Input: Abiraterone acetate, an androgen biosynthesis inhibitor, prolongs survival in men with metastatic castration-resistant prostate cancer (mCRPC) in the pre- and post-chemotherapy setting as demonstrated by the pivotal phase III studies COU-AA-301 and COU-AA-302.

prolongs survival

men with metastatic castration-resistant prostate cancer (mCRPC)

men

Abiraterone acetate, an androgen biosynthesis inhibitor

Abiraterone acetate

metastatic castration-resistant prostate cancer


Input: Reduction of methylprednisolone dosage rather than insulin therapy resulted in better control of glycemia.

resulted

Reduction of methylprednisolone dosage rather than insulin therapy

methylprednisolone

Reduction

glycemia


Input: Here, we report a case of RFP-induced hypothyroidism without underlying thyroid disease.

induced

hypothyroidism without underlying thyroid disease

RFP

RFP


Input: Here we report ramipril-induced cutaneous vasculitis in a patient who required steroid therapy to control it.

induced

a patient

cutaneous vasculitis

ramipril

ramipril


Input: A 78-year-old man with a transvenous cardioverter defibrillator system developed frequent shocks during oral procainamide therapy.

developed

A 78-year-old man with a transvenous cardioverter defibrillator system

man

frequent shocks

during oral procainamide therapy

a transvenous cardioverter defibrillator system

oral

procainamide


Input: A 53 year old Greenlandic male was admitted twice over a period of 4 years with a new complete right bundle branch block after ingestion of 10 g and 4 g of carbamazepine respectively.

after

A 53 year old Greenlandic male

53 year old

Greenlandic

male

was admitted twice over a period of 4 years with a new complete right bundle branch block

ingestion of 10 g and 4 g of carbamazepine

ingestion

10 g and 4 g

carbamazepine


Input: In contrast, other common agents for the most part trigger cutaneous inflammation.

trigger

cutaneous inflammation

other common agents for the most part

other common agents


Input: In both patients the rippling phenomena worsened with pyridostigmine treatment but markedly improved after immunosuppression with azathioprine.

worsened

both patients

both

rippling phenomena

pyridostigmine

pyridostigmine


Input: We present findings from three patients who experienced a psoriasiform eruption apparently due to the antiepileptic agents sodium valproate and carbamazepine.

due to

three patients

three

psoriasiform eruption

antiepileptic agents sodium valproate and carbamazepine

sodium valproate

carbamazepine

sodium valproate

carbamazepine


Input: We report here such a case with bilateral Mooren's ulcer that failed to respond to local therapy with topical corticosteroids, silver nitrate, and conjunctival resection, as well as systemic immunosuppression with corticosteroids, cyclophosphamide, and azathioprine.

respond

a case with bilateral Mooren's ulcer

local therapy with topical corticosteroids, silver nitrate, and conjunctival resection, as well as systemic immunosuppression with corticosteroids, cyclophosphamide, and azathioprine

corticosteroids

silver nitrate

corticosteroids

cyclophosphamide

azathioprine

bilateral Mooren's ulcer

topical

corticosteroids

silver nitrate

corticosteroids

cyclophosphamide

azathioprine


Input: Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report.

Successful treatment

carbimazole

a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration

carbimazole


Input: Jaundice induced by streptokinase.

induced

Jaundice

streptokinase

streptokinase


Input: When thrombosis develops during heparin treatment, it is important to suspect HITTs and to assay for the associated antibodies, regardless of the actual platelet count.

develops

thrombosis

HITTs

heparin

heparin


Input: The results in this case suggest that cyclosporin is an effective agent in patients with severe sight threatening Mooren's ulcer.

effective

patients with severe sight threatening Mooren's ulcer

is an effective agent

cyclosporin

Mooren's ulcer

cyclosporin


Input: CONCLUSIONS: Amphotericin B overdose can be fatal in children and infants.

be

children and infants

children

infants

Amphotericin B overdose

Amphotericin B

overdose


Input: Five and one-half years after the diagnosis of myeloma, while in remission on cyclophosphamide therapy, the patient experienced severe abdominal right lower quadrant pain due to a large cecal lymphoma.

experienced

diagnosis of myeloma

patient

severe abdominal right lower quadrant pain

large cecal lymphoma

cyclophosphamide therapy

cyclophosphamide

myeloma


Input: Leukaemoid monocytosis in M4 AML following chemotherapy and G-CSF.

following

Leukaemoid monocytosis in M4 AML

chemotherapy and G-CSF

G-CSF


Input: Vitiligo associated with alpha-interferon in a patient with chronic active hepatitis C.

associated

a patient with chronic active hepatitis C.

Vitiligo

alpha-interferon

alpha-interferon

chronic active hepatitis C.


Input: We report a case of fulminant neuroleptic malignant syndrome in a man aged 70 developing within 12 hours of starting six-hourly intravenous metoclopramide.

developing

a man aged 70

man

aged 70

fulminant neuroleptic malignant syndrome

six-hourly intravenous metoclopramide

within 12 hours

intravenous

metoclopramide

six-hourly


Input: CASE PRESENTATION: We report a patient with CF who developed recurrent eosinophilia and severe persistent bronchospasm following repeated administration of preservative-free tobramycin by inhalation, beginning at 16 months of age.

developed

a patient with CF

beginning at 16 months of age

16 months

recurrent eosinophilia and severe persistent bronchospasm

repeated administration of preservative-free tobramycin by inhalation

CF

tobramycin

inhalation


Input: Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.

after

two cases

two

Ballistic movements due to ischemic infarcts

intravenous heroin overdose

heroin


Input: A case of barbiturate-induced submassive hepatic necrosis is presented and the literature is reviewed.

induced

A case

submassive hepatic necrosis

barbiturate

barbiturate


Input: With combined use, clinicians should be aware, when phenytoin is added, of the potential for reexacerbation of pulmonary symptomatology due to lowered serum theophylline concentrations.

due

reexacerbation of pulmonary symptomatology

phenytoin is added

theophylline

phenytoin

theophylline

phenytoin

theophylline


Input: Fluoxetine-induced akathisia: clinical and theoretical implications.

induced

akathisia

Fluoxetine

Fluoxetine


Input: Lansoprazole-associated collagenous colitis: a case report.

