diff --git a/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_analyze.log b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_analyze.log new file mode 100644 index 0000000000000000000000000000000000000000..2258edacf86ddf102b6aea7b5e20937d565d0fee --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_analyze.log @@ -0,0 +1,662 @@ + arm state thin gen obs_thinned obs_native_n gen_pct obs_pct gen_over_obs spearman_donors + zs_K1000 C1Q-high monocyte (reference) 0.424 76 / 45,219 5,976 / 111,269 6788 0.168 5.371 0.031 0.021 + zs_K1000 Cycling T/NK 0.424 269 / 55,050 2,235 / 345,949 3461 0.489 0.646 0.756 0.026 + zs_K1000 Cycling activated T (CD38/HLA-DR) 0.445 162 / 43,708 3,240 / 298,117 5877 0.371 1.087 0.341 -0.051 + zs_K1000 Proliferating T (label) 1.000 1,353 / 43,708 4,793 / 298,117 4793 3.096 1.608 1.925 -0.076 + zs_K1000 Plasmablast (label) 1.000 700 / 123,000 8,423 / 589,478 8423 0.569 1.429 0.398 0.367 + zs_K1000 Plasmablast (markers) 0.498 914 / 123,000 15,398 / 589,478 26774 0.743 2.612 0.284 0.343 + zs_K1000 MS1 monocyte (IL1R2+) 0.424 376 / 45,219 12,436 / 111,269 18712 0.832 11.177 0.074 0.436 + zs_K1000 Cycling monocyte (Ye 2026) 0.424 85 / 45,219 2,620 / 111,269 4601 0.188 2.355 0.080 0.201 + zs_K1000 ISG-high monocyte (positive control) 0.424 8,021 / 45,219 11,117 / 111,269 21377 17.738 9.991 1.775 0.505 + zs_K1000 ISG-high T 0.445 1,226 / 43,708 4,636 / 298,117 10685 2.805 1.555 1.804 0.574 + zs_K1000 DN2 / ABC B 0.579 659 / 18,509 2,606 / 99,729 4309 3.560 2.613 1.363 0.112 + zs_K1000 HSPC 0.498 74 / 123,000 633 / 589,478 741 0.060 0.107 0.560 0.221 + zs_K1000 Cytotoxic CD4 T 0.611 65 / 15,727 1,716 / 140,213 2091 0.413 1.224 0.338 0.316 + zs_K1000 Granulocyte-like (LDG) 0.498 309 / 123,000 6,679 / 589,478 14337 0.251 1.133 0.222 0.428 + zs_K1000 Platelet signal in monocytes (negative control) 0.424 1,282 / 45,219 11,651 / 111,269 23329 2.835 10.471 0.271 0.309 + xcalL_K1000 C1Q-high monocyte (reference) 0.800 145 / 32,509 6,563 / 111,269 6788 0.446 5.898 0.076 0.124 + xcalL_K1000 Cycling T/NK 0.770 294 / 69,445 3,058 / 345,949 3461 0.423 0.884 0.479 0.228 + xcalL_K1000 Cycling activated T (CD38/HLA-DR) 0.779 240 / 57,674 4,940 / 298,117 5877 0.416 1.657 0.251 0.044 + xcalL_K1000 Proliferating T (label) 1.000 596 / 57,674 4,793 / 298,117 4793 1.033 1.608 0.643 0.051 + xcalL_K1000 Plasmablast (label) 1.000 1,376 / 123,000 8,423 / 589,478 8423 1.119 1.429 0.783 0.405 + xcalL_K1000 Plasmablast (markers) 0.828 1,776 / 123,000 22,866 / 589,478 26774 1.444 3.879 0.372 0.480 + xcalL_K1000 MS1 monocyte (IL1R2+) 0.800 3,626 / 32,509 17,109 / 111,269 18712 11.154 15.376 0.725 0.640 + xcalL_K1000 Cycling monocyte (Ye 2026) 0.800 301 / 32,509 4,019 / 111,269 4601 0.926 3.612 0.256 0.272 + xcalL_K1000 ISG-high monocyte (positive control) 0.800 7,537 / 32,509 18,288 / 111,269 21377 23.184 16.436 1.411 0.506 + xcalL_K1000 ISG-high T 0.779 2,478 / 57,674 8,312 / 298,117 10685 4.297 2.788 1.541 0.442 + xcalL_K1000 DN2 / ABC B 0.984 212 / 17,496 4,248 / 99,729 4309 1.212 4.260 0.284 -0.039 + xcalL_K1000 HSPC 0.828 268 / 123,000 712 / 589,478 741 0.218 0.121 1.804 0.151 + xcalL_K1000 Cytotoxic CD4 T 0.920 455 / 15,517 2,031 / 140,213 2091 2.932 1.449 2.024 0.546 + xcalL_K1000 Granulocyte-like (LDG) 0.828 165 / 123,000 11,798 / 589,478 14337 0.134 2.001 0.067 0.400 + xcalL_K1000 Platelet signal in monocytes (negative control) 0.800 1,059 / 32,509 19,665 / 111,269 23329 3.258 17.673 0.184 0.244 + locoL_lora16sat_s26750_K1000 C1Q-high monocyte (reference) 0.398 45 / 22,525 5,864 / 111,269 6788 0.200 5.270 0.038 0.053 + locoL_lora16sat_s26750_K1000 Cycling T/NK 0.577 66 / 66,365 2,597 / 345,949 3461 0.099 0.751 0.132 -0.124 + locoL_lora16sat_s26750_K1000 Cycling activated T (CD38/HLA-DR) 0.601 66 / 51,582 4,119 / 298,117 5877 0.128 1.382 0.093 0.022 + locoL_lora16sat_s26750_K1000 Proliferating T (label) 1.000 671 / 51,582 4,793 / 298,117 4793 1.301 1.608 0.809 -0.014 + locoL_lora16sat_s26750_K1000 Plasmablast (label) 1.000 2,419 / 123,000 8,423 / 589,478 8423 1.967 1.429 1.376 0.352 + locoL_lora16sat_s26750_K1000 Plasmablast (markers) 0.577 2,816 / 123,000 17,142 / 589,478 26774 2.289 2.908 0.787 0.491 + locoL_lora16sat_s26750_K1000 MS1 monocyte (IL1R2+) 0.398 300 / 22,525 12,001 / 111,269 18712 1.332 10.786 0.123 0.490 + locoL_lora16sat_s26750_K1000 Cycling monocyte (Ye 2026) 0.398 38 / 22,525 2,564 / 111,269 4601 0.169 2.304 0.073 0.137 + locoL_lora16sat_s26750_K1000 ISG-high monocyte (positive control) 0.398 2,802 / 22,525 10,592 / 111,269 21377 12.440 9.519 1.307 0.493 + locoL_lora16sat_s26750_K1000 ISG-high T 0.601 1,884 / 51,582 6,365 / 298,117 10685 3.652 2.135 1.711 0.586 + locoL_lora16sat_s26750_K1000 DN2 / ABC B 0.647 123 / 28,854 2,941 / 99,729 4309 0.426 2.949 0.145 0.023 + locoL_lora16sat_s26750_K1000 HSPC 0.577 225 / 123,000 658 / 589,478 741 0.183 0.112 1.639 0.140 + locoL_lora16sat_s26750_K1000 Cytotoxic CD4 T 0.690 352 / 18,440 1,832 / 140,213 2091 1.909 1.307 1.461 0.657 + locoL_lora16sat_s26750_K1000 Granulocyte-like (LDG) 0.577 28 / 123,000 7,948 / 589,478 14337 0.023 1.348 0.017 0.093 + locoL_lora16sat_s26750_K1000 Platelet signal in monocytes (negative control) 0.398 436 / 22,525 11,056 / 111,269 23329 1.936 9.936 0.195 0.099 + locoL_lora64sat_s59000_K1000 C1Q-high monocyte (reference) 0.375 62 / 20,095 5,805 / 111,269 6788 0.309 5.217 0.059 0.041 + locoL_lora64sat_s59000_K1000 Cycling T/NK 0.516 87 / 62,854 2,485 / 345,949 3461 0.138 0.718 0.193 -0.134 + locoL_lora64sat_s59000_K1000 Cycling activated T (CD38/HLA-DR) 0.538 81 / 47,076 3,729 / 298,117 5877 0.172 1.251 0.138 -0.108 + locoL_lora64sat_s59000_K1000 Proliferating T (label) 1.000 788 / 47,076 4,793 / 298,117 4793 1.674 1.608 1.041 0.086 + locoL_lora64sat_s59000_K1000 Plasmablast (label) 1.000 1,780 / 123,000 8,423 / 589,478 8423 1.447 1.429 1.013 0.379 + locoL_lora64sat_s59000_K1000 Plasmablast (markers) 0.514 2,217 / 123,000 15,679 / 589,478 26774 1.802 2.660 0.678 0.469 + locoL_lora64sat_s59000_K1000 MS1 monocyte (IL1R2+) 0.375 264 / 20,095 11,483 / 111,269 18712 1.314 10.320 0.127 0.434 + locoL_lora64sat_s59000_K1000 Cycling monocyte (Ye 2026) 0.375 28 / 20,095 2,414 / 111,269 4601 0.139 2.170 0.064 0.230 + locoL_lora64sat_s59000_K1000 ISG-high monocyte (positive control) 0.375 2,599 / 20,095 10,052 / 111,269 21377 12.934 9.034 1.432 0.426 + locoL_lora64sat_s59000_K1000 ISG-high T 0.538 1,689 / 47,076 5,549 / 298,117 10685 3.588 1.861 1.928 0.591 + locoL_lora64sat_s59000_K1000 DN2 / ABC B 0.542 165 / 33,738 2,471 / 99,729 4309 0.489 2.478 0.197 0.065 + locoL_lora64sat_s59000_K1000 HSPC 0.514 373 / 123,000 621 / 589,478 741 0.303 0.105 2.879 0.118 + locoL_lora64sat_s59000_K1000 Cytotoxic CD4 T 0.620 376 / 17,846 1,751 / 140,213 2091 2.107 1.249 1.687 0.616 + locoL_lora64sat_s59000_K1000 Granulocyte-like (LDG) 0.514 23 / 123,000 6,865 / 589,478 14337 0.019 1.165 0.016 0.253 + locoL_lora64sat_s59000_K1000 Platelet signal in monocytes (negative control) 0.375 323 / 20,095 10,439 / 111,269 23329 1.607 9.382 0.171 0.450 + locoL_fullsat_s108500_K1000 C1Q-high monocyte (reference) 0.368 84 / 19,498 5,733 / 111,269 6788 0.431 5.152 0.084 -0.136 + locoL_fullsat_s108500_K1000 Cycling T/NK 0.546 170 / 64,295 2,540 / 345,949 3461 0.264 0.734 0.360 -0.054 + locoL_fullsat_s108500_K1000 Cycling activated T (CD38/HLA-DR) 0.579 163 / 47,582 3,947 / 298,117 5877 0.343 1.324 0.259 0.063 + locoL_fullsat_s108500_K1000 Proliferating T (label) 1.000 848 / 47,582 4,793 / 298,117 4793 1.782 1.608 1.108 -0.010 + locoL_fullsat_s108500_K1000 Plasmablast (label) 1.000 3,876 / 123,000 8,423 / 589,478 8423 3.151 1.429 2.205 0.225 + locoL_fullsat_s108500_K1000 Plasmablast (markers) 0.536 4,997 / 123,000 16,148 / 589,478 26774 4.063 2.739 1.483 0.367 + locoL_fullsat_s108500_K1000 MS1 monocyte (IL1R2+) 0.368 541 / 19,498 11,349 / 111,269 18712 2.775 10.200 0.272 0.475 + locoL_fullsat_s108500_K1000 Cycling monocyte (Ye 2026) 0.368 51 / 19,498 2,394 / 111,269 4601 0.262 2.152 0.122 0.381 + locoL_fullsat_s108500_K1000 ISG-high monocyte (positive control) 0.368 3,039 / 19,498 9,916 / 111,269 21377 15.586 8.912 1.749 0.459 + locoL_fullsat_s108500_K1000 ISG-high T 0.579 1,953 / 47,582 6,180 / 298,117 10685 4.104 2.073 1.980 0.446 + locoL_fullsat_s108500_K1000 DN2 / ABC B 0.566 247 / 33,860 2,545 / 99,729 4309 0.729 2.552 0.286 0.361 + locoL_fullsat_s108500_K1000 HSPC 0.536 396 / 123,000 630 / 589,478 741 0.322 0.107 3.012 0.022 + locoL_fullsat_s108500_K1000 Cytotoxic CD4 T 0.692 344 / 15,735 1,831 / 140,213 2091 2.186 1.306 1.674 0.616 + locoL_fullsat_s108500_K1000 Granulocyte-like (LDG) 0.536 17 / 123,000 7,216 / 589,478 14337 0.014 1.224 0.011 0.180 + locoL_fullsat_s108500_K1000 Platelet signal in monocytes (negative control) 0.368 686 / 19,498 10,365 / 111,269 23329 3.518 9.315 0.378 0.135 + locoL_scratchsat_s50000_K1000 C1Q-high monocyte (reference) 0.465 119 / 22,398 6,056 / 111,269 6788 0.531 5.443 0.098 0.284 + locoL_scratchsat_s50000_K1000 Cycling T/NK 0.560 53 / 74,248 2,593 / 345,949 3461 0.071 0.750 0.095 -0.081 + locoL_scratchsat_s50000_K1000 Cycling activated T (CD38/HLA-DR) 0.602 104 / 55,023 4,041 / 298,117 5877 0.189 1.356 0.139 -0.063 + locoL_scratchsat_s50000_K1000 Proliferating T (label) 1.000 387 / 55,023 4,793 / 298,117 4793 0.703 1.608 0.437 0.010 + locoL_scratchsat_s50000_K1000 Plasmablast (label) 1.000 855 / 123,000 8,423 / 589,478 8423 0.695 1.429 0.486 0.376 + locoL_scratchsat_s50000_K1000 Plasmablast (markers) 0.572 1,483 / 123,000 17,056 / 589,478 26774 1.206 2.893 0.417 0.454 + locoL_scratchsat_s50000_K1000 MS1 monocyte (IL1R2+) 0.465 594 / 22,398 13,227 / 111,269 18712 2.652 11.887 0.223 0.496 + locoL_scratchsat_s50000_K1000 Cycling monocyte (Ye 2026) 0.465 38 / 22,398 2,846 / 111,269 4601 0.170 2.558 0.066 0.070 + locoL_scratchsat_s50000_K1000 ISG-high monocyte (positive control) 0.465 2,286 / 22,398 12,081 / 111,269 21377 10.206 10.857 0.940 0.372 + locoL_scratchsat_s50000_K1000 ISG-high T 0.602 1,353 / 55,023 6,364 / 298,117 10685 2.459 2.135 1.152 0.402 + locoL_scratchsat_s50000_K1000 DN2 / ABC B 0.632 165 / 22,928 2,845 / 99,729 4309 0.720 2.853 0.252 -0.025 + locoL_scratchsat_s50000_K1000 HSPC 0.572 152 / 123,000 647 / 589,478 741 0.124 0.110 1.126 0.234 + locoL_scratchsat_s50000_K1000 Cytotoxic CD4 T 0.682 281 / 21,101 1,833 / 140,213 2091 1.332 1.307 1.019 0.348 + locoL_scratchsat_s50000_K1000 Granulocyte-like (LDG) 0.572 96 / 123,000 7,751 / 589,478 14337 0.078 1.315 0.059 0.283 + locoL_scratchsat_s50000_K1000 Platelet signal in monocytes (negative control) 0.465 631 / 22,398 12,640 / 111,269 23329 2.817 11.360 0.248 0.182 +locoL_scratchsat_s100000_K1000 C1Q-high monocyte (reference) 0.420 125 / 22,887 5,909 / 111,269 6788 0.546 5.311 0.103 0.220 +locoL_scratchsat_s100000_K1000 Cycling T/NK 0.528 83 / 70,681 2,463 / 345,949 3461 0.117 0.712 0.165 0.034 +locoL_scratchsat_s100000_K1000 Cycling activated T (CD38/HLA-DR) 0.557 121 / 53,015 3,837 / 298,117 5877 0.228 1.287 0.177 0.165 +locoL_scratchsat_s100000_K1000 Proliferating T (label) 1.000 464 / 53,015 4,793 / 298,117 4793 0.875 1.608 0.544 -0.003 +locoL_scratchsat_s100000_K1000 Plasmablast (label) 1.000 1,186 / 123,000 8,423 / 589,478 8423 0.964 1.429 0.675 0.301 +locoL_scratchsat_s100000_K1000 Plasmablast (markers) 0.536 1,713 / 123,000 16,040 / 589,478 