Input: CONCLUSIONS: Hypersensitivity reactions to cyclosporine are due to Cremophor EL.

due

Hypersensitivity reactions to cyclosporine

Cremophor EL

Cremophor EL


Input: There are few reports in the literature related to sulfonylurea-induced hepatotoxicity.

induced

hepatotoxicity

sulfonylurea

sulfonylurea


Input: Radiation recall pneumonitis induced by gemcitabine.

induced

Radiation recall pneumonitis

gemcitabine

gemcitabine


Input: Four days after the initial injection of 3.6 mg of goserelin acetate, severe dyspnea developed due to worsening pleuritis carcinomatosa, which was considered as a flare-up.

developed

severe dyspnea

worsening pleuritis carcinomatosa

injection of 3.6 mg of goserelin acetate

injection

3.6 mg

goserelin acetate


Input: Ropinirole was added to his current therapy for Parkinson disease, with a corresponding decrease in the dose of levodopa/carbidopa to allow levodopa sparing.

added

Ropinirole

a corresponding decrease in the dose of levodopa/carbidopa to allow levodopa sparing

Ropinirole

levodopa

carbidopa

Parkinson disease

Ropinirole

levodopa

carbidopa


Input: Recognizing early signs of HMSN, such as areflexia and pes cavus deformity, can prevent severe neurotoxicity of polychemotherapy by avoiding vincristine.

by

severe neurotoxicity of polychemotherapy

vincristine

HMSN

vincristine


Input: This is the first report of pulmonary hypertension in an adult patient during lithium therapy.

during

an adult patient

adult

pulmonary hypertension

lithium therapy.

lithium


Input: In this report, we present a case of hypoglycaemic coma associated with SP, an adverse reaction that is likely to be underreported and expected to occur with greater frequency as the use of SP increases.

associated

hypoglycaemic coma

an adverse reaction that is likely to be underreported and expected to occur with greater frequency as the use of SP increases

SP

SP


Input: However, we have recently had four cases of clofibrate-induced myopathy in patients with diabetes insipidus due to hypothalamic lesions.

induced

four cases

diabetes insipidus due to hypothalamic lesions

four

myopathy

clofibrate

clofibrate

diabetes insipidus


Input: One patient had MRI T2 abnormalities compatible with cyclosporin neurotoxicity.

had

One patient

One

neurotoxicity

MRI T2 abnormalities

cyclosporin

cyclosporin


Input: Post-exposure prophylaxis for H1N1 with oseltamivir in renal allograft recipient--safe and effective without any immunosuppresive drug interaction.

Post-exposure prophylaxis

renal allograft recipient

renal allograft

safe and effective without any immunosuppresive drug interaction

oseltamivir

oseltamivir


Input: Seven days after the introduction of amoxycillin (500 mg/8 h) for a probable respiratory infection, the patient developed spontaneous bruising, with an INR of 7.1.

developed

the patient

spontaneous bruising, with an INR of 7.1

Seven days after the introduction of amoxycillin (500 mg/8 h)

a probable respiratory infection

Seven days after

amoxycillin

500 mg/8 h


Input: To report a case in which significant hypotension occurred after initiation of tizanidine in a patient using the antihypertensive agent lisinopril.

after

a patient

a case

hypotension

initiation of tizanidine

lisinopril

lisinopril

tizanidine


Input: We herein describe a case of severe hyponatremia complicated by seizure and coma due to the intake of non-steroidal anti-inflammatory drugs (NSAIDs) in a patient on DDAVP replacement therapy for central diabetes insipidus (DI).

due to

a patient

for central diabetes insipidus (DI)

severe hyponatremia

seizure and coma

intake of non-steroidal anti-inflammatory drugs (NSAIDs)

on DDAVP replacement therapy

non-steroidal anti-inflammatory drugs

DDAVP

central diabetes insipidus

DDAVP

non-steroidal anti-inflammatory drugs


Input: Each subject was treated according to the following sequence: baseline; phase 1 (days 1-6): cisapride 10 mg 4 times/day; washout (days 7-13); phase 2 (days 14-44): fluoxetine 20 mg/day; and phase 3 (days 45-52): cisapride 10 mg 4 times/day (days 45-51) plus fluoxetine 20 mg/day (days 45-52).

treated

Each subject

baseline; phase 1 (days 1-6): cisapride 10 mg 4 times/day; washout (days 7-13); phase 2 (days 14-44): fluoxetine 20 mg/day; and phase 3 (days 45-52): cisapride 10 mg 4 times/day (days 45-51) plus fluoxetine 20 mg/day (days 45-52)

cisapride

fluoxetine

cisapride

fluoxetine

10 mg

20 mg/day

10 mg

20 mg/day

4 times/day

4 times/day

cisapride

fluoxetine


Input: These findings are consistent with an immune-complex form of glomerulopathy in which gold is neither the antigen nor a hapten in the glomerular deposits, and they suggest the hypothesis that antibodies to tubular epithelial antigens induced by gold therapy may be a causative factor in the renal disease associated with gold therapy in rheumatoid arthritis.

associated

renal disease

gold therapy in rheumatoid arthritis

gold

rheumatoid arthritis


Input: Induction of rapid mood cycling during L-dopa treatment in a bipolar patient.

during

a bipolar patient

rapid mood cycling

L-dopa

L-dopa

bipolar


Input: To report a patient having a first-time seizure after receiving venlafaxine and trimipramine for depression.

receiving

patient

seizure

venlafaxine and trimipramine

venlafaxine

trimipramine

depression

venlafaxine

trimipramine


Input: Paraplegia following prophylactic intrathecal cytosine arabinoside (Ara-C) is described in a patient with acute myelogenous leukemia in remission who received doses of 100 mg/m2/d for 5 consecutive days.

following

a patient with acute myelogenous leukemia in remission

Paraplegia

prophylactic intrathecal cytosine arabinoside (Ara-C)

doses of 100 mg/m2/d for 5 consecutive days

cytosine arabinoside

intrathecal

acute myelogenous leukemia in remission

100 mg/m2/d

5 consecutive days


Input: Isoniazid induced gynaecomastia: a case report.

induced

gynaecomastia

Isoniazid

Isoniazid


Input: One previous study of four transplant patients whose immediate post-transplantation immunosuppression utilized corticosteroids, cyclosporine, MMF, and anti-T-lymphocyte globulin noted anemia in 13% of them.

noted

four transplant patients

four

transplant

anemia

immediate post-transplantation immunosuppression utilized corticosteroids, cyclosporine, MMF, and anti-T-lymphocyte globulin

corticosteroids

cyclosporine

MMF

anti-T-lymphocyte globulin

post-transplantation immunosuppression

corticosteroids

cyclosporine

MMF

anti-T-lymphocyte globulin


Input: Pleuropulmonary changes during treatment of Parkinson's disease with a long-acting ergot derivative, cabergoline.

during

Pleuropulmonary changes

cabergoline

Parkinson's disease

cabergoline


Input: However, each infant demonstrated hemodynamic decompensation shortly after verapamil administration and required cardiopulmonary resuscitation.