associated

collagenous colitis

Lansoprazole

Lansoprazole


Input: We discuss a variety of bronchopulmonary complications of IBD and their association with sulfasalazine.

association

a variety of bronchopulmonary complications of IBD

sulfasalazine

sulfasalazine


Input: OBJECTIVE: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient.

after

an Asian patient

Asian

the late development of immune-mediated diabetes mellitus

alfa-interferon

alfa-interferon

hepatitis C


Input: The tirapazamine-plus-cisplatin regimen was associated with mild to moderate adverse events, including acute, reversible hearing loss, reversible, intermittent muscle cramping, diarrhea, skin rash, nausea, and vomiting.

associated

mild to moderate adverse events, including acute, reversible hearing loss, reversible, intermittent muscle cramping, diarrhea, skin rash, nausea, and vomiting

tirapazamine-plus-cisplatin regimen

tirapazamine

cisplatin

tirapazamine

cisplatin


Input: To the best of our knowledge, corneoscleral melting in the first postoperative week after a single intraoperative application of mitomycin C has not been reported.

after

corneoscleral melting

a single intraoperative application of mitomycin C

a single intraoperative application

mitomycin C


Input: Thrombo-embolic complication after streptokinase therapy of pulmonary emboli.

after

Thrombo-embolic complication

streptokinase

streptokinase

pulmonary emboli.


Input: Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report.

induced

case

neurotoxicity

Amebic abscess of the spleen complicated

metronidazole

metronidazole


Input: Subfulminant hepatitis B after infliximab in Crohn's disease: need for HBV-screening?

after

Subfulminant hepatitis B

infliximab

infliximab

Crohn's disease


Input: Disseminated salmonellosis in a patient treated with temozolomide.

in

a patient

Disseminated salmonellosis

temozolomide

temozolomide


Input: The aim of our paper was to describe hepatotoxicity of sirolimus (SRL) in a kidney graft recipient.

in

a kidney graft recipient

kidney graft

hepatotoxicity

sirolimus (SRL)

sirolimus


Input: Idiosyncratic pulmonary reactions to nitrofurantoin are not unusual, often presenting as eosinophilic pneumonia.

to

Idiosyncratic pulmonary reactions

eosinophilic pneumonia

nitrofurantoin

nitrofurantoin


Input: The NZ Pharmacovigilance Centre has received 7 additional reports of severe infections in patients with RA taking leflunomide.

taking

patients with RA

severe infections

leflunomide

RA

leflunomide


Input: In addition, loading with one low oral dose of serine produced psychotic symptoms 5 h later which lasted 3-6 h.

loading

psychotic symptoms

one low oral dose of serine

5 h later

low

dose

oral

serine

5 h


Input: Localized purpura associated with lamotrigine.

associated

Localized purpura

lamotrigine

lamotrigine


Input: Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.

in

a patient

Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension

trimethoprim-sulfamethoxazole

trimethoprim

sulfamethoxazole

trimethoprim

sulfamethoxazole


Input: Torsemide appears to also be a part of a long list of agents that can cause pancreatitis.

cause

pancreatitis

Torsemide

Torsemide


Input: Sulfasalazine has been associated with bronchopulmonary complications of inflammatory bowel disease (IBD) in adults.

associated

adults

adults

bronchopulmonary complications of inflammatory bowel disease (IBD)

Sulfasalazine

Sulfasalazine


Input: Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia.

induced

a patient with essential thrombocythemia

interstitial pneumonitis

Hydroxyurea

Hydroxyurea

essential thrombocythemia


Input: The reported case represents an unusual association between medication with the proton pump inhibitor lansoprazole and the development of collagenous colitis suggesting the importance of evaluation of drug use in patients with microscopic colitis.

association

patients with microscopic colitis

microscopic colitis

collagenous colitis

proton pump inhibitor lansoprazole

lansoprazole


Input: The temporal sequence of the respiratory insufficiency and the histopathology, when compared to the previous examples in the literature, suggest that cyclophosphamide was aetiologically responsible for the lung disease.

responsible

lung disease

cyclophosphamide

cyclophosphamide


Input: A 57-year-old man developed chronic, watery diarrhea four weeks after Helicobacter pylori eradication therapy including lansoprazole followed by lansoprazole monotherapy for gastroesophageal reflux disease.

developed

57-year-old man

man

chronic, watery diarrhea

four weeks after Helicobacter pylori eradication therapy including lansoprazole followed by lansoprazole monotherapy for gastroesophageal reflux disease

gastroesophageal reflux disease

lansoprazole

lansoprazole

four weeks

lansoprazole

lansoprazole


Input: We believe that this represents an unusual case of moderate-dose MTX-induced neurotoxicity in a patient with gastric cancer, which has not previously been reported.

induced

patient with gastric cancer

neurotoxicity

moderate-dose MTX

gastric cancer

MTX

moderate-dose


Input: The patient expired after seven cycles of treatment had been completed because of pulmonary fibrosis and the drug toxicity of bleomycin.

after

The patient

expired

seven cycles of treatment

drug toxicity of bleomycin

seven cycles

bleomycin


Input: A statistical association between the incidence of DVT and combination chemotherapy including doxorubicin (P =.02) was observed; this association was confirmed on multivariate analysis.

association

DVT

combination chemotherapy including doxorubicin (P =.02)

chemotherapy

doxorubicin

chemotherapy

doxorubicin


Input: Bleomycin pneumonitis potentiated by oxygen administration.

by

Bleomycin pneumonitis

oxygen administration

oxygen


Input: After five and six weeks of continuous oral administration of methylprednisolone, the boys developed steroid diabetes.

developed

boys

boys

steroid diabetes

After five and six weeks of continuous oral administration of methylprednisolone

After five and six weeks

oral

methylprednisolone


Input: CONCLUSION: This report describes a case of a probable interaction between topical econazole lotion 1% and acenocoumarol that resulted in overanticoagulation and a life-threatening laryngeal hematoma in this elderly patient.

resulted

elderly patient

elderly

overanticoagulation and a life-threatening laryngeal hematoma

a probable interaction between topical econazole lotion 1% and acenocoumarol

econazole

acenocoumarol

topical

lotion

econazole

acenocoumarol


Input: Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy.

related

Pulmonary lymphohistiocytic reactions

etanercept

etanercept


Input: Disseminated tuberculous lesions post intravesical BCG therapy are rare but need to be identified and treated quickly.