26774 1.393 2.721 0.512 0.430 +locoL_scratchsat_s100000_K1000 MS1 monocyte (IL1R2+) 0.420 418 / 22,887 12,403 / 111,269 18712 1.826 11.147 0.164 0.419 +locoL_scratchsat_s100000_K1000 Cycling monocyte (Ye 2026) 0.420 26 / 22,887 2,563 / 111,269 4601 0.114 2.303 0.049 0.212 +locoL_scratchsat_s100000_K1000 ISG-high monocyte (positive control) 0.420 1,926 / 22,887 11,113 / 111,269 21377 8.415 9.988 0.843 0.406 +locoL_scratchsat_s100000_K1000 ISG-high T 0.557 1,056 / 53,015 5,906 / 298,117 10685 1.992 1.981 1.005 0.311 +locoL_scratchsat_s100000_K1000 DN2 / ABC B 0.582 173 / 24,575 2,653 / 99,729 4309 0.704 2.660 0.265 -0.076 +locoL_scratchsat_s100000_K1000 HSPC 0.536 407 / 123,000 659 / 589,478 741 0.331 0.112 2.960 0.102 +locoL_scratchsat_s100000_K1000 Cytotoxic CD4 T 0.648 294 / 20,325 1,789 / 140,213 2091 1.446 1.276 1.134 0.394 +locoL_scratchsat_s100000_K1000 Granulocyte-like (LDG) 0.536 36 / 123,000 7,285 / 589,478 14337 0.029 1.236 0.024 0.243 +locoL_scratchsat_s100000_K1000 Platelet signal in monocytes (negative control) 0.420 573 / 22,887 11,616 / 111,269 23329 2.504 10.440 0.240 0.048 +locoL_scratchsat_s150000_K1000 C1Q-high monocyte (reference) 0.422 92 / 24,712 5,925 / 111,269 6788 0.372 5.325 0.070 0.197 +locoL_scratchsat_s150000_K1000 Cycling T/NK 0.529 49 / 68,025 2,519 / 345,949 3461 0.072 0.728 0.099 -0.061 +locoL_scratchsat_s150000_K1000 Cycling activated T (CD38/HLA-DR) 0.550 75 / 51,724 3,774 / 298,117 5877 0.145 1.266 0.115 0.071 +locoL_scratchsat_s150000_K1000 Proliferating T (label) 1.000 470 / 51,724 4,793 / 298,117 4793 0.909 1.608 0.565 0.109 +locoL_scratchsat_s150000_K1000 Plasmablast (label) 1.000 1,393 / 123,000 8,423 / 589,478 8423 1.133 1.429 0.793 0.292 +locoL_scratchsat_s150000_K1000 Plasmablast (markers) 0.532 1,834 / 123,000 16,182 / 589,478 26774 1.491 2.745 0.543 0.439 +locoL_scratchsat_s150000_K1000 MS1 monocyte (IL1R2+) 0.422 423 / 24,712 12,379 / 111,269 18712 1.712 11.125 0.154 0.529 +locoL_scratchsat_s150000_K1000 Cycling monocyte (Ye 2026) 0.422 23 / 24,712 2,643 / 111,269 4601 0.093 2.375 0.039 0.001 +locoL_scratchsat_s150000_K1000 ISG-high monocyte (positive control) 0.422 2,382 / 24,712 11,092 / 111,269 21377 9.639 9.969 0.967 0.357 +locoL_scratchsat_s150000_K1000 ISG-high T 0.550 1,090 / 51,724 5,770 / 298,117 10685 2.107 1.935 1.089 0.401 +locoL_scratchsat_s150000_K1000 DN2 / ABC B 0.556 200 / 26,390 2,483 / 99,729 4309 0.758 2.490 0.304 0.103 +locoL_scratchsat_s150000_K1000 HSPC 0.532 184 / 123,000 641 / 589,478 741 0.150 0.109 1.376 0.250 +locoL_scratchsat_s150000_K1000 Cytotoxic CD4 T 0.611 281 / 19,157 1,733 / 140,213 2091 1.467 1.236 1.187 0.455 +locoL_scratchsat_s150000_K1000 Granulocyte-like (LDG) 0.532 51 / 123,000 7,154 / 589,478 14337 0.041 1.214 0.034 0.351 +locoL_scratchsat_s150000_K1000 Platelet signal in monocytes (negative control) 0.422 427 / 24,712 11,567 / 111,269 23329 1.728 10.396 0.166 0.171 +locoL_scratchsat_s162000_K1000 C1Q-high monocyte (reference) 0.400 80 / 20,817 5,852 / 111,269 6788 0.384 5.259 0.073 0.335 +locoL_scratchsat_s162000_K1000 Cycling T/NK 0.532 39 / 72,031 2,487 / 345,949 3461 0.054 0.719 0.075 -0.048 +locoL_scratchsat_s162000_K1000 Cycling activated T (CD38/HLA-DR) 0.552 54 / 55,355 3,759 / 298,117 5877 0.098 1.261 0.077 0.117 +locoL_scratchsat_s162000_K1000 Proliferating T (label) 1.000 478 / 55,355 4,793 / 298,117 4793 0.864 1.608 0.537 0.098 +locoL_scratchsat_s162000_K1000 Plasmablast (label) 1.000 1,534 / 123,000 8,423 / 589,478 8423 1.247 1.429 0.873 0.314 +locoL_scratchsat_s162000_K1000 Plasmablast (markers) 0.529 1,923 / 123,000 16,017 / 589,478 26774 1.563 2.717 0.575 0.449 +locoL_scratchsat_s162000_K1000 MS1 monocyte (IL1R2+) 0.400 363 / 20,817 12,047 / 111,269 18712 1.744 10.827 0.161 0.538 +locoL_scratchsat_s162000_K1000 Cycling monocyte (Ye 2026) 0.400 17 / 20,817 2,514 / 111,269 4601 0.082 2.259 0.036 0.260 +locoL_scratchsat_s162000_K1000 ISG-high monocyte (positive control) 0.400 1,881 / 20,817 10,666 / 111,269 21377 9.036 9.586 0.943 0.325 +locoL_scratchsat_s162000_K1000 ISG-high T 0.552 1,176 / 55,355 5,751 / 298,117 10685 2.124 1.929 1.101 0.333 +locoL_scratchsat_s162000_K1000 DN2 / ABC B 0.563 178 / 26,637 2,507 / 99,729 4309 0.668 2.514 0.266 0.060 +locoL_scratchsat_s162000_K1000 HSPC 0.529 222 / 123,000 640 / 589,478 741 0.180 0.109 1.662 0.250 +locoL_scratchsat_s162000_K1000 Cytotoxic CD4 T 0.610 329 / 20,524 1,755 / 140,213 2091 1.603 1.252 1.281 0.393 +locoL_scratchsat_s162000_K1000 Granulocyte-like (LDG) 0.529 31 / 123,000 7,163 / 589,478 14337 0.025 1.215 0.021 0.297 +locoL_scratchsat_s162000_K1000 Platelet signal in monocytes (negative control) 0.400 339 / 20,817 11,095 / 111,269 23329 1.628 9.971 0.163 -0.009 + within_lora_n5__raw C1Q-high monocyte (reference) 0.821 668 / 21,215 6,620 / 111,269 6788 3.149 5.950 0.529 0.180 + within_lora_n5__raw Cycling T/NK 0.928 193 / 76,263 3,317 / 345,949 3461 0.253 0.959 0.264 0.181 + within_lora_n5__raw Cycling activated T (CD38/HLA-DR) 0.913 211 / 71,107 5,514 / 298,117 5877 0.297 1.850 0.160 0.129 + within_lora_n5__raw Proliferating T (label) 1.000 696 / 71,107 4,793 / 298,117 4793 0.979 1.608 0.609 0.143 + within_lora_n5__raw Plasmablast (label) 1.000 705 / 123,000 8,423 / 589,478 8423 0.573 1.429 0.401 0.137 + within_lora_n5__raw Plasmablast (markers) 0.907 995 / 123,000 24,665 / 589,478 26774 0.809 4.184 0.193 0.303 + within_lora_n5__raw MS1 monocyte (IL1R2+) 0.821 2,171 / 21,215 17,461 / 111,269 18712 10.233 15.693 0.652 0.449 + within_lora_n5__raw Cycling monocyte (Ye 2026) 0.821 230 / 21,215 4,052 / 111,269 4601 1.084 3.642 0.298 0.127 + within_lora_n5__raw ISG-high monocyte (positive control) 0.821 1,944 / 21,215 18,743 / 111,269 21377 9.163 16.845 0.544 0.390 + within_lora_n5__raw ISG-high T 0.913 896 / 71,107 9,772 / 298,117 10685 1.260 3.278 0.384 0.531 + within_lora_n5__raw DN2 / ABC B 0.913 355 / 21,374 4,019 / 99,729 4309 1.661 4.030 0.412 -0.007 + within_lora_n5__raw HSPC 0.907 115 / 123,000 715 / 589,478 741 0.093 0.121 0.771 0.030 + within_lora_n5__raw Cytotoxic CD4 T 0.949 533 / 33,262 2,047 / 140,213 2091 1.602 1.460 1.098 0.562 + within_lora_n5__raw Granulocyte-like (LDG) 0.907 108 / 123,000 12,984 / 589,478 14337 0.088 2.203 0.040 0.257 + within_lora_n5__raw Platelet signal in monocytes (negative control) 0.821 2,207 / 21,215 20,172 / 111,269 23329 10.403 18.129 0.574 0.248 + within_real_lora__raw C1Q-high monocyte (reference) 0.823 687 / 22,735 6,596 / 111,269 6788 3.022 5.928 0.510 0.357 + within_real_lora__raw Cycling T/NK 0.999 396 / 75,575 3,459 / 345,949 3461 0.524 1.000 0.524 0.320 + within_real_lora__raw Cycling activated T (CD38/HLA-DR) 0.995 399 / 67,851 5,857 / 298,117 5877 0.588 1.965 0.299 0.227 + within_real_lora__raw Proliferating T (label) 1.000 861 / 67,851 4,793 / 298,117 4793 1.269 1.608 0.789 0.377 + within_real_lora__raw Plasmablast (label) 1.000 1,327 / 123,000 8,423 / 589,478 8423 1.079 1.429 0.755 0.197 + within_real_lora__raw Plasmablast (markers) 0.956 1,783 / 123,000 25,772 / 589,478 26774 1.450 4.372 0.332 0.453 + within_real_lora__raw MS1 monocyte (IL1R2+) 0.823 2,535 / 22,735 17,346 / 111,269 18712 11.150 15.589 0.715 0.566 + within_real_lora__raw Cycling monocyte (Ye 2026) 0.823 197 / 22,735 4,078 / 111,269 4601 0.867 3.665 0.236 0.146 + within_real_lora__raw ISG-high monocyte (positive control) 0.823 2,299 / 22,735 18,659 / 111,269 21377 10.112 16.769 0.603 0.600 + within_real_lora__raw ISG-high T 0.995 1,405 / 67,851 10,648 / 298,117 10685 2.071 3.572 0.580 0.750 + within_real_lora__raw DN2 / ABC B 0.932 233 / 19,900 4,081 / 99,729 4309 1.171 4.092 0.286 0.335 + within_real_lora__raw HSPC 0.956 80 / 123,000 735 / 589,478 741 0.065 0.125 0.522 0.076 + within_real_lora__raw Cytotoxic CD4 T 1.000 609 / 30,144 2,091 / 140,213 2091 2.020 1.491 1.355 0.708 + within_real_lora__raw Granulocyte-like (LDG) 0.956 174 / 123,000 13,612 / 589,478 14337 0.141 2.309 0.061 0.306 + within_real_lora__raw Platelet signal in monocytes (negative control) 0.823 2,241 / 22,735 20,136 / 111,269 23329 9.857 18.097 0.545 0.146 + arm state contrast n_a n_b obs_a obs_b gen_a gen_b obs_diff gen_diff same_direction + zs_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3317 / 57131 110 / 8702 51 / 30249 3 / 2246 5.51 0.03 True + zs_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2129 / 15430 29 / 4363 12 / 5951 0 / 852 8.12 0.16 True + zs_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5446 / 72561 530 / 38708 63 / 36200 13 / 9019 6.05 0.02 True + zs_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 819 / 187719 101 / 44192 157 / 27944 19 / 6966 0.35 0.40 True + zs_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 545 / 43733 249 / 24170 63 / 10516 2 / 3561 0.12 0.57 True + zs_K1000 Cycling T/NK all sepsis vs all controls 61 21 1364 / 231452 871 / 114497 220 / 38460 49 / 16590 -0.10 0.29 False + zs_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1272 / 162485 191 / 33194 98 / 21026 11 / 5961 0.41 0.44 True + zs_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 657 / 40153 382 / 20916 34 / 8662 1 / 3199 -0.35 0.38 False + zs_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 1929 / 202638 1311 / 95479 132 / 29688 30 / 14020 -0.35 0.25 False + zs_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 758 / 21026 77 / 5961 -0.06 2.50 False + zs_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 371 / 8662 41 / 3199 -0.18 3.07 False + zs_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 1129 / 29688 224 / 14020 -0.62 2.11 False + zs_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 374 / 69000 1 / 10500 0.97 0.53 True + zs_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 291 / 22500 9 / 6000 -0.14 1.14 False + zs_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 665 / 91500 35 / 31500 0.29 0.62 True + zs_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6545 / 310451 411 / 59344 483 / 69000 11 / 10500 1.32 0.60 True + zs_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4454 / 98395 2040 / 35572 335 / 22500 25 / 6000 -1.51 1.07 False + zs_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 10999 / 408846 4399 / 180632 818 / 91500 96 / 31500 -0.07 0.59 False + zs_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 8085 / 57131 16 / 8702 302 / 30249 2 / 2246 13.08 0.69 True + zs_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1906 / 15430 0 / 4363 51 / 5951 2 / 852 14.43 0.38 True + zs_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9991 / 72561 2445 / 38708 353 / 36200 23 / 9019 8.08 0.57 True + zs_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1132 / 57131 54 / 8702 63 / 30249 2 / 2246 1.13 0.14 True + zs_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1165 / 15430 29 / 4363 14 / 5951 1 / 852 5.28 0.11 True + zs_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2297 / 72561 323 / 38708 77 / 36200 8 / 9019 2.01 0.15 True + zs_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4941 / 57131 630 / 8702 5208 / 30249 139 / 2246 3.77 11.68 True + zs_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3679 / 15430 916 / 4363 1884 / 5951 270 / 852 -6.78 -1.89 True + zs_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 8620 / 72561 2497 / 38708 7092 / 36200 929 / 9019 2.37 7.50 True + zs_K1000 ISG-high T adult sepsis vs adult HC 46 7 963 / 