demonstrated

each infant

infant

hemodynamic decompensation

verapamil

verapamil


Input: Long-term studies are needed to determine whether the insulin-sensitizing effects of the glitazones can prevent or delay premature atherosclerotic cardiovascular disease, morbidity, and death.

prevent

glitazones

premature atherosclerotic cardiovascular disease, morbidity, and death

glitazones


Input: Probable propafenone-induced transient global amnesia.

induced

transient global amnesia

propafenone

propafenone


Input: The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen.

have

fever and autonomic instability without evidence of infection which entirely resolved

24 hours of reinstitution of full preadmission dosing of oral baclofen

oral

baclofen

24 hours


Input: Traumatic late flap dehiscence and Enterobacter keratitis following LASIK.

following

Traumatic late flap dehiscence and Enterobacter keratitis

LASIK

LASIK


Input: We report on a patient with subarachnoid haemorrhage who developed an acute life-threatening pseudo-obstruction of the colon, a variant of adynamic ileus, while being treated with intravenous nimodipine.

developed

patient with subarachnoid haemorrhage

pseudo-obstruction of the colon

intravenous nimodipine

subarachnoid haemorrhage

nimodipine

intravenous


Input: A 73-year-old woman presented with fever and cough 2 weeks after completing the third cycle of fludarabine for chronic lymphocytic leukemia (CLL).

presented

A 73-year-old woman

woman

fever and cough

2 weeks after completing the third cycle of fludarabine for chronic lymphocytic leukemia (CLL)

chronic lymphocytic leukemia (CLL)

2 weeks

fludarabine


Input: We report a case of myoclonus induced by quetiapine.

induced

a case

myoclonus

quetiapine

quetiapine


Input: A 21-year-old woman suffering from bipolar affective disorder developed systemic lupus erythematosus (SLE) with characteristic laboratory findings, 18 months after starting carbamazepine maintenance treatment.

developed

A 21-year-old woman suffering from bipolar affective disorder

woman

systemic lupus erythematosus (SLE)

18 months after starting carbamazepine maintenance treatment

bipolar affective disorder

18 months

carbamazepine


Input: Acyclovir produces neurologic symptoms that resemble extension of viral infection into the central nervous system.

produces

neurologic symptoms

Acyclovir

Acyclovir


Input: Subcutaneous IL-2 is safe and well tolerated, with a mortality rate <3%.

with

mortality rate <3%

Subcutaneous IL-2

Subcutaneous


Input: Two patients with HLH developed etoposide-related secondary acute myeloid leukemia (sAML) following therapy for HLH.

related

Two patients with HLH

Two

secondary acute myeloid leukemia (sAML)

etoposide

HLH

etoposide


Input: We report a case of secondary glaucoma caused by epithelial downgrowth in which filtration surgery was performed with adjunctive use of subconjunctival 5-fluorouracil.

caused

secondary glaucoma

epithelial downgrowth

filtration surgery was performed with adjunctive use of subconjunctival 5-fluorouracil

subconjunctival


Input: Mild serotonin syndrome associated with concurrent linezolid and fluoxetine.

associated

serotonin syndrome

concurrent linezolid and fluoxetine

linezolid

fluoxetine

linezolid

fluoxetine


Input: Risperidone versus clozapine in the treatment of psychosis in six patients with Parkinson's disease and other akinetic-rigid syndromes.

treatment

six patients with Parkinson's disease and other akinetic-rigid syndromes

six

Parkinson's disease

akinetic-rigid syndromes

Risperidone versus clozapine

Risperidone

clozapine

psychosis


Input: Hydroxyurea associated with concomitant occurrence of diffuse longitudinal melanonychia and multiple squamous cell carcinomas in an elderly subject.

associated

an elderly subject

elderly

concomitant occurrence of diffuse longitudinal melanonychia and multiple squamous cell carcinomas

Hydroxyurea

Hydroxyurea


Input: Women (aged < or = 75 yr; > or = 2 yr since their last menstrual period) received placebo, RLX 60 mg/d, ALN 10 mg/d, or RLX 60 mg/d and ALN 10 mg/d combined.

received

Women (aged < or = 75 yr; > or = 2 yr since their last menstrual period)

Women

aged < or = 75 yr; > or = 2 yr

RLX 60 mg/d, ALN 10 mg/d, or RLX 60 mg/d and ALN 10 mg/d combined

60 mg/d

10 mg/d

60 mg/d

10 mg/d

RLX

ALN

RLX

ALN

ALN

RLX


Input: Myoclonus and seizures in a patient with parkinsonism: induction by levodopa and its confirmation on SEPs.

induction

a patient with parkinsonism

Myoclonus and seizures

levodopa

parkinsonism

levodopa


Input: OBJECTIVE: To describe a probable case of transient global amnesia caused by propafenone.

caused

transient global amnesia

propafenone

propafenone


Input: We report the development of squamous-cell carcinoma within a basal-cell epithelioma that was treated with intralesional injections of 5-FU.

treated

squamous-cell carcinoma within a basal-cell epithelioma

intralesional injections of 5-FU

intralesional injections


Input: This case report illustrates the use of continuous high-dose intracoronary nitroglycerin infusion through a 6 French coronary guiding catheter in the treatment of a patient with cocaine-induced refractory coronary vasospasm.

induced

refractory coronary vasospasm

cocaine

cocaine


Input: Here, we describe levofloxacin-induced delirium with psychotic features in a relatively young, otherwise healthy female.

induced

relatively young, otherwise healthy female

delirium with psychotic features

levofloxacin

levofloxacin


Input: Ticlopidine-induced phenytoin toxicity.

induced

toxicity

Ticlopidine

Ticlopidine

phenytoin

phenytoin

Ticlopidine


Input: Pancreatitis has been associated with the tetracycline class of antibiotics and concerns about tigecycline-induced acute pancreatitis have recently been raised.

induced

acute pancreatitis

tigecycline

tigecycline


Input: Abrupt, accidental withdrawal of trihexyphenidyl triggered severe exacerbation of the cranial dystonia associated with inspiratory stridor and acute respiratory difficulties, prompting emergency admission.

triggered

exacerbation of the cranial dystonia associated with inspiratory stridor and acute respiratory difficulties

Abrupt, accidental withdrawal of trihexyphenidyl

trihexyphenidyl


Input: We report two patients with anhedonic ejaculation (ejaculation without orgasm) associated with initiation of treatment with desipramine.

associated

two patients

two

anhedonic ejaculation (ejaculation without orgasm)

desipramine

desipramine


Input: We describe longitudinal diffusion-weighted MRI findings of sub-acute leukoencephalopathy following methotrexate therapy in a 24-year-old man diagnosed with pre-B-cell acute lymphoblastic leukemia (ALL), presenting with right-sided paralysis and aphasia after second consolidation with intrathecal triple-drug therapy given intrathecally.

following

a 24-year-old man

man

longitudinal diffusion-weighted MRI findings of sub-acute leukoencephalopathy

methotrexate

methotrexate


Input: Therefore, although garenoxacin reportedly causes fewer adverse reactions for cardiac rhythms than third-generation quinolone antibiotics, one must be cautious of the interference of other drugs during hypokalemia in order to prevent TdP.