post

Disseminated tuberculous lesions

BCG

BCG


Input: Rhabdomyolysis can occur with all statins when used alone and particularly when combined with other drugs that are themselves myotoxic or that elevate the concentration of the statin.

occur

Rhabdomyolysis

statins

other drugs that are themselves myotoxic or that elevate the concentration of the statin

statins


Input: Amiodarone-induced dysthyroidism.

induced

dysthyroidism

Amiodarone

Amiodarone


Input: Two patients with imminent gangrene of the extremities caused by ergot-induced arteriospasm underwent mechanical dilatation of the arteries when conventional measures such as anticoagulation, vasodilation, and sympathetic blockade produced no improvement.

induced

arteriospasm

ergot

ergot


Input: Acute coronary syndromes can be associated with the infusion of rituximab.

associated

Acute coronary syndromes

infusion of rituximab

rituximab

infusion


Input: Approximately 15 min after the first administration of nebulised morphine the patient became markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70/40 mmHg), and responded only partially to command.

became

patient

markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70/40 mmHg), and responded only partially to command

nebulised morphine

morphine

nebulised

15 min


Input: Akathisia appeared to be a common side effect of fluoxetine and generally responded well to treatment with the beta-adrenergic antagonist propranolol, dose reduction, or both.

responded

beta-adrenergic antagonist propranolol

Akathisia

fluoxetine


Input: An unusual cause of burn injury: unsupervised use of drugs that contain psoralens.

cause

burn injury

use of drugs that contain psoralens.

psoralens


Input: The patient suffered a life-threatening anaphylactoid reaction to amifostine.

suffered

patient

life-threatening anaphylactoid reaction

amifostine

amifostine


Input: We report three cases of severe hypocalcaemia associated with i.v. bisphosphonate treatment in patients with multiple myeloma.

associated

patients with multiple myeloma

three

severe hypocalcaemia

i.v. bisphosphonate treatment

multiple myeloma

bisphosphonate

i.v.


Input: We report a case of exfoliative dermatitis clearly linked to intravenous and intraperitoneal administration of tobramycin.

linked

a case

exfoliative dermatitis

intravenous and intraperitoneal administration of tobramycin

intravenous

intraperitoneal

tobramycin


Input: Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.

induced

Glomerulonephritis

lupus erythematosus

procainamide

procainamide


Input: Patients treated with captopril who develop "atypical cholangitis" should be suspected of having captopril-associated liver damage.

associated

Patients

atypical cholangitis

liver damage

captopril

captopril

captopril


Input: We report a case of codeine intoxication in the neonate, in which the drug was prescribed for cough control during an emergency department visit.

prescribed

in the neonate

for cough control during an emergency department visit

neonate

intoxication

codeine

codeine

cough


Input: Discontinuation of simvastatin and cyclosporine resulted in resolution of rhabdomyolysis and normalization of renal function.

resulted

normalization of renal function

Discontinuation of simvastatin and cyclosporine

rhabdomyolysis

simvastatin

cyclosporine


Input: Phenylpropanolamine (PPA) recently has been publicly implicated as a cause of stroke and other neurologic events.

cause

stroke and other neurologic events

Phenylpropanolamine (PPA)

Phenylpropanolamine


Input: Critically elevated INR in a patient on warfarin after increase in extended-release niacin dose.

after

a patient

elevated INR

warfarin

increase in extended-release niacin dose

warfarin

niacin

increase in

dose


Input: He developed severe hyperactivity and agitation on taking methylphenidate after the discontinuation of risperidone treatment.

developed

He

He

hyperactivity and agitation

methylphenidate after the discontinuation of risperidone

methylphenidate

risperidone


Input: We suggest that objective evaluation of retinal function with electrophysiological methods should be performed in patients with visual disturbance during treatment with rifabutin.

during

visual disturbance

rifabutin

rifabutin


Input: A clinically atypical, neuropathologically verified case of Creutzfeldt-Jakob disease is described in a 32-year-old New Zealand woman with idiopathic hypopituitarism who had been treated in late adolescence (1970 to 1973) with human growth hormone processed from pooled cadaveric pituitary glands.

described

a 32-year-old New Zealand woman with idiopathic hypopituitarism

New Zealand

woman

Creutzfeldt-Jakob disease

human growth hormone

idiopathic hypopituitarism

human growth hormone


Input: Quinine remains a reliable treatment for falciparum malaria in most parts of the world.

treatment

Quinine

falciparum malaria

Quinine


Input: Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases.

after

corneal toxicity

topical fluoroquinolone therapy

fluoroquinolone


Input: She developed a generalized rash and itching, sore throat, and dizziness approximately 4 hours after the first dose of capecitabine.

developed

a generalized rash and itching, sore throat, and dizziness

approximately 4 hours after the first dose of capecitabine

4 hours

capecitabine


Input: Seizures associated with fluoxetine therapy are uncommon.

associated

Seizures

fluoxetine therapy

fluoxetine


Input: A 14-year-old girl with newly diagnosed SLE developed a pruritic bullous eruption while on prednisone.

developed

A 14-year-old girl with newly diagnosed SLE

girl

a pruritic bullous eruption

prednisone

prednisone

SLE


Input: Sodium valproate and carbamazepine, antiepileptic drugs that are associated with a relatively low rate of adverse cutaneous reactions, should be added to the growing list of drugs that produce psoriasiform eruptions.

associated with

adverse cutaneous reactions

Sodium valproate and carbamazepine

carbamazepine

Sodium valproate


Input: Tirapazamine plus cisplatin versus cisplatin in advanced non-small-cell lung cancer: A report of the international CATAPULT I study group.

in

Tirapazamine plus cisplatin

advanced non-small-cell lung cancer

cisplatin

Tirapazamine

cisplatin

Tirapazamine


Input: Exfoliative dermatitis secondary to tobramycin sulfate.

secondary to

Exfoliative dermatitis

tobramycin sulfate.

tobramycin sulfate


Input: Kaposi's sarcoma in a patient treated with imatinib mesylate for chronic myeloid leukemia.

treated

a patient

Kaposi's sarcoma

imatinib mesylate

chronic myeloid leukemia

imatinib mesylate


Input: A young patient experienced marked sinus tachycardia while smoking marijuana and receiving therapeutic doses of nortriptyline.

