulation of cellular response to amino acid starvation,biological_process
92021,GO:1903833,"Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.",positive regulation of cellular response to amino acid starvation,biological_process
92022,GO:1903840,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.",response to arsenite(3-),biological_process
92023,GO:1903841,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.",cellular response to arsenite(3-),biological_process
92024,GO:1903842,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.",response to arsenite ion,biological_process
92025,GO:1903843,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.",cellular response to arsenite ion,biological_process
92026,GO:1903844,"Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.",regulation of cellular response to transforming growth factor beta stimulus,biological_process
92027,GO:1903845,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.",negative regulation of cellular response to transforming growth factor beta stimulus,biological_process
92028,GO:1903846,"Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.",positive regulation of cellular response to transforming growth factor beta stimulus,biological_process
92029,GO:1903847,"Any process that modulates the frequency, rate or extent of aorta morphogenesis.",regulation of aorta morphogenesis,biological_process
92030,GO:1903848,"Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.",negative regulation of aorta morphogenesis,biological_process
92031,GO:1903849,"Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.",positive regulation of aorta morphogenesis,biological_process
92032,GO:1903850,"Any process that modulates the frequency, rate or extent of cristae formation.",regulation of cristae formation,biological_process
92033,GO:1903851,"Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.",negative regulation of cristae formation,biological_process
92034,GO:1903852,"Any process that activates or increases the frequency, rate or extent of cristae formation.",positive regulation of cristae formation,biological_process
92035,GO:1903853,"Any process that modulates the frequency, rate or extent of stress response to copper ion.",regulation of stress response to copper ion,biological_process
92036,GO:1903854,"Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.",negative regulation of stress response to copper ion,biological_process
92037,GO:1903855,"Any process that activates or increases the frequency, rate or extent of stress response to copper ion.",positive regulation of stress response to copper ion,biological_process
92038,GO:1903858,"A process in which a protein is transported to, or maintained in, a location within an old growing cell tip.",protein localization to old growing cell tip,biological_process
92039,GO:1903859,"Any process that modulates the frequency, rate or extent of dendrite extension.",regulation of dendrite extension,biological_process
92040,GO:1903860,"Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.",negative regulation of dendrite extension,biological_process
92041,GO:1903861,"Any process that activates or increases the frequency, rate or extent of dendrite extension.",positive regulation of dendrite extension,biological_process
92042,GO:1903862,"Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.",positive regulation of oxidative phosphorylation,biological_process
92043,GO:1903863,"The aggregation, arrangement and bonding together of a set of components to form a P granule.",P granule assembly,biological_process
92044,GO:1903864,The disaggregation of a P granule into its constituent components.,P granule disassembly,biological_process
92045,GO:1903865,A protein complex which is capable of sigma factor antagonist activity.,sigma factor antagonist complex,cellular_component
92046,GO:1903866,"The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure.",palisade mesophyll development,biological_process
92047,GO:1903867,"The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.",extraembryonic membrane development,biological_process
92048,GO:1903871,"The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex.",DNA recombinase mediator complex assembly,biological_process
92049,GO:1903872,"Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly.",regulation of DNA recombinase mediator complex assembly,biological_process
92050,GO:1903873,"Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.",negative regulation of DNA recombinase mediator complex assembly,biological_process
92051,GO:1903875,Binding to corticosterone.,corticosterone binding,molecular_function
92052,GO:1903876,Binding to 11-deoxycortisol.,11-deoxycortisol binding,molecular_function
92053,GO:1903877,Binding to 21-deoxycortisol.,21-deoxycortisol binding,molecular_function
92054,GO:1903878,Binding to 11-deoxycorticosterone.,11-deoxycorticosterone binding,molecular_function
92055,GO:1903879,Binding to 11beta-hydroxyprogesterone.,11beta-hydroxyprogesterone binding,molecular_function
92056,GO:1903880,Binding to 17alpha-hydroxyprogesterone.,17alpha-hydroxyprogesterone binding,molecular_function
92057,GO:1903881,"Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.",regulation of interleukin-17-mediated signaling pathway,biological_process
92058,GO:1903882,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.",negative regulation of interleukin-17-mediated signaling pathway,biological_process
92059,GO:1903883,"Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.",positive regulation of interleukin-17-mediated signaling pathway,biological_process
92060,GO:1903884,"Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.",regulation of chemokine (C-C motif) ligand 20 production,biological_process
92061,GO:1903885,"Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.",negative regulation of chemokine (C-C motif) ligand 20 production,biological_process
92062,GO:1903886,"Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.",positive regulation of chemokine (C-C motif) ligand 20 production,biological_process
92063,GO:1903888,"Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation.",regulation of plant epidermal cell differentiation,biological_process
92064,GO:1903889,"Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation.",negative regulation of plant epidermal cell differentiation,biological_process
92065,GO:1903890,"Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation.",positive regulation of plant epidermal cell differentiation,biological_process
92066,GO:1903891,"Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.",regulation of ATF6-mediated unfolded protein response,biological_process
92067,GO:1903892,"Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.",negative regulation of ATF6-mediated unfolded protein response,biological_process
92068,GO:1903893,"Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.",positive regulation of ATF6-mediated unfolded protein response,biological_process
92069,GO:1903894,"Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.",regulation of IRE1-mediated unfolded protein response,biological_process
92070,GO:1903895,"Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.",negative regulation of IRE1-mediated unfolded protein response,biological_process
92071,GO:1903896,"Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.",positive regulation of IRE1-mediated unfolded protein response,biological_process
92072,GO:1903897,"Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.",regulation of PERK-mediated unfolded protein response,biological_process
92073,GO:1903898,"Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.",negative regulation of PERK-mediated unfolded protein response,biological_process
92074,GO:1903899,"Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.",positive regulation of PERK-mediated unfolded protein response,biological_process
92075,GO:1903900,"Any process that modulates the frequency, rate or extent of viral life cycle.",regulation of viral life cycle,biological_process
92076,GO:1903901,"Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.",negative regulation of viral life cycle,biological_process
92077,GO:1903902,"Any process that activates or increases the frequency, rate or extent of viral life cycle.",positive regulation of viral life cycle,biological_process
92078,GO:1903903,"Any process that modulates the frequency, rate or extent of establishment of T cell polarity.",regulation of establishment of T cell polarity,biological_process
92079,GO:1903904,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.",negative regulation of establishment of T cell polarity,biological_process
92080,GO:1903905,"Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.",positive regulation of establishment of T cell polarity,biological_process
92081,GO:1903906,"Any process that modulates the frequency, rate or extent of plasma membrane raft polarization.",regulation of plasma membrane raft polarization,biological_process
92082,GO:1903907,"Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.",negative regulation of plasma membrane raft polarization,biological_process
92083,GO:1903908,"Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.",positive regulation of plasma membrane raft polarization,biological_process
92084,GO:1903909,"Any process that modulates the frequency, rate or extent of receptor clustering.",regulation of receptor clustering,biological_process
92085,GO:1903910,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.",negative regulation of receptor clustering,biological_process
92086,GO:1903911,"Any process that activates or increases the frequency, rate or extent of receptor clustering.",positive regulation of receptor clustering,biological_process
92087,GO:1903912,"Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.",negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation,biological_process
92088,GO:1903913,"Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.",regulation of fusion of virus membrane with host plasma membrane,biological_process
92089,GO:1903914,"Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.",negative regulation of fusion of virus membrane with host plasma membrane,biological_process
92090,GO:1903915,"Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane.",positive regulation of fusion of virus membrane with host plasma membrane,biological_process
92091,GO:1903918,"Any process that modulates the frequency, rate or extent of actin filament severing.",regulation of actin filament severing,biological_process
92092,GO:1903919,"Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.",negative regulation of actin filament severing,biological_process
92093,GO:1903920,"Any process that activates or increases the frequency, rate or extent of actin filament severing.",positive regulation of actin filament severing,biological_process
92094,GO:1903921,"Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle.",regulation of protein processing in phagocytic vesicle,biological_process
92095,GO:1903922,"Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle.",negative regulation of protein processing in phagocytic vesicle,biological_process
92096,GO:1903923,"Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.",positive regulation of protein processing in phagocytic vesicle,biological_process
92097,GO:1903924,Binding to estradiol.,estradiol binding,molecular_function
92098,GO:1903925,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.",response to bisphenol A,biological_process
92099,GO:1903926,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.",cellular response to bisphenol A,biological_process
92100,GO:1903927,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.",response to cyanide,biological_process
92101,GO:1903928,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.",cellular response to cyanide,biological_process
92102,GO:1903929,"The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.",primary palate development,biological_process
92103,GO:1903930,"Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage.",regulation of pyrimidine-containing compound salvage,biological_process
92104,GO:1903931,"Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.",positive regulation of pyrimidine-containing compound salvage,biological_process
92105,GO:1903935,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.",response to sodium arsenite,biological_process
92106,GO:1903936,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.",cellular response to sodium arsenite,biological_process
92107,GO:1903937,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.",response to acrylamide,biological_process
92108,GO:1903938,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.",cellular response to acrylamide,biological_process
92109,GO:1903939,"Any process that modulates the frequency, rate or extent of TORC2 signaling.",regulation of TORC2 signaling,biological_process
92110,GO:1903940,"Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling.",negative regulation of TORC2 signaling,biological_process
92111,GO:1903941,"Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.",negative regulation of respiratory gaseous exchange,biological_process
92112,GO:1903942,"Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.",positive regulation of respiratory gaseous exchange,biological_process
92113,GO:1903943,"Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.",regulation of hepatocyte apoptotic process,biological_process
92114,GO:1903944,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.",negative regulation of hepatocyte apoptotic process,biological_process
92115,GO:1903945,"Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.",positive regulation of hepatocyte apoptotic process,biological_process
92116,GO:1903946,"Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.",negative regulation of ventricular cardiac muscle cell action potential,biological_process
92117,GO:1903947,"Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential.",positive regulation of ventricular cardiac muscle cell action potential,biological_process
92118,GO:1903948,"Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.",negative regulation of atrial cardiac muscle cell action potential,biological_process
92119,GO:1903949,"Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.",positive regulation of atrial cardiac muscle cell action potential,biological_process
92120,GO:1903950,"Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.",negative regulation of AV node cell action potential,biological_process
92121,GO:1903951,"Any process that activates or increases the frequency, rate or extent of AV node cell action potential.",positive regulation of AV node cell action potential,biological_process
92122,GO:1903958,A protein complex which is capable of nitric-oxide synthase activity.,nitric-oxide synthase complex,cellular_component
92123,GO:1903959,"Any process that modulates the frequency, rate or extent of anion transmembrane transport.",regulation of monoatomic anion transmembrane transport,biological_process
92124,GO:1903960,"Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.",negative regulation of anion transmembrane transport,biological_process
92125,GO:1903961,"Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.",positive regulation of anion transmembrane transport,biological_process
92126,GO:1903962,Enables the transfer of arachidonate from one side of a membrane to the other.,arachidonate transmembrane transporter activity,molecular_function
92127,GO:1903963,"The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",arachidonate transport,biological_process
92128,GO:1903965,The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.,monounsaturated fatty acid catabolic process,biological_process
92129,GO:1903966,The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.,monounsaturated fatty acid biosynthetic process,biological_process
92130,GO:1903967,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.",response to micafungin,biological_process
92131,GO:1903968,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.",cellular response to micafungin,biological_process
92132,GO:1903969,"Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor.",regulation of response to macrophage colony-stimulating factor,biological_process
92133,GO:1903970,"Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor.",negative regulation of response to macrophage colony-stimulating factor,biological_process
92134,GO:1903971,"Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.",positive regulation of response to macrophage colony-stimulating factor,biological_process
92135,GO:1903972,"Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.",regulation of cellular response to macrophage colony-stimulating factor stimulus,biological_process
92136,GO:1903973,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.",negative regulation of cellular response to macrophage colony-stimulating factor stimulus,biological_process
92137,GO:1903974,"Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.",positive regulation of cellular response to macrophage colony-stimulating factor stimulus,biological_process
92138,GO:1903975,"Any process that modulates the frequency, rate or extent of glial cell migration.",regulation of glial cell migration,biological_process
92139,GO:1903976,"Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.",negative regulation of glial cell migration,biological_process
92140,GO:1903977,"Any process that activates or increases the frequency, rate or extent of glial cell migration.",positive regulation of glial cell migration,biological_process
92141,GO:1903978,"Any process that modulates the frequency, rate or extent of microglial cell activation.",regulation of microglial cell activation,biological_process
92142,GO:1903979,"Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.",negative regulation of microglial cell activation,biological_process
92143,GO:1903980,"Any process that activates or increases the frequency, rate or extent of microglial cell activation.",positive regulation of microglial cell activation,biological_process
92144,GO:1903981,Binding to enterobactin.,enterobactin binding,molecular_function
92145,GO:1903982,A process that decreases the length of a microvillus.,negative regulation of microvillus length,biological_process
92146,GO:1903983,A process that increases the length of a microvillus.,positive regulation of microvillus length,biological_process
92147,GO:1903984,"Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.",positive regulation of TRAIL-activated apoptotic signaling pathway,biological_process
92148,GO:1903985,"Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.",regulation of intestinal D-glucose absorption,biological_process
92149,GO:1903988,"The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.",iron ion export across plasma membrane,biological_process
92150,GO:1903998,"Any process that modulates the frequency, rate or extent of eating behavior.",regulation of eating behavior,biological_process
92151,GO:1903999,"Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.",negative regulation of eating behavior,biological_process
92152,GO:1904000,"Any process that activates or increases the frequency, rate or extent of eating behavior.",positive regulation of eating behavior,biological_process
92153,GO:1904002,"Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.",regulation of sebum secreting cell proliferation,biological_process
92154,GO:1904003,"Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.",negative regulation of sebum secreting cell proliferation,biological_process
92155,GO:1904004,"Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.",positive regulation of sebum secreting cell proliferation,biological_process
92156,GO:1904010,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.",response to Aroclor 1254,biological_process
92157,GO:1904011,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.",cellular response to Aroclor 1254,biological_process
92158,GO:1904014,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.",response to serotonin,biological_process
92159,GO:1904015,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.",cellular response to serotonin,biological_process
92160,GO:1904016,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.",response to Thyroglobulin triiodothyronine,biological_process
92161,GO:1904017,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.",cellular response to Thyroglobulin triiodothyronine,biological_process
92162,GO:1904018,"Any process that activates or increases the frequency, rate or extent of vasculature development.",positive regulation of vasculature development,biological_process
92163,GO:1904019,Any apoptotic process in an epithelial cell.,epithelial cell apoptotic process,biological_process
92164,GO:1904020,"Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization.",regulation of G protein-coupled receptor internalization,biological_process
92165,GO:1904021,"Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.",negative regulation of G protein-coupled receptor internalization,biological_process
92166,GO:1904022,"Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization.",positive regulation of G protein-coupled receptor internalization,biological_process
92167,GO:1904023,"Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.",regulation of glucose catabolic process to lactate via pyruvate,biological_process
92168,GO:1904024,"Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.",negative regulation of glucose catabolic process to lactate via pyruvate,biological_process
92169,GO:1904025,"Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.",positive regulation of glucose catabolic process to lactate via pyruvate,biological_process
92170,GO:1904026,"Any process that modulates the frequency, rate or extent of collagen fibril organization.",regulation of collagen fibril organization,biological_process
92171,GO:1904027,"Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.",negative regulation of collagen fibril organization,biological_process
92172,GO:1904028,"Any process that activates or increases the frequency, rate or extent of collagen fibril organization.",positive regulation of collagen fibril organization,biological_process
92173,GO:1904030,"Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.",negative regulation of cyclin-dependent protein kinase activity,biological_process
92174,GO:1904031,"Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.",positive regulation of cyclin-dependent protein kinase activity,biological_process
92175,GO:1904032,"Any process that modulates the frequency, rate or extent of t-SNARE clustering.",regulation of t-SNARE clustering,biological_process
92176,GO:1904033,"Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.",negative regulation of t-SNARE clustering,biological_process
92177,GO:1904034,"Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.",positive regulation of t-SNARE clustering,biological_process
92178,GO:1904035,"Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.",regulation of epithelial cell apoptotic process,biological_process
92179,GO:1904036,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.",negative regulation of epithelial cell apoptotic process,biological_process
92180,GO:1904037,"Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.",positive regulation of epithelial cell apoptotic process,biological_process
92181,GO:1904038,"Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.",regulation of iron export across plasma membrane,biological_process
92182,GO:1904039,"Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.",negative regulation of iron export across plasma membrane,biological_process
92183,GO:1904040,"Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.",positive regulation of iron export across plasma membrane,biological_process
92184,GO:1904044,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.",response to aldosterone,biological_process
92185,GO:1904045,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.",cellular response to aldosterone,biological_process
92186,GO:1904046,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.",negative regulation of vascular endothelial growth factor production,biological_process
92187,GO:1904047,Binding to S-adenosyl-L-methionine.,S-adenosyl-L-methionine binding,molecular_function
92188,GO:1904048,"Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.",regulation of spontaneous neurotransmitter secretion,biological_process
92189,GO:1904049,"Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.",negative regulation of spontaneous neurotransmitter secretion,biological_process
92190,GO:1904050,"Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.",positive regulation of spontaneous neurotransmitter secretion,biological_process
92191,GO:1904054,"Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.",regulation of cholangiocyte proliferation,biological_process
92192,GO:1904055,"Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.",negative regulation of cholangiocyte proliferation,biological_process
92193,GO:1904056,"Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.",positive regulation of cholangiocyte proliferation,biological_process
92194,GO:1904057,"Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.",negative regulation of sensory perception of pain,biological_process
92195,GO:1904058,"Any process that activates or increases the frequency, rate or extent of sensory perception of pain.",positive regulation of sensory perception of pain,biological_process
92196,GO:1904059,"Any process that modulates the frequency, rate or extent of locomotor rhythm.",regulation of locomotor rhythm,biological_process
92197,GO:1904060,"Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.",negative regulation of locomotor rhythm,biological_process
92198,GO:1904061,"Any process that activates or increases the frequency, rate or extent of locomotor rhythm.",positive regulation of locomotor rhythm,biological_process
92199,GO:1904062,"Any process that modulates the frequency, rate or extent of cation transmembrane transport.",regulation of monoatomic cation transmembrane transport,biological_process
92200,GO:1904063,"Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.",negative regulation of cation transmembrane transport,biological_process
92201,GO:1904064,"Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.",positive regulation of cation transmembrane transport,biological_process
92202,GO:1904067,Binding to ascr#2.,ascr#2 binding,molecular_function
92203,GO:1904068,Any G protein-coupled receptor signaling pathway that is involved in social behavior.,G protein-coupled receptor signaling pathway involved in social behavior,biological_process
92204,GO:1904070,The chemical reactions and pathways resulting in the formation of ascaroside.,ascaroside biosynthetic process,biological_process
92205,GO:1904071,"The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.",presynaptic active zone assembly,biological_process
92206,GO:1904072,The disaggregation of a presynaptic active zone into its constituent components.,presynaptic active zone disassembly,biological_process
92207,GO:1904073,"Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.",regulation of trophectodermal cell proliferation,biological_process
92208,GO:1904074,"Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.",negative regulation of trophectodermal cell proliferation,biological_process
92209,GO:1904075,"Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.",positive regulation of trophectodermal cell proliferation,biological_process
92210,GO:1904076,"Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.",regulation of estrogen biosynthetic process,biological_process
92211,GO:1904077,"Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.",negative regulation of estrogen biosynthetic process,biological_process
92212,GO:1904078,"Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.",positive regulation of estrogen biosynthetic process,biological_process
92213,GO:1904082,The process in which pyrimidine is transported across a membrane.,pyrimidine nucleobase transmembrane transport,biological_process
92214,GO:1904086,"Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.",regulation of epiboly involved in gastrulation with mouth forming second,biological_process
92215,GO:1904087,"Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.",negative regulation of epiboly involved in gastrulation with mouth forming second,biological_process
92216,GO:1904088,"Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.",positive regulation of epiboly involved in gastrulation with mouth forming second,biological_process
92217,GO:1904090,A protein complex which is capable of peptidase inhibitor activity.,peptidase inhibitor complex,cellular_component
92218,GO:1904091,"Catalysis of a multistep reaction that produce non-ribosomal peptides. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core cha...",non-ribosomal peptide synthetase activity,molecular_function
92219,GO:1904092,"Any process that modulates the frequency, rate or extent of autophagic cell death.",regulation of autophagic cell death,biological_process
92220,GO:1904093,"Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.",negative regulation of autophagic cell death,biological_process
92221,GO:1904094,"Any process that activates or increases the frequency, rate or extent of autophagic cell death.",positive regulation of autophagic cell death,biological_process
92222,GO:1904095,"Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.",negative regulation of endosperm development,biological_process
92223,GO:1904096,A protein complex which is capable of protein tyrosine phosphatase activity.,protein tyrosine phosphatase complex,cellular_component
92224,GO:1904097,A protein complex which is capable of acid phosphatase activity.,acid phosphatase complex,cellular_component
92225,GO:1904098,"Any process that modulates the frequency, rate or extent of protein O-linked glycosylation.",regulation of protein O-linked glycosylation,biological_process
92226,GO:1904099,"Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation.",negative regulation of protein O-linked glycosylation,biological_process
92227,GO:1904100,"Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.",positive regulation of protein O-linked glycosylation,biological_process
92228,GO:1904101,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.",response to acadesine,biological_process
92229,GO:1904102,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.",cellular response to acadesine,biological_process
92230,GO:1904103,"Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.",regulation of convergent extension involved in gastrulation,biological_process
92231,GO:1904105,"Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation.",positive regulation of convergent extension involved in gastrulation,biological_process
92232,GO:1904106,"A process in which a protein is transported to, or maintained in, a location within a microvillus.",protein localization to microvillus,biological_process
92233,GO:1904107,"A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.",protein localization to microvillus membrane,biological_process
92234,GO:1904108,"A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.",protein localization to ciliary inversin compartment,biological_process
92235,GO:1904109,"Any process that activates or increases the frequency, rate or extent of cholesterol import.",positive regulation of cholesterol import,biological_process
92236,GO:1904113,"Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding.",negative regulation of muscle filament sliding,biological_process
92237,GO:1904114,"Any process that activates or increases the frequency, rate or extent of muscle filament sliding.",positive regulation of muscle filament sliding,biological_process
92238,GO:1904115,Any cytoplasm that is part of a axon.,axon cytoplasm,cellular_component
92239,GO:1904116,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.",response to vasopressin,biological_process
92240,GO:1904117,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.",cellular response to vasopressin,biological_process
92241,GO:1904118,"Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.",regulation of otic vesicle morphogenesis,biological_process
92242,GO:1904119,"Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.",negative regulation of otic vesicle morphogenesis,biological_process
92243,GO:1904120,"Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.",positive regulation of otic vesicle morphogenesis,biological_process
92244,GO:1904121,"Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.",phosphatidylethanolamine transfer activity,molecular_function
92245,GO:1904124,The orderly movement of a microglial cell from one site to another.,microglial cell migration,biological_process
92246,GO:1904126,Any convergent extension that is involved in notochord morphogenesis.,convergent extension involved in notochord morphogenesis,biological_process
92247,GO:1904139,"Any process that modulates the frequency, rate or extent of microglial cell migration.",regulation of microglial cell migration,biological_process
92248,GO:1904140,"Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.",negative regulation of microglial cell migration,biological_process
92249,GO:1904141,"Any process that activates or increases the frequency, rate or extent of microglial cell migration.",positive regulation of microglial cell migration,biological_process
92250,GO:1904142,"Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.",negative regulation of carotenoid biosynthetic process,biological_process
92251,GO:1904143,"Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.",positive regulation of carotenoid biosynthetic process,biological_process
92252,GO:1904144,A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.,phosphatidylinositol phosphate phosphatase complex,cellular_component
92253,GO:1904145,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.",negative regulation of meiotic cell cycle process involved in oocyte maturation,biological_process
92254,GO:1904146,"Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.",positive regulation of meiotic cell cycle process involved in oocyte maturation,biological_process
92255,GO:1904147,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.",response to nonylphenol,biological_process
92256,GO:1904148,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.",cellular response to nonylphenol,biological_process
92257,GO:1904149,"Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity.",regulation of microglial cell mediated cytotoxicity,biological_process
92258,GO:1904150,"Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.",negative regulation of microglial cell mediated cytotoxicity,biological_process
92259,GO:1904151,"Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.",positive regulation of microglial cell mediated cytotoxicity,biological_process
92260,GO:1904152,"Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.","regulation of retrograde protein transport, ER to cytosol",biological_process
92261,GO:1904153,"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.","negative regulation of retrograde protein transport, ER to cytosol",biological_process
92262,GO:1904154,"Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.","positive regulation of retrograde protein transport, ER to cytosol",biological_process
92263,GO:1904155,"The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.",DN2 thymocyte differentiation,biological_process
92264,GO:1904156,"The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.",DN3 thymocyte differentiation,biological_process
92265,GO:1904157,"The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-.",DN4 thymocyte differentiation,biological_process
92266,GO:1904158,"The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus.",axonemal central apparatus assembly,biological_process
92267,GO:1904159,The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte.,megasporocyte differentiation,biological_process
92268,GO:1904160,"A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.",protein localization to chloroplast starch grain,biological_process
92269,GO:1904161,Any DNA synthesis that is involved in UV-damage excision repair.,DNA synthesis involved in UV-damage excision repair,biological_process
92270,GO:1904170,"Any process that modulates the frequency, rate or extent of bleb assembly.",regulation of bleb assembly,biological_process
92271,GO:1904171,"Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.",negative regulation of bleb assembly,biological_process
92272,GO:1904172,"Any process that activates or increases the frequency, rate or extent of bleb assembly.",positive regulation of bleb assembly,biological_process
92273,GO:1904176,A protein complex which is capable of carbon phosphorus lyase activity.,carbon phosphorus lyase complex,cellular_component
92274,GO:1904177,"Any process that modulates the frequency, rate or extent of adipose tissue development.",regulation of adipose tissue development,biological_process
92275,GO:1904178,"Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.",negative regulation of adipose tissue development,biological_process
92276,GO:1904179,"Any process that activates or increases the frequency, rate or extent of adipose tissue development.",positive regulation of adipose tissue development,biological_process
92277,GO:1904180,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization.",negative regulation of membrane depolarization,biological_process
92278,GO:1904181,"Any process that activates or increases the frequency, rate or extent of membrane depolarization.",positive regulation of membrane depolarization,biological_process
92279,GO:1904185,"The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.",equatorial microtubule organizing center assembly,biological_process
92280,GO:1904186,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.",post-anaphase microtubule array organization,biological_process
92281,GO:1904187,"Any process that modulates the frequency, rate or extent of transformation of host cell by virus.",regulation of transformation of host cell by virus,biological_process
92282,GO:1904188,"Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.",negative regulation of transformation of host cell by virus,biological_process
92283,GO:1904189,"Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.",positive regulation of transformation of host cell by virus,biological_process
92284,GO:1904192,"Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.",regulation of cholangiocyte apoptotic process,biological_process
92285,GO:1904193,"Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.",negative regulation of cholangiocyte apoptotic process,biological_process
92286,GO:1904194,"Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.",positive regulation of cholangiocyte apoptotic process,biological_process
92287,GO:1904195,"Any process that modulates the frequency, rate or extent of granulosa cell proliferation.",regulation of granulosa cell proliferation,biological_process
92288,GO:1904196,"Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.",negative regulation of granulosa cell proliferation,biological_process
92289,GO:1904197,"Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.",positive regulation of granulosa cell proliferation,biological_process
92290,GO:1904198,"Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.",negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization,biological_process
92291,GO:1904199,"Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.",positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization,biological_process
92292,GO:1904200,The process in which iodide is transported across a membrane.,iodide transmembrane transport,biological_process
92293,GO:1904201,"Any process that modulates the frequency, rate or extent of iodide transport.",regulation of iodide transport,biological_process
92294,GO:1904202,"Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.",negative regulation of iodide transport,biological_process
92295,GO:1904203,"Any process that activates or increases the frequency, rate or extent of iodide transport.",positive regulation of iodide transport,biological_process
92296,GO:1904204,"Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.",regulation of skeletal muscle hypertrophy,biological_process
92297,GO:1904205,"Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.",negative regulation of skeletal muscle hypertrophy,biological_process
92298,GO:1904206,"Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.",positive regulation of skeletal muscle hypertrophy,biological_process
92299,GO:1904210,"The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.",VCP-NPL4-UFD1 AAA ATPase complex assembly,biological_process
92300,GO:1904212,"Any process that modulates the frequency, rate or extent of iodide transmembrane transport.",regulation of iodide transmembrane transport,biological_process
92301,GO:1904213,"Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport.",negative regulation of iodide transmembrane transport,biological_process
92302,GO:1904214,"Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.",positive regulation of iodide transmembrane transport,biological_process
92303,GO:1904215,"Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.",regulation of protein import into chloroplast stroma,biological_process
92304,GO:1904216,"Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.",positive regulation of protein import into chloroplast stroma,biological_process
92305,GO:1904222,"Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.",positive regulation of serine C-palmitoyltransferase activity,biological_process
92306,GO:1904231,"Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity.",positive regulation of succinate dehydrogenase activity,biological_process
92307,GO:1904235,"Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.","regulation of substrate-dependent cell migration, cell attachment to substrate",biological_process
92308,GO:1904236,"Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.","negative regulation of substrate-dependent cell migration, cell attachment to substrate",biological_process
92309,GO:1904237,"Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.","positive regulation of substrate-dependent cell migration, cell attachment to substrate",biological_process
92310,GO:1904238,The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.,pericyte cell differentiation,biological_process
92311,GO:1904239,"Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.",regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly,biological_process
92312,GO:1904240,"Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.",negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly,biological_process
92313,GO:1904241,"Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.",positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly,biological_process
92314,GO:1904242,"Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.",regulation of pancreatic trypsinogen secretion,biological_process
92315,GO:1904243,"Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.",negative regulation of pancreatic trypsinogen secretion,biological_process
92316,GO:1904244,"Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.",positive regulation of pancreatic trypsinogen secretion,biological_process
92317,GO:1904246,"Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.",negative regulation of polynucleotide adenylyltransferase activity,biological_process
92318,GO:1904247,"Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.",positive regulation of polynucleotide adenylyltransferase activity,biological_process
92319,GO:1904248,Any process that modulates the extent of age-related resistance.,regulation of age-related resistance,biological_process
92320,GO:1904249,"Any process that stops, prevents or reduces the extent of age-related resistance.",negative regulation of age-related resistance,biological_process
92321,GO:1904250,Any process that activates or increases the extent of age-related resistance.,positive regulation of age-related resistance,biological_process
92322,GO:1904257,The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi lumen.,zinc ion import into Golgi lumen,biological_process
92323,GO:1904258,"The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.",nuclear dicing body assembly,biological_process
92324,GO:1904262,"Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.",negative regulation of TORC1 signaling,biological_process
92325,GO:1904263,"Any process that activates or increases the frequency, rate or extent of TORC1 signaling.",positive regulation of TORC1 signaling,biological_process
92326,GO:1904266,"Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.",regulation of Schwann cell chemotaxis,biological_process
92327,GO:1904267,"Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.",negative regulation of Schwann cell chemotaxis,biological_process
92328,GO:1904268,"Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.",positive regulation of Schwann cell chemotaxis,biological_process
92329,GO:1904269,The cell cortex of the leading edge of a cell.,cell leading edge cell cortex,cellular_component
92330,GO:1904270,"The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex.",pyroptosome complex assembly,biological_process
92331,GO:1904271,"The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol.",L-proline import across plasma membrane,biological_process
92332,GO:1904272,"The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol.",L-tryptophan import across plasma membrane,biological_process
92333,GO:1904273,The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol.,L-alanine import across plasma membrane,biological_process
92334,GO:1904274,"The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.",tricellular tight junction assembly,biological_process
92335,GO:1904275,The disaggregation of a tricellular tight junction into its constituent components.,tricellular tight junction disassembly,biological_process
92336,GO:1904276,"Any process that modulates the frequency, rate or extent of wax biosynthetic process.",regulation of wax biosynthetic process,biological_process
92337,GO:1904277,"Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.",negative regulation of wax biosynthetic process,biological_process
92338,GO:1904278,"Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.",positive regulation of wax biosynthetic process,biological_process
92339,GO:1904279,"Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V.",regulation of transcription by RNA polymerase V,biological_process
92340,GO:1904280,"Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.",negative regulation of transcription by RNA polymerase V,biological_process
92341,GO:1904281,"Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V.",positive regulation of transcription by RNA polymerase V,biological_process
92342,GO:1904282,"Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.",regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I,biological_process
92343,GO:1904283,"Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.",negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I,biological_process
92344,GO:1904284,"Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.",positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I,biological_process
92345,GO:1904285,"Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.",regulation of protein-pyridoxal-5-phosphate linkage,biological_process
92346,GO:1904286,"Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.",negative regulation of protein-pyridoxal-5-phosphate linkage,biological_process
92347,GO:1904287,"Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.",positive regulation of protein-pyridoxal-5-phosphate linkage,biological_process
92348,GO:1904288,Binding to a BAT3 complex.,BAT3 complex binding,molecular_function
92349,GO:1904289,"Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.",regulation of mitotic DNA damage checkpoint,biological_process
92350,GO:1904290,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.",negative regulation of mitotic DNA damage checkpoint,biological_process
92351,GO:1904291,"Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.",positive regulation of mitotic DNA damage checkpoint,biological_process
92352,GO:1904292,"Any process that modulates the frequency, rate or extent of ERAD pathway.",regulation of ERAD pathway,biological_process
92353,GO:1904293,"Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.",negative regulation of ERAD pathway,biological_process
92354,GO:1904294,"Any process that activates or increases the frequency, rate or extent of ERAD pathway.",positive regulation of ERAD pathway,biological_process
92355,GO:1904298,"Any process that modulates the frequency, rate or extent of transcytosis.",regulation of transcytosis,biological_process
92356,GO:1904299,"Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis.",negative regulation of transcytosis,biological_process
92357,GO:1904300,"Any process that activates or increases the frequency, rate or extent of transcytosis.",positive regulation of transcytosis,biological_process
92358,GO:1904304,"Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.",regulation of gastro-intestinal system smooth muscle contraction,biological_process
92359,GO:1904305,"Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.",negative regulation of gastro-intestinal system smooth muscle contraction,biological_process
92360,GO:1904306,"Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.",positive regulation of gastro-intestinal system smooth muscle contraction,biological_process
92361,GO:1904307,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.",response to desipramine,biological_process
92362,GO:1904308,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.",cellular response to desipramine,biological_process
92363,GO:1904309,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.",response to cordycepin,biological_process
92364,GO:1904310,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.",cellular response to cordycepin,biological_process
92365,GO:1904311,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.",response to gold(3+),biological_process
92366,GO:1904312,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.",cellular response to gold(3+),biological_process
92367,GO:1904313,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.",response to methamphetamine hydrochloride,biological_process
92368,GO:1904314,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.",cellular response to methamphetamine hydrochloride,biological_process
92369,GO:1904315,Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.,transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential,molecular_function
92370,GO:1904316,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.",response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine,biological_process
92371,GO:1904317,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.",cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine,biological_process
92372,GO:1904321,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.",response to forskolin,biological_process
92373,GO:1904322,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.",cellular response to forskolin,biological_process
92374,GO:1904323,"Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.",regulation of inhibitory G protein-coupled receptor phosphorylation,biological_process
92375,GO:1904324,"Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.",negative regulation of inhibitory G protein-coupled receptor phosphorylation,biological_process
92376,GO:1904325,"Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.",positive regulation of inhibitory G protein-coupled receptor phosphorylation,biological_process
92377,GO:1904326,"Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness.","negative regulation of circadian sleep/wake cycle, wakefulness",biological_process
92378,GO:1904327,"A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.",protein localization to cytosolic proteasome complex,biological_process
92379,GO:1904328,"Any process that modulates the frequency, rate or extent of myofibroblast contraction.",regulation of myofibroblast contraction,biological_process
92380,GO:1904329,"Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction.",negative regulation of myofibroblast contraction,biological_process
92381,GO:1904330,"Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.",positive regulation of myofibroblast contraction,biological_process
92382,GO:1904331,"Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.",regulation of error-prone translesion synthesis,biological_process
92383,GO:1904332,"Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.",negative regulation of error-prone translesion synthesis,biological_process
92384,GO:1904333,"Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.",positive regulation of error-prone translesion synthesis,biological_process
92385,GO:1904334,"The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol.",heme import across plasma membrane,biological_process
92386,GO:1904335,"Any process that modulates the frequency, rate or extent of ductus arteriosus closure.",regulation of ductus arteriosus closure,biological_process
92387,GO:1904336,"Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.",negative regulation of ductus arteriosus closure,biological_process
92388,GO:1904337,"Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure.",positive regulation of ductus arteriosus closure,biological_process
92389,GO:1904338,"Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.",regulation of dopaminergic neuron differentiation,biological_process
92390,GO:1904339,"Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.",negative regulation of dopaminergic neuron differentiation,biological_process
92391,GO:1904340,"Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.",positive regulation of dopaminergic neuron differentiation,biological_process
92392,GO:1904341,"Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.",regulation of colon smooth muscle contraction,biological_process
92393,GO:1904342,"Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.",negative regulation of colon smooth muscle contraction,biological_process
92394,GO:1904343,"Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.",positive regulation of colon smooth muscle contraction,biological_process
92395,GO:1904344,"Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.",regulation of gastric mucosal blood circulation,biological_process
92396,GO:1904345,"Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.",negative regulation of gastric mucosal blood circulation,biological_process
92397,GO:1904346,"Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.",positive regulation of gastric mucosal blood circulation,biological_process
92398,GO:1904347,"Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.",regulation of small intestine smooth muscle contraction,biological_process
92399,GO:1904348,"Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.",negative regulation of small intestine smooth muscle contraction,biological_process
92400,GO:1904349,"Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.",positive regulation of small intestine smooth muscle contraction,biological_process
92401,GO:1904350,"Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.",regulation of protein catabolic process in the vacuole,biological_process
92402,GO:1904351,"Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.",negative regulation of protein catabolic process in the vacuole,biological_process
92403,GO:1904352,"Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.",positive regulation of protein catabolic process in the vacuole,biological_process
92404,GO:1904353,"Any process that modulates the frequency, rate or extent of telomere capping.",regulation of telomere capping,biological_process
92405,GO:1904354,"Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.",negative regulation of telomere capping,biological_process
92406,GO:1904355,"Any process that activates or increases the frequency, rate or extent of telomere capping.",positive regulation of telomere capping,biological_process
92407,GO:1904356,"Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.",regulation of telomere maintenance via telomere lengthening,biological_process
92408,GO:1904357,"Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.",negative regulation of telomere maintenance via telomere lengthening,biological_process
92409,GO:1904358,"Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.",positive regulation of telomere maintenance via telomere lengthening,biological_process
92410,GO:1904359,"Any process that modulates the frequency, rate or extent of spore germination.",regulation of spore germination,biological_process
92411,GO:1904360,"Any process that stops, prevents or reduces the frequency, rate or extent of spore germination.",negative regulation of spore germination,biological_process
92412,GO:1904361,"Any process that activates or increases the frequency, rate or extent of spore germination.",positive regulation of spore germination,biological_process
92413,GO:1904362,"Any process that modulates the frequency, rate or extent of calcitonin secretion.",regulation of calcitonin secretion,biological_process
92414,GO:1904363,"Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.",negative regulation of calcitonin secretion,biological_process
92415,GO:1904364,"Any process that activates or increases the frequency, rate or extent of calcitonin secretion.",positive regulation of calcitonin secretion,biological_process
92416,GO:1904365,"Any process that modulates the frequency, rate or extent of chemokinesis.",regulation of chemokinesis,biological_process
92417,GO:1904366,"Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.",negative regulation of chemokinesis,biological_process
92418,GO:1904367,"Any process that activates or increases the frequency, rate or extent of chemokinesis.",positive regulation of chemokinesis,biological_process
92419,GO:1904368,"Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation.",regulation of sclerenchyma cell differentiation,biological_process
92420,GO:1904369,"Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation.",positive regulation of sclerenchyma cell differentiation,biological_process
92421,GO:1904370,"Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.",regulation of protein localization to actin cortical patch,biological_process
92422,GO:1904371,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.",negative regulation of protein localization to actin cortical patch,biological_process
92423,GO:1904372,"Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.",positive regulation of protein localization to actin cortical patch,biological_process
92424,GO:1904373,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.",response to kainic acid,biological_process
92425,GO:1904374,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.",cellular response to kainic acid,biological_process
92426,GO:1904375,"Any process that modulates the frequency, rate or extent of protein localization to cell periphery.",regulation of protein localization to cell periphery,biological_process
92427,GO:1904376,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.",negative regulation of protein localization to cell periphery,biological_process
92428,GO:1904377,"Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.",positive regulation of protein localization to cell periphery,biological_process
92429,GO:1904380,"Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).",endoplasmic reticulum mannose trimming,biological_process
92430,GO:1904381,"The trimming, in the Golgi apparatus, of the protein newly attached high-mannose-type N-glycans by mannosidases to produce paucimannose-type N-glycans.",Golgi apparatus N-glycan mannose trimming,biological_process
92431,GO:1904382,"The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).",mannose trimming involved in glycoprotein ERAD pathway,biological_process
92432,GO:1904383,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.",response to sodium phosphate,biological_process
92433,GO:1904384,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.",cellular response to sodium phosphate,biological_process
92434,GO:1904385,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.",cellular response to angiotensin,biological_process
92435,GO:1904386,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.",response to L-phenylalanine derivative,biological_process
92436,GO:1904387,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.",cellular response to L-phenylalanine derivative,biological_process
92437,GO:1904389,The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.,rod bipolar cell differentiation,biological_process
92438,GO:1904390,The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.,cone retinal bipolar cell differentiation,biological_process
92439,GO:1904391,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.",response to ciliary neurotrophic factor,biological_process
92440,GO:1904392,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.",cellular response to ciliary neurotrophic factor,biological_process
92441,GO:1904393,"Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.",regulation of skeletal muscle acetylcholine-gated channel clustering,biological_process
92442,GO:1904394,"Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.",negative regulation of skeletal muscle acetylcholine-gated channel clustering,biological_process
92443,GO:1904395,"Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.",positive regulation of skeletal muscle acetylcholine-gated channel clustering,biological_process
92444,GO:1904396,"Any process that modulates the frequency, rate or extent of neuromuscular junction development.",regulation of neuromuscular junction development,biological_process
92445,GO:1904397,"Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.",negative regulation of neuromuscular junction development,biological_process
92446,GO:1904398,"Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.",positive regulation of neuromuscular junction development,biological_process
92447,GO:1904399,Binding to heparan sulfate.,heparan sulfate binding,molecular_function
92448,GO:1904400,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.",response to Thyroid stimulating hormone,biological_process
92449,GO:1904401,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.",cellular response to Thyroid stimulating hormone,biological_process
92450,GO:1904402,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.",response to nocodazole,biological_process
92451,GO:1904403,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.",cellular response to nocodazole,biological_process
92452,GO:1904404,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.",response to formaldehyde,biological_process
92453,GO:1904405,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.",cellular response to formaldehyde,biological_process
92454,GO:1904408,Binding to melatonin.,melatonin binding,molecular_function
92455,GO:1904409,"Any process that modulates the frequency, rate or extent of secretory granule organization.",regulation of secretory granule organization,biological_process
92456,GO:1904410,"Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.",negative regulation of secretory granule organization,biological_process