162485 148 / 33194 411 / 21026 26 / 5961 0.83 1.16 True + zs_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 995 / 40153 2217 / 20916 354 / 8662 386 / 3199 -12.61 -7.53 True + zs_K1000 ISG-high T all sepsis vs all controls 61 21 1958 / 202638 2678 / 95479 765 / 29688 461 / 14020 -1.75 -0.53 True + zs_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1153 / 47206 165 / 4301 369 / 8076 28 / 1117 0.06 2.11 True + zs_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 819 / 33660 171 / 4954 129 / 5257 31 / 1499 -0.41 0.92 False + zs_K1000 DN2 / ABC B all sepsis vs all controls 61 21 1972 / 80866 634 / 18863 498 / 13333 161 / 5176 0.38 1.20 True + zs_K1000 HSPC adult sepsis vs adult HC 46 7 341 / 310451 56 / 59344 40 / 69000 2 / 10500 0.01 0.04 True + zs_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 136 / 98395 21 / 35572 21 / 22500 0 / 6000 0.08 0.09 True + zs_K1000 HSPC all sepsis vs all controls 61 21 477 / 408846 156 / 180632 61 / 91500 13 / 31500 0.03 0.03 True + zs_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1042 / 83070 344 / 13845 31 / 6949 13 / 1451 -1.21 -0.23 True + zs_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 59 / 17697 28 / 8125 7 / 3645 8 / 1496 -0.05 -0.27 True + zs_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1101 / 100767 615 / 39446 38 / 10594 27 / 5133 -1.03 0.04 False + zs_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4194 / 310451 451 / 59344 215 / 69000 21 / 10500 0.88 0.11 True + zs_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1025 / 98395 117 / 35572 39 / 22500 4 / 6000 0.78 0.11 True + zs_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5219 / 408846 1460 / 180632 254 / 91500 55 / 31500 0.56 0.10 True + zs_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6737 / 57131 621 / 8702 981 / 30249 19 / 2246 3.20 2.13 True + zs_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1721 / 15430 178 / 4363 151 / 5951 13 / 852 2.92 0.49 True + zs_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 8458 / 72561 3193 / 38708 1132 / 36200 150 / 9019 2.19 1.25 True + xcalL_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3664 / 57131 136 / 8702 103 / 22482 2 / 983 6.04 0.10 True + xcalL_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2281 / 15430 37 / 4363 18 / 4358 1 / 354 9.23 0.10 True + xcalL_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5945 / 72561 618 / 38708 121 / 26840 24 / 5669 6.80 -0.09 False + xcalL_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 1083 / 187719 130 / 44192 191 / 37419 8 / 9014 0.46 0.52 True + xcalL_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 721 / 43733 374 / 24170 57 / 11107 6 / 4024 -0.02 0.42 False + xcalL_K1000 Cycling T/NK all sepsis vs all controls 61 21 1804 / 231452 1254 / 114497 248 / 48526 46 / 20919 -0.25 0.29 False + xcalL_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 2011 / 162485 330 / 33194 156 / 29747 6 / 7891 0.49 0.55 True + xcalL_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 888 / 40153 606 / 20916 47 / 9745 5 / 3710 -0.97 0.36 False + xcalL_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2899 / 202638 2041 / 95479 203 / 39492 37 / 18182 -0.70 0.29 False + xcalL_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 350 / 29747 24 / 7891 -0.06 0.96 False + xcalL_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 168 / 9745 15 / 3710 -0.18 1.19 False + xcalL_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 518 / 39492 78 / 18182 -0.62 0.85 False + xcalL_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 841 / 69000 2 / 10500 0.97 1.20 True + xcalL_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 466 / 22500 24 / 6000 -0.14 1.67 False + xcalL_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1307 / 91500 69 / 31500 0.29 1.21 True + xcalL_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 9858 / 310451 783 / 59344 1061 / 69000 9 / 10500 1.67 1.45 True + xcalL_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 6557 / 98395 2767 / 35572 586 / 22500 44 / 6000 -1.50 1.87 False + xcalL_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 16415 / 408846 6451 / 180632 1647 / 91500 129 / 31500 -0.04 1.39 False + xcalL_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 11056 / 57131 45 / 8702 2715 / 22482 1 / 983 17.40 8.97 True + xcalL_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 2499 / 15430 2 / 4363 531 / 4358 1 / 354 19.55 7.22 True + xcalL_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 13555 / 72561 3554 / 38708 3246 / 26840 380 / 5669 10.33 6.20 True + xcalL_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1821 / 57131 97 / 8702 241 / 22482 0 / 983 1.75 0.87 True + xcalL_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1631 / 15430 47 / 4363 55 / 4358 0 / 354 7.16 0.91 True + xcalL_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 3452 / 72561 567 / 38708 296 / 26840 5 / 5669 2.91 0.85 True + xcalL_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 8068 / 57131 1363 / 8702 5308 / 22482 85 / 983 1.43 16.77 True + xcalL_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 5535 / 15430 1332 / 4363 1659 / 4358 133 / 354 -5.34 -0.26 True + xcalL_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 13603 / 72561 4685 / 38708 6967 / 26840 570 / 5669 2.44 12.42 True + xcalL_K1000 ISG-high T adult sepsis vs adult HC 46 7 2258 / 162485 387 / 33194 1079 / 29747 28 / 7891 1.31 2.99 True + xcalL_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1981 / 40153 2962 / 20916 653 / 9745 623 / 3710 -15.28 -11.54 True + xcalL_K1000 ISG-high T all sepsis vs all controls 61 21 4239 / 202638 4073 / 95479 1732 / 39492 746 / 18182 -1.88 0.10 False + xcalL_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1776 / 47206 282 / 4301 130 / 6634 4 / 406 -0.81 -1.14 True + xcalL_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 1413 / 33660 289 / 4954 45 / 6525 2 / 1576 -1.20 1.05 False + xcalL_K1000 DN2 / ABC B all sepsis vs all controls 61 21 3189 / 80866 1059 / 18863 175 / 13159 37 / 4337 -0.14 0.21 False + xcalL_K1000 HSPC adult sepsis vs adult HC 46 7 376 / 310451 65 / 59344 182 / 69000 3 / 10500 0.01 0.24 True + xcalL_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 155 / 98395 26 / 35572 60 / 22500 1 / 6000 0.08 0.25 True + xcalL_K1000 HSPC all sepsis vs all controls 61 21 531 / 408846 181 / 180632 242 / 91500 26 / 31500 0.03 0.18 True + xcalL_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1221 / 83070 408 / 13845 270 / 7301 65 / 961 -1.43 -1.87 True + xcalL_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 65 / 17697 40 / 8125 48 / 3867 22 / 1293 -0.21 0.36 False + xcalL_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1286 / 100767 745 / 39446 318 / 11168 137 / 4349 -1.19 -0.29 True + xcalL_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 7033 / 310451 868 / 59344 118 / 69000 0 / 10500 1.18 0.17 True + xcalL_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1916 / 98395 231 / 35572 29 / 22500 1 / 6000 1.43 0.11 True + xcalL_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 8949 / 408846 2849 / 180632 147 / 91500 18 / 31500 0.73 0.10 True + xcalL_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 10815 / 57131 1087 / 8702 806 / 22482 14 / 983 4.18 2.27 True + xcalL_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 2878 / 15430 389 / 4363 85 / 4358 8 / 354 4.50 -0.41 False + xcalL_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 13693 / 72561 5972 / 38708 891 / 26840 168 / 5669 2.14 0.97 True + locoL_lora16sat_s26750_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3256 / 57131 103 / 8702 27 / 13971 9 / 1673 5.82 -0.33 False + locoL_lora16sat_s26750_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2105 / 15430 26 / 4363 4 / 2834 0 / 450 8.37 0.06 True + locoL_lora16sat_s26750_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5361 / 72561 503 / 38708 31 / 16805 14 / 5720 6.35 -0.07 False + locoL_lora16sat_s26750_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 934 / 187719 117 / 44192 38 / 38660 4 / 7290 0.39 0.05 True + locoL_lora16sat_s26750_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 621 / 43733 291 / 24170 15 / 10111 0 / 2921 0.14 0.20 True + locoL_lora16sat_s26750_K1000 Cycling T/NK all sepsis vs all controls 61 21 1555 / 231452 1042 / 114497 53 / 48771 13 / 17594 -0.17 0.05 False + locoL_lora16sat_s26750_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1635 / 162485 267 / 33194 41 / 30034 4 / 5278 0.45 0.09 True + locoL_lora16sat_s26750_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 756 / 40153 503 / 20916 15 / 8027 1 / 2426 -0.72 0.21 False + locoL_lora16sat_s26750_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2391 / 202638 1728 / 95479 56 / 38061 10 / 13521 -0.58 0.09 False + locoL_lora16sat_s26750_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 426 / 30034 47 / 5278 -0.06 0.74 False + locoL_lora16sat_s26750_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 143 / 8027 8 / 2426 -0.18 1.27 False + locoL_lora16sat_s26750_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 569 / 38061 102 / 13521 -0.62 0.76 False + locoL_lora16sat_s26750_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 1295 / 69000 17 / 10500 0.97 1.71 True + locoL_lora16sat_s26750_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 980 / 22500 38 / 6000 -0.14 3.72 False + locoL_lora16sat_s26750_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 2275 / 91500 144 / 31500 0.29 2.03 True + locoL_lora16sat_s26750_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 7284 / 310451 498 / 59344 1491 / 69000 42 / 10500 1.36 1.76 True + locoL_lora16sat_s26750_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4959 / 98395 2224 / 35572 1073 / 22500 68 / 6000 -1.54 3.64 False + locoL_lora16sat_s26750_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 12243 / 408846 4899 / 180632 2564 / 91500 252 / 31500 -0.09 2.00 False + locoL_lora16sat_s26750_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 7837 / 57131 16 / 8702 240 / 13971 0 / 1673 12.58 1.28 True + locoL_lora16sat_s26750_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1822 / 15430 2 / 4363 51 / 2834 0 / 450 14.20 0.94 True + locoL_lora16sat_s26750_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9659 / 72561 2342 / 38708 291 / 16805 9 / 5720 7.90 1.04 True + locoL_lora16sat_s26750_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1096 / 57131 54 / 8702 31 / 13971 1 / 1673 1.15 0.16 True + locoL_lora16sat_s26750_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1145 / 15430 26 / 4363 6 / 2834 0 / 450 4.87 0.26 True + locoL_lora16sat_s26750_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2241 / 72561 323 / 38708 37 / 16805 1 / 5720 1.95 0.21 True + locoL_lora16sat_s26750_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4692 / 57131 586 / 8702 1698 / 13971 60 / 1673 3.90 12.96 True + locoL_lora16sat_s26750_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3493 / 15430 903 / 4363 819 / 2834 67 / 450 -7.08 -0.29 True + locoL_lora16sat_s26750_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 8185 / 72561 2407 / 38708 2517 / 16805 285 / 5720 2.36 8.62 True + locoL_lora16sat_s26750_K1000 ISG-high T adult sepsis vs adult HC 46 7 1542 / 162485 241 / 33194 915 / 30034 21 / 5278 1.12 2.28 True + locoL_lora16sat_s26750_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1479 / 40153 2620 / 20916 659 / 8027 214 / 2426 -14.25 -7.79 True + locoL_lora16sat_s26750_K1000 ISG-high T all sepsis vs all controls 61 21 3021 / 202638 3344 / 95479 1574 / 38061 310 / 13521 -1.81 0.20 False + locoL_lora16sat_s26750_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1275 / 47206 194 / 4301 82 / 12972 7 / 1125 -0.39 0.03 False + locoL_lora16sat_s26750_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 952 / 33660 190 / 4954 23 / 8935 2 / 2486 -0.53 0.20 False + locoL_lora16sat_s26750_K1000 DN2 / ABC B all sepsis vs all controls 61 21 2227 / 80866 714 / 18863 105 / 21907 18 / 6947 0.11 0.21 True + locoL_lora16sat_s26750_K1000 HSPC adult sepsis vs adult HC 46 7 346 / 310451 60 / 59344 128 / 69000 6 / 10500 0.00 0.13 True + locoL_lora16sat_s26750_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 144 / 98395 24 / 35572 63 / 22500 2 / 6000 0.07 0.25 True + locoL_lora16sat_s26750_K1000 HSPC all sepsis vs all controls 61 21 490 / 408846 168 / 180632 191 / 91500 34 / 31500 0.02 0.10 True + locoL_lora16sat_s26750_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1123 / 83070 357 / 13845 213 / 10711 43 / 1202 -1.16 0.98 False + locoL_lora16sat_s26750_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 58 / 17697 30 / 8125 31 / 3019 5 / 1038 -0.10 0.95 False + locoL_lora16sat_s26750_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1181 / 100767 651 / 39446 244 / 13730 108 / 4710 -1.02 0.45 False + locoL_lora16sat_s26750_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4849 / 310451 562 / 59344 15 / 69000 1 / 10500 0.92 0.01 True + locoL_lora16sat_s26750_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1286 / 98395 145 / 35572 5 / 22500 0 / 6000 0.98 0.02 True + locoL_lora16sat_s26750_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 6135 / 408846 1813 / 180632 20 / 91500 8 / 31500 0.59 -0.00 False + locoL_lora16sat_s26750_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6433 / 57131 587 / 8702 290 / 13971 19 / 1673 3.28 0.77 True + locoL_lora16sat_s26750_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1606 / 15430 215 / 4363 58 / 2834 7 / 450 3.04 -0.24 False + locoL_lora16sat_s26750_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 8039 / 72561 3017 / 38708 348 / 16805 88 / 5720 2.46 0.45 True + locoL_lora64sat_s59000_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3219 / 57131 104 / 8702 45 / 12093 5 / 1436 5.71 0.07 True + locoL_lora64sat_s59000_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2085 / 15430 28 / 4363 4 / 3001 0 / 466 7.96 0.04 True + locoL_lora64sat_s59000_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5304 / 72561 501 / 38708 49 / 15094 13 / 5001 6.18 0.10 True + locoL_lora64sat_s59000_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 900 / 187719 108 / 44192 50 / 38020 4 / 6707 0.40 0.09 True + locoL_lora64sat_s59000_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 609 / 43733 281 / 24170 23 / 8624 0 / 2226 0.13 0.30 True + locoL_lora64sat_s59000_K1000 Cycling T/NK all sepsis vs all controls 61 21 1509 / 231452 976 / 114497 73 / 46644 14 / 16210 -0.12 0.09 False + locoL_lora64sat_s59000_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1466 / 162485 247 / 33194 37 / 28886 7 / 4495 0.34 -0.04 False + locoL_lora64sat_s59000_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 745 / 40153 438 / 20916 27 / 6585 0 / 1574 -0.44 0.44 False + locoL_lora64sat_s59000_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2211 / 202638 1518 / 95479 64 / 35471 17 / 11605 -0.45 0.05 False + locoL_lora64sat_s59000_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 467 / 28886 52 / 4495 -0.06 0.60 False + locoL_lora64sat_s59000_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 187 / 6585 20 / 1574 -0.18 1.24 False + locoL_lora64sat_s59000_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 654 / 35471 134 / 11605 -0.62 0.58 False + locoL_lora64sat_s59000_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 837 / 69000 12 / 10500 0.97 1.10 True + locoL_lora64sat_s59000_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 832 / 22500 19 / 6000 -0.14 3.38 False + locoL_lora64sat_s59000_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1669 / 91500 111 / 31500 0.29 1.47 True + locoL_lora64sat_s59000_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6677 / 310451 422 / 59344 1099 / 69000 33 / 10500 1.32 1.28 True + locoL_lora64sat_s59000_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4561 / 98395 2054 / 35572 913 / 22500 43 / 6000 -1.43 3.34 False + locoL_lora64sat_s59000_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 11238 / 408846 4441 / 180632 2012 / 91500 205 / 31500 -0.04 1.55 False + locoL_lora64sat_s59000_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 7519 / 57131 12 / 8702 169 / 12093 0 / 1436 12.11 0.91 True + locoL_lora64sat_s59000_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1746 / 15430 1 / 4363 51 / 3001 0 / 466 13.18 0.89 True + locoL_lora64sat_s59000_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9265 / 72561 2218 / 38708 220 / 15094 44 / 5001 7.51 0.42 True + locoL_lora64sat_s59000_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1028 / 57131 42 / 8702 16 / 12093 0 / 1436 1.16 0.14 True + locoL_lora64sat_s59000_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1102 / 15430 20 / 4363 10 / 3001 0 / 466 4.90 0.28 True + locoL_lora64sat_s59000_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2130 / 72561 284 / 38708 26 / 15094 2 / 5001 1.90 0.14 True + locoL_lora64sat_s59000_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4411 / 57131 559 / 8702 1486 / 12093 50 / 1436 4.86 11.11 True + locoL_lora64sat_s59000_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3372 / 15430 852 / 4363 818 / 3001 75 / 466 -6.69 4.41 False + locoL_lora64sat_s59000_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 7783 / 72561 2269 / 38708 2304 / 15094 295 / 5001 3.12 8.03 True + locoL_lora64sat_s59000_K1000 ISG-high T adult sepsis vs adult HC 46 7 1278 / 162485 180 / 33194 805 / 28886 9 / 4495 1.06 2.22 True + locoL_lora64sat_s59000_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1216 / 40153 2479 / 20916 617 / 6585 176 / 1574 -13.83 -8.29 True + locoL_lora64sat_s59000_K1000 ISG-high T all sepsis vs all controls 61 21 2494 / 202638 3055 / 95479 1422 / 35471 267 / 11605 -1.83 -0.08 True + locoL_lora64sat_s59000_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1083 / 47206 170 / 4301 91 / 15103 22 / 1585 -0.26 -0.78 True + locoL_lora64sat_s59000_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 788 / 33660 153 / 4954 31 / 10076 8 / 3116 -0.31 0.03 False + locoL_lora64sat_s59000_K1000 DN2 / ABC B all sepsis vs all controls 61 21 1871 / 80866 600 / 18863 122 / 25179 43 / 8559 0.21 -0.07 False + locoL_lora64sat_s59000_K1000 HSPC adult sepsis vs adult HC 46 7 321 / 310451 56 / 59344 265 / 69000 6 / 10500 0.00 0.33 True + locoL_lora64sat_s59000_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 143 / 98395 23 / 35572 57 / 22500 5 / 6000 0.08 0.17 True + locoL_lora64sat_s59000_K1000 HSPC all sepsis vs all controls 61 21 464 / 408846 157 / 180632 322 / 91500 51 / 31500 0.02 0.19 True + locoL_lora64sat_s59000_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1066 / 83070 346 / 13845 265 / 11211 25 / 752 -1.13 0.60 False + locoL_lora64sat_s59000_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 58 / 17697 30 / 8125 31 / 2419 9 / 741 -0.09 -0.56 True + locoL_lora64sat_s59000_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1124 / 100767 627 / 39446 296 / 13630 80 / 4216 -1.00 0.93 False + locoL_lora64sat_s59000_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4306 / 310451 487 / 59344 12 / 69000 2 / 10500 0.84 -0.00 False + locoL_lora64sat_s59000_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1070 / 98395 107 / 35572 3 / 22500 1 / 6000 0.85 -0.00 False + locoL_lora64sat_s59000_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5376 / 408846 1489 / 180632 15 / 91500 8 / 31500 0.60 -0.01 False + locoL_lora64sat_s59000_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6058 / 57131 557 / 8702 226 / 12093 23 / 1436 2.86 0.25 True + locoL_lora64sat_s59000_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1543 / 15430 167 / 4363 38 / 3001 5 / 466 2.27 -0.13 False + locoL_lora64sat_s59000_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 7601 / 72561 2838 / 38708 264 / 15094 59 / 5001 2.05 0.39 True + locoL_fullsat_s108500_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3205 / 57131 92 / 8702 43 / 11906 15 / 2017 5.69 -0.39 False + locoL_fullsat_s108500_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2063 / 15430 28 / 4363 15 / 2403 0 / 313 7.77 0.21 True + locoL_fullsat_s108500_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5268 / 72561 465 / 38708 58 / 14309 26 / 5189 6.12 -0.09 False + locoL_fullsat_s108500_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 902 / 187719 110 / 44192 106 / 39353 14 / 6301 0.38 0.05 True + locoL_fullsat_s108500_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 612 / 43733 309 / 24170 25 / 8045 4 / 2677 0.01 0.24 True + locoL_fullsat_s108500_K1000 Cycling T/NK all sepsis vs all controls 61 21 1514 / 231452 1026 / 114497 131 / 47398 39 / 16897 -0.17 0.07 False + locoL_fullsat_s108500_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1538 / 162485 254 / 33194 96 / 29483 19 / 4433 0.40 -0.06 False + locoL_fullsat_s108500_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 780 / 40153 467 / 20916 26 / 5728 5 / 2026 -0.49 0.45 False + locoL_fullsat_s108500_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2318 / 202638 1629 / 95479 122 / 35211 41 / 12371 -0.54 0.07 False + locoL_fullsat_s108500_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 550 / 29483 51 / 4433 -0.06 0.96 False + locoL_fullsat_s108500_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 165 / 5728 15 / 2026 -0.18 2.61 False + locoL_fullsat_s108500_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 715 / 35211 133 / 12371 -0.62 1.14 False + locoL_fullsat_s108500_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 2103 / 69000 18 / 10500 0.97 2.88 True + locoL_fullsat_s108500_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 1627 / 22500 44 / 6000 -0.14 6.50 False + locoL_fullsat_s108500_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 3730 / 91500 146 / 31500 0.29 3.61 True + locoL_fullsat_s108500_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6876 / 310451 465 / 59344 2645 / 69000 74 / 10500 1.31 3.13 True + locoL_fullsat_s108500_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4645 / 98395 2130 / 35572 1927 / 22500 150 / 6000 -1.58 6.06 False + locoL_fullsat_s108500_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 11521 / 408846 4627 / 180632 4572 / 91500 425 / 31500 -0.09 3.65 False + locoL_fullsat_s108500_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 7365 / 57131 14 / 8702 418 / 11906 2 / 2017 11.76 2.74 True + locoL_fullsat_s108500_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1757 / 15430 2 / 4363 99 / 2403 0 / 313 12.56 1.96 True + locoL_fullsat_s108500_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9122 / 72561 2227 / 38708 517 / 14309 24 / 5189 7.13 2.28 True + locoL_fullsat_s108500_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1015 / 57131 35 / 8702 35 / 11906 0 / 2017 1.10 0.33 True + locoL_fullsat_s108500_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1106 / 15430 22 / 4363 13 / 2403 0 / 313 4.85 0.28 True + locoL_fullsat_s108500_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2121 / 72561 273 / 38708 48 / 14309 3 / 5189 1.84 0.25 True + locoL_fullsat_s108500_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4314 / 57131 537 / 8702 2026 / 11906 189 / 2017 4.99 15.07 True + locoL_fullsat_s108500_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3386 / 15430 824 / 4363 541 / 2403 45 / 313 -6.02 -9.94 True + locoL_fullsat_s108500_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 7700 / 72561 2216 / 38708 2567 / 14309 472 / 5189 3.23 7.00 True + locoL_fullsat_s108500_K1000 ISG-high T adult sepsis vs adult HC 46 7 1470 / 162485 239 / 33194 803 / 29483 14 / 4433 1.04 2.07 True + locoL_fullsat_s108500_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1447 / 40153 2558 / 20916 751 / 5728 238 / 2026 -13.88 -7.28 True + locoL_fullsat_s108500_K1000 ISG-high T all sepsis vs all controls 61 21 2917 / 202638 3263 / 95479 1554 / 35211 399 / 12371 -1.80 -0.16 True + locoL_fullsat_s108500_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1112 / 47206 166 / 4301 145 / 14865 23 / 1195 -0.08 -1.01 True + locoL_fullsat_s108500_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 810 / 33660 175 / 4954 53 / 11345 7 / 2859 -0.50 0.27 False + locoL_fullsat_s108500_K1000 DN2 / ABC B all sepsis vs all controls 61 21 1922 / 80866 623 / 18863 198 / 26210 49 / 7650 0.20 0.08 True + locoL_fullsat_s108500_K1000 HSPC adult sepsis vs adult HC 46 7 332 / 310451 54 / 59344 269 / 69000 11 / 10500 0.01 0.29 True + locoL_fullsat_s108500_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 144 / 98395 21 / 35572 69 / 22500 6 / 6000 0.08 0.21 True + locoL_fullsat_s108500_K1000 HSPC all sepsis vs all controls 61 21 476 / 408846 154 / 180632 338 / 91500 58 / 31500 0.03 0.19 True + locoL_fullsat_s108500_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1118 / 83070 362 / 13845 231 / 9614 42 / 999 -1.18 1.04 False + locoL_fullsat_s108500_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 63 / 17697 28 / 8125 18 / 2136 10 / 763 -0.07 0.62 False + locoL_fullsat_s108500_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1181 / 100767 650 / 39446 249 / 11750 95 / 3985 -1.00 1.85 False + locoL_fullsat_s108500_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4462 / 310451 515 / 59344 12 / 69000 3 / 10500 0.88 -0.01 False + locoL_fullsat_s108500_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1143 / 98395 129 / 35572 1 / 22500 0 / 6000 0.87 0.00 True + locoL_fullsat_s108500_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5605 / 408846 1611 / 180632 13 / 91500 4 / 31500 0.57 0.00 True + locoL_fullsat_s108500_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6001 / 57131 574 / 8702 462 / 11906 45 / 2017 2.84 1.73 True + locoL_fullsat_s108500_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1531 / 15430 173 / 4363 76 / 2403 6 / 313 2.46 0.02 True + locoL_fullsat_s108500_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 7532 / 72561 2833 / 38708 538 / 14309 148 / 5189 2.11 1.07 True + locoL_scratchsat_s50000_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3356 / 57131 116 / 8702 81 / 13648 10 / 1445 5.44 -0.08 False + locoL_scratchsat_s50000_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2157 / 15430 32 / 4363 18 / 3539 0 / 424 8.59 1.62 True + locoL_scratchsat_s50000_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5513 / 72561 543 / 38708 99 / 17187 20 / 5211 6.18 0.57 True + locoL_scratchsat_s50000_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 937 / 187719 116 / 44192 29 / 42764 1 / 8096 0.40 0.06 True + locoL_scratchsat_s50000_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 633 / 43733 292 / 24170 20 / 11919 0 / 3438 0.16 0.15 True + locoL_scratchsat_s50000_K1000 Cycling T/NK all sepsis vs all controls 61 21 1570 / 231452 1023 / 114497 49 / 54683 4 / 19565 -0.13 0.07 False + locoL_scratchsat_s50000_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1568 / 162485 251 / 33194 65 / 32374 5 / 5464 0.43 0.13 True + locoL_scratchsat_s50000_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 803 / 40153 501 / 20916 24 / 8782 2 / 2358 -0.63 0.16 False + locoL_scratchsat_s50000_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2371 / 202638 1670 / 95479 89 / 41156 15 / 13867 -0.53 0.11 False + locoL_scratchsat_s50000_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 215 / 32374 21 / 5464 -0.06 0.28 False + locoL_scratchsat_s50000_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 90 / 8782 17 / 2358 -0.18 0.28 False + locoL_scratchsat_s50000_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 305 / 41156 82 / 13867 -0.62 0.04 False + locoL_scratchsat_s50000_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 404 / 69000 16 / 10500 0.97 0.43 True + locoL_scratchsat_s50000_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 370 / 22500 10 / 6000 -0.14 1.48 False + locoL_scratchsat_s50000_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 774 / 91500 81 / 31500 0.29 0.59 True + locoL_scratchsat_s50000_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 7249 / 310451 506 / 59344 688 / 69000 48 / 10500 1.35 0.54 True + locoL_scratchsat_s50000_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4905 / 98395 2206 / 35572 543 / 22500 56 / 6000 -1.55 1.48 False + locoL_scratchsat_s50000_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 12154 / 408846 4902 / 180632 1231 / 91500 252 / 31500 -0.11 0.55 False + locoL_scratchsat_s50000_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 8563 / 57131 18 / 8702 417 / 13648 1 / 1445 13.79 2.30 True + locoL_scratchsat_s50000_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 2016 / 15430 3 / 4363 60 / 3539 0 / 424 15.33 1.11 True + locoL_scratchsat_s50000_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 10579 / 72561 2648 / 38708 477 / 17187 117 / 5211 8.45 1.12 True + locoL_scratchsat_s50000_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1247 / 57131 58 / 8702 26 / 13648 3 / 1445 1.10 -0.13 False + locoL_scratchsat_s50000_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1247 / 15430 30 / 4363 5 / 3539 2 / 424 5.85 -0.33 False + locoL_scratchsat_s50000_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2494 / 72561 352 / 38708 31 / 17187 7 / 5211 2.18 -0.05 False + locoL_scratchsat_s50000_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 5326 / 57131 719 / 8702 1491 / 13648 46 / 1445 3.67 10.65 True + locoL_scratchsat_s50000_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3932 / 15430 1003 / 4363 560 / 3539 91 / 424 -8.35 -4.77 True + locoL_scratchsat_s50000_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 9258 / 72561 2823 / 38708 2051 / 17187 235 / 5211 2.09 5.48 True + locoL_scratchsat_s50000_K1000 ISG-high T adult sepsis vs adult HC 46 7 1560 / 162485 244 / 33194 526 / 32374 2 / 5464 1.15 1.30 True + locoL_scratchsat_s50000_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1471 / 40153 2609 / 20916 657 / 8782 150 / 2358 -14.18 -2.61 True + locoL_scratchsat_s50000_K1000 ISG-high T all sepsis vs all controls 61 21 3031 / 202638 3333 / 95479 1183 / 41156 170 / 13867 -1.79 0.66 False + locoL_scratchsat_s50000_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1225 / 47206 193 / 4301 94 / 10611 5 / 723 -0.52 -0.08 True + locoL_scratchsat_s50000_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 916 / 33660 182 / 4954 34 / 6415 8 / 2000 -0.43 0.20 False + locoL_scratchsat_s50000_K1000 DN2 / ABC B all sepsis vs all controls 61 21 2141 / 80866 704 / 18863 128 / 17026 37 / 5902 0.00 0.11 True + locoL_scratchsat_s50000_K1000 HSPC adult sepsis vs adult HC 46 7 346 / 310451 59 / 59344 80 / 69000 2 / 10500 0.01 0.10 True + locoL_scratchsat_s50000_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 139 / 98395 23 / 35572 41 / 22500 2 / 6000 0.07 0.15 True + locoL_scratchsat_s50000_K1000 HSPC all sepsis vs all controls 61 21 485 / 408846 162 / 180632 121 / 91500 31 / 31500 0.03 0.03 True + locoL_scratchsat_s50000_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1131 / 83070 359 / 13845 192 / 12481 27 / 1761 -1.18 2.28 False + locoL_scratchsat_s50000_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 55 / 17697 32 / 8125 23 / 3414 10 / 992 -0.14 -0.10 True + locoL_scratchsat_s50000_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1186 / 100767 647 / 39446 215 / 15895 66 / 5206 -0.94 1.53 False + locoL_scratchsat_s50000_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4796 / 310451 519 / 59344 68 / 69000 4 / 10500 0.96 0.06 True + locoL_scratchsat_s50000_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1215 / 98395 134 / 35572 14 / 22500 1 / 6000 0.94 0.05 True + locoL_scratchsat_s50000_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 6011 / 408846 1740 / 180632 82 / 91500 14 / 31500 0.60 0.05 True + locoL_scratchsat_s50000_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 7238 / 57131 693 / 8702 456 / 13648 11 / 1445 3.39 1.93 True + locoL_scratchsat_s50000_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1847 / 15430 214 / 4363 89 / 3539 9 / 424 2.52 -0.05 False + locoL_scratchsat_s50000_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 9085 / 72561 3555 / 38708 545 / 17187 86 / 5211 2.20 1.11 True +locoL_scratchsat_s100000_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3297 / 57131 111 / 8702 91 / 13940 7 / 1381 5.80 0.01 True +locoL_scratchsat_s100000_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2104 / 15430 26 / 4363 17 / 3633 0 / 507 8.44 0.28 True +locoL_scratchsat_s100000_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5401 / 72561 508 / 38708 108 / 17573 17 / 5314 6.40 0.17 True +locoL_scratchsat_s100000_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 882 / 187719 116 / 44192 52 / 40961 0 / 7687 0.34 0.13 True +locoL_scratchsat_s100000_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 585 / 43733 288 / 24170 25 / 11212 2 / 3133 0.06 0.16 True +locoL_scratchsat_s100000_K1000 Cycling T/NK all sepsis vs all controls 61 21 1467 / 231452 996 / 114497 77 / 52173 6 / 18508 -0.18 0.12 False +locoL_scratchsat_s100000_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1506 / 162485 232 / 33194 76 / 31359 4 / 5365 0.47 0.19 True +locoL_scratchsat_s100000_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 738 / 40153 479 / 20916 33 / 8511 4 / 2035 -0.65 0.22 False +locoL_scratchsat_s100000_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2244 / 202638 1593 / 95479 109 / 39870 12 / 13145 -0.48 0.20 False +locoL_scratchsat_s100000_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 263 / 31359 37 / 5365 -0.06 0.24 False +locoL_scratchsat_s100000_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 118 / 8511 13 / 2035 -0.18 0.76 False +locoL_scratchsat_s100000_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 381 / 39870 83 / 13145 -0.62 0.35 False +locoL_scratchsat_s100000_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 552 / 69000 29 / 10500 0.97 0.52 True +locoL_scratchsat_s100000_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 508 / 22500 22 / 6000 -0.14 