experienced

young patient

young

sinus tachycardia

nortriptyline

nortriptyline


Input: Hypogammaglobulinemia associated with gold therapy: evidence for a partial maturation blockade of B cells.

associated

Hypogammaglobulinemia

a partial maturation blockade of B cells

gold therapy

gold


Input: Experience with five patients in whom impaired renal function developed early during amphotericin B therapy is reported.

developed

five patients

five

impaired renal function

amphotericin B therapy

amphotericin B


Input: This report details the pulmonary pathologic findings in four patients with rheumatoid arthritis, who developed new onset of pulmonary signs and symptoms with alveolar infiltrates temporally related to the institution of etanercept therapy.

related to

four patients with rheumatoid arthritis

four

developed new onset of pulmonary signs and symptoms with alveolar infiltrates

institution of etanercept therapy

etanercept

rheumatoid arthritis


Input: CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration.

develop

patients

recurrent eosinophilia and deterioration of pulmonary function

use of tobramycin by inhalation or by intravenous administration

tobramycin

inhalation

intravenous administration.


Input: NCSE, an epileptic disorder in which typical convulsive activity is absent, has previously been reported in only 4 patients receiving ifosfamide.

receiving

4 patients

NCSE

ifosfamide

ifosfamide


Input: We describe a case of life-threatening hyponatremia associated with sibutramine use in an obese woman.

associated

obese woman

hyponatremia

sibutramine

sibutramine

obese


Input: Polymyoclonus seizure resulting from accidental injection of tranexamic acid in spinal anesthesia.

resulting

Polymyoclonus seizure

accidental injection of tranexamic acid in spinal anesthesia

tranexamic acid

injection


Input: Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) have been associated with myopathy and rhabdomyolysis.

associated

myopathy and rhabdomyolysis

Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins)

Hydroxymethylglutaryl coenzyme A reductase inhibitors


Input: Propranolol-induced hypertension in treatment of cocaine intoxication.

induced

hypertension

Propranolol

Propranolol


Input: This is the second report of lactic acidosis in a patient on stavudine and lamivudine.

on

a patient

lactic acidosis

stavudine and lamivudine

stavudine

lamivudine

lamivudine

stavudine


Input: We report on a patient with renal artery stenosis who had only 1 kidney and in whom acute renal impairment developed with transient anuria after the administration of captopril.

after

a patient with renal artery stenosis who had only 1 kidney

renal artery stenosis who had only 1 kidney

acute renal impairment developed with transient anuria

the administration of captopril

captopril


Input: However, in the mid-to-late 1980s, a series of letters to the editor and case reports announced an association between tamoxifen therapy in women with breast cancer and the development of endometrial carcinoma.

development

women with breast cancer

women

endometrial carcinoma

tamoxifen

tamoxifen

breast cancer


Input: Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis.

induced

rhabdomyolysis

cyclosporine treatment

Simvastatin

Simvastatin

cyclosporine

uveitis

cyclosporine

Simvastatin


Input: Based on our previous demonstration that quinine could be used clinically to reverse P-glycoprotein-mediated resistance, we designed a multicenter, randomized trial aiming to determine whether quinine would improve the survival of adult patients (15-60 years old) with de novo acute myelogenous leukemia (AML).

improve

adult patients (15-60 years old)

adult

15-60 years old

reverse P-glycoprotein-mediated resistance

quinine

quinine

de novo acute myelogenous leukemia (AML)


Input: Vincristine induced cranial polyneuropathy.

induced

cranial polyneuropathy

Vincristine

Vincristine


Input: Here we describe another case of VOD occurring after LT, but in which the causative role was played by azathioprine.

occurring

VOD

azathioprine

azathioprine


Input: A retrospective review of TTP patients with quinine-associated thrombotic microangiopathy (TMA) for whom ADAMTS13 was measured before plasma exchange was performed.

associated

TTP patients

TTP

thrombotic microangiopathy (TMA)

quinine

quinine


Input: Rituximab-CHOP induced interstitial pneumonitis in patients with disseminated extranodal marginal zone B cell lymphoma.

induced

patients with disseminated extranodal marginal zone B cell lymphoma

interstitial pneumonitis

Rituximab-CHOP

disseminated extranodal marginal zone B cell lymphoma

Rituximab-CHOP


Input: Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia.

cause

gingival hyperplasia

Nitrendipine is an experimental calcium channel blocking agent

Nitrendipine


Input: The present study describes a patient who had unusual weight fluctuation under corticosteroid and psychotropic treatment such as mianserin and aripiprazole.

had

patient

unusual weight fluctuation

corticosteroid and psychotropic treatment such as mianserin and aripiprazole

mianserin

aripiprazole

mianserin

aripiprazole


Input: Clozapine-induced akathisia in children with schizophrenia.

induced

children with schizophrenia

children

akathisia

Clozapine

Clozapine

schizophrenia


Input: Patients with previously untreated NSCLC were randomized to receive either tirapazamine (390 mg/m(2) infused over 2 hours) followed 1 hour later by cisplatin (75 mg/m(2) over 1 hour) or 75 mg/m(2) of cisplatin alone, every 3 weeks for a maximum of eight cycles.

receive

Patients with previously untreated NSCLC

either tirapazamine (390 mg/m(2) infused over 2 hours) followed 1 hour later by cisplatin (75 mg/m(2) over 1 hour) or 75 mg/m(2) of cisplatin alone, every 3 weeks for a maximum of eight cycles

tirapazamine

cisplatin

cisplatin

390 mg/m(2)

75 mg/m(2)

75 mg/m(2)

infused

over 2 hours

over 1 hour

every 3 weeks for a maximum of eight cycles

NSCLC

tirapazamine

cisplatin


Input: Drug interactions between macrolide antibiotics such as erythomycin and pharmacologic agents that prolong the QT interval have been known to cause TdP. However, clarithromycin is thought to be less frequently associated with drug induced TdP, because it inactivates hepatic cytochrome P-450 to a lesser extent than erythromycin.

cause

TdP.