causes

adverse reactions for cardiac rhythms

garenoxacin

garenoxacin


Input: A 45-year-old woman with steroid-dependent Crohn's colitis, successfully managed with maintenance infliximab infusions and methotrexate, developed a lupus-like syndrome eight months after her initial infusion.

developed

A 45-year-old woman with steroid-dependent Crohn's colitis

woman

lupus-like syndrome

maintenance infliximab infusions and methotrexate

eight months after her initial infusion

eight months

infliximab

methotrexate

infusions

steroid-dependent Crohn's colitis

infliximab

methotrexate


Input: Severe neurotoxicity with methyl G: CALGB experience.

with

neurotoxicity

methyl G

methyl G


Input: We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy.

developed

60-year-old woman affected by squamous lung carcinoma

woman

paroxysmal supraventricular tachycardia

cisplatin and etoposide combination

cisplatin

etoposide

squamous lung carcinoma,

etoposide

cisplatin


Input: The authors report a case of acute pancreatitis (AP) occurring in a patient under treatment with carbamazepine (CBZ) for post-traumatic petit mal epilepsy, and review the current literature of drug-induced AP.

occurring

a patient

acute pancreatitis

carbamazepine

post-traumatic petit mal epilepsy

carbamazepine


Input: Acute ocular ischemic change may be associated with intravitreal injection of bevacizumab in patients with vascular compromised diabetic retinopathy and/or underlying stenosis of the carotid artery.

associated

patients with vascular compromised diabetic retinopathy and/or underlying stenosis of the carotid artery

vascular compromised diabetic retinopathy

underlying stenosis of the carotid artery

Acute ocular ischemic change

intravitreal injection of bevacizumab

bevacizumab

intravitreal injection


Input: All-trans-retinoic acid (ATRA) has been proved to be an effective treatment for acute promyelocytic leukemia (APL), inducing remission in more than 90% of cases.

proved

more than 90% of cases

more than 90%

All-trans-retinoic acid (ATRA)

acute promyelocytic leukemia (APL)

All-trans-retinoic acid


Input: Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus.

associated

Vanishing bile duct and Stevens-Johnson syndrome

ciprofloxacin

ciprofloxacin


Input: Antiasthmatic medications were prescribed, but the asthma symptoms did not improve.

improve.

Antiasthmatic medications were prescribed

asthma

Antiasthmatic medications


Input: Both 6-MP and AZA are widely used and are known to cause hepatotoxicity in a proportion of patients.

used

a proportion of patients

hepatotoxicity

6-MP and AZA

AZA

AZA


Input: Both raloxifene (RLX) and alendronate (ALN) can treat and prevent new vertebral fractures, increase bone mineral density (BMD), and decrease biochemical markers of bone turnover in postmenopausal women with osteoporosis.

treat

postmenopausal women with osteoporosis

osteoporosis

increase bone mineral density (BMD)

decrease biochemical markers of bone turnover

Both raloxifene (RLX) and alendronate (ALN)

vertebral fractures

raloxifene

alendronate


Input: We report a case of severe respiratory failure due to gold salt toxicity in a patient suffering from rheumatoid arthritis requiring mechanical ventilation.

due

a patient suffering from rheumatoid arthritis

respiratory failure

gold salt

rheumatoid arthritis

gold


Input: We describe rupture of a cerebral arterial aneurysm in a 32 year old hypertensive woman following the introduction of nifedipine treatment.

following

a 32 year old hypertensive woman

32 year old

woman

rupture of a cerebral arterial aneurysm

nifedipine treatment

hypertensive

nifedipine


Input: Factors that suggested an association between the severe angioedematous reaction and BP topical application include the strong reaction to BP in the patch-test, the temporal relationship, the complete resolution of symptoms after the drug was withdrawn and the absence of other identified explanations.

association

severe angioedematous reaction

BP topical application

BP topical application


Input: RLX+ALN reduced bone turnover more than either drug alone, resulting in greater BMD increment, but whether this difference reflects better fracture risk reduction was not assessed in this study.

reduced

bone turnover more than either drug alone, resulting in greater BMD increment

RLX+ALN

RLX+ALN

RLX+ALN

RLX+ALN

RLX+ALN

RLX+ALN


Input: Hepatotoxicity related to itraconazole: report of three cases.

related

three cases

three

Hepatotoxicity

itraconazole

itraconazole


Input: This report presents a case of colon perforation which occurred 4 months after treatment with intraperitoneal chromic phosphate for stage IB ovarian papillary serous cystadenocarcinoma.

occurred

colon perforation

intraperitoneal chromic phosphate

chromic phosphate

4 months

intraperitoneal

stage IB ovarian papillary serous cystadenocarcinoma


Input: Flutamide withdrawal syndrome is characterized by a decrease in prostate-specific antigen (PSA) after flutamide withdrawal in a subset of patients with progressing metastatic carcinoma of the prostate.

withdrawal

subset of patients with progressing metastatic carcinoma of the prostate

decrease in prostate-specific antigen (PSA)

flutamide

progressing metastatic carcinoma of the prostate

flutamide


Input: Bradycardia and congestive heart failure associated with ocular timolol maleate.

associated

Bradycardia and congestive heart failure

ocular timolol maleate

ocular

timolol maleate


Input: CONCLUSIONS: Patients receiving intravitreal injections of bevacizumab should be evaluated for potential systemic risk factors such as carotid insufficiency, coagulopathy and poorly controlled diabetes mellitus.

risk

carotid insufficiency, coagulopathy and poorly controlled diabetes mellitus

intravitreal injections of bevacizumab

bevacizumab

intravitreal injections


Input: Severe serotonin toxicity may result from metaxalone abuse in individuals using a selective serotonin reuptake inhibitor therapeutically.

result

serotonin toxicity

metaxalone abuse

using a selective serotonin reuptake inhibitor therapeutically

metaxalone

selective serotonin reuptake inhibitor

abuse

metaxalone

selective serotonin reuptake inhibitor


Input: The purpose of this article is to present the first case-series of posterior reversible encephalopathy syndrome (PRES) associated with L-asparaginase treatment.

associated

posterior reversible encephalopathy syndrome (PRES)

L-asparaginase treatment

L-asparaginase


Input: Eruptive epidermoid cysts resulting from treatment with imiquimod.

resulting

Eruptive epidermoid cysts

imiquimod

imiquimod


Input: Carbamazepine-related hyponatremia following cardiopulmonary bypass.

related

hyponatremia

Carbamazepine

Carbamazepine


Input: Fulminant hepatic failure is a rare complication of disulfiram treatment for alcoholism.

complication

Fulminant hepatic failure

disulfiram

alcoholism

disulfiram


Input: Implications: Clinicians should be aware of the possibility of increased toxicity of ropivacaine when used together with inhibitors of CYP1A2.

increased

toxicity

ropivacaine

inhibitors of CYP1A2

ropivacaine

inhibitors of CYP1A2

inhibitors of CYP1A2

ropivacaine


Input: Evidence obtained indicated that the Reye-like syndrome might be caused by calcium hopantenate possibly due to the induction of pantothenic acid deficiency.

