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"7456573f1461a56eea75f379dbbd26a6239f76abaa9eecc82bda63dd804c8e39" + } +} diff --git a/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/per_sample_group_metrics.csv b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/per_sample_group_metrics.csv new file mode 100644 index 0000000000000000000000000000000000000000..dd08444d03981c766543bae1d38864e426706589 --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/per_sample_group_metrics.csv @@ -0,0 +1,82 @@ +arm,sample_id,n_cells,n_monocytes,n_other_label,monocyte_fraction_all_cells,monocyte_fraction_pbmc5_cells,group,subtype,c1q_high_fraction_D,n_c1q_high_D,c1q_high_fraction_A,n_c1q_high_A,c1q_high_fraction_B,n_c1q_high_B,c1q_high_fraction_C,n_c1q_high_C,meta_age,meta_condition,meta_gsm,meta_sex,meta_subtype,meta_Age,meta_CNS_involvement,meta_Erythema_nodule,meta_Gastrointestinal_involvement,meta_Genital_ulcer,meta_Ocular_involvement,meta_Oral_ulcer,meta_Sex,meta_Vascular_involvement +zsk4_raw_s13,BDU1,5000,1394,93,0.2788,0.28408396168738537,BD,BDU,0.02223816355810617,31,0.02223816355810617,31,0.0007173601147776184,1,0.005021520803443328,7,24,BD patients,GSM5951808,male,BDU,,,,,,,,, +zsk4_raw_s13,BDU2,5000,1118,101,0.2236,0.22820983874260053,BD,BDU,0.01520572450805009,17,0.01520572450805009,17,0.0008944543828264759,1,0.004472271914132379,5,30,BD patients,GSM5951809,male,BDU,,,,,,,,, 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patients,GSM5951805,male,BDV,,,,,,,,, +zsk4_raw_s13,BDV5,5000,2140,245,0.428,0.4500525762355415,BD,BDV,0.014018691588785047,30,0.014018691588785047,30,0.001869158878504673,4,0.004672897196261682,10,58,BD patients,GSM5951806,male,BDV,,,,,,,,, +zsk4_raw_s13,BDV6,5000,2107,130,0.4214,0.43264887063655033,BD,BDV,0.01945894636924537,41,0.01945894636924537,41,0.0009492168960607499,2,0.004271476032273375,9,41,BD patients,GSM5951807,male,BDV,,,,,,,,, +zsk4_raw_s13,HC1,5000,1475,48,0.295,0.297859450726979,HC,HC,0.03389830508474576,50,0.03389830508474576,50,0.0006779661016949153,1,0.006779661016949152,10,18,healthy control,GSM5951811,male,HC,,,,,,,,, +zsk4_raw_s13,HC10,5000,1188,60,0.2376,0.24048582995951417,HC,HC,0.03282828282828283,39,0.03282828282828283,39,0.0016835016835016834,2,0.011784511784511785,14,48,healthy control,GSM5951820,male,HC,,,,,,,,, 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control,GSM5951816,male,HC,,,,,,,,, +zsk4_raw_s13,HC7,5000,1013,63,0.2026,0.20518533522382013,HC,HC,0.027640671273445213,28,0.027640671273445213,28,0.0029615004935834156,3,0.007897334649555774,8,41,healthy control,GSM5951817,male,HC,,,,,,,,, +zsk4_raw_s13,HC8,5000,1132,65,0.2264,0.22938196555217832,HC,HC,0.038869257950530034,44,0.038869257950530034,44,0.00265017667844523,3,0.006183745583038869,7,36,healthy control,GSM5951818,male,HC,,,,,,,,, +zsk4_raw_s13,HC9,5000,642,44,0.1284,0.12953995157384987,HC,HC,0.045171339563862926,29,0.045171339563862926,29,0.001557632398753894,1,0.00778816199376947,5,36,healthy control,GSM5951819,male,HC,,,,,,,,, +lora3k4_raw_s13,BDU1,5000,792,40,0.1584,0.1596774193548387,BD,BDU,0.05303030303030303,42,0.05303030303030303,42,0.006313131313131313,5,0.01893939393939394,15,24,BD patients,GSM5951808,male,BDU,,,,,,,,, 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control,GSM5951820,male,HC,,,,,,,,, +lora3k4_raw_s13,HC2,5000,664,47,0.1328,0.13406016555622854,HC,HC,0.03162650602409638,21,0.03162650602409638,21,0.006024096385542169,4,0.010542168674698794,7,47,healthy