92457,GO:1904411,"Any process that activates or increases the frequency, rate or extent of secretory granule organization.",positive regulation of secretory granule organization,biological_process
92458,GO:1904412,"Any process that modulates the frequency, rate or extent of cardiac ventricle development.",regulation of cardiac ventricle development,biological_process
92459,GO:1904413,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.",negative regulation of cardiac ventricle development,biological_process
92460,GO:1904414,"Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.",positive regulation of cardiac ventricle development,biological_process
92461,GO:1904415,"Any process that modulates the frequency, rate or extent of xenophagy.",regulation of xenophagy,biological_process
92462,GO:1904416,"Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.",negative regulation of xenophagy,biological_process
92463,GO:1904417,"Any process that activates or increases the frequency, rate or extent of xenophagy.",positive regulation of xenophagy,biological_process
92464,GO:1904418,"Any process that modulates the frequency, rate or extent of telomeric loop formation.",regulation of telomeric loop formation,biological_process
92465,GO:1904419,"Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation.",negative regulation of telomeric loop formation,biological_process
92466,GO:1904420,"Any process that activates or increases the frequency, rate or extent of telomeric loop formation.",positive regulation of telomeric loop formation,biological_process
92467,GO:1904421,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.",response to D-galactosamine,biological_process
92468,GO:1904422,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.",cellular response to D-galactosamine,biological_process
92469,GO:1904423,A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.,dehydrodolichyl diphosphate synthase complex,cellular_component
92470,GO:1904426,"Any process that activates or increases the frequency, rate or extent of GTP binding.",positive regulation of GTP binding,biological_process
92471,GO:1904427,"Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.",positive regulation of calcium ion transmembrane transport,biological_process
92472,GO:1904428,"Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation.",negative regulation of tubulin deacetylation,biological_process
92473,GO:1904429,"Any process that modulates the frequency, rate or extent of t-circle formation.",regulation of t-circle formation,biological_process
92474,GO:1904430,"Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.",negative regulation of t-circle formation,biological_process
92475,GO:1904431,"Any process that activates or increases the frequency, rate or extent of t-circle formation.",positive regulation of t-circle formation,biological_process
92476,GO:1904438,"Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.",regulation of iron ion import across plasma membrane,biological_process
92477,GO:1904439,"Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.",negative regulation of iron ion import across plasma membrane,biological_process
92478,GO:1904440,"Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.",positive regulation of iron ion import across plasma membrane,biological_process
92479,GO:1904441,"Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation.",regulation of thyroid gland epithelial cell proliferation,biological_process
92480,GO:1904442,"Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.",negative regulation of thyroid gland epithelial cell proliferation,biological_process
92481,GO:1904443,"Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation.",positive regulation of thyroid gland epithelial cell proliferation,biological_process
92482,GO:1904444,"Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier.",regulation of establishment of Sertoli cell barrier,biological_process
92483,GO:1904445,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.",negative regulation of establishment of Sertoli cell barrier,biological_process
92484,GO:1904446,"Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.",positive regulation of establishment of Sertoli cell barrier,biological_process
92485,GO:1904447,"The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol.",folate import across plasma membrane,biological_process
92486,GO:1904448,"Any process that modulates the frequency, rate or extent of aspartate secretion.",regulation of aspartate secretion,biological_process
92487,GO:1904449,"Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.",negative regulation of aspartate secretion,biological_process
92488,GO:1904450,"Any process that activates or increases the frequency, rate or extent of aspartate secretion.",positive regulation of aspartate secretion,biological_process
92489,GO:1904451,"Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.",regulation of potassium:proton exchanging ATPase activity,biological_process
92490,GO:1904456,"Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.",negative regulation of neuronal action potential,biological_process
92491,GO:1904457,"Any process that activates or increases the frequency, rate or extent of neuronal action potential.",positive regulation of neuronal action potential,biological_process
92492,GO:1904458,"Any process that modulates the frequency, rate or extent of substance P secretion.",regulation of substance P secretion,biological_process
92493,GO:1904459,"Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.",negative regulation of substance P secretion,biological_process
92494,GO:1904460,"Any process that activates or increases the frequency, rate or extent of substance P secretion.",positive regulation of substance P secretion,biological_process
92495,GO:1904462,The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.,ergosteryl 3-beta-D-glucoside catabolic process,biological_process
92496,GO:1904463,The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.,ergosteryl 3-beta-D-glucoside biosynthetic process,biological_process
92497,GO:1904464,"Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.",regulation of matrix metallopeptidase secretion,biological_process
92498,GO:1904465,"Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.",negative regulation of matrix metallopeptidase secretion,biological_process
92499,GO:1904466,"Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.",positive regulation of matrix metallopeptidase secretion,biological_process
92500,GO:1904470,"Any process that modulates the frequency, rate or extent of endothelin production.",regulation of endothelin production,biological_process
92501,GO:1904471,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production.",negative regulation of endothelin production,biological_process
92502,GO:1904472,"Any process that activates or increases the frequency, rate or extent of endothelin production.",positive regulation of endothelin production,biological_process
92503,GO:1904473,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.",response to L-dopa,biological_process
92504,GO:1904474,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.",cellular response to L-dopa,biological_process
92505,GO:1904478,"Any process that modulates the frequency, rate or extent of intestinal absorption.",regulation of intestinal absorption,biological_process
92506,GO:1904479,"Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.",negative regulation of intestinal absorption,biological_process
92507,GO:1904480,"Any process that activates or increases the frequency, rate or extent of intestinal absorption.",positive regulation of intestinal absorption,biological_process
92508,GO:1904481,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.",response to tetrahydrofolate,biological_process
92509,GO:1904482,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.",cellular response to tetrahydrofolate,biological_process
92510,GO:1904483,Binding to synthetic cannabinoid.,synthetic cannabinoid binding,molecular_function
92511,GO:1904484,"The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.",cloacal gland development,biological_process
92512,GO:1904491,"A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.",protein localization to ciliary transition zone,biological_process
92513,GO:1904492,Binding to Ac-Asp-Glu.,Ac-Asp-Glu binding,molecular_function
92514,GO:1904493,Binding to tetrahydrofolyl-poly(glutamate) polymer.,tetrahydrofolyl-poly(glutamate) polymer binding,molecular_function
92515,GO:1904494,"Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission.","regulation of substance P secretion, neurotransmission",biological_process
92516,GO:1904495,"Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.","negative regulation of substance P secretion, neurotransmission",biological_process
92517,GO:1904496,"Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.","positive regulation of substance P secretion, neurotransmission",biological_process
92518,GO:1904498,Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.,protein localization to mitotic actomyosin contractile ring,biological_process
92519,GO:1904502,"Any process that modulates the frequency, rate or extent of lipophagy.",regulation of lipophagy,biological_process
92520,GO:1904503,"Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.",negative regulation of lipophagy,biological_process
92521,GO:1904504,"Any process that activates or increases the frequency, rate or extent of lipophagy.",positive regulation of lipophagy,biological_process
92522,GO:1904505,"Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.",regulation of telomere maintenance in response to DNA damage,biological_process
92523,GO:1904506,"Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.",negative regulation of telomere maintenance in response to DNA damage,biological_process
92524,GO:1904507,"Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.",positive regulation of telomere maintenance in response to DNA damage,biological_process
92525,GO:1904508,"Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.",regulation of protein localization to basolateral plasma membrane,biological_process
92526,GO:1904509,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.",negative regulation of protein localization to basolateral plasma membrane,biological_process
92527,GO:1904510,"Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.",positive regulation of protein localization to basolateral plasma membrane,biological_process
92528,GO:1904511,Any microtubule plus-end that is part of a cytoplasmic microtubule.,cytoplasmic microtubule plus-end,cellular_component
92529,GO:1904512,"Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.",regulation of initiation of premeiotic DNA replication,biological_process
92530,GO:1904513,"Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.",negative regulation of initiation of premeiotic DNA replication,biological_process
92531,GO:1904514,"Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.",positive regulation of initiation of premeiotic DNA replication,biological_process
92532,GO:1904515,"Any process that activates or increases the frequency, rate or extent of TORC2 signaling.",positive regulation of TORC2 signaling,biological_process
92533,GO:1904516,Any apoptotic process in a myofibroblast cell.,myofibroblast cell apoptotic process,biological_process
92534,GO:1904518,"A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.",protein localization to cytoplasmic microtubule plus-end,biological_process
92535,GO:1904519,"A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.",protein localization to microtubule minus-end,biological_process
92536,GO:1904520,"Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.",regulation of myofibroblast cell apoptotic process,biological_process
92537,GO:1904521,"Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process.",negative regulation of myofibroblast cell apoptotic process,biological_process
92538,GO:1904522,"Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process.",positive regulation of myofibroblast cell apoptotic process,biological_process
92539,GO:1904523,"Any process that modulates the frequency, rate or extent of DNA amplification.",regulation of DNA amplification,biological_process
92540,GO:1904524,"Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.",negative regulation of DNA amplification,biological_process
92541,GO:1904525,"Any process that activates or increases the frequency, rate or extent of DNA amplification.",positive regulation of DNA amplification,biological_process
92542,GO:1904530,"Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.",negative regulation of actin filament binding,biological_process
92543,GO:1904531,"Any process that activates or increases the frequency, rate or extent of actin filament binding.",positive regulation of actin filament binding,biological_process
92544,GO:1904533,"Any process that modulates the frequency, rate or extent of telomeric loop disassembly.",regulation of telomeric loop disassembly,biological_process
92545,GO:1904534,"Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.",negative regulation of telomeric loop disassembly,biological_process
92546,GO:1904535,"Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.",positive regulation of telomeric loop disassembly,biological_process
92547,GO:1904536,"Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.",regulation of mitotic telomere tethering at nuclear periphery,biological_process
92548,GO:1904537,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.",negative regulation of mitotic telomere tethering at nuclear periphery,biological_process
92549,GO:1904539,"Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.",negative regulation of glycolytic process through fructose-6-phosphate,biological_process
92550,GO:1904540,"Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.",positive regulation of glycolytic process through fructose-6-phosphate,biological_process
92551,GO:1904541,"Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion, where the cell wall is locally disassembled to enable conjugation with cellular fusion.",mating projection tip cell wall disassembly,biological_process
92552,GO:1904542,"Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.",regulation of free ubiquitin chain polymerization,biological_process
92553,GO:1904543,"Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization.",negative regulation of free ubiquitin chain polymerization,biological_process
92554,GO:1904544,"Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.",positive regulation of free ubiquitin chain polymerization,biological_process
92555,GO:1904547,"Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.",regulation of cellular response to glucose starvation,biological_process
92556,GO:1904550,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.",response to arachidonate,biological_process
92557,GO:1904551,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.",cellular response to arachidonate,biological_process
92558,GO:1904552,"Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid.",regulation of chemotaxis to arachidonate,biological_process
92559,GO:1904553,"Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid.",negative regulation of chemotaxis to arachidonate,biological_process
92560,GO:1904554,"Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.",positive regulation of chemotaxis to arachidonate,biological_process
92561,GO:1904555,The directed movement of L-proline across a membrane.,L-proline transmembrane transport,biological_process
92562,GO:1904556,The directed movement of L-tryptophan across a membrane.,L-tryptophan transmembrane transport,biological_process
92563,GO:1904557,The directed movement of L-alanine across a membrane by means of some agent such as a transporter or a pore.,L-alanine transmembrane transport,biological_process
92564,GO:1904558,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.",response to dextromethorphan,biological_process
92565,GO:1904559,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.",cellular response to dextromethorphan,biological_process
92566,GO:1904560,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.",response to diphenidol,biological_process
92567,GO:1904561,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.",cellular response to diphenidol,biological_process
92568,GO:1904562,The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.,phosphatidylinositol 5-phosphate metabolic process,biological_process
92569,GO:1904563,The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate.,phosphatidylinositol 5-phosphate biosynthetic process,biological_process
92570,GO:1904564,"A heterotetrameric complex with weak ATPase activity that is capable of scaffolding a 4Fe-4S (iron-sulfur) cluster. In yeast, the subunits are Nbp35 and Cfd1. In humans, the subunits are NUBP1 and NUBP2.",cytosolic [4Fe-4S] assembly scaffold complex,cellular_component
92571,GO:1904565,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.",response to 1-oleoyl-sn-glycerol 3-phosphate,biological_process
92572,GO:1904566,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.",cellular response to 1-oleoyl-sn-glycerol 3-phosphate,biological_process
92573,GO:1904567,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.",response to wortmannin,biological_process
92574,GO:1904568,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.",cellular response to wortmannin,biological_process
92575,GO:1904569,"Any process that modulates the frequency, rate or extent of selenocysteine incorporation.",regulation of selenocysteine incorporation,biological_process
92576,GO:1904570,"Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation.",negative regulation of selenocysteine incorporation,biological_process
92577,GO:1904571,"Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation.",positive regulation of selenocysteine incorporation,biological_process
92578,GO:1904580,"Any process that modulates the frequency, rate or extent of intracellular mRNA localization.",regulation of intracellular mRNA localization,biological_process
92579,GO:1904581,"Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.",negative regulation of intracellular mRNA localization,biological_process
92580,GO:1904582,"Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.",positive regulation of intracellular mRNA localization,biological_process
92581,GO:1904583,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.",response to polyamine macromolecule,biological_process
92582,GO:1904584,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.",cellular response to polyamine macromolecule,biological_process
92583,GO:1904585,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.",response to putrescine,biological_process
92584,GO:1904586,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.",cellular response to putrescine,biological_process
92585,GO:1904587,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.",response to glycoprotein,biological_process
92586,GO:1904588,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.",cellular response to glycoprotein,biological_process
92587,GO:1904589,"Any process that modulates the frequency, rate or extent of protein import.",regulation of protein import,biological_process
92588,GO:1904590,"Any process that stops, prevents or reduces the frequency, rate or extent of protein import.",negative regulation of protein import,biological_process
92589,GO:1904591,"Any process that activates or increases the frequency, rate or extent of protein import.",positive regulation of protein import,biological_process
92590,GO:1904592,"Any process that activates or increases the frequency, rate or extent of protein refolding.",positive regulation of protein refolding,biological_process
92591,GO:1904593,Binding to prostaglandin.,prostaglandin binding,molecular_function
92592,GO:1904594,"Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.",regulation of termination of RNA polymerase II transcription,biological_process
92593,GO:1904595,"Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.",positive regulation of termination of RNA polymerase II transcription,biological_process
92594,GO:1904597,"Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response.",negative regulation of connective tissue replacement involved in inflammatory response wound healing,biological_process
92595,GO:1904598,"Any process that activates or increases the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response.",positive regulation of connective tissue replacement involved in inflammatory response wound healing,biological_process
92596,GO:1904599,Binding to advanced glycation end-product.,advanced glycation end-product binding,molecular_function
92597,GO:1904600,"The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus.",mating projection actin fusion focus assembly,biological_process
92598,GO:1904601,A process in which a protein is transported to a location within an actin fusion focus.,protein transport to mating projection actin fusion focus,biological_process
92599,GO:1904602,"A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.",serotonin-activated cation-selective channel complex,cellular_component
92600,GO:1904606,Any apoptotic process in a fat cell.,fat cell apoptotic process,biological_process
92601,GO:1904610,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.","response to 3,3',4,4',5-pentachlorobiphenyl",biological_process
92602,GO:1904611,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.","cellular response to 3,3',4,4',5-pentachlorobiphenyl",biological_process
92603,GO:1904612,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.","response to 2,3,7,8-tetrachlorodibenzodioxine",biological_process
92604,GO:1904613,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.","cellular response to 2,3,7,8-tetrachlorodibenzodioxine",biological_process
92605,GO:1904614,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.",response to biphenyl,biological_process
92606,GO:1904615,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.",cellular response to biphenyl,biological_process
92607,GO:1904619,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.",response to dimethyl sulfoxide,biological_process
92608,GO:1904620,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.",cellular response to dimethyl sulfoxide,biological_process
92609,GO:1904624,"Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission.","regulation of glycine secretion, neurotransmission",biological_process
92610,GO:1904625,"Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.","negative regulation of glycine secretion, neurotransmission",biological_process
92611,GO:1904626,"Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission.","positive regulation of glycine secretion, neurotransmission",biological_process
92612,GO:1904627,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.",response to phorbol 13-acetate 12-myristate,biological_process
92613,GO:1904628,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.",cellular response to phorbol 13-acetate 12-myristate,biological_process
92614,GO:1904629,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.",response to diterpene,biological_process
92615,GO:1904630,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.",cellular response to diterpene,biological_process
92616,GO:1904631,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.",response to glucoside,biological_process
92617,GO:1904632,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.",cellular response to glucoside,biological_process
92618,GO:1904633,"Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.",regulation of podocyte apoptotic process,biological_process
92619,GO:1904634,"Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.",negative regulation of podocyte apoptotic process,biological_process
92620,GO:1904635,"Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.",positive regulation of podocyte apoptotic process,biological_process
92621,GO:1904636,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.",response to ionomycin,biological_process
92622,GO:1904637,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.",cellular response to ionomycin,biological_process
92623,GO:1904638,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.",response to resveratrol,biological_process
92624,GO:1904639,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.",cellular response to resveratrol,biological_process
92625,GO:1904640,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.",response to methionine,biological_process
92626,GO:1904641,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.",response to dinitrophenol,biological_process
92627,GO:1904642,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.",cellular response to dinitrophenol,biological_process
92628,GO:1904643,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.",response to curcumin,biological_process
92629,GO:1904644,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.",cellular response to curcumin,biological_process
92630,GO:1904645,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.",response to amyloid-beta,biological_process
92631,GO:1904646,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.",cellular response to amyloid-beta,biological_process
92632,GO:1904647,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.",response to rotenone,biological_process
92633,GO:1904648,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.",cellular response to rotenone,biological_process
92634,GO:1904649,"Any process that modulates the frequency, rate or extent of fat cell apoptotic process.",regulation of fat cell apoptotic process,biological_process
92635,GO:1904650,"Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.",negative regulation of fat cell apoptotic process,biological_process
92636,GO:1904651,"Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.",positive regulation of fat cell apoptotic process,biological_process
92637,GO:1904653,"Any process that modulates the frequency, rate or extent of lung alveolus development.",regulation of lung alveolus development,biological_process
92638,GO:1904654,"Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.",negative regulation of lung alveolus development,biological_process
92639,GO:1904655,"Any process that activates or increases the frequency, rate or extent of lung alveolus development.",positive regulation of lung alveolus development,biological_process
92640,GO:1904656,"Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.",regulation of sensory perception of sweet taste,biological_process
92641,GO:1904657,"Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste.",negative regulation of sensory perception of sweet taste,biological_process
92642,GO:1904658,"Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.",positive regulation of sensory perception of sweet taste,biological_process
92643,GO:1904659,The process in which D-glucose is transported across a membrane.,D-glucose transmembrane transport,biological_process
92644,GO:1904660,"Any process that modulates the frequency, rate or extent of sensory perception of bitter taste.",regulation of sensory perception of bitter taste,biological_process
92645,GO:1904661,"Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.",negative regulation of sensory perception of bitter taste,biological_process
92646,GO:1904662,"Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste.",positive regulation of sensory perception of bitter taste,biological_process
92647,GO:1904663,"Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.",regulation of N-terminal peptidyl-methionine acetylation,biological_process
92648,GO:1904664,"Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.",negative regulation of N-terminal peptidyl-methionine acetylation,biological_process
92649,GO:1904665,"Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.",positive regulation of N-terminal peptidyl-methionine acetylation,biological_process
92650,GO:1904666,"Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity.",regulation of ubiquitin protein ligase activity,biological_process
92651,GO:1904667,"Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.",negative regulation of ubiquitin protein ligase activity,biological_process
92652,GO:1904668,"Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.",positive regulation of ubiquitin protein ligase activity,biological_process
92653,GO:1904669,The directed movement of ATP out of a cell or organelle.,ATP export,biological_process
92654,GO:1904672,"Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.",regulation of somatic stem cell population maintenance,biological_process
92655,GO:1904673,"Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.",negative regulation of somatic stem cell population maintenance,biological_process
92656,GO:1904674,"Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.",positive regulation of somatic stem cell population maintenance,biological_process
92657,GO:1904675,"Any process that modulates the frequency, rate or extent of somatic stem cell division.",regulation of somatic stem cell division,biological_process
92658,GO:1904676,"Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.",negative regulation of somatic stem cell division,biological_process
92659,GO:1904677,"Any process that activates or increases the frequency, rate or extent of somatic stem cell division.",positive regulation of somatic stem cell division,biological_process
92660,GO:1904678,Binding to an alpha-aminoacyl-tRNA.,alpha-aminoacyl-tRNA binding,molecular_function
92661,GO:1904679,"The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol.",myo-inositol import across plasma membrane,biological_process
92662,GO:1904680,Enables the transfer of a peptide from one side of a membrane to the other.,peptide transmembrane transporter activity,molecular_function
92663,GO:1904681,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.",response to 3-methylcholanthrene,biological_process
92664,GO:1904682,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.",cellular response to 3-methylcholanthrene,biological_process
92665,GO:1904685,"Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity.",positive regulation of metalloendopeptidase activity,biological_process
92666,GO:1904686,"Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.",regulation of mitotic spindle disassembly,biological_process
92667,GO:1904687,"Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.",positive regulation of mitotic spindle disassembly,biological_process
92668,GO:1904688,"Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.",regulation of cytoplasmic translational initiation,biological_process
92669,GO:1904689,"Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.",negative regulation of cytoplasmic translational initiation,biological_process
92670,GO:1904690,"Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.",positive regulation of cytoplasmic translational initiation,biological_process
92671,GO:1904691,"Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.",negative regulation of type B pancreatic cell proliferation,biological_process
92672,GO:1904692,"Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.",positive regulation of type B pancreatic cell proliferation,biological_process
92673,GO:1904693,The developmental process by which a midbrain is generated and organized.,midbrain morphogenesis,biological_process
92674,GO:1904694,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction.",negative regulation of vascular associated smooth muscle contraction,biological_process
92675,GO:1904695,"Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction.",positive regulation of vascular associated smooth muscle contraction,biological_process
92676,GO:1904697,"Any process that modulates the frequency, rate or extent of acinar cell proliferation.",regulation of acinar cell proliferation,biological_process
92677,GO:1904698,"Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.",negative regulation of acinar cell proliferation,biological_process
92678,GO:1904699,"Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.",positive regulation of acinar cell proliferation,biological_process
92679,GO:1904700,Any apoptotic process in a granulosa cell.,granulosa cell apoptotic process,biological_process
92680,GO:1904701,"The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.",Wnt-Frizzled-LRP5/6 complex assembly,biological_process
92681,GO:1904702,"Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.",regulation of protein localization to adherens junction,biological_process
92682,GO:1904703,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.",negative regulation of protein localization to adherens junction,biological_process
92683,GO:1904704,"Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.",positive regulation of protein localization to adherens junction,biological_process
92684,GO:1904705,"Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.",regulation of vascular associated smooth muscle cell proliferation,biological_process
92685,GO:1904706,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.",negative regulation of vascular associated smooth muscle cell proliferation,biological_process
92686,GO:1904707,"Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.",positive regulation of vascular associated smooth muscle cell proliferation,biological_process
92687,GO:1904708,"Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.",regulation of granulosa cell apoptotic process,biological_process
92688,GO:1904709,"Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.",negative regulation of granulosa cell apoptotic process,biological_process
92689,GO:1904710,"Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.",positive regulation of granulosa cell apoptotic process,biological_process
92690,GO:1904711,"Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.",regulation of Wnt-Frizzled-LRP5/6 complex assembly,biological_process
92691,GO:1904712,"Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.",positive regulation of Wnt-Frizzled-LRP5/6 complex assembly,biological_process
92692,GO:1904713,Binding to a beta-catenin destruction complex.,beta-catenin destruction complex binding,molecular_function
92693,GO:1904714,"Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy.",regulation of chaperone-mediated autophagy,biological_process
92694,GO:1904715,"Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy.",negative regulation of chaperone-mediated autophagy,biological_process
92695,GO:1904716,"Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.",positive regulation of chaperone-mediated autophagy,biological_process
92696,GO:1904717,"Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.",regulation of AMPA glutamate receptor clustering,biological_process
92697,GO:1904718,"Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering.",negative regulation of AMPA glutamate receptor clustering,biological_process
92698,GO:1904719,"Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.",positive regulation of AMPA glutamate receptor clustering,biological_process
92699,GO:1904723,"Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.",negative regulation of Wnt-Frizzled-LRP5/6 complex assembly,biological_process
92700,GO:1904724,Any membrane-enclosed lumen that is part of a tertiary granule.,tertiary granule lumen,cellular_component
92701,GO:1904726,"Any process that modulates the frequency, rate or extent of replicative senescence.",regulation of replicative senescence,biological_process
92702,GO:1904727,"Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence.",negative regulation of replicative senescence,biological_process
92703,GO:1904728,"Any process that activates or increases the frequency, rate or extent of replicative senescence.",positive regulation of replicative senescence,biological_process
92704,GO:1904729,"Any process that modulates the frequency, rate or extent of intestinal lipid absorption.",regulation of intestinal lipid absorption,biological_process
92705,GO:1904730,"Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption.",negative regulation of intestinal lipid absorption,biological_process
92706,GO:1904731,"Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.",positive regulation of intestinal lipid absorption,biological_process
92707,GO:1904738,The orderly movement of a vascular associated smooth muscle cell from one site to another.,vascular associated smooth muscle cell migration,biological_process
92708,GO:1904745,"The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.",Atg1/ULK1 kinase complex assembly,biological_process
92709,GO:1904746,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.",negative regulation of apoptotic process involved in development,biological_process
92710,GO:1904747,"Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.",positive regulation of apoptotic process involved in development,biological_process
92711,GO:1904748,"Any process that modulates the frequency, rate or extent of apoptotic process involved in development.",regulation of apoptotic process involved in development,biological_process
92712,GO:1904749,"Any process that modulates the frequency, rate or extent of protein localization to nucleolus.",regulation of protein localization to nucleolus,biological_process
92713,GO:1904750,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.",negative regulation of protein localization to nucleolus,biological_process
92714,GO:1904751,"Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.",positive regulation of protein localization to nucleolus,biological_process
92715,GO:1904752,"Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.",regulation of vascular associated smooth muscle cell migration,biological_process
92716,GO:1904753,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.",negative regulation of vascular associated smooth muscle cell migration,biological_process
92717,GO:1904754,"Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.",positive regulation of vascular associated smooth muscle cell migration,biological_process
92718,GO:1904755,"Any process that modulates the frequency, rate or extent of gut granule assembly.",regulation of gut granule assembly,biological_process
92719,GO:1904756,"Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.",negative regulation of gut granule assembly,biological_process
92720,GO:1904757,"Any process that activates or increases the frequency, rate or extent of gut granule assembly.",positive regulation of gut granule assembly,biological_process
92721,GO:1904758,"A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.",protein localization to new growing cell tip,biological_process
92722,GO:1904759,"A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.",protein localization to equatorial microtubule organizing center,biological_process
92723,GO:1904760,"Any process that modulates the frequency, rate or extent of myofibroblast differentiation.",regulation of myofibroblast differentiation,biological_process
92724,GO:1904761,"Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.",negative regulation of myofibroblast differentiation,biological_process
92725,GO:1904762,"Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation.",positive regulation of myofibroblast differentiation,biological_process
92726,GO:1904763,"The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex.",chaperone-mediated autophagy translocation complex assembly,biological_process
92727,GO:1904764,The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.,chaperone-mediated autophagy translocation complex disassembly,biological_process
92728,GO:1904767,Binding to octanoic acid.,octanoic acid binding,molecular_function
92729,GO:1904768,Binding to all-trans-retinol.,all-trans-retinol binding,molecular_function
92730,GO:1904769,Binding to isopentadecanoic acid.,isopentadecanoic acid binding,molecular_function
92731,GO:1904770,The developmental process by which an intramembranous bone is generated and organized.,intramembranous bone morphogenesis,biological_process
92732,GO:1904772,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.",response to tetrachloromethane,biological_process
92733,GO:1904774,"Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process.",negative regulation of ubiquinone biosynthetic process,biological_process
92734,GO:1904775,"Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process.",positive regulation of ubiquinone biosynthetic process,biological_process
92735,GO:1904776,"Any process that modulates the frequency, rate or extent of protein localization to cell cortex.",regulation of protein localization to cell cortex,biological_process
92736,GO:1904777,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.",negative regulation of protein localization to cell cortex,biological_process
92737,GO:1904778,"Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.",positive regulation of protein localization to cell cortex,biological_process
92738,GO:1904779,"Any process that modulates the frequency, rate or extent of protein localization to centrosome.",regulation of protein localization to centrosome,biological_process
92739,GO:1904780,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.",negative regulation of protein localization to centrosome,biological_process
92740,GO:1904781,"Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.",positive regulation of protein localization to centrosome,biological_process
92741,GO:1904782,"Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.",negative regulation of NMDA glutamate receptor activity,biological_process
92742,GO:1904784,"The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.",NLRP1 inflammasome complex assembly,biological_process
92743,GO:1904785,"Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.",regulation of asymmetric protein localization involved in cell fate determination,biological_process
92744,GO:1904787,"Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.",positive regulation of asymmetric protein localization involved in cell fate determination,biological_process
92745,GO:1904790,"Any process that modulates the frequency, rate or extent of shelterin complex assembly.",regulation of shelterin complex assembly,biological_process
92746,GO:1904791,"Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly.",negative regulation of shelterin complex assembly,biological_process
92747,GO:1904792,"Any process that activates or increases the frequency, rate or extent of shelterin complex assembly.",positive regulation of shelterin complex assembly,biological_process
92748,GO:1904797,"Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.",negative regulation of core promoter binding,biological_process
92749,GO:1904798,"Any process that activates or increases the frequency, rate or extent of core promoter binding.",positive regulation of core promoter binding,biological_process
92750,GO:1904799,"Any process that modulates the frequency, rate or extent of neuron remodeling.",regulation of neuron remodeling,biological_process
92751,GO:1904800,"Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling.",negative regulation of neuron remodeling,biological_process
92752,GO:1904801,"Any process that activates or increases the frequency, rate or extent of neuron remodeling.",positive regulation of neuron remodeling,biological_process
92753,GO:1904802,"The aggregation, arrangement and bonding together of a set of components to form a RITS complex.",RITS complex assembly,biological_process
92754,GO:1904803,Any regulation of translation that is involved in cellular response to UV.,regulation of translation involved in cellular response to UV,biological_process
92755,GO:1904806,"Any process that modulates the frequency, rate or extent of protein oxidation.",regulation of protein oxidation,biological_process
92756,GO:1904807,"Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation.",negative regulation of protein oxidation,biological_process
92757,GO:1904808,"Any process that activates or increases the frequency, rate or extent of protein oxidation.",positive regulation of protein oxidation,biological_process
92758,GO:1904809,"Any process that modulates the frequency, rate or extent of dense core granule transport.",regulation of dense core granule transport,biological_process
92759,GO:1904810,"Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.",negative regulation of dense core granule transport,biological_process
92760,GO:1904811,"Any process that activates or increases the frequency, rate or extent of dense core granule transport.",positive regulation of dense core granule transport,biological_process
92761,GO:1904812,Any rRNA acetylation that is involved in maturation of SSU-rRNA.,rRNA acetylation involved in maturation of SSU-rRNA,biological_process
92762,GO:1904813,Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.,ficolin-1-rich granule lumen,cellular_component
92763,GO:1904814,"Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region.","regulation of protein localization to chromosome, telomeric region",biological_process
92764,GO:1904815,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region.","negative regulation of protein localization to chromosome, telomeric region",biological_process
92765,GO:1904816,"Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region.","positive regulation of protein localization to chromosome, telomeric region",biological_process
92766,GO:1904817,"The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.",serous membrane development,biological_process
92767,GO:1904818,"The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.",visceral peritoneum development,biological_process
92768,GO:1904819,"The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.",parietal peritoneum development,biological_process
92769,GO:1904820,"The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.",peritoneum development,biological_process
92770,GO:1904821,The disaggregation of a chloroplast into its constituent components.,chloroplast disassembly,biological_process
92771,GO:1904823,The process in which a purine nucleobase is transported across a membrane.,purine nucleobase transmembrane transport,biological_process
92772,GO:1904824,"The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex.",anaphase-promoting complex assembly,biological_process
92773,GO:1904825,"A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.",protein localization to microtubule plus-end,biological_process
92774,GO:1904826,"Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.",regulation of hydrogen sulfide biosynthetic process,biological_process
92775,GO:1904827,"Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.",negative regulation of hydrogen sulfide biosynthetic process,biological_process
92776,GO:1904828,"Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.",positive regulation of hydrogen sulfide biosynthetic process,biological_process
92777,GO:1904829,"Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.",regulation of aortic smooth muscle cell differentiation,biological_process
92778,GO:1904830,"Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.",negative regulation of aortic smooth muscle cell differentiation,biological_process
92779,GO:1904831,"Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.",positive regulation of aortic smooth muscle cell differentiation,biological_process
92780,GO:1904832,"Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.",negative regulation of removal of superoxide radicals,biological_process
92781,GO:1904833,"Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.",positive regulation of removal of superoxide radicals,biological_process
92782,GO:1904835,The developmental process by which a dorsal root ganglion is generated and organized.,dorsal root ganglion morphogenesis,biological_process
92783,GO:1904836,The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.,facioacoustic ganglion morphogenesis,biological_process
92784,GO:1904837,"The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.",beta-catenin-TCF complex assembly,biological_process
92785,GO:1904838,"Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.",regulation of male germ-line stem cell asymmetric division,biological_process
92786,GO:1904839,"Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.",negative regulation of male germ-line stem cell asymmetric division,biological_process
92787,GO:1904840,"Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division.",positive regulation of male germ-line stem cell asymmetric division,biological_process
92788,GO:1904841,Binding to a TORC2 complex.,TORC2 complex binding,molecular_function
92789,GO:1904842,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.",response to nitroglycerin,biological_process
92790,GO:1904843,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.",cellular response to nitroglycerin,biological_process
92791,GO:1904844,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.",response to L-glutamine,biological_process
92792,GO:1904845,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.",cellular response to L-glutamine,biological_process
92793,GO:1904846,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity.",negative regulation of establishment of bipolar cell polarity,biological_process
92794,GO:1904847,"Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.",regulation of cell chemotaxis to fibroblast growth factor,biological_process
92795,GO:1904848,"Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.",negative regulation of cell chemotaxis to fibroblast growth factor,biological_process
92796,GO:1904849,"Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.",positive regulation of cell chemotaxis to fibroblast growth factor,biological_process
92797,GO:1904850,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.",negative regulation of establishment of protein localization to telomere,biological_process
92798,GO:1904851,"Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.",positive regulation of establishment of protein localization to telomere,biological_process
92799,GO:1904852,A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity.,trimethylamine-N-oxide reductase (cytochrome c) complex,cellular_component
92800,GO:1904853,"A process in which a protein is transported to, or maintained in, a location within an ascospore wall.",protein localization to ascospore wall,biological_process
92801,GO:1904854,Binding to a proteasome core complex.,proteasome core complex binding,molecular_function
92802,GO:1904855,Binding to a proteasome regulatory particle.,proteasome regulatory particle binding,molecular_function
92803,GO:1904856,Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule.,cytolytic granule lumen,cellular_component
92804,GO:1904857,"Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.",regulation of endothelial cell chemotaxis to vascular endothelial growth factor,biological_process
92805,GO:1904858,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.",negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor,biological_process
92806,GO:1904859,"Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.",positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor,biological_process
92807,GO:1904860,Any DNA biosynthetic process that is involved in mitotic DNA replication.,DNA synthesis involved in mitotic DNA replication,biological_process
92808,GO:1904861,"The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.",excitatory synapse assembly,biological_process
92809,GO:1904862,"The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.",inhibitory synapse assembly,biological_process
92810,GO:1904863,"Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.",regulation of beta-catenin-TCF complex assembly,biological_process
92811,GO:1904864,"Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly.",negative regulation of beta-catenin-TCF complex assembly,biological_process
92812,GO:1904865,"Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.",positive regulation of beta-catenin-TCF complex assembly,biological_process
92813,GO:1904866,"The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.",ventral tegmental area development,biological_process
92814,GO:1904867,"A process in which a protein is transported to, or maintained in, a location within a Cajal body.",protein localization to Cajal body,biological_process
92815,GO:1904868,"The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.",telomerase catalytic core complex assembly,biological_process
92816,GO:1904869,"Any process that modulates the frequency, rate or extent of protein localization to Cajal body.",regulation of protein localization to Cajal body,biological_process
92817,GO:1904870,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.",negative regulation of protein localization to Cajal body,biological_process
92818,GO:1904871,"Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.",positive regulation of protein localization to Cajal body,biological_process
92819,GO:1904872,"Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.",regulation of telomerase RNA localization to Cajal body,biological_process
92820,GO:1904873,"Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.",negative regulation of telomerase RNA localization to Cajal body,biological_process
92821,GO:1904874,"Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.",positive regulation of telomerase RNA localization to Cajal body,biological_process
92822,GO:1904878,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.",negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel,biological_process
92823,GO:1904879,"Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.",positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel,biological_process
92824,GO:1904880,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.",response to hydrogen sulfide,biological_process
92825,GO:1904881,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.",cellular response to hydrogen sulfide,biological_process
92826,GO:1904882,"Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly.",regulation of telomerase catalytic core complex assembly,biological_process
92827,GO:1904883,"Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.",negative regulation of telomerase catalytic core complex assembly,biological_process
92828,GO:1904884,"Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly.",positive regulation of telomerase catalytic core complex assembly,biological_process
92829,GO:1904885,"The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.",beta-catenin destruction complex assembly,biological_process
92830,GO:1904886,The disaggregation of a beta-catenin destruction complex into its constituent components.,beta-catenin destruction complex disassembly,biological_process
92831,GO:1904887,"The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome.",Wnt signalosome assembly,biological_process
92832,GO:1904888,"The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.",cranial skeletal system development,biological_process
92833,GO:1904889,"Any process that modulates the frequency, rate or extent of excitatory synapse assembly.",regulation of excitatory synapse assembly,biological_process
92834,GO:1904890,"Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.",negative regulation of excitatory synapse assembly,biological_process
92835,GO:1904891,"Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.",positive regulation of excitatory synapse assembly,biological_process
92836,GO:1904892,"Any process that modulates the frequency, rate or extent of receptor signaling via STAT.",regulation of receptor signaling pathway via STAT,biological_process
92837,GO:1904893,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.",negative regulation of receptor signaling pathway via STAT,biological_process
92838,GO:1904894,"Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.",positive regulation of receptor signaling pathway via STAT,biological_process
92839,GO:1904895,"The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex.",ESCRT complex assembly,biological_process
92840,GO:1904896,The disaggregation of an ESCRT complex into its constituent components.,ESCRT complex disassembly,biological_process
92841,GO:1904897,"Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.",regulation of hepatic stellate cell proliferation,biological_process
92842,GO:1904898,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.",negative regulation of hepatic stellate cell proliferation,biological_process
92843,GO:1904899,"Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.",positive regulation of hepatic stellate cell proliferation,biological_process
92844,GO:1904900,"Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization.",negative regulation of myosin II filament organization,biological_process
92845,GO:1904901,"Any process that activates or increases the frequency, rate or extent of myosin II filament organization.",positive regulation of myosin II filament organization,biological_process
92846,GO:1904902,"The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex.",ESCRT III complex assembly,biological_process
92847,GO:1904903,The disaggregation of an ESCRT III complex into its constituent components.,ESCRT III complex disassembly,biological_process
92848,GO:1904904,"Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion.",regulation of endothelial cell-matrix adhesion,biological_process
92849,GO:1904905,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion.",negative regulation of endothelial cell-matrix adhesion,biological_process
92850,GO:1904906,"Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion.",positive regulation of endothelial cell-matrix adhesion,biological_process
92851,GO:1904907,"Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.","regulation of maintenance of mitotic sister chromatid cohesion, telomeric",biological_process
92852,GO:1904908,"Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.","negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric",biological_process
92853,GO:1904909,"Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.","positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric",biological_process
92854,GO:1904910,"Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.",regulation of establishment of RNA localization to telomere,biological_process
92855,GO:1904911,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere.",negative regulation of establishment of RNA localization to telomere,biological_process
92856,GO:1904912,"Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere.",positive regulation of establishment of RNA localization to telomere,biological_process
92857,GO:1904913,"Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.",regulation of establishment of protein-containing complex localization to telomere,biological_process
92858,GO:1904914,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.",negative regulation of establishment of protein-containing complex localization to telomere,biological_process
92859,GO:1904915,"Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.",positive regulation of establishment of protein-containing complex localization to telomere,biological_process
92860,GO:1904916,The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol.,L-lysine transmembrane transport from lysosomal lumen to cytosol,biological_process
92861,GO:1904917,The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol.,L-arginine transmembrane transport from lysosomal lumen to cytosol,biological_process
92862,GO:1904918,The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol.,L-histidine transmembrane transport from lysosomal lumen to cytosol,biological_process
92863,GO:1904919,The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol.,L-cystine transmembrane transport from lysosomal lumen to cytosol,biological_process
92864,GO:1904926,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.",response to palmitoleic acid,biological_process
92865,GO:1904927,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.",cellular response to palmitoleic acid,biological_process
92866,GO:1904930,Any membrane that is part of an amphisome.,amphisome membrane,cellular_component
92867,GO:1904931,Binding to an MCM complex.,MCM complex binding,molecular_function
92868,GO:1904932,"Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.",negative regulation of cartilage condensation,biological_process
92869,GO:1904933,"Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.",regulation of cell proliferation in midbrain,biological_process
92870,GO:1904934,"Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.",negative regulation of cell proliferation in midbrain,biological_process
92871,GO:1904935,"Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.",positive regulation of cell proliferation in midbrain,biological_process
92872,GO:1904936,The orderly movement of an interneuron from one site to another.,interneuron migration,biological_process
92873,GO:1904937,The orderly movement of a sensory neuron from one site to another.,sensory neuron migration,biological_process
92874,GO:1904942,"Any process that modulates the frequency, rate or extent of cardiac ventricle formation.",regulation of cardiac ventricle formation,biological_process
92875,GO:1904943,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.",negative regulation of cardiac ventricle formation,biological_process
92876,GO:1904944,"Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.",positive regulation of cardiac ventricle formation,biological_process
92877,GO:1904947,The process in which folic acid is transported from the cytosol into the mitochondrial matrix.,folate import into mitochondrion,biological_process
92878,GO:1904948,The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.,midbrain dopaminergic neuron differentiation,biological_process
92879,GO:1904949,A protein complex which is capable of ATPase activity.,ATPase complex,cellular_component
92880,GO:1904950,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.",negative regulation of establishment of protein localization,biological_process
92881,GO:1904951,"Any process that activates or increases the frequency, rate or extent of establishment of protein localization.",positive regulation of establishment of protein localization,biological_process
92882,GO:1904952,"The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hydroxycinnamic acid transport,biological_process
92883,GO:1904956,"Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.",regulation of midbrain dopaminergic neuron differentiation,biological_process
92884,GO:1904957,"Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.",negative regulation of midbrain dopaminergic neuron differentiation,biological_process
92885,GO:1904958,"Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.",positive regulation of midbrain dopaminergic neuron differentiation,biological_process
92886,GO:1904959,"Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.",regulation of cytochrome-c oxidase activity,biological_process
92887,GO:1904960,"Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.",positive regulation of cytochrome-c oxidase activity,biological_process
92888,GO:1904961,The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.,quiescent center organization,biological_process
92889,GO:1904962,The vesicle-mediated and directed movement of substances from plastid to vacuole.,plastid to vacuole vesicle-mediated transport,biological_process
92890,GO:1904963,"Any process that modulates the frequency, rate or extent of phytol biosynthetic process.",regulation of phytol biosynthetic process,biological_process