caused

Reye-like syndrome

calcium hopantenate

calcium hopantenate


Input: Hepatopathy subsided after the cessation of carbamazepine and lynestrenol.

after

Hepatopathy subsided

carbamazepine

lynestrenol

cessation

carbamazepine

lynestrenol

lynestrenol

carbamazepine


Input: This article presents a patient with hypoparathyroidism who was treated with calcium carbonate and calcitriol resulting in two admissions to the hospital for milk-alkali syndrome.

resulting

a patient with hypoparathyroidism

two admissions to the hospital for milk-alkali syndrome

calcium carbonate and calcitriol

hypoparathyroidism

calcium carbonate

calcitriol

calcium carbonate

calcitriol


Input: Recurrent hyponatremia associated with citalopram and mirtazapine.

associated

Recurrent hyponatremia

citalopram and mirtazapine

citalopram

mirtazapine


Input: A case report of a sharp rise in International Normalized Ratio (INR) values during a patient's concomitant use of warfarin and the antineoplastic agent vismodegib is presented.

during

a patient

a sharp rise in International Normalized Ratio (INR) values

concomitant use of warfarin and the antineoplastic agent vismodegib

warfarin

vismodegib

warfarin

vismodegib


Input: In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.

developed

a case of juvenile idiopathic arthritis patient

juvenile

thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms

Etanercept

idiopathic arthritis

Etanercept


Input: A 52-year-old woman developed symmetric sensorimotor polyneuropathy and cerebellar syndrome after 24 months of amiodarone treatment.

developed

A 52-year-old woman

woman

symmetric sensorimotor polyneuropathy

cerebellar syndrome

amiodarone

24 months

amiodarone


Input: The case of a patient under tibolone therapy for two years who developed a mixed-type liver injury with prolonged cholestasis and features of the vanishing bile duct syndrome following a ten weeks treatment with St. John wort (Hypericum Perforatum) infusions is reported.

developed

a patient under tibolone therapy

a mixed-type liver injury with prolonged cholestasis and features of the vanishing bile duct syndrome

under tibolone therapy

a ten weeks treatment with St. John wort (Hypericum Perforatum) infusions

Hypericum Perforatum

tibolone

infusions

ten weeks

tibolone

Hypericum Perforatum


Input: OBJECTIVE: To report a case of a diffuse papular eruption following treatment of psoriasis with methotrexate injections.

following

diffuse papular eruption

methotrexate injections

methotrexate

injections

psoriasis


Input: Prolonged severe 5-fluorouracil-associated neurotoxicity in a patient with dihydropyrimidine dehydrogenase deficiency.

associated

a patient with dihydropyrimidine dehydrogenase deficiency

neurotoxicity

dihydropyrimidine dehydrogenase deficiency


Input: Life-threatening interstitial lung disease associated with trastuzumab: case report.

associated

case

Life-threatening interstitial lung disease

trastuzumab

trastuzumab


Input: Thalidomide neuropathy is often associated with proximal weakness and may progress even after discontinuation of treatment, in the phenomenon of 'coasting'.

associated

neuropathy

proximal weakness

Thalidomide

Thalidomide


Input: RESULTS: Our patient developed Crohn's disease while on Copaxone treatment as a consequence of long-term immunosuppression.

developed

patient

Crohn's disease

long-term immunosuppression

Copaxone

Copaxone


Input: Acute vision loss after intravitreal injection of bevacizumab (avastin) associated with ocular ischemic syndrome.

after

Acute vision loss

ocular ischemic syndrome

intravitreal injection of bevacizumab (avastin)

intravitreal injection

bevacizumab


Input: Development of persistent late onset asthma following treatment with captopril.

following

persistent late onset asthma

captopril

captopril


Input: Herein, we describe a patient with AIDS who presented to medical attention with pancytopenia 48 months postchemotherapy with etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (R-EPOCH) for diffuse large B-cell lymphoma.

presented

a patient with AIDS

AIDS

medical attention with pancytopenia

48 months postchemotherapy with etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (R-EPOCH)

diffuse large B-cell lymphoma

48 months

etoposide

prednisone

vincristine

cyclophosphamide

doxorubicin

rituximab

etoposide

prednisone

vincristine

cyclophosphamide

doxorubicin

rituximab


Input: However, prolongation of 5-FU half-life and an increase in INR have been reported with the concurrent use of 5-FU and warfarin.

reported

prolongation of 5-FU half-life and an increase in INR

the concurrent use of 5-FU and warfarin

warfarin

warfarin


Input: Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C.

during

Graves' hyperthyroidism following transient thyrotoxicosis

interferon

interferon

chronic hepatitis type C.


Input: We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.

attributed

a 50-year-old woman

woman

acute generalized exanthematous pustulosis (AGEP)

ingestion of nimesulide

nimesulide

ingestion


Input: This case demonstrates the value of DWI in evaluation and diagnosis of sub-acute toxic leukoencephalopathy in patients being treated with methotrexate.

in

patients

sub-acute toxic leukoencephalopathy

methotrexate

methotrexate


Input: We report the first histopathologically documented case of oral mucosa pigmentation after OLP treatment with topical tacrolimus.

treatment

oral mucosa pigmentation

topical tacrolimus

tacrolimus

OLP

topical


Input: Progressive hypoxemia mandated endotracheal intubation 1 week after rituximab administration and led to death 4 weeks after admission.

after

Progressive hypoxemia

led to death

rituximab administration

rituximab

1 week


Input: Angiotensin converting enzyme blockers and their influence on the endothelial dysfunction, but the risk of hyperpotassemia are showed.

showed.

hyperpotassemia

Angiotensin converting enzyme blockers

Angiotensin converting enzyme blockers


Input: This is the first report of a fatal outcome from serotonin toxicity, precipitated by an interaction between methylene blue and venlafaxine.

precipitated

serotonin toxicity

methylene blue

venlafaxine

methylene blue

venlafaxine

methylene blue

venlafaxine


Input: A helicoidal CT scan showed diffuse and severe interstitial pneumonitis, and lung biopsy confirmed accelerated usual interstitial pneumonia consistent with drug-induced toxicity.

induced

diffuse and severe interstitial pneumonitis

accelerated usual interstitial pneumonia

toxicity

drug

drug


Input: We report a case of severe hypotension associated with intravenous valproate used to treat status epilepticus in an 11-year-old girl.

associated

an 11-year-old girl

girl

hypotension

intravenous valproate

status epilepticus

intravenous

valproate


Input: Relief by naloxone of morphine-induced spasm of the sphincter of Oddi in a post-cholecystectomy patient.