control,GSM5951812,male,HC,,,,,,,,, +lora3k4_raw_s13,HC3,5000,467,28,0.0934,0.09392598551890587,HC,HC,0.02569593147751606,12,0.02569593147751606,12,0.006423982869379015,3,0.010706638115631691,5,18,healthy control,GSM5951813,male,HC,,,,,,,,, +lora3k4_raw_s13,HC4,5000,770,83,0.154,0.15659955257270694,HC,HC,0.04155844155844156,32,0.04155844155844156,32,0.003896103896103896,3,0.011688311688311689,9,53,healthy control,GSM5951814,male,HC,,,,,,,,, +lora3k4_raw_s13,HC5,5000,431,30,0.0862,0.08672032193158953,HC,HC,0.05104408352668213,22,0.05104408352668213,22,0.002320185614849188,1,0.009280742459396751,4,58,healthy control,GSM5951815,male,HC,,,,,,,,, +lora3k4_raw_s13,HC6,5000,367,20,0.0734,0.07369477911646587,HC,HC,0.02997275204359673,11,0.02997275204359673,11,0.0027247956403269754,1,0.008174386920980926,3,18,healthy control,GSM5951816,male,HC,,,,,,,,, +lora3k4_raw_s13,HC7,5000,578,44,0.1156,0.11662631154156577,HC,HC,0.02422145328719723,14,0.02422145328719723,14,0.0017301038062283738,1,0.005190311418685121,3,41,healthy control,GSM5951817,male,HC,,,,,,,,, +lora3k4_raw_s13,HC8,5000,573,34,0.1146,0.11538461538461539,HC,HC,0.03664921465968586,21,0.03664921465968586,21,0.0017452006980802793,1,0.008726003490401396,5,36,healthy control,GSM5951818,male,HC,,,,,,,,, +lora3k4_raw_s13,HC9,5000,475,41,0.095,0.09578544061302682,HC,HC,0.023157894736842106,11,0.023157894736842106,11,0.01263157894736842,6,0.01263157894736842,6,36,healthy control,GSM5951819,male,HC,,,,,,,,, +lora3k4_raw_s04,BDU1,5000,795,35,0.159,0.16012084592145015,BD,BDU,0.04654088050314465,37,0.04654088050314465,37,0.005031446540880503,4,0.016352201257861635,13,24,BD patients,GSM5951808,male,BDU,,,,,,,,, +lora3k4_raw_s04,BDU2,5000,606,15,0.1212,0.12156469408224674,BD,BDU,0.04455445544554455,27,0.04455445544554455,27,0.00825082508250825,5,0.0165016501650165,10,30,BD patients,GSM5951809,male,BDU,,,,,,,,, +lora3k4_raw_s04,BDU3,5000,866,41,0.1732,0.17463198225448678,BD,BDU,0.054272517321016164,47,0.054272517321016164,47,0.005773672055427252,5,0.018475750577367205,16,25,BD patients,GSM5951810,male,BDU,,,,,,,,, +lora3k4_raw_s04,BDV1,5000,921,30,0.1842,0.18531187122736417,BD,BDV,0.06840390879478828,63,0.06840390879478828,63,0.00760043431053203,7,0.021715526601520086,20,46,BD patients,GSM5951802,male,BDV,,,,,,,,, +lora3k4_raw_s04,BDV2,5000,800,23,0.16,0.16073940124573036,BD,BDV,0.06,48,0.06,48,0.00125,1,0.01625,13,24,BD patients,GSM5951803,male,BDV,,,,,,,,, +lora3k4_raw_s04,BDV3,5000,798,46,0.1596,0.1610819539765846,BD,BDV,0.047619047619047616,38,0.047619047619047616,38,0.0012531328320802004,1,0.010025062656641603,8,42,BD patients,GSM5951804,male,BDV,,,,,,,,, +lora3k4_raw_s04,BDV4,5000,677,18,0.1354,0.13588920112404657,BD,BDV,0.060561299852289516,41,0.060561299852289516,41,0.005908419497784343,4,0.01772525849335303,12,31,BD patients,GSM5951805,male,BDV,,,,,,,,, +lora3k4_raw_s04,BDV5,5000,938,94,0.1876,0.1911944557684468,BD,BDV,0.05863539445628998,55,0.05863539445628998,55,0.007462686567164179,7,0.015991471215351813,15,58,BD patients,GSM5951806,male,BDV,,,,,,,,, +lora3k4_raw_s04,BDV6,5000,1035,110,0.207,0.2116564417177914,BD,BDV,0.028985507246376812,30,0.028985507246376812,30,0.002898550724637681,3,0.010628019323671498,11,41,BD patients,GSM5951807,male,BDV,,,,,,,,, +lora3k4_raw_s04,HC1,5000,858,58,0.1716,0.1736139214892756,HC,HC,0.027972027972027972,24,0.027972027972027972,24,0.0,0,0.002331002331002331,2,18,healthy