92891,GO:1904964,"Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.",positive regulation of phytol biosynthetic process,biological_process
92892,GO:1904965,"Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process.",regulation of vitamin E biosynthetic process,biological_process
92893,GO:1904966,"Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.",positive regulation of vitamin E biosynthetic process,biological_process
92894,GO:1904967,"Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.",regulation of spindle attachment to meiosis I kinetochore,biological_process
92895,GO:1904968,"Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.",positive regulation of spindle attachment to meiosis I kinetochore,biological_process
92896,GO:1904969,The orderly movement of a slow muscle cell from one site to another.,slow muscle cell migration,biological_process
92897,GO:1904970,"The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.",brush border assembly,biological_process
92898,GO:1904971,"Any process that modulates the frequency, rate or extent of viral translation.",regulation of viral translation,biological_process
92899,GO:1904972,"Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.",negative regulation of viral translation,biological_process
92900,GO:1904973,"Any process that activates or increases the frequency, rate or extent of viral translation.",positive regulation of viral translation,biological_process
92901,GO:1904974,A protein complex which is capable of heparanase activity.,heparanase complex,cellular_component
92902,GO:1904975,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.",response to bleomycin,biological_process
92903,GO:1904976,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.",cellular response to bleomycin,biological_process
92904,GO:1904977,The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.,lymphatic endothelial cell migration,biological_process
92905,GO:1904978,"Any process that modulates the frequency, rate or extent of endosome organization.",regulation of endosome organization,biological_process
92906,GO:1904979,"Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.",negative regulation of endosome organization,biological_process
92907,GO:1904980,"Any process that activates or increases the frequency, rate or extent of endosome organization.",positive regulation of endosome organization,biological_process
92908,GO:1904981,The process in which maltose is transported across a membrane.,maltose transmembrane transport,biological_process
92909,GO:1904982,The process in which sucrose is transported across a membrane.,sucrose transmembrane transport,biological_process
92910,GO:1904983,The process in which glycine is transported from the cytosol into the mitochondrial matrix.,glycine import into mitochondrion,biological_process
92911,GO:1904984,"Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.",regulation of quinolinate biosynthetic process,biological_process
92912,GO:1904985,"Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process.",negative regulation of quinolinate biosynthetic process,biological_process
92913,GO:1904986,"Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.",positive regulation of quinolinate biosynthetic process,biological_process
92914,GO:1904987,"Any process that modulates the frequency, rate or extent of endothelial cell activation.",regulation of endothelial cell activation,biological_process
92915,GO:1904988,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.",negative regulation of endothelial cell activation,biological_process
92916,GO:1904989,"Any process that activates or increases the frequency, rate or extent of endothelial cell activation.",positive regulation of endothelial cell activation,biological_process
92917,GO:1904990,"Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.",regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway,biological_process
92918,GO:1904991,"Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.",negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway,biological_process
92919,GO:1904992,"Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.",positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway,biological_process
92920,GO:1904994,"Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.",regulation of leukocyte adhesion to vascular endothelial cell,biological_process
92921,GO:1904995,"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.",negative regulation of leukocyte adhesion to vascular endothelial cell,biological_process
92922,GO:1904996,"Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.",positive regulation of leukocyte adhesion to vascular endothelial cell,biological_process
92923,GO:1904997,"Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.",regulation of leukocyte adhesion to arterial endothelial cell,biological_process
92924,GO:1904998,"Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.",negative regulation of leukocyte adhesion to arterial endothelial cell,biological_process
92925,GO:1904999,"Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.",positive regulation of leukocyte adhesion to arterial endothelial cell,biological_process
92926,GO:1905000,"Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.",regulation of membrane repolarization during atrial cardiac muscle cell action potential,biological_process
92927,GO:1905001,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.",negative regulation of membrane repolarization during atrial cardiac muscle cell action potential,biological_process
92928,GO:1905002,"Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.",positive regulation of membrane repolarization during atrial cardiac muscle cell action potential,biological_process
92929,GO:1905004,The chemical reactions and pathways resulting in the formation of picolinic acid.,picolinic acid biosynthetic process,biological_process
92930,GO:1905005,"Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.",regulation of epithelial to mesenchymal transition involved in endocardial cushion formation,biological_process
92931,GO:1905006,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.",negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation,biological_process
92932,GO:1905007,"Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.",positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation,biological_process
92933,GO:1905008,"Any process that modulates the frequency, rate or extent of L-lysine import into cell.",regulation of L-lysine import across plasma membrane,biological_process
92934,GO:1905009,"Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.",negative regulation of L-lysine import across plasma membrane,biological_process
92935,GO:1905010,"Any process that activates or increases the frequency, rate or extent of L-lysine import into cell.",positive regulation of L-lysine import across plasma membrane,biological_process
92936,GO:1905011,The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen.,transmembrane phosphate ion transport from cytosol to vacuole,biological_process
92937,GO:1905012,"Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from L-tryptophan.",regulation of 'de novo' NAD biosynthetic process from L-tryptophan,biological_process
92938,GO:1905013,"Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from L-tryptophan.",negative regulation of 'de novo' NAD biosynthetic process from L-tryptophan,biological_process
92939,GO:1905014,"Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from L-tryptophan.",positive regulation of 'de novo' NAD biosynthetic process from L-tryptophan,biological_process
92940,GO:1905024,"Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.",regulation of membrane repolarization during ventricular cardiac muscle cell action potential,biological_process
92941,GO:1905025,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.",negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential,biological_process
92942,GO:1905026,"Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.",positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential,biological_process
92943,GO:1905027,"Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.",regulation of membrane depolarization during AV node cell action potential,biological_process
92944,GO:1905028,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.",negative regulation of membrane depolarization during AV node cell action potential,biological_process
92945,GO:1905029,"Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential.",positive regulation of membrane depolarization during AV node cell action potential,biological_process
92946,GO:1905030,Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.,voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential,molecular_function
92947,GO:1905031,"Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.",regulation of membrane repolarization during cardiac muscle cell action potential,biological_process
92948,GO:1905032,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.",negative regulation of membrane repolarization during cardiac muscle cell action potential,biological_process
92949,GO:1905033,"Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.",positive regulation of membrane repolarization during cardiac muscle cell action potential,biological_process
92950,GO:1905034,"Any process that modulates the frequency, rate or extent of an antifungal innate immune response.",regulation of antifungal innate immune response,biological_process
92951,GO:1905035,"Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.",negative regulation of antifungal innate immune response,biological_process
92952,GO:1905036,"Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.",positive regulation of antifungal innate immune response,biological_process
92953,GO:1905037,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.",autophagosome organization,biological_process
92954,GO:1905039,The process in which carboxylic acid is transported across a membrane.,carboxylic acid transmembrane transport,biological_process
92955,GO:1905040,"The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.",otic placode development,biological_process
92956,GO:1905041,"Any process that modulates the frequency, rate or extent of epithelium regeneration.",regulation of epithelium regeneration,biological_process
92957,GO:1905042,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.",negative regulation of epithelium regeneration,biological_process
92958,GO:1905043,"Any process that activates or increases the frequency, rate or extent of epithelium regeneration.",positive regulation of epithelium regeneration,biological_process
92959,GO:1905047,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.",mitotic spindle pole body organization,biological_process
92960,GO:1905048,"Any process that modulates the frequency, rate or extent of metallopeptidase activity.",regulation of metallopeptidase activity,biological_process
92961,GO:1905049,"Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity.",negative regulation of metallopeptidase activity,biological_process
92962,GO:1905050,"Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.",positive regulation of metallopeptidase activity,biological_process
92963,GO:1905051,"Any process that modulates the frequency, rate or extent of base-excision repair.",regulation of base-excision repair,biological_process
92964,GO:1905052,"Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.",negative regulation of base-excision repair,biological_process
92965,GO:1905053,"Any process that activates or increases the frequency, rate or extent of base-excision repair.",positive regulation of base-excision repair,biological_process
92966,GO:1905056,A calcium-transporting P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration.,P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration,molecular_function
92967,GO:1905059,A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.,P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration,molecular_function
92968,GO:1905060,Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.,calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration,molecular_function
92969,GO:1905061,"Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.",negative regulation of cardioblast proliferation,biological_process
92970,GO:1905062,"Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.",positive regulation of cardioblast proliferation,biological_process
92971,GO:1905063,"Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.",regulation of vascular associated smooth muscle cell differentiation,biological_process
92972,GO:1905064,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.",negative regulation of vascular associated smooth muscle cell differentiation,biological_process
92973,GO:1905065,"Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.",positive regulation of vascular associated smooth muscle cell differentiation,biological_process
92974,GO:1905069,"The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.",allantois development,biological_process
92975,GO:1905070,The orderly movement of an anterior visceral endoderm cell from one site to another.,anterior visceral endoderm cell migration,biological_process
92976,GO:1905071,The disaggregation of an tight junction into its constituent components.,tight junction disassembly,biological_process
92977,GO:1905072,"The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart.",cardiac jelly development,biological_process
92978,GO:1905073,"Any process that modulates the frequency, rate or extent of tight junction disassembly.",regulation of tight junction disassembly,biological_process
92979,GO:1905074,"Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly.",negative regulation of tight junction disassembly,biological_process
92980,GO:1905075,"Any process that activates or increases the frequency, rate or extent of tight junction disassembly.",positive regulation of tight junction disassembly,biological_process
92981,GO:1905079,"Any process that modulates the frequency, rate or extent of cerebellar neuron development.",regulation of cerebellar neuron development,biological_process
92982,GO:1905080,"Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.",negative regulation of cerebellar neuron development,biological_process
92983,GO:1905081,"Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.",positive regulation of cerebellar neuron development,biological_process
92984,GO:1905082,"Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.",regulation of mitochondrial translational elongation,biological_process
92985,GO:1905083,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.",negative regulation of mitochondrial translational elongation,biological_process
92986,GO:1905084,"Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.",positive regulation of mitochondrial translational elongation,biological_process
92987,GO:1905085,"Any process that modulates the frequency, rate or extent of bioluminescence.",regulation of bioluminescence,biological_process
92988,GO:1905086,"Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.",negative regulation of bioluminescence,biological_process
92989,GO:1905087,"Any process that activates or increases the frequency, rate or extent of bioluminescence.",positive regulation of bioluminescence,biological_process
92990,GO:1905088,"Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.",positive regulation of synaptonemal complex assembly,biological_process
92991,GO:1905089,"Any process that modulates the frequency, rate or extent of type 2 mitophagy.",regulation of type 2 mitophagy,biological_process
92992,GO:1905090,"Any process that stops, prevents or reduces the frequency, rate or extent of type 2 mitophagy.",negative regulation of type 2 mitophagy,biological_process
92993,GO:1905091,"Any process that activates or increases the frequency, rate or extent of type 2 mitophagy.",positive regulation of type 2 mitophagy,biological_process
92994,GO:1905092,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.",response to diosgenin,biological_process
92995,GO:1905093,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.",cellular response to diosgenin,biological_process
92996,GO:1905094,"Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.",regulation of apolipoprotein A-I-mediated signaling pathway,biological_process
92997,GO:1905095,"Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.",negative regulation of apolipoprotein A-I-mediated signaling pathway,biological_process
92998,GO:1905096,"Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.",positive regulation of apolipoprotein A-I-mediated signaling pathway,biological_process
92999,GO:1905098,"Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.",negative regulation of guanyl-nucleotide exchange factor activity,biological_process
93000,GO:1905100,"Any process that modulates the frequency, rate or extent of apoptosome assembly.",regulation of apoptosome assembly,biological_process
93001,GO:1905101,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.",negative regulation of apoptosome assembly,biological_process
93002,GO:1905102,"Any process that activates or increases the frequency, rate or extent of apoptosome assembly.",positive regulation of apoptosome assembly,biological_process
93003,GO:1905108,Binding to guanosine.,guanosine binding,molecular_function
93004,GO:1905109,"Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.",regulation of pulmonary blood vessel remodeling,biological_process
93005,GO:1905110,"Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.",negative regulation of pulmonary blood vessel remodeling,biological_process
93006,GO:1905111,"Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.",positive regulation of pulmonary blood vessel remodeling,biological_process
93007,GO:1905115,"Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.",regulation of lateral attachment of mitotic spindle microtubules to kinetochore,biological_process
93008,GO:1905116,"Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.",positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore,biological_process
93009,GO:1905119,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.",response to haloperidol,biological_process
93010,GO:1905120,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.",cellular response to haloperidol,biological_process
93011,GO:1905126,"Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.",regulation of axo-dendritic protein transport,biological_process
93012,GO:1905127,"Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.",negative regulation of axo-dendritic protein transport,biological_process
93013,GO:1905128,"Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.",positive regulation of axo-dendritic protein transport,biological_process
93014,GO:1905130,"The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol.",carcinine import across plasma membrane,biological_process
93015,GO:1905131,Enables the transfer of carcinine from one side of a membrane to the other.,carcinine transmembrane transporter activity,molecular_function
93016,GO:1905132,"Any process that modulates the frequency, rate or extent of meiotic chromosome separation.",regulation of meiotic chromosome separation,biological_process
93017,GO:1905133,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.",negative regulation of meiotic chromosome separation,biological_process
93018,GO:1905134,"Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation.",positive regulation of meiotic chromosome separation,biological_process
93019,GO:1905135,"The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol.",biotin import across plasma membrane,biological_process
93020,GO:1905136,"The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol.",dethiobiotin import across plasma membrane,biological_process
93021,GO:1905137,"Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.",regulation of viral DNA genome packaging via site-specific sequence recognition,biological_process
93022,GO:1905138,"Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.",positive regulation of viral DNA genome packaging via site-specific sequence recognition,biological_process
93023,GO:1905139,The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.,apical ectodermal ridge formation,biological_process
93024,GO:1905140,"Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.",regulation of apical ectodermal ridge formation,biological_process
93025,GO:1905141,"Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.",negative regulation of apical ectodermal ridge formation,biological_process
93026,GO:1905142,"Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.",positive regulation of apical ectodermal ridge formation,biological_process
93027,GO:1905143,"The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.",eukaryotic translation initiation factor 2 complex assembly,biological_process
93028,GO:1905144,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.",response to acetylcholine,biological_process
93029,GO:1905145,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.",cellular response to acetylcholine,biological_process
93030,GO:1905146,Any cellular protein catabolic process that takes place in a lysosome.,lysosomal protein catabolic process,biological_process
93031,GO:1905147,"Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.",regulation of smooth muscle hypertrophy,biological_process
93032,GO:1905148,"Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.",negative regulation of smooth muscle hypertrophy,biological_process
93033,GO:1905149,"Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.",positive regulation of smooth muscle hypertrophy,biological_process
93034,GO:1905150,"Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity.",regulation of voltage-gated sodium channel activity,biological_process
93035,GO:1905152,"Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity.",positive regulation of voltage-gated sodium channel activity,biological_process
93036,GO:1905153,"Any process that modulates the frequency, rate or extent of membrane invagination.",regulation of membrane invagination,biological_process
93037,GO:1905154,"Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.",negative regulation of membrane invagination,biological_process
93038,GO:1905155,"Any process that activates or increases the frequency, rate or extent of membrane invagination.",positive regulation of membrane invagination,biological_process
93039,GO:1905156,"Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.",negative regulation of photosynthesis,biological_process
93040,GO:1905157,"Any process that activates or increases the frequency, rate or extent of photosynthesis.",positive regulation of photosynthesis,biological_process
93041,GO:1905161,"A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.",protein localization to phagocytic vesicle,biological_process
93042,GO:1905162,"Any process that modulates the frequency, rate or extent of phagosome maturation.",regulation of phagosome maturation,biological_process
93043,GO:1905163,"Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.",negative regulation of phagosome maturation,biological_process
93044,GO:1905164,"Any process that activates or increases the frequency, rate or extent of phagosome maturation.",positive regulation of phagosome maturation,biological_process
93045,GO:1905165,"Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.",regulation of lysosomal protein catabolic process,biological_process
93046,GO:1905166,"Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.",negative regulation of lysosomal protein catabolic process,biological_process
93047,GO:1905167,"Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.",positive regulation of lysosomal protein catabolic process,biological_process
93048,GO:1905168,"Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.",positive regulation of double-strand break repair via homologous recombination,biological_process
93049,GO:1905169,"Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.",regulation of protein localization to phagocytic vesicle,biological_process
93050,GO:1905170,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.",negative regulation of protein localization to phagocytic vesicle,biological_process
93051,GO:1905171,"Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.",positive regulation of protein localization to phagocytic vesicle,biological_process
93052,GO:1905172,Binding to a RISC complex.,RISC complex binding,molecular_function
93053,GO:1905173,"The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex.",eukaryotic translation initiation factor 2B complex assembly,biological_process
93054,GO:1905174,"Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.",regulation of vascular associated smooth muscle cell dedifferentiation,biological_process
93055,GO:1905175,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.",negative regulation of vascular associated smooth muscle cell dedifferentiation,biological_process
93056,GO:1905176,"Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.",positive regulation of vascular associated smooth muscle cell dedifferentiation,biological_process
93057,GO:1905177,The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element.,tracheary element differentiation,biological_process
93058,GO:1905178,"Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.",regulation of cardiac muscle tissue regeneration,biological_process
93059,GO:1905179,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.",negative regulation of cardiac muscle tissue regeneration,biological_process
93060,GO:1905180,"Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.",positive regulation of cardiac muscle tissue regeneration,biological_process
93061,GO:1905186,"Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.",regulation of metaphase/anaphase transition of meiosis I,biological_process
93062,GO:1905187,"Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.",negative regulation of metaphase/anaphase transition of meiosis I,biological_process
93063,GO:1905188,"Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.",positive regulation of metaphase/anaphase transition of meiosis I,biological_process
93064,GO:1905189,"Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.",regulation of metaphase/anaphase transition of meiosis II,biological_process
93065,GO:1905190,"Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.",negative regulation of metaphase/anaphase transition of meiosis II,biological_process
93066,GO:1905191,"Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.",positive regulation of metaphase/anaphase transition of meiosis II,biological_process
93067,GO:1905192,"Any process that modulates the frequency, rate or extent of chloroplast fission.",regulation of chloroplast fission,biological_process
93068,GO:1905193,"Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission.",negative regulation of chloroplast fission,biological_process
93069,GO:1905194,"Any process that activates or increases the frequency, rate or extent of chloroplast fission.",positive regulation of chloroplast fission,biological_process
93070,GO:1905198,"The aggregation, arrangement and bonding together of a set of components to form a manchette.",manchette assembly,biological_process
93071,GO:1905199,The disaggregation of a manchette into its constituent components.,manchette disassembly,biological_process
93072,GO:1905200,The directed movement of gibberellic acid across a membrane.,gibberellic acid transmembrane transport,biological_process
93073,GO:1905201,Enables the transfer of gibberellin from one side of a membrane to the other.,gibberellin transmembrane transporter activity,molecular_function
93074,GO:1905202,"A protein complex capable of methylcrotonoyl-CoA carboxylase activity. In mammals, it is a mitochondrial complex comprising a dodecamer of 6 alpha and 6 beta subunits: MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation; MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.",methylcrotonoyl-CoA carboxylase complex,cellular_component
93075,GO:1905203,"Any process that modulates the frequency, rate or extent of connective tissue replacement.",regulation of connective tissue replacement,biological_process
93076,GO:1905204,"Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement.",negative regulation of connective tissue replacement,biological_process
93077,GO:1905205,"Any process that activates or increases the frequency, rate or extent of connective tissue replacement.",positive regulation of connective tissue replacement,biological_process
93078,GO:1905207,"Any process that modulates the frequency, rate or extent of cardiocyte differentiation.",regulation of cardiocyte differentiation,biological_process
93079,GO:1905208,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.",negative regulation of cardiocyte differentiation,biological_process
93080,GO:1905209,"Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.",positive regulation of cardiocyte differentiation,biological_process
93081,GO:1905210,"Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.",regulation of fibroblast chemotaxis,biological_process
93082,GO:1905211,"Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.",negative regulation of fibroblast chemotaxis,biological_process
93083,GO:1905212,"Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.",positive regulation of fibroblast chemotaxis,biological_process
93084,GO:1905213,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.",negative regulation of mitotic chromosome condensation,biological_process
93085,GO:1905216,"Any process that activates or increases the frequency, rate or extent of RNA binding.",positive regulation of RNA binding,biological_process
93086,GO:1905217,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.",response to astaxanthin,biological_process
93087,GO:1905218,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.",cellular response to astaxanthin,biological_process
93088,GO:1905219,"Any process that modulates the frequency, rate or extent of platelet formation.",regulation of platelet formation,biological_process
93089,GO:1905220,"Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.",negative regulation of platelet formation,biological_process
93090,GO:1905221,"Any process that activates or increases the frequency, rate or extent of platelet formation.",positive regulation of platelet formation,biological_process
93091,GO:1905222,The developmental process by which an atrioventricular canal is generated and organized.,atrioventricular canal morphogenesis,biological_process
93092,GO:1905223,The developmental process by which an epicardium is generated and organized.,epicardium morphogenesis,biological_process
93093,GO:1905225,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.",response to thyrotropin-releasing hormone,biological_process
93094,GO:1905229,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.",cellular response to thyrotropin-releasing hormone,biological_process
93095,GO:1905230,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.",response to borneol,biological_process
93096,GO:1905231,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.",cellular response to borneol,biological_process
93097,GO:1905232,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.",cellular response to L-glutamate,biological_process
93098,GO:1905233,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.",response to codeine,biological_process
93099,GO:1905234,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.",cellular response to codeine,biological_process
93100,GO:1905235,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.",response to quercetin,biological_process
93101,GO:1905236,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.",cellular response to quercetin,biological_process
93102,GO:1905237,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.",response to cyclosporin A,biological_process
93103,GO:1905238,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.",cellular response to cyclosporin A,biological_process
93104,GO:1905242,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.","response to 3,3',5-triiodo-L-thyronine",biological_process
93105,GO:1905243,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.","cellular response to 3,3',5-triiodo-L-thyronine",biological_process
93106,GO:1905244,"Any process that modulates the frequency, rate or extent of modification of synaptic structure.",regulation of modification of synaptic structure,biological_process
93107,GO:1905247,"Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity.",positive regulation of aspartic-type peptidase activity,biological_process
93108,GO:1905258,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.",regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway,biological_process
93109,GO:1905259,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.",negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway,biological_process
93110,GO:1905260,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.",positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway,biological_process
93111,GO:1905261,"Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.",regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination,biological_process
93112,GO:1905262,"Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.",negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination,biological_process
93113,GO:1905263,"Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.",positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination,biological_process
93114,GO:1905265,The chemical reactions and pathways resulting in the breakdown of blasticidin S.,blasticidin S catabolic process,biological_process
93115,GO:1905266,The chemical reactions and pathways resulting in the formation of blasticidin S.,blasticidin S biosynthetic process,biological_process
93116,GO:1905268,"Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.",negative regulation of chromatin organization,biological_process
93117,GO:1905269,"Any process that activates or increases the frequency, rate or extent of chromatin organization.",positive regulation of chromatin organization,biological_process
93118,GO:1905270,The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.,Meynert cell differentiation,biological_process
93119,GO:1905273,"Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.","positive regulation of proton-transporting ATP synthase activity, rotational mechanism",biological_process
93120,GO:1905274,"Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.",regulation of modification of postsynaptic actin cytoskeleton,biological_process
93121,GO:1905275,The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.,Rohon-Beard neuron differentiation,biological_process
93122,GO:1905276,"Any process that modulates the frequency, rate or extent of epithelial tube formation.",regulation of epithelial tube formation,biological_process
93123,GO:1905277,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.",negative regulation of epithelial tube formation,biological_process
93124,GO:1905278,"Any process that activates or increases the frequency, rate or extent of epithelial tube formation.",positive regulation of epithelial tube formation,biological_process
93125,GO:1905279,"Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.","regulation of retrograde transport, endosome to Golgi",biological_process
93126,GO:1905280,"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.","negative regulation of retrograde transport, endosome to Golgi",biological_process
93127,GO:1905281,"Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.","positive regulation of retrograde transport, endosome to Golgi",biological_process
93128,GO:1905285,The developmental process by which a fibrous ring of heart is generated and organized.,fibrous ring of heart morphogenesis,biological_process
93129,GO:1905286,A protein complex which is capable of serine-type peptidase activity.,serine-type peptidase complex,cellular_component
93130,GO:1905287,Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.,positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation,biological_process
93131,GO:1905288,Any apoptotic process in a vascular associated smooth muscle cell.,vascular associated smooth muscle cell apoptotic process,biological_process
93132,GO:1905289,"Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade.",regulation of CAMKK-AMPK signaling cascade,biological_process
93133,GO:1905290,"Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade.",negative regulation of CAMKK-AMPK signaling cascade,biological_process
93134,GO:1905291,"Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.",positive regulation of CAMKK-AMPK signaling cascade,biological_process
93135,GO:1905292,"Any process that modulates the frequency, rate or extent of neural crest cell differentiation.",regulation of neural crest cell differentiation,biological_process
93136,GO:1905293,"Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.",negative regulation of neural crest cell differentiation,biological_process
93137,GO:1905294,"Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.",positive regulation of neural crest cell differentiation,biological_process
93138,GO:1905295,"Any process that modulates the frequency, rate or extent of neural crest cell fate specification.",regulation of neural crest cell fate specification,biological_process
93139,GO:1905296,"Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.",negative regulation of neural crest cell fate specification,biological_process
93140,GO:1905297,"Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification.",positive regulation of neural crest cell fate specification,biological_process
93141,GO:1905298,"Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.",regulation of intestinal epithelial cell development,biological_process
93142,GO:1905299,"Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.",negative regulation of intestinal epithelial cell development,biological_process
93143,GO:1905300,"Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.",positive regulation of intestinal epithelial cell development,biological_process
93144,GO:1905301,"Any process that modulates the frequency, rate or extent of macropinocytosis.",regulation of macropinocytosis,biological_process
93145,GO:1905302,"Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.",negative regulation of macropinocytosis,biological_process
93146,GO:1905303,"Any process that activates or increases the frequency, rate or extent of macropinocytosis.",positive regulation of macropinocytosis,biological_process
93147,GO:1905304,"Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.",regulation of cardiac myofibril assembly,biological_process
93148,GO:1905305,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.",negative regulation of cardiac myofibril assembly,biological_process
93149,GO:1905306,"Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.",positive regulation of cardiac myofibril assembly,biological_process
93150,GO:1905307,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.",response to miconazole,biological_process
93151,GO:1905308,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.",cellular response to miconazole,biological_process
93152,GO:1905310,"Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.",regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis,biological_process
93153,GO:1905312,"Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.",positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis,biological_process
93154,GO:1905314,"The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.",semi-lunar valve development,biological_process
93155,GO:1905315,Any cell proliferation that is involved in endocardial cushion morphogenesis.,cell proliferation involved in endocardial cushion morphogenesis,biological_process
93156,GO:1905316,The developmental process by which a superior endocardial cushion is generated and organized.,superior endocardial cushion morphogenesis,biological_process
93157,GO:1905317,The developmental process by which an inferior endocardial cushion is generated and organized.,inferior endocardial cushion morphogenesis,biological_process
93158,GO:1905318,Any spindle assembly checkpoint that is involved in meiosis I.,meiosis I spindle assembly checkpoint signaling,biological_process
93159,GO:1905319,The orderly movement of a mesenchymal stem cell from one site to another.,mesenchymal stem cell migration,biological_process
93160,GO:1905320,"Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.",regulation of mesenchymal stem cell migration,biological_process
93161,GO:1905321,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.",negative regulation of mesenchymal stem cell migration,biological_process
93162,GO:1905322,"Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.",positive regulation of mesenchymal stem cell migration,biological_process
93163,GO:1905323,"The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.",telomerase holoenzyme complex assembly,biological_process
93164,GO:1905324,"The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex.",telomere-telomerase complex assembly,biological_process
93165,GO:1905325,"Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.",regulation of meiosis I spindle assembly checkpoint,biological_process
93166,GO:1905326,"Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.",positive regulation of meiosis I spindle assembly checkpoint,biological_process
93167,GO:1905327,The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.,tracheoesophageal septum formation,biological_process
93168,GO:1905328,"The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure.",plant septum development,biological_process
93169,GO:1905329,"The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-c...",sphingoid long-chain base transport,biological_process
93170,GO:1905330,"Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.",regulation of morphogenesis of an epithelium,biological_process
93171,GO:1905331,"Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.",negative regulation of morphogenesis of an epithelium,biological_process
93172,GO:1905332,"Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.",positive regulation of morphogenesis of an epithelium,biological_process
93173,GO:1905333,"Any process that modulates the frequency, rate or extent of gastric motility.",regulation of gastric motility,biological_process
93174,GO:1905334,Binding to a Swi5-Sfr1 complex.,Swi5-Sfr1 complex binding,molecular_function
93175,GO:1905335,"Any process that modulates the frequency, rate or extent of aggrephagy.",regulation of aggrephagy,biological_process
93176,GO:1905336,"Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.",negative regulation of aggrephagy,biological_process
93177,GO:1905337,"Any process that activates or increases the frequency, rate or extent of aggrephagy.",positive regulation of aggrephagy,biological_process
93178,GO:1905340,"Any process that modulates the frequency, rate or extent of protein localization to kinetochore.",regulation of protein localization to kinetochore,biological_process
93179,GO:1905341,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.",negative regulation of protein localization to kinetochore,biological_process
93180,GO:1905342,"Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.",positive regulation of protein localization to kinetochore,biological_process
93181,GO:1905344,The chemical reactions and pathways resulting in the breakdown of prostaglandin.,prostaglandin catabolic process,biological_process
93182,GO:1905345,"A process in which a protein is transported to, or maintained in, a location within a cleavage furrow.",protein localization to cleavage furrow,biological_process
93183,GO:1905346,"A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.",protein localization to cleavage furrow rim,biological_process
93184,GO:1905347,A protein complex which is capable of endodeoxyribonuclease activity.,endodeoxyribonuclease complex,cellular_component
93185,GO:1905348,A protein complex which is capable of endonuclease activity.,endonuclease complex,cellular_component
93186,GO:1905349,"The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.",ciliary transition zone assembly,biological_process
93187,GO:1905350,"The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate.",Y-shaped link assembly,biological_process
93188,GO:1905351,The orderly movement of a pericyte cell from one site to another.,pericyte cell migration,biological_process
93189,GO:1905352,"The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace.",ciliary necklace assembly,biological_process
93190,GO:1905354,A protein complex which is capable of exoribonuclease activity.,exoribonuclease complex,cellular_component
93191,GO:1905355,"The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.",spine apparatus assembly,biological_process
93192,GO:1905356,"Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.",regulation of snRNA pseudouridine synthesis,biological_process
93193,GO:1905357,"Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.",negative regulation of snRNA pseudouridine synthesis,biological_process
93194,GO:1905358,"Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis.",positive regulation of snRNA pseudouridine synthesis,biological_process
93195,GO:1905359,"A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.",protein localization to meiotic spindle,biological_process
93196,GO:1905360,A protein complex which is capable of GTPase activity.,GTPase complex,cellular_component
93197,GO:1905362,"Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.",negative regulation of endosomal vesicle fusion,biological_process
93198,GO:1905363,"Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.",positive regulation of endosomal vesicle fusion,biological_process
93199,GO:1905364,"Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.",regulation of endosomal vesicle fusion,biological_process
93200,GO:1905365,"Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.",regulation of intralumenal vesicle formation,biological_process
93201,GO:1905366,"Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.",negative regulation of intralumenal vesicle formation,biological_process
93202,GO:1905367,"Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation.",positive regulation of intralumenal vesicle formation,biological_process
93203,GO:1905368,A protein complex which is capable of peptidase activity.,peptidase complex,cellular_component
93204,GO:1905369,A protein complex which is capable of endopeptidase activity.,endopeptidase complex,cellular_component
93205,GO:1905370,A protein complex which is capable of serine-type endopeptidase activity.,serine-type endopeptidase complex,cellular_component
93206,GO:1905372,The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.,ceramide phosphoethanolamine catabolic process,biological_process
93207,GO:1905373,The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.,ceramide phosphoethanolamine biosynthetic process,biological_process
93208,GO:1905374,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.",response to homocysteine,biological_process
93209,GO:1905375,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.",cellular response to homocysteine,biological_process
93210,GO:1905377,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.",response to D-galactose,biological_process
93211,GO:1905378,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.",cellular response to D-galactose,biological_process
93212,GO:1905379,A protein complex which is capable of beta-N-acetylhexosaminidase activity.,beta-N-acetylhexosaminidase complex,cellular_component
93213,GO:1905380,"Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.",regulation of snRNA transcription by RNA polymerase II,biological_process
93214,GO:1905381,"Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.",negative regulation of snRNA transcription by RNA polymerase II,biological_process
93215,GO:1905382,"Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.",positive regulation of snRNA transcription by RNA polymerase II,biological_process
93216,GO:1905383,"A process in which a protein is transported to, or maintained in, a location within a presynapse.",protein localization to presynapse,biological_process
93217,GO:1905384,"Any process that modulates the frequency, rate or extent of protein localization to presynapse.",regulation of protein localization to presynapse,biological_process
93218,GO:1905385,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.",negative regulation of protein localization to presynapse,biological_process
93219,GO:1905386,"Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.",positive regulation of protein localization to presynapse,biological_process
93220,GO:1905387,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.",response to beta-carotene,biological_process
93221,GO:1905388,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.",cellular response to beta-carotene,biological_process
93222,GO:1905389,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.",response to leukotriene B4,biological_process
93223,GO:1905390,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.",cellular response to leukotriene B4,biological_process
93224,GO:1905391,Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis.,regulation of protein localization to cell division site involved in cell separation after cytokinesis,biological_process
93225,GO:1905392,The developmental process by which a plant organ is generated and organized.,plant organ morphogenesis,biological_process
93226,GO:1905393,The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.,plant organ formation,biological_process
93227,GO:1905394,Binding to a retromer complex.,retromer complex binding,molecular_function
93228,GO:1905395,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.",response to flavonoid,biological_process
93229,GO:1905396,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.",cellular response to flavonoid,biological_process
93230,GO:1905397,"Any apoptotic process in an activated CD8-positive, alpha-beta T cell.","activated CD8-positive, alpha-beta T cell apoptotic process",biological_process
93231,GO:1905398,"Any apoptotic process in an activated CD4-positive, alpha-beta T cell.","activated CD4-positive, alpha-beta T cell apoptotic process",biological_process
93232,GO:1905399,"Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.","regulation of activated CD4-positive, alpha-beta T cell apoptotic process",biological_process
93233,GO:1905400,"Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.","negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process",biological_process
93234,GO:1905401,"Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.","positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process",biological_process
93235,GO:1905402,"Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.","regulation of activated CD8-positive, alpha-beta T cell apoptotic process",biological_process
93236,GO:1905403,"Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.","negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process",biological_process
93237,GO:1905404,"Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.","positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process",biological_process
93238,GO:1905413,"Any process that modulates the frequency, rate or extent of dense core granule exocytosis.",regulation of dense core granule exocytosis,biological_process
93239,GO:1905414,"Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.",negative regulation of dense core granule exocytosis,biological_process
93240,GO:1905415,"Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.",positive regulation of dense core granule exocytosis,biological_process
93241,GO:1905416,"Any process that modulates the frequency, rate or extent of amoeboid sperm motility.",regulation of amoeboid sperm motility,biological_process
93242,GO:1905417,"Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.",negative regulation of amoeboid sperm motility,biological_process
93243,GO:1905418,"Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.",positive regulation of amoeboid sperm motility,biological_process
93244,GO:1905421,"Any process that modulates the frequency, rate or extent of plant organ morphogenesis.",regulation of plant organ morphogenesis,biological_process
93245,GO:1905422,"Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.",negative regulation of plant organ morphogenesis,biological_process
93246,GO:1905423,"Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.",positive regulation of plant organ morphogenesis,biological_process
93247,GO:1905428,"Any process that modulates the frequency, rate or extent of plant organ formation.",regulation of plant organ formation,biological_process
93248,GO:1905429,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.",response to glycine,biological_process
93249,GO:1905430,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.",cellular response to glycine,biological_process
93250,GO:1905431,"The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",microcystin transport,biological_process
93251,GO:1905432,"Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.",regulation of retrograde trans-synaptic signaling by neuropeptide,biological_process
93252,GO:1905433,"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.",negative regulation of retrograde trans-synaptic signaling by neuropeptide,biological_process
93253,GO:1905434,"Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.",positive regulation of retrograde trans-synaptic signaling by neuropeptide,biological_process
93254,GO:1905439,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.",response to chondroitin 6'-sulfate,biological_process
93255,GO:1905440,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.",cellular response to chondroitin 6'-sulfate,biological_process
93256,GO:1905441,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.",response to chondroitin 4'-sulfate,biological_process
93257,GO:1905442,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.",cellular response to chondroitin 4'-sulfate,biological_process
93258,GO:1905443,"Any process that modulates the frequency, rate or extent of clathrin coat assembly.",regulation of clathrin coat assembly,biological_process
93259,GO:1905444,"Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly.",negative regulation of clathrin coat assembly,biological_process
93260,GO:1905445,"Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.",positive regulation of clathrin coat assembly,biological_process
93261,GO:1905446,"Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.",regulation of mitochondrial ATP synthesis coupled electron transport,biological_process
93262,GO:1905447,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.",negative regulation of mitochondrial ATP synthesis coupled electron transport,biological_process
93263,GO:1905448,"Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.",positive regulation of mitochondrial ATP synthesis coupled electron transport,biological_process
93264,GO:1905450,"Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.",negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis,biological_process
93265,GO:1905451,"Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.",positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis,biological_process
93266,GO:1905453,"Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.",regulation of myeloid progenitor cell differentiation,biological_process
93267,GO:1905454,"Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.",negative regulation of myeloid progenitor cell differentiation,biological_process
93268,GO:1905455,"Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.",positive regulation of myeloid progenitor cell differentiation,biological_process
93269,GO:1905456,"Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.",regulation of lymphoid progenitor cell differentiation,biological_process
93270,GO:1905457,"Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.",negative regulation of lymphoid progenitor cell differentiation,biological_process
93271,GO:1905458,"Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.",positive regulation of lymphoid progenitor cell differentiation,biological_process
93272,GO:1905459,"Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.",regulation of vascular associated smooth muscle cell apoptotic process,biological_process
93273,GO:1905460,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.",negative regulation of vascular associated smooth muscle cell apoptotic process,biological_process
93274,GO:1905461,"Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.",positive regulation of vascular associated smooth muscle cell apoptotic process,biological_process
93275,GO:1905475,"Any process that modulates the frequency, rate or extent of protein localization to membrane.",regulation of protein localization to membrane,biological_process
93276,GO:1905476,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.",negative regulation of protein localization to membrane,biological_process
93277,GO:1905477,"Any process that activates or increases the frequency, rate or extent of protein localization to membrane.",positive regulation of protein localization to membrane,biological_process
93278,GO:1905483,"Any process that modulates the frequency, rate or extent of motor neuron migration.",regulation of motor neuron migration,biological_process
93279,GO:1905484,"Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.",negative regulation of motor neuron migration,biological_process
93280,GO:1905485,"Any process that activates or increases the frequency, rate or extent of motor neuron migration.",positive regulation of motor neuron migration,biological_process
93281,GO:1905486,"Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.",regulation of anterior/posterior axon guidance,biological_process
93282,GO:1905487,"Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance.",negative regulation of anterior/posterior axon guidance,biological_process
93283,GO:1905488,"Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.",positive regulation of anterior/posterior axon guidance,biological_process
93284,GO:1905489,"Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.",regulation of sensory neuron axon guidance,biological_process
93285,GO:1905490,"Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.",negative regulation of sensory neuron axon guidance,biological_process
93286,GO:1905491,"Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.",positive regulation of sensory neuron axon guidance,biological_process
93287,GO:1905492,"Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.",positive regulation of branching morphogenesis of a nerve,biological_process
93288,GO:1905499,"The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.",trichome papilla formation,biological_process
93289,GO:1905502,"Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.",acetyl-CoA binding,molecular_function
93290,GO:1905503,"Any process that modulates the frequency, rate or extent of motile cilium assembly.",regulation of motile cilium assembly,biological_process
93291,GO:1905504,"Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.",negative regulation of motile cilium assembly,biological_process
93292,GO:1905505,"Any process that activates or increases the frequency, rate or extent of motile cilium assembly.",positive regulation of motile cilium assembly,biological_process
93293,GO:1905506,Any plastid stroma that is part of a gerontoplast.,gerontoplast stroma,cellular_component
93294,GO:1905508,"A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.",protein localization to microtubule organizing center,biological_process
93295,GO:1905509,"A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.",protein localization to interphase microtubule organizing center,biological_process
93296,GO:1905510,"Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.",negative regulation of myosin II filament assembly,biological_process
93297,GO:1905511,"Any process that activates or increases the frequency, rate or extent of myosin II filament assembly.",positive regulation of myosin II filament assembly,biological_process
93298,GO:1905512,"Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.",regulation of short-term synaptic potentiation,biological_process
93299,GO:1905513,"Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.",negative regulation of short-term synaptic potentiation,biological_process
93300,GO:1905514,"Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.",positive regulation of short-term synaptic potentiation,biological_process
93301,GO:1905515,"The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.",non-motile cilium assembly,biological_process
93302,GO:1905516,"Any process that activates or increases the frequency, rate or extent of fertilization.",positive regulation of fertilization,biological_process
93303,GO:1905517,The orderly movement of a macrophage from one site to another.,macrophage migration,biological_process
93304,GO:1905518,"Any process that modulates the frequency, rate or extent of presynaptic active zone assembly.",regulation of presynaptic active zone assembly,biological_process
93305,GO:1905519,"Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.",negative regulation of presynaptic active zone assembly,biological_process
93306,GO:1905520,"Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.",positive regulation of presynaptic active zone assembly,biological_process
93307,GO:1905521,"Any process that modulates the frequency, rate or extent of macrophage migration.",regulation of macrophage migration,biological_process
93308,GO:1905522,"Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.",negative regulation of macrophage migration,biological_process
93309,GO:1905523,"Any process that activates or increases the frequency, rate or extent of macrophage migration.",positive regulation of macrophage migration,biological_process
93310,GO:1905524,"Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination.",negative regulation of protein autoubiquitination,biological_process
93311,GO:1905529,"Any process that modulates the frequency, rate or extent of uracil import across plasma membrane.",regulation of uracil import across plasma membrane,biological_process
93312,GO:1905530,"Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.",negative regulation of uracil import across plasma membrane,biological_process
93313,GO:1905531,"Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.",positive regulation of uracil import across plasma membrane,biological_process
93314,GO:1905532,"Any process that modulates the frequency, rate or extent of L-leucine import across plasma membrane.",regulation of L-leucine import across plasma membrane,biological_process
93315,GO:1905533,"Any process that stops, prevents or reduces the frequency, rate or extent of L-leucine import across plasma membrane.",negative regulation of L-leucine import across plasma membrane,biological_process
93316,GO:1905534,"Any process that activates or increases the frequency, rate or extent of L-leucine import across plasma membrane.",positive regulation of L-leucine import across plasma membrane,biological_process
93317,GO:1905535,"Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.",regulation of eukaryotic translation initiation factor 4F complex assembly,biological_process
93318,GO:1905536,"Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.",negative regulation of eukaryotic translation initiation factor 4F complex assembly,biological_process