Drug interactions between macrolide antibiotics such as erythomycin and pharmacologic agents that prolong the QT interval

erythomycin

pharmacologic agents

macrolide antibiotics

erythomycin

pharmacologic agents


Input: In a randomised, investigator-blinded, multicentre phase III efficacy trial, 899 infants and children with acute uncomplicated Plasmodium falciparum malaria received six doses of AL according to body weight over 3 days either as crushed tablets (Coartem) or as dispersible tablets.

received

899 infants and children with acute uncomplicated Plasmodium falciparum malaria

infants and children

six doses of AL according to body weight over 3 days either as crushed tablets (Coartem) or as dispersible tablets

AL

3 days

six doses

Plasmodium falciparum malaria

crushed tablets

dispersible tablets


Input: A patient presented with dilated cardiomyopathy after many years of overusing an adrenaline inhaler.

after

A patient

dilated cardiomyopathy

many years of overusing an adrenaline inhaler

overusing

adrenaline

inhaler


Input: Occurrence of withdrawal dyskinesia indicates that the neuroleptic effects of amoxapine may be clinically significant.

Occurrence

withdrawal dyskinesia

amoxapine

amoxapine


Input: Hair loss associated with paroxetine treatment: a case report.

associated

a case

Hair loss

paroxetine

paroxetine


Input: RESULTS: In a 22-year-old Thai woman with Graves' disease, tinnitus, hearing impairment in the left ear (with progression to the right ear), and vertigo developed after 3 years of therapy with PTU.

developed

a 22-year-old Thai woman with Graves' disease

Thai

woman

tinnitus, hearing impairment in the left ear (with progression to the right ear), and vertigo

after 3 years of therapy with PTU

Graves' disease

PTU

after 3 years


Input: Additive pulmonary toxicity with melphalan and busulfan therapy.

with

Additive pulmonary toxicity

melphalan and busulfan therapy

melphalan

busulfan

melphalan

busulfan


Input: We report the case of a 20-year-old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis, identified 1 month after a single dose of ivermectin.

developed

20-year-old woman originally from Cameroon who was infected by the L. loa parasite

woman

Cameroon

severe hepatitis

1 month after a single dose of ivermectin

infected by the L. loa parasite

1 month

single dose

ivermectin


Input: To the best of our knowledge, this is the first case of lithium-associated CDI and NDI presenting concurrently.

associated

CDI and NDI

lithium

lithium


Input: In this healthy population, the relative risk of developing endometrial carcinoma in the tamoxifen arm was 2.54, although when stratified by age, in women over 50, the risk grew to 4.01.

developing

healthy population

endometrial carcinoma

tamoxifen

tamoxifen


Input: Paradoxical ventricular tachycardia and fibrillation after intravenous bretylium therapy.

after

Paradoxical ventricular tachycardia and fibrillation

intravenous bretylium

intravenous

bretylium


Input: OBJECTIVE: To describe a case of thrombocytopenia associated with the administration of lansoprazole.

associated

a case

thrombocytopenia

lansoprazole

lansoprazole


Input: A patient developed optic neuropathy while being treated with isoniazid and ethambutol.

developed

A patient

optic neuropathy

isoniazid and ethambutol

isoniazid

ethambutol

isoniazid

ethambutol


Input: This case describes a 52-year-old white woman who developed a spontaneous nasal septal perforation after given the antiangiogenic drug, bevacizumab, for metastatic ovarian cancer treatment.

developed

a 52-year-old white woman

white

woman

a spontaneous nasal septal perforation

antiangiogenic drug, bevacizumab

bevacizumab


Input: Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C.

developed

Two cases are reported of patients

Two

hematologic malignancy

etoglucid, doxorubicin, and mitomycin C.

several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C.

etoglucid

doxorubicin

mitomycin C.

superficial bladder cancer

intravesical chemotherapy

mitomycin C.

doxorubicin

etoglucid


Input: Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).

developed

Eleven patients

Eleven

infection

lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1)

leflunomide

leflunomide


Input: Symptoms and endoscopic lesions quickly regressed within 1 week of meloxicam withdrawal.

regressed

within 1 week of meloxicam withdrawal

Symptoms and endoscopic lesions

1 week

meloxicam


Input: Potential drug interaction between simvastatin and danazol causing rhabdomyolysis.

causing

rhabdomyolysis

drug interaction between simvastatin and danazol

simvastatin

danazol

simvastatin

danazol


Input: Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.

following

Multiple myeloma complicated by congestive heart failure

first administration of recombinant alpha-interferon

recombinant alpha-interferon


Input: Carboplatin hypersensitivity induced by low-dose paclitaxel/carboplatin in multiple platinum-treated patients with recurrent ovarian cancer.

induced

multiple platinum-treated patients with recurrent ovarian cancer

Carboplatin hypersensitivity

low-dose paclitaxel/carboplatin

paclitaxel

carboplatin

platinum

low-dose

recurrent ovarian cancer

paclitaxel

carboplatin


Input: Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C.

developed

patients

a hematologic malignancy

several years after intravesical chemotherapy

with etoglucid, doxorubicin, and mitomycin C.

etoglucid

doxorubicin

mitomycin C.

superficial bladder cancer

several years after

intravesical

mitomycin C.

doxorubicin

etoglucid


Input: CASE SUMMARY: A 46-year-old African-American man experienced recurrent grand mal seizures during intravenous infusion of amphotericin B, then petit mal seizures as the infusion was stopped and the drug concentrations decreased with time.

experienced

A 46-year-old African-American man

African-American

man

recurrent grand mal seizures

intravenous infusion of amphotericin B

intravenous infusion

amphotericin B


Input: Moreover, these findings suggest that the incidence of BOOP following rituximab therapy may be higher than has been previously appreciated.

following

BOOP

rituximab therapy

rituximab


Input: Two cases of hypothyroidism in patients with chronic hepatitis C treated with recombinant alpha interferon are reported.

treated

Two cases

Two

hypothyroidism

recombinant alpha interferon

recombinant alpha interferon

chronic hepatitis C


Input: OBJECTIVE: To report the case of a young woman with Graves' disease in whom ototoxicity developed because of propylthiouracil (PTU)-induced antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.

induced

young woman with Graves' disease

young

woman

ototoxicity developed

propylthiouracil (PTU)

propylthiouracil

Graves' disease


Input: An obese patient, not diabetic, treated with metformin for some weeks, was referred to us with severe inferior digestive hemorrhage, diagnosed with Meckel's diverticulum.