1.89 False +locoL_scratchsat_s100000_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1060 / 91500 126 / 31500 0.29 0.76 True +locoL_scratchsat_s100000_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6835 / 310451 442 / 59344 782 / 69000 59 / 10500 1.35 0.57 True +locoL_scratchsat_s100000_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4672 / 98395 2092 / 35572 657 / 22500 67 / 6000 -1.43 1.80 False +locoL_scratchsat_s100000_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 11507 / 408846 4533 / 180632 1439 / 91500 274 / 31500 -0.03 0.70 False +locoL_scratchsat_s100000_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 8044 / 57131 16 / 8702 284 / 13940 0 / 1381 12.75 1.48 True +locoL_scratchsat_s100000_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1912 / 15430 2 / 4363 35 / 3633 0 / 507 15.41 0.74 True +locoL_scratchsat_s100000_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9956 / 72561 2447 / 38708 319 / 17573 99 / 5314 8.08 0.58 True +locoL_scratchsat_s100000_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1116 / 57131 57 / 8702 16 / 13940 0 / 1381 0.93 0.10 True +locoL_scratchsat_s100000_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1146 / 15430 22 / 4363 8 / 3633 0 / 507 4.91 0.13 True +locoL_scratchsat_s100000_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2262 / 72561 301 / 38708 24 / 17573 2 / 5314 1.84 0.10 True +locoL_scratchsat_s100000_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4873 / 57131 636 / 8702 1233 / 13940 42 / 1381 4.12 9.46 True +locoL_scratchsat_s100000_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3703 / 15430 940 / 4363 455 / 3633 103 / 507 -6.18 -5.35 True +locoL_scratchsat_s100000_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 8576 / 72561 2537 / 38708 1688 / 17573 238 / 5314 2.80 4.91 True +locoL_scratchsat_s100000_K1000 ISG-high T adult sepsis vs adult HC 46 7 1366 / 162485 220 / 33194 385 / 31359 3 / 5365 0.96 0.97 True +locoL_scratchsat_s100000_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1353 / 40153 2547 / 20916 529 / 8511 120 / 2035 -14.00 -2.65 True +locoL_scratchsat_s100000_K1000 ISG-high T all sepsis vs all controls 61 21 2719 / 202638 3187 / 95479 914 / 39870 142 / 13145 -1.88 0.37 False +locoL_scratchsat_s100000_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1149 / 47206 168 / 4301 97 / 11421 13 / 1089 -0.26 -0.35 True +locoL_scratchsat_s100000_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 851 / 33660 186 / 4954 29 / 6683 13 / 2143 -0.82 -0.15 True +locoL_scratchsat_s100000_K1000 DN2 / ABC B all sepsis vs all controls 61 21 2000 / 80866 653 / 18863 126 / 18104 47 / 6471 0.18 -0.02 False +locoL_scratchsat_s100000_K1000 HSPC adult sepsis vs adult HC 46 7 349 / 310451 60 / 59344 208 / 69000 13 / 10500 0.01 0.18 True +locoL_scratchsat_s100000_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 146 / 98395 23 / 35572 108 / 22500 24 / 6000 0.08 0.08 True +locoL_scratchsat_s100000_K1000 HSPC all sepsis vs all controls 61 21 495 / 408846 164 / 180632 316 / 91500 91 / 31500 0.03 0.06 True +locoL_scratchsat_s100000_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1095 / 83070 353 / 13845 194 / 11947 31 / 1764 -1.18 1.22 False +locoL_scratchsat_s100000_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 61 / 17697 28 / 8125 36 / 3408 6 / 898 -0.05 1.41 False +locoL_scratchsat_s100000_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1156 / 100767 633 / 39446 230 / 15355 64 / 4970 -0.94 1.31 False +locoL_scratchsat_s100000_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4555 / 310451 491 / 59344 22 / 69000 2 / 10500 0.92 0.01 True +locoL_scratchsat_s100000_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1129 / 98395 122 / 35572 6 / 22500 0 / 6000 0.88 0.03 True +locoL_scratchsat_s100000_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5684 / 408846 1601 / 180632 28 / 91500 8 / 31500 0.60 0.01 True +locoL_scratchsat_s100000_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6721 / 57131 626 / 8702 405 / 13940 16 / 1381 3.28 1.66 True +locoL_scratchsat_s100000_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1698 / 15430 195 / 4363 83 / 3633 4 / 507 2.70 1.27 True +locoL_scratchsat_s100000_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 8419 / 72561 3197 / 38708 488 / 17573 85 / 5314 2.22 1.43 True +locoL_scratchsat_s150000_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3305 / 57131 107 / 8702 60 / 15214 2 / 1300 5.81 0.31 True +locoL_scratchsat_s150000_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2113 / 15430 25 / 4363 17 / 4025 1 / 588 8.08 0.14 True +locoL_scratchsat_s150000_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5418 / 72561 507 / 38708 77 / 19239 15 / 5473 6.30 0.22 True +locoL_scratchsat_s150000_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 902 / 187719 113 / 44192 28 / 39684 1 / 7820 0.38 0.06 True +locoL_scratchsat_s150000_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 604 / 43733 287 / 24170 18 / 10585 0 / 2711 0.10 0.16 True +locoL_scratchsat_s150000_K1000 Cycling T/NK all sepsis vs all controls 61 21 1506 / 231452 1013 / 114497 46 / 50269 3 / 17756 -0.17 0.07 False +locoL_scratchsat_s150000_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1494 / 162485 230 / 33194 47 / 30823 1 / 5634 0.46 0.13 True +locoL_scratchsat_s150000_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 727 / 40153 466 / 20916 23 / 8060 0 / 1712 -0.59 0.31 False +locoL_scratchsat_s150000_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2221 / 202638 1553 / 95479 70 / 38883 5 / 12841 -0.47 0.15 False +locoL_scratchsat_s150000_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 254 / 30823 39 / 5634 -0.06 0.20 False +locoL_scratchsat_s150000_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 114 / 8060 17 / 1712 -0.18 0.36 False +locoL_scratchsat_s150000_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 368 / 38883 102 / 12841 -0.62 0.07 False +locoL_scratchsat_s150000_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 656 / 69000 29 / 10500 0.97 0.67 True +locoL_scratchsat_s150000_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 548 / 22500 44 / 6000 -0.14 1.70 False +locoL_scratchsat_s150000_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1204 / 91500 189 / 31500 0.29 0.72 True +locoL_scratchsat_s150000_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6864 / 310451 457 / 59344 855 / 69000 47 / 10500 1.31 0.79 True +locoL_scratchsat_s150000_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4675 / 98395 2123 / 35572 676 / 22500 86 / 6000 -1.52 1.57 False +locoL_scratchsat_s150000_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 11539 / 408846 4643 / 180632 1531 / 91500 303 / 31500 -0.09 0.71 False +locoL_scratchsat_s150000_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 8078 / 57131 16 / 8702 282 / 15214 0 / 1300 12.93 1.29 True +locoL_scratchsat_s150000_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1886 / 15430 2 / 4363 40 / 4025 0 / 588 14.46 0.80 True +locoL_scratchsat_s150000_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9964 / 72561 2415 / 38708 322 / 19239 101 / 5473 8.05 0.47 True +locoL_scratchsat_s150000_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1135 / 57131 54 / 8702 18 / 15214 0 / 1300 1.09 0.15 True +locoL_scratchsat_s150000_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1167 / 15430 25 / 4363 2 / 4025 0 / 588 5.23 0.03 True +locoL_scratchsat_s150000_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2302 / 72561 341 / 38708 20 / 19239 3 / 5473 1.94 0.10 True +locoL_scratchsat_s150000_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4902 / 57131 647 / 8702 1546 / 15214 32 / 1300 3.96 11.00 True +locoL_scratchsat_s150000_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3641 / 15430 938 / 4363 567 / 4025 122 / 588 -7.63 -4.23 True +locoL_scratchsat_s150000_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 8543 / 72561 2549 / 38708 2113 / 19239 269 / 5473 2.52 6.42 True +locoL_scratchsat_s150000_K1000 ISG-high T adult sepsis vs adult HC 46 7 1325 / 162485 210 / 33194 403 / 30823 4 / 5634 0.98 0.99 True +locoL_scratchsat_s150000_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1311 / 40153 2512 / 20916 573 / 8060 91 / 1712 -13.88 -2.49 True +locoL_scratchsat_s150000_K1000 ISG-high T all sepsis vs all controls 61 21 2636 / 202638 3134 / 95479 976 / 38883 114 / 12841 -1.86 0.42 False +locoL_scratchsat_s150000_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1066 / 47206 167 / 4301 120 / 11935 14 / 1125 -0.35 -0.25 True +locoL_scratchsat_s150000_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 810 / 33660 147 / 4954 35 / 7114 8 / 2503 0.02 0.20 True +locoL_scratchsat_s150000_K1000 DN2 / ABC B all sepsis vs all controls 61 21 1876 / 80866 607 / 18863 155 / 19049 45 / 7341 0.21 0.14 True +locoL_scratchsat_s150000_K1000 HSPC adult sepsis vs adult HC 46 7 346 / 310451 60 / 59344 107 / 69000 4 / 10500 0.01 0.12 True +locoL_scratchsat_s150000_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 141 / 98395 20 / 35572 41 / 22500 4 / 6000 0.09 0.12 True +locoL_scratchsat_s150000_K1000 HSPC all sepsis vs all controls 61 21 487 / 408846 154 / 180632 148 / 91500 36 / 31500 0.03 0.05 True +locoL_scratchsat_s150000_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1055 / 83070 342 / 13845 181 / 11385 31 / 1777 -1.20 1.55 False +locoL_scratchsat_s150000_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 56 / 17697 28 / 8125 38 / 3195 7 / 705 -0.13 1.06 False +locoL_scratchsat_s150000_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1111 / 100767 622 / 39446 219 / 14580 62 / 4577 -1.11 1.22 False +locoL_scratchsat_s150000_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4459 / 310451 487 / 59344 31 / 69000 3 / 10500 0.92 0.02 True +locoL_scratchsat_s150000_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1098 / 98395 131 / 35572 7 / 22500 1 / 6000 0.82 0.01 True +locoL_scratchsat_s150000_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5557 / 408846 1597 / 180632 38 / 91500 13 / 31500 0.59 0.00 True +locoL_scratchsat_s150000_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6616 / 57131 631 / 8702 327 / 15214 12 / 1300 2.89 1.57 True +locoL_scratchsat_s150000_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1699 / 15430 179 / 4363 43 / 4025 5 / 588 4.21 -0.10 False +locoL_scratchsat_s150000_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 8315 / 72561 3252 / 38708 370 / 19239 57 / 5473 2.26 1.06 True +locoL_scratchsat_s162000_K1000 C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3266 / 57131 106 / 8702 54 / 12850 1 / 1198 5.38 0.34 True +locoL_scratchsat_s162000_K1000 C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2089 / 15430 24 / 4363 10 / 3189 1 / 454 8.45 0.02 True +locoL_scratchsat_s162000_K1000 C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5355 / 72561 497 / 38708 64 / 16039 16 / 4778 6.08 0.21 True +locoL_scratchsat_s162000_K1000 Cycling T/NK adult sepsis vs adult HC 46 7 914 / 187719 113 / 44192 24 / 42143 1 / 7914 0.38 0.05 True +locoL_scratchsat_s162000_K1000 Cycling T/NK paediatric sepsis vs paediatric HC 15 4 586 / 43733 295 / 24170 12 / 11353 0 / 2930 0.04 0.09 True +locoL_scratchsat_s162000_K1000 Cycling T/NK all sepsis vs all controls 61 21 1500 / 