Relief

post-cholecystectomy patient.

naloxone

morphine-induced spasm of the sphincter of Oddi

naloxone


Input: The results of the ultrasound examination combined with clinical anamnesis allowed diagnosis of gastric mucosa foveolar hyperplasia due to prolonged PGE1 therapy.

due

gastric mucosa foveolar hyperplasia

prolonged PGE1 therapy

prolonged


Input: To our knowledge, no prior cases of penicillamine-induced TTP in RA have been reported.

induced

TTP

penicillamine

penicillamine


Input: Alternating sinus rhythm and intermittent sinoatrial block induced by propranolol.

induced

Alternating sinus rhythm and intermittent sinoatrial block

propranolol

propranolol


Input: The noted increase in the theophylline level after zafirlukast administration is in contrast to the original reports by the manufacturer.

after

increase in the theophylline level

zafirlukast administration

zafirlukast


Input: The cause is presumed to be secondary to hypercoagulability due to asparaginase-induced antithrombin III deficiency.

induced

antithrombin III deficiency

asparaginase

asparaginase


Input: Troglitazone-induced fulminant hepatic failure.

induced

fulminant hepatic failure

Troglitazone

Troglitazone


Input: A sixty-year-old woman with advanced breast cancer, previously treated with cisplatin, developed an irreversible lethal renal failure with anuria, the day after 5 g/m2 bolus ifosfamide.

developed

A sixty-year-old woman with advanced breast cancer, previously treated with cisplatin

sixty-year-old

woman

an irreversible lethal renal failure with anuria

the day after 5 g/m2 bolus ifosfamide

advanced breast cancer

the day after

5 g/m2

ifosfamide


Input: With the negative viral serologies, the clinical picture was most consistent with an infectious mononucleosis-like syndrome produced by the minocycline ingestion.

produced

infectious mononucleosis-like syndrome

minocycline ingestion

ingestion

minocycline


Input: High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer.

after

High-grade endometrial stromal sarcoma

tamoxifen

tamoxifen

breast cancer


Input: We report here two cases of dyserythropoietic anaemia associated with long-term linezolid use that share striking similarities to chloramphenicol-associated myelotoxicity.

associated

dyserythropoietic anaemia

long-term linezolid

linezolid

long-term


Input: Dipyrone-induced granulocytopenia: a case for awareness.

induced

a case

granulocytopenia

Dipyrone

Dipyrone


Input: We report the case of a patient with chronic hepatitis C infection who developed severe anaemia during antiviral treatment with peginterferon alfa/ribavirin when oseltamivir was added to treat influenza.

developed

a patient with chronic hepatitis C infection

severe anaemia

peginterferon alfa/ribavirin

oseltamivir

chronic hepatitis C infection

influenza

peginterferon alfa

ribavirin

oseltamivir

peginterferon alfa

ribavirin

oseltamivir


Input: Both patients were then treated with a carboplatin alternative to cisplatin in the following courses, which resulted in neither a relapse of the colitis nor a recurrence of the malignancies up to this time.

resulted

Both patients

neither a relapse of the colitis nor a recurrence of the malignancies

carboplatin

carboplatin

colitis

malignancies


Input: It is rare to develop simultaneous toxicities while on anticonvulsants.

develop

toxicities

anticonvulsants

anticonvulsants


Input: Because of serious side effects of an increase in the QT interval causing torsades de pointes, dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting.

increase

QT interval causing torsades de pointes

dofetilide

dofetilide


Input: It should be emphasized that the recurrence of nephrotic syndrome was observed after the following chemotherapy, including M-CSF, whereas the bone marrow still remained completely remitted.

after

nephrotic syndrome

the bone marrow still remained completely remitted

chemotherapy, including M-CSF

M-CSF


Input: We present a patient with human immunodeficiency virus infection under treatment with foscarnet for CMV retinitis who complained of thirst and polyuria.

complained

a patient with human immunodeficiency virus infection

human immunodeficiency virus infection

thirst and polyuria

foscarnet

CMV retinitis

foscarnet


Input: This represents the first report of nonconvulsive status epilepticus induced by ifosfamide.

induced

nonconvulsive status epilepticus

ifosfamide

ifosfamide


Input: BACKGROUND: Headaches have been reported as a potential side effect of capecitabine therapy.

of

Headaches

capecitabine

capecitabine


Input: When DSCG was withdrawn, urticaria vanished and the child remained symptom-free.

remained

the child

child

urticaria vanished

symptom-free

DSCG was withdrawn

DSCG


Input: Hepatotoxic effects in a child receiving valproate and carnitine.

receiving

a child

child

Hepatotoxic effects

valproate and carnitine

valproate

carnitine

valproate

carnitine


Input: We report a case of Graves' hyperthyroidism induced by long-term interferon (IFN) therapy.

induced

a case

Graves' hyperthyroidism

long-term interferon (IFN) therapy

long-term

interferon


Input: Bleomycin and cyclophosphamide toxicity simulating metastatic nodules to the lungs in childhood cancer.

simulating

childhood cancer

childhood

metastatic nodules to the lungs

Bleomycin and cyclophosphamide toxicity

cancer

Bleomycin

cyclophosphamide

cyclophosphamide

Bleomycin


Input: The patient presented with fulminant microangiopathic hemolytic anemia and thrombocytopenia within 48 hr of initiating therapy with trimethoprim-sulfamethoxazole.

presented

The patient

fulminant microangiopathic hemolytic anemia and thrombocytopenia

within 48 hr of initiating therapy with trimethoprim-sulfamethoxazole

48 hr

trimethoprim

sulfamethoxazole

trimethoprim

sulfamethoxazole


Input: Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.

taking

asthmatic patients

Pneumocystis pneumonia

fever, pulmonary infiltrates, and hypoxia

methotrexate

methotrexate

asthmatic


Input: Acute respiratory distress syndrome after rituximab infusion.

after

Acute respiratory distress syndrome

rituximab infusion

rituximab

infusion


Input: CONCLUSION: Gemcitabine-induced recall pneumonitis is a rarely reported phenomenon and should be taken into account even after extended time interval to the previous radiotherapy.

induced

recall pneumonitis

Gemcitabine

Gemcitabine


Input: In a 61-year-old man receiving chronic low-dosage amiodarone an interstitial pneumopathy was observed.

observed.

a 61-year-old man

man

interstitial pneumopathy

chronic low-dosage amiodarone

amiodarone

low-dosage


Input: A 75-year-old man developed bilateral lower leg edema 6 months after switching from troglitazone to pioglitazone.

developed

A 75-year-old man

man

bilateral lower leg edema

6 months after switching from troglitazone to pioglitazone

pioglitazone

6 months

troglitazone


Input: An acute ischaemic event associated with the use of venlafaxine: a case report and proposed pathophysiological mechanisms.

associated

a case

An acute ischaemic event

venlafaxine

venlafaxine


Input: Oseltamivir was effective for post-exposure prophylaxis of H1N1 in close contact.

post-exposure prophylaxis

Oseltamivir

Oseltamivir


Input: Herein, we present a patient with severe and prolonged hypoglycemia after long-acting octreotide treatment.

after

a patient

severe and prolonged hypoglycemia

long-acting octreotide treatment

octreotide


Input: Worsening pneumonitis due to a pharmacokinetic drug-drug interaction between everolimus and voriconazole in a renal transplant patient.

due to

a renal transplant patient

Worsening pneumonitis

pharmacokinetic drug-drug interaction between everolimus and voriconazole

everolimus

voriconazole

renal transplant

everolimus

voriconazole


Input: Vocal cord paralysis as a consequence of peritonsillar infiltration with bupivacaine.