diagnosed

An obese patient, not diabetic

severe inferior digestive hemorrhage

Meckel's diverticulum

metformin for some weeks

metformin

some weeks

obese


Input: Although a lot of amiodarone-induced torsades de pointe have been published, a review of all these cases and the underlying risk-factors has never been made.

induced

torsades de pointe

amiodarone

amiodarone


Input: However, one patient exhibited severe hypersensitivity reactions including cardiac arrest and apnea, and another four patients developed eruptions, hypotension, and tachycardia soon after administration of CBDCA.

administration

one patient

severe hypersensitivity reactions including cardiac arrest and apnea

CBDCA

CBDCA


Input: This report is about three cases of children who developed severe adverse reactions during switching from risperidone to methylphenidate.

developed

three cases of children

three

children

adverse reactions

during switching from risperidone to methylphenidate

risperidone

methylphenidate


Input: This patient, who had a history of osteoarthritis, had severe hepatitis 5 weeks after being started on diclofenac for increasing pain in the joints.

had

This patient, who had a history of osteoarthritis

hepatitis

5 weeks after being started on diclofenac

diclofenac

increasing pain in the joints

5 weeks


Input: She received chemotherapy according to the previously described modified St. Jude total therapy studies XIII.

received

She

She

chemotherapy

chemotherapy


Input: A 17-year-old female patient who had been taking oral minocycline (50 mg twice daily) for 3 weeks for acne developed an eruption that progressed to an exfoliative dermatitis.

developed

A 17-year-old female patient

female

eruption

an exfoliative dermatitis

oral minocycline (50 mg twice daily) for 3 weeks

acne

minocycline

50 mg

twice daily

3 weeks

oral


Input: Risperidone-induced obsessive-compulsive symptoms in two children.

induced

two children

two

children

obsessive-compulsive symptoms

Risperidone

Risperidone


Input: CONCLUSIONS: Cicatrization in the substantia propria of the conjunctiva by excessive lymphocytic infiltration after topically administered antiglaucoma drugs including dipivefrin is a possible mechanism of action for entropion.

mechanism of action

entropion

antiglaucoma drugs including dipivefrin

dipivefrin

antiglaucoma drugs


Input: A patient with the Wolff-Parkinson-White syndrome presented with incessant orthodromic atrioventricular tachycardia following initiation of procainamide therapy.

following

A patient with the Wolff-Parkinson-White syndrome

incessant orthodromic atrioventricular tachycardia

initiation of procainamide therapy

Wolff-Parkinson-White syndrome

procainamide


Input: Hypersensitivity to carboplatin is a rare but real complication of therapy and should be considered in patients presenting with hyperacute changes on ECG whilst receiving carboplatin therapy.

complication

patients presenting with hyperacute changes on ECG

hyperacute changes on ECG

Hypersensitivity to carboplatin

carboplatin therapy

carboplatin


Input: A well-recognized complication of ethambutol use is optic neuropathy, but the potential ocular toxicity of isoniazid is often overlooked.

complication

optic neuropathy

ethambutol

ethambutol


Input: PURPOSE: To report that acute lamotrigine poisoning may result in severe encephalopathy.

result

severe encephalopathy

acute lamotrigine poisoning

lamotrigine


Input: Reversal of ergotamine-induced arteriospasm by mechanical intra-arterial dilatation.

induced

arteriospasm

ergotamine

ergotamine


Input: There have been several case reports of serotonin syndrome from similar combinations of antidepressant and atypical antipsychotic treatment.

from

serotonin syndrome

combinations of antidepressant and atypical antipsychotic treatment

antidepressant

antipsychotic

antidepressant

antipsychotic


Input: We report the first case of a human immunodeficiency virus type 1 (HIV-1)-infected individual receiving combination antiretroviral therapy, which included ritonavir, who developed Cushing syndrome with profound complications after epidural triamcinolone injections.

developed

a human immunodeficiency virus type 1 (HIV-1)-infected individual

Cushing syndrome

combination antiretroviral therapy, which included ritonavir

epidural triamcinolone injections

human immunodeficiency virus type 1

triamcinolone

ritonavir

epidural

injections

ritonavir

triamcinolone


Input: Disulfiram-like reactions with newer cephalosporins: cefmenoxime.

with

Disulfiram-like reactions

cefmenoxime

cefmenoxime


Input: We recommend routine follow up by ECG of patients over the age of 50 treated with carbamazepine.

of

patients over the age of 50

over the age of 50

routine follow up by ECG

carbamazepine


Input: A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported.

for

A 10-year-old girl with Lennox-Gastaut syndrome

Lennox-Gastaut syndrome

girl

intravenous lorazepam

atypical absence status seizures

intravenous

lorazepam


Input: Ritonavir can inhibit the metabolism of fentanyl significantly, so caution should be exercised if fentanyl is given to patients receiving ritonavir medication.

caution

patients receiving ritonavir medication

metabolism of fentanyl significantly

fentanyl

fentanyl

Ritonavir

fentanyl

Ritonavir


Input: This case emphasizes the importance of the evaluation of lithium-associated polyuria with a direct measurement of plasma vasopressin, interpreted with simultaneous plasma and urine osmolality to secure the correct diagnosis and ensure appropriate therapeutic management.

associated

This case

polyuria

lithium

lithium


Input: A patient with chronic myelomonocytic leukemia developed drug-induced pulmonary toxicity after using low dose oral etoposide.

developed

A patient with chronic myelomonocytic leukemia

chronic myelomonocytic leukemia

pulmonary toxicity

using low dose oral etoposide

oral

etoposide

low dose


Input: Alopecia and hair loss are rare side effects of psychotropic drugs.

side effects

Alopecia and hair loss

psychotropic drugs

psychotropic


Input: Occult quinine-induced thrombocytopenia.

induced

thrombocytopenia

quinine

quinine


Input: We report the case of a 17-year-old male who developed chest pain, elevated cardiac biomarkers, and acute left ventricular dysfunction following a single dose of methylphenidate.

following

a 17-year-old male

male

chest pain, elevated cardiac biomarkers, and acute left ventricular dysfunction

a single dose of methylphenidate

a single dose

methylphenidate


Input: In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.

considered

In patients with swallowing dysfunction and pneumonia

ELP

a history of mineral oil use

mineral oil


Input: Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.