93319,GO:1905537,"Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.",positive regulation of eukaryotic translation initiation factor 4F complex assembly,biological_process
93320,GO:1905539,"Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway.",regulation of postsynapse to nucleus signaling pathway,biological_process
93321,GO:1905540,"A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.",interleukin-7 receptor complex,cellular_component
93322,GO:1905541,"Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.",regulation of L-arginine import across plasma membrane,biological_process
93323,GO:1905542,"Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane.",negative regulation of L-arginine import across plasma membrane,biological_process
93324,GO:1905543,"A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors.",interleukin-15 receptor complex,cellular_component
93325,GO:1905544,"The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol.",L-methionine import across plasma membrane,biological_process
93326,GO:1905546,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.",cellular response to phenylpropanoid,biological_process
93327,GO:1905550,"Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.",regulation of protein localization to endoplasmic reticulum,biological_process
93328,GO:1905551,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.",negative regulation of protein localization to endoplasmic reticulum,biological_process
93329,GO:1905552,"Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.",positive regulation of protein localization to endoplasmic reticulum,biological_process
93330,GO:1905553,"Any process that modulates the frequency, rate or extent of blood vessel branching.",regulation of blood vessel branching,biological_process
93331,GO:1905554,"Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.",negative regulation of blood vessel branching,biological_process
93332,GO:1905555,"Any process that activates or increases the frequency, rate or extent of blood vessel branching.",positive regulation of blood vessel branching,biological_process
93333,GO:1905556,"The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.",ciliary vesicle assembly,biological_process
93334,GO:1905557,"Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.",regulation of mitotic nuclear envelope disassembly,biological_process
93335,GO:1905558,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.",negative regulation of mitotic nuclear envelope disassembly,biological_process
93336,GO:1905559,"Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.",positive regulation of mitotic nuclear envelope disassembly,biological_process
93337,GO:1905560,"Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly.",negative regulation of kinetochore assembly,biological_process
93338,GO:1905561,"Any process that activates or increases the frequency, rate or extent of kinetochore assembly.",positive regulation of kinetochore assembly,biological_process
93339,GO:1905562,"Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.",regulation of vascular endothelial cell proliferation,biological_process
93340,GO:1905563,"Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.",negative regulation of vascular endothelial cell proliferation,biological_process
93341,GO:1905564,"Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.",positive regulation of vascular endothelial cell proliferation,biological_process
93342,GO:1905568,"Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process.",regulation of ferrichrome biosynthetic process,biological_process
93343,GO:1905569,"Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process.",negative regulation of ferrichrome biosynthetic process,biological_process
93344,GO:1905570,"Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process.",positive regulation of ferrichrome biosynthetic process,biological_process
93345,GO:1905571,"A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.",interleukin-10 receptor complex,cellular_component
93346,GO:1905572,The directed movement of ganglioside GM1 to membrane.,ganglioside GM1 transport to membrane,biological_process
93347,GO:1905573,Binding to ganglioside GM1.,ganglioside GM1 binding,molecular_function
93348,GO:1905574,Binding to ganglioside GM2.,ganglioside GM2 binding,molecular_function
93349,GO:1905575,Binding to ganglioside GM3.,ganglioside GM3 binding,molecular_function
93350,GO:1905576,Binding to ganglioside GT1b.,ganglioside GT1b binding,molecular_function
93351,GO:1905577,Binding to ganglioside GP1c.,ganglioside GP1c binding,molecular_function
93352,GO:1905578,"Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.",regulation of ERBB3 signaling pathway,biological_process
93353,GO:1905579,"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.",negative regulation of ERBB3 signaling pathway,biological_process
93354,GO:1905580,"Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.",positive regulation of ERBB3 signaling pathway,biological_process
93355,GO:1905581,"Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.",positive regulation of low-density lipoprotein particle clearance,biological_process
93356,GO:1905582,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.",response to mannose,biological_process
93357,GO:1905583,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.",cellular response to mannose,biological_process
93358,GO:1905584,Any apoptotic process in an outer hair cell.,outer hair cell apoptotic process,biological_process
93359,GO:1905585,"Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process.",regulation of outer hair cell apoptotic process,biological_process
93360,GO:1905586,"Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.",negative regulation of outer hair cell apoptotic process,biological_process
93361,GO:1905587,"Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.",positive regulation of outer hair cell apoptotic process,biological_process
93362,GO:1905589,"Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.",positive regulation of L-arginine import across plasma membrane,biological_process
93363,GO:1905590,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.",fibronectin fibril organization,biological_process
93364,GO:1905591,"Any process that modulates the frequency, rate or extent of optical nerve axon regeneration.",regulation of optical nerve axon regeneration,biological_process
93365,GO:1905592,"Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration.",negative regulation of optical nerve axon regeneration,biological_process
93366,GO:1905593,"Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration.",positive regulation of optical nerve axon regeneration,biological_process
93367,GO:1905601,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.",negative regulation of receptor-mediated endocytosis involved in cholesterol transport,biological_process
93368,GO:1905602,"Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.",positive regulation of receptor-mediated endocytosis involved in cholesterol transport,biological_process
93369,GO:1905603,"Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.",regulation of blood-brain barrier permeability,biological_process
93370,GO:1905604,"Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.",negative regulation of blood-brain barrier permeability,biological_process
93371,GO:1905605,"Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.",positive regulation of blood-brain barrier permeability,biological_process
93372,GO:1905606,"Any process that modulates the frequency, rate or extent of presynapse assembly.",regulation of presynapse assembly,biological_process
93373,GO:1905607,"Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.",negative regulation of presynapse assembly,biological_process
93374,GO:1905608,"Any process that activates or increases the frequency, rate or extent of presynapse assembly.",positive regulation of presynapse assembly,biological_process
93375,GO:1905609,"Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.",positive regulation of smooth muscle cell-matrix adhesion,biological_process
93376,GO:1905613,"Any process that modulates the frequency, rate or extent of developmental vegetative growth.",regulation of developmental vegetative growth,biological_process
93377,GO:1905614,"Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.",negative regulation of developmental vegetative growth,biological_process
93378,GO:1905615,"Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.",positive regulation of developmental vegetative growth,biological_process
93379,GO:1905622,"Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.",negative regulation of leaf development,biological_process
93380,GO:1905623,"Any process that activates or increases the frequency, rate or extent of leaf development.",positive regulation of leaf development,biological_process
93381,GO:1905624,"Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane.",regulation of L-methionine import across plasma membrane,biological_process
93382,GO:1905625,"Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane.",negative regulation of L-methionine import across plasma membrane,biological_process
93383,GO:1905626,"Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.",positive regulation of L-methionine import across plasma membrane,biological_process
93384,GO:1905627,"Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.",regulation of serotonin biosynthetic process,biological_process
93385,GO:1905628,"Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.",negative regulation of serotonin biosynthetic process,biological_process
93386,GO:1905629,"Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.",positive regulation of serotonin biosynthetic process,biological_process
93387,GO:1905630,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.",response to glyceraldehyde,biological_process
93388,GO:1905631,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.",cellular response to glyceraldehyde,biological_process
93389,GO:1905632,"A process in which a protein is transported to, or maintained in, a location within an euchromatin.",protein localization to euchromatin,biological_process
93390,GO:1905633,The directed movement of a protein to a specific location in an euchromatin.,establishment of protein localization to euchromatin,biological_process
93391,GO:1905634,"Any process that modulates the frequency, rate or extent of protein localization to chromatin.",regulation of protein localization to chromatin,biological_process
93392,GO:1905635,"The aggregation, arrangement and bonding together of a set of components to form a FACT complex.",FACT complex assembly,biological_process
93393,GO:1905637,"Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.",regulation of mitochondrial mRNA catabolic process,biological_process
93394,GO:1905638,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.",negative regulation of mitochondrial mRNA catabolic process,biological_process
93395,GO:1905639,"Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.",positive regulation of mitochondrial mRNA catabolic process,biological_process
93396,GO:1905640,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.",response to acetaldehyde,biological_process
93397,GO:1905641,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.",cellular response to acetaldehyde,biological_process
93398,GO:1905644,"Any process that modulates the frequency, rate or extent of FACT complex assembly.",regulation of FACT complex assembly,biological_process
93399,GO:1905645,"Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly.",negative regulation of FACT complex assembly,biological_process
93400,GO:1905646,"Any process that activates or increases the frequency, rate or extent of FACT complex assembly.",positive regulation of FACT complex assembly,biological_process
93401,GO:1905647,The directed movement of proline from outside of a cell into the cytoplasmic compartment.,proline import across plasma membrane,biological_process
93402,GO:1905648,"Any process that modulates the frequency, rate or extent of shell calcification.",regulation of shell calcification,biological_process
93403,GO:1905649,"Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.",negative regulation of shell calcification,biological_process
93404,GO:1905650,"Any process that activates or increases the frequency, rate or extent of shell calcification.",positive regulation of shell calcification,biological_process
93405,GO:1905651,"Any process that modulates the frequency, rate or extent of artery morphogenesis.",regulation of artery morphogenesis,biological_process
93406,GO:1905652,"Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.",negative regulation of artery morphogenesis,biological_process
93407,GO:1905653,"Any process that activates or increases the frequency, rate or extent of artery morphogenesis.",positive regulation of artery morphogenesis,biological_process
93408,GO:1905654,"Any process that modulates the frequency, rate or extent of artery smooth muscle contraction.",regulation of artery smooth muscle contraction,biological_process
93409,GO:1905655,"Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.",negative regulation of artery smooth muscle contraction,biological_process
93410,GO:1905656,"Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction.",positive regulation of artery smooth muscle contraction,biological_process
93411,GO:1905660,"The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.",mitotic checkpoint complex assembly,biological_process
93412,GO:1905664,"Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.",regulation of calcium ion import across plasma membrane,biological_process
93413,GO:1905665,"Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.",positive regulation of calcium ion import across plasma membrane,biological_process
93414,GO:1905666,"Any process that modulates the frequency, rate or extent of protein localization to endosome.",regulation of protein localization to endosome,biological_process
93415,GO:1905667,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.",negative regulation of protein localization to endosome,biological_process
93416,GO:1905668,"Any process that activates or increases the frequency, rate or extent of protein localization to endosome.",positive regulation of protein localization to endosome,biological_process
93417,GO:1905669,"The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.",TORC1 complex assembly,biological_process
93418,GO:1905670,The disaggregation of a TORC2 complex into its constituent components.,TORC2 complex disassembly,biological_process
93419,GO:1905671,"Any process that modulates the frequency, rate or extent of lysosome organization.",regulation of lysosome organization,biological_process
93420,GO:1905672,"Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.",negative regulation of lysosome organization,biological_process
93421,GO:1905673,"Any process that activates or increases the frequency, rate or extent of lysosome organization.",positive regulation of lysosome organization,biological_process
93422,GO:1905674,"Any process that modulates the frequency, rate or extent of adaptive immune memory response.",regulation of adaptive immune memory response,biological_process
93423,GO:1905675,"Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.",negative regulation of adaptive immune memory response,biological_process
93424,GO:1905676,"Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.",positive regulation of adaptive immune memory response,biological_process
93425,GO:1905677,"Any process that modulates the frequency, rate or extent of adaptive immune effector response.",regulation of adaptive immune effector response,biological_process
93426,GO:1905678,"Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.",negative regulation of adaptive immune effector response,biological_process
93427,GO:1905679,"Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.",positive regulation of adaptive immune effector response,biological_process
93428,GO:1905680,"Any process that modulates the frequency, rate or extent of innate immunity memory response.",regulation of innate immunity memory response,biological_process
93429,GO:1905681,"Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.",negative regulation of innate immunity memory response,biological_process
93430,GO:1905682,"Any process that activates or increases the frequency, rate or extent of innate immunity memory response.",positive regulation of innate immunity memory response,biological_process
93431,GO:1905684,"Any process that modulates the frequency, rate or extent of plasma membrane repair.",regulation of plasma membrane repair,biological_process
93432,GO:1905685,"Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.",negative regulation of plasma membrane repair,biological_process
93433,GO:1905686,"Any process that activates or increases the frequency, rate or extent of plasma membrane repair.",positive regulation of plasma membrane repair,biological_process
93434,GO:1905690,The disaggregation of a nucleus into its constituent components.,nucleus disassembly,biological_process
93435,GO:1905691,The disaggregation of a lipid particle into its constituent components.,lipid droplet disassembly,biological_process
93436,GO:1905692,The disaggregation of an endoplasmic reticulum into its constituent components.,endoplasmic reticulum disassembly,biological_process
93437,GO:1905693,"Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.",regulation of phosphatidic acid biosynthetic process,biological_process
93438,GO:1905694,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.",negative regulation of phosphatidic acid biosynthetic process,biological_process
93439,GO:1905695,"Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.",positive regulation of phosphatidic acid biosynthetic process,biological_process
93440,GO:1905699,"Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",regulation of xenobiotic detoxification by transmembrane export across the plasma membrane,biological_process
93441,GO:1905700,"Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane,biological_process
93442,GO:1905701,"Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.",positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane,biological_process
93443,GO:1905702,"Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.",regulation of inhibitory synapse assembly,biological_process
93444,GO:1905703,"Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.",negative regulation of inhibitory synapse assembly,biological_process
93445,GO:1905704,"Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly.",positive regulation of inhibitory synapse assembly,biological_process
93446,GO:1905706,"Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.",regulation of mitochondrial ATP synthesis coupled proton transport,biological_process
93447,GO:1905707,"Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.",negative regulation of mitochondrial ATP synthesis coupled proton transport,biological_process
93448,GO:1905709,"Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.",negative regulation of membrane permeability,biological_process
93449,GO:1905710,"Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.",positive regulation of membrane permeability,biological_process
93450,GO:1905711,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.",response to phosphatidylethanolamine,biological_process
93451,GO:1905712,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.",cellular response to phosphatidylethanolamine,biological_process
93452,GO:1905715,"Any process that modulates the frequency, rate or extent of cornification.",regulation of cornification,biological_process
93453,GO:1905716,"Any process that stops, prevents or reduces the frequency, rate or extent of cornification.",negative regulation of cornification,biological_process
93454,GO:1905717,"Any process that activates or increases the frequency, rate or extent of cornification.",positive regulation of cornification,biological_process
93455,GO:1905719,"A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.",protein localization to perinuclear region of cytoplasm,biological_process
93456,GO:1905720,Any microtubule bundle that is part of a cytoplasm.,cytoplasmic microtubule bundle,cellular_component
93457,GO:1905721,Any microtubule end that is part of a mitotic spindle astral microtubule.,mitotic spindle astral microtubule end,cellular_component
93458,GO:1905722,"Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process.",regulation of trypanothione biosynthetic process,biological_process
93459,GO:1905723,"Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process.",negative regulation of trypanothione biosynthetic process,biological_process
93460,GO:1905724,"Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process.",positive regulation of trypanothione biosynthetic process,biological_process
93461,GO:1905725,"A process in which a protein is transported to, or maintained in, a location at a microtubule end.",protein localization to microtubule end,biological_process
93462,GO:1905735,"Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane.",regulation of L-proline import across plasma membrane,biological_process
93463,GO:1905736,"Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane.",negative regulation of L-proline import across plasma membrane,biological_process
93464,GO:1905737,"Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.",positive regulation of L-proline import across plasma membrane,biological_process
93465,GO:1905742,A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity.,Ras guanyl-nucleotide exchange factor complex,cellular_component
93466,GO:1905744,"Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.","regulation of mRNA cis splicing, via spliceosome",biological_process
93467,GO:1905745,"Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.","negative regulation of mRNA cis splicing, via spliceosome",biological_process
93468,GO:1905746,"Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.","positive regulation of mRNA cis splicing, via spliceosome",biological_process
93469,GO:1905747,"Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.",negative regulation of saliva secretion,biological_process
93470,GO:1905748,The developmental process by which a hard palate is generated and organized.,hard palate morphogenesis,biological_process
93471,GO:1905749,"Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.",regulation of endosome to plasma membrane protein transport,biological_process
93472,GO:1905750,"Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.",negative regulation of endosome to plasma membrane protein transport,biological_process
93473,GO:1905751,"Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.",positive regulation of endosome to plasma membrane protein transport,biological_process
93474,GO:1905754,Any nucleus that is part of a ascospore-type prospore.,ascospore-type prospore nucleus,cellular_component
93475,GO:1905755,"A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.",protein localization to cytoplasmic microtubule,biological_process
93476,GO:1905756,"Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.",regulation of primary cell septum biogenesis,biological_process
93477,GO:1905757,"Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.",negative regulation of primary cell septum biogenesis,biological_process
93478,GO:1905758,"Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.",positive regulation of primary cell septum biogenesis,biological_process
93479,GO:1905759,Any microtubule that is part of a post-anaphase microtubule array.,post-anaphase array microtubule,cellular_component
93480,GO:1905760,Any microtubule end that is part of a post-anaphase array microtubule.,post-anaphase array microtubule end,cellular_component
93481,GO:1905761,Binding to a SCF ubiquitin ligase complex.,SCF ubiquitin ligase complex binding,molecular_function
93482,GO:1905762,Binding to a CCR4-NOT complex.,CCR4-NOT complex binding,molecular_function
93483,GO:1905763,Binding to a MTREC complex.,MTREC complex binding,molecular_function
93484,GO:1905764,"Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.",regulation of protection from non-homologous end joining at telomere,biological_process
93485,GO:1905765,"Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.",negative regulation of protection from non-homologous end joining at telomere,biological_process
93486,GO:1905766,"Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.",positive regulation of protection from non-homologous end joining at telomere,biological_process
93487,GO:1905770,"Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.",regulation of mesodermal cell differentiation,biological_process
93488,GO:1905771,"Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.",negative regulation of mesodermal cell differentiation,biological_process
93489,GO:1905772,"Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.",positive regulation of mesodermal cell differentiation,biological_process
93490,GO:1905773,Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.,8-hydroxy-2'-deoxyguanosine DNA binding,molecular_function
93491,GO:1905780,"Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.",regulation of phosphatidylserine exposure on apoptotic cell surface,biological_process
93492,GO:1905781,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.",negative regulation of phosphatidylserine exposure on apoptotic cell surface,biological_process
93493,GO:1905782,"Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.",positive regulation of phosphatidylserine exposure on apoptotic cell surface,biological_process
93494,GO:1905784,"Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.",regulation of anaphase-promoting complex-dependent catabolic process,biological_process
93495,GO:1905785,"Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.",negative regulation of anaphase-promoting complex-dependent catabolic process,biological_process
93496,GO:1905786,"Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.",positive regulation of anaphase-promoting complex-dependent catabolic process,biological_process
93497,GO:1905788,"Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.",negative regulation of detection of mechanical stimulus involved in sensory perception of touch,biological_process
93498,GO:1905789,"Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.",positive regulation of detection of mechanical stimulus involved in sensory perception of touch,biological_process
93499,GO:1905790,"Any process that modulates the frequency, rate or extent of mechanosensory behavior.",regulation of mechanosensory behavior,biological_process
93500,GO:1905791,"Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior.",negative regulation of mechanosensory behavior,biological_process
93501,GO:1905792,"Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.",positive regulation of mechanosensory behavior,biological_process
93502,GO:1905793,"A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.",protein localization to pericentriolar material,biological_process
93503,GO:1905794,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.",response to puromycin,biological_process
93504,GO:1905795,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.",cellular response to puromycin,biological_process
93505,GO:1905796,"Any process that modulates the frequency, rate or extent of intraciliary anterograde transport.",regulation of intraciliary anterograde transport,biological_process
93506,GO:1905797,"Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.",negative regulation of intraciliary anterograde transport,biological_process
93507,GO:1905798,"Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.",positive regulation of intraciliary anterograde transport,biological_process
93508,GO:1905799,"Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.",regulation of intraciliary retrograde transport,biological_process
93509,GO:1905800,"Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.",negative regulation of intraciliary retrograde transport,biological_process
93510,GO:1905801,"Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.",positive regulation of intraciliary retrograde transport,biological_process
93511,GO:1905802,"Any process that modulates the frequency, rate or extent of cellular response to manganese ion.",regulation of cellular response to manganese ion,biological_process
93512,GO:1905803,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.",negative regulation of cellular response to manganese ion,biological_process
93513,GO:1905804,"Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.",positive regulation of cellular response to manganese ion,biological_process
93514,GO:1905805,The disaggregation of an excitatory synapse into its constituent components.,excitatory synapse pruning,biological_process
93515,GO:1905806,"Any process that modulates the frequency, rate or extent of synapse pruning.",regulation of synapse pruning,biological_process
93516,GO:1905807,"Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning.",negative regulation of synapse pruning,biological_process
93517,GO:1905808,"Any process that activates or increases the frequency, rate or extent of synapse pruning.",positive regulation of synapse pruning,biological_process
93518,GO:1905809,"Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.",negative regulation of synapse organization,biological_process
93519,GO:1905810,"Any process that modulates the frequency, rate or extent of excitatory synapse pruning.",regulation of excitatory synapse pruning,biological_process
93520,GO:1905811,"Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.",negative regulation of excitatory synapse pruning,biological_process
93521,GO:1905812,"Any process that modulates the frequency, rate or extent of motor neuron axon guidance.",regulation of motor neuron axon guidance,biological_process
93522,GO:1905813,"Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance.",negative regulation of motor neuron axon guidance,biological_process
93523,GO:1905814,"Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.",positive regulation of motor neuron axon guidance,biological_process
93524,GO:1905815,"Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance.",regulation of dorsal/ventral axon guidance,biological_process
93525,GO:1905816,"Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance.",negative regulation of dorsal/ventral axon guidance,biological_process
93526,GO:1905817,"Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance.",positive regulation of dorsal/ventral axon guidance,biological_process
93527,GO:1905818,"Any process that modulates the frequency, rate or extent of chromosome separation.",regulation of chromosome separation,biological_process
93528,GO:1905819,"Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.",negative regulation of chromosome separation,biological_process
93529,GO:1905820,"Any process that activates or increases the frequency, rate or extent of chromosome separation.",positive regulation of chromosome separation,biological_process
93530,GO:1905821,"Any process that activates or increases the frequency, rate or extent of chromosome condensation.",positive regulation of chromosome condensation,biological_process
93531,GO:1905822,"Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation.",regulation of mitotic sister chromatid arm separation,biological_process
93532,GO:1905823,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation.",negative regulation of mitotic sister chromatid arm separation,biological_process
93533,GO:1905824,"Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation.",positive regulation of mitotic sister chromatid arm separation,biological_process
93534,GO:1905828,"Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.",regulation of prostaglandin catabolic process,biological_process
93535,GO:1905829,"Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.",negative regulation of prostaglandin catabolic process,biological_process
93536,GO:1905830,"Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process.",positive regulation of prostaglandin catabolic process,biological_process
93537,GO:1905831,"Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.",negative regulation of spindle assembly,biological_process
93538,GO:1905832,"Any process that activates or increases the frequency, rate or extent of spindle assembly.",positive regulation of spindle assembly,biological_process
93539,GO:1905833,"Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.",negative regulation of microtubule nucleation,biological_process
93540,GO:1905834,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.",response to pyrimidine ribonucleotide,biological_process
93541,GO:1905835,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.",cellular response to pyrimidine ribonucleotide,biological_process
93542,GO:1905836,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.",response to triterpenoid,biological_process
93543,GO:1905837,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.",cellular response to triterpenoid,biological_process
93544,GO:1905838,"Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.",regulation of telomeric D-loop disassembly,biological_process
93545,GO:1905839,"Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.",negative regulation of telomeric D-loop disassembly,biological_process
93546,GO:1905840,"Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.",positive regulation of telomeric D-loop disassembly,biological_process
93547,GO:1905841,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.",response to oxidopamine,biological_process
93548,GO:1905842,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.",cellular response to oxidopamine,biological_process
93549,GO:1905843,"Any process that modulates the frequency, rate or extent of cellular response to gamma radiation.",regulation of cellular response to gamma radiation,biological_process
93550,GO:1905844,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation.",negative regulation of cellular response to gamma radiation,biological_process
93551,GO:1905845,"Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.",positive regulation of cellular response to gamma radiation,biological_process
93552,GO:1905846,"Any process that modulates the frequency, rate or extent of cellular response to oxidopamine.",regulation of cellular response to oxidopamine,biological_process
93553,GO:1905847,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine.",negative regulation of cellular response to oxidopamine,biological_process
93554,GO:1905848,"Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine.",positive regulation of cellular response to oxidopamine,biological_process
93555,GO:1905849,"Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion.",negative regulation of forward locomotion,biological_process
93556,GO:1905850,"Any process that activates or increases the frequency, rate or extent of forward locomotion.",positive regulation of forward locomotion,biological_process
93557,GO:1905851,"Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion.",negative regulation of backward locomotion,biological_process
93558,GO:1905852,"Any process that activates or increases the frequency, rate or extent of backward locomotion.",positive regulation of backward locomotion,biological_process
93559,GO:1905856,"Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt.",negative regulation of pentose-phosphate shunt,biological_process
93560,GO:1905857,"Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt.",positive regulation of pentose-phosphate shunt,biological_process
93561,GO:1905861,"The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.",intranuclear rod assembly,biological_process
93562,GO:1905862,A protein complex which is capable of ferroxidase activity.,ferroxidase complex,cellular_component
93563,GO:1905864,"Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.",regulation of Atg1/ULK1 kinase complex assembly,biological_process
93564,GO:1905865,"Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.",negative regulation of Atg1/ULK1 kinase complex assembly,biological_process
93565,GO:1905866,"Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.",positive regulation of Atg1/ULK1 kinase complex assembly,biological_process
93566,GO:1905867,"The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.",epididymis development,biological_process
93567,GO:1905868,"Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.",regulation of 3'-UTR-mediated mRNA stabilization,biological_process
93568,GO:1905869,"Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.",negative regulation of 3'-UTR-mediated mRNA stabilization,biological_process
93569,GO:1905870,"Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.",positive regulation of 3'-UTR-mediated mRNA stabilization,biological_process
93570,GO:1905871,"Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.",regulation of protein localization to cell leading edge,biological_process
93571,GO:1905872,"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.",negative regulation of protein localization to cell leading edge,biological_process
93572,GO:1905873,"Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.",positive regulation of protein localization to cell leading edge,biological_process
93573,GO:1905874,"Any process that modulates the frequency, rate or extent of postsynaptic density organization.",regulation of postsynaptic density organization,biological_process
93574,GO:1905875,"Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.",negative regulation of postsynaptic density organization,biological_process
93575,GO:1905876,"Any process that activates or increases the frequency, rate or extent of postsynaptic density organization.",positive regulation of postsynaptic density organization,biological_process
93576,GO:1905879,"Any process that modulates the frequency, rate or extent of oogenesis.",regulation of oogenesis,biological_process
93577,GO:1905880,"Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.",negative regulation of oogenesis,biological_process
93578,GO:1905881,"Any process that activates or increases the frequency, rate or extent of oogenesis.",positive regulation of oogenesis,biological_process
93579,GO:1905883,"Any process that modulates the frequency, rate or extent of triglyceride transport.",regulation of triglyceride transport,biological_process
93580,GO:1905884,"Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport.",negative regulation of triglyceride transport,biological_process
93581,GO:1905885,"Any process that activates or increases the frequency, rate or extent of triglyceride transport.",positive regulation of triglyceride transport,biological_process
93582,GO:1905887,"The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing.",autoinducer AI-2 transmembrane transport,biological_process
93583,GO:1905888,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.",negative regulation of cellular response to very-low-density lipoprotein particle stimulus,biological_process
93584,GO:1905889,"Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.",positive regulation of cellular response to very-low-density lipoprotein particle stimulus,biological_process
93585,GO:1905890,"Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.",regulation of cellular response to very-low-density lipoprotein particle stimulus,biological_process
93586,GO:1905897,"Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.",regulation of response to endoplasmic reticulum stress,biological_process
93587,GO:1905898,"Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.",positive regulation of response to endoplasmic reticulum stress,biological_process
93588,GO:1905899,"Any process that modulates the frequency, rate or extent of smooth muscle tissue development.",regulation of smooth muscle tissue development,biological_process
93589,GO:1905900,"Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development.",negative regulation of smooth muscle tissue development,biological_process
93590,GO:1905901,"Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.",positive regulation of smooth muscle tissue development,biological_process
93591,GO:1905902,"Any process that modulates the frequency, rate or extent of mesoderm formation.",regulation of mesoderm formation,biological_process
93592,GO:1905903,"Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.",negative regulation of mesoderm formation,biological_process
93593,GO:1905904,"Any process that activates or increases the frequency, rate or extent of mesoderm formation.",positive regulation of mesoderm formation,biological_process
93594,GO:1905905,The developmental process by which a nematode pharyngeal gland is generated and organized.,nematode pharyngeal gland morphogenesis,biological_process
93595,GO:1905906,"Any process that modulates the frequency, rate or extent of amyloid fibril formation.",regulation of amyloid fibril formation,biological_process
93596,GO:1905907,"Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation.",negative regulation of amyloid fibril formation,biological_process
93597,GO:1905908,"Any process that activates or increases the frequency, rate or extent of amyloid fibril formation.",positive regulation of amyloid fibril formation,biological_process
93598,GO:1905909,"Any process that modulates the frequency, rate or extent of dauer entry.",regulation of dauer entry,biological_process
93599,GO:1905910,"Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry.",negative regulation of dauer entry,biological_process
93600,GO:1905911,"Any process that activates or increases the frequency, rate or extent of dauer entry.",positive regulation of dauer entry,biological_process
93601,GO:1905912,"Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.",regulation of calcium ion export across plasma membrane,biological_process
93602,GO:1905913,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.",negative regulation of calcium ion export across plasma membrane,biological_process
93603,GO:1905914,"Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.",positive regulation of calcium ion export across plasma membrane,biological_process
93604,GO:1905921,"Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.",regulation of acetylcholine biosynthetic process,biological_process
93605,GO:1905922,"Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.",negative regulation of acetylcholine biosynthetic process,biological_process
93606,GO:1905923,"Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.",positive regulation of acetylcholine biosynthetic process,biological_process
93607,GO:1905933,"Any process that modulates the frequency, rate or extent of cell fate determination.",regulation of cell fate determination,biological_process
93608,GO:1905934,"Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.",negative regulation of cell fate determination,biological_process
93609,GO:1905935,"Any process that activates or increases the frequency, rate or extent of cell fate determination.",positive regulation of cell fate determination,biological_process
93610,GO:1905936,"Any process that modulates the frequency, rate or extent of germ cell proliferation.",regulation of germ cell proliferation,biological_process
93611,GO:1905937,"Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.",negative regulation of germ cell proliferation,biological_process
93612,GO:1905938,"Any process that activates or increases the frequency, rate or extent of germ cell proliferation.",positive regulation of germ cell proliferation,biological_process
93613,GO:1905939,"Any process that modulates the frequency, rate or extent of gonad development.",regulation of gonad development,biological_process
93614,GO:1905940,"Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.",negative regulation of gonad development,biological_process
93615,GO:1905941,"Any process that activates or increases the frequency, rate or extent of gonad development.",positive regulation of gonad development,biological_process
93616,GO:1905942,"Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.",regulation of formation of growth cone in injured axon,biological_process
93617,GO:1905943,"Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon.",negative regulation of formation of growth cone in injured axon,biological_process
93618,GO:1905944,"Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon.",positive regulation of formation of growth cone in injured axon,biological_process
93619,GO:1905945,"Any process that modulates the frequency, rate or extent of response to calcium ion.",regulation of response to calcium ion,biological_process
93620,GO:1905946,"Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.",negative regulation of response to calcium ion,biological_process
93621,GO:1905947,"Any process that activates or increases the frequency, rate or extent of response to calcium ion.",positive regulation of response to calcium ion,biological_process
93622,GO:1905948,"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out).","ABC-type 3',5'-cyclic GMP transmembrane transporter activity",molecular_function
93623,GO:1905949,"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.",negative regulation of calcium ion import across plasma membrane,biological_process
93624,GO:1905951,Any DNA recombination that takes place in mitochondrion.,mitochondrion DNA recombination,biological_process
93625,GO:1905952,"Any process that modulates the frequency, rate or extent of lipid localization.",regulation of lipid localization,biological_process
93626,GO:1905953,"Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.",negative regulation of lipid localization,biological_process
93627,GO:1905954,"Any process that activates or increases the frequency, rate or extent of lipid localization.",positive regulation of lipid localization,biological_process
93628,GO:1905955,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.",negative regulation of endothelial tube morphogenesis,biological_process
93629,GO:1905956,"Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.",positive regulation of endothelial tube morphogenesis,biological_process
93630,GO:1905957,"Any process that modulates the frequency, rate or extent of cellular response to alcohol.",regulation of cellular response to alcohol,biological_process
93631,GO:1905958,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.",negative regulation of cellular response to alcohol,biological_process
93632,GO:1905959,"Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.",positive regulation of cellular response to alcohol,biological_process
93633,GO:1905960,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.",response to differentiation-inducing factor 2,biological_process
93634,GO:1905961,A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity.,protein-cysteine S-palmitoyltransferase complex,cellular_component
93635,GO:1905962,The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.,glutamatergic neuron differentiation,biological_process
93636,GO:1990000,"The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins.",amyloid fibril formation,biological_process
93637,GO:1990002,Catalysis of the reaction: hydroxyacetone + NADP+ = H+ + methylglyoxal + NADPH.,methylglyoxal reductase (NADPH) (acetol producing) activity,molecular_function
93638,GO:1990003,Catalysis of the reaction: IDP + H2O = IMP + H+ + phosphate.,IDP phosphatase activity,molecular_function
93639,GO:1990005,"A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.",granular vesicle,cellular_component
93640,GO:1990006,"A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.",amorphous vesicle,cellular_component
93641,GO:1990007,"A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.",membrane stack,cellular_component
93642,GO:1990008,"A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.",neurosecretory vesicle,cellular_component
93643,GO:1990009,Any apoptotic process in a retinal cell.,retinal cell apoptotic process,biological_process
93644,GO:1990010,Any apoptotic process in a compound eye retinal cell.,compound eye retinal cell apoptotic process,biological_process
93645,GO:1990011,Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.,laminated body,cellular_component
93646,GO:1990012,"A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.",complex laminated body,cellular_component
93647,GO:1990013,A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.,presynaptic grid,cellular_component
93648,GO:1990014,"Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).",orthogonal array,cellular_component
93649,GO:1990015,A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.,ensheathing process,cellular_component
93650,GO:1990016,"Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.",neck portion of tanycyte,cellular_component
93651,GO:1990017,"Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.",somatic portion of tanycyte,cellular_component
93652,GO:1990018,"Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.",tail portion of tanycyte,cellular_component
93653,GO:1990019,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.",protein storage vacuole organization,biological_process
93654,GO:1990020,Axon collateral that ramifies in the area of the soma of the cell of origin.,recurrent axon collateral,cellular_component
93655,GO:1990021,Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.,Schaffer axon collateral,cellular_component
93656,GO:1990023,"The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.",mitotic spindle midzone,cellular_component
93657,GO:1990024,Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.,C bouton,cellular_component
93658,GO:1990025,Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.,F bouton,cellular_component
93659,GO:1990026,Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.,hippocampal mossy fiber expansion,cellular_component
93660,GO:1990027,Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.,S bouton,cellular_component
93661,GO:1990028,Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.,intermediate voltage-gated calcium channel activity,molecular_function
93662,GO:1990029,"The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.",vasomotion,biological_process
93663,GO:1990030,"Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.",pericellular basket,cellular_component
93664,GO:1990031,Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.,pinceau fiber,cellular_component
93665,GO:1990032,"A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.",parallel fiber,cellular_component
93666,GO:1990033,"The part of a dendritic tree where it branches, giving rise to a dendritic branch.",dendritic branch point,cellular_component
93667,GO:1990034,"The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.",calcium ion export across plasma membrane,biological_process
93668,GO:1990036,The directed movement of calcium ions into a sarcoplasmic reticulum.,calcium ion import into sarcoplasmic reticulum,biological_process
93669,GO:1990037,"The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.",Lewy body core,cellular_component
93670,GO:1990038,"The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.",Lewy body corona,cellular_component
93671,GO:1990039,"Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.",hypolemmal cisterna,cellular_component
93672,GO:1990040,"Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.",sub-surface cisterna,cellular_component
93673,GO:1990044,"A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.",protein localization to lipid droplet,biological_process
93674,GO:1990045,"The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.",sclerotium development,biological_process
93675,GO:1990046,"Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.",stress-induced mitochondrial fusion,biological_process
93676,GO:1990047,"A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.",spindle matrix,cellular_component
93677,GO:1990048,The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.,anterograde neuronal dense core vesicle transport,biological_process
93678,GO:1990049,The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.,retrograde neuronal dense core vesicle transport,biological_process
93679,GO:1990050,"Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.",phosphatidic acid transfer activity,molecular_function
93680,GO:1990051,Any process that initiates the activity of the inactive enzyme protein kinase C.,activation of protein kinase C activity,biological_process
93681,GO:1990052,The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.,ER to chloroplast lipid transport,biological_process
93682,GO:1990053,"Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.",DNA-5-methylcytosine glycosylase activity,molecular_function
93683,GO:1990054,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.",response to temozolomide,biological_process
93684,GO:1990055,Catalyzes the reaction: L-phenylalanine + O2 + H2O + H+ = 2-phenylacetaldehyde + H2O2 + NH4+ + CO2.,phenylacetaldehyde synthase activity,molecular_function
93685,GO:1990058,"The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.",fruit replum development,biological_process
93686,GO:1990059,"The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.",fruit valve development,biological_process
93687,GO:1990060,"Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.",maltose transport complex,cellular_component
93688,GO:1990061,"The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.",bacterial degradosome,cellular_component
93689,GO:1990062,"A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.",RPAP3/R2TP/prefoldin-like complex,cellular_component
93690,GO:1990063,"Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.",Bam protein complex,cellular_component
93691,GO:1990064,The regionalization process that gives rise to the patterning of the ground tissue.,ground tissue pattern formation,biological_process
93692,GO:1990065,A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).,Dxr protein complex,cellular_component
93693,GO:1990066,The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.,energy quenching,biological_process
93694,GO:1990067,The process of DNA recombination occurring within a single chromosome.,intrachromosomal DNA recombination,biological_process
93695,GO:1990068,The seed development process whose outcome is the drying of a maturing seed.,seed dehydration,biological_process
93696,GO:1990069,"The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.",stomatal opening,biological_process
93697,GO:1990070,"A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.",TRAPPI protein complex,cellular_component
93698,GO:1990071,"A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.",TRAPPII protein complex,cellular_component
93699,GO:1990072,"A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.",TRAPPIII protein complex,cellular_component
93700,GO:1990073,A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).,perforation plate,cellular_component
93701,GO:1990074,"The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.",polyuridylation-dependent mRNA catabolic process,biological_process
93702,GO:1990075,A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.,periciliary membrane compartment,cellular_component
93703,GO:1990077,Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primos...,primosome complex,cellular_component
93704,GO:1990078,A protein complex that inhibits multiple events of replication initiation during one replication cycle.,replication inhibiting complex,cellular_component
93705,GO:1990079,"A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.",cartilage homeostasis,biological_process
93706,GO:1990080,Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.,2-phenylethylamine receptor activity,molecular_function
93707,GO:1990081,Combining with the biogenic amine trimethylamine to initiate a change in cell activity.,trimethylamine receptor activity,molecular_function
93708,GO:1990082,"A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.",DnaA-L2 complex,cellular_component
93709,GO:1990083,"A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.",DnaA-Hda complex,cellular_component
93710,GO:1990084,"A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.",DnaA-Dps complex,cellular_component
93711,GO:1990085,"A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.",Hda-beta clamp complex,cellular_component
93712,GO:1990086,"Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.",lens fiber cell apoptotic process,biological_process
93713,GO:1990088,Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+.,[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity,molecular_function
93714,GO:1990089,"A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.",response to nerve growth factor,biological_process
93715,GO:1990090,"A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.",cellular response to nerve growth factor stimulus,biological_process
93716,GO:1990091,The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.,sodium-dependent self proteolysis,biological_process
93717,GO:1990092,The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.,calcium-dependent self proteolysis,biological_process
93718,GO:1990097,"A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle.",SeqA-DNA complex,cellular_component
93719,GO:1990098,A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.,core primosome complex,cellular_component
93720,GO:1990099,"Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.",pre-primosome complex,cellular_component
93721,GO:1990100,"A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).",DnaB-DnaC complex,cellular_component
93722,GO:1990101,"A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.",DnaA-oriC complex,cellular_component
93723,GO:1990102,"A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.",DnaA-DiaA complex,cellular_component
93724,GO:1990103,A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.,DnaA-HU complex,cellular_component
93725,GO:1990104,A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.,DNA bending complex,cellular_component
93726,GO:1990107,"Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H+ + 2 H2O.",thiazole synthase activity,molecular_function
93727,GO:1990108,"A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.",protein linear deubiquitination,biological_process
93728,GO:1990109,The recognition and rejection of pollen of one species by cells in the stigma of another species.,rejection of pollen from other species,biological_process
93729,GO:1990110,The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.,callus formation,biological_process
93730,GO:1990111,"A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.",spermatoproteasome complex,cellular_component
93731,GO:1990112,"A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.",RQC complex,cellular_component
93732,GO:1990113,"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.",RNA polymerase I assembly,biological_process
93733,GO:1990114,"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.",RNA polymerase II core complex assembly,biological_process
93734,GO:1990115,"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.",RNA polymerase III assembly,biological_process
93735,GO:1990116,"The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.",ribosome-associated ubiquitin-dependent protein catabolic process,biological_process
93736,GO:1990117,An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.,B cell receptor apoptotic signaling pathway,biological_process
93737,GO:1990119,"Binds to and stops, prevents or reduces the activity of an RNA helicase.",RNA helicase inhibitor activity,molecular_function
93738,GO:1990121,A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.,H-NS complex,cellular_component
93739,GO:1990125,A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.,DiaA complex,cellular_component
93740,GO:1990127,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator,biological_process
93741,GO:1990130,"A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.",GATOR1 complex,cellular_component
93742,GO:1990131,"A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.",Gtr1-Gtr2 GTPase complex,cellular_component
93743,GO:1990133,A heterotetrameric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; in human the subunits are MOCS3 and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.,molybdopterin adenylyltransferase complex,cellular_component
93744,GO:1990134,An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.,epithelial cell apoptotic process involved in palatal shelf morphogenesis,biological_process
93745,GO:1990135,"Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.",flavonoid sulfotransferase activity,molecular_function
93746,GO:1990136,"Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.",linoleate 9S-lipoxygenase activity,molecular_function
93747,GO:1990137,Catalysis of the reaction: RH + ROOH = ROH + ROH.,plant seed peroxygenase activity,molecular_function
93748,GO:1990138,"Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.",neuron projection extension,biological_process
93749,GO:1990139,"A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.",protein localization to nuclear periphery,biological_process
93750,GO:1990140,"A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.",molybdopterin synthase complex,cellular_component
93751,GO:1990143,"A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway.",CoA-synthesizing protein complex,cellular_component
93752,GO:1990144,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.",intrinsic apoptotic signaling pathway in response to hypoxia,biological_process
93753,GO:1990145,"Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.",maintenance of translational fidelity,biological_process
93754,GO:1990146,"A process in which a protein is transported to, or maintained in, a location within a rhabdomere.",protein localization to rhabdomere,biological_process
93755,GO:1990147,"Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.",talin binding,molecular_function
93756,GO:1990148,A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.,glutamate dehydrogenase complex,cellular_component
93757,GO:1990150,"A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.",VEGF-A complex,cellular_component
93758,GO:1990151,"A process in which a protein is transported to, or maintained in, a location at the cell tip.",protein localization to cell tip,biological_process
93759,GO:1990153,A process in which a protein is maintained in a location in telomeric heterochromatin.,maintenance of protein localization to heterochromatin,biological_process
93760,GO:1990154,"A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.",enzyme IIA-maltose transporter complex,cellular_component
93761,GO:1990155,"The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.",Dsc E3 ubiquitin ligase complex assembly,biological_process
93762,GO:1990156,"A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.",DnaB-DnaG complex,cellular_component
93763,GO:1990157,A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.,DnaA-DnaB-DnaC complex,cellular_component
93764,GO:1990158,"A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.",DnaB-DnaC-DnaT-PriA-PriB complex,cellular_component
93765,GO:1990159,"A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.",DnaB-DnaC-DnaT-PriA-PriC complex,cellular_component
93766,GO:1990160,"A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.",DnaB-DnaC-Rep-PriC complex,cellular_component
93767,GO:1990161,A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.,DnaB helicase complex,cellular_component
