{
  "dev_config": {
    "max_basal_cells": 10000,
    "min_cells": 40,
    "n_cells_request": 200,
    "n_requests": 300
  },
  "release": "virtual-cell-zeroshot/v1",
  "seed": 20260921,
  "strata_config": {
    "min_cells_measured": 20,
    "strong_quantile": 0.6666666666666666,
    "weak_quantile": 0.3333333333333333,
    "z_threshold": 3.0
  },
  "target_overlap": {
    "ctx_far": {
      "n_never_seen": 81,
      "n_seen_in_training": 219
    },
    "ctx_mid": {
      "n_never_seen": 80,
      "n_seen_in_training": 220
    },
    "ctx_near": {
      "n_never_seen": 80,
      "n_seen_in_training": 220
    }
  },
  "test_config": {
    "max_basal_cells": 10000,
    "max_response_cells": 1000,
    "min_cells_test_target": 40,
    "min_cells_withheld": 20,
    "n_cells_request": {
      "10x_3p_v3": 200,
      "10x_flex": 400,
      "10x_gemx_5p": 200
    },
    "n_leaderboard": 100,
    "n_requests": 300,
    "n_withheld": 80
  },
  "test_contexts": {
    "ctx_far": {
      "chemistry": "10x_flex",
      "n_basal_cells": 10000,
      "n_genes": 18080,
      "n_requests": 300,
      "n_response_cells": 241887,
      "n_withheld": 80,
      "strata_counts": {
        "conserved-strong": 104,
        "context-variable": 136,
        "unmeasured": 5,
        "weak": 55
      },
      "tier": "far"
    },
    "ctx_mid": {
      "chemistry": "10x_3p_v3",
      "n_basal_cells": 10000,
      "n_genes": 8749,
      "n_requests": 300,
      "n_response_cells": 39693,
      "n_withheld": 80,
      "strata_counts": {
        "conserved-strong": 143,
        "context-variable": 141,
        "weak": 16
      },
      "tier": "mid"
    },
    "ctx_near": {
      "chemistry": "10x_3p_v3",
      "n_basal_cells": 4976,
      "n_genes": 9624,
      "n_requests": 300,
      "n_response_cells": 22924,
      "n_withheld": 80,
      "strata_counts": {
        "conserved-strong": 171,
        "context-variable": 118,
        "weak": 11
      },
      "tier": "near"
    }
  },
  "train_contexts": [
    "k562",
    "jurkat",
    "hct116",
    "hek293t"
  ],
  "withheld_targets": {
    "n": 80,
    "note": "removed from every training context; identities are private"
  }
}