induced

ESRD patient on CAPD

ESRD

Agranulocytosis

vancomycin

vancomycin


Input: First case of ivermectin-induced severe hepatitis.

induced

severe hepatitis.

ivermectin

ivermectin


Input: The authors suggest that fluoxetine-induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine-induced akathisia and tricyclic antidepressant-induced "jitteriness" may be identical.

induced

akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission

fluoxetine

fluoxetine


Input: The use of telithromycin in patients receiving multiple doses of oxycodone for pain relief may increase the risk of opioid adverse effects.

increase the risk

patients receiving multiple doses of oxycodone for pain relief

opioid adverse effects

telithromycin

telithromycin


Input: A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.

induced

a 16-year-old girl with cystic fibrosis

cystic fibrosis

girl

oculogyric crisis

metoclopramide

metoclopramide


Input: Supported by a subtherapeutic quinine level, we hypothesise that a drug interaction with phenytoin may compromise the efficacy of quinine in the treatment of malaria.

compromise

efficacy of quinine

phenytoin

quinine

malaria

phenytoin

quinine

phenytoin

quinine


Input: Sporadic rippling muscle disease unmasked by simvastatin.

unmasked

Sporadic rippling muscle disease

simvastatin

simvastatin


Input: An objective causality assessment by use of the Naranjo probability scale revealed that NCSE due to ifosfamide was probable.

due

NCSE

ifosfamide

ifosfamide


Input: Cis-retinoic acid (RA) may further increase the risk of developing BMTN.

developing

BMTN

Cis-retinoic acid (RA)

Cis-retinoic acid


Input: He was later skin tested to confirm allergy to MTX.

to

He

He

allergy

MTX

MTX


Input: Indolent aspergillus arthritis complicating fludarabine-based non-myeloablative stem cell transplantation.

complicating

Indolent aspergillus arthritis

fludarabine

fludarabine


Input: A case of acute cardiomyopathy and pericarditis associated with methylphenidate.

associated

acute cardiomyopathy and pericarditis

methylphenidate

methylphenidate


Input: STUDY DESIGN: Case reports are presented of three premature infants (mean gestational age 27 weeks) cared for in the intensive care nursery in whom clinically significant septal hypertrophy and left ventricular outflow tract obstruction developed during dexamethasone treatment for bronchopulmonary dysplasia.

developed

three premature infants (mean gestational age 27 weeks) cared for in the intensive care nursery

three

premature infants (mean gestational age 27 weeks)

clinically significant septal hypertrophy and left ventricular outflow tract obstruction

during dexamethasone treatment for bronchopulmonary dysplasia

dexamethasone

bronchopulmonary dysplasia.


Input: A case of the Rett syndrome with acute encephalopathy induced during calcium hopantenate treatment.

induced

A case of the Rett syndrome

acute encephalopathy

calcium hopantenate treatment

calcium hopantenate

Rett syndrome


Input: Transient serotonin syndrome caused by concurrent use of tramadol and selective serotonin reuptake inhibitor.

caused

Transient serotonin syndrome

concurrent use of tramadol and selective serotonin reuptake inhibitor

tramadol

selective serotonin reuptake inhibitor

tramadol

selective serotonin reuptake inhibitor


Input: Adverse events associated with IFN alfa-2b use are primarily constitutional symptoms.

associated

primarily constitutional symptoms

IFN alfa-2b

IFN alfa-2b


Input: Sustained-release procainamide-induced reversible granulocytopenia after myocardial infarction.

induced

reversible granulocytopenia

Sustained-release procainamide

procainamide


Input: We describe a patient with M4 AML treated with standard chemotherapy followed by G-CSF who developed marked monocytosis on day 8 of G-CSF therapy.

developed

a patient with M4 AML

marked monocytosis

standard chemotherapy followed by G-CSF

M4 AML

chemotherapy

G-CSF

day 8

chemotherapy

G-CSF


Input: Esophageal candidiasis was diagnosed at endoscopy in two patients receiving omeprazole therapy.

receiving

two patients

two

Esophageal candidiasis

omeprazole therapy

omeprazole


Input: Bisphosphonate induced osteochemonecrosis of the jaw mimicking a tumour.

induced

osteochemonecrosis of the jaw

Bisphosphonate

Bisphosphonate


Input: OBJECTIVES: To describe the clinicopathologic features of 3 patients with CML who rapidly progressed from chronic phase to blast crisis while taking imatinib and to perform a review of the literature.

progressed

3 patients with CML

from chronic phase to blast crisis

imatinib

CML

imatinib


Input: Although they had only a few nodules at diagnosis, the nodules increased in number and size 3 to 4 months after the start of methotrexate therapy in both patients.

after

a few nodules at diagnosis

a few nodules

the nodules increased in number and size

methotrexate therapy

methotrexate

3 to 4 months


Input: CONCLUSIONS: Among the many presentations of ifosfamide neurotoxicity, clinicians should consider NCSE as a possible explanation for changes in consciousness in a patient receiving this agent.

receiving

a patient

neurotoxicity

NCSE

changes in consciousness

ifosfamide

ifosfamide


Input: It is concluded that SIADH is an important side effect of lorcainide therapy.

side effect

SIADH

lorcainide therapy

lorcainide


Input: Hepatoxicity is a rare complication of SRL therapy and may be connected with some diagnostic and/or therapeutic problems.

is

Hepatoxicity

SRL therapy

SRL


Input: A previous study of patients with "quinine-associated TTP/HUS" found that ADAMTS13 activities were not abnormal in 12/12 patients.

associated

12/12 patients

ADAMTS13 activities were not abnormal

TTP/HUS

quinine

quinine


Input: A teenage girl with crescentic glomerulonephritis had antineutrophil cytoplasmic antibody (ANCA) detected after she had received propylthiouracil (PTU) for hyperthyroidism without cutaneous vasculitis.

had

A teenage girl with crescentic glomerulonephritis

crescentic glomerulonephritis

teenage

girl

antineutrophil cytoplasmic antibody (ANCA)

propylthiouracil (PTU)

propylthiouracil

hyperthyroidism without cutaneous vasculitis


Input: Digestive hemorrhage caused by a Meckel's diverticulum in a metformin-treated patient: is there any connection?