consequence

Vocal cord paralysis

peritonsillar infiltration with bupivacaine

peritonsillar infiltration

bupivacaine


Input: The sulfonamides are the best verified drug-trigger for erythema multiforme and Stevens-Johnson syndrome.

drug-trigger

erythema multiforme and Stevens-Johnson syndrome

sulfonamides

sulfonamides


Input: Edema associated with ibuprofen therapy.

associated

Edema

ibuprofen

ibuprofen


Input: A patient is presented with typical hyperthyroidism, who developed a severe proximal muscle weakness and a raised creatine phosphokinase after treatment for hyperthyroidism with propylthiouracil (100 mg orally, three times a day).

after

A patient is presented with typical hyperthyroidism

severe proximal muscle weakness and a raised creatine phosphokinase

treatment for hyperthyroidism with propylthiouracil (100 mg orally, three times a day)

hyperthyroidism

typical hyperthyroidism

propylthiouracil

100 mg

orally

three times a day


Input: Atorvastatin is the most potent of this class of agents currently available and is commonly used in the treatment of hyperlipidemia.

treatment

most potent

Atorvastatin

hyperlipidemia

Atorvastatin


Input: However, there are few reports in the literature of ampicillin as a cause of acute interstitial nephritis.

cause

acute interstitial nephritis

ampicillin

ampicillin


Input: Optic neuropathy in ethambutol-treated renal tuberculosis.

treated

Optic neuropathy

ethambutol

ethambutol

renal tuberculosis


Input: This case study describes an atypical case of refractory, sodium warfarin-induced necrotizing fasciitis and myonecrosis.

induced

necrotizing fasciitis and myonecrosis

sodium warfarin

sodium warfarin


Input: OBJECTIVE: To report a case of possible foscarnet-induced severe hypomagnesemia and other electrolyte disorders.

induced

a case

severe hypomagnesemia and other electrolyte disorders

foscarnet

foscarnet


Input: However, the occurrence and management of akathisia induced by fluvoxamine have not been described.

induced

akathisia

fluvoxamine

fluvoxamine


Input: Nephrotic syndrome associated with interferon-beta-1b therapy for multiple sclerosis.

associated with

Nephrotic syndrome

interferon-beta-1b therapy

multiple sclerosis.


Input: OBSERVATIONS: A 48-year-old woman presented with disfiguring facial edema 10 weeks after she began antiviral therapy with peginterferon alfa-2a and ribavirin for chronic hepatitis C infection.

after

A 48-year-old woman

woman

disfiguring facial edema

10 weeks

antiviral therapy with peginterferon alfa-2a and ribavirin

chronic hepatitis C infection

10 weeks

peginterferon alfa-2a

ribavirin

peginterferon alfa-2a

ribavirin


Input: Two of these patients, who also received the anti-emetic prochlorperazine, lost consciousness for 48-72 h and then fully recovered.

lost

Two of these patients

Two

lost consciousness for 48-72 h and then fully recovered

anti-emetic prochlorperazine

prochlorperazine


Input: We present a depressive patient who developed mild parkinsonian signs and camptocormia after the introduction of olanzapine.

developed

depressive patient

mild parkinsonian signs and camptocormia

introduction of olanzapine

olanzapine

depressive


Input: The case report discussed is, to our knowledge, the third of its kind regarding bone fluorosis resulting from use of this nicotinic derivative.

use

bone fluorosis

nicotinic derivative

nicotinic derivative


Input: We report a case of Thrombotic Thrombocytopenic Purpura occurring as an allergic response to trimethoprim-sulfamethoxazole therapy (Bactrim, Septra) in a Jehovah's Witness patient.

to

Jehovah's Witness patient

Thrombotic Thrombocytopenic Purpura

allergic response

trimethoprim-sulfamethoxazole

trimethoprim

sulfamethoxazole

trimethoprim

sulfamethoxazole


Input: A 25-year-old white woman with chronic depression was treated with venlafaxine 150 mg/d and trimipramine 50 mg/d.

treated

A 25-year-old white woman with chronic depression

white

woman

venlafaxine 150 mg/d and trimipramine 50 mg/d

chronic depression

venlafaxine

trimipramine

150 mg/d

50 mg/d

venlafaxine

trimipramine


Input: A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.

developed

A 31-year-old female

female

multiple episodes of grand mal seizures

combination chemotherapy with cisplatin, vinblastine and bleomycin

germ cell ovarian cancer stage Ic

bleomycin

vinblastine

cisplatin

cisplatin

vinblastine

bleomycin


Input: Nephrogenic diabetes insipidus and renal tubular acidosis secondary to foscarnet therapy.

secondary

Nephrogenic diabetes insipidus and renal tubular acidosis

foscarnet

foscarnet


Input: PURPOSE: Topiramate-induced angle-closure glaucoma (TiACG) is believed to be related to its sulfonamide moiety.

induced

angle-closure glaucoma (TiACG)

Topiramate

Topiramate


Input: These toxicities resolved after the cessation of anticonvulsants, and her seizures were managed acutely with scheduled lorazepam.

managed

lorazepam

seizures

lorazepam


Input: This article reports the occurrence of rifampin-associated thrombocytopenia in an indigent patient after a four-month lapse in therapy for pulmonary tuberculosis.

associated

an indigent patient

thrombocytopenia

rifampin

after a four-month lapse in therapy for pulmonary tuberculosis

rifampin

four-month

pulmonary tuberculosis


Input: Drug-induced psychosis resulted from the administration of quinacrine hydrochloride at a dosage of 100 mg twice daily for the treatment of discoid lupus.

induced

psychosis resulted

administration of quinacrine hydrochloride at a dosage of 100 mg twice daily

100 mg

twice daily

discoid lupus

quinacrine hydrochloride


Input: We report a case of a scleroderma-like reaction induced by long-term administration of UFT.

induced

a case

a scleroderma-like reaction

long-term administration of UFT

long-term

UFT


Input: We report four cases of hemodynamically significant pericardial effusion in patients with refractory lymphoma who were receiving gemcitabine, all of whom had a history of mediastinal radiation without subcarinal blocking.

in

had a history of mediastinal radiation without subcarinal blocking

mediastinal radiation without subcarinal blocking

four

hemodynamically significant pericardial effusion

gemcitabine

refractory lymphoma

gemcitabine


Input: Both had impaired lung function and abnormal computed tomographic scans, and their condition improved when nitrofurantoin was withdrawn and corticosteroid treatment commenced.

improved

Both had impaired lung function and abnormal computed tomographic scans

Both

abnormal computed tomographic scans

nitrofurantoin was withdrawn and corticosteroid treatment commenced

corticosteroid

nitrofurantoin

impaired lung function


Input: OBJECTIVE: The purpose of this study was to report the concomitant occurrence of multiple squamous cell carcinomas and diffuse nail hyperpigmentation associated with hydroxyurea treatment, and to describe a successful therapeutic approach using imiquimod 5%.