control,GSM5951811,male,HC,,,,,,,,, +lora3k4_raw_s04,HC10,5000,603,68,0.1206,0.12226277372262774,HC,HC,0.03648424543946932,22,0.03648424543946932,22,0.001658374792703151,1,0.011608623548922056,7,48,healthy control,GSM5951820,male,HC,,,,,,,,, +lora3k4_raw_s04,HC2,5000,667,55,0.1334,0.13488372093023257,HC,HC,0.034482758620689655,23,0.034482758620689655,23,0.0014992503748125937,1,0.01199400299850075,8,47,healthy control,GSM5951812,male,HC,,,,,,,,, +lora3k4_raw_s04,HC3,5000,478,25,0.0956,0.09608040201005025,HC,HC,0.01882845188284519,9,0.01882845188284519,9,0.0020920502092050207,1,0.0041841004184100415,2,18,healthy control,GSM5951813,male,HC,,,,,,,,, +lora3k4_raw_s04,HC4,5000,764,81,0.1528,0.15531612116283797,HC,HC,0.041884816753926704,32,0.041884816753926704,32,0.007853403141361256,6,0.02225130890052356,17,53,healthy control,GSM5951814,male,HC,,,,,,,,, +lora3k4_raw_s04,HC5,5000,424,32,0.0848,0.0853462157809984,HC,HC,0.04481132075471698,19,0.04481132075471698,19,0.009433962264150943,4,0.014150943396226415,6,58,healthy control,GSM5951815,male,HC,,,,,,,,, +lora3k4_raw_s04,HC6,5000,378,20,0.0756,0.07590361445783132,HC,HC,0.013227513227513227,5,0.013227513227513227,5,0.0,0,0.0,0,18,healthy control,GSM5951816,male,HC,,,,,,,,, +lora3k4_raw_s04,HC7,5000,577,40,0.1154,0.11633064516129032,HC,HC,0.02772963604852686,16,0.02772963604852686,16,0.0034662045060658577,2,0.005199306759098787,3,41,healthy control,GSM5951817,male,HC,,,,,,,,, +lora3k4_raw_s04,HC8,5000,565,40,0.113,0.11391129032258064,HC,HC,0.02831858407079646,16,0.02831858407079646,16,0.005309734513274336,3,0.008849557522123894,5,36,healthy control,GSM5951818,male,HC,,,,,,,,, +lora3k4_raw_s04,HC9,5000,483,39,0.0966,0.09735940334609958,HC,HC,0.024844720496894408,12,0.024844720496894408,12,0.006211180124223602,3,0.008281573498964804,4,36,healthy control,GSM5951819,male,HC,,,,,,,,, +obs,PBMC_BD_1,4719,489,325,0.10362364907819453,0.1112881201638598,BD,BD,0.08588957055214724,42,0.10429447852760736,51,0.04294478527607362,21,0.07566462167689161,37,,,,,,30.0,0,0,0,1,0,1,male,1 +obs,PBMC_BD_2,6332,946,48,0.14939987365761212,0.15054105665181414,BD,BD,0.07188160676532769,68,0.08985200845665962,85,0.03805496828752643,36,0.06342494714587738,60,,,,,,31.0,0,1,0,1,0,1,male,1 +obs,PBMC_BD_3,3519,735,101,0.20886615515771526,0.21503803393797544,BD,BD,0.05442176870748299,40,0.08435374149659863,62,0.024489795918367346,18,0.050340136054421766,37,,,,,,58.0,0,1,0,1,0,1,male,1 +obs,PBMC_BD_4,6836,1402,147,0.2050906963136337,0.20959784721184033,BD,BD,0.04065620542082739,57,0.04778887303851641,67,0.015691868758915834,22,0.02781740370898716,39,,,,,,41.0,0,1,0,1,0,1,male,1 +obs,PBMC_HC_1,2504,272,198,0.10862619808306709,0.11795316565481354,HC,HC,0.07720588235294118,21,0.10661764705882353,29,0.04411764705882353,12,0.07352941176470588,20,,,,,,30.0,/,/,/,/,/,/,female,/ +obs,PBMC_HC_2,5749,743,155,0.12923986780309618,0.13282087951376476,HC,HC,0.02557200538358008,19,0.039030955585464336,29,0.013458950201884253,10,0.02288021534320323,17,,,,,,31.0,/,/,/,/,/,/,male,/ +obs,PBMC_HC_3,6546,1306,108,0.19951115184845708,0.20285803044423734,HC,HC,0.062021439509954056,81,0.08116385911179173,106,0.027565084226646247,36,0.05359877488514548,70,,,,,,58.0,/,/,/,/,/,/,male,/ +obs,PBMC_HC_4,5619,473,89,0.08417867948033458,0.08553345388788426,HC,HC,0.040169133192389,19,0.046511627906976744,22,0.012684989429175475,6,0.02536997885835095,12,,,,,,41.0,/,/,/,/,/,/,male,/ +obs_thin_zsk4,PBMC_BD_1,4719,489,325,0.10362364907819453,0.1112881201638598,BD,BD,0.0736196319018405,36,0.0736196319018405,36,0.028629856850715747,14,0.053169734151329244,26,,,,,,30.0,0,0,0,1,0,1,male,1 +obs_thin_zsk4,PBMC_BD_2,6332,946,48,0.14939987365761212,0.15054105665181414,BD,BD,0.06025369978858351,57,0.06025369978858351,57,0.02748414376321353,26,0.039112050739957716,37,,,,,,31.0,0,1,0,1,0,1,male,1 +obs_thin_zsk4,PBMC_BD_3,3519,735,101,0.20886615515771526,0.21503803393797544,BD,BD,0.053061224489795916,39,0.053061224489795916,39,0.0163265306122449,12,0.02585034013605442,19,,,,,,58.0,0,1,0,1,0,1,male,1 +obs_thin_zsk4,PBMC_BD_4,6836,1402,147,0.2050906963136337,0.20959784721184033,BD,BD,0.026390870185449358,37,0.026390870185449358,37,0.011412268188302425,16,0.014265335235378032,20,,,,,,41.0,0,1,0,1,0,1,male,1 +obs_thin_zsk4,PBMC_HC_1,2504,272,198,0.10862619808306709,0.11795316565481354,HC,HC,0.08455882352941177,23,0.08455882352941177,23,0.03676470588235294,10,0.058823529411764705,16,,,,,,30.0,/,/,/,/,/,/,female,/ +obs_thin_zsk4,PBMC_HC_2,5749,743,155,0.12923986780309618,0.13282087951376476,HC,HC,0.02557200538358008,19,0.02557200538358008,19,0.005383580080753701,4,0.012113055181695828,9,,,,,,31.0,/,/,/,/,/,/,male,/ +obs_thin_zsk4,PBMC_HC_3,6546,1306,108,0.19951115184845708,0.20285803044423734,HC,HC,0.052833078101071976,69,0.052833078101071976,69,0.016079632465543645,21,0.027565084226646247,36,,,,,,58.0,/,/,/,/,/,/,male,/ +obs_thin_zsk4,PBMC_HC_4,5619,473,89,0.08417867948033458,0.08553345388788426,HC,HC,0.02536997885835095,12,0.02536997885835095,12,0.006342494714587738,3,0.010570824524312896,5,,,,,,41.0,/,/,/,/,/,/,male,/ +obs_thin_lora3k4,PBMC_BD_1,4719,489,325,0.10362364907819453,0.1112881201638598,BD,BD,0.07975460122699386,39,0.09611451942740286,47,0.04294478527607362,21,0.0736196319018405,36,,,,,,30.0,0,0,0,1,0,1,male,1 +obs_thin_lora3k4,PBMC_BD_2,6332,946,48,0.14939987365761212,0.15054105665181414,BD,BD,0.07293868921775898,69,0.08668076109936575,82,0.03805496828752643,36,0.06236786469344609,59,,,,,,31.0,0,1,0,1,0,1,male,1 +obs_thin_lora3k4,PBMC_BD_3,3519,735,101,0.20886615515771526,0.21503803393797544,BD,BD,0.05170068027210884,38,0.08027210884353742,59,0.02312925170068027,17,0.047619047619047616,35,,,,,,58.0,0,1,0,1,0,1,male,1 +obs_thin_lora3k4,PBMC_BD_4,6836,1402,147,0.2050906963136337,0.20959784721184033,BD,BD,0.037803138373751786,53,0.042796005706134094,60,0.015691868758915834,22,0.024964336661911554,35,,,,,,41.0,0,1,0,1,0,1,male,1 +obs_thin_lora3k4,PBMC_HC_1,2504,272,198,0.10862619808306709,0.11795316565481354,HC,HC,0.08088235294117647,22,0.10661764705882353,29,0.04411764705882353,12,0.06985294117647059,19,,,,,,30.0,/,/,/,/,/,/,female,/ +obs_thin_lora3k4,PBMC_HC_2,5749,743,155,0.12923986780309618,0.13282087951376476,HC,HC,0.024226110363391656,18,0.03768506056527591,28,0.012113055181695828,9,0.021534320323014805,16,,,,,,31.0,/,/,/,/,/,/,male,/ +obs_thin_lora3k4,PBMC_HC_3,6546,1306,108,0.19951115184845708,0.20285803044423734,HC,HC,0.062021439509954056,81,0.07886676875957122,103,0.02679938744257274,35,0.052833078101071976,69,,,,,,58.0,/,/,/,/,/,/,male,/ +obs_thin_lora3k4,PBMC_HC_4,5619,473,89,0.08417867948033458,0.08553345388788426,HC,HC,0.040169133192389,19,0.04439746300211417,21,0.012684989429175475,6,0.02536997885835095,12,,,,,,41.0,/,/,/,/,/,/,male,/ diff --git a/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/rule_summary.csv b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/rule_summary.csv new file mode 100644 index 0000000000000000000000000000000000000000..e91530653c19a992700406c0d4a0d0c4ba2c50c6 --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/rule_summary.csv @@ -0,0 +1,25 @@ +arm,rule,definition,n_monocytes,n_high,fraction_high_pooled_HC,fraction_high_pooled_BD,samples_lt20_high,hc_ties_at_threshold,library_ratio_high_over_other,ifng_response_BD_mean,ifng_response_BD_npos,ifng_response_HC_mean,ifng_response_HC_npos,proinflammatory_BD_mean,proinflammatory_BD_npos,proinflammatory_HC_mean,proinflammatory_HC_npos,phagocytosis_antigen_BD_mean,phagocytosis_antigen_BD_npos,phagocytosis_antigen_HC_mean,phagocytosis_antigen_HC_npos,phagocytosis_antigen_mhcii_fcgr_BD_mean,phagocytosis_antigen_mhcii_fcgr_BD_npos,phagocytosis_antigen_mhcii_fcgr_HC_mean,phagocytosis_antigen_mhcii_fcgr_HC_npos +zsk4_raw_s13,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.000000),25253,663,0.0334214501510574,0.02107632494372826,2/19,10238.0,1.1956519771437295,0.25454766607273543,9/9,0.16220800254549925,9/10,-0.17940093020479286,2/9,-0.23275183337911948,0/10,0.14552228560330793,7/9,0.0638040495828687,7/10,1.46467637343016,9/9,0.9646634577899839,10/10 +zsk4_raw_s13,A,>= 1 of 3 C1Q genes detected,25253,663,0.0334214501510574,0.02107632494372826,2/19,,1.1956519771437295,0.25454766607273543,9/9,0.16220800254549925,9/10,-0.17940093020479286,2/9,-0.23275183337911948,0/10,0.14552228560330793,7/9,0.0638040495828687,7/10,1.46467637343016,9/9,0.9646634577899839,10/10 +zsk4_raw_s13,B,>= 2 of 3 C1Q genes detected,25253,46,0.0020770392749244714,0.0016369961121342337,19/19,,1.3190285712010212,0.2267800471140047,6/9,0.20727283316129724,5/10,-0.08399825905326783,3/9,-0.27244104257232543,2/10,0.3484029979759466,8/9,0.18401718952112586,8/10,2.012117586626142,8/9,0.8839378640944456,7/10 +zsk4_raw_s13,C,summed C1Q UMI >= 2.0,25253,164,0.008308157099697885,0.005183821021758407,19/19,,1.259757727074011,0.16772515988463088,6/9,0.15379071900603233,7/10,-0.2980660293618522,0/9,-0.3315471541993906,0/10,0.28198360767968805,9/9,-0.019253062463837983,5/10,1.9075134891202221,9/9,0.5773747430707405,7/10 +lora3k4_raw_s13,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.000000),13196,571,0.03197925669835782,0.05208473890163271,5/19,5600.0,1.3638728328736187,0.2165317332279459,9/9,0.2535238442733919,9/10,-0.03430517877080827,3/9,-0.005699236648030928,6/10,0.23405413896627403,9/9,0.3426526359981283,10/10,1.1397210048798994,9/9,1.4203218123867771,10/10 +lora3k4_raw_s13,A,>= 1 of 3 C1Q genes detected,13196,571,0.03197925669835782,0.05208473890163271,5/19,,1.3638728328736187,0.2165317332279459,9/9,0.2535238442733919,9/10,-0.03430517877080827,3/9,-0.005699236648030928,6/10,0.23405413896627403,9/9,0.3426526359981283,10/10,1.1397210048798994,9/9,1.4203218123867771,10/10 +lora3k4_raw_s13,B,>= 2 of 3 C1Q genes detected,13196,57,0.0038029386343993088,0.004722709485899338,19/19,,1.2735683570199674,0.2878019365119162,7/9,0.20274501212190077,8/10,0.05034867730800579,5/9,-0.052591222915687186,4/10,0.27811507654112044,9/9,0.36716491941964513,10/10,1.419990438713749,9/9,1.9640185136180661,10/10 +lora3k4_raw_s13,C,summed C1Q UMI >= 2.0,13196,171,0.009161624891961971,0.01592227769531777,18/19,,1.3934073906365456,0.25259791004071913,9/9,0.3714886053058244,10/10,0.07355825108226952,8/9,0.08704750766741105,6/10,0.312150548531237,9/9,0.3963754064003884,10/10,1.298362678421569,9/9,1.7995048782553198,10/10 +lora3k4_raw_s04,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.000000),13233,564,0.03070553734690357,0.05190962883270576,6/19,5619.0,1.3258981540277177,0.17928178495772765,9/9,0.2645081028311178,7/10,0.007484257774623853,5/9,0.13833538545585658,9/10,0.21234426641915524,9/9,0.3838154092094257,10/10,0.9736261985568295,9/9,1.462647327717443,10/10 +lora3k4_raw_s04,A,>= 1 of 3 C1Q genes detected,13233,564,0.03070553734690357,0.05190962883270576,6/19,,1.3258981540277177,0.17928178495772765,9/9,0.2645081028311178,7/10,0.007484257774623853,5/9,0.13833538545585658,9/10,0.21234426641915524,9/9,0.3838154092094257,10/10,0.9736261985568295,9/9,1.462647327717443,10/10 +lora3k4_raw_s04,B,>= 2 of 3 C1Q genes detected,13233,58,0.00362256339485941,0.004975793437331899,19/19,,1.4466971930234966,0.21307283814331776,7/9,0.060634371420848925,4/8,0.0014557113971607352,4/9,-0.00952828286785451,4/8,0.27408362538215614,8/9,0.5159039813414541,8/8,1.437747528976843,8/9,1.9012337170927587,8/8 +lora3k4_raw_s04,C,summed C1Q UMI >= 2.0,13233,172,0.009315163015352769,0.015868746637977407,18/19,,1.4021513105847212,0.21488102066619677,8/9,0.2090259884467195,6/9,0.07412035690955177,6/9,0.18749321577376438,9/9,0.3285407317506593,9/9,0.4751992278706938,9/9,1.1202992146276196,9/9,1.8741651964525508,9/9 +obs,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.553161),6366,347,0.05010737294201861,0.05795072788353863,2/8,0.0,1.418190544491423,0.16993906368608175,4/4,0.21477053616162597,4/4,-0.10508480869148146,0/4,-0.19730733255337246,1/4,0.19248709802285283,4/4,0.08722185861134196,3/4,0.9111779420577537,4/4,0.6630080339583182,4/4 +obs,A,>= 1 of 3 C1Q genes detected,6366,451,0.06657122405153901,0.07418812989921612,0/8,,1.5186499015550035,0.1518249998569311,4/4,0.1708025670542706,4/4,-0.0981192454885574,0/4,-0.1819969415038049,1/4,0.165468081182499,4/4,0.08785292732519934,3/4,0.8747509840956689,4/4,0.649563440387698,4/4 +obs,B,>= 2 of 3 C1Q genes detected,6366,161,0.02290622763063708,0.02715565509518477,4/8,,1.6635700142059984,0.13036220225372416,4/4,0.18362538748309049,3/4,-0.05401180381775738,2/4,-0.15174057004100533,1/4,0.23127231122823175,4/4,0.010971722998060525,1/4,0.8552477895592911,4/4,0.5794678229797893,4/4 +obs,C,summed C1Q UMI >= 2.0,6366,292,0.04259126700071582,0.048432250839865625,2/8,,1.5971419080684228,0.18268462465457486,4/4,0.20708614197411723,4/4,-0.1166332110719507,0/4,-0.17727823944845528,1/4,0.1877075352141816,4/4,0.0741718853425958,3/4,0.9578773840053443,4/4,0.6250217552569585,4/4 +obs_thin_zsk4,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.000000),6366,292,0.04402290622763064,0.04731243001119821,2/8,2671.0,1.5810411064045988,0.30534586043186757,4/4,0.26652516595603826,4/4,-0.09476044518653086,1/4,-0.09260000223324259,2/4,0.16033236765157133,4/4,0.23269850164405032,4/4,0.9473376484718455,4/4,0.7975741204466874,4/4 +obs_thin_zsk4,A,>= 1 of 3 C1Q genes detected,6366,292,0.04402290622763064,0.04731243001119821,2/8,,1.5810411064045988,0.30534586043186757,4/4,0.26652516595603826,4/4,-0.09476044518653086,1/4,-0.09260000223324259,2/4,0.16033236765157133,4/4,0.23269850164405032,4/4,0.9473376484718455,4/4,0.7975741204466874,4/4 +obs_thin_zsk4,B,>= 2 of 3 C1Q genes detected,6366,106,0.013600572655690766,0.019036954087346025,6/8,,1.7308958184127208,0.3824235314863959,4/4,0.20342334473542187,2/4,-0.004319652632524852,2/4,-0.19175251942004007,1/4,0.16603265782519142,3/4,0.21518199825073386,4/4,0.9726848135040301,4/4,0.7517705090175393,4/4 +obs_thin_zsk4,C,summed C1Q UMI >= 2.0,6366,168,0.023622047244094488,0.02855543113101904,4/8,,1.692612369540066,0.39875069596659546,4/4,0.24022193412207002,3/4,-0.08720812458032731,1/4,0.07223167175713882,2/4,0.14868058795388514,4/4,0.2213186891481494,4/4,0.7927316852787061,4/4,0.744489538552908,4/4 +obs_thin_lora3k4,D,c1q_core score > 95th pct of pooled HC monocytes (= 0.567372),6366,339,0.05010737294201861,0.055711086226203806,2/8,0.0,1.4483611838834873,0.18194472325711547,4/4,0.28017556756765316,4/4,-0.10807149506157199,1/4,-0.14436395259144044,1/4,0.19882000267214892,4/4,0.08077711824274354,4/4,0.9086432444407357,4/4,0.6509480459793411,4/4 +obs_thin_lora3k4,A,>= 1 of 3 C1Q genes detected,6366,429,0.06478167501789549,0.06942889137737962,0/8,,1.539945453470914,0.15715328289718988,4/4,0.1825138227673539,4/4,-0.10805799650724325,0/4,-0.13903455943366008,1/4,0.17695159553793266,4/4,0.10645374542600766,3/4,0.8937834744592843,4/4,0.6717776610906977,4/4 +obs_thin_lora3k4,B,>= 2 of 3 C1Q genes detected,6366,158,0.02219040801717967,0.026875699888017916,4/8,,1.6587654587112715,0.1400575632567922,4/4,0.22848376074483967,4/4,-0.0723840070809468,1/4,-0.12495004651750903,0/4,0.21428856679000252,4/4,0.046722461702616694,2/4,0.8262146927578339,4/4,0.6074279609662666,4/4 +obs_thin_lora3k4,C,summed C1Q UMI >= 2.0,6366,281,0.04151753758052971,0.04619260918253079,3/8,,1.615013459743745,0.19121024802876138,4/4,0.26214004094406973,4/4,-0.12929143470185606,0/4,-0.14421935435370226,1/4,0.18094582634677397,4/4,0.07584893498182385,2/4,0.9499381711642236,4/4,0.6330902894248783,4/4 diff --git a/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/subtype_modules.csv b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/subtype_modules.csv new file mode 100644 index 0000000000000000000000000000000000000000..7869af6454564fdfb7e83238aadd8ae4a982cf53 --- /dev/null +++ b/paper-releases/pbisc-diffusion/updates/20261004T065028Z-behcet-c1q-k4000-corpus/diffusion/dataset/server_1/model8/plans/behcet_c1q_lora3_20261004/out/rules_groups_k4000/subtype_modules.csv @@ -0,0 +1,241 @@ +arm,rule,subtype,module,n,mean,n_pos +zsk4_raw_s13,D,BDU,ifng_response,3,0.15967101871618586,3 +zsk4_raw_s13,D,BDU,proinflammatory,3,-0.2509872888772833,1 +zsk4_raw_s13,D,BDU,phagocytosis_antigen,3,0.041517843056308366,2 +zsk4_raw_s13,D,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.6207570896754222,3 +zsk4_raw_s13,D,BDV,ifng_response,6,0.30198598975101015,6 +zsk4_raw_s13,D,BDV,proinflammatory,6,-0.14360775086854763,1 +zsk4_raw_s13,D,BDV,phagocytosis_antigen,6,0.1975245068768077,5 +zsk4_raw_s13,D,BDV,phagocytosis_antigen_mhcii_fcgr,6,1.3866360153075288,6 +zsk4_raw_s13,D,HC,ifng_response,10,0.16220800254549925,9 +zsk4_raw_s13,D,HC,proinflammatory,10,-0.23275183337911948,0 +zsk4_raw_s13,D,HC,phagocytosis_antigen,10,0.0638040495828687,7 +zsk4_raw_s13,D,HC,phagocytosis_antigen_mhcii_fcgr,10,0.9646634577899839,10 +zsk4_raw_s13,A,BDU,ifng_response,3,0.15967101871618586,3 +zsk4_raw_s13,A,BDU,proinflammatory,3,-0.2509872888772833,1 +zsk4_raw_s13,A,BDU,phagocytosis_antigen,3,0.041517843056308366,2 +zsk4_raw_s13,A,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.6207570896754222,3 +zsk4_raw_s13,A,BDV,ifng_response,6,0.30198598975101015,6 +zsk4_raw_s13,A,BDV,proinflammatory,6,-0.14360775086854763,1 +zsk4_raw_s13,A,BDV,phagocytosis_antigen,6,0.1975245068768077,5 +zsk4_raw_s13,A,BDV,phagocytosis_antigen_mhcii_fcgr,6,1.3866360153075288,6 +zsk4_raw_s13,A,HC,ifng_response,10,0.16220800254549925,9 +zsk4_raw_s13,A,HC,proinflammatory,10,-0.23275183337911948,0 +zsk4_raw_s13,A,HC,phagocytosis_antigen,10,0.0638040495828687,7 +zsk4_raw_s13,A,HC,phagocytosis_antigen_mhcii_fcgr,10,0.9646634577899839,10 +zsk4_raw_s13,B,BDU,ifng_response,3,0.10263326541520025,2 +zsk4_raw_s13,B,BDU,proinflammatory,3,-0.1405569293647776,1 +zsk4_raw_s13,B,BDU,phagocytosis_antigen,3,0.2015023627061736,2 +zsk4_raw_s13,B,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.2486585822092469,2 +zsk4_raw_s13,B,BDV,ifng_response,6,0.28885343796340696,4 +zsk4_raw_s13,B,BDV,proinflammatory,6,-0.055718923897512936,2 +zsk4_raw_s13,B,BDV,phagocytosis_antigen,6,0.42185331561083306,6 +zsk4_raw_s13,B,BDV,phagocytosis_antigen_mhcii_fcgr,6,2.39384708883459,6 +zsk4_raw_s13,B,HC,ifng_response,10,0.20727283316129724,5 +zsk4_raw_s13,B,HC,proinflammatory,10,-0.27244104257232543,2 +zsk4_raw_s13,B,HC,phagocytosis_antigen,10,0.18401718952112586,8 +zsk4_raw_s13,B,HC,phagocytosis_antigen_mhcii_fcgr,10,0.8839378640944456,7 +zsk4_raw_s13,C,BDU,ifng_response,3,-0.08451323734067241,2 +zsk4_raw_s13,C,BDU,proinflammatory,3,-0.3796846940389264,0 +zsk4_raw_s13,C,BDU,phagocytosis_antigen,3,0.25603920519808326,3 +zsk4_raw_s13,C,BDU,phagocytosis_antigen_mhcii_fcgr,3,2.02662824009221,3 +zsk4_raw_s13,C,BDV,ifng_response,6,0.2938443584972825,4 +zsk4_raw_s13,C,BDV,proinflammatory,6,-0.2572566970233153,0 +zsk4_raw_s13,C,BDV,phagocytosis_antigen,6,0.29495580892049045,6 +zsk4_raw_s13,C,BDV,phagocytosis_antigen_mhcii_fcgr,6,1.8479561136342282,6 +zsk4_raw_s13,C,HC,ifng_response,10,0.15379071900603233,7 +zsk4_raw_s13,C,HC,proinflammatory,10,-0.3315471541993906,0 +zsk4_raw_s13,C,HC,phagocytosis_antigen,10,-0.019253062463837983,5 +zsk4_raw_s13,C,HC,phagocytosis_antigen_mhcii_fcgr,10,0.5773747430707405,7 +lora3k4_raw_s13,D,BDU,ifng_response,3,0.2435707366773583,3 +lora3k4_raw_s13,D,BDU,proinflammatory,3,0.002218780592596508,1 +lora3k4_raw_s13,D,BDU,phagocytosis_antigen,3,0.2628975334394326,3 +lora3k4_raw_s13,D,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.137612374762786,3 +lora3k4_raw_s13,D,BDV,ifng_response,6,0.20301223150323966,6 +lora3k4_raw_s13,D,BDV,proinflammatory,6,-0.052567158452510664,2 +lora3k4_raw_s13,D,BDV,phagocytosis_antigen,6,0.21963244172969476,6 +lora3k4_raw_s13,D,BDV,phagocytosis_antigen_mhcii_fcgr,6,1.140775319938456,6 +lora3k4_raw_s13,D,HC,ifng_response,10,0.2535238442733919,9 +lora3k4_raw_s13,D,HC,proinflammatory,10,-0.005699236648030928,6 +lora3k4_raw_s13,D,HC,phagocytosis_antigen,10,0.3426526359981283,10 +lora3k4_raw_s13,D,HC,phagocytosis_antigen_mhcii_fcgr,10,1.4203218123867771,10 +lora3k4_raw_s13,A,BDU,ifng_response,3,0.2435707366773583,3 +lora3k4_raw_s13,A,BDU,proinflammatory,3,0.002218780592596508,1 +lora3k4_raw_s13,A,BDU,phagocytosis_antigen,3,0.2628975334394326,3 +lora3k4_raw_s13,A,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.137612374762786,3 +lora3k4_raw_s13,A,BDV,ifng_response,6,0.20301223150323966,6 +lora3k4_raw_s13,A,BDV,proinflammatory,6,-0.052567158452510664,2 +lora3k4_raw_s13,A,BDV,phagocytosis_antigen,6,0.21963244172969476,6 +lora3k4_raw_s13,A,BDV,phagocytosis_antigen_mhcii_fcgr,6,1.140775319938456,6 +lora3k4_raw_s13,A,HC,ifng_response,10,0.2535238442733919,9 +lora3k4_raw_s13,A,HC,proinflammatory,10,-0.005699236648030928,6 +lora3k4_raw_s13,A,HC,phagocytosis_antigen,10,0.3426526359981283,10 +lora3k4_raw_s13,A,HC,phagocytosis_antigen_mhcii_fcgr,10,1.4203218123867771,10 +lora3k4_raw_s13,B,BDU,ifng_response,3,0.2067496010187826,2 +lora3k4_raw_s13,B,BDU,proinflammatory,3,0.06118839249210114,2 +lora3k4_raw_s13,B,BDU,phagocytosis_antigen,3,0.2304843690076357,3 +lora3k4_raw_s13,B,BDU,phagocytosis_antigen_mhcii_fcgr,3,1.7076586149444335,3 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