93768,GO:1990162,Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.,"histone H3K4 deacetylase activity, hydrolytic mechanism",molecular_function
93769,GO:1990165,Binding to damaged DNA containing single-strand breaks (SSBs).,single-strand break-containing DNA binding,molecular_function
93770,GO:1990166,"Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.",protein localization to site of double-strand break,biological_process
93771,GO:1990167,"A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.",protein K27-linked deubiquitination,biological_process
93772,GO:1990168,"A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.",protein K33-linked deubiquitination,biological_process
93773,GO:1990169,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.",stress response to copper ion,biological_process
93774,GO:1990170,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.",stress response to cadmium ion,biological_process
93775,GO:1990171,The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.,SCF complex disassembly in response to cadmium stress,biological_process
93776,GO:1990172,The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.,G protein-coupled receptor catabolic process,biological_process
93777,GO:1990173,"A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.",protein localization to nucleoplasm,biological_process
93778,GO:1990174,Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.,phosphodiesterase decapping endonuclease activity,molecular_function
93779,GO:1990175,Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.,EH domain binding,molecular_function
93780,GO:1990176,"Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.",MalFGK2 complex,cellular_component
93781,GO:1990177,"A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.",IHF-DNA complex,cellular_component
93782,GO:1990178,A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.,HU-DNA complex,cellular_component
93783,GO:1990179,"A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.",protein localization to actomyosin contractile ring,biological_process
93784,GO:1990180,The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.,mitochondrial tRNA 3'-end processing,biological_process
93785,GO:1990182,The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.,exosomal secretion,biological_process
93786,GO:1990183,A circulatory process that occurs at the level of the lymphatic vasculature.,lymphatic vascular process in circulatory system,biological_process
93787,GO:1990184,A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.,amino acid transport complex,cellular_component
93788,GO:1990185,Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.,regulation of lymphatic vascular permeability,biological_process
93789,GO:1990186,Any process that modulates the size of lymphatic vessels.,regulation of lymphatic vessel size,biological_process
93790,GO:1990188,"Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.",euchromatin binding,molecular_function
93791,GO:1990189,Catalysis of the reaction: acetyl-CoA + N-terminal L-seryl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-seryl-[protein].,protein N-terminal-serine acetyltransferase activity,molecular_function
93792,GO:1990190,Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.,protein-N-terminal-glutamate acetyltransferase activity,molecular_function
93793,GO:1990191,"Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.",cobalamin transport complex,cellular_component
93794,GO:1990192,A decrease in the diameter of collecting lymphatic vessels.,collecting lymphatic vessel constriction,biological_process
93795,GO:1990193,"Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.",BtuCD complex,cellular_component
93796,GO:1990194,"The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.",cytoplasmic U snRNP body assembly,biological_process
93797,GO:1990195,"A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC...",macrolide transmembrane transporter complex,cellular_component
93798,GO:1990196,"The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.",MacAB-TolC complex,cellular_component
93799,GO:1990197,"An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner.",methionine-importing ABC transporter complex,cellular_component
93800,GO:1990198,"A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.",ModE complex,cellular_component
93801,GO:1990199,"An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).",MsbA transporter complex,cellular_component
93802,GO:1990200,A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.,SsuD-SsuE complex,cellular_component
93803,GO:1990201,"A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.",alkanesulfonate monooxygenase complex,cellular_component
93804,GO:1990202,"A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.",FMN reductase complex,cellular_component
93805,GO:1990203,A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.,MdtBC Complex,cellular_component
93806,GO:1990204,Any protein complex that possesses oxidoreductase activity.,oxidoreductase complex,cellular_component
93807,GO:1990205,"A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.",taurine dioxygenase complex,cellular_component
93808,GO:1990206,Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.,jasmonyl-Ile conjugate hydrolase activity,molecular_function
93809,GO:1990207,"A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.",EmrE multidrug transporter complex,cellular_component
93810,GO:1990215,A process in which a symbiont alters or subverts vesicle-mediated transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated perturbation of host vesicle-mediated transport,biological_process
93811,GO:1990216,"A process in which a symbiont initiates, promotes, or enhances transcription of genes into mRNA in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.",symbiont-mediated activation of host transcription,biological_process
93812,GO:1990217,A process in which a symbiont inhibits or disrupts the production of phytoalexins in the host organism. Phytoalexins are produced by plants to fight against pathogens. The host is defined as the larger of the organisms involved in a symbiotic interaction.,symbiont-mediated suppression of host phytoalexin production,biological_process
93813,GO:1990220,Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.,GroEL-GroES complex,cellular_component
93814,GO:1990221,A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes.,L-cysteine desulfurase complex,cellular_component
93815,GO:1990222,"The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions.",ProVWX complex,cellular_component
93816,GO:1990225,"Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.",rhoptry neck,cellular_component
93817,GO:1990226,Binding to a histone methyltransferase enzyme.,histone methyltransferase binding,molecular_function
93818,GO:1990227,"The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.",paranodal junction maintenance,biological_process
93819,GO:1990228,A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).,sulfurtransferase complex,cellular_component
93820,GO:1990229,A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.,iron-sulfur cluster assembly complex,cellular_component
93821,GO:1990230,"A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor), which may be a target protein or another Fe-S assembly complex. In humans, it consists of HSPA9, HSCB, GLRX5, ABCB7 and GFER.",iron-sulfur cluster transfer complex,cellular_component
93822,GO:1990231,"A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.",STING complex,cellular_component
93823,GO:1990232,A protein complex capable of phosphomannomutase activity.,phosphomannomutase complex,cellular_component
93824,GO:1990233,A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.,intramolecular phosphotransferase complex,cellular_component
93825,GO:1990234,"A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).",transferase complex,cellular_component
93826,GO:1990235,A protein complex which is capable of diamine N-acetyltransferase activity.,diamine N-acetyltransferase complex,cellular_component
93827,GO:1990236,The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.,proteasome core complex import into nucleus,biological_process
93828,GO:1990238,Catalysis of the hydrolysis of ester linkages within a double-stranded DNA molecule by creating internal breaks.,double-stranded DNA endonuclease activity,molecular_function
93829,GO:1990239,Binding to a steroid hormone.,steroid hormone binding,molecular_function
93830,GO:1990243,A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).,atf1-pcr1 complex,cellular_component
93831,GO:1990244,Catalysis of the reaction: histone H2A-threonine (position 120) + ATP = histone H2A-phosphothreonine (position 120) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 120 of histone H2A.,histone H2AT120 kinase activity,molecular_function
93832,GO:1990246,"A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.",uniplex complex,cellular_component
93833,GO:1990247,"A protein adaptor that recognizes and binds an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.",N6-methyladenosine-containing RNA reader activity,molecular_function
93834,GO:1990249,"A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.","nucleotide-excision repair, DNA damage recognition complex",cellular_component
93835,GO:1990250,"A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.","transcription-coupled nucleotide-excision repair, DNA damage recognition complex",cellular_component
93836,GO:1990251,"An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.",nuclear exosome focus,cellular_component
93837,GO:1990252,A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.,Syp1 complex,cellular_component
93838,GO:1990253,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.",cellular response to leucine starvation,biological_process
93839,GO:1990254,"Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.",keratin filament binding,molecular_function
93840,GO:1990255,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.",subsynaptic reticulum organization,biological_process
93841,GO:1990256,Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.,signal clustering,biological_process
93842,GO:1990257,"A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the...",piccolo-bassoon transport vesicle,cellular_component
93843,GO:1990259,Catalysis of the reaction: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine + H+. Note that this corresponds to Q105 in yeast.,histone H2AQ104 methyltransferase activity,molecular_function
93844,GO:1990261,The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).,pre-mRNA catabolic process,biological_process
93845,GO:1990262,"The series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Upon ligand binding, the receptor  forms a complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.",anti-Mullerian hormone receptor signaling pathway,biological_process
93846,GO:1990264,Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.,peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity,biological_process
93847,GO:1990265,"A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).",platelet-derived growth factor complex,cellular_component
93848,GO:1990266,The movement of a neutrophil within or between different tissues and organs of the body.,neutrophil migration,biological_process
93849,GO:1990267,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.",response to transition metal nanoparticle,biological_process
93850,GO:1990268,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.",response to gold nanoparticle,biological_process
93851,GO:1990269,Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II.,RNA polymerase II C-terminal domain phosphoserine binding,molecular_function
93852,GO:1990270,"A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations ...",platelet-derived growth factor receptor-ligand complex,cellular_component
93853,GO:1990272,Combining with anti-Mullerian hormone to initiate a change in cell activity.,anti-Mullerian hormone receptor activity,molecular_function
93854,GO:1990273,"The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed U6 snRNA is also TMG capped.","snRNA 2,2,7-trimethylguanosine (TMG) capping",biological_process
93855,GO:1990275,Binding to a preribosome.,preribosome binding,molecular_function
93856,GO:1990276,Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.,RNA 5'-gamma-phosphate methyltransferase activity,molecular_function
93857,GO:1990277,"A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells.",parasexual reproduction with cellular fusion,biological_process
93858,GO:1990280,A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.,RNA localization to chromatin,biological_process
93859,GO:1990281,A protein complex that is capable of efflux transmembrane transporter activity.,efflux pump complex,cellular_component
93860,GO:1990295,"A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.",post-anaphase microtubule array,cellular_component
93861,GO:1990297,"A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.",renal amino acid absorption,biological_process
93862,GO:1990298,Protein complex that associates with the kinetochores.,bub1-bub3 complex,cellular_component
93863,GO:1990299,"A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.",Bub1-Bub3 complex localization to kinetochore,biological_process
93864,GO:1990300,"Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.",cellulosome binding,molecular_function
93865,GO:1990302,"A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.",Bre1-Rad6 ubiquitin ligase complex,cellular_component
93866,GO:1990303,"A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.",UBR1-RAD6 ubiquitin ligase complex,cellular_component
93867,GO:1990304,"A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.",MUB1-RAD6-UBR2 ubiquitin ligase complex,cellular_component
93868,GO:1990305,A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.,RAD6-UBR2 ubiquitin ligase complex,cellular_component
93869,GO:1990306,"A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.",RSP5-BUL ubiquitin ligase complex,cellular_component
93870,GO:1990308,Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.,type-I dockerin domain binding,molecular_function
93871,GO:1990309,Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.,type-II dockerin domain binding,molecular_function
93872,GO:1990310,Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.,type-III dockerin domain binding,molecular_function
93873,GO:1990311,Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.,type-I cohesin domain binding,molecular_function
93874,GO:1990312,Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.,type-II cohesin domain binding,molecular_function
93875,GO:1990313,Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.,type-III cohesin domain binding,molecular_function
93876,GO:1990314,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.",cellular response to insulin-like growth factor stimulus,biological_process
93877,GO:1990315,A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.,Mcs4 RR-MAPKKK complex,cellular_component
93878,GO:1990316,"A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.",Atg1/ULK1 kinase complex,cellular_component
93879,GO:1990317,"A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.",Gin4 complex,cellular_component
93880,GO:1990318,"A collagen homotrimer made of three alpha1(XIX) collagen chains, each presenting interrupted triple helical collagen domains. Localizes to basement membrane ECMs, not known to associate with any fibrillar collagens that are predominantly found in the interstitial extracellular matrix.",collagen type XIX trimer,cellular_component
93881,GO:1990319,A collagen homotrimer of alpha1(XX) chains.,collagen type XX trimer,cellular_component
93882,GO:1990320,A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.,collagen type XXI trimer,cellular_component
93883,GO:1990321,A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.,collagen type XXII trimer,cellular_component
93884,GO:1990322,A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.,collagen type XXIII trimer,cellular_component
93885,GO:1990323,A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.,collagen type XXIV trimer,cellular_component
93886,GO:1990324,A collagen homotrimer of alpha1(XXVI) chains.,collagen type XXVI trimer,cellular_component
93887,GO:1990325,"A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.",collagen type XXVII trimer,cellular_component
93888,GO:1990326,A collagen homotrimer of alpha1(XXVIII) chains.,collagen type XXVIII trimer,cellular_component
93889,GO:1990327,A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.,collagen type XXV trimer,cellular_component
93890,GO:1990328,A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.,RPB4-RPB7 complex,cellular_component
93891,GO:1990329,A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.,IscS-TusA complex,cellular_component
93892,GO:1990330,A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consists of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.,IscS-IscU complex,cellular_component
93893,GO:1990331,"A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.",Hpa2 acetyltransferase complex,cellular_component
93894,GO:1990332,"A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base...",Ire1 complex,cellular_component
93895,GO:1990333,"A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.","mitotic checkpoint complex, CDC20-MAD2 subcomplex",cellular_component
93896,GO:1990334,"A protein complex that acts as a two-component GTPase-activating protein for the Tem1/Spg1 GTPase, thus regulating a signal transduction cascade (the mitotic exit network, MEN, in budding yeast; the septation initiation network, SIN, in fission yeast), which is required for mitotic exit and cytokinesis. The complex keeps the GTPase inactive until the spindle is properly oriented, thus inhibiting MEN/SIN activation.",SIN/MEN two-component GAP complex,cellular_component
93897,GO:1990338,"A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.",laminin-423 trimer,cellular_component
93898,GO:1990339,"A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.",laminin-522 trimer,cellular_component
93899,GO:1990340,"A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.",laminin-523 trimer,cellular_component
93900,GO:1990341,"A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.",thrombospondin complex,cellular_component
93901,GO:1990342,"A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.",heterochromatin island,cellular_component
93902,GO:1990343,"A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).",heterochromatin domain,cellular_component
93903,GO:1990344,"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.",secondary cell septum biogenesis,biological_process
93904,GO:1990346,"A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.",BID-BCL-xl complex,cellular_component
93905,GO:1990349,"The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.",gap junction-mediated intercellular transport,biological_process
93906,GO:1990350,"A protein complex facilitating glucose transport into, out of or within a cell, or between cells.",glucose transporter complex,cellular_component
93907,GO:1990351,"A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.",transporter complex,cellular_component
93908,GO:1990352,A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.,BRE1 E3 ubiquitin ligase complex,cellular_component
93909,GO:1990353,"A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.",Fused-Smurf ubiquitin ligase complex,cellular_component
93910,GO:1990354,A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.,activated SUMO-E1 ligase complex,cellular_component
93911,GO:1990357,"An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.",terminal web,cellular_component
93912,GO:1990358,"A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.",xylanosome,cellular_component
93913,GO:1990359,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.",stress response to zinc ion,biological_process
93914,GO:1990360,"A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.",PKM2 protein kinase complex,cellular_component
93915,GO:1990361,"A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).",PKM2 pyruvate kinase complex,cellular_component
93916,GO:1990362,Catalysis of the reaction: butan-1-ol + NAD+ = butanal + H+ + NADH.,butanol dehydrogenase (NAD+) activity,molecular_function
93917,GO:1990374,A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.,Kir2 inward rectifier potassium channel complex,cellular_component
93918,GO:1990375,"The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.",baculum development,biological_process
93919,GO:1990377,An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.,organomineral extracellular matrix,cellular_component
93920,GO:1990378,A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.,upstream stimulatory factor complex,cellular_component
93921,GO:1990379,The directed movement of lipid molecules passing through the blood-brain barrier.,lipid transport across blood-brain barrier,biological_process
93922,GO:1990380,Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin.,K48-linked deubiquitinase activity,molecular_function
93923,GO:1990381,Binding to a ubiquitin-specific protease.,ubiquitin-specific protease binding,molecular_function
93924,GO:1990383,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.",cellular response to biotin starvation,biological_process
93925,GO:1990384,The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.,hyaloid vascular plexus regression,biological_process
93926,GO:1990385,The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.,meiotic spindle midzone,cellular_component
93927,GO:1990386,Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.,mitotic cleavage furrow ingression,biological_process
93928,GO:1990387,"The chemical reactions and pathways resulting in the formation of isogobliosides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,3Gal-alpha-1,3Gal-beta-1,4Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units.",isogloboside biosynthetic process,biological_process
93929,GO:1990388,The directed movement of iron ions into the phloem from the xylem.,xylem-to-phloem iron transport,biological_process
93930,GO:1990389,"A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.",CUE1-UBC7 ubiquitin-conjugating enzyme complex,cellular_component
93931,GO:1990390,"A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.",protein K33-linked ubiquitination,biological_process
93932,GO:1990391,"A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.",DNA repair complex,cellular_component
93933,GO:1990392,"A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.",EFF-1 complex,cellular_component
93934,GO:1990393,"A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.",3M complex,cellular_component
93935,GO:1990394,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.",cellular response to cell wall damage,biological_process
93936,GO:1990395,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.",meiotic spindle pole body organization,biological_process
93937,GO:1990396,"The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.",single-strand break repair via homologous recombination,biological_process
93938,GO:1990398,"Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth.",Cus cation efflux complex,cellular_component
93939,GO:1990399,The regrowth of lost or destroyed epithelium.,epithelium regeneration,biological_process
93940,GO:1990400,Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).,mitochondrial ribosomal large subunit rRNA binding,molecular_function
93941,GO:1990401,"The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.",embryonic lung development,biological_process
93942,GO:1990402,"The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.",embryonic liver development,biological_process
93943,GO:1990403,"The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.",embryonic brain development,biological_process
93944,GO:1990404,Catalysis of the reaction: amino acyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-amino acyl-[protein] + nicotinamide.,NAD+-protein mono-ADP-ribosyltransferase activity,molecular_function
93945,GO:1990405,Binding to a protein antigen.,protein antigen binding,molecular_function
93946,GO:1990406,"A transmembrane, G protein-coupled signaling receptor complex recognized by calcitonin gene-related peptides (CGRP).",CGRP receptor complex,cellular_component
93947,GO:1990407,Binding to calcitonin gene-related peptide (CGRP).,calcitonin gene-related peptide binding,molecular_function
93948,GO:1990408,"The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.",calcitonin gene-related peptide receptor signaling pathway,biological_process
93949,GO:1990409,Binding to adrenomedullin (AM).,adrenomedullin binding,molecular_function
93950,GO:1990410,The series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.,adrenomedullin receptor signaling pathway,biological_process
93951,GO:1990411,Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.,hercynylcysteine sulfoxide lyase activity (ergothioneine-forming),molecular_function
93952,GO:1990413,A small pigmented organelle used in single-celled organisms to detect light.,eyespot apparatus,cellular_component
93953,GO:1990414,The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.,replication-born double-strand break repair via sister chromatid exchange,biological_process
93954,GO:1990416,"A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus.",cellular response to brain-derived neurotrophic factor stimulus,biological_process
93955,GO:1990417,The release of snoRNA from pre-rRNA.,snoRNA release from pre-rRNA,biological_process
93956,GO:1990418,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.",response to insulin-like growth factor stimulus,biological_process
93957,GO:1990422,Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.,glyoxalase (glycolic acid-forming) activity,molecular_function
93958,GO:1990423,A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.,RZZ complex,cellular_component
93959,GO:1990424,Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.,protein arginine kinase activity,molecular_function
93960,GO:1990425,"A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.",ryanodine receptor complex,cellular_component
93961,GO:1990426,Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.,mitotic recombination-dependent replication fork processing,biological_process
93962,GO:1990427,An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.,stereocilia tip-link density,cellular_component
93963,GO:1990428,"The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.",miRNA transport,biological_process
93964,GO:1990429,A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.,peroxisomal importomer complex,cellular_component
93965,GO:1990430,Binding to a protein that is part of an extracellular matrix.,extracellular matrix protein binding,molecular_function
93966,GO:1990431,The process of forming the mature 3' end of a priRNA molecule.,priRNA 3'-end processing,biological_process
93967,GO:1990432,The process of forming the mature 3' end of a siRNA molecule.,siRNA 3'-end processing,biological_process
93968,GO:1990433,"A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes.",CSL-Notch-Mastermind transcription factor complex,cellular_component
93969,GO:1990434,An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.,lower tip-link density,cellular_component
93970,GO:1990435,An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.,upper tip-link density,cellular_component
93971,GO:1990437,The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.,snRNA 2'-O-methylation,biological_process
93972,GO:1990438,The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.,U6 2'-O-snRNA methylation,biological_process
93973,GO:1990439,Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.,MAP kinase serine/threonine phosphatase activity,molecular_function
93974,GO:1990442,"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.",intrinsic apoptotic signaling pathway in response to nitrosative stress,biological_process
93975,GO:1990443,"The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.",peptidyl-threonine autophosphorylation,biological_process
93976,GO:1990444,Binding to an F-box domain of a protein.,F-box domain binding,molecular_function
93977,GO:1990446,Binding to a U1 small nuclear ribonucleoprotein particle.,U1 snRNP binding,molecular_function
93978,GO:1990447,Binding to a U2 small nuclear ribonucleoprotein particle.,U2 snRNP binding,molecular_function
93979,GO:1990448,"Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.",exon-exon junction complex binding,molecular_function
93980,GO:1990450,Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.,linear polyubiquitin binding,molecular_function
93981,GO:1990451,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.",cellular stress response to acidic pH,biological_process
93982,GO:1990452,"A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.",Parkin-FBXW7-Cul1 ubiquitin ligase complex,cellular_component
93983,GO:1990453,A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.,TINTIN complex,cellular_component
93984,GO:1990454,"A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.",L-type voltage-gated calcium channel complex,cellular_component
93985,GO:1990455,"A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.",PTEN phosphatase complex,cellular_component
93986,GO:1990457,A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.,pexophagosome,cellular_component
93987,GO:1990458,Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.,lipooligosaccharide binding,molecular_function
93988,GO:1990459,Binding to a transferrin receptor.,transferrin receptor binding,molecular_function
93989,GO:1990460,Binding to a leptin receptor.,leptin receptor binding,molecular_function
93990,GO:1990461,Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.,detoxification of iron ion,biological_process
93991,GO:1990462,Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.,omegasome,cellular_component
93992,GO:1990463,"A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins.",lateral cortical node,cellular_component
93993,GO:1990464,Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol.,(2R)-hydroxyacid dehydrogenase (quinone) activity,molecular_function
93994,GO:1990466,"The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.",protein autosumoylation,biological_process
93995,GO:1990467,"A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.",NuA3a histone acetyltransferase complex,cellular_component
93996,GO:1990468,"A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.",NuA3b histone acetyltransferase complex,cellular_component
93997,GO:1990469,"Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.",Rhino-Deadlock-Cutoff Complex,cellular_component
93998,GO:1990470,"Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).",piRNA cluster binding,molecular_function
93999,GO:1990471,"Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.",piRNA uni-strand cluster binding,molecular_function
94000,GO:1990472,"Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.",piRNA dual-strand cluster binding,molecular_function
94001,GO:1990474,"A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.","synaptic vesicle, readily releasable pool",cellular_component
94002,GO:1990475,"A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state.","synaptic vesicle, recycling pool",cellular_component
94003,GO:1990476,A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.,"synaptic vesicle, resting pool",cellular_component
94004,GO:1990477,"Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex.",MTREC complex,cellular_component
94005,GO:1990478,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.",response to ultrasound,biological_process
94006,GO:1990481,The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.,mRNA pseudouridine synthesis,biological_process
94007,GO:1990482,Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.,sphingolipid alpha-glucuronosyltransferase activity,molecular_function
94008,GO:1990484,The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.,aerobic lactate catabolic process,biological_process
94009,GO:1990485,The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.,anaerobic lactate catabolic process,biological_process
94010,GO:1990487,The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.,anaerobic lignin catabolic process,biological_process
94011,GO:1990488,"The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.",anaerobic cellulose catabolic process,biological_process
94012,GO:1990490,"A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.",archaeal proton-transporting A-type ATPase complex,cellular_component
94013,GO:1990497,"Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",regulation of cytoplasmic translation in response to stress,biological_process
94014,GO:1990498,Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.,mitotic spindle microtubule,cellular_component
94015,GO:1990499,"Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).",raps-insc complex,cellular_component
94016,GO:1990500,"A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.",eif4e-cup complex,cellular_component
94017,GO:1990501,"Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.",exon-exon junction subcomplex mago-y14,cellular_component
94018,GO:1990502,Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.,dense core granule maturation,biological_process
94019,GO:1990503,A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.,dendritic lamellar body,cellular_component
94020,GO:1990504,"The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.",dense core granule exocytosis,biological_process
94021,GO:1990505,Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication.,mitotic DNA replication maintenance of fidelity,biological_process
94022,GO:1990506,A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.,mitotic DNA-templated DNA replication,biological_process
94023,GO:1990508,"Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.",CKM complex,cellular_component
94024,GO:1990509,"Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans.",PYM-mago-Y14 complex,cellular_component
94025,GO:1990512,Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.,Cry-Per complex,cellular_component
94026,GO:1990513,"Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.",CLOCK-BMAL transcription complex,cellular_component
94027,GO:1990514,"An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.",5' transitive RNA interference,biological_process
94028,GO:1990515,"An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.",3' transitive RNA interference,biological_process
94029,GO:1990516,"The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.",ribonucleotide excision repair,biological_process
94030,GO:1990518,"Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.",single-stranded 3'-5' DNA helicase activity,molecular_function
94031,GO:1990519,"The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix.",pyrimidine nucleotide import into mitochondrion,biological_process
94032,GO:1990520,"A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC).",separase-securin complex,cellular_component
94033,GO:1990522,"The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.",tail spike morphogenesis,biological_process
94034,GO:1990523,The regrowth of bone following its loss or destruction.,bone regeneration,biological_process
94035,GO:1990524,"A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.",INA complex,cellular_component
94036,GO:1990525,Binding to a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.,BIR domain binding,molecular_function
94037,GO:1990526,A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.,Ste12p-Dig1p-Dig2p complex,cellular_component
94038,GO:1990527,"A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.",Tec1p-Ste12p-Dig1p complex,cellular_component
94039,GO:1990528,A protein complex that is involved in endocytosis in the yeast S. cerevisiae.,Rvs161p-Rvs167p complex,cellular_component
94040,GO:1990529,A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M.,glycosylphosphatidylinositol-mannosyltransferase I complex,cellular_component
94041,GO:1990530,"A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.",Cdc50p-Drs2p complex,cellular_component
94042,GO:1990531,A protein complex that functions as a phospholipid-translocating P-Type ATPase.,phospholipid-translocating ATPase complex,cellular_component
94043,GO:1990532,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.",stress response to nickel ion,biological_process
94044,GO:1990533,"A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.",Dom34-Hbs1 complex,cellular_component
94045,GO:1990534,Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.,thermospermine oxidase activity,molecular_function
94046,GO:1990535,"The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.",neuron projection maintenance,biological_process
94047,GO:1990536,The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.,phosphoenolpyruvate transmembrane import into Golgi lumen,biological_process
94048,GO:1990537,Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.,mitotic spindle polar microtubule,cellular_component
94049,GO:1990538,Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.,xylan O-acetyltransferase activity,molecular_function
94050,GO:1990539,"The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.",fructose import across plasma membrane,biological_process
94051,GO:1990540,"The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial manganese ion transmembrane transport,biological_process
94052,GO:1990542,"The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.",mitochondrial transmembrane transport,biological_process
94053,GO:1990543,"The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial S-adenosyl-L-methionine transmembrane transport,biological_process
94054,GO:1990544,"The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial ATP transmembrane transport,biological_process
94055,GO:1990545,"The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial thiamine pyrophosphate transmembrane transport,biological_process
94056,GO:1990546,"The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial tricarboxylic acid transmembrane transport,biological_process
94057,GO:1990547,"The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial phosphate ion transmembrane transport,biological_process
94058,GO:1990548,"The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial FAD transmembrane transport,biological_process
94059,GO:1990549,"The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial NAD transmembrane transport,biological_process
94060,GO:1990550,"The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial alpha-ketoglutarate transmembrane transport,biological_process
94061,GO:1990551,"The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial 2-oxoadipate transmembrane transport,biological_process
94062,GO:1990553,"The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial 5'-adenylyl sulfate transmembrane transport,biological_process
94063,GO:1990554,"The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport,biological_process
94064,GO:1990555,"The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial oxaloacetate transmembrane transport,biological_process
94065,GO:1990556,"The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial isopropylmalate transmembrane transport,biological_process
94066,GO:1990557,"The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial sulfate transmembrane transport,biological_process
94067,GO:1990558,"The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial malonate(1-) transmembrane transport,biological_process
94068,GO:1990559,"The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial coenzyme A transmembrane transport,biological_process
94069,GO:1990562,An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery.,syndecan-syntenin-ALIX complex,cellular_component
94070,GO:1990563,A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome.,extracellular exosome complex,cellular_component
94071,GO:1990564,"Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain.",protein polyufmylation,biological_process
94072,GO:1990565,"A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signaling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 cr...",HSP90-CDC37 chaperone complex,cellular_component
94073,GO:1990566,"An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.",I(KACh) inward rectifier potassium channel complex,cellular_component
94074,GO:1990567,"A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.",DPS complex,cellular_component
94075,GO:1990569,The process in which UDP-N-acetylglucosamine is transported across a membrane.,UDP-N-acetylglucosamine transmembrane transport,biological_process
94076,GO:1990570,The process in which GDP-mannose is transported across a membrane.,GDP-mannose transmembrane transport,biological_process
94077,GO:1990571,The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I.,meiotic centromere clustering,biological_process
94078,GO:1990572,"A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP).",TERT-RMRP complex,cellular_component
94079,GO:1990573,"The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.",potassium ion import across plasma membrane,biological_process
94080,GO:1990574,Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.,meiotic spindle astral microtubule,cellular_component
94081,GO:1990575,"The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion.",mitochondrial L-ornithine transmembrane transport,biological_process
94082,GO:1990576,Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.,G protein-coupled glucose receptor activity,molecular_function
94083,GO:1990577,The removal of a methyl group from the C-terminal amino acid of a protein.,C-terminal protein demethylation,biological_process
94084,GO:1990578,"The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.",perinuclear endoplasmic reticulum membrane,cellular_component
94085,GO:1990580,"Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.",regulation of cytoplasmic translational termination,biological_process
94086,GO:1990583,Binds to and increases the activity of the enzyme phospholipase D.,phospholipase D activator activity,molecular_function
94087,GO:1990584,"A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.",cardiac Troponin complex,cellular_component
94088,GO:1990585,Catalysis of the reaction: trans-4-hydroxy-L-prolyl-[protein] + UDP-beta-L-arabinofuranose = H+ + O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-prolyl-[protein] + UDP.,hydroxyproline O-arabinosyltransferase activity,molecular_function
94089,GO:1990586,"A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells.",divisome complex,cellular_component
94090,GO:1990587,"A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ.",FtsQBL complex,cellular_component
94091,GO:1990588,A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL.,FtsBL complex,cellular_component
94092,GO:1990589,"Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.",ATF4-CREB1 transcription factor complex,cellular_component
94093,GO:1990590,Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.,ATF1-ATF4 transcription factor complex,cellular_component
94094,GO:1990591,The directed movement of asparagine into the vacuole across the vacuolar membrane.,asparagine transmembrane import into vacuole,biological_process
94095,GO:1990592,"A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.",protein K69-linked ufmylation,biological_process
94096,GO:1990593,"Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.",nascent polypeptide-associated complex binding,molecular_function
94097,GO:1990594,Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O.,L-altrarate dehydratase activity,molecular_function
94098,GO:1990595,Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.,mast cell secretagogue receptor activity,molecular_function
94099,GO:1990597,A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein).,AIP1-IRE1 complex,cellular_component
94100,GO:1990599,Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks.,3' overhang single-stranded DNA endonuclease activity,molecular_function
94101,GO:1990600,Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity.,single-stranded DNA endodeoxyribonuclease activator activity,molecular_function
94102,GO:1990601,Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.,5' overhang single-stranded DNA endonuclease activity,molecular_function
94103,GO:1990603,The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.,dark adaptation,biological_process
94104,GO:1990604,"A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).",IRE1-TRAF2-ASK1 complex,cellular_component
94105,GO:1990605,Binding to an RNA molecule containing GU repeats.,GU repeat RNA binding,molecular_function
94106,GO:1990606,"Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis.",membrane scission GTPase motor activity,molecular_function
94107,GO:1990608,"A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location.",mitotic spindle pole body localization,biological_process
94108,GO:1990609,Binds to and modulates the activity of glutamate-cysteine ligase.,glutamate-cysteine ligase regulator activity,molecular_function
94109,GO:1990610,Binds to and modulates the activity of acetolactate synthase.,acetolactate synthase regulator activity,molecular_function
94110,GO:1990611,"Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).",regulation of cytoplasmic translational initiation in response to stress,biological_process
94111,GO:1990612,A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.,Sad1-Kms1 LINC complex,cellular_component
94112,GO:1990615,"A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.",Kelch-containing formin regulatory complex,cellular_component
94113,GO:1990616,The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore.,magnesium ion export from mitochondrion,biological_process
94114,GO:1990617,"A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.",CHOP-ATF4 complex,cellular_component
94115,GO:1990620,"A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pre...",ANPR-A receptor complex,cellular_component
94116,GO:1990621,"An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.",ESCRT IV complex,cellular_component
94117,GO:1990622,"A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.",CHOP-ATF3 complex,cellular_component
94118,GO:1990623,"The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively.",Herring body,cellular_component
94119,GO:1990624,"Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.",guanyl nucleotide exchange factor inhibitor activity,molecular_function
94120,GO:1990625,"Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.",negative regulation of cytoplasmic translational initiation in response to stress,biological_process
94121,GO:1990626,The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.,mitochondrial outer membrane fusion,biological_process
94122,GO:1990627,The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.,mitochondrial inner membrane fusion,biological_process
94123,GO:1990629,"A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.",phospholamban complex,cellular_component
94124,GO:1990630,"A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A.",IRE1-RACK1-PP2A complex,cellular_component
94125,GO:1990631,Binding to the protein-tyrosine kinase receptor ErbB-4/HER4.,ErbB-4 class receptor binding,molecular_function
94126,GO:1990633,"A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.",mutator focus,cellular_component
94127,GO:1990634,Binding to protein phosphatase 5.,protein phosphatase 5 binding,molecular_function
94128,GO:1990635,The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma).,proximal dendrite,cellular_component
94129,GO:1990636,A life cycle stage during which the reproductive capacity and fitness of an organism declines.,reproductive senescence,biological_process
94130,GO:1990637,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.",response to prolactin,biological_process
94131,GO:1990638,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.",response to granulocyte colony-stimulating factor,biological_process
94132,GO:1990640,"Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.","inositol-2,4,5-triphosphate 5-phosphatase activity",molecular_function
94133,GO:1990641,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.",response to iron ion starvation,biological_process
94134,GO:1990643,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.",cellular response to granulocyte colony-stimulating factor,biological_process
94135,GO:1990644,The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.,microtubule site clamp,molecular_function
94136,GO:1990646,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.",cellular response to prolactin,biological_process
94137,GO:1990647,"A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP for...",C/EBP complex,cellular_component
94138,GO:1990648,"Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.","inositol-4,5,6-triphosphate 5-phosphatase activity",molecular_function
94139,GO:1990649,"Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.","inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity",molecular_function
94140,GO:1990650,"Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.","inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity",molecular_function
94141,GO:1990651,"Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.","inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity",molecular_function
94142,GO:1990654,"The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.",sebum secreting cell proliferation,biological_process
94143,GO:1990655,"Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.","4 iron, 3 sulfur cluster binding",molecular_function
94144,GO:1990656,The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.,t-SNARE clustering,biological_process
94145,GO:1990657,"A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.",iNOS-S100A8/A9 complex,cellular_component
94146,GO:1990658,A transferase complex which is capable of transferring nitrogenous groups from one component to another.,transnitrosylase complex,cellular_component
94147,GO:1990660,"A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways.",calprotectin complex,cellular_component
94148,GO:1990661,A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).,S100A8 complex,cellular_component
94149,GO:1990662,A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.,S100A9 complex,cellular_component
94150,GO:1990663,Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.,dihydroorotate dehydrogenase (fumarate) activity,molecular_function
94151,GO:1990664,"A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.",Nkx-2.5 complex,cellular_component
94152,GO:1990665,"A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).",AnxA2-p11 complex,cellular_component
94153,GO:1990666,"A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.",PCSK9-LDLR complex,cellular_component
94154,GO:1990667,A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2).,PCSK9-AnxA2 complex,cellular_component
94155,GO:1990668,The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.,vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane,biological_process
94156,GO:1990669,The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.,endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane,biological_process
94157,GO:1990670,The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.,vesicle fusion with Golgi cis cisterna membrane,biological_process
94158,GO:1990671,The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.,vesicle fusion with Golgi medial cisterna membrane,biological_process
94159,GO:1990672,The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.,medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane,biological_process
94160,GO:1990674,"The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.",Golgi cis cisterna membrane,cellular_component
94161,GO:1990675,"The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.",Golgi medial cisterna membrane,cellular_component
94162,GO:1990676,"The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.",Golgi trans cisterna membrane,cellular_component
94163,GO:1990677,A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.,mitochondrial inner membrane assembly complex,cellular_component
94164,GO:1990680,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates.",response to melanocyte-stimulating hormone,biological_process
94165,GO:1990682,"A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.",CSF1-CSF1R complex,cellular_component
94166,GO:1990683,"A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.",DNA double-strand break attachment to nuclear envelope,biological_process
94167,GO:1990684,"A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.",protein-lipid-RNA complex,cellular_component
94168,GO:1990685,"A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.",HDL-containing protein-lipid-RNA complex,cellular_component
94169,GO:1990686,"A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.",LDL-containing protein-lipid-RNA complex,cellular_component
94170,GO:1990687,The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.,endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane,biological_process
94171,GO:1990688,The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.,Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane,biological_process
94172,GO:1990689,The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.,endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane,biological_process
94173,GO:1990690,The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.,Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane,biological_process
94174,GO:1990691,The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.,cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane,biological_process
94175,GO:1990692,The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.,trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane,biological_process
94176,GO:1990696,"A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.",USH2 complex,cellular_component
94177,GO:1990697,"The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.",protein depalmitoleylation,biological_process
94178,GO:1990698,"Catalysis of the transfer of a palmitoleoyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.",palmitoleoyltransferase activity,molecular_function
94179,GO:1990699,"Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.",palmitoleyl hydrolase activity,molecular_function
94180,GO:1990700,"Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.",nucleolar chromatin organization,biological_process
94181,GO:1990705,"The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.",cholangiocyte proliferation,biological_process
94182,GO:1990706,A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).,MAD1 complex,cellular_component
94183,GO:1990708,"The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.",conditioned place preference,biological_process
94184,GO:1990709,"A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.",presynaptic active zone organization,biological_process
94185,GO:1990710,A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.,MutS complex,cellular_component
94186,GO:1990711,Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.,beta-catenin-ICAT complex,cellular_component
94187,GO:1990712,"A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.",HFE-transferrin receptor complex,cellular_component
94188,GO:1990713,A protein complex that negatively regulates apoptotic processes. Complex contains a component which belongs to the family of baculoviral IAP (inhibitor of apoptosis) repeat-containing proteins.,survivin complex,cellular_component
94189,GO:1990714,Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.,hydroxyproline O-galactosyltransferase activity,molecular_function
94190,GO:1990715,Binding to an mRNA molecule coding sequence (CDS).,mRNA CDS binding,molecular_function
94191,GO:1990716,"Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules.",axonemal central apparatus,cellular_component
94192,GO:1990717,"Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.",axonemal central bridge,cellular_component
94193,GO:1990718,"Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.",axonemal central pair projection,cellular_component
94194,GO:1990719,One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.,C1 axonemal microtubule,cellular_component
94195,GO:1990720,One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.,C2 axonemal microtubule,cellular_component
94196,GO:1990722,"A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.",DAPK1-calmodulin complex,cellular_component
94197,GO:1990723,Cytoplasm situated in close proximity to a nuclear pore complex.,cytoplasmic periphery of the nuclear pore complex,cellular_component
94198,GO:1990724,A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.,galectin complex,cellular_component
94199,GO:1990725,"Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.",cord factor receptor activity,molecular_function
94200,GO:1990726,"A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.",Lsm1-7-Pat1 complex,cellular_component
94201,GO:1990728,"A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex.",mitotic spindle assembly checkpoint MAD1-MAD2 complex,cellular_component
94202,GO:1990730,"A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.",VCP-NSFL1C complex,cellular_component
94203,GO:1990732,A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.,pyrenoid,cellular_component
94204,GO:1990733,"A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.",titin-telethonin complex,cellular_component
94205,GO:1990734,Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.,astral microtubule anchoring at mitotic spindle pole body,biological_process
94206,GO:1990735,"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.",gamma-tubulin complex localization to mitotic spindle pole body,biological_process
94207,GO:1990736,Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.,regulation of vascular associated smooth muscle cell membrane depolarization,biological_process
94208,GO:1990737,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.",response to manganese-induced endoplasmic reticulum stress,biological_process
94209,GO:1990738,Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.,pseudouridine 5'-phosphatase activity,molecular_function
94210,GO:1990739,"The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.",granulosa cell proliferation,biological_process
94211,GO:1990742,An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.,microvesicle,cellular_component
94212,GO:1990743,A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.,protein sialylation,biological_process
94213,GO:1990745,A quatrefoil tethering complex required for endocytic recycling.,EARP complex,cellular_component
94214,GO:1990747,The regulated release of trypsinogen from the cells of the exocrine pancreas.,pancreatic trypsinogen secretion,biological_process
94215,GO:1990748,Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.,cellular detoxification,biological_process
94216,GO:1990749,Increases the activity of the enzyme polynucleotide adenylyltransferase.,polynucleotide adenylyltransferase activator activity,molecular_function
94217,GO:1990751,The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,Schwann cell chemotaxis,biological_process
94218,GO:1990752,"Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.",microtubule end,cellular_component
94219,GO:1990753,The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.,equatorial cell cortex,cellular_component
94220,GO:1990755,The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.,mitotic spindle microtubule depolymerization,biological_process
94221,GO:1990756,The binding activity of a molecule that brings together a ubiquitin-like ligase (including ubiquitin ligase and UFM1 ligase) and its substrate. Usually mediated by F-box BTB/POZ domain proteins.,ubiquitin-like ligase-substrate adaptor activity,molecular_function
94222,GO:1990757,Binds to and increases the activity of a ubiquitin ligase.,ubiquitin ligase activator activity,molecular_function
94223,GO:1990758,"The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.",mitotic sister chromatid biorientation,biological_process
94224,GO:1990760,Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.,osmolarity-sensing monoatomic cation channel activity,molecular_function
94225,GO:1990761,A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.,growth cone lamellipodium,cellular_component
94226,GO:1990762,"The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.",cytoplasmic alanyl-tRNA aminoacylation,biological_process
94227,GO:1990763,"Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.",arrestin family protein binding,molecular_function
94228,GO:1990764,The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.,myofibroblast contraction,biological_process
94229,GO:1990765,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.",colon smooth muscle contraction,biological_process
94230,GO:1990767,The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.,prostaglandin receptor internalization,biological_process
94231,GO:1990768,"The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.",gastric mucosal blood circulation,biological_process
94232,GO:1990769,The portion of an axon or dendrite that is close to the neuronal cell body.,proximal neuron projection,cellular_component
94233,GO:1990770,"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.",small intestine smooth muscle contraction,biological_process
94234,GO:1990771,The clathrin-mediated endocytosis of an extracellular exosome.,clathrin-dependent extracellular exosome endocytosis,biological_process
94235,GO:1990772,"The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.",substance P secretion,biological_process
94236,GO:1990773,"The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.",matrix metallopeptidase secretion,biological_process
94237,GO:1990775,"The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.",endothelin production,biological_process
94238,GO:1990776,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.",response to angiotensin,biological_process
94239,GO:1990777,A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.,lipoprotein particle,cellular_component
94240,GO:1990778,"A process in which a protein is transported to, or maintained in, the cell periphery.",protein localization to cell periphery,biological_process
94241,GO:1990779,A transmembrane signaling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.,glycoprotein Ib-IX-V complex,cellular_component
94242,GO:1990780,"The leaflet of the plasma membrane in the dendritic spine region that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.",cytoplasmic side of dendritic spine plasma membrane,cellular_component
94243,GO:1990781,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.",response to immobilization stress combined with electrical stimulus,biological_process
94244,GO:1990782,Binding to protein tyrosine kinase.,protein tyrosine kinase binding,molecular_function
94245,GO:1990783,"Cytoplasm situated near, or occurring around, a phagosome.",periphagosomal region of cytoplasm,cellular_component
94246,GO:1990784,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.",response to dsDNA,biological_process
94247,GO:1990785,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.",response to water-immersion restraint stress,biological_process
94248,GO:1990786,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.",cellular response to dsDNA,biological_process
94249,GO:1990788,A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.,GLI-SUFU complex,cellular_component
94250,GO:1990789,"The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population.",thyroid gland epithelial cell proliferation,biological_process