associated

multiple squamous cell carcinomas and diffuse nail hyperpigmentation

hydroxyurea

hydroxyurea


Input: We present a case report of a patient who developed a prolonged QT while being treated with oral methadone for a chronic pain syndrome.

treated

a patient

prolonged QT

oral methadone

methadone

oral

chronic pain syndrome


Input: In this article, we describe a Japanese patient with severe interstitial pneumonia probably caused by sorafenib treatment for metastatic renal cell carcinoma.

caused

a Japanese patient

Japanese

severe interstitial pneumonia

sorafenib

metastatic renal cell carcinoma

sorafenib


Input: Neurotoxicity occurs most often with intermittent high dose 5-FU as bolus injection or 24- to 48-h infusions.

occurs

Neurotoxicity

intermittent high dose 5-FU as bolus injection or 24- to 48-h infusions

high dose

injection

infusions


Input: Lovastatin also reportedly has caused increases in INR when coadministered with warfarin.

caused

increases in INR

Lovastatin

Lovastatin


Input: Pravastatin does not appear to interact with warfarin but has caused an increased INR when combined with the anticoagulant fluindione.

caused

increased INR

Pravastatin

combined with the anticoagulant fluindione

Pravastatin

anticoagulant fluindione

Pravastatin

anticoagulant fluindione


Input: Bromocriptine-induced schizophrenia.

induced

schizophrenia

Bromocriptine

Bromocriptine


Input: Pulmonary toxicity associated with erlotinib.

associated

Pulmonary toxicity

erlotinib

erlotinib


Input: Multicentric hepatocellular carcinoma following phosphate diethylstilbestrol therapy for prostatic cancer.

following

Multicentric hepatocellular carcinoma

phosphate diethylstilbestrol

phosphate diethylstilbestrol

prostatic cancer


Input: Rapid onset of quetiapine-induced diabetic ketoacidosis in an elderly patient: a case report.

induced

an elderly patient

elderly

diabetic ketoacidosis

quetiapine

quetiapine


Input: A 57-year-old woman developed pulmonary sarcoidosis during therapy with interferon beta for advanced renal cell carcinoma metastatic to mediastinal lymph nodes.

developed

57-year-old woman

woman

pulmonary sarcoidosis

interferon beta for advanced renal cell carcinoma metastatic to mediastinal lymph nodes

advanced renal cell carcinoma metastatic to mediastinal lymph nodes

interferon beta


Input: Mesalamine-induced hypersensitivity pneumonitis.

induced

hypersensitivity pneumonitis

Mesalamine

Mesalamine


Input: A girl with cystic fibrosis and cyclic neutropenia developed an erythematous papular eruption without fever or neutrophilia 7 months after commencing therapy with G-CSF.

developed

A girl with cystic fibrosis and cyclic neutropenia

girl

cystic fibrosis

erythematous papular eruption without fever or neutrophilia

7 months after commencing therapy with G-CSF.

cyclic neutropenia

G-CSF

7 months


Input: Lichen planus and acne provoked by gold.

provoked

Lichen planus and acne

gold

gold


Input: To the best of our knowledge only two previous cases of AML have been linked to treatment of HCL with purine analogs, both with 2-chlorodeoxyadenosine.

linked

AML

purine analogs, both with 2-chlorodeoxyadenosine

HCL


Input: There are no previous reports in the literature about the emergence of CML during treatment with hydroxyurea.

during

CML

treatment with hydroxyurea

hydroxyurea


Input: Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.

associated

significant hypotension

Intravenous valproate

status epilepticus

Intravenous

valproate


Input: Torsade de pointes associated with moxifloxacin: a rare but potentially fatal adverse event.

associated

Torsade de pointes

moxifloxacin

moxifloxacin


Input: We report serious adverse effects due to interaction between orally administered voriconazole and everolimus in a renal transplant recipient.

due to

a renal transplant recipient

renal transplant

serious adverse effects

interaction between orally administered voriconazole and everolimus

voriconazole

everolimus

orally

voriconazole

everolimus


Input: Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside.

caused

Horner's syndrome and demyelinating peripheral neuropathy

high-dose cytosine arabinoside

high-dose

cytosine arabinoside


Input: Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: a review of the literature and implications for practice.

after

radiation myelopathy

high-dose busulfan

melphalan

high-dose

busulfan

melphalan

Ewing's sarcoma:

busulfan

melphalan


Input: This is the first description, to our knowledge, of ductopenia apparently caused by clindamycin.

caused

ductopenia

clindamycin

clindamycin


Input: Mefloquine-associated hypoglycaemia in a cachectic AIDS patient.

associated

cachectic AIDS patient

cachectic AIDS

hypoglycaemia

Mefloquine

Mefloquine


Input: Patients who commonly require linezolid as an antimicrobial are those with complex infections where other antibiotic treatment has failed.

require

Patients

complex infections

linezolid as an antimicrobial

linezolid

complex infections


Input: In three of these patients the infection was clinically unsuspected; in the fourth, cutaneous herpes zoster developed after administration of 300 mg of cytarabine daily for the preceding five days.

developed

three of these patients

three

cutaneous herpes zoster

300 mg of cytarabine daily for the preceding five days

300 mg

cytarabine

daily

preceding five days


Input: Patients receiving linezolid for more than 28 days should be monitored for signs of peripheral and optic neuropathy.

monitored

Patients

peripheral and optic neuropathy

linezolid for more than 28 days

linezolid

28 days


Input: Atrioventricular block complicating amiodarone-induced hypothyroidism in a patient with pre-excitation and rate-dependent bilateral bundle branch block.

induced

a patient with pre-excitation and rate-dependent bilateral bundle branch block

pre-excitation

rate-dependent bilateral bundle branch block

Atrioventricular block

hypothyroidism

amiodarone

amiodarone


Input: Lithium is known to cause acute renal failure and tubulo-interstitial disease, but the recently described association with proteinuria or nephrotic syndrome is little recognized.

association

acute renal failure and tubulo-interstitial disease

proteinuria or nephrotic syndrome

Lithium

Lithium


Input: A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation.

after

40-year-old man with advanced HIV infection and Mycobacterium avium complex infection

man

rapid cognitive decline

commencement of ethambutol

ethambutol

ethambutol

Mycobacterium avium complex infection

HIV infection


Input: Ciprofloxacin-induced hemorrhagic vasculitis is a rare side effect.

induced

hemorrhagic vasculitis

Ciprofloxacin

Ciprofloxacin


Input: Given that significant thyroid disorders may be only mildly symptomatic and thus may escape clinical detection, we suggest that thyroid function should be tested in any patient with otherwise unexplained changes in warfarin dose requirements, particularly if concomitantly treated with amiodarone.

changes

significant thyroid disorders

warfarin

with amiodarone

warfarin

amiodarone

amiodarone

warfarin


Input: Myotonia associated with sarcoidosis: marked exacerbation with pravastatin.

associated

sarcoidosis

sarcoidosis

exacerbation

Myotonia

pravastatin

pravastatin


Input: This observation questions the suitability of aspirin as prophylaxis for vascular disease in patients with meningiomas.

prophylaxis

patients with meningiomas

meningiomas

aspirin

aspirin

vascular disease


Input: Delayed neurotoxicity of intraventricular interleukin-2: a case report.

of

a case report

Delayed neurotoxicity

intraventricular interleukin-2

intraventricular


Input: We stress the potential of benzarone to cause hepatotoxicity, which usually resembles severe chronic active hepatitis.

cause

hepatotoxicity

severe chronic active hepatitis

benzarone

benzarone


Input: We describe a patient with Wilson's disease who presented with neurologic disease, was treated with D-penicillamine, and suffered sudden neurologic deterioration coincident with therapy.

suffered

a patient with Wilson's disease who presented with neurologic disease

neurologic disease

sudden neurologic deterioration

D-penicillamine

Wilson's disease

D-penicillamine


Input: We report the case of a 21-year-old female patient with dapsone hypersensitivity syndrome.

with

a 21-year-old female patient

female

hypersensitivity syndrome

dapsone

dapsone


Input: The adverse events related to ribavirin and drug-drug interactions during therapy for hepatitis C are discussed.

related

adverse events

ribavirin

ribavirin

hepatitis C


Input: Insulin-dependent diabetes mellitus developed in a young woman 8 weeks after the initiation of danazol for treatment of pelvic endometriosis.

after

a young woman

young

woman

Insulin-dependent diabetes mellitus

8 weeks after the initiation of danazol

pelvic endometriosis

8 weeks

danazol


Input: Four cases of fat embolism are described in infants receiving prolonged intravenous infusion of fat (Intralipid 20%).

receiving

Four cases

infants

infants

Four

fat embolism

prolonged intravenous infusion of fat (Intralipid 20%)

intravenous infusion

Intralipid


Input: Oral adverse effects due to the use of Nevirapine.

due

adverse effects

Nevirapine

Oral

Nevirapine


Input: PURPOSE: A case of probable enoxaparin-induced hepatotoxicity is described.

induced

hepatotoxicity

enoxaparin

enoxaparin


Input: Tizanidine was used again after her BP had stabilized, but did not produce similar problems.

produce

problems

Tizanidine

Tizanidine


Input: It is suggested therefore that methotrexate be added to the list of agents capable of inducing diffuse interstitial pulmonary fibrosis.

inducing

diffuse interstitial pulmonary fibrosis

methotrexate

methotrexate


Input: The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate.

developed

delayed encephalopathy

intrathecal methotrexate

9 and 22 months

methotrexate

intrathecal


Input: Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy.

after

Severe systemic hypersensitivity reaction

ibuprofen

prolonged therapy

ibuprofen

prolonged therapy


Input: In patients with chronic heart failure, spironolactone added to conventional treatment may lead to serious and, occasionally, fatal hyperkalaemia.

lead

patients with chronic heart failure

chronic heart failure

serious and, occasionally, fatal hyperkalaemia

spironolactone

spironolactone


Input: We report a case of acute hyperphosphatemia secondary to rectal administration of sodium phosphate and sodium biphosphate (Fleet enema).

secondary

acute hyperphosphatemia

rectal administration of sodium phosphate and sodium biphosphate (Fleet enema)

rectal

sodium phosphate

sodium biphosphate

sodium phosphate

sodium biphosphate


Input: Visual changes secondary to initiation of amiodarone: a case report and review involving ocular management in cardiac polypharmacy.

secondary

a case

Visual changes

amiodarone

amiodarone


Input: This is the first case, to our knowledge, of onset of prolonged infliximab-induced lupus.

induced

lupus

infliximab

prolonged

infliximab


Input: A patient with developmental disabilities who had no history of movement disorders developed EPS following initiation of aripiprazole.

following

A patient with developmental disabilities who had no history of movement disorders

developmental disabilities

EPS

initiation of aripiprazole

aripiprazole


Input: Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug.

associated

Case

life-threatening hypoglycaemia

sulfadoxine-pyrimethamine

sulfadoxine-pyrimethamine


Input: Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate.

to

treatment with sodium bicarbonate

Diphenhydramine-induced wide complex dysrhythmia

Diphenhydramine

sodium bicarbonate


Input: Prenatal cytomegalovirus (CMV) infection associated with severe brain damage was detected in an infant whose mother had been treated with prednisolone and azathioprine for systemic lupus erythematosus (SLE).

treated

an infant whose mother had been treated with prednisolone and azathioprine for systemic lupus erythematosus (SLE)

infant

Prenatal cytomegalovirus (CMV) infection associated with severe brain damage

prednisolone and azathioprine

prednisolone

azathioprine

prednisolone

azathioprine


Input: Methotrexate may rarely provoke serositis, even with low doses and after just a few weeks of therapy.

provoke

serositis

Methotrexate

Methotrexate


Input: Prescription analyses by pharmacists and literature research have permitted us to suggest that a drug-drug interaction between methotrexate and proton pump inhibitors (PPI) was responsible for this renal failure.

responsible

renal failure

methotrexate and proton pump inhibitors (PPI)

methotrexate

proton pump inhibitors (PPI)

methotrexate

proton pump inhibitors (PPI)


Input: Asthma and urticaria during disodium cromoglycate treatment.

during

Asthma and urticaria

disodium cromoglycate treatment

disodium cromoglycate


Input: We suggest that the previous classification of nitrofurantoin induced lung injury into "acute" and "chronic" injury is an oversimplification in view of the wide variety of pathological entities that have subsequently emerged.

induced

lung injury

nitrofurantoin

nitrofurantoin


Input: Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate.

taking

a woman with rheumatoid arthritis

woman

Hepatitis with bridging fibrosis and reversible hepatic insufficiency

methotrexate

rheumatoid arthritis

methotrexate


Input: Primary CNS lymphoma regressed on withdrawal of MM.

regressed

Primary CNS lymphoma

withdrawal of MM

MM


Input: Pemphigus foliaceus induced by rifampicin.

induced

Pemphigus foliaceus

rifampicin

rifampicin


Input: L-T4 stimulated lymphocyte transformation in this patient.

stimulated

this patient

lymphocyte transformation


Input: A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.

after

A 53-year-old man

man

lower leg edema

4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day

4 weeks

rosiglitazone

4 mg

twice/day


Input: A mentally retarded 23-year-old woman with myoclonic astatic epilepsy developed an abnormal posture of extreme forward flexion, called camptocormia, during valproate monotherapy.

during

A mentally retarded 23-year-old woman with myoclonic astatic epilepsy

mentally retarded

abnormal posture of extreme forward flexion, called camptocormia,

valproate

valproate

myoclonic astatic epilepsy


Input: After 5 days of treatment with IL-2, the patient developed a hemorrhagic lesion that progressed to toxic epidermal necrolysis, as well as grade 4 pancytopenia.

developed

patient

a hemorrhagic lesion that progressed to toxic epidermal necrolysis, as well as grade 4 pancytopenia

5 days of treatment with IL-2

After 5 days


Input: Acute pancreatitis after long-term 5-aminosalicylic acid therapy.

after

Acute pancreatitis

long-term 5-aminosalicylic acid therapy

5-aminosalicylic acid

long-term