231452 987 / 114497 36 / 53496 3 / 18535 -0.14 0.05 False +locoL_scratchsat_s162000_K1000 Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 1502 / 162485 247 / 33194 30 / 32961 1 / 5739 0.40 0.07 True +locoL_scratchsat_s162000_K1000 Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 706 / 40153 466 / 20916 17 / 8754 2 / 1992 -0.66 0.06 False +locoL_scratchsat_s162000_K1000 Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 2208 / 202638 1551 / 95479 47 / 41715 7 / 13640 -0.45 0.03 False +locoL_scratchsat_s162000_K1000 Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 254 / 32961 40 / 5739 -0.06 0.12 False +locoL_scratchsat_s162000_K1000 Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 122 / 8754 20 / 1992 -0.18 0.36 False +locoL_scratchsat_s162000_K1000 Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 376 / 41715 102 / 13640 -0.62 0.11 False +locoL_scratchsat_s162000_K1000 Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 700 / 69000 32 / 10500 0.97 0.71 True +locoL_scratchsat_s162000_K1000 Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 628 / 22500 52 / 6000 -0.14 1.92 False +locoL_scratchsat_s162000_K1000 Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1328 / 91500 206 / 31500 0.29 0.80 True +locoL_scratchsat_s162000_K1000 Plasmablast (markers) adult sepsis vs adult HC 46 7 6802 / 310451 477 / 59344 873 / 69000 54 / 10500 1.27 0.75 True +locoL_scratchsat_s162000_K1000 Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 4637 / 98395 2052 / 35572 742 / 22500 87 / 6000 -1.37 1.85 False +locoL_scratchsat_s162000_K1000 Plasmablast (markers) all sepsis vs all controls 61 21 11439 / 408846 4578 / 180632 1615 / 91500 308 / 31500 -0.08 0.79 False +locoL_scratchsat_s162000_K1000 MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 7810 / 57131 12 / 8702 231 / 12850 1 / 1198 12.52 1.49 True +locoL_scratchsat_s162000_K1000 MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 1869 / 15430 1 / 4363 30 / 3189 0 / 454 14.41 0.77 True +locoL_scratchsat_s162000_K1000 MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 9679 / 72561 2368 / 38708 261 / 16039 102 / 4778 7.83 0.60 True +locoL_scratchsat_s162000_K1000 Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1105 / 57131 42 / 8702 12 / 12850 0 / 1198 1.12 0.07 True +locoL_scratchsat_s162000_K1000 Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1115 / 15430 20 / 4363 3 / 3189 0 / 454 4.68 0.05 True +locoL_scratchsat_s162000_K1000 Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 2220 / 72561 294 / 38708 15 / 16039 2 / 4778 1.83 0.04 True +locoL_scratchsat_s162000_K1000 ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 4710 / 57131 606 / 8702 1234 / 12850 37 / 1198 4.56 10.19 True +locoL_scratchsat_s162000_K1000 ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 3510 / 15430 916 / 4363 428 / 3189 94 / 454 -8.24 -3.14 True +locoL_scratchsat_s162000_K1000 ISG-high monocyte (positive control) all sepsis vs all controls 61 21 8220 / 72561 2446 / 38708 1662 / 16039 219 / 4778 2.66 6.28 True +locoL_scratchsat_s162000_K1000 ISG-high T adult sepsis vs adult HC 46 7 1347 / 162485 224 / 33194 484 / 32961 4 / 5739 0.95 1.18 True +locoL_scratchsat_s162000_K1000 ISG-high T paediatric sepsis vs paediatric HC 15 4 1288 / 40153 2470 / 20916 564 / 8754 104 / 1992 -13.71 -2.10 True +locoL_scratchsat_s162000_K1000 ISG-high T all sepsis vs all controls 61 21 2635 / 202638 3116 / 95479 1048 / 41715 128 / 13640 -1.83 0.63 False +locoL_scratchsat_s162000_K1000 DN2 / ABC B adult sepsis vs adult HC 46 7 1108 / 47206 174 / 4301 98 / 11990 11 / 1134 -0.27 -0.27 True +locoL_scratchsat_s162000_K1000 DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 781 / 33660 162 / 4954 37 / 7307 8 / 2458 -0.52 0.31 False +locoL_scratchsat_s162000_K1000 DN2 / ABC B all sepsis vs all controls 61 21 1889 / 80866 618 / 18863 135 / 19297 43 / 7340 0.12 0.01 True +locoL_scratchsat_s162000_K1000 HSPC adult sepsis vs adult HC 46 7 337 / 310451 61 / 59344 140 / 69000 5 / 10500 0.00 0.16 True +locoL_scratchsat_s162000_K1000 HSPC paediatric sepsis vs paediatric HC 15 4 139 / 98395 24 / 35572 46 / 22500 6 / 6000 0.07 0.10 True +locoL_scratchsat_s162000_K1000 HSPC all sepsis vs all controls 61 21 476 / 408846 164 / 180632 186 / 91500 36 / 31500 0.03 0.09 True +locoL_scratchsat_s162000_K1000 Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1081 / 83070 336 / 13845 232 / 12316 27 / 1892 -1.03 2.34 False +locoL_scratchsat_s162000_K1000 Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 58 / 17697 27 / 8125 35 / 3281 6 / 755 -0.06 0.86 False +locoL_scratchsat_s162000_K1000 Cytotoxic CD4 T all sepsis vs all controls 61 21 1139 / 100767 616 / 39446 267 / 15597 62 / 4927 -0.98 1.60 False +locoL_scratchsat_s162000_K1000 Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 4449 / 310451 495 / 59344 21 / 69000 1 / 10500 0.87 0.02 True +locoL_scratchsat_s162000_K1000 Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 1107 / 98395 118 / 35572 4 / 22500 0 / 6000 0.86 0.02 True +locoL_scratchsat_s162000_K1000 Granulocyte-like (LDG) all sepsis vs all controls 61 21 5556 / 408846 1607 / 180632 25 / 91500 6 / 31500 0.56 0.01 True +locoL_scratchsat_s162000_K1000 Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 6446 / 57131 616 / 8702 258 / 12850 11 / 1198 2.74 1.02 True +locoL_scratchsat_s162000_K1000 Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 1573 / 15430 184 / 4363 41 / 3189 4 / 454 3.54 0.06 True +locoL_scratchsat_s162000_K1000 Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 8019 / 72561 3076 / 38708 299 / 16039 40 / 4778 2.24 0.96 True + within_lora_n5__raw C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3704 / 57131 139 / 8702 448 / 13072 51 / 1244 6.09 -0.80 False + within_lora_n5__raw C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2285 / 15430 38 / 4363 120 / 3123 2 / 364 9.20 1.09 True + within_lora_n5__raw C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5989 / 72561 631 / 38708 568 / 16195 100 / 5020 6.84 0.19 True + within_lora_n5__raw Cycling T/NK adult sepsis vs adult HC 46 7 1171 / 187719 143 / 44192 109 / 43361 15 / 8256 0.49 0.10 True + within_lora_n5__raw Cycling T/NK paediatric sepsis vs paediatric HC 15 4 764 / 43733 425 / 24170 38 / 12274 11 / 4052 -0.16 0.09 False + within_lora_n5__raw Cycling T/NK all sepsis vs all controls 61 21 1935 / 231452 1382 / 114497 147 / 55635 46 / 20628 -0.32 0.09 False + within_lora_n5__raw Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 2248 / 162485 386 / 33194 127 / 40042 14 / 7775 0.47 0.21 True + within_lora_n5__raw Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 968 / 40153 699 / 20916 44 / 11582 6 / 3892 -1.25 0.24 False + within_lora_n5__raw Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 3216 / 202638 2298 / 95479 171 / 51624 40 / 19483 -0.81 0.18 False + within_lora_n5__raw Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 377 / 40042 76 / 7775 -0.06 0.07 False + within_lora_n5__raw Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 145 / 11582 35 / 3892 -0.18 0.36 False + within_lora_n5__raw Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 522 / 51624 174 / 19483 -0.62 0.20 False + within_lora_n5__raw Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 416 / 69000 8 / 10500 0.97 0.53 True + within_lora_n5__raw Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 221 / 22500 6 / 6000 -0.14 0.88 False + within_lora_n5__raw Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 637 / 91500 68 / 31500 0.29 0.48 True + within_lora_n5__raw Plasmablast (markers) adult sepsis vs adult HC 46 7 10726 / 310451 883 / 59344 565 / 69000 20 / 10500 1.76 0.63 True + within_lora_n5__raw Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 7063 / 98395 2898 / 35572 306 / 22500 16 / 6000 -1.36 1.09 False + within_lora_n5__raw Plasmablast (markers) all sepsis vs all controls 61 21 17789 / 408846 6876 / 180632 871 / 91500 124 / 31500 0.04 0.56 True + within_lora_n5__raw MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 11246 / 57131 41 / 8702 1241 / 13072 0 / 1244 17.90 4.63 True + within_lora_n5__raw MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 2570 / 15430 7 / 4363 836 / 3123 0 / 364 19.98 11.42 True + within_lora_n5__raw MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 13816 / 72561 3645 / 38708 2077 / 16195 94 / 5020 10.65 5.30 True + within_lora_n5__raw Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1860 / 57131 89 / 8702 157 / 13072 1 / 1244 1.92 0.53 True + within_lora_n5__raw Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1641 / 15430 47 / 4363 65 / 3123 1 / 364 7.14 0.76 True + within_lora_n5__raw Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 3501 / 72561 551 / 38708 222 / 16195 8 / 5020 3.01 0.57 True + within_lora_n5__raw ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 8265 / 57131 1400 / 8702 1186 / 13072 34 / 1244 1.30 2.49 True + within_lora_n5__raw ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 5623 / 15430 1367 / 4363 537 / 3123 87 / 364 -5.62 -6.13 True + within_lora_n5__raw ISG-high monocyte (positive control) all sepsis vs all controls 61 21 13888 / 72561 4855 / 38708 1723 / 16195 221 / 5020 2.31 1.82 True + within_lora_n5__raw ISG-high T adult sepsis vs adult HC 46 7 2849 / 162485 462 / 33194 357 / 40042 13 / 7775 1.64 0.86 True + within_lora_n5__raw ISG-high T paediatric sepsis vs paediatric HC 15 4 2409 / 40153 3145 / 20916 295 / 11582 203 / 3892 -15.49 -3.69 True + within_lora_n5__raw ISG-high T all sepsis vs all controls 61 21 5258 / 202638 4514 / 95479 652 / 51624 244 / 19483 -1.68 0.02 False + within_lora_n5__raw DN2 / ABC B adult sepsis vs adult HC 46 7 1697 / 47206 265 / 4301 212 / 9721 15 / 860 -0.69 0.74 False + within_lora_n5__raw DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 1343 / 33660 264 / 4954 85 / 6522 10 / 1539 -0.90 1.35 False + within_lora_n5__raw DN2 / ABC B all sepsis vs all controls 61 21 3040 / 80866 979 / 18863 297 / 16243 58 / 5131 -0.01 0.90 False + within_lora_n5__raw HSPC adult sepsis vs adult HC 46 7 378 / 310451 65 / 59344 70 / 69000 0 / 10500 0.01 0.10 True + within_lora_n5__raw HSPC paediatric sepsis vs paediatric HC 15 4 154 / 98395 28 / 35572 20 / 22500 4 / 6000 0.07 0.02 True + within_lora_n5__raw HSPC all sepsis vs all controls 61 21 532 / 408846 183 / 180632 90 / 91500 25 / 31500 0.03 0.02 True + within_lora_n5__raw Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1230 / 83070 409 / 13845 289 / 18489 122 / 3295 -1.41 -2.36 True + within_lora_n5__raw Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 70 / 17697 40 / 8125 47 / 5442 14 / 2007 -0.20 0.11 False + within_lora_n5__raw Cytotoxic CD4 T all sepsis vs all controls 61 21 1300 / 100767 747 / 39446 336 / 23931 197 / 9331 -1.16 -0.73 True + within_lora_n5__raw Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 7612 / 310451 984 / 59344 74 / 69000 5 / 10500 1.20 0.06 True + within_lora_n5__raw Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 2104 / 98395 269 / 35572 14 / 22500 3 / 6000 1.53 0.01 True + within_lora_n5__raw Granulocyte-like (LDG) all sepsis vs all controls 61 21 9716 / 408846 3268 / 180632 88 / 91500 20 / 31500 0.67 0.03 True + within_lora_n5__raw Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 11028 / 57131 1094 / 8702 1567 / 13072 72 / 1244 4.53 