94251,GO:1990790,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.",response to glial cell derived neurotrophic factor,biological_process
94252,GO:1990791,"The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.",dorsal root ganglion development,biological_process
94253,GO:1990792,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.",cellular response to glial cell derived neurotrophic factor,biological_process
94254,GO:1990793,"The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.","substance P secretion, neurotransmission",biological_process
94255,GO:1990794,The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.,basolateral part of cell,cellular_component
94256,GO:1990795,A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.,rod bipolar cell terminal bouton,cellular_component
94257,GO:1990796,A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.,photoreceptor cell terminal bouton,cellular_component
94258,GO:1990798,The regrowth of a destroyed pancreas.,pancreas regeneration,biological_process
94259,GO:1990799,The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from L-cysteine to position C2 by several steps.,mitochondrial tRNA wobble position uridine thiolation,biological_process
94260,GO:1990805,A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.,central cylinder,cellular_component
94261,GO:1990806,"The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.",ligand-gated ion channel signaling pathway,biological_process
94262,GO:1990808,"Binding to an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins.",F-bar domain binding,molecular_function
94263,GO:1990809,"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.",endoplasmic reticulum tubular network membrane organization,biological_process
94264,GO:1990810,Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.,microtubule anchoring at mitotic spindle pole body,biological_process
94265,GO:1990811,"A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.",MWP complex,cellular_component
94266,GO:1990812,"A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.",growth cone filopodium,cellular_component
94267,GO:1990813,The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I after cohesin is cleaved by separase along the arm regions.,meiotic centromeric cohesion protection in anaphase I,biological_process
94268,GO:1990814,An activity that facilitates the formation of a complementary double-stranded DNA molecule.,DNA/DNA annealing activity,molecular_function
94269,GO:1990816,"A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.",vacuole-mitochondrion membrane contact site,cellular_component
94270,GO:1990817,"Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.",poly(A) RNA polymerase activity,molecular_function
94271,GO:1990818,"The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.",L-arginine transmembrane export from vacuole,biological_process
94272,GO:1990819,A focus at the mating projection tip where the cell wall is degraded during cytogamy. Actin filaments form an aster-like structure from this location.,mating projection actin fusion focus,cellular_component
94273,GO:1990820,A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.,response to mitotic DNA integrity checkpoint signaling,biological_process
94274,GO:1990822,The directed movement of basic amino acids from one side of a membrane to the other.,basic amino acid transmembrane transport,biological_process
94275,GO:1990823,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.",response to leukemia inhibitory factor,biological_process
94276,GO:1990825,Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.,sequence-specific mRNA binding,molecular_function
94277,GO:1990826,Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.,nucleoplasmic periphery of the nuclear pore complex,cellular_component
94278,GO:1990827,"Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).",deaminase binding,molecular_function
94279,GO:1990828,"The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.",hepatocyte dedifferentiation,biological_process
94280,GO:1990829,"Binding to C-rich, single-stranded DNA.",C-rich single-stranded DNA binding,molecular_function
94281,GO:1990830,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.",cellular response to leukemia inhibitory factor,biological_process
94282,GO:1990831,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.",cellular response to carcinoembryonic antigen,biological_process
94283,GO:1990832,The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.,slow axonal transport,biological_process
94284,GO:1990833,"Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP.",clathrin-uncoating ATPase activity,molecular_function
94285,GO:1990834,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.",response to odorant,biological_process
94286,GO:1990836,A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.,lysosomal matrix,cellular_component
94287,GO:1990837,"Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.",sequence-specific double-stranded DNA binding,molecular_function
94288,GO:1990838,"Catalysis of the reaction: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine.","poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends",molecular_function
94289,GO:1990839,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).",response to endothelin,biological_process
94290,GO:1990840,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.",response to lectin,biological_process
94291,GO:1990841,Binding to a section of chromatin that is associated with gene promoter sequences of DNA.,promoter-specific chromatin binding,molecular_function
94292,GO:1990845,"The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.",adaptive thermogenesis,biological_process
94293,GO:1990846,"Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.",ribonucleoside-diphosphate reductase inhibitor activity,molecular_function
94294,GO:1990849,"Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.",vacuolar localization,biological_process
94295,GO:1990850,A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.,H-gal-GP complex,cellular_component
94296,GO:1990851,"A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.",Wnt-Frizzled-LRP5/6 complex,cellular_component
94297,GO:1990852,"The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.",protein transport along microtubule to spindle pole body,biological_process
94298,GO:1990856,Binding to methionine-initiator methionine tRNA.,methionyl-initiator methionine tRNA binding,molecular_function
94299,GO:1990858,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.",cellular response to lectin,biological_process
94300,GO:1990859,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).",cellular response to endothelin,biological_process
94301,GO:1990860,A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.,Pho85-Pho80 CDK-cyclin complex,cellular_component
94302,GO:1990861,"A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.",Ubp3-Bre5 deubiquitination complex,cellular_component
94303,GO:1990862,"A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.",nuclear membrane complex Bqt3-Bqt4,cellular_component
94304,GO:1990863,"The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).",acinar cell proliferation,biological_process
94305,GO:1990864,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.",response to growth hormone-releasing hormone,biological_process
94306,GO:1990867,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.",response to gastrin,biological_process
94307,GO:1990868,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.",response to chemokine,biological_process
94308,GO:1990869,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.",cellular response to chemokine,biological_process
94309,GO:1990871,"A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.",Vma12-Vma22 assembly complex,cellular_component
94310,GO:1990874,"The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.",vascular associated smooth muscle cell proliferation,biological_process
94311,GO:1990875,The side of the nuclear pore complex (NPC) that faces the nucleoplasm.,nucleoplasmic side of nuclear pore,cellular_component
94312,GO:1990876,The side of the nuclear pore complex (NPC) that faces the cytoplasm.,cytoplasmic side of nuclear pore,cellular_component
94313,GO:1990877,"A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.",FNIP-folliculin RagC/D GAP,cellular_component
94314,GO:1990878,"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.",cellular response to gastrin,biological_process
94315,GO:1990879,A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.,CST complex,cellular_component
94316,GO:1990880,Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.,cellular detoxification of copper ion,biological_process
94317,GO:1990882,"The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.",rRNA acetylation,biological_process
94318,GO:1990883,Catalysis of the reaction: a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H+.,18S rRNA cytidine N-acetyltransferase activity,molecular_function
94319,GO:1990884,The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.,RNA acetylation,biological_process
94320,GO:1990888,Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.,2-polyprenyl-6-hydroxyphenol O-methyltransferase activity,molecular_function
94321,GO:1990889,A histone reader that recognizes a histone H4 trimethylated at lysine 20.,histone H4K20me3 reader activity,molecular_function
94322,GO:1990890,Binding to a netrin receptor.,netrin receptor binding,molecular_function
94323,GO:1990891,The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.,mitotic sister chromatid arm separation,biological_process
94324,GO:1990892,The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.,mitotic chromosome arm condensation,biological_process
94325,GO:1990893,The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.,mitotic chromosome centromere condensation,biological_process
94326,GO:1990895,"Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.",regulation of protein localization to cell cortex of cell tip,biological_process
94327,GO:1990896,"A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.",protein localization to cell cortex of cell tip,biological_process
94328,GO:1990900,"A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.",ciliary pocket collar,cellular_component
94329,GO:1990901,The cell pole distal from the most recent cell division.,old cell pole,cellular_component
94330,GO:1990902,The cell pole proximal to the most recent cell division.,new cell pole,cellular_component
94331,GO:1990904,A macromolecular complex that contains both RNA and protein molecules.,ribonucleoprotein complex,cellular_component
94332,GO:1990905,"A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).",dinoflagellate peduncle,cellular_component
94333,GO:1990906,A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.,accessory outer segment,cellular_component
94334,GO:1990907,A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.,beta-catenin-TCF complex,cellular_component
94335,GO:1990909,"A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.",Wnt signalosome,cellular_component
94336,GO:1990910,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).",response to hypobaric hypoxia,biological_process
94337,GO:1990911,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.",response to psychosocial stress,biological_process
94338,GO:1990913,The plasma membrane that is part of the head section of a sperm cell.,sperm head plasma membrane,cellular_component
94339,GO:1990915,The action of a molecule that contributes to the structural integrity of an ascospore wall.,structural constituent of ascospore wall,molecular_function
94340,GO:1990916,"The outermost layers of the spore wall, as described in Schizosaccharomyces pombe.",Isp3 layer of spore wall,cellular_component
94341,GO:1990917,The cytoplasm of an ovum.,ooplasm,cellular_component
94342,GO:1990918,The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.,double-strand break repair involved in meiotic recombination,biological_process
94343,GO:1990919,"The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome.",proteasome-nuclear membrane anchor activity,molecular_function
94344,GO:1990922,"The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.",hepatic stellate cell proliferation,biological_process
94345,GO:1990923,"A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs.",PET complex,cellular_component
94346,GO:1990926,"The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds.",short-term synaptic potentiation,biological_process
94347,GO:1990927,"The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.",calcium ion regulated lysosome exocytosis,biological_process
94348,GO:1990928,"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.",response to amino acid starvation,biological_process
94349,GO:1990929,"Catalysis of the reaction: a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O = 6-sulfo-alpha-D-quinovose + a 1,2-diacyl-sn-glycerol.",sulfoquinovosidase activity,molecular_function
94350,GO:1990930,"Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.",mRNA N1-methyladenosine dioxygenase activity,molecular_function
94351,GO:1990931,"Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.",mRNA N6-methyladenosine dioxygenase activity,molecular_function
94352,GO:1990932,"Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.",5.8S rRNA binding,molecular_function
94353,GO:1990933,A process in which the microtubule cytoskeleton is attached to the nuclear envelope.,microtubule cytoskeleton attachment to nuclear envelope,biological_process
94354,GO:1990934,"A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.",nucleolus-like body,cellular_component
94355,GO:1990935,Binding to a protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA.,splicing factor binding,molecular_function
94356,GO:1990936,"The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.",vascular associated smooth muscle cell dedifferentiation,biological_process
94357,GO:1990941,"Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation.",mitotic spindle kinetochore microtubule,cellular_component
94358,GO:1990942,A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase...,mitotic metaphase chromosome recapture,biological_process
94359,GO:1990946,The cell cycle process in which a cell progresses from meiosis I to meiosis II.,meiosis I/meiosis II transition,biological_process
94360,GO:1990947,"Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half.",exit from meiosis,biological_process
94361,GO:1990948,"Binds to and stops, prevents or reduces the activity of a ubiquitin ligase.",ubiquitin ligase inhibitor activity,molecular_function
94362,GO:1990949,The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.,metaphase/anaphase transition of meiosis I,biological_process
94363,GO:1990950,The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II.,metaphase/anaphase transition of meiosis II,biological_process
94364,GO:1990953,"The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.",intramanchette transport,biological_process
94365,GO:1990955,"Binding to G-rich, single-stranded DNA.",G-rich single-stranded DNA binding,molecular_function
94366,GO:1990956,The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).,fibroblast chemotaxis,biological_process
94367,GO:1990957,"A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.",NPHP complex,cellular_component
94368,GO:1990959,The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.,eosinophil homeostasis,biological_process
94369,GO:1990960,The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.,basophil homeostasis,biological_process
94370,GO:1990961,A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.,xenobiotic detoxification by transmembrane export across the plasma membrane,biological_process
94371,GO:1990962,The directed movement of a xenobiotic through the blood-brain barrier.,xenobiotic transport across blood-brain barrier,biological_process
94372,GO:1990963,"Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.",establishment of blood-retinal barrier,biological_process
94373,GO:1990964,"A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat.",actin cytoskeleton-regulatory complex,cellular_component
94374,GO:1990965,Catalysis of the reaction: cytosylglucuronic acid + H+ = cytosylarabinopyranose + CO2.,cytosylglucuronate decarboxylase activity,molecular_function
94375,GO:1990966,The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.,ATP generation from poly-ADP-D-ribose,biological_process
94376,GO:1990968,"A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.",modulation by host of RNA binding by virus,biological_process
94377,GO:1990970,"Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.",trans-activation response element binding,molecular_function
94378,GO:1990971,The elastin microfibril interface located protein (EMILINs) are glycoprotein complexes of the C1q/TNF superfamily characterized by an N-terminal EMI domain. EMILIN homotrimers assemble to form supramolecular EMILIN structures.,EMILIN complex,cellular_component
94379,GO:1990972,Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.,multimerin complex,cellular_component
94380,GO:1990973,"A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).",transmembrane actin-associated (TAN) line,cellular_component
94381,GO:1990974,The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.,actin-dependent nuclear migration,biological_process
94382,GO:1990976,"The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.",protein transport along microtubule to mitotic spindle pole body,biological_process
94383,GO:1990983,A process in which translation initiation is regulated by post-translation modifications of a tRNA molecule.,regulation of translational initiation by tRNA modification,biological_process
94384,GO:1990984,Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule.,tRNA demethylase activity,molecular_function
94385,GO:1990986,The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).,DNA recombinase disassembly,biological_process
94386,GO:2000001,"Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.",regulation of DNA damage checkpoint,biological_process
94387,GO:2000002,"Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.",negative regulation of DNA damage checkpoint,biological_process
94388,GO:2000003,"Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.",positive regulation of DNA damage checkpoint,biological_process
94389,GO:2000004,"Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.",regulation of metanephric S-shaped body morphogenesis,biological_process
94390,GO:2000005,"Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.",negative regulation of metanephric S-shaped body morphogenesis,biological_process
94391,GO:2000006,"Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.",regulation of metanephric comma-shaped body morphogenesis,biological_process
94392,GO:2000007,"Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.",negative regulation of metanephric comma-shaped body morphogenesis,biological_process
94393,GO:2000008,"Any process that modulates the frequency, rate or extent of protein localization to the cell surface.",regulation of protein localization to cell surface,biological_process
94394,GO:2000009,"Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.",negative regulation of protein localization to cell surface,biological_process
94395,GO:2000010,"Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.",positive regulation of protein localization to cell surface,biological_process
94396,GO:2000011,"Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.",regulation of adaxial/abaxial pattern formation,biological_process
94397,GO:2000012,"Any process that modulates the frequency, rate or extent of auxin polar transport.",regulation of auxin polar transport,biological_process
94398,GO:2000014,"Any process that modulates the frequency, rate or extent of endosperm development.",regulation of endosperm development,biological_process
94399,GO:2000015,"Any process that modulates the frequency, rate or extent of determination of dorsal identity.",regulation of determination of dorsal identity,biological_process
94400,GO:2000016,"Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.",negative regulation of determination of dorsal identity,biological_process
94401,GO:2000017,"Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.",positive regulation of determination of dorsal identity,biological_process
94402,GO:2000018,"Any process that modulates the frequency, rate or extent of male gonad development.",regulation of male gonad development,biological_process
94403,GO:2000019,"Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.",negative regulation of male gonad development,biological_process
94404,GO:2000020,"Any process that activates or increases the frequency, rate or extent of male gonad development.",positive regulation of male gonad development,biological_process
94405,GO:2000022,"Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.",regulation of jasmonic acid mediated signaling pathway,biological_process
94406,GO:2000023,"Any process that modulates the frequency, rate or extent of lateral root development.",regulation of lateral root development,biological_process
94407,GO:2000024,"Any process that modulates the frequency, rate or extent of leaf development.",regulation of leaf development,biological_process
94408,GO:2000025,"Any process that modulates the frequency, rate or extent of leaf formation.",regulation of leaf formation,biological_process
94409,GO:2000026,"Any process that modulates the frequency, rate or extent of multicellular organismal development.",regulation of multicellular organismal development,biological_process
94410,GO:2000027,"Any process that modulates the frequency, rate or extent of animal organ morphogenesis.",regulation of animal organ morphogenesis,biological_process
94411,GO:2000028,"Any process that modulates the frequency, rate or extent of photoperiodism, flowering.","regulation of photoperiodism, flowering",biological_process
94412,GO:2000029,"Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.",regulation of proanthocyanidin biosynthetic process,biological_process
94413,GO:2000030,"Any process that modulates the frequency, rate or extent of response to red or far red light.",regulation of response to red or far red light,biological_process
94414,GO:2000031,"Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.",regulation of salicylic acid mediated signaling pathway,biological_process
94415,GO:2000032,"Any process that modulates the frequency, rate or extent of secondary shoot formation.",regulation of secondary shoot formation,biological_process
94416,GO:2000033,"Any process that modulates the frequency, rate or extent of seed dormancy process.",regulation of seed dormancy process,biological_process
94417,GO:2000034,"Any process that modulates the frequency, rate or extent of seed maturation.",regulation of seed maturation,biological_process
94418,GO:2000035,"Any process that modulates the frequency, rate or extent of stem cell division.",regulation of stem cell division,biological_process
94419,GO:2000036,"Any process that modulates the frequency, rate or extent of stem cell population maintenance.",regulation of stem cell population maintenance,biological_process
94420,GO:2000037,"Any process that modulates the frequency, rate or extent of stomatal complex patterning.",regulation of stomatal complex patterning,biological_process
94421,GO:2000038,"Any process that modulates the frequency, rate or extent of stomatal complex development.",regulation of stomatal complex development,biological_process
94422,GO:2000039,"Any process that modulates the frequency, rate or extent of trichome morphogenesis.",regulation of trichome morphogenesis,biological_process
94423,GO:2000042,"Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.",negative regulation of double-strand break repair via homologous recombination,biological_process
94424,GO:2000043,"Any process that modulates the frequency, rate or extent of cardiac cell fate specification.",regulation of cardiac cell fate specification,biological_process
94425,GO:2000044,"Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.",negative regulation of cardiac cell fate specification,biological_process
94426,GO:2000045,Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.,regulation of G1/S transition of mitotic cell cycle,biological_process
94427,GO:2000047,"Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.",regulation of cell-cell adhesion mediated by cadherin,biological_process
94428,GO:2000048,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.",negative regulation of cell-cell adhesion mediated by cadherin,biological_process
94429,GO:2000049,"Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin.",positive regulation of cell-cell adhesion mediated by cadherin,biological_process
94430,GO:2000050,"Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway.",regulation of non-canonical Wnt signaling pathway,biological_process
94431,GO:2000051,"Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway.",negative regulation of non-canonical Wnt signaling pathway,biological_process
94432,GO:2000052,"Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.",positive regulation of non-canonical Wnt signaling pathway,biological_process
94433,GO:2000058,"Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process.",regulation of ubiquitin-dependent protein catabolic process,biological_process
94434,GO:2000059,"Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.",negative regulation of ubiquitin-dependent protein catabolic process,biological_process
94435,GO:2000060,"Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process.",positive regulation of ubiquitin-dependent protein catabolic process,biological_process
94436,GO:2000061,"Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.",regulation of ureter smooth muscle cell differentiation,biological_process
94437,GO:2000062,"Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.",negative regulation of ureter smooth muscle cell differentiation,biological_process
94438,GO:2000063,"Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.",positive regulation of ureter smooth muscle cell differentiation,biological_process
94439,GO:2000064,"Any process that modulates the frequency, rate or extent of cortisol biosynthetic process.",regulation of cortisol biosynthetic process,biological_process
94440,GO:2000065,"Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.",negative regulation of cortisol biosynthetic process,biological_process
94441,GO:2000066,"Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.",positive regulation of cortisol biosynthetic process,biological_process
94442,GO:2000067,"Any process that modulates the frequency, rate or extent of root morphogenesis.",regulation of root morphogenesis,biological_process
94443,GO:2000068,"Any process that modulates the frequency, rate or extent of defense response to insect.",regulation of defense response to insect,biological_process
94444,GO:2000069,"Any process that modulates the frequency, rate or extent of post-embryonic root development.",regulation of post-embryonic root development,biological_process
94445,GO:2000070,"Any process that modulates the frequency, rate or extent of response to water deprivation.",regulation of response to water deprivation,biological_process
94446,GO:2000071,"Any process that modulates the frequency, rate or extent of defense response by callose deposition.",regulation of defense response by callose deposition,biological_process
94447,GO:2000073,"Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.","regulation of cytokinesis, site selection",biological_process
94448,GO:2000074,"Any process that modulates the frequency, rate or extent of pancreatic B cell development.",regulation of type B pancreatic cell development,biological_process
94449,GO:2000075,"Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.","negative regulation of cytokinesis, site selection",biological_process
94450,GO:2000076,"Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.","positive regulation of cytokinesis, site selection",biological_process
94451,GO:2000077,"Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.",negative regulation of type B pancreatic cell development,biological_process
94452,GO:2000078,"Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.",positive regulation of type B pancreatic cell development,biological_process
94453,GO:2000082,"Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.",regulation of L-ascorbic acid biosynthetic process,biological_process
94454,GO:2000083,"Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.",negative regulation of L-ascorbic acid biosynthetic process,biological_process
94455,GO:2000087,"Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.",regulation of mesonephric glomerulus development,biological_process
94456,GO:2000088,"Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.",negative regulation of mesonephric glomerulus development,biological_process
94457,GO:2000089,"Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.",positive regulation of mesonephric glomerulus development,biological_process
94458,GO:2000090,"Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.",regulation of mesonephric glomerular mesangial cell proliferation,biological_process
94459,GO:2000091,"Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.",negative regulation of mesonephric glomerular mesangial cell proliferation,biological_process
94460,GO:2000092,"Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.",positive regulation of mesonephric glomerular mesangial cell proliferation,biological_process
94461,GO:2000093,"Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.",regulation of mesonephric nephron tubule epithelial cell differentiation,biological_process
94462,GO:2000094,"Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.",negative regulation of mesonephric nephron tubule epithelial cell differentiation,biological_process
94463,GO:2000095,"Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.","regulation of Wnt signaling pathway, planar cell polarity pathway",biological_process
94464,GO:2000096,"Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.","positive regulation of Wnt signaling pathway, planar cell polarity pathway",biological_process
94465,GO:2000097,"Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.",regulation of smooth muscle cell-matrix adhesion,biological_process
94466,GO:2000098,"Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.",negative regulation of smooth muscle cell-matrix adhesion,biological_process
94467,GO:2000099,"Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity.",regulation of establishment or maintenance of bipolar cell polarity,biological_process
94468,GO:2000100,"Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.",regulation of establishment or maintenance of bipolar cell polarity regulating cell shape,biological_process
94469,GO:2000101,"Any process that modulates the frequency, rate or extent of mammary stem cell proliferation.",regulation of mammary stem cell proliferation,biological_process
94470,GO:2000102,"Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation.",negative regulation of mammary stem cell proliferation,biological_process
94471,GO:2000103,"Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation.",positive regulation of mammary stem cell proliferation,biological_process
94472,GO:2000104,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.",negative regulation of DNA-templated DNA replication,biological_process
94473,GO:2000105,"Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.",positive regulation of DNA-templated DNA replication,biological_process
94474,GO:2000106,"Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.",regulation of leukocyte apoptotic process,biological_process
94475,GO:2000107,"Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.",negative regulation of leukocyte apoptotic process,biological_process
94476,GO:2000108,"Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.",positive regulation of leukocyte apoptotic process,biological_process
94477,GO:2000109,"Any process that modulates the frequency, rate or extent of macrophage apoptotic process.",regulation of macrophage apoptotic process,biological_process
94478,GO:2000110,"Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.",negative regulation of macrophage apoptotic process,biological_process
94479,GO:2000111,"Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.",positive regulation of macrophage apoptotic process,biological_process
94480,GO:2000114,"Any process that modulates the frequency, rate or extent of establishment of cell polarity.",regulation of establishment of cell polarity,biological_process
94481,GO:2000115,"Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.",regulation of maintenance of bipolar cell polarity regulating cell shape,biological_process
94482,GO:2000118,"Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport.",regulation of sodium-dependent phosphate transport,biological_process
94483,GO:2000119,"Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.",negative regulation of sodium-dependent phosphate transport,biological_process
94484,GO:2000120,"Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport.",positive regulation of sodium-dependent phosphate transport,biological_process
94485,GO:2000121,"Any process that modulates the frequency, rate or extent of removal of superoxide radicals.",regulation of removal of superoxide radicals,biological_process
94486,GO:2000122,"Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.",negative regulation of stomatal complex development,biological_process
94487,GO:2000123,"Any process that activates or increases the frequency, rate or extent of stomatal complex development.",positive regulation of stomatal complex development,biological_process
94488,GO:2000124,"Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.",regulation of endocannabinoid signaling pathway,biological_process
94489,GO:2000125,"Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.",regulation of octopamine or tyramine signaling pathway,biological_process
94490,GO:2000126,"Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway.",negative regulation of octopamine or tyramine signaling pathway,biological_process
94491,GO:2000127,"Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.",positive regulation of octopamine or tyramine signaling pathway,biological_process
94492,GO:2000128,"Any process that modulates the frequency, rate or extent of octopamine signaling pathway.",regulation of octopamine signaling pathway,biological_process
94493,GO:2000129,"Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.",negative regulation of octopamine signaling pathway,biological_process
94494,GO:2000130,"Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.",positive regulation of octopamine signaling pathway,biological_process
94495,GO:2000131,"Any process that modulates the frequency, rate or extent of tyramine signaling pathway.",regulation of tyramine signaling pathway,biological_process
94496,GO:2000132,"Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.",negative regulation of tyramine signaling pathway,biological_process
94497,GO:2000133,"Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.",positive regulation of tyramine signaling pathway,biological_process
94498,GO:2000134,Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.,negative regulation of G1/S transition of mitotic cell cycle,biological_process
94499,GO:2000136,"Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.",regulation of cell proliferation involved in heart morphogenesis,biological_process
94500,GO:2000137,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.",negative regulation of cell proliferation involved in heart morphogenesis,biological_process
94501,GO:2000138,"Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.",positive regulation of cell proliferation involved in heart morphogenesis,biological_process
94502,GO:2000142,"Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.",regulation of DNA-templated transcription initiation,biological_process
94503,GO:2000143,"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.",negative regulation of DNA-templated transcription initiation,biological_process
94504,GO:2000144,"Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.",positive regulation of DNA-templated transcription initiation,biological_process
94505,GO:2000145,"Any process that modulates the frequency, rate or extent of cell motility.",regulation of cell motility,biological_process
94506,GO:2000146,"Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.",negative regulation of cell motility,biological_process
94507,GO:2000147,"Any process that activates or increases the frequency, rate or extent of cell motility.",positive regulation of cell motility,biological_process
94508,GO:2000155,"Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.",positive regulation of cilium-dependent cell motility,biological_process
94509,GO:2000156,"Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.","regulation of retrograde vesicle-mediated transport, Golgi to ER",biological_process
94510,GO:2000158,"Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.",positive regulation of ubiquitin-specific protease activity,biological_process
94511,GO:2000169,"Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.",regulation of peptidyl-cysteine S-nitrosylation,biological_process
94512,GO:2000170,"Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.",positive regulation of peptidyl-cysteine S-nitrosylation,biological_process
94513,GO:2000171,"Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.",negative regulation of dendrite development,biological_process
94514,GO:2000172,"Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.",regulation of branching morphogenesis of a nerve,biological_process
94515,GO:2000173,"Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.",negative regulation of branching morphogenesis of a nerve,biological_process
94516,GO:2000174,"Any process that modulates the frequency, rate or extent of pro-T cell differentiation.",regulation of pro-T cell differentiation,biological_process
94517,GO:2000175,"Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.",negative regulation of pro-T cell differentiation,biological_process
94518,GO:2000176,"Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.",positive regulation of pro-T cell differentiation,biological_process
94519,GO:2000177,"Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.",regulation of neural precursor cell proliferation,biological_process
94520,GO:2000178,"Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.",negative regulation of neural precursor cell proliferation,biological_process
94521,GO:2000179,"Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.",positive regulation of neural precursor cell proliferation,biological_process
94522,GO:2000180,"Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.",negative regulation of androgen biosynthetic process,biological_process
94523,GO:2000181,"Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.",negative regulation of blood vessel morphogenesis,biological_process
94524,GO:2000182,"Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.",regulation of progesterone biosynthetic process,biological_process
94525,GO:2000183,"Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.",negative regulation of progesterone biosynthetic process,biological_process
94526,GO:2000184,"Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.",positive regulation of progesterone biosynthetic process,biological_process
94527,GO:2000185,"Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.",regulation of phosphate transmembrane transport,biological_process
94528,GO:2000186,"Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.",negative regulation of phosphate transmembrane transport,biological_process
94529,GO:2000187,"Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.",positive regulation of phosphate transmembrane transport,biological_process
94530,GO:2000191,"Any process that modulates the frequency, rate or extent of fatty acid transport.",regulation of fatty acid transport,biological_process
94531,GO:2000192,"Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.",negative regulation of fatty acid transport,biological_process
94532,GO:2000193,"Any process that activates or increases the frequency, rate or extent of fatty acid transport.",positive regulation of fatty acid transport,biological_process
94533,GO:2000194,"Any process that modulates the frequency, rate or extent of female gonad development.",regulation of female gonad development,biological_process
94534,GO:2000195,"Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.",negative regulation of female gonad development,biological_process
94535,GO:2000196,"Any process that activates or increases the frequency, rate or extent of female gonad development.",positive regulation of female gonad development,biological_process
94536,GO:2000197,"Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization.",regulation of ribonucleoprotein complex localization,biological_process
94537,GO:2000198,"Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.",negative regulation of ribonucleoprotein complex localization,biological_process
94538,GO:2000199,"Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization.",positive regulation of ribonucleoprotein complex localization,biological_process
94539,GO:2000200,"Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.",regulation of ribosomal subunit export from nucleus,biological_process
94540,GO:2000201,"Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus.",negative regulation of ribosomal subunit export from nucleus,biological_process
94541,GO:2000202,"Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus.",positive regulation of ribosomal subunit export from nucleus,biological_process
94542,GO:2000203,"Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus.",regulation of ribosomal large subunit export from nucleus,biological_process
94543,GO:2000204,"Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.",negative regulation of ribosomal large subunit export from nucleus,biological_process
94544,GO:2000205,"Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.",positive regulation of ribosomal large subunit export from nucleus,biological_process
94545,GO:2000206,"Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.",regulation of ribosomal small subunit export from nucleus,biological_process
94546,GO:2000207,"Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.",negative regulation of ribosomal small subunit export from nucleus,biological_process
94547,GO:2000208,"Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.",positive regulation of ribosomal small subunit export from nucleus,biological_process
94548,GO:2000209,"Any process that modulates the frequency, rate or extent of anoikis.",regulation of anoikis,biological_process
94549,GO:2000210,"Any process that activates or increases the frequency, rate or extent of anoikis.",positive regulation of anoikis,biological_process
94550,GO:2000217,"Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.",regulation of invasive growth in response to glucose limitation,biological_process
94551,GO:2000218,"Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.",negative regulation of invasive growth in response to glucose limitation,biological_process
94552,GO:2000219,"Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.",positive regulation of invasive growth in response to glucose limitation,biological_process
94553,GO:2000220,"Any process that modulates the frequency, rate or extent of pseudohyphal growth.",regulation of pseudohyphal growth,biological_process
94554,GO:2000221,"Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.",negative regulation of pseudohyphal growth,biological_process
94555,GO:2000222,"Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.",positive regulation of pseudohyphal growth,biological_process
94556,GO:2000224,"Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.",regulation of testosterone biosynthetic process,biological_process
94557,GO:2000225,"Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.",negative regulation of testosterone biosynthetic process,biological_process
94558,GO:2000226,"Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.",regulation of pancreatic A cell differentiation,biological_process
94559,GO:2000227,"Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.",negative regulation of pancreatic A cell differentiation,biological_process
94560,GO:2000228,"Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.",positive regulation of pancreatic A cell differentiation,biological_process
94561,GO:2000229,"Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.",regulation of pancreatic stellate cell proliferation,biological_process
94562,GO:2000230,"Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.",negative regulation of pancreatic stellate cell proliferation,biological_process
94563,GO:2000231,"Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.",positive regulation of pancreatic stellate cell proliferation,biological_process
94564,GO:2000232,"Any process that modulates the frequency, rate or extent of rRNA processing.",regulation of rRNA processing,biological_process
94565,GO:2000233,"Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.",negative regulation of rRNA processing,biological_process
94566,GO:2000234,"Any process that activates or increases the frequency, rate or extent of rRNA processing.",positive regulation of rRNA processing,biological_process
94567,GO:2000235,"Any process that modulates the frequency, rate or extent of tRNA processing.",regulation of tRNA processing,biological_process
94568,GO:2000236,"Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.",negative regulation of tRNA processing,biological_process
94569,GO:2000237,"Any process that activates or increases the frequency, rate or extent of tRNA processing.",positive regulation of tRNA processing,biological_process
94570,GO:2000238,"Any process that modulates the frequency, rate or extent of tRNA export from nucleus.",regulation of tRNA export from nucleus,biological_process
94571,GO:2000239,"Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.",negative regulation of tRNA export from nucleus,biological_process
94572,GO:2000240,"Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus.",positive regulation of tRNA export from nucleus,biological_process
94573,GO:2000241,"Any process that modulates the frequency, rate or extent of reproductive process.",regulation of reproductive process,biological_process
94574,GO:2000242,"Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.",negative regulation of reproductive process,biological_process
94575,GO:2000243,"Any process that activates or increases the frequency, rate or extent of reproductive process.",positive regulation of reproductive process,biological_process
94576,GO:2000244,"Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.",regulation of FtsZ-dependent cytokinesis,biological_process
94577,GO:2000245,"Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.",negative regulation of FtsZ-dependent cytokinesis,biological_process
94578,GO:2000246,"Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis.",positive regulation of FtsZ-dependent cytokinesis,biological_process
94579,GO:2000247,"Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.",positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape,biological_process
94580,GO:2000248,"Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.",negative regulation of establishment or maintenance of neuroblast polarity,biological_process
94581,GO:2000252,"Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.",negative regulation of feeding behavior,biological_process
94582,GO:2000253,"Any process that activates or increases the frequency, rate or extent of feeding behavior.",positive regulation of feeding behavior,biological_process
94583,GO:2000254,"Any process that modulates the frequency, rate or extent of male germ cell proliferation.",regulation of male germ cell proliferation,biological_process
94584,GO:2000255,"Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.",negative regulation of male germ cell proliferation,biological_process
94585,GO:2000256,"Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.",positive regulation of male germ cell proliferation,biological_process
94586,GO:2000257,"Any process that modulates the frequency, rate or extent of protein activation cascade.",regulation of protein activation cascade,biological_process
94587,GO:2000258,"Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade.",negative regulation of protein activation cascade,biological_process
94588,GO:2000259,"Any process that activates or increases the frequency, rate or extent of protein activation cascade.",positive regulation of protein activation cascade,biological_process
94589,GO:2000260,"Any process that modulates the frequency, rate or extent of blood coagulation, common pathway.","regulation of blood coagulation, common pathway",biological_process
94590,GO:2000261,"Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway.","negative regulation of blood coagulation, common pathway",biological_process
94591,GO:2000262,"Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway.","positive regulation of blood coagulation, common pathway",biological_process
94592,GO:2000263,"Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway.","regulation of blood coagulation, extrinsic pathway",biological_process
94593,GO:2000264,"Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway.","negative regulation of blood coagulation, extrinsic pathway",biological_process
94594,GO:2000265,"Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway.","positive regulation of blood coagulation, extrinsic pathway",biological_process
94595,GO:2000266,"Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.","regulation of blood coagulation, intrinsic pathway",biological_process
94596,GO:2000267,"Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway.","negative regulation of blood coagulation, intrinsic pathway",biological_process
94597,GO:2000268,"Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway.","positive regulation of blood coagulation, intrinsic pathway",biological_process
94598,GO:2000269,"Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.",regulation of fibroblast apoptotic process,biological_process
94599,GO:2000270,"Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.",negative regulation of fibroblast apoptotic process,biological_process
94600,GO:2000271,"Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.",positive regulation of fibroblast apoptotic process,biological_process
94601,GO:2000272,"Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.",negative regulation of signaling receptor activity,biological_process
94602,GO:2000274,"Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.","regulation of epithelial cell migration, open tracheal system",biological_process
94603,GO:2000277,"Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.",positive regulation of oxidative phosphorylation uncoupler activity,biological_process
94604,GO:2000278,"Any process that modulates the frequency, rate or extent of DNA biosynthetic process.",regulation of DNA biosynthetic process,biological_process
94605,GO:2000279,"Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.",negative regulation of DNA biosynthetic process,biological_process
94606,GO:2000280,"Any process that modulates the frequency, rate or extent of root development.",regulation of root development,biological_process
94607,GO:2000282,"Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.",regulation of amino acid biosynthetic process,biological_process
94608,GO:2000283,"Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process.",negative regulation of amino acid biosynthetic process,biological_process
94609,GO:2000284,"Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.",positive regulation of amino acid biosynthetic process,biological_process
94610,GO:2000287,"Any process that activates or increases the frequency, rate or extent of myotome development.",positive regulation of myotome development,biological_process
94611,GO:2000288,"Any process that activates or increases the frequency, rate or extent of myoblast proliferation.",positive regulation of myoblast proliferation,biological_process
94612,GO:2000289,"Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance.",regulation of photoreceptor cell axon guidance,biological_process
94613,GO:2000290,"Any process that modulates the frequency, rate or extent of myotome development.",regulation of myotome development,biological_process
94614,GO:2000291,"Any process that modulates the frequency, rate or extent of myoblast proliferation.",regulation of myoblast proliferation,biological_process
94615,GO:2000292,"Any process that modulates the frequency, rate or extent of defecation.",regulation of defecation,biological_process
94616,GO:2000293,"Any process that stops, prevents or reduces the frequency, rate or extent of defecation.",negative regulation of defecation,biological_process
94617,GO:2000294,"Any process that activates or increases the frequency, rate or extent of defecation.",positive regulation of defecation,biological_process
94618,GO:2000295,"Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.",regulation of hydrogen peroxide catabolic process,biological_process
94619,GO:2000296,"Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.",negative regulation of hydrogen peroxide catabolic process,biological_process
94620,GO:2000297,"Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.",negative regulation of synapse maturation,biological_process
94621,GO:2000300,"Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.",regulation of synaptic vesicle exocytosis,biological_process
94622,GO:2000301,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.",negative regulation of synaptic vesicle exocytosis,biological_process
94623,GO:2000302,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.",positive regulation of synaptic vesicle exocytosis,biological_process
94624,GO:2000303,"Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.",regulation of ceramide biosynthetic process,biological_process
94625,GO:2000304,"Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.",positive regulation of ceramide biosynthetic process,biological_process
94626,GO:2000306,"Any process that activates or increases the frequency, rate or extent of photomorphogenesis.",positive regulation of photomorphogenesis,biological_process
94627,GO:2000307,"Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.",regulation of tumor necrosis factor (ligand) superfamily member 11 production,biological_process
94628,GO:2000308,"Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.",negative regulation of tumor necrosis factor (ligand) superfamily member 11 production,biological_process
94629,GO:2000309,"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.",positive regulation of tumor necrosis factor (ligand) superfamily member 11 production,biological_process
94630,GO:2000310,"Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.",regulation of NMDA receptor activity,biological_process
94631,GO:2000311,"Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.",regulation of AMPA receptor activity,biological_process
94632,GO:2000316,"Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.",regulation of T-helper 17 type immune response,biological_process
94633,GO:2000317,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.",negative regulation of T-helper 17 type immune response,biological_process
94634,GO:2000318,"Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.",positive regulation of T-helper 17 type immune response,biological_process
94635,GO:2000319,"Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.",regulation of T-helper 17 cell differentiation,biological_process
94636,GO:2000320,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.",negative regulation of T-helper 17 cell differentiation,biological_process
94637,GO:2000321,"Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.",positive regulation of T-helper 17 cell differentiation,biological_process
94638,GO:2000322,"Any process that modulates the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway.",regulation of nuclear receptor-mediated glucocorticoid signaling pathway,biological_process
94639,GO:2000323,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway.",negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway,biological_process
94640,GO:2000324,"Any process that activates or increases the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway.",positive regulation of nuclear receptor-mediated glucocorticoid signaling pathway,biological_process
94641,GO:2000328,"Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.",regulation of T-helper 17 cell lineage commitment,biological_process
94642,GO:2000329,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.",negative regulation of T-helper 17 cell lineage commitment,biological_process
94643,GO:2000330,"Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.",positive regulation of T-helper 17 cell lineage commitment,biological_process
94644,GO:2000331,"Any process that modulates the frequency, rate or extent of terminal button organization.",regulation of terminal button organization,biological_process
94645,GO:2000332,"Any process that modulates the frequency, rate or extent of blood microparticle formation.",regulation of blood microparticle formation,biological_process
94646,GO:2000333,"Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.",negative regulation of blood microparticle formation,biological_process
94647,GO:2000334,"Any process that activates or increases the frequency, rate or extent of blood microparticle formation.",positive regulation of blood microparticle formation,biological_process
94648,GO:2000335,"Any process that modulates the frequency, rate or extent of endothelial microparticle formation.",regulation of endothelial microparticle formation,biological_process
94649,GO:2000336,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.",negative regulation of endothelial microparticle formation,biological_process
94650,GO:2000337,"Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.",positive regulation of endothelial microparticle formation,biological_process
94651,GO:2000338,"Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.",regulation of chemokine (C-X-C motif) ligand 1 production,biological_process
94652,GO:2000339,"Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.",negative regulation of chemokine (C-X-C motif) ligand 1 production,biological_process
94653,GO:2000340,"Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.",positive regulation of chemokine (C-X-C motif) ligand 1 production,biological_process
94654,GO:2000341,"Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.",regulation of chemokine (C-X-C motif) ligand 2 production,biological_process
94655,GO:2000342,"Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.",negative regulation of chemokine (C-X-C motif) ligand 2 production,biological_process
94656,GO:2000343,"Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.",positive regulation of chemokine (C-X-C motif) ligand 2 production,biological_process
94657,GO:2000344,"Any process that activates or increases the frequency, rate or extent of the acrosome reaction.",positive regulation of acrosome reaction,biological_process
94658,GO:2000345,"Any process that modulates the frequency, rate or extent of hepatocyte proliferation.",regulation of hepatocyte proliferation,biological_process
94659,GO:2000346,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.",negative regulation of hepatocyte proliferation,biological_process
94660,GO:2000347,"Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.",positive regulation of hepatocyte proliferation,biological_process
94661,GO:2000348,"Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.",regulation of CD40 signaling pathway,biological_process
94662,GO:2000349,"Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.",negative regulation of CD40 signaling pathway,biological_process
94663,GO:2000350,"Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.",positive regulation of CD40 signaling pathway,biological_process
94664,GO:2000351,"Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.",regulation of endothelial cell apoptotic process,biological_process
94665,GO:2000352,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.",negative regulation of endothelial cell apoptotic process,biological_process
94666,GO:2000353,"Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.",positive regulation of endothelial cell apoptotic process,biological_process
94667,GO:2000354,"Any process that modulates the frequency, rate or extent of ovarian follicle development.",regulation of ovarian follicle development,biological_process
94668,GO:2000355,"Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.",negative regulation of ovarian follicle development,biological_process
94669,GO:2000356,"Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.",regulation of kidney smooth muscle cell differentiation,biological_process
94670,GO:2000357,"Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.",negative regulation of kidney smooth muscle cell differentiation,biological_process
94671,GO:2000358,"Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.",positive regulation of kidney smooth muscle cell differentiation,biological_process
94672,GO:2000359,"Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.",regulation of binding of sperm to zona pellucida,biological_process
94673,GO:2000360,"Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.",negative regulation of binding of sperm to zona pellucida,biological_process
94674,GO:2000367,"Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.",regulation of acrosomal vesicle exocytosis,biological_process
94675,GO:2000368,"Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.",positive regulation of acrosomal vesicle exocytosis,biological_process
94676,GO:2000369,"Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.",regulation of clathrin-dependent endocytosis,biological_process
94677,GO:2000370,"Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.",positive regulation of clathrin-dependent endocytosis,biological_process
94678,GO:2000373,"Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.",positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity,biological_process
94679,GO:2000374,"Any process that modulates the frequency, rate or extent of oxygen metabolic process.",regulation of oxygen metabolic process,biological_process
94680,GO:2000377,"Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.",regulation of reactive oxygen species metabolic process,biological_process
94681,GO:2000378,"Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.",negative regulation of reactive oxygen species metabolic process,biological_process
94682,GO:2000379,"Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.",positive regulation of reactive oxygen species metabolic process,biological_process
94683,GO:2000380,"Any process that modulates the frequency, rate or extent of mesoderm development.",regulation of mesoderm development,biological_process
94684,GO:2000381,"Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.",negative regulation of mesoderm development,biological_process
