---
license: cc-by-4.0
pretty_name: ichorbio Biosimilar Reference Database
tags:
- biology
- proteins
- antibodies
- biosimilars
- bioinformatics
- developability
size_categories:
- n<1K
---

# ichorbio Biosimilar Reference Database — v0.1.3

[![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.23350140.svg)](https://doi.org/10.5281/zenodo.23350140)

Open, citable developability & biophysical data for ichorbio's research-grade biosimilars.
Structured per the Developer Brief (Antibodies / Samples / Methods / Measurements; one row per value).

## What is in v0.1.3 (seed release)
- **480 antibodies** — identity, target + UniProt, isotype/format, heavy + light chain
  sequences (from IMGT/mAb-DB), ichorbio SKU, product URL and RRID where assigned.
- **960 theoretical measurements** — molecular weight and theoretical pI, computed from the
  sequence (marked as theoretical, not laboratory values).
- **SEC-HPLC purity for 82 biosimilars** from supplier Certificates of Analysis — 68 as the
  exact monomer % read from the CoA chromatogram peak table (280 nm main peak), the rest at a
  >95% specification where no chromatogram is provided.

## Added as the supplier's assays arrive (no rebuild needed)
Further developability data — Tm (DSF), HIC, AC-SINS, PSR, and more SEC-HPLC lots — plus
raw assay traces. Each new assay is added as rows in `measurements.csv`, never as new columns.

## Files
`antibodies.csv` · `samples.csv` · `methods.csv` · `measurements.csv` · `summary_wide.csv` ·
`data_dictionary.csv` · `sequences.fasta` · `ichorbio_bsr.json` · `dataset.jsonld` ·
`CITATION.cff` · `LICENSE.txt` · `llms.txt` · `CHANGELOG.md`

## Source & versions
- GitHub (source repository): https://github.com/ichorbio/biosimilar-reference-database
- Zenodo (archived, citable): https://doi.org/10.5281/zenodo.23350140

## How to cite
ichorbio (2026). ichorbio Biosimilar Reference Database (version 0.1.3) [Data set].
Zenodo. https://doi.org/10.5281/zenodo.23350140

## Licence
CC BY 4.0. Data may be reused, including commercially, with attribution to ichorbio.