4.62 True + within_lora_n5__raw Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 2991 / 15430 396 / 4363 292 / 3123 7 / 364 4.56 5.62 True + within_lora_n5__raw Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 14019 / 72561 6153 / 38708 1859 / 16195 348 / 5020 2.14 3.15 True + within_real_lora__raw C1Q-high monocyte (reference) adult sepsis vs adult HC 46 7 3691 / 57131 139 / 8702 497 / 14087 22 / 1527 6.05 1.63 True + within_real_lora__raw C1Q-high monocyte (reference) paediatric sepsis vs paediatric HC 15 4 2278 / 15430 39 / 4363 127 / 3327 0 / 522 9.04 4.32 True + within_real_lora__raw C1Q-high monocyte (reference) all sepsis vs all controls 61 21 5969 / 72561 627 / 38708 624 / 17414 63 / 5321 6.77 2.35 True + within_real_lora__raw Cycling T/NK adult sepsis vs adult HC 46 7 1216 / 187719 151 / 44192 156 / 42558 25 / 8067 0.51 0.11 True + within_real_lora__raw Cycling T/NK paediatric sepsis vs paediatric HC 15 4 783 / 43733 454 / 24170 159 / 11835 34 / 4619 -0.24 0.45 False + within_real_lora__raw Cycling T/NK all sepsis vs all controls 61 21 1999 / 231452 1460 / 114497 315 / 54393 81 / 21182 -0.37 0.22 False + within_real_lora__raw Cycling activated T (CD38/HLA-DR) adult sepsis vs adult HC 46 7 2389 / 162485 422 / 33194 154 / 37959 24 / 6894 0.45 0.10 True + within_real_lora__raw Cycling activated T (CD38/HLA-DR) paediatric sepsis vs paediatric HC 15 4 1008 / 40153 750 / 20916 174 / 11007 30 / 4237 -1.42 0.63 False + within_real_lora__raw Cycling activated T (CD38/HLA-DR) all sepsis vs all controls 61 21 3397 / 202638 2460 / 95479 328 / 48966 71 / 18885 -0.90 0.29 False + within_real_lora__raw Proliferating T (label) adult sepsis vs adult HC 46 7 1725 / 162485 439 / 33194 388 / 37959 82 / 6894 -0.06 -0.04 True + within_real_lora__raw Proliferating T (label) paediatric sepsis vs paediatric HC 15 4 1130 / 40153 542 / 20916 282 / 11007 49 / 4237 -0.18 1.05 False + within_real_lora__raw Proliferating T (label) all sepsis vs all controls 61 21 2855 / 202638 1938 / 95479 670 / 48966 191 / 18885 -0.62 0.37 False + within_real_lora__raw Plasmablast (label) adult sepsis vs adult HC 46 7 3601 / 310451 90 / 59344 701 / 69000 20 / 10500 0.97 0.83 True + within_real_lora__raw Plasmablast (label) paediatric sepsis vs paediatric HC 15 4 2779 / 98395 1000 / 35572 526 / 22500 21 / 6000 -0.14 1.99 False + within_real_lora__raw Plasmablast (label) all sepsis vs all controls 61 21 6380 / 408846 2043 / 180632 1227 / 91500 100 / 31500 0.29 1.02 True + within_real_lora__raw Plasmablast (markers) adult sepsis vs adult HC 46 7 11212 / 310451 946 / 59344 913 / 69000 37 / 10500 1.80 0.97 True + within_real_lora__raw Plasmablast (markers) paediatric sepsis vs paediatric HC 15 4 7396 / 98395 2975 / 35572 685 / 22500 47 / 6000 -1.25 2.26 False + within_real_lora__raw Plasmablast (markers) all sepsis vs all controls 61 21 18608 / 408846 7164 / 180632 1598 / 91500 185 / 31500 0.05 1.16 True + within_real_lora__raw MS1 monocyte (IL1R2+) adult sepsis vs adult HC 46 7 11189 / 57131 46 / 8702 1652 / 14087 1 / 1527 17.68 11.46 True + within_real_lora__raw MS1 monocyte (IL1R2+) paediatric sepsis vs paediatric HC 15 4 2529 / 15430 7 / 4363 553 / 3327 1 / 522 20.09 13.30 True + within_real_lora__raw MS1 monocyte (IL1R2+) all sepsis vs all controls 61 21 13718 / 72561 3628 / 38708 2205 / 17414 330 / 5321 10.59 9.29 True + within_real_lora__raw Cycling monocyte (Ye 2026) adult sepsis vs adult HC 46 7 1879 / 57131 95 / 8702 145 / 14087 4 / 1527 1.87 0.31 True + within_real_lora__raw Cycling monocyte (Ye 2026) paediatric sepsis vs paediatric HC 15 4 1644 / 15430 47 / 4363 31 / 3327 1 / 522 7.26 1.09 True + within_real_lora__raw Cycling monocyte (Ye 2026) all sepsis vs all controls 61 21 3523 / 72561 555 / 38708 176 / 17414 21 / 5321 3.01 0.40 True + within_real_lora__raw ISG-high monocyte (positive control) adult sepsis vs adult HC 46 7 8244 / 57131 1422 / 8702 1290 / 14087 44 / 1527 0.92 4.41 True + within_real_lora__raw ISG-high monocyte (positive control) paediatric sepsis vs paediatric HC 15 4 5579 / 15430 1381 / 4363 823 / 3327 73 / 522 -7.55 -11.53 True + within_real_lora__raw ISG-high monocyte (positive control) all sepsis vs all controls 61 21 13823 / 72561 4836 / 38708 2113 / 17414 186 / 5321 1.77 1.68 True + within_real_lora__raw ISG-high T adult sepsis vs adult HC 46 7 3220 / 162485 539 / 33194 292 / 37959 26 / 6894 1.69 0.43 True + within_real_lora__raw ISG-high T paediatric sepsis vs paediatric HC 15 4 2615 / 40153 3243 / 20916 434 / 11007 604 / 4237 -15.61 -7.59 True + within_real_lora__raw ISG-high T all sepsis vs all controls 61 21 5835 / 202638 4813 / 95479 726 / 48966 679 / 18885 -1.65 -0.95 True + within_real_lora__raw DN2 / ABC B adult sepsis vs adult HC 46 7 1713 / 47206 278 / 4301 141 / 9132 16 / 567 -0.93 -0.78 True + within_real_lora__raw DN2 / ABC B paediatric sepsis vs paediatric HC 15 4 1350 / 33660 269 / 4954 43 / 6762 15 / 705 -0.94 -1.74 True + within_real_lora__raw DN2 / ABC B all sepsis vs all controls 61 21 3063 / 80866 1018 / 18863 184 / 15894 49 / 4006 -0.14 -0.28 True + within_real_lora__raw HSPC adult sepsis vs adult HC 46 7 386 / 310451 68 / 59344 42 / 69000 10 / 10500 0.01 -0.03 False + within_real_lora__raw HSPC paediatric sepsis vs paediatric HC 15 4 159 / 98395 29 / 35572 13 / 22500 0 / 6000 0.08 0.06 True + within_real_lora__raw HSPC all sepsis vs all controls 61 21 545 / 408846 190 / 180632 55 / 91500 25 / 31500 0.03 -0.02 False + within_real_lora__raw Cytotoxic CD4 T adult sepsis vs adult HC 46 7 1249 / 83070 419 / 13845 347 / 17302 143 / 2637 -1.46 -3.66 True + within_real_lora__raw Cytotoxic CD4 T paediatric sepsis vs paediatric HC 15 4 71 / 17697 44 / 8125 37 / 4699 7 / 1687 -0.25 0.39 False + within_real_lora__raw Cytotoxic CD4 T all sepsis vs all controls 61 21 1320 / 100767 771 / 39446 384 / 22001 225 / 8143 -1.22 -1.28 True + within_real_lora__raw Granulocyte-like (LDG) adult sepsis vs adult HC 46 7 7960 / 310451 1041 / 59344 95 / 69000 12 / 10500 1.23 0.02 True + within_real_lora__raw Granulocyte-like (LDG) paediatric sepsis vs paediatric HC 15 4 2240 / 98395 282 / 35572 52 / 22500 4 / 6000 1.64 0.16 True + within_real_lora__raw Granulocyte-like (LDG) all sepsis vs all controls 61 21 10200 / 408846 3412 / 180632 147 / 91500 27 / 31500 0.72 0.07 True + within_real_lora__raw Platelet signal in monocytes (negative control) adult sepsis vs adult HC 46 7 11029 / 57131 1104 / 8702 1476 / 14087 96 / 1527 4.52 3.57 True + within_real_lora__raw Platelet signal in monocytes (negative control) paediatric sepsis vs paediatric HC 15 4 2974 / 15430 417 / 4363 316 / 3327 36 / 522 3.86 1.54 True + within_real_lora__raw Platelet signal in monocytes (negative control) all sepsis vs all controls 61 21 14003 / 72561 6133 / 38708 1792 / 17414 449 / 5321 2.10 2.16 True diff --git a/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_driver.log b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_driver.log new file mode 100644 index 0000000000000000000000000000000000000000..0bedcd8be3c8e23c207cdf26c0fecd3f47ff1a10 --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_driver.log @@ -0,0 +1,23 @@ +2026-10-05T23:30:32+09:00 zs_K1000: cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_finetune_intradataset_20260927/generated/ye2026_sepsis/fewshot_n5/zs__raw_all.npz +2026-10-05T23:30:51+09:00 zs_K1000: {"arm": "zs_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 979.0} +2026-10-05T23:30:51+09:00 xcalL_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/xcal_K1000.npz +2026-10-05T23:31:11+09:00 xcalL_K1000: {"arm": "xcalL_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1628.0} +2026-10-05T23:31:11+09:00 locoL_lora16sat_s26750_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_lora16sat_s26750.npz +2026-10-05T23:31:31+09:00 locoL_lora16sat_s26750_K1000: {"arm": "locoL_lora16sat_s26750_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1135.0} +2026-10-05T23:31:31+09:00 locoL_lora64sat_s59000_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_lora64sat_s59000.npz +2026-10-05T23:31:50+09:00 locoL_lora64sat_s59000_K1000: {"arm": "locoL_lora64sat_s59000_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1012.0} +2026-10-05T23:31:50+09:00 locoL_fullsat_s108500_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_fullsat_s108500.npz +2026-10-05T23:32:10+09:00 locoL_fullsat_s108500_K1000: {"arm": "locoL_fullsat_s108500_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1055.0} +2026-10-05T23:32:10+09:00 locoL_scratchsat_s50000_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_scratchsat_s50000.npz +2026-10-05T23:32:31+09:00 locoL_scratchsat_s50000_K1000: {"arm": "locoL_scratchsat_s50000_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1126.0} +2026-10-05T23:32:31+09:00 locoL_scratchsat_s100000_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_scratchsat_s100000.npz +2026-10-05T23:32:51+09:00 locoL_scratchsat_s100000_K1000: {"arm": "locoL_scratchsat_s100000_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1054.0} +2026-10-05T23:32:51+09:00 locoL_scratchsat_s150000_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_scratchsat_s150000.npz +2026-10-05T23:33:13+09:00 locoL_scratchsat_s150000_K1000: {"arm": "locoL_scratchsat_s150000_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1047.0} +2026-10-05T23:33:13+09:00 locoL_scratchsat_s162000_K1000: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_crosscohort_20261002/generated/ye2026_sepsis/hoL_ye2026_sepsis/K1000_scratchsat_s162000.npz +2026-10-05T23:33:33+09:00 locoL_scratchsat_s162000_K1000: {"arm": "locoL_scratchsat_s162000_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1040.0} +2026-10-05T23:33:33+09:00 within_lora_n5__raw: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_finetune_intradataset_20260927/generated/ye2026_sepsis/pooled/lora_n5__raw.npz +2026-10-05T23:33:51+09:00 within_lora_n5__raw: {"arm": "within_lora_n5__raw", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1785.0} +2026-10-05T23:33:51+09:00 within_real_lora__raw: ssh spark-0110 cat /home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paired_finetune_intradataset_20260927/generated/ye2026_sepsis/pooled/real_lora__raw.npz +2026-10-05T23:34:09+09:00 within_real_lora__raw: {"arm": "within_real_lora__raw", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1881.0} +2026-10-05T23:34:09+09:00 done; failed=0 diff --git a/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_locoL_fullsat_s108500_K1000.err b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_locoL_fullsat_s108500_K1000.err new file mode 100644 index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391 diff --git a/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_locoL_fullsat_s108500_K1000.log b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_locoL_fullsat_s108500_K1000.log new file mode 100644 index 0000000000000000000000000000000000000000..008fda2aa74bf7f88c2f0de8e3e508fca8d5aa5f --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261005T143721Z-rare-states-scratch-masked/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/logs/locom_extract_locoL_fullsat_s108500_K1000.log @@ -0,0 +1 @@ +{"arm": "locoL_fullsat_s108500_K1000", "sha256_ok": true, "cells": 123000, "donors": 82, "poisson_reproduced": true, "median_lib_measured": 1055.0}