treated

patient

Digestive hemorrhage caused by a Meckel's diverticulum

metformin

metformin


Input: Our findings reveal that even in patients without a history of seizures, pregabalin can cause a cortical negative myoclonus.

cause

patients without a history of seizures

cortical negative myoclonus

pregabalin

pregabalin


Input: We describe the first documented case of azathioprine-induced severe myelosuppression due to thiopurine methyltransferase deficiency in autoimmune liver disease.

induced

severe myelosuppression

azathioprine

azathioprine


Input: We report five cases of carboplatin (CBDCA) hypersensitivity after weekly low-dose paclitaxel (60 mg/m2)/CBDCA (area under the concentration curve = 2) therapy in patients with recurrent ovarian cancer receiving multiple platinum-based chemotherapy.

after

patients with recurrent ovarian cancer

five

carboplatin (CBDCA) hypersensitivity

weekly low-dose paclitaxel (60 mg/m2)/CBDCA (area under the concentration curve = 2) therapy

multiple platinum-based chemotherapy

paclitaxel

carboplatin

platinum

low-dose

60 mg/m2)/CBDCA

weekly

recurrent ovarian cancer

chemotherapy

paclitaxel

platinum


Input: The patient was placed on omeprazole after his first cycle of high-dose methotrexate for stress ulcer prophylaxis, and it was discontinued before the start of the first day of the patient's second round of high-dose methotrexate.

prophylaxis,

The patient

methotrexate

stress ulcer

methotrexate

methotrexate

omeprazole

high-dose


Input: Because the patient had been taking lovastatin for the past 12 years, the possibility that the rhabdomyolysis may have been caused by a drug interaction between lovastatin and a concomitant drug was evaluated.

caused

the patient

rhabdomyolysis

lovastatin

lovastatin

lovastatin

12 years


Input: Ibopamine-induced reversible leukopenia during treatment for congestive heart failure.

induced

leukopenia

Ibopamine

congestive heart failure

Ibopamine


Input: A 71-year-old man with paroxysmal atrial fibrillation who had a previous anterior myocardial infarction exhibited granulocytopenia 8 days following the administration of oral sustained-release procainamide (750 mg/day).

exhibited

A 71-year-old man with paroxysmal atrial fibrillation who had a previous anterior myocardial infarction

man

anterior myocardial infarction

granulocytopenia

oral sustained-release procainamide (750 mg/day)

8 days

sustained-release procainamide

oral

750 mg/day

paroxysmal atrial fibrillation


Input: Clinicians should be cognizant of this possibility and consider a diagnosis of HDAs in patients with ongoing thrombosis who are receiving heparin therapy.

receiving

patients

HDAs

thrombosis

heparin

heparin


Input: Rifampin-induced hypothyroidism without underlying thyroid disease.

induced

hypothyroidism without underlying thyroid disease

Rifampin

Rifampin


Input: Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.

precipitation

child with atypical absence seizures

child

Paradoxical precipitation of tonic seizures

lorazepam

absence seizures

lorazepam


Input: Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described.

after

a 70-year-old woman with rheumatoid arthritis

woman

Peculiar nail-changes

penicillamine

rheumatoid arthritis

1 year

penicillamine


Input: Cutaneous vasculitis secondary to ramipril.

secondary

Cutaneous vasculitis

ramipril

ramipril


Input: Multiple mechanisms for ciprofloxacin-induced nephrotoxicity have been proposed.

induced

nephrotoxicity

ciprofloxacin

ciprofloxacin


Input: Pregabalin was added to clozapine in 2 patients with schizophrenia, who both suffered from severe anxiety symptoms.

in

2 patients with schizophrenia, who both suffered from severe anxiety symptoms

Pregabalin was added to clozapine

clozapine

Pregabalin

anxiety symptoms

schizophrenia

Pregabalin

clozapine


Input: Severe hyperkalemia as a complication of timolol, a topically applied beta-adrenergic antagonist.

complication

Severe hyperkalemia

timolol

a topically applied beta-adrenergic antagonist

timolol


Input: Amphotericin B overdose in pediatric patients with associated cardiac arrest.

associated

pediatric patients

pediatric

cardiac arrest

Amphotericin B overdose

Amphotericin B

overdose


Input: Of particular interest is that toxicity only occurred during the second course of FLA and sixth course of Ara-C containing chemotherapy.

occurred

toxicity

second course of FLA and sixth course of Ara-C containing chemotherapy

FLA

Ara-C

sixth course

chemotherapy

FLA

Ara-C


Input: The literature search found 12 cases of radiation recall caused by gemcitabine.

caused

12 cases

radiation recall

gemcitabine

gemcitabine


Input: Two heroin addicts, aged 34 and 19 years, developed ballistic movements after intravenous heroin overdose.

developed

Two heroin addicts, aged 34 and 19 years

Two

heroin addicts

aged 34 and 19 years

ballistic movements

intravenous heroin overdose

heroin

overdose

intravenous


Input: Successful challenge with clozapine in a history of eosinophilia.

with

clozapine

eosinophilia

clozapine


Input: CASE SUMMARY: A 57-year-old female with cardiomyopathy and "sulfa" (trimethoprim/sulfamethoxazole) allergy documented as pancreatitis presented with symptoms consistent with pancreatitis after use of furosemide.

after use

A 57-year-old female with cardiomyopathy and "sulfa" (trimethoprim/sulfamethoxazole) allergy

female

cardiomyopathy

"sulfa" (trimethoprim/sulfamethoxazole) allergy

pancreatitis

furosemide

furosemide


Input: Acute intravascular hemolysis developed when a diabetic patient, previously treated with glyburide, was started on another oral sulfonylurea drug, chlorpropamide.

treated

a diabetic patient

Acute intravascular hemolysis

chlorpropamide

chlorpropamide

diabetic


Input: Intravitreal triamcinolone may have had an influence on the exacerbation of retinochoroiditis in the posterior pole of the patient.

influence

the patient

exacerbation of retinochoroiditis in the posterior pole

Intravitreal triamcinolone

triamcinolone

Intravitreal


Input: We evaluated a patient who developed a psychotic disorder after 4 months of isoniazid prophylaxis for a positive tuberculosis tine test.

developed

patient

psychotic disorder

4 months of isoniazid prophylaxis

isoniazid

4 months

tuberculosis