94685,GO:2000382,"Any process that activates or increases the frequency, rate or extent of mesoderm development.",positive regulation of mesoderm development,biological_process
94686,GO:2000383,"Any process that modulates the frequency, rate or extent of ectoderm development.",regulation of ectoderm development,biological_process
94687,GO:2000384,"Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.",negative regulation of ectoderm development,biological_process
94688,GO:2000385,"Any process that activates or increases the frequency, rate or extent of ectoderm development.",positive regulation of ectoderm development,biological_process
94689,GO:2000386,"Any process that activates or increases the frequency, rate or extent of ovarian follicle development.",positive regulation of ovarian follicle development,biological_process
94690,GO:2000387,"Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.",regulation of antral ovarian follicle growth,biological_process
94691,GO:2000388,"Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.",positive regulation of antral ovarian follicle growth,biological_process
94692,GO:2000389,"Any process that modulates the frequency, rate or extent of neutrophil extravasation.",regulation of neutrophil extravasation,biological_process
94693,GO:2000390,"Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation.",negative regulation of neutrophil extravasation,biological_process
94694,GO:2000391,"Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.",positive regulation of neutrophil extravasation,biological_process
94695,GO:2000392,"Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis.",regulation of lamellipodium morphogenesis,biological_process
94696,GO:2000393,"Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.",negative regulation of lamellipodium morphogenesis,biological_process
94697,GO:2000394,"Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.",positive regulation of lamellipodium morphogenesis,biological_process
94698,GO:2000395,"Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis.",regulation of ubiquitin-dependent endocytosis,biological_process
94699,GO:2000396,"Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis.",negative regulation of ubiquitin-dependent endocytosis,biological_process
94700,GO:2000397,"Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.",positive regulation of ubiquitin-dependent endocytosis,biological_process
94701,GO:2000398,"Any process that modulates the frequency, rate or extent of thymocyte aggregation.",regulation of thymocyte aggregation,biological_process
94702,GO:2000399,"Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation.",negative regulation of thymocyte aggregation,biological_process
94703,GO:2000400,"Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.",positive regulation of thymocyte aggregation,biological_process
94704,GO:2000401,"Any process that modulates the frequency, rate or extent of lymphocyte migration.",regulation of lymphocyte migration,biological_process
94705,GO:2000402,"Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.",negative regulation of lymphocyte migration,biological_process
94706,GO:2000403,"Any process that activates or increases the frequency, rate or extent of lymphocyte migration.",positive regulation of lymphocyte migration,biological_process
94707,GO:2000404,"Any process that modulates the frequency, rate or extent of T cell migration.",regulation of T cell migration,biological_process
94708,GO:2000405,"Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.",negative regulation of T cell migration,biological_process
94709,GO:2000406,"Any process that activates or increases the frequency, rate or extent of T cell migration.",positive regulation of T cell migration,biological_process
94710,GO:2000407,"Any process that modulates the frequency, rate or extent of T cell extravasation.",regulation of T cell extravasation,biological_process
94711,GO:2000408,"Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation.",negative regulation of T cell extravasation,biological_process
94712,GO:2000409,"Any process that activates or increases the frequency, rate or extent of T cell extravasation.",positive regulation of T cell extravasation,biological_process
94713,GO:2000410,"Any process that modulates the frequency, rate or extent of thymocyte migration.",regulation of thymocyte migration,biological_process
94714,GO:2000411,"Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.",negative regulation of thymocyte migration,biological_process
94715,GO:2000412,"Any process that activates or increases the frequency, rate or extent of thymocyte migration.",positive regulation of thymocyte migration,biological_process
94716,GO:2000413,"Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration.",regulation of fibronectin-dependent thymocyte migration,biological_process
94717,GO:2000414,"Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.",negative regulation of fibronectin-dependent thymocyte migration,biological_process
94718,GO:2000415,"Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.",positive regulation of fibronectin-dependent thymocyte migration,biological_process
94719,GO:2000416,"Any process that modulates the frequency, rate or extent of eosinophil migration.",regulation of eosinophil migration,biological_process
94720,GO:2000417,"Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.",negative regulation of eosinophil migration,biological_process
94721,GO:2000418,"Any process that activates or increases the frequency, rate or extent of eosinophil migration.",positive regulation of eosinophil migration,biological_process
94722,GO:2000419,"Any process that modulates the frequency, rate or extent of eosinophil extravasation.",regulation of eosinophil extravasation,biological_process
94723,GO:2000420,"Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.",negative regulation of eosinophil extravasation,biological_process
94724,GO:2000421,"Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.",positive regulation of eosinophil extravasation,biological_process
94725,GO:2000422,"Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.",regulation of eosinophil chemotaxis,biological_process
94726,GO:2000423,"Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.",negative regulation of eosinophil chemotaxis,biological_process
94727,GO:2000424,"Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.",positive regulation of eosinophil chemotaxis,biological_process
94728,GO:2000425,"Any process that modulates the frequency, rate or extent of apoptotic cell clearance.",regulation of apoptotic cell clearance,biological_process
94729,GO:2000426,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.",negative regulation of apoptotic cell clearance,biological_process
94730,GO:2000427,"Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.",positive regulation of apoptotic cell clearance,biological_process
94731,GO:2000428,"Any process that modulates the frequency, rate or extent of neutrophil aggregation.",regulation of neutrophil aggregation,biological_process
94732,GO:2000429,"Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation.",negative regulation of neutrophil aggregation,biological_process
94733,GO:2000430,"Any process that activates or increases the frequency, rate or extent of neutrophil aggregation.",positive regulation of neutrophil aggregation,biological_process
94734,GO:2000431,"Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.","regulation of cytokinesis, actomyosin contractile ring assembly",biological_process
94735,GO:2000432,"Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.","negative regulation of cytokinesis, actomyosin contractile ring assembly",biological_process
94736,GO:2000433,"Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.","positive regulation of cytokinesis, actomyosin contractile ring assembly",biological_process
94737,GO:2000434,"Any process that modulates the frequency, rate or extent of protein neddylation.",regulation of protein neddylation,biological_process
94738,GO:2000435,"Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation.",negative regulation of protein neddylation,biological_process
94739,GO:2000436,"Any process that activates or increases the frequency, rate or extent of protein neddylation.",positive regulation of protein neddylation,biological_process
94740,GO:2000437,"Any process that modulates the frequency, rate or extent of monocyte extravasation.",regulation of monocyte extravasation,biological_process
94741,GO:2000438,"Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.",negative regulation of monocyte extravasation,biological_process
94742,GO:2000439,"Any process that activates or increases the frequency, rate or extent of monocyte extravasation.",positive regulation of monocyte extravasation,biological_process
94743,GO:2000440,"Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.",regulation of toll-like receptor 15 signaling pathway,biological_process
94744,GO:2000441,"Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.",negative regulation of toll-like receptor 15 signaling pathway,biological_process
94745,GO:2000442,"Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.",positive regulation of toll-like receptor 15 signaling pathway,biological_process
94746,GO:2000443,"Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.",regulation of toll-like receptor 21 signaling pathway,biological_process
94747,GO:2000444,"Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.",negative regulation of toll-like receptor 21 signaling pathway,biological_process
94748,GO:2000445,"Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.",positive regulation of toll-like receptor 21 signaling pathway,biological_process
94749,GO:2000446,"Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.",regulation of macrophage migration inhibitory factor signaling pathway,biological_process
94750,GO:2000447,"Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.",negative regulation of macrophage migration inhibitory factor signaling pathway,biological_process
94751,GO:2000448,"Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.",positive regulation of macrophage migration inhibitory factor signaling pathway,biological_process
94752,GO:2000449,"Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.","regulation of CD8-positive, alpha-beta T cell extravasation",biological_process
94753,GO:2000450,"Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.","negative regulation of CD8-positive, alpha-beta T cell extravasation",biological_process
94754,GO:2000451,"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.","positive regulation of CD8-positive, alpha-beta T cell extravasation",biological_process
94755,GO:2000452,"Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.","regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation",biological_process
94756,GO:2000453,"Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.","negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation",biological_process
94757,GO:2000454,"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.","positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation",biological_process
94758,GO:2000455,"Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.",regulation of T-helper 17 cell extravasation,biological_process
94759,GO:2000456,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.",negative regulation of T-helper 17 cell extravasation,biological_process
94760,GO:2000457,"Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation.",positive regulation of T-helper 17 cell extravasation,biological_process
94761,GO:2000458,"Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.",regulation of astrocyte chemotaxis,biological_process
94762,GO:2000459,"Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.",negative regulation of astrocyte chemotaxis,biological_process
94763,GO:2000463,Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.,positive regulation of excitatory postsynaptic potential,biological_process
94764,GO:2000464,"Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.",positive regulation of astrocyte chemotaxis,biological_process
94765,GO:2000465,"Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.",regulation of glycogen (starch) synthase activity,biological_process
94766,GO:2000466,"Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.",negative regulation of glycogen (starch) synthase activity,biological_process
94767,GO:2000467,"Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.",positive regulation of glycogen (starch) synthase activity,biological_process
94768,GO:2000471,"Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.",regulation of hematopoietic stem cell migration,biological_process
94769,GO:2000472,"Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.",negative regulation of hematopoietic stem cell migration,biological_process
94770,GO:2000473,"Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.",positive regulation of hematopoietic stem cell migration,biological_process
94771,GO:2000474,"Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway.",regulation of opioid receptor signaling pathway,biological_process
94772,GO:2000475,"Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.",negative regulation of opioid receptor signaling pathway,biological_process
94773,GO:2000476,"Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.",positive regulation of opioid receptor signaling pathway,biological_process
94774,GO:2000477,"Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.",regulation of metanephric podocyte development,biological_process
94775,GO:2000478,"Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.",positive regulation of metanephric podocyte development,biological_process
94776,GO:2000479,"Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.",regulation of cAMP-dependent protein kinase activity,biological_process
94777,GO:2000480,"Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.",negative regulation of cAMP-dependent protein kinase activity,biological_process
94778,GO:2000481,"Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.",positive regulation of cAMP-dependent protein kinase activity,biological_process
94779,GO:2000485,"Any process that modulates the frequency, rate or extent of glutamine transport.",regulation of glutamine transport,biological_process
94780,GO:2000486,"Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.",negative regulation of glutamine transport,biological_process
94781,GO:2000487,"Any process that activates or increases the frequency, rate or extent of glutamine transport.",positive regulation of glutamine transport,biological_process
94782,GO:2000488,"Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.",positive regulation of brassinosteroid biosynthetic process,biological_process
94783,GO:2000489,"Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.",regulation of hepatic stellate cell activation,biological_process
94784,GO:2000490,"Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.",negative regulation of hepatic stellate cell activation,biological_process
94785,GO:2000491,"Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.",positive regulation of hepatic stellate cell activation,biological_process
94786,GO:2000492,"Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.",regulation of interleukin-18-mediated signaling pathway,biological_process
94787,GO:2000493,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.",negative regulation of interleukin-18-mediated signaling pathway,biological_process
94788,GO:2000494,"Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway.",positive regulation of interleukin-18-mediated signaling pathway,biological_process
94789,GO:2000495,"Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.",regulation of cell proliferation involved in compound eye morphogenesis,biological_process
94790,GO:2000497,"Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.",positive regulation of cell proliferation involved in compound eye morphogenesis,biological_process
94791,GO:2000501,"Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.",regulation of natural killer cell chemotaxis,biological_process
94792,GO:2000502,"Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.",negative regulation of natural killer cell chemotaxis,biological_process
94793,GO:2000503,"Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.",positive regulation of natural killer cell chemotaxis,biological_process
94794,GO:2000504,"Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.",positive regulation of blood vessel remodeling,biological_process
94795,GO:2000508,"Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.",regulation of dendritic cell chemotaxis,biological_process
94796,GO:2000509,"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.",negative regulation of dendritic cell chemotaxis,biological_process
94797,GO:2000510,"Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.",positive regulation of dendritic cell chemotaxis,biological_process
94798,GO:2000511,"Any process that modulates the frequency, rate or extent of granzyme A production.",regulation of granzyme A production,biological_process
94799,GO:2000512,"Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.",negative regulation of granzyme A production,biological_process
94800,GO:2000513,"Any process that activates or increases the frequency, rate or extent of granzyme A production.",positive regulation of granzyme A production,biological_process
94801,GO:2000514,"Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.","regulation of CD4-positive, alpha-beta T cell activation",biological_process
94802,GO:2000515,"Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.","negative regulation of CD4-positive, alpha-beta T cell activation",biological_process
94803,GO:2000516,"Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.","positive regulation of CD4-positive, alpha-beta T cell activation",biological_process
94804,GO:2000517,"Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.",regulation of T-helper 1 cell activation,biological_process
94805,GO:2000518,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.",negative regulation of T-helper 1 cell activation,biological_process
94806,GO:2000519,"Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation.",positive regulation of T-helper 1 cell activation,biological_process
94807,GO:2000520,"Any process that modulates the frequency, rate or extent of immunological synapse formation.",regulation of immunological synapse formation,biological_process
94808,GO:2000521,"Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.",negative regulation of immunological synapse formation,biological_process
94809,GO:2000522,"Any process that activates or increases the frequency, rate or extent of immunological synapse formation.",positive regulation of immunological synapse formation,biological_process
94810,GO:2000523,"Any process that modulates the frequency, rate or extent of T cell costimulation.",regulation of T cell costimulation,biological_process
94811,GO:2000524,"Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.",negative regulation of T cell costimulation,biological_process
94812,GO:2000525,"Any process that activates or increases the frequency, rate or extent of T cell costimulation.",positive regulation of T cell costimulation,biological_process
94813,GO:2000527,"Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.",regulation of myeloid dendritic cell chemotaxis,biological_process
94814,GO:2000528,"Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.",negative regulation of myeloid dendritic cell chemotaxis,biological_process
94815,GO:2000529,"Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.",positive regulation of myeloid dendritic cell chemotaxis,biological_process
94816,GO:2000532,"Any process that modulates the frequency, rate or extent of renal albumin absorption.",regulation of renal albumin absorption,biological_process
94817,GO:2000533,"Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.",negative regulation of renal albumin absorption,biological_process
94818,GO:2000534,"Any process that activates or increases the frequency, rate or extent of renal albumin absorption.",positive regulation of renal albumin absorption,biological_process
94819,GO:2000535,"Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.",regulation of entry of bacterium into host cell,biological_process
94820,GO:2000536,"Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.",negative regulation of entry of bacterium into host cell,biological_process
94821,GO:2000537,"Any process that modulates the frequency, rate or extent of B cell chemotaxis.",regulation of B cell chemotaxis,biological_process
94822,GO:2000538,"Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.",positive regulation of B cell chemotaxis,biological_process
94823,GO:2000539,"Any process that modulates the frequency, rate or extent of protein geranylgeranylation.",regulation of protein geranylgeranylation,biological_process
94824,GO:2000540,"Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation.",negative regulation of protein geranylgeranylation,biological_process
94825,GO:2000541,"Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.",positive regulation of protein geranylgeranylation,biological_process
94826,GO:2000542,"Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.",negative regulation of gastrulation,biological_process
94827,GO:2000543,"Any process that activates or increases the frequency, rate or extent of gastrulation.",positive regulation of gastrulation,biological_process
94828,GO:2000544,"Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.",regulation of endothelial cell chemotaxis to fibroblast growth factor,biological_process
94829,GO:2000545,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.",negative regulation of endothelial cell chemotaxis to fibroblast growth factor,biological_process
94830,GO:2000546,"Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.",positive regulation of endothelial cell chemotaxis to fibroblast growth factor,biological_process
94831,GO:2000547,"Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.",regulation of dendritic cell dendrite assembly,biological_process
94832,GO:2000548,"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.",negative regulation of dendritic cell dendrite assembly,biological_process
94833,GO:2000549,"Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.",positive regulation of dendritic cell dendrite assembly,biological_process
94834,GO:2000550,"Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.",negative regulation of B cell chemotaxis,biological_process
94835,GO:2000551,"Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.",regulation of T-helper 2 cell cytokine production,biological_process
94836,GO:2000552,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.",negative regulation of T-helper 2 cell cytokine production,biological_process
94837,GO:2000553,"Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.",positive regulation of T-helper 2 cell cytokine production,biological_process
94838,GO:2000554,"Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.",regulation of T-helper 1 cell cytokine production,biological_process
94839,GO:2000555,"Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.",negative regulation of T-helper 1 cell cytokine production,biological_process
94840,GO:2000556,"Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.",positive regulation of T-helper 1 cell cytokine production,biological_process
94841,GO:2000557,"Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue.",regulation of immunoglobulin production in mucosal tissue,biological_process
94842,GO:2000558,"Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue.",positive regulation of immunoglobulin production in mucosal tissue,biological_process
94843,GO:2000561,"Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.","regulation of CD4-positive, alpha-beta T cell proliferation",biological_process
94844,GO:2000562,"Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.","negative regulation of CD4-positive, alpha-beta T cell proliferation",biological_process
94845,GO:2000563,"Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.","positive regulation of CD4-positive, alpha-beta T cell proliferation",biological_process
94846,GO:2000564,"Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.","regulation of CD8-positive, alpha-beta T cell proliferation",biological_process
94847,GO:2000565,"Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.","negative regulation of CD8-positive, alpha-beta T cell proliferation",biological_process
94848,GO:2000566,"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.","positive regulation of CD8-positive, alpha-beta T cell proliferation",biological_process
94849,GO:2000567,"Any process that modulates the frequency, rate or extent of memory T cell activation.",regulation of memory T cell activation,biological_process
94850,GO:2000568,"Any process that activates or increases the frequency, rate or extent of memory T cell activation.",positive regulation of memory T cell activation,biological_process
94851,GO:2000569,"Any process that modulates the frequency, rate or extent of T-helper 2 cell activation.",regulation of T-helper 2 cell activation,biological_process
94852,GO:2000570,"Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.",positive regulation of T-helper 2 cell activation,biological_process
94853,GO:2000571,"Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.",regulation of interleukin-4-dependent isotype switching to IgE isotypes,biological_process
94854,GO:2000572,"Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.",positive regulation of interleukin-4-dependent isotype switching to IgE isotypes,biological_process
94855,GO:2000573,"Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.",positive regulation of DNA biosynthetic process,biological_process
94856,GO:2000583,"Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.",regulation of platelet-derived growth factor receptor-alpha signaling pathway,biological_process
94857,GO:2000584,"Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.",negative regulation of platelet-derived growth factor receptor-alpha signaling pathway,biological_process
94858,GO:2000585,"Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.",positive regulation of platelet-derived growth factor receptor-alpha signaling pathway,biological_process
94859,GO:2000586,"Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.",regulation of platelet-derived growth factor receptor-beta signaling pathway,biological_process
94860,GO:2000587,"Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.",negative regulation of platelet-derived growth factor receptor-beta signaling pathway,biological_process
94861,GO:2000588,"Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.",positive regulation of platelet-derived growth factor receptor-beta signaling pathway,biological_process
94862,GO:2000589,"Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.",regulation of metanephric mesenchymal cell migration,biological_process
94863,GO:2000590,"Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.",negative regulation of metanephric mesenchymal cell migration,biological_process
94864,GO:2000591,"Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.",positive regulation of metanephric mesenchymal cell migration,biological_process
94865,GO:2000592,"Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation.",regulation of metanephric DCT cell differentiation,biological_process
94866,GO:2000593,"Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation.",negative regulation of metanephric DCT cell differentiation,biological_process
94867,GO:2000594,"Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.",positive regulation of metanephric DCT cell differentiation,biological_process
94868,GO:2000595,"Any process that modulates the frequency, rate or extent of optic nerve formation.",regulation of optic nerve formation,biological_process
94869,GO:2000596,"Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.",negative regulation of optic nerve formation,biological_process
94870,GO:2000597,"Any process that activates or increases the frequency, rate or extent of optic nerve formation.",positive regulation of optic nerve formation,biological_process
94871,GO:2000601,"Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.",positive regulation of Arp2/3 complex-mediated actin nucleation,biological_process
94872,GO:2000603,"Any process that modulates the frequency, rate or extent of secondary growth.",regulation of secondary growth,biological_process
94873,GO:2000604,"Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth.",negative regulation of secondary growth,biological_process
94874,GO:2000605,"Any process that activates or increases the frequency, rate or extent of secondary growth.",positive regulation of secondary growth,biological_process
94875,GO:2000609,"Any process that modulates the frequency, rate or extent of thyroid hormone generation.",regulation of thyroid hormone generation,biological_process
94876,GO:2000610,"Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.",negative regulation of thyroid hormone generation,biological_process
94877,GO:2000611,"Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.",positive regulation of thyroid hormone generation,biological_process
94878,GO:2000612,"Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.",regulation of thyroid-stimulating hormone secretion,biological_process
94879,GO:2000613,"Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.",negative regulation of thyroid-stimulating hormone secretion,biological_process
94880,GO:2000614,"Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.",positive regulation of thyroid-stimulating hormone secretion,biological_process
94881,GO:2000621,"Any process that modulates the frequency, rate or extent of DNA replication termination.",regulation of DNA replication termination,biological_process
94882,GO:2000622,"Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.","regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",biological_process
94883,GO:2000623,"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.","negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",biological_process
94884,GO:2000624,"Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.","positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",biological_process
94885,GO:2000625,"Any process that modulates the frequency, rate or extent of miRNA catabolic process.",regulation of miRNA catabolic process,biological_process
94886,GO:2000626,"Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.",negative regulation of miRNA catabolic process,biological_process
94887,GO:2000627,"Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.",positive regulation of miRNA catabolic process,biological_process
94888,GO:2000628,"Any process that modulates the frequency, rate or extent of miRNA metabolic process.",regulation of miRNA metabolic process,biological_process
94889,GO:2000629,"Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.",negative regulation of miRNA metabolic process,biological_process
94890,GO:2000630,"Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.",positive regulation of miRNA metabolic process,biological_process
94891,GO:2000631,"Any process that modulates the frequency, rate or extent of pre-microRNA processing.",regulation of pre-miRNA processing,biological_process
94892,GO:2000632,"Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.",negative regulation of pre-miRNA processing,biological_process
94893,GO:2000633,"Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.",positive regulation of pre-miRNA processing,biological_process
94894,GO:2000634,"Any process that modulates the frequency, rate or extent of primary microRNA processing.",regulation of primary miRNA processing,biological_process
94895,GO:2000635,"Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.",negative regulation of primary miRNA processing,biological_process
94896,GO:2000636,"Any process that activates or increases the frequency, rate or extent of primary microRNA processing.",positive regulation of primary miRNA processing,biological_process
94897,GO:2000637,"A process that activates or increases the frequency, rate or extent of gene silencing by a microRNA (miRNA).",positive regulation of miRNA-mediated gene silencing,biological_process
94898,GO:2000638,"Any process that modulates the frequency, rate or extent of the SREBP signaling pathway.",regulation of SREBP signaling pathway,biological_process
94899,GO:2000639,"Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.",negative regulation of SREBP signaling pathway,biological_process
94900,GO:2000640,"Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.",positive regulation of SREBP signaling pathway,biological_process
94901,GO:2000641,"Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.",regulation of early endosome to late endosome transport,biological_process
94902,GO:2000642,"Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.",negative regulation of early endosome to late endosome transport,biological_process
94903,GO:2000643,"Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.",positive regulation of early endosome to late endosome transport,biological_process
94904,GO:2000644,"Any process that modulates the frequency, rate or extent of receptor catabolic process.",regulation of receptor catabolic process,biological_process
94905,GO:2000645,"Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.",negative regulation of receptor catabolic process,biological_process
94906,GO:2000646,"Any process that activates or increases the frequency, rate or extent of receptor catabolic process.",positive regulation of receptor catabolic process,biological_process
94907,GO:2000647,"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.",negative regulation of stem cell proliferation,biological_process
94908,GO:2000648,"Any process that activates or increases the frequency, rate or extent of stem cell proliferation.",positive regulation of stem cell proliferation,biological_process
94909,GO:2000649,"Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.",regulation of sodium ion transmembrane transporter activity,biological_process
94910,GO:2000651,"Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.",positive regulation of sodium ion transmembrane transporter activity,biological_process
94911,GO:2000652,"Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.",regulation of secondary cell wall biogenesis,biological_process
94912,GO:2000654,"Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.",regulation of cellular response to testosterone stimulus,biological_process
94913,GO:2000655,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.",negative regulation of cellular response to testosterone stimulus,biological_process
94914,GO:2000659,"Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.",regulation of interleukin-1-mediated signaling pathway,biological_process
94915,GO:2000660,"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.",negative regulation of interleukin-1-mediated signaling pathway,biological_process
94916,GO:2000661,"Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.",positive regulation of interleukin-1-mediated signaling pathway,biological_process
94917,GO:2000668,"Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.",regulation of dendritic cell apoptotic process,biological_process
94918,GO:2000669,"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.",negative regulation of dendritic cell apoptotic process,biological_process
94919,GO:2000670,"Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.",positive regulation of dendritic cell apoptotic process,biological_process
94920,GO:2000671,"Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.",regulation of motor neuron apoptotic process,biological_process
94921,GO:2000672,"Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.",negative regulation of motor neuron apoptotic process,biological_process
94922,GO:2000673,"Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.",positive regulation of motor neuron apoptotic process,biological_process
94923,GO:2000674,"Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.",regulation of type B pancreatic cell apoptotic process,biological_process
94924,GO:2000675,"Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.",negative regulation of type B pancreatic cell apoptotic process,biological_process
94925,GO:2000676,"Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.",positive regulation of type B pancreatic cell apoptotic process,biological_process
94926,GO:2000677,"Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.",regulation of transcription regulatory region DNA binding,biological_process
94927,GO:2000678,"Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.",negative regulation of transcription regulatory region DNA binding,biological_process
94928,GO:2000679,"Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.",positive regulation of transcription regulatory region DNA binding,biological_process
94929,GO:2000683,"Any process that modulates the frequency, rate or extent of cellular response to X-ray.",regulation of cellular response to X-ray,biological_process
94930,GO:2000684,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.",negative regulation of cellular response to X-ray,biological_process
94931,GO:2000685,"Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.",positive regulation of cellular response to X-ray,biological_process
94932,GO:2000689,An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.,actomyosin contractile ring assembly actin filament organization,biological_process
94933,GO:2000690,"Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.",regulation of cardiac muscle cell myoblast differentiation,biological_process
94934,GO:2000691,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.",negative regulation of cardiac muscle cell myoblast differentiation,biological_process
94935,GO:2000692,"Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.",negative regulation of seed maturation,biological_process
94936,GO:2000693,"Any process that activates or increases the frequency, rate or extent of seed maturation.",positive regulation of seed maturation,biological_process
94937,GO:2000694,"Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.",regulation of phragmoplast microtubule organization,biological_process
94938,GO:2000696,"Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.",regulation of epithelial cell differentiation involved in kidney development,biological_process
94939,GO:2000697,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.",negative regulation of epithelial cell differentiation involved in kidney development,biological_process
94940,GO:2000700,"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.",positive regulation of cardiac muscle cell myoblast differentiation,biological_process
94941,GO:2000705,"Any process that modulates the frequency, rate or extent of dense core granule biogenesis.",regulation of dense core granule biogenesis,biological_process
94942,GO:2000706,"Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.",negative regulation of dense core granule biogenesis,biological_process
94943,GO:2000707,"Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.",positive regulation of dense core granule biogenesis,biological_process
94944,GO:2000709,"Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.","regulation of maintenance of meiotic sister chromatid cohesion, centromeric",biological_process
94945,GO:2000710,"Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.","negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric",biological_process
94946,GO:2000711,"Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.","positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric",biological_process
94947,GO:2000715,"Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.","regulation of maintenance of mitotic sister chromatid cohesion, arms",biological_process
94948,GO:2000716,"Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.","negative regulation of maintenance of mitotic sister chromatid cohesion, arms",biological_process
94949,GO:2000717,"Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.","positive regulation of maintenance of mitotic sister chromatid cohesion, arms",biological_process
94950,GO:2000718,"Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.","regulation of maintenance of mitotic sister chromatid cohesion, centromeric",biological_process
94951,GO:2000719,"Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.","negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric",biological_process
94952,GO:2000720,"Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.","positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric",biological_process
94953,GO:2000722,"Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.",regulation of cardiac vascular smooth muscle cell differentiation,biological_process
94954,GO:2000723,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.",negative regulation of cardiac vascular smooth muscle cell differentiation,biological_process
94955,GO:2000724,"Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.",positive regulation of cardiac vascular smooth muscle cell differentiation,biological_process
94956,GO:2000725,"Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.",regulation of cardiac muscle cell differentiation,biological_process
94957,GO:2000726,"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.",negative regulation of cardiac muscle cell differentiation,biological_process
94958,GO:2000727,"Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.",positive regulation of cardiac muscle cell differentiation,biological_process
94959,GO:2000728,"Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.",regulation of mRNA export from nucleus in response to heat stress,biological_process
94960,GO:2000729,"Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.",positive regulation of mesenchymal cell proliferation involved in ureter development,biological_process
94961,GO:2000730,"Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.",regulation of termination of RNA polymerase I transcription,biological_process
94962,GO:2000731,"Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.",negative regulation of termination of RNA polymerase I transcription,biological_process
94963,GO:2000732,"Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.",positive regulation of termination of RNA polymerase I transcription,biological_process
94964,GO:2000736,"Any process that modulates the frequency, rate or extent of stem cell differentiation.",regulation of stem cell differentiation,biological_process
94965,GO:2000737,"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.",negative regulation of stem cell differentiation,biological_process
94966,GO:2000738,"Any process that activates or increases the frequency, rate or extent of stem cell differentiation.",positive regulation of stem cell differentiation,biological_process
94967,GO:2000739,"Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.",regulation of mesenchymal stem cell differentiation,biological_process
94968,GO:2000740,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.",negative regulation of mesenchymal stem cell differentiation,biological_process
94969,GO:2000741,"Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.",positive regulation of mesenchymal stem cell differentiation,biological_process
94970,GO:2000742,"Any process that modulates the frequency, rate or extent of anterior head development.",regulation of anterior head development,biological_process
94971,GO:2000743,"Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.",negative regulation of anterior head development,biological_process
94972,GO:2000744,"Any process that activates or increases the frequency, rate or extent of anterior head development.",positive regulation of anterior head development,biological_process
94973,GO:2000746,"Any process that modulates the frequency, rate or extent of defecation rhythm.",regulation of defecation rhythm,biological_process
94974,GO:2000747,"Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.",negative regulation of defecation rhythm,biological_process
94975,GO:2000748,"Any process that activates or increases the frequency, rate or extent of defecation rhythm.",positive regulation of defecation rhythm,biological_process
94976,GO:2000749,"Any process that activates or increases the frequency, rate or extent of rDNA heterochromatin formation.",positive regulation of rDNA heterochromatin formation,biological_process
94977,GO:2000750,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.",negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape,biological_process
94978,GO:2000752,"Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process.",regulation of glucosylceramide catabolic process,biological_process
94979,GO:2000753,"Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.",positive regulation of glucosylceramide catabolic process,biological_process
94980,GO:2000754,"Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process.",regulation of sphingomyelin catabolic process,biological_process
94981,GO:2000755,"Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.",positive regulation of sphingomyelin catabolic process,biological_process
94982,GO:2000756,"Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation.",regulation of peptidyl-lysine acetylation,biological_process
94983,GO:2000757,"Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.",negative regulation of peptidyl-lysine acetylation,biological_process
94984,GO:2000758,"Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation.",positive regulation of peptidyl-lysine acetylation,biological_process
94985,GO:2000759,"Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.",regulation of N-terminal peptidyl-lysine acetylation,biological_process
94986,GO:2000760,"Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.",negative regulation of N-terminal peptidyl-lysine acetylation,biological_process
94987,GO:2000761,"Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.",positive regulation of N-terminal peptidyl-lysine acetylation,biological_process
94988,GO:2000762,"Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.",regulation of phenylpropanoid metabolic process,biological_process
94989,GO:2000765,"Any process that modulates the frequency, rate or extent of cytoplasmic translation.",regulation of cytoplasmic translation,biological_process
94990,GO:2000766,"Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.",negative regulation of cytoplasmic translation,biological_process
94991,GO:2000767,"Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.",positive regulation of cytoplasmic translation,biological_process
94992,GO:2000768,"Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.",positive regulation of nephron tubule epithelial cell differentiation,biological_process
94993,GO:2000769,"Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.",regulation of establishment or maintenance of cell polarity regulating cell shape,biological_process
94994,GO:2000770,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.",negative regulation of establishment or maintenance of cell polarity regulating cell shape,biological_process
94995,GO:2000771,"Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.",positive regulation of establishment or maintenance of cell polarity regulating cell shape,biological_process
94996,GO:2000772,"Any process that modulates the frequency, rate or extent of cellular senescence.",regulation of cellular senescence,biological_process
94997,GO:2000773,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.",negative regulation of cellular senescence,biological_process
94998,GO:2000774,"Any process that activates or increases the frequency, rate or extent of cellular senescence.",positive regulation of cellular senescence,biological_process
94999,GO:2000779,"Any process that modulates the frequency, rate or extent of double-strand break repair.",regulation of double-strand break repair,biological_process
95000,GO:2000780,"Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.",negative regulation of double-strand break repair,biological_process
95001,GO:2000781,"Any process that activates or increases the frequency, rate or extent of double-strand break repair.",positive regulation of double-strand break repair,biological_process
95002,GO:2000782,"Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.",regulation of establishment of cell polarity regulating cell shape,biological_process
95003,GO:2000783,"Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape.",negative regulation of establishment of cell polarity regulating cell shape,biological_process
95004,GO:2000784,"Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.",positive regulation of establishment of cell polarity regulating cell shape,biological_process
95005,GO:2000785,"Any process that modulates the frequency, rate or extent of autophagosome assembly.",regulation of autophagosome assembly,biological_process
95006,GO:2000786,"Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.",positive regulation of autophagosome assembly,biological_process
95007,GO:2000787,"Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.",regulation of venous endothelial cell fate commitment,biological_process
95008,GO:2000788,"Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment.",negative regulation of venous endothelial cell fate commitment,biological_process
95009,GO:2000789,"Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.",positive regulation of venous endothelial cell fate commitment,biological_process
95010,GO:2000791,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.",negative regulation of mesenchymal cell proliferation involved in lung development,biological_process
95011,GO:2000793,Any cell proliferation that is involved in heart valve development.,cell proliferation involved in heart valve development,biological_process
95012,GO:2000794,"Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.",regulation of epithelial cell proliferation involved in lung morphogenesis,biological_process
95013,GO:2000795,"Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.",negative regulation of epithelial cell proliferation involved in lung morphogenesis,biological_process
95014,GO:2000797,"Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.",regulation of amniotic stem cell differentiation,biological_process
95015,GO:2000798,"Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.",negative regulation of amniotic stem cell differentiation,biological_process
95016,GO:2000799,"Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation.",positive regulation of amniotic stem cell differentiation,biological_process
95017,GO:2000800,"Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.",regulation of endocardial cushion to mesenchymal transition involved in heart valve formation,biological_process
95018,GO:2000802,"Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.",positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation,biological_process
95019,GO:2000804,"Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.","regulation of termination of RNA polymerase II transcription, poly(A)-coupled",biological_process
95020,GO:2000805,"Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.","negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled",biological_process
95021,GO:2000806,"Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.","positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled",biological_process
95022,GO:2000807,"Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.",regulation of synaptic vesicle clustering,biological_process
95023,GO:2000808,"Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.",negative regulation of synaptic vesicle clustering,biological_process
95024,GO:2000809,"Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.",positive regulation of synaptic vesicle clustering,biological_process
95025,GO:2000810,"Any process that modulates the frequency, rate or extent of tight junction assembly.",regulation of bicellular tight junction assembly,biological_process
95026,GO:2000811,"Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.",negative regulation of anoikis,biological_process
95027,GO:2000812,"Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.",regulation of barbed-end actin filament capping,biological_process
95028,GO:2000813,"Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.",negative regulation of barbed-end actin filament capping,biological_process
95029,GO:2000814,"Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.",positive regulation of barbed-end actin filament capping,biological_process
95030,GO:2000815,A process of regulation of mRNA stability that is involved in a response to oxidative stress.,regulation of mRNA stability involved in response to oxidative stress,biological_process
95031,GO:2000816,"Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.",negative regulation of mitotic sister chromatid separation,biological_process
95032,GO:2000818,"Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.",negative regulation of myoblast proliferation,biological_process
95033,GO:2000819,"Any process that modulates the frequency, rate or extent of nucleotide-excision repair.",regulation of nucleotide-excision repair,biological_process
95034,GO:2000821,"Any process that modulates the frequency, rate or extent of grooming behavior.",regulation of grooming behavior,biological_process
95035,GO:2000822,"Any process that modulates the frequency, rate or extent of behavioral fear response.",regulation of behavioral fear response,biological_process
95036,GO:2000826,"Any process that modulates the frequency, rate or extent of heart morphogenesis.",regulation of heart morphogenesis,biological_process
95037,GO:2000827,The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.,mitochondrial RNA surveillance,biological_process
95038,GO:2000828,"Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.",regulation of parathyroid hormone secretion,biological_process
95039,GO:2000829,"Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.",negative regulation of parathyroid hormone secretion,biological_process
95040,GO:2000830,"Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.",positive regulation of parathyroid hormone secretion,biological_process
95041,GO:2000831,"Any process that modulates the frequency, rate or extent of steroid hormone secretion.",regulation of steroid hormone secretion,biological_process
95042,GO:2000832,"Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.",negative regulation of steroid hormone secretion,biological_process
95043,GO:2000833,"Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.",positive regulation of steroid hormone secretion,biological_process
95044,GO:2000834,"Any process that modulates the frequency, rate or extent of androgen secretion.",regulation of androgen secretion,biological_process
95045,GO:2000835,"Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.",negative regulation of androgen secretion,biological_process
95046,GO:2000836,"Any process that activates or increases the frequency, rate or extent of androgen secretion.",positive regulation of androgen secretion,biological_process
95047,GO:2000837,"Any process that modulates the frequency, rate or extent of androstenedione secretion.",regulation of androstenedione secretion,biological_process
95048,GO:2000838,"Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.",negative regulation of androstenedione secretion,biological_process
95049,GO:2000839,"Any process that activates or increases the frequency, rate or extent of androstenedione secretion.",positive regulation of androstenedione secretion,biological_process
95050,GO:2000840,"Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.",regulation of dehydroepiandrosterone secretion,biological_process
95051,GO:2000841,"Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.",negative regulation of dehydroepiandrosterone secretion,biological_process
95052,GO:2000842,"Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion.",positive regulation of dehydroepiandrosterone secretion,biological_process
95053,GO:2000843,"Any process that modulates the frequency, rate or extent of testosterone secretion.",regulation of testosterone secretion,biological_process
95054,GO:2000844,"Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.",negative regulation of testosterone secretion,biological_process
95055,GO:2000845,"Any process that activates or increases the frequency, rate or extent of testosterone secretion.",positive regulation of testosterone secretion,biological_process
95056,GO:2000846,"Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.",regulation of corticosteroid hormone secretion,biological_process
95057,GO:2000847,"Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.",negative regulation of corticosteroid hormone secretion,biological_process
95058,GO:2000848,"Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.",positive regulation of corticosteroid hormone secretion,biological_process
95059,GO:2000849,"Any process that modulates the frequency, rate or extent of glucocorticoid secretion.",regulation of glucocorticoid secretion,biological_process
95060,GO:2000850,"Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.",negative regulation of glucocorticoid secretion,biological_process
95061,GO:2000851,"Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.",positive regulation of glucocorticoid secretion,biological_process
95062,GO:2000852,"Any process that modulates the frequency, rate or extent of corticosterone secretion.",regulation of corticosterone secretion,biological_process
95063,GO:2000853,"Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.",negative regulation of corticosterone secretion,biological_process
95064,GO:2000854,"Any process that activates or increases the frequency, rate or extent of corticosterone secretion.",positive regulation of corticosterone secretion,biological_process
95065,GO:2000855,"Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.",regulation of mineralocorticoid secretion,biological_process
95066,GO:2000856,"Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.",negative regulation of mineralocorticoid secretion,biological_process
95067,GO:2000857,"Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.",positive regulation of mineralocorticoid secretion,biological_process
95068,GO:2000858,"Any process that modulates the frequency, rate or extent of aldosterone secretion.",regulation of aldosterone secretion,biological_process
95069,GO:2000859,"Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.",negative regulation of aldosterone secretion,biological_process
95070,GO:2000860,"Any process that activates or increases the frequency, rate or extent of aldosterone secretion.",positive regulation of aldosterone secretion,biological_process
95071,GO:2000861,"Any process that modulates the frequency, rate or extent of estrogen secretion.",regulation of estrogen secretion,biological_process
95072,GO:2000862,"Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.",negative regulation of estrogen secretion,biological_process
95073,GO:2000863,"Any process that activates or increases the frequency, rate or extent of estrogen secretion.",positive regulation of estrogen secretion,biological_process
95074,GO:2000864,"Any process that modulates the frequency, rate or extent of estradiol secretion.",regulation of estradiol secretion,biological_process
95075,GO:2000865,"Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.",negative regulation of estradiol secretion,biological_process
95076,GO:2000866,"Any process that activates or increases the frequency, rate or extent of estradiol secretion.",positive regulation of estradiol secretion,biological_process
95077,GO:2000867,"Any process that modulates the frequency, rate or extent of estrone secretion.",regulation of estrone secretion,biological_process
95078,GO:2000868,"Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.",negative regulation of estrone secretion,biological_process
95079,GO:2000869,"Any process that activates or increases the frequency, rate or extent of estrone secretion.",positive regulation of estrone secretion,biological_process
95080,GO:2000870,"Any process that modulates the frequency, rate or extent of progesterone secretion.",regulation of progesterone secretion,biological_process
95081,GO:2000871,"Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.",negative regulation of progesterone secretion,biological_process
95082,GO:2000872,"Any process that activates or increases the frequency, rate or extent of progesterone secretion.",positive regulation of progesterone secretion,biological_process
95083,GO:2000874,"Any process that modulates the frequency, rate or extent of glyoxylate cycle.",regulation of glyoxylate cycle,biological_process
95084,GO:2000875,"Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle.",negative regulation of glyoxylate cycle,biological_process
95085,GO:2000876,"Any process that activates or increases the frequency, rate or extent of glyoxylate cycle.",positive regulation of glyoxylate cycle,biological_process
95086,GO:2000877,"Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.",negative regulation of oligopeptide transport,biological_process
95087,GO:2000878,"Any process that activates or increases the frequency, rate or extent of oligopeptide transport.",positive regulation of oligopeptide transport,biological_process
95088,GO:2000879,"Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.",negative regulation of dipeptide transport,biological_process
95089,GO:2000880,"Any process that activates or increases the frequency, rate or extent of dipeptide transport.",positive regulation of dipeptide transport,biological_process
95090,GO:2000881,"Any process that modulates the frequency, rate or extent of starch catabolic process.",regulation of starch catabolic process,biological_process
95091,GO:2000882,"Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.",negative regulation of starch catabolic process,biological_process
95092,GO:2000883,"Any process that activates or increases the frequency, rate or extent of starch catabolic process.",positive regulation of starch catabolic process,biological_process
95093,GO:2000884,The chemical reactions and pathways resulting in the breakdown of a glucomannan.,glucomannan catabolic process,biological_process
95094,GO:2000885,The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan.,galactoglucomannan catabolic process,biological_process
95095,GO:2000886,The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan.,glucuronoxylan catabolic process,biological_process
95096,GO:2000887,The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.,glucuronoarabinoxylan catabolic process,biological_process
95097,GO:2000888,The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.,arabinoxylan-containing compound catabolic process,biological_process
95098,GO:2000890,The chemical reactions and pathways resulting in the breakdown of a cellodextrin.,cellodextrin catabolic process,biological_process
95099,GO:2000891,The chemical reactions and pathways involving a cellobiose.,cellobiose metabolic process,biological_process
95100,GO:2000892,The chemical reactions and pathways resulting in the breakdown of a cellobiose.,cellobiose catabolic process,biological_process
95101,GO:2000894,The chemical reactions and pathways resulting in the breakdown of a cellotriose.,cellotriose catabolic process,biological_process
95102,GO:2000895,The chemical reactions and pathways resulting in the breakdown of a hemicellulose.,hemicellulose catabolic process,biological_process
95103,GO:2000896,The chemical reactions and pathways involving an amylopectin.,amylopectin metabolic process,biological_process
95104,GO:2000897,The chemical reactions and pathways resulting in the breakdown of an amylopectin.,amylopectin catabolic process,biological_process
95105,GO:2000898,"Any process that modulates the frequency, rate or extent of glucomannan catabolic process.",regulation of glucomannan catabolic process,biological_process
95106,GO:2000899,The chemical reactions and pathways resulting in the breakdown of a xyloglucan.,xyloglucan catabolic process,biological_process
95107,GO:2000900,The chemical reactions and pathways involving a cyclodextrin.,cyclodextrin metabolic process,biological_process
95108,GO:2000901,The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.,cyclodextrin catabolic process,biological_process
95109,GO:2000902,The chemical reactions and pathways involving a cellooligosaccharide.,cellooligosaccharide metabolic process,biological_process
95110,GO:2000903,The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.,cellooligosaccharide catabolic process,biological_process
95111,GO:2000904,"Any process that modulates the frequency, rate or extent of starch metabolic process.",regulation of starch metabolic process,biological_process
95112,GO:2000907,"Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.",negative regulation of glucomannan catabolic process,biological_process
95113,GO:2000908,"Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.",positive regulation of glucomannan catabolic process,biological_process
95114,GO:2000909,"Any process that modulates the frequency, rate or extent of sterol import.",regulation of sterol import,biological_process
95115,GO:2000910,"Any process that stops, prevents or reduces the frequency, rate or extent of sterol import.",negative regulation of sterol import,biological_process
95116,GO:2000911,"Any process that activates or increases the frequency, rate or extent of sterol import.",positive regulation of sterol import,biological_process
95117,GO:2000912,"Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.",regulation of galactoglucomannan catabolic process,biological_process
95118,GO:2000913,"Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.",negative regulation of galactoglucomannan catabolic process,biological_process
95119,GO:2000914,"Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.",positive regulation of galactoglucomannan catabolic process,biological_process
95120,GO:2000915,"Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.",regulation of glucuronoxylan catabolic process,biological_process
95121,GO:2000916,"Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process.",negative regulation of glucuronoxylan catabolic process,biological_process
95122,GO:2000917,"Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.",positive regulation of glucuronoxylan catabolic process,biological_process
95123,GO:2000918,"Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.",regulation of glucuronoarabinoxylan catabolic process,biological_process
95124,GO:2000919,"Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process.",negative regulation of glucuronoarabinoxylan catabolic process,biological_process
95125,GO:2000920,"Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.",positive regulation of glucuronoarabinoxylan catabolic process,biological_process
95126,GO:2000921,"Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process.",regulation of arabinoxylan-containing compound catabolic process,biological_process
95127,GO:2000922,"Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process.",negative regulation of arabinoxylan-containing compound catabolic process,biological_process
95128,GO:2000923,"Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.",positive regulation of arabinoxylan-containing compound catabolic process,biological_process
95129,GO:2000927,"Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.",regulation of cellodextrin catabolic process,biological_process
95130,GO:2000928,"Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.",negative regulation of cellodextrin catabolic process,biological_process
95131,GO:2000929,"Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.",positive regulation of cellodextrin catabolic process,biological_process
95132,GO:2000936,"Any process that modulates the frequency, rate or extent of cellotriose catabolic process.",regulation of cellotriose catabolic process,biological_process
95133,GO:2000937,"Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process.",negative regulation of cellotriose catabolic process,biological_process
95134,GO:2000938,"Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.",positive regulation of cellotriose catabolic process,biological_process
95135,GO:2000939,"Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.",regulation of plant-type cell wall cellulose catabolic process,biological_process
95136,GO:2000940,"Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.",negative regulation of plant-type cell wall cellulose catabolic process,biological_process
95137,GO:2000941,"Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.",positive regulation of plant-type cell wall cellulose catabolic process,biological_process
95138,GO:2000945,"Any process that modulates the frequency, rate or extent of amylopectin catabolic process.",regulation of amylopectin catabolic process,biological_process
95139,GO:2000946,"Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.",negative regulation of amylopectin catabolic process,biological_process
95140,GO:2000947,"Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.",positive regulation of amylopectin catabolic process,biological_process
95141,GO:2000951,"Any process that modulates the frequency, rate or extent of xyloglucan catabolic process.",regulation of xyloglucan catabolic process,biological_process
95142,GO:2000952,"Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process.",negative regulation of xyloglucan catabolic process,biological_process
95143,GO:2000953,"Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process.",positive regulation of xyloglucan catabolic process,biological_process
95144,GO:2000957,"Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process.",regulation of cyclodextrin catabolic process,biological_process
95145,GO:2000958,"Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process.",negative regulation of cyclodextrin catabolic process,biological_process
95146,GO:2000959,"Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.",positive regulation of cyclodextrin catabolic process,biological_process
95147,GO:2000963,"Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process.",regulation of cellooligosaccharide catabolic process,biological_process
95148,GO:2000964,"Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process.",negative regulation of cellooligosaccharide catabolic process,biological_process
95149,GO:2000965,"Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.",positive regulation of cellooligosaccharide catabolic process,biological_process
95150,GO:2000966,"Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process.",regulation of cell wall polysaccharide catabolic process,biological_process
95151,GO:2000967,"Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.",negative regulation of cell wall polysaccharide catabolic process,biological_process
95152,GO:2000968,"Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.",positive regulation of cell wall polysaccharide catabolic process,biological_process
95153,GO:2000969,"Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.",positive regulation of AMPA receptor activity,biological_process
95154,GO:2000970,"Any process that modulates the frequency, rate or extent of detection of glucose.",regulation of detection of glucose,biological_process
95155,GO:2000971,"Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose.",negative regulation of detection of glucose,biological_process
95156,GO:2000972,"Any process that activates or increases the frequency, rate or extent of detection of glucose.",positive regulation of detection of glucose,biological_process
95157,GO:2000973,"Any process that modulates the frequency, rate or extent of pro-B cell differentiation.",regulation of pro-B cell differentiation,biological_process
95158,GO:2000974,"Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.",negative regulation of pro-B cell differentiation,biological_process
95159,GO:2000975,"Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.",positive regulation of pro-B cell differentiation,biological_process
95160,GO:2000977,"Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.",regulation of forebrain neuron differentiation,biological_process
95161,GO:2000978,"Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.",negative regulation of forebrain neuron differentiation,biological_process
95162,GO:2000979,"Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.",positive regulation of forebrain neuron differentiation,biological_process
95163,GO:2000980,"Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.",regulation of inner ear receptor cell differentiation,biological_process
95164,GO:2000981,"Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.",negative regulation of inner ear receptor cell differentiation,biological_process
95165,GO:2000982,"Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.",positive regulation of inner ear receptor cell differentiation,biological_process
95166,GO:2000983,"Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.",regulation of ATP citrate synthase activity,biological_process
95167,GO:2000986,"Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.",negative regulation of behavioral fear response,biological_process
95168,GO:2000987,"Any process that activates or increases the frequency, rate or extent of behavioral fear response.",positive regulation of behavioral fear response,biological_process
95169,GO:2000988,"Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.",regulation of hemicellulose catabolic process,biological_process
95170,GO:2000989,"Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process.",negative regulation of hemicellulose catabolic process,biological_process
95171,GO:2000990,"Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.",positive regulation of hemicellulose catabolic process,biological_process
95172,GO:2000991,"Any process that modulates the frequency, rate or extent of galactomannan catabolic process.",regulation of galactomannan catabolic process,biological_process
95173,GO:2000992,"Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.",negative regulation of galactomannan catabolic process,biological_process
95174,GO:2000993,"Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.",positive regulation of galactomannan catabolic process,biological_process
95175,GO:2000994,"Any process that modulates the frequency, rate or extent of mannan catabolic process.",regulation of mannan catabolic process,biological_process
95176,GO:2000995,"Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.",negative regulation of mannan catabolic process,biological_process
95177,GO:2000996,"Any process that activates or increases the frequency, rate or extent of mannan catabolic process.",positive regulation of mannan catabolic process,biological_process
95178,GO:2000997,"Any process that modulates the frequency, rate or extent of cellulose catabolic process.",regulation of cellulose catabolic process,biological_process
95179,GO:2000998,"Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.",negative regulation of cellulose catabolic process,biological_process
95180,GO:2000999,"Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.",positive regulation of cellulose catabolic process,biological_process
95181,GO:2001000,"Any process that modulates the frequency, rate or extent of xylan catabolic process.",regulation of xylan catabolic process,biological_process
95182,GO:2001001,"Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.",negative regulation of xylan catabolic process,biological_process
95183,GO:2001002,"Any process that activates or increases the frequency, rate or extent of xylan catabolic process.",positive regulation of xylan catabolic process,biological_process
95184,GO:2001003,"Any process that modulates the frequency, rate or extent of pectin catabolic process.",regulation of pectin catabolic process,biological_process
95185,GO:2001004,"Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.",negative regulation of pectin catabolic process,biological_process
95186,GO:2001005,"Any process that activates or increases the frequency, rate or extent of pectin catabolic process.",positive regulation of pectin catabolic process,biological_process
95187,GO:2001006,"Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.",regulation of cellulose biosynthetic process,biological_process
95188,GO:2001007,"Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.",negative regulation of cellulose biosynthetic process,biological_process
95189,GO:2001008,"Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.",positive regulation of cellulose biosynthetic process,biological_process
95190,GO:2001009,"Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.",regulation of plant-type cell wall cellulose biosynthetic process,biological_process
95191,GO:2001010,"Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.",negative regulation of plant-type cell wall cellulose biosynthetic process,biological_process
95192,GO:2001011,"Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.",positive regulation of plant-type cell wall cellulose biosynthetic process,biological_process
95193,GO:2001013,Any epithelial cell proliferation that is involved in renal tubule morphogenesis.,epithelial cell proliferation involved in renal tubule morphogenesis,biological_process
95194,GO:2001014,"Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.",regulation of skeletal muscle cell differentiation,biological_process
95195,GO:2001015,"Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.",negative regulation of skeletal muscle cell differentiation,biological_process
95196,GO:2001016,"Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.",positive regulation of skeletal muscle cell differentiation,biological_process
95197,GO:2001017,"Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.",regulation of retrograde axon cargo transport,biological_process
95198,GO:2001018,"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.",negative regulation of retrograde axon cargo transport,biological_process
95199,GO:2001019,"Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.",positive regulation of retrograde axon cargo transport,biological_process
95200,GO:2001023,"Any process that modulates the frequency, rate or extent of response to drug.",regulation of response to drug,biological_process
95201,GO:2001024,"Any process that stops, prevents or reduces the frequency, rate or extent of response to drug.",negative regulation of response to drug,biological_process
95202,GO:2001025,"Any process that activates or increases the frequency, rate or extent of response to drug.",positive regulation of response to drug,biological_process
95203,GO:2001026,"Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.",regulation of endothelial cell chemotaxis,biological_process
95204,GO:2001027,"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.",negative regulation of endothelial cell chemotaxis,biological_process
95205,GO:2001028,"Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.",positive regulation of endothelial cell chemotaxis,biological_process
95206,GO:2001032,"Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.",regulation of double-strand break repair via nonhomologous end joining,biological_process
95207,GO:2001033,"Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.",negative regulation of double-strand break repair via nonhomologous end joining,biological_process
95208,GO:2001034,"Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.",positive regulation of double-strand break repair via nonhomologous end joining,biological_process
95209,GO:2001035,"Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.",regulation of tongue muscle cell differentiation,biological_process
95210,GO:2001036,"Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.",negative regulation of tongue muscle cell differentiation,biological_process
95211,GO:2001037,"Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.",positive regulation of tongue muscle cell differentiation,biological_process
95212,GO:2001038,"Any process that modulates the frequency, rate or extent of cellular response to drug.",regulation of cellular response to drug,biological_process
95213,GO:2001039,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug.",negative regulation of cellular response to drug,biological_process
95214,GO:2001040,"Any process that activates or increases the frequency, rate or extent of cellular response to drug.",positive regulation of cellular response to drug,biological_process
95215,GO:2001042,"Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.",negative regulation of septum digestion after cytokinesis,biological_process
95216,GO:2001043,"Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.",positive regulation of septum digestion after cytokinesis,biological_process
95217,GO:2001044,"Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.",regulation of integrin-mediated signaling pathway,biological_process
95218,GO:2001045,"Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.",negative regulation of integrin-mediated signaling pathway,biological_process
95219,GO:2001046,"Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.",positive regulation of integrin-mediated signaling pathway,biological_process
95220,GO:2001049,"Any process that modulates the frequency, rate or extent of tendon cell differentiation.",regulation of tendon cell differentiation,biological_process
95221,GO:2001050,"Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.",negative regulation of tendon cell differentiation,biological_process
95222,GO:2001051,"Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.",positive regulation of tendon cell differentiation,biological_process
95223,GO:2001053,"Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.",regulation of mesenchymal cell apoptotic process,biological_process
95224,GO:2001054,"Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.",negative regulation of mesenchymal cell apoptotic process,biological_process
95225,GO:2001055,"Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.",positive regulation of mesenchymal cell apoptotic process,biological_process
95226,GO:2001057,The chemical reactions and pathways involving a reactive nitrogen species.,reactive nitrogen species metabolic process,biological_process
95227,GO:2001059,The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.,D-tagatose 6-phosphate catabolic process,biological_process
95228,GO:2001060,The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.,D-glycero-D-manno-heptose 7-phosphate metabolic process,biological_process
95229,GO:2001061,The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate.,D-glycero-D-manno-heptose 7-phosphate biosynthetic process,biological_process
95230,GO:2001062,Binding to xylan.,xylan binding,molecular_function
95231,GO:2001063,Binding to glucomannan.,glucomannan binding,molecular_function
95232,GO:2001064,Binding to cellooligosaccharide.,cellooligosaccharide binding,molecular_function
95233,GO:2001065,Binding to mannan.,mannan binding,molecular_function
95234,GO:2001066,Binding to amylopectin.,amylopectin binding,molecular_function
95235,GO:2001067,Binding to pullulan.,pullulan binding,molecular_function
95236,GO:2001068,Binding to arabinoxylan.,arabinoxylan binding,molecular_function
95237,GO:2001069,Binding to glycogen.,glycogen binding,molecular_function
95238,GO:2001070,Binding to starch.,starch binding,molecular_function
95239,GO:2001071,Binding to maltoheptaose.,maltoheptaose binding,molecular_function
95240,GO:2001072,Binding to galactomannan.,galactomannan binding,molecular_function
95241,GO:2001073,Binding to cyclodextrin.,cyclodextrin binding,molecular_function
95242,GO:2001074,"Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.",regulation of metanephric ureteric bud development,biological_process
95243,GO:2001075,"Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.",negative regulation of metanephric ureteric bud development,biological_process
95244,GO:2001076,"Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.",positive regulation of metanephric ureteric bud development,biological_process
95245,GO:2001077,"Binding to (1->3),(1->4)-beta-glucan.","(1->3),(1->4)-beta-glucan binding",molecular_function
95246,GO:2001078,Binding to (1->6)-beta-D-glucan.,(1->6)-beta-D-glucan binding,molecular_function
95247,GO:2001079,Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.,beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding,molecular_function
95248,GO:2001080,Binding to chitosan.,chitosan binding,molecular_function
95249,GO:2001081,Binding to (1->4)-beta-D-galactan.,(1->4)-beta-D-galactan binding,molecular_function
95250,GO:2001082,Binding to inulin.,inulin binding,molecular_function
95251,GO:2001083,Binding to alpha-D-glucan.,alpha-D-glucan binding,molecular_function
95252,GO:2001084,Binding to L-arabinofuranose.,L-arabinofuranose binding,molecular_function
95253,GO:2001085,Binding to arabinogalactan.,arabinogalactan binding,molecular_function
95254,GO:2001087,"The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",sophorose transport,biological_process
95255,GO:2001088,"The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",trisaccharide transport,biological_process
95256,GO:2001089,"The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltotriose transport,biological_process
95257,GO:2001090,"The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltotriulose transport,biological_process
95258,GO:2001091,"The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nigerotriose transport,biological_process
95259,GO:2001092,"The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",arabinotriose transport,biological_process
95260,GO:2001093,"The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",galactotriose transport,biological_process
95261,GO:2001094,"The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",xylotriose transport,biological_process
95262,GO:2001095,"The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",mannotriose transport,biological_process
95263,GO:2001096,"The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",cellotriose transport,biological_process
95264,GO:2001097,"The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",laminaritriose transport,biological_process
95265,GO:2001098,"The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",tetrasaccharide transport,biological_process
95266,GO:2001099,"The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltotetraose transport,biological_process
95267,GO:2001100,"The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",pentasaccharide transport,biological_process
95268,GO:2001101,"The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltopentaose transport,biological_process
95269,GO:2001102,"The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",hexasaccharide transport,biological_process
95270,GO:2001103,"The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltohexaose transport,biological_process
95271,GO:2001104,"The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",heptasaccharide transport,biological_process
95272,GO:2001105,"The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",maltoheptaose transport,biological_process
95273,GO:2001107,"Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.",negative regulation of Rho guanyl-nucleotide exchange factor activity,biological_process
95274,GO:2001109,"Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.",regulation of lens epithelial cell proliferation,biological_process
95275,GO:2001110,"Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.",negative regulation of lens epithelial cell proliferation,biological_process
95276,GO:2001111,"Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.",positive regulation of lens epithelial cell proliferation,biological_process
95277,GO:2001112,"Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.",regulation of cellular response to hepatocyte growth factor stimulus,biological_process
95278,GO:2001113,"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.",negative regulation of cellular response to hepatocyte growth factor stimulus,biological_process
95279,GO:2001114,"Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.",positive regulation of cellular response to hepatocyte growth factor stimulus,biological_process
95280,GO:2001116,The chemical reactions and pathways resulting in the formation of a methanopterin.,methanopterin-containing compound biosynthetic process,biological_process
95281,GO:2001118,The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.,tetrahydromethanopterin biosynthetic process,biological_process
95282,GO:2001119,The chemical reactions and pathways involving a methanofuran.,methanofuran metabolic process,biological_process
95283,GO:2001120,The chemical reactions and pathways resulting in the formation of a methanofuran.,methanofuran biosynthetic process,biological_process
95284,GO:2001121,The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.,coenzyme gamma-F420-2 biosynthetic process,biological_process
95285,GO:2001123,The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.,maltoheptaose catabolic process,biological_process
95286,GO:2001124,"Any process that modulates the frequency, rate or extent of translational frameshifting.",regulation of translational frameshifting,biological_process
95287,GO:2001125,"Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.",negative regulation of translational frameshifting,biological_process
95288,GO:2001126,"Any process that activates or increases the frequency, rate or extent of translational frameshifting.",positive regulation of translational frameshifting,biological_process
95289,GO:2001135,"Any process that modulates the frequency, rate or extent of endocytic recycling.",regulation of endocytic recycling,biological_process
95290,GO:2001136,"Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling.",negative regulation of endocytic recycling,biological_process
95291,GO:2001137,"Any process that activates or increases the frequency, rate or extent of endocytic recycling.",positive regulation of endocytic recycling,biological_process
95292,GO:2001138,"Any process that modulates the frequency, rate or extent of phospholipid transport.",regulation of phospholipid transport,biological_process
95293,GO:2001139,"Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.",negative regulation of phospholipid transport,biological_process
95294,GO:2001140,"Any process that activates or increases the frequency, rate or extent of phospholipid transport.",positive regulation of phospholipid transport,biological_process
95295,GO:2001141,"Any process that modulates the frequency, rate or extent of RNA biosynthetic process.",regulation of RNA biosynthetic process,biological_process
95296,GO:2001142,"The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",nicotinate transport,biological_process
95297,GO:2001143,"The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",N-methylnicotinate transport,biological_process
95298,GO:2001145,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.","negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity",biological_process
95299,GO:2001147,Binding to camalexin.,camalexin binding,molecular_function
95300,GO:2001148,"Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport.",regulation of dipeptide transmembrane transport,biological_process
95301,GO:2001149,"Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport.",negative regulation of dipeptide transmembrane transport,biological_process
95302,GO:2001150,"Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.",positive regulation of dipeptide transmembrane transport,biological_process
95303,GO:2001151,"Any process that modulates the frequency, rate or extent of renal water transport.",regulation of renal water transport,biological_process
95304,GO:2001152,"Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.",negative regulation of renal water transport,biological_process
95305,GO:2001153,"Any process that activates or increases the frequency, rate or extent of renal water transport.",positive regulation of renal water transport,biological_process
95306,GO:2001154,"Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.",regulation of glycolytic fermentation to ethanol,biological_process
95307,GO:2001155,"Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.",negative regulation of glycolytic fermentation to ethanol,biological_process
95308,GO:2001156,"Any process that modulates the frequency, rate or extent of L-proline catabolic process.",regulation of L-proline catabolic process,biological_process
95309,GO:2001157,"Any process that stops, prevents or reduces the frequency, rate or extent of L-proline catabolic process.",negative regulation of L-proline catabolic process,biological_process
95310,GO:2001158,"Any process that activates or increases the frequency, rate or extent of L-proline catabolic process.",positive regulation of L-proline catabolic process,biological_process
95311,GO:2001159,"Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.",regulation of protein localization by the Cvt pathway,biological_process
95312,GO:2001169,"Any process that modulates the frequency, rate or extent of ATP biosynthetic process.",regulation of ATP biosynthetic process,biological_process
95313,GO:2001170,"Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.",negative regulation of ATP biosynthetic process,biological_process
95314,GO:2001171,"Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.",positive regulation of ATP biosynthetic process,biological_process
95315,GO:2001172,"Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.",positive regulation of glycolytic fermentation to ethanol,biological_process
95316,GO:2001176,"Any process that modulates the frequency, rate or extent of mediator complex assembly.",regulation of mediator complex assembly,biological_process
95317,GO:2001177,"Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.",negative regulation of mediator complex assembly,biological_process
95318,GO:2001178,"Any process that activates or increases the frequency, rate or extent of mediator complex assembly.",positive regulation of mediator complex assembly,biological_process
95319,GO:2001185,"Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.","regulation of CD8-positive, alpha-beta T cell activation",biological_process
95320,GO:2001186,"Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.","negative regulation of CD8-positive, alpha-beta T cell activation",biological_process
95321,GO:2001187,"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.","positive regulation of CD8-positive, alpha-beta T cell activation",biological_process
95322,GO:2001188,"Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.",regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,biological_process
95323,GO:2001189,"Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.",negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,biological_process
95324,GO:2001190,"Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.",positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,biological_process
95325,GO:2001196,"Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.",positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine,biological_process
95326,GO:2001197,Any basement membrane assembly that is involved in embryonic body morphogenesis.,basement membrane assembly involved in embryonic body morphogenesis,biological_process
95327,GO:2001198,"Any process that modulates the frequency, rate or extent of dendritic cell differentiation.",regulation of dendritic cell differentiation,biological_process
95328,GO:2001199,"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.",negative regulation of dendritic cell differentiation,biological_process
95329,GO:2001200,"Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.",positive regulation of dendritic cell differentiation,biological_process
95330,GO:2001204,"Any process that modulates the frequency, rate or extent of osteoclast development.",regulation of osteoclast development,biological_process
95331,GO:2001205,"Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.",negative regulation of osteoclast development,biological_process
95332,GO:2001206,"Any process that activates or increases the frequency, rate or extent of osteoclast development.",positive regulation of osteoclast development,biological_process
95333,GO:2001207,"Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.",regulation of transcription elongation by RNA polymerase I,biological_process
95334,GO:2001208,"Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.",negative regulation of transcription elongation by RNA polymerase I,biological_process
95335,GO:2001209,"Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.",positive regulation of transcription elongation by RNA polymerase I,biological_process
95336,GO:2001210,"Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.","regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway",biological_process
95337,GO:2001211,"Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.","negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway",biological_process
95338,GO:2001212,"Any process that modulates the frequency, rate or extent of vasculogenesis.",regulation of vasculogenesis,biological_process
95339,GO:2001213,"Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.",negative regulation of vasculogenesis,biological_process
95340,GO:2001214,"Any process that activates or increases the frequency, rate or extent of vasculogenesis.",positive regulation of vasculogenesis,biological_process
95341,GO:2001222,"Any process that modulates the frequency, rate or extent of neuron migration.",regulation of neuron migration,biological_process
95342,GO:2001223,"Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.",negative regulation of neuron migration,biological_process
95343,GO:2001224,"Any process that activates or increases the frequency, rate or extent of neuron migration.",positive regulation of neuron migration,biological_process
95344,GO:2001225,"Any process that modulates the frequency, rate or extent of chloride transport.",regulation of chloride transport,biological_process
95345,GO:2001226,"Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.",negative regulation of chloride transport,biological_process
95346,GO:2001227,Binding to quercitrin.,quercitrin binding,molecular_function
95347,GO:2001228,"Any process that modulates the frequency, rate or extent of response to gamma radiation.",regulation of response to gamma radiation,biological_process
95348,GO:2001229,"Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.",negative regulation of response to gamma radiation,biological_process
95349,GO:2001230,"Any process that activates or increases the frequency, rate or extent of response to gamma radiation.",positive regulation of response to gamma radiation,biological_process
95350,GO:2001231,"Any process that modulates the frequency, rate or extent of protein localization to prospore membrane.",regulation of protein localization to prospore membrane,biological_process
95351,GO:2001232,"Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane.",positive regulation of protein localization to prospore membrane,biological_process
95352,GO:2001233,"Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.",regulation of apoptotic signaling pathway,biological_process
95353,GO:2001234,"Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.",negative regulation of apoptotic signaling pathway,biological_process
95354,GO:2001235,"Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.",positive regulation of apoptotic signaling pathway,biological_process
95355,GO:2001236,"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.",regulation of extrinsic apoptotic signaling pathway,biological_process
95356,GO:2001237,"Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.",negative regulation of extrinsic apoptotic signaling pathway,biological_process
95357,GO:2001238,"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.",positive regulation of extrinsic apoptotic signaling pathway,biological_process
95358,GO:2001239,"Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.",regulation of extrinsic apoptotic signaling pathway in absence of ligand,biological_process
95359,GO:2001240,"Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.",negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,biological_process
95360,GO:2001241,"Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.",positive regulation of extrinsic apoptotic signaling pathway in absence of ligand,biological_process
95361,GO:2001242,"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.",regulation of intrinsic apoptotic signaling pathway,biological_process
95362,GO:2001243,"Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.",negative regulation of intrinsic apoptotic signaling pathway,biological_process
95363,GO:2001244,"Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.",positive regulation of intrinsic apoptotic signaling pathway,biological_process
95364,GO:2001245,"Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process.",regulation of phosphatidylcholine biosynthetic process,biological_process
95365,GO:2001246,"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.",negative regulation of phosphatidylcholine biosynthetic process,biological_process
95366,GO:2001247,"Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.",positive regulation of phosphatidylcholine biosynthetic process,biological_process
95367,GO:2001248,"Any process that modulates the frequency, rate or extent of ammonia assimilation cycle.",regulation of ammonia assimilation cycle,biological_process
95368,GO:2001249,"Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle.",negative regulation of ammonia assimilation cycle,biological_process
95369,GO:2001250,"Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.",positive regulation of ammonia assimilation cycle,biological_process
95370,GO:2001251,"Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.",negative regulation of chromosome organization,biological_process
95371,GO:2001252,"Any process that activates or increases the frequency, rate or extent of chromosome organization.",positive regulation of chromosome organization,biological_process
95372,GO:2001256,"Any process that modulates the frequency, rate or extent of store-operated calcium entry.",regulation of store-operated calcium entry,biological_process
95373,GO:2001259,"Any process that activates or increases the frequency, rate or extent of cation channel activity.",positive regulation of cation channel activity,biological_process
95374,GO:2001260,"Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway.",regulation of semaphorin-plexin signaling pathway,biological_process
95375,GO:2001261,"Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.",negative regulation of semaphorin-plexin signaling pathway,biological_process
95376,GO:2001262,"Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.",positive regulation of semaphorin-plexin signaling pathway,biological_process
95377,GO:2001276,"Any process that modulates the frequency, rate or extent of L-leucine biosynthetic process.",regulation of L-leucine biosynthetic process,biological_process
95378,GO:2001277,"Any process that stops, prevents or reduces the frequency, rate or extent of L-leucine biosynthetic process.",negative regulation of L-leucine biosynthetic process,biological_process
95379,GO:2001278,"Any process that activates or increases the frequency, rate or extent of L-leucine biosynthetic process.",positive regulation of L-leucine biosynthetic process,biological_process
95380,GO:2001279,"Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process.",regulation of unsaturated fatty acid biosynthetic process,biological_process
95381,GO:2001280,"Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.",positive regulation of unsaturated fatty acid biosynthetic process,biological_process
95382,GO:2001281,"Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.",regulation of muscle cell chemotaxis toward tendon cell,biological_process
95383,GO:2001282,"Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.",negative regulation of muscle cell chemotaxis toward tendon cell,biological_process
95384,GO:2001284,"Any process that modulates the frequency, rate or extent of BMP secretion.",regulation of BMP secretion,biological_process
95385,GO:2001285,"Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.",negative regulation of BMP secretion,biological_process
95386,GO:2001286,"Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.",regulation of caveolin-mediated endocytosis,biological_process
95387,GO:2001287,"Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.",negative regulation of caveolin-mediated endocytosis,biological_process
95388,GO:2001288,"Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.",positive regulation of caveolin-mediated endocytosis,biological_process
95389,GO:2001289,"The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.",lipid X metabolic process,biological_process
95390,GO:2001291,"The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.",codeine metabolic process,biological_process
95391,GO:2001292,"The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.",codeine catabolic process,biological_process
95392,GO:2001293,"The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.",malonyl-CoA metabolic process,biological_process
95393,GO:2001294,"The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A.",malonyl-CoA catabolic process,biological_process
95394,GO:2001295,"The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.",malonyl-CoA biosynthetic process,biological_process
95395,GO:2001301,The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid.,lipoxin biosynthetic process,biological_process
95396,GO:2001302,"The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.",lipoxin A4 metabolic process,biological_process
95397,GO:2001303,"The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.",lipoxin A4 biosynthetic process,biological_process
95398,GO:2001304,"The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.",lipoxin B4 metabolic process,biological_process
95399,GO:2001306,"The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.",lipoxin B4 biosynthetic process,biological_process
95400,GO:2001307,The chemical reactions and pathways resulting in the formation of a xanthone-containing compound.,xanthone-containing compound biosynthetic process,biological_process
95401,GO:2001309,"The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.",gliotoxin catabolic process,biological_process
95402,GO:2001310,"The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.",gliotoxin biosynthetic process,biological_process
95403,GO:2001311,The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.,lysobisphosphatidic acid metabolic process,biological_process
95404,GO:2001312,The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.,lysobisphosphatidic acid biosynthetic process,biological_process
95405,GO:2001315,The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.,UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process,biological_process
95406,GO:2001317,The chemical reactions and pathways resulting in the formation of kojic acid.,kojic acid biosynthetic process,biological_process
95407,GO:7770001,An inner mitochondrial protein carrier capable of transporting pyruvate into the mitochondrion.,mitochondrial pyruvate carrier complex,cellular_component
95408,GO:7770002,Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + NH4+(out) + Cl-(out) = Na+(in) + NH4+(in) + Cl-(in).,sodium:ammonium:chloride symporter activity,molecular_function
95409,GO:7770003,Catalysis of the reaction: an L-alpha-amino acid + cholate = an N-choloyl-L-alpha-amino acid + H2O.,amino acid conjugated cholate hydrolase activity,molecular_function
95410,GO:7770004,Catalysis of the reaction: cholate + L-serine = L-serocholate + H2O.,L-serine conjugated cholate hydrolase activity,molecular_function
95411,GO:7770005,Catalysis of the reaction: cholate + L-alanine = L-alanocholate + H2O.,L-alanine conjugated cholate hydrolase activity,molecular_function
95412,GO:7770006,Catalysis of the reaction: cholate + L-phenylalanine = L-phenylalanocholate + H2O.,L-phenylalanine conjugated cholate hydrolase activity,molecular_function
95413,GO:7770007,Catalysis of the reaction: cholate + L-arginine = L-arginocholate + H2O.,L-arginine conjugated cholate hydrolase activity,molecular_function
95414,GO:7770008,Catalysis of the reaction: cholate + L-histidine = L-histidocholate + H2O.,L-histidine conjugated cholate hydrolase activity,molecular_function
95415,GO:7770009,Catalysis of the reaction: cholate + L-tryptophan = L-tryptophocholate + H2O.,L-tryptophan conjugated cholate hydrolase activity,molecular_function
95416,GO:7770010,A protein complex consisting of GTP binding protein 3 (GTPBP3) and mitochondrial tRNA translation optimization 1 (MTO1). The complex catalyzes the formation of 5-taurinomethyluridine at wobble position U34 of mitochondrial tRNAs.,GTPBP3-MTO1 complex,cellular_component
95417,GO:7770011,"Enables the transfer of a specific lipid molecule from one membrane to another, coupled with the simultaneous counter-transfer of a different lipid molecule in the opposite direction.",lipid exchange activity,molecular_function
95418,GO:7770012,"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of starch.",negative regulation of starch biosynthetic process,biological_process
95419,GO:7770013,"A protein complex that acts as a receptor for the neuroprotective peptide humanin (HN). In humans the receptor complex is a trimer composed of CNTFR, IL6ST and IL27RA. HN binding to IL27RA and CNTFR induces oligomerization of the three subunits.",humanin receptor complex,cellular_component
95420,GO:7770014,The process in which spermatids lose their mitochondrial nucleoids during spermatid development. This process involves the controlled elimination of mitochondrial DNA-protein complexes while preserving the mitochondrial membranes and and contributes to maternal mitochondrial inheritance patterns by inhibiting paternal transmission.,spermatid mitochondrial nucleoid elimination,biological_process
95421,GO:7770015,"A protein complex that mediates the transport of lipids between membranes, in which a lipid molecule or molecules is transferred through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.",intermembrane lipid transporter complex,cellular_component
95422,GO:7770016,"A process of mitochondrial translational elongation that takes place when a mitochondrial ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.",rescue of stalled mitochondrial ribosome,biological_process
95423,GO:7770017,"A cellular process which results in an increase in the size (surface area) of the plasma membrane during cell growth or osmotic stress. This can occur by lipid transfer, membrane trafficking, or eisosome disassembly.",plasma membrane expansion,biological_process
95424,GO:7770018,"Any process that activates or increases the frequency, rate or extent of plasma membrane expansion.",positive regulation of plasma membrane expansion,biological_process
95425,GO:7770019,"Any process that stops, prevents or reduces the frequency, rate or extent of enteroendocrine cell differentiation.",negative regulation of enteroendocrine cell differentiation,biological_process
95426,GO:7770020,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal enterochromaffin enteroendocrine cell. Enterochromaffin enteroendocrine cells are found in the gastrointestinal mucosa and secrete serotonin and some neurotransmitters including enkephalins and substance P.,intestinal enterochromaffin enteroendocrine cell differentiation,biological_process
95427,GO:7770021,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type G enteroendocrine cell. Intestinal type G enteroendocrine cells are found in the stomach and duodenum and are responsible for the secretion of gastrin and enkephalin.,intestinal type G enteroendocrine cell differentiation,biological_process
95428,GO:7770022,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type I enteroendocrine cell. Intestinal type I enteroendocrine cells are found in the duodenum and jejunum and secrete cholecystokinin.,intestinal type I enteroendocrine cell differentiation,biological_process
95429,GO:7770023,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type L enteroendocrine cell. Intestinal type L enteroendocrine cells are found in ileum and large intestine and secrete glucagon-like peptides.,intestinal type L enteroendocrine cell differentiation,biological_process
95430,GO:7770024,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type N enteroendocrine cell. Intestinal type N enteroendocrine cells are found in the ileum and jejunum and secrete neurotensin.,intestinal type N enteroendocrine cell differentiation,biological_process
95431,GO:7770025,The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an intestinal type D enteroendocrine cell. Intestinal type D enteroendocrine cells are found in the gastrointestinal tract and in the pancreas and secrete somatostatin.,intestinal type D enteroendocrine cell differentiation,biological_process
95432,GO:7770026,"Enables the transfer of N(6),N(6),N(6)-trimethyl-L-lysine from one side of a membrane to the other.","N(6),N(6),N(6)-trimethyl-L-lysine transmembrane transporter activity",molecular_function
95433,GO:7770027,Enables the transfer of dimethylarginine from one side of a membrane to the other.,dimethylarginine transmembrane transporter activity,molecular_function
95434,GO:7770029,Combining with phosphatidylserine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.,phosphatidylserine receptor activity,molecular_function
95435,GO:7770030,"A heterotetrameric cGMP phosphodiesterase complex found in the disc membranes of rod photoreceptor outer segments. It consists of two catalytic subunits, PDE6A and PDE6B, and two inhibitory gamma-subunits, PDE6G. In response to activation by transducin, the complex hydrolyzes cyclic GMP, thereby mediating the light-induced closure of cGMP-gated ion channels during rod phototransduction.",rod photoreceptor phosphodiesterase 6 complex,cellular_component
95436,GO:7770031,Binding to a sodium ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.,sodium ion sequestering activity,molecular_function
95437,GO:7770033,"The directed movement of octopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Octopamine is a monoamine neurotransmitter occurring predominantly in invertebrates.",octopamine transport,biological_process
95438,GO:7770034,"The chemical reactions and pathways resulting in the formation of nickel-pincer nucleotide (NPN) cofactor, also known as nickel pyridinium-3,5-bisthiocarboxylic acid mononucleotide.",nickel-pincer nucleotide cofactor biosynthetic process,biological_process
95439,GO:7770035,"Any process that stops, prevents or reduces the frequency, rate or extent of ER to Golgi vesicle-mediated transport.",negative regulation of ER to Golgi vesicle-mediated transport,biological_process
95440,GO:7770036,Catalysis of the reaction: L-threonyl-[protein] + FAD = FMN-L-threonyl-[protein] + AMP + H+.,flavin transferase activity,molecular_function
95441,GO:7770037,"The process by which central nervous system glial and associated cells assemble and stabilize a dense, organized glial border at the site of injury. This involves proliferation and reorganization of reactive astrocytes and NG2 glia (oligodendrocyte precursor cells), deposition of extracellular matrix components, and formation of a barrier that modulates inflammation and regeneration.",glial scar formation,biological_process
95442,GO:7770038,"Any process that reduces the pH of the melanosomal lumen, corresponding to an increase in hydrogen ion concentration.",melanosomal lumen acidification,biological_process
95443,GO:7770039,"Any process that increases the pH of the melanosomal lumen, corresponding to a decrease in hydrogen ion concentration.",melanosomal lumen pH elevation,biological_process
95444,GO:7770040,"The outermost lipid bilayer surrounding complex plastids in organisms that acquired their plastids through secondary endosymbiosis. This membrane is derived from the host cell's endomembrane system and is continuous with the rough endoplasmic reticulum and the outer nuclear envelope. In some species, the cytoplasmic face may be studded with ribosomes.",epiplastidial membrane,cellular_component
95445,GO:7770041,The lipid bilayer that forms the second outermost membrane of complex plastids in organisms that acquired their plastids through secondary endosymbiosis. The periplastidial membrane is evolutionarily derived from the plasma membrane of the engulfed algal endosymbiont and together with the outer envelope membrane of the plastid defines the periplastidial compartment.,periplastidial membrane,cellular_component
95446,GO:7770042,A membrane-associated protein complex found in archaea that consists of sugar binding proteins assembled via a type IV pilin-like assembly system. The complex is located at the cell surface and functions in sugar uptake by facilitating the interaction between solute binding proteins and ABC transporters. The complex forms high molecular mass structures (400-600 kDa) that are integrated within or closely associated with the S-layer.,bindosome complex,cellular_component
95447,GO:7770043,"Binding to a lipid and delivering it to an acceptor protein, including enzymes, nuclear receptors, and other lipid-binding proteins. The lipid may be presented while bound to the chaperone for enzymatic modification or signaling, or fully transferred to the acceptor protein.",lipid chaperone activity,molecular_function
95448,GO:7770044,Catalysis of the reaction: biliverdin IXalpha + 2 reduced ferredoxin + 4 H+ = (3Z)-phycoerythrobilin + 2 oxidized ferredoxin.,phycoerythrobilin synthase activity,molecular_function
95449,GO:7770045,"Any process that stops, prevents, or reduces the frequency, rate or extent of GCN2-mediated signaling.",negative regulation of GCN2-mediated signaling,biological_process
95450,GO:7770051,An organelle membrane contact site between the mitochondrial outer membrane and the lysosomal membrane.,mitochondrial-lysosomal membrane contact site,cellular_component
95451,GO:7770052,An organelle membrane contact site between the endoplasmic reticulum membrane and the lysosomal membrane.,endoplasmic reticulum-lysosome membrane contact site,cellular_component
95452,GO:7770053,"A protein complex that contains one or more nucleotide-binding leucine-rich repeat (NLR) proteins and functions as an intracellular innate immune receptor. Upon activation by pathogen effectors or danger signals, the complex oligomerizes with adaptor and effector proteins to trigger downstream immune responses including programmed cell death.",nucleotide-binding leucine-rich repeat receptor complex,cellular_component
95453,GO:7770054,Catalysis of the reaction: S-adenosyl-L-methionine + adenosine(37) in tRNA(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenosine(37) in tRNA(Val) + H+.,tRNA(Val) (adenine(37)-N6)-methyltransferase activity,molecular_function
95454,GO:7770055,"Any process that reduces the pH of the intestinal lumen, corresponding to an increase in hydrogen ion concentration.",intestinal lumen acidification,biological_process
95455,GO:7770056,"Any process that reduces the pH of an extracellular fluid of a multicellular organism, corresponding to an increase in hydrogen ion concentration.",multicellular organismal-level extracellular fluid acidification,biological_process
95456,GO:7770057,The directed import of copper cation from the cytosol across the Golgi membrane into the Golgi lumen.,copper ion import into Golgi lumen,biological_process
95457,GO:7770058,The import of proteins from the cytosol to their final destination in the mitochondria.,mitochondrial protein import pathway,biological_process
95458,GO:7770059,The import of alpha helical and tail-anchored proteins from the cytosol and their insertion into the mitochondrial outer membrane.,alpha helical protein insertion into mitochondrial outer membrane,biological_process
95459,GO:7770060,The import of proteins from the cytosol across the outer mitochondrial membrane and laterally inserted into the inner membrane. Typically acting on single-pass transmembrane proteins with an N-terminal targeting sequence and an internal hydrophobic stop-transfer sequence which targets them for lateral insertion.,TOM-TIM23-SORT-mediated protein insertion into the mitochondrial inner membrane,biological_process
95460,GO:7770061,"The import of multipass-membrane proteins from the cytosol and their insertion into the mitochondrial inner membrane, supported by tiny-tim chaperones.",TOM-TIM22-mediated mitochondrial inner membrane protein insertion,biological_process
95461,GO:7770062,A membrane-membrane adaptor activity that provides the first point of contact and physically bridges the vesicle membrane and its target membrane prior to vesicle docking and fusion.,vesicle membrane tethering activity,molecular_function
95462,GO:7770063,The import of beta barrel proteins from the cytosol and their insertion into the mitochondrial outer membrane.,beta barrel protein insertion into mitochondrial outer membrane,biological_process
95463,GO:7770064,"An adaptor activity that brings together two actin filaments, enabling the bundling or networking of actin filaments (F-actin).",actin-filament cross-linking activity,molecular_function
95464,GO:7770065,"The binding activity of a molecule that brings together the peroxisome membrane and the chloroplast membrane, establishing the localization of the peroxisome close to the chloroplast.",peroxisome-chloroplast membrane tether activity,molecular_function
95465,GO:7770066,"The binding activity of a molecule that brings together an endoplasmic reticulum membrane and a vacuole membrane either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites.",endoplasmic reticulum-vacuole tether activity,molecular_function
95466,GO:7770067,"The binding activity of a molecule that brings together the contractile vacuolar membrane and the plasma membrane, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the contractile vacuole at a specific plasma membrane discharge site.",contractile vacuole-plasma membrane tether activity,molecular_function
95467,GO:7770068,Catalysis of the reaction: 2 Fe2+ + NADP+ + H+ = 2 Fe3+ + NADPH.,ferric iron reductase activity,molecular_function
95468,GO:7770069,The selective degradation of ferritin to release iron by macroautophagy.,ferritinophagy,biological_process
95469,GO:7770070,"A conserved, hetero-oligomeric (often tetrameric) cycling ER-Golgi protein complex that selectively recruits secretory cargo, especially GPI-anchored proteins, into COPII vesicles and helps maintain early secretory pathway organization. A functional p24 complex typically contains one member of each subfamily of p24 proteins, alpha, beta, gamma and delta.",p24 cargo receptor complex,cellular_component
95470,GO:7770071,A process by which an organism causes inflammatory response in another organism via the action of a venom.,venom-mediated activation of inflammatory response,biological_process
95471,GO:7770072,Combining with a double-stranded RNA and transmitting the signal to initiate an innate immune response.,double-stranded RNA immune receptor activity,molecular_function
95472,GO:7770073,Combining with a left-handed Z-RNA and transmitting the signal to initiate an innate immune response. Z-RNA is a left-handed double-helical conformation of RNA in which the phosphate backbone zigzags.,left-handed Z-RNA immune receptor activity,molecular_function
95473,GO:7770074,"A glycoprotein biosynthetic process in which a single N-acetylglucosamine is covalently linked via a beta-glycosidic bond to the oxygen atom of a serine or threonine side chain in a protein, resulting in the formation of a protein O-linked glycan. The sugar is not elongated into a larger oligosaccharide chain.",protein O-linked glycosylation via N-acetylglucosamine,biological_process
95474,GO:7770075,A venom-mediated activation of inflammatory response that triggers leukocyte migration in another organism.,venom-mediated leukocyte migration,biological_process
95475,GO:7770076,A venom-mediated activation of inflammatory response that triggers release of an inflammatory mediator in another organism. Inflammatory mediators include cytokines or interleukins.,venom-mediated release of inflammatory mediator,biological_process
95476,GO:7770077,"Any process that stops, prevents or reduces the frequency, rate or extent of PKR/eIFalpha signaling.",negative regulation of PKR/eIFalpha signaling,biological_process
95477,GO:7770079,"Any process that activates or increases the frequency, rate or extent of cytogamy.",positive regulation of cytogamy,biological_process
95478,GO:7770080,Catalysis of the reaction: questin hydroquinone + NADP+ = questin + NADPH + 2 H+.,questin reductase (NADPH) activity,molecular_function
95479,GO:7770081,Catalysis of the reaction: questin hydroquinone + O2 = demethylsulochrin + 2 H+.,questin hydroquinone dioxygenase activity,molecular_function
95480,GO:7770082,"A beta-N-acetylhexosaminidase complex composed of an alpha subunit and a beta subunit. In humans the subunits are encoded by HEXA and HEXB. In association with the GM2 activator protein, the complex degrades GM2 ganglioside within the lysosome.",beta-hexosaminidase A complex,cellular_component
95481,GO:7770083,"An endocytosis process in which plasma membrane cargo is internalized through endophilin-enriched, clathrin-uncoated invaginations.",fast endophilin-mediated endocytosis,biological_process
95482,GO:7770084,An endocytosis process in which clathrin-uncoated carriers (CLICs) internalize plasma membrane cargo and deliver it to GPI-enriched early endosomal compartments (GEECs).,CLIC/GEEC-mediated endocytosis,biological_process
95483,GO:7770085,"A protein complex which is capable of protocatechuate 3,4-dioxygenase activity. It consists of an alpha subunit (PcaG) and a beta subunit (PcaH), with the non-heme iron active site formed at the alpha-beta interface.","protocatechuate 3,4-dioxygenase complex",cellular_component
95484,GO:7770086,"Catalysis of the reaction: trans-resveratrol + O2 = 3,5-dihydroxybenzaldehyde + 4-hydroxybenzaldehyde.",resveratrol dioxygenase activity,molecular_function
95485,GO:7770087,Binds to and increases the activity of a sodium channel.,sodium channel activator activity,molecular_function
95486,GO:7770088,"A membrane contact site between the endoplasmic reticulum membrane and the membrane of an organelle of the endolysosomal system, such as an endosome or lysosome.",endoplasmic reticulum-endolysosomal